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La ricerca find articoli where soggetti phrase all words 'HAIRPIN RIBOZYME' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 180 riferimenti
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    1. Lewin, AS; Hauswirth, WW
      Ribozyme gene therapy: applications for molecular medicine

      TRENDS IN MOLECULAR MEDICINE
    2. Lever, AML
      Gene therapy for HIV

      SEXUALLY TRANSMITTED INFECTIONS
    3. O'Rear, JL; Wang, SL; Feig, AL; Beigelman, L; Uhlenbeck, OC; Herschlag, D
      Comparison of the hammerhead cleavage reactions stimulated by monovalent and divalent cations

      RNA-A PUBLICATION OF THE RNA SOCIETY
    4. Curtis, EA; Bartel, DP
      The hammerhead cleavage reaction in monovalent cations

      RNA-A PUBLICATION OF THE RNA SOCIETY
    5. Tereshko, V; Wallace, ST; Usman, N; Wincott, FE; Egli, M
      X-ray crystallographic observation of "in-line" and "adjacent" conformations in a bulged self-cleaving RNA/DNA hybrid

      RNA-A PUBLICATION OF THE RNA SOCIETY
    6. Burke, JM
      RNA is all you need

      NATURE STRUCTURAL BIOLOGY
    7. Walter, NG
      Structural dynamics of catalytic RNA highlighted by fluorescence resonanceenergy transfer

      METHODS
    8. Hampel, KJ; Burke, JM
      Time-resolved hydroxyl-radical footprinting of RNA using Fe(II)-EDTA

      METHODS
    9. Klostermeier, D; Millar, DP
      RNA conformation and folding studied with fluorescence resonance energy transfer

      METHODS
    10. Buchschacher, GL; Wong-Staal, F
      Approaches to gene therapy for human immunodeficiency virus infection

      HUMAN GENE THERAPY
    11. Butcher, SE
      Structure and function of the small ribozymes

      CURRENT OPINION IN STRUCTURAL BIOLOGY
    12. Lustig, B; Jeang, KT
      Biological applications of hammerhead ribozymes as anti-viral molecules

      CURRENT MEDICINAL CHEMISTRY
    13. Tanaka, T; Inui, O; Dohi, N; Okada, N; Okada, H; Kikuchi, Y
      Is your ribozyme design really correct?: A proposal of simple single turnover competition assay to evaluate ribozymes

      BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
    14. Takagi, Y; Warashina, M; Stec, WJ; Yoshinari, K; Taira, K
      Recent advances in the elucidation of the mechanisms of action of ribozymes

      NUCLEIC ACIDS RESEARCH
    15. Wrzesinski, J; Legiewicz, M; Smolska, B; Ciesiolka, J
      Catalytic cleavage of cis- and trans-acting antigenomic delta ribozymes inthe presence of various divalent metal ions

      NUCLEIC ACIDS RESEARCH
    16. Lafontaine, DA; Norman, DG; Lilley, DMJ
      Structure, folding and activity of the VS ribozyme: importance of the 2-3-6 helical junction

      EMBO JOURNAL
    17. Pinard, R; Hampel, KJ; Heckman, JE; Lambert, D; Chan, PA; Major, F; Burke, JM
      Functional involvement of G8 in the hairpin ribozyme cleavage mechanism

      EMBO JOURNAL
    18. David, L; Lambert, D; Gendron, P; Major, F
      Leadzyme

      RIBONUCLEASES, PT A
    19. Gordon, KHJ; Williams, MR; Baker, JS; Gibson, JM; Bawden, AL; Millgate, AG; Larkin, PJ; Hanzlik, TN
      Replication-independent assembly of an insect virus (Tetraviridae) in plant cells

      VIROLOGY
    20. Lafontaine, DA; Wilson, TJ; Norman, DG; Lilley, DMJ
      The A730 loop is an important component of the active site of the VS ribozyme

      JOURNAL OF MOLECULAR BIOLOGY
    21. Chou, SH; Chin, KH
      Solution structure of a DNA double helix incorporating four consecutive Non-Watson-Crick base-pairs

      JOURNAL OF MOLECULAR BIOLOGY
    22. Yadava, RS; Choi, AJ; Lebruska, LL; Fedor, MJ
      Hairpin ribozymes with four-way helical junctions mediate intracellular RNA ligation

