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    1. Agrawal, DK
      Pharmacology and clinical efficacy of desloratadine as an anti-allergic and anti-inflammatory drug

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    2. Pype, JL; Xu, HY; Schuermans, M; Dupont, LJ; Wuyts, W; Mak, JCW; Barnes, PJ; Demedts, MG; Verleden, GM
      Mechanisms of interleukin 1 beta-induced human airway smooth muscle hyporesponsiveness to histamine - Involvement of p38 MAPK and NF-kappa B

      AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    3. Horton, JR; Sawada, K; Nishibori, M; Zhang, X; Cheng, XD
      Two polymorphic forms of human histamine methyltransferase: Structural, thermal and kinetic comparisons

      STRUCTURE
    4. Schroeder, JT; Schleimer, RP; Lichtenstein, LM; Kreutner, W
      Inhibition of cytokine generation and mediator release by human basophils treated with desloratadine

      CLINICAL AND EXPERIMENTAL ALLERGY
    5. Furue, M; Terao, H; Koga, T
      Effects of cetirizine and epinastine on the skin response to histamine iontophoresis

      JOURNAL OF DERMATOLOGICAL SCIENCE
    6. Mollet, A; Lutz, TA; Meier, S; Riediger, T; Rushing, PA; Scharrer, E
      Histamine H-1 receptors mediate the anorectic action of the pancreatic hormone amylin

      AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
    7. Tagawa, M; Kano, M; Okamura, N; Higuchi, M; Matsuda, M; Mizuki, Y; Arai, H; Iwata, R; Fujii, T; Komemushi, S; Ido, T; Itoh, M; Sasaki, H; Watanabe, T; Yanai, K
      Neuroimaging of histamine H-1-receptor occupancy in human brain by positron emission tomography (PET): A comparative study of ebastine, a second-generation antihistamine, and (+)-chlorpheniramine, a classical antihistamine

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    8. Morimoto, T; Yamamoto, Y; Yamatodani, A
      Brain histamine and feeding behavior

      BEHAVIOURAL BRAIN RESEARCH
    9. Philippu, A; Prast, H
      Importance of histamine in modulatory processes, locomotion and memory

      BEHAVIOURAL BRAIN RESEARCH
    10. Ten Eick, AP; Blumer, JL; Reed, MD
      Safety of antihistamines in children

      DRUG SAFETY
    11. Papi, A; Papadopoulos, NG; Stanciu, LA; Degitz, K; Holgate, ST; Johnston, SL
      Effect of desloratadine and loratadine on rhinovirus-induced intercellularadhesion molecule 1 upregulation and promoter activation in respiratory epithelial cells

      JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
    12. Estelle, F; Simons, R
      Prevention of acute urticaria in young children with atopic dermatitis

      JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
    13. Simons, FER; Silver, NA; Gu, XC; Simons, KJ
      Skin concentrations of H-1-receptor antagonists

      JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
    14. De Ponti, F; Poluzzi, E; Montanaro, N
      Organising evidence on QT prolongation and occurrence of Torsades de Pointes with non-antiarrhythmic drugs: A call for consensus

      EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
    15. Shamsi, Z; Kimber, S; Hindmarch, I
      An investigation into the effects of cetirizine on cognitive function and psychomotor performance in healthy volunteers

      EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
    16. Schlicker, E; Kozlowska, H; Kwolek, G; Malinowska, B; Kramer, K; Pertz, HH; Elz, S; Schunack, W
      Novel histaprodifen analogues as potent histamine H-1-receptor agonists inthe pithed and in the anaesthetized rat

      NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
    17. Bakker, RA; Schoonus, SBJ; Smit, MJ; Timmerman, H; Leurs, R
      Histamine H-1-receptor activation of nuclear factor-kappa B: Roles for G beta gamma- and G alpha(q/11)-subunits in constitutive and agonist-mediated signaling

      MOLECULAR PHARMACOLOGY
    18. Attoub, S; Moizo, L; Sobhani, I; Laigneau, JP; Lewin, MJM; Bado, A
      The H-3 receptor is involved in cholecystokinin inhibition of food intake in rats

      LIFE SCIENCES
    19. Ruck, LM; Rizzo, CA; Anthes, JC; Eckel, S; Egan, RW; Cuss, FM; Hey, JA
      Synergistic antiallergic activity of combined histamine H-1- and cysteinylleukotriene(1)-receptor blockade in human bronchus

      LIFE SCIENCES
    20. Taga, C; Sugimoto, Y; Nishiga, M; Fujii, Y; Kamei, C
      Effects of vasopressin on histamine H-1 receptor antagonist-induced spatial memory deficits in rats

      EUROPEAN JOURNAL OF PHARMACOLOGY
    21. Walsh, GM; Annunziato, L; Frossard, N; Knol, K; Levander, S; Nicolas, JM; Taglialatela, M; Tharp, MD; Tillement, JP; Timmerman, H
      New insights into the second generation antihistamines