      JOURNAL OF MOLECULAR BIOLOGY
    23. Maguire, JL; Collins, RA
      Effects of cobalt hexammine on folding and self-cleavage of the NeurosporaVS ribozyme

      JOURNAL OF MOLECULAR BIOLOGY
    24. Flinders, J; Dieckmann, T
      A pH controlled conformational switch in the cleavage site of the VS ribozyme substrate RNA

      JOURNAL OF MOLECULAR BIOLOGY
    25. Su, LHJ; Qin, PZ; Michels, WJ; Pyle, AM
      Guiding ribozyme cleavage through motif recognition: The mechanism of cleavage site selection by a group II intron ribozyme

      JOURNAL OF MOLECULAR BIOLOGY
    26. Kato, Y; Kuwabara, T; Warashina, M; Toda, H; Taira, K
      Relationships between the activities in vitro and in vivo of various kindsof ribozyme and their intracellular localization in mammalian cells

      JOURNAL OF BIOLOGICAL CHEMISTRY
    27. Wilson, GM; Sutphen, K; Chuang, KY; Brewer, G
      Folding of A+U-rich RNA elements modulates AUF1 binding - Potential roles in regulation of mRNA turnover

      JOURNAL OF BIOLOGICAL CHEMISTRY
    28. Markley, JC; Godde, F; Sigurdsson, ST
      Identification and characterization of a divalent metal ion-dependent cleavage site in the hammerhead ribozyme

      BIOCHEMISTRY
    29. Lee, N; Suga, H
      Essential roles of innersphere metal ions for the formation of the glutamine binding site in a bifunctional ribozyme

      BIOCHEMISTRY
    30. Vaidya, A; Suga, H
      Diverse roles of metal ions in acyl-transferase ribozymes

      BIOCHEMISTRY
    31. Welz, R; Schmidt, C; Muller, S
      Spermine supports catalysis of hairpin ribozyme variants to differing extents

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    32. Edwards, TE; Okonogi, TM; Robinson, BH; Sigurdsson, ST
      Site-specific incorporation of nitroxide spin-labels into internal sites of the TAR RNA; structure-dependent dynamics of RNA by EPR spectroscopy

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    33. Lilley, DMJ; Wilson, TJ
      Fluorescence resonance energy transfer as a structural tool for nucleic acids

      CURRENT OPINION IN CHEMICAL BIOLOGY
    34. Vitiello, D; Pecchia, DB; Burke, JM
      Intracellular ribozyme-catalyzed trans-cleavage of RNA monitored by fluorescence resonance energy transfer

      RNA-A PUBLICATION OF THE RNA SOCIETY
    35. Kolb, FA; Malmgren, C; Westhof, E; Ehresmann, C; Ehresmann, B; Wagner, EGH; Romby, P
      An unusual structure formed by antisense-target RNA binding involves an extended kissing complex with a four-way junction and a side-by-side helical alignment

      RNA-A PUBLICATION OF THE RNA SOCIETY
    36. James, HA
      Therapeutic potential of ribozymes in haematological disorders

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    37. Hauswirth, WW; Lewin, AS
      Ribozyme uses in retinal gene therapy

      PROGRESS IN RETINAL AND EYE RESEARCH
    38. Jen, KY; Gewirtz, AM
      Suppression of gene expression by targeted disruption of messenger RNA: Available options and current strategies

      STEM CELLS
    39. Toschi, N
      Influence of mRNA self-structure on hybridization: Computational tools forantisense sequence selection

      METHODS-A COMPANION TO METHODS IN ENZYMOLOGY
    40. Klebba, C; Ottmann, OG; Scherr, M; Pape, M; Engels, JW; Grez, M; Hoelzer, D; Klein, SA
      Retrovirally expressed anti-HIV ribozymes confer a selective survival advantage on CD4(+) T cells in vitro

      GENE THERAPY
    41. Alefelder, S; Sigurdsson, ST
      Interstrand disulfide cross-linking of internal sugar residues in duplex RNA

      BIOORGANIC & MEDICINAL CHEMISTRY
    42. Warashina, M; Takagi, Y; Stec, WJ; Taira, K
      Differences among mechanisms of ribozyme-catalyzed reactions

      CURRENT OPINION IN BIOTECHNOLOGY
    43. Kuo, TC; Herrin, DL
      Quantitative studies of Mn2+-promoted specific and non-specific cleavages of a large RNA: Mn2+-GAAA ribozymes and the evolution of small ribozymes

      NUCLEIC ACIDS RESEARCH
    44. Lilley, DMJ
      Analysis of global conformation of branched RNA species using electrophoresis and fluorescence

      RNA-LIGAND INTERACTIONS PT A
    45. Walter, NG; Burke, JM
      Fluorescence assays to study structure, dynamics, and function of RNA and RNA-ligand complexes

      RNA-LIGAND INTERACTIONS PT A
    46. Shaw, LC; Whalen, PO; Drenser, KA; Yan, WM; Hauswirth, WW; Lewin, AS
      Ribozymes in treatment of inherited retinal disease

      VERTEBRATE PHOTOTRANSDUCTION AND THE VISUAL CYCLE, PT B
    47. Castanotto, D; Scherr, M; Rossi, JJ
      Intracellular expression and function of antisense catalytic RNAs

      ANTISENSE TECHNOLOGY, PT A
    48. Tang, J; Breaker, RR
      Structural diversity of self-cleaving ribozymes

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    49. Halatsch, ME; Schmidt, U; Botefur, IC; Holland, JF; Ohnuma, T
      Marked inhibition of glioblastoma target cell tumorigenicity in vitro by retrovirus-mediated transfer of a hairpin ribozyme against deletion-mutant epidermal growth factor receptor messenger RNA

      JOURNAL OF NEUROSURGERY
    50. Stuhmeier, F; Hillisch, A; Clegg, RM; Diekmann, S
      Fluorescence energy transfer analysis of DNA structures containing severalbulges and their interaction with CAP

      JOURNAL OF MOLECULAR BIOLOGY
    51. Nowakowski, J; Shim, PJ; Stout, CD; Joyce, GF
      Alternative conformations of a nucleic acid four-way junction

      JOURNAL OF MOLECULAR BIOLOGY
    52. Walter, NG; Yang, N; Burke, JM
      Probing non-selective cation binding in the hairpin ribozyme with Tb(III)

      JOURNAL OF MOLECULAR BIOLOGY
    53. Fedor, MJ
      Structure and function of the hairpin ribozyme

      JOURNAL OF MOLECULAR BIOLOGY
    54. Donahue, CP; Yadava, RS; Nesbitt, SM; Fedor, MJ
      The kinetic mechanism of the hairpin ribozyme in vivo: Influence of RNA helix stability on intracellular cleavage kinetics

      JOURNAL OF MOLECULAR BIOLOGY
    55. Sargueil, B; McKenna, J; Burke, JM
      Analysis of the functional role of a G center dot A sheared base pair by in vitro genetics

      JOURNAL OF BIOLOGICAL CHEMISTRY
    56. Kilani, AF; Trang, P; Jo, S; Hsu, A; Kim, J; Nepomuceno, E; Liou, K; Liu, FY
      RNase P ribozymes selected in vitro to cleave a viral mRNA effectively inhibit its expression in cell culture

      JOURNAL OF BIOLOGICAL CHEMISTRY
    57. Norman, DG; Grainger, RJ; Uhrin, D; Lilley, DMJ
      Location of cyanine-3 on double-stranded DNA: Importance for fluorescence resonance energy transfer studies

      BIOCHEMISTRY
    58. Bergman, NH; Johnston, WK; Bartel, DP
      Kinetic framework for ligation by an efficient RNA ligase ribozyme

      BIOCHEMISTRY
    59. Wildeson, J; Murphy, CJ
      Intrinsic bending in GGCC tracts as probed by fluorescence resonance energy transfer

      ANALYTICAL BIOCHEMISTRY
    60. Oyelere, AK; Strobel, SA
      Biochemical detection of cytidine protonation within RNA

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    61. Walter, F; Vicens, Q; Westhof, E
      Aminoglycoside - RNA interactions

      CURRENT OPINION IN CHEMICAL BIOLOGY
    62. Carola, C; Eckstein, F
      Nucleic acid enzymes

      CURRENT OPINION IN CHEMICAL BIOLOGY
    63. Shih, IH; Been, MD
      Ribozyme cleavage of a 2 ',5 '-phosphodiester linkage: Mechanism and a restricted divalent metal-ion requirement

      RNA-A PUBLICATION OF THE RNA SOCIETY
    64. Qin, PZF; Pyle, AM
      Site-specific labeling of RNA with fluorophores and other structural probes

      METHODS-A COMPANION TO METHODS IN ENZYMOLOGY
    65. Amado, RG; Mitsuyasu, RT; Symonds, G; Rosenblatt, JD; Zack, J; Sun, LO; Miller, M; Ely, J; Gerlach, W
      A phase I trial of autologous CD34(+) hematopoietic progenitor cells transduced with an anti-HIV ribozyme

      HUMAN GENE THERAPY
    66. Ragheb, JA; Couture, L; Mullen, C; Ridgway, A; Morgan, RA
      Inhibition of human immunodeficiency virus type I by Tat/Rev-regulated expression of cytosine deaminase, interferon alpha 2, or diphtheria toxin compared with inhibition by transdominant Rev

      HUMAN GENE THERAPY
    67. Lian, Y; De Young, MB; Siwkowski, A; Hampel, A; Rappaport, J
      The sCYMV1 hairpin ribozyme: targeting rules and cleavage of heterologous RNA

      GENE THERAPY
    68. Westhof, E; Patel, DJ
      On folded architectures, molecular recognition and catalysis - Editorial overview

      CURRENT OPINION IN STRUCTURAL BIOLOGY
    69. Lilley, DMJ
      Structure, folding and catalysis of the small nucleolytic ribozymes

      CURRENT OPINION IN STRUCTURAL BIOLOGY
    70. Treiber, DK; Williamson, JR
      Exposing the kinetic traps in RNA folding

      CURRENT OPINION IN STRUCTURAL BIOLOGY
    71. Reddy, B; Yin, J
      Quantitative intracellular kinetics of HIV type 1

      AIDS RESEARCH AND HUMAN RETROVIRUSES
    72. Muotri, AR; Pereira, LD; Vasques, LD; Menck, CFM
      Ribozymes and the anti-gene therapy: how a catalytic RNA can be used to inhibit gene function

      GENE
    73. Medina, MFC; Joshi, S
      Design, characterization and testing of tRNA(3)(Lys)-based hammerhead ribozymes

      NUCLEIC ACIDS RESEARCH
    74. Tanner, NK
      Ribozymes: the characteristics and properties of catalytic RNAs

      FEMS MICROBIOLOGY REVIEWS
    75. Gaughan, DJ; Whitehead, AS
      Function and biological applications of catalytic nucleic acids

      BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION
    76. Prokhorenko, IA; Korshun, VA; Berlin, YA
      Fluorescence resonance energy transfer in nucleic acid research

      BIOORGANICHESKAYA KHIMIYA
    77. Kruger, M; Beger, C; Wong-Staal, F
      Use of ribozymes to inhibit gene expression

      EXPRESSION OF RECOMBINANT GENES IN EUKARYOTIC SYSTEMS
    78. Kurz, M; Breaker, RR
      In vitro selection of nucleic acid enzymes

      COMBINATORIAL CHEMISTRY IN BIOLOGY
    79. Koseki, S; Tanabe, T; Tani, K; Asano, S; Shioda, T; Nagai, Y; Shimada, T; Ohkawa, J; Taira, K
      Factors governing the activity in vivo of ribozymes transcribed by RNA polymerase III

      JOURNAL OF VIROLOGY
    80. Nikolcheva, T; Woodson, SA
      Facilitation of group 1 splicing in vivo: Misfolding of the Tetrahymena IVS and the role of ribosomal RNA exons

      JOURNAL OF MOLECULAR BIOLOGY
    81. Young, KJ; Vyle, JS; Pickering, TJ; Cohen, MA; Holmes, SC; Merkel, O; Grasby, JA
      The role of essential pyrimidines in the hairpin ribozyme-catalysed reaction

      JOURNAL OF MOLECULAR BIOLOGY
    82. Grainger, RJ; Norman, DG; Lilley, DMJ
      Binding of U1A protein to the 3 ' untranslated region of its pre-mRNA

      JOURNAL OF MOLECULAR BIOLOGY
    83. Nesbitt, SM; Erlacher, HA; Fedor, MJ
      The internal equilibrium of the hairpin ribozyme: Temperature, ion and pH effects

      JOURNAL OF MOLECULAR BIOLOGY
    84. Lilley, DMJ
      RNA folding and catalysis

      GENETICA
    85. Riepe, A; Beier, H; Gross, HJ
      Enhancement of RNA self-cleavage by micellar catalysis

      FEBS LETTERS
    86. Denman, RB
      Hairpin ribozyme specificity in vivo: A case of promiscuous cleavage

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    87. LIU YH; SYMONS RH
      SPECIFIC RNA SELF-CLEAVAGE IN COCONUT CADANG CADANG VIROID - POTENTIAL FOR A ROLE IN ROLLING CIRCLE REPLICATION

      RNA
    88. CHADWICK DR; LEVER AML
      GENE-THERAPY FOR HIV-INFECTION

      Expert opinion on therapeutic patents
    89. WANG L; WITHERINGTON C; KING A; GERLACH WL; CARR A; PENNY R; COOPER D; SYMONDS G; SUN LQ
      PRECLINICAL CHARACTERIZATION OF AN ANTI-TAT RIBOZYME FOR THERAPEUTIC APPLICATION

      Human gene therapy
    90. MICHIENZI A; CONTI L; VARANO B; PRISLEI S; GESSANI S; BOZZONI I
      INHIBITION OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REPLICATION BY NUCLEAR CHIMERIC ANTI-HIV RIBOZYMES IN A HUMAN T-LYMPHOBLASTOID CELL-LINE

      Human gene therapy
    91. WONGSTAAL F; POESCHLA EM; LOONEY DJ
      A CONTROLLED, PHASE-1 CLINICAL-TRIAL TO EVALUATE THE SAFETY AND EFFECTS IN HIV-1-INFECTED HUMANS OF AUTOLOGOUS LYMPHOCYTES TRANSDUCED WITH A RIBOZYME THAT CLEAVES HIV-1 RNA

      Human gene therapy
    92. PHYLACTOU LA; KILPATRICK MW; WOOD MJA
      RIBOZYMES AS THERAPEUTIC TOOLS FOR GENETIC-DISEASE

      Human molecular genetics (Print)
    93. WELCH PJ; BARBER JR; WONGSTAAL F
      EXPRESSION OF RIBOZYMES IN GENE-TRANSFER SYSTEMS TO MODULATE TARGET RNA LEVELS

      Current opinion in biotechnology
    94. KIGA D; FUTAMURA Y; SAKAMOTO K; YOKOYAMA S
      AN RNA APTAMER TO THE XANTHINE GUANINE BASE WITH A DISTINCTIVE MODE OF PURINE RECOGNITION/

      Nucleic acids research
    95. DRENSER KA; TIMMERS AM; HAUSWIRTH WW; LEWIN AS
      RIBOZYME-TARGETED DESTRUCTION OF RNA ASSOCIATED WITH AUTOSOMAL-DOMINANT RETINITIS-PIGMENTOSA

      Investigative ophthalmology & visual science
    96. RANGA U; WOFFENDIN C; VERMA S; XU L; JUNE CH; BISHOP DK; NABEL GJ
      ENHANCED T-CELL ENGRAFTMENT AFTER RETROVIRAL DELIVERY OF AN ANTIVIRALGENE IN HIV-INFECTED INDIVIDUALS

      Proceedings of the National Academy of Sciences of the United Statesof America
    97. LEONTIS NB; WESTHOF E
      A COMMON MOTIF ORGANIZES THE STRUCTURE OF MULTI-HELIX LOOPS IN 16-S AND 23-S RIBOSOMAL-RNAS

      Journal of Molecular Biology
    98. HOCH I; BERENS C; WESTHOF E; SCHROEDER R
      ANTIBIOTIC INHIBITION OF RNA CATALYSIS - NEOMYCIN-B BINDS TO THE CATALYTIC CORE OF THE TD GROUP-I INTRON DISPLACING ESSENTIAL METAL-IONS

      Journal of Molecular Biology
    99. RASTOGI T; COLLINS RA
      SMALLER, FASTER RIBOZYMES REVEAL THE CATALYTIC CORE OF NEUROSPORA VS RNA

      Journal of Molecular Biology
    100. KOMATSU Y; SHIRAI M; OHTSUKA E
      MODIFICATION AND APPLICATION OF SELF-TRIMMING HAIRPIN RIBOZYMES TO TARGETING A TRANSCRIBED RNA IN-VITRO

      Journal of Biochemistry (Tokyo)


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Documento generato il 15/08/20 alle ore 02:06:12