      DRUGS
    22. Robinson, AJ; Dickenson, JM
      Activation of the p38 and p42/p44 families by the histamine H-1 receptor mitogen-activated protein kinase in DDT1MF-2 cells

      BRITISH JOURNAL OF PHARMACOLOGY
    23. Endou, M; Yanai, K; Sakurai, E; Fukudo, S; Hongo, M; Watanabe, T
      Food-deprived activity stress decreased the activity of the histaminergic neuron system in rats

      BRAIN RESEARCH
    24. Shishoo, CJ; Shirsath, VS; Rathod, IS; Patil, MJ; Bhargava, SS
      Design, synthesis and antihistaminic (H-1) activity of some condensed 2-(substituted) arylaminoethylpyrimidin-4(3H)-ones

      ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH
    25. Choi, SO; Lee, SH; Kong, HS; Kim, EJ; Choo, HYP
      Stereoselective determination of cetirizine and studies on pharmacokinetics in rat plasma

      JOURNAL OF CHROMATOGRAPHY B
    26. Philpot, EE
      Safety of second generation antihistamines

      ALLERGY AND ASTHMA PROCEEDINGS
    27. Alper, BS
      Choice of antihistamines for urticaria

      ARCHIVES OF FAMILY MEDICINE
    28. Lorette, G; Giannetti, A; Pereira, RS; Leynadier, F; Murrieta-Aguttes, M
      One-year treatment of chronic urticaria with mizolastine: efficacy and safety

      JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
    29. Simons, FER; Johnston, L; Simons, KJ
      Clinical pharmacology of the H-1-receptor antagonists cetirizine and loratadine in children

      PEDIATRIC ALLERGY AND IMMUNOLOGY
    30. Gentile, DA; Friday, GA; Skoner, DP
      Management of allergic rhinitis - Antihistamines and decongestants

      IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA
    31. Shamsi, Z; Hindmarch, I
      Sedation and antihistamines: A review of inter-drug differences using proportional impairment ratios

      HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL
    32. Simons, FER
      Prospective, long-term safety evaluation of the H-1-receptor antagonist cetirizine in very young children with atopic dermatitis

      ALLERGOLOGIE
    33. Pradalier, A; Campinos, C; Barzegar, C; Vincent, D
      Cardiovascular side-effects of antihistamines

      REVUE FRANCAISE D ALLERGOLOGIE ET D IMMUNOLOGIE CLINIQUE
    34. Bindslev-Jensen, C
      Do sedating H-1-antihistamines still have a role to play in the managementof chronic idiopathic urticaria?

      REVUE FRANCAISE D ALLERGOLOGIE ET D IMMUNOLOGIE CLINIQUE
    35. Bousquet, J
      What are the perspectives in the future for H-1-antihistamines?

      REVUE FRANCAISE D ALLERGOLOGIE ET D IMMUNOLOGIE CLINIQUE
    36. Kurita, M; Mashiko, H; Ogata, M; Kumasaka, T; Niwa, S; Nakahata, N; Takano, S; Nakanishi, H
      Discrimination of histamine H-1 and muscarinic receptor-mediated signalling pathways by phorbol ester in human astrocytoma cells

      CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
    37. Giede, C; Metzenauer, P; Petzold, U; Ellers-Lenz, B
      Comparison of azelastine eye drops with levocabastine eye drops in the treatment of seasonal allergic conjunctivitis

      CURRENT MEDICAL RESEARCH AND OPINION
    38. Shishoo, CJ; Shirsath, VS; Rathod, IS; Yande, VD
      Design, synthesis and antihistaminic (H-1) activity of some condensed 3-aminopyrimidin-4(3H)-ones

      EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
    39. Elz, S; Kramer, K; Leschke, C; Schunack, W
      Ring-substituted histaprodifen analogues as partial agonists for histamineH-1 receptors: synthesis and structure-activity relationships

      EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
    40. Kjaer, A; Knigge, U; Jorgensen, H; Warberg, J
      Dehydration-induced vasopressin secretion in humans: involvement of the histaminergic system

      AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
    41. Mizumura, K; Koda, H; Kumazawa, T
      Possible contribution of protein kinase C in the effects of histamine on the visceral nociceptor activities in vitro

      NEUROSCIENCE RESEARCH
    42. Goren, N; Sterin-Borda, L; Bartrons, R; Gomez, R; Borda, E
      Detection of mRNA encoding H-1 receptor and iNOS by RT-PCR in autoimmune myocarditis with special reference to changes in heart contractility

      INTERNATIONAL JOURNAL OF CARDIOLOGY
    43. Yoshida, T; Iwakiri, R; Noda, T; Okamoto, K; Kojima, M; Fukuyama, K; Fujimoto, K
      Histaminergic effect on apoptosis of rat small intestinal mucosa after ischemia-reperfusion

      DIGESTIVE DISEASES AND SCIENCES
    44. Sugimoto, Y; Kawamoto, E; Chen, Z; Kamei, C
      A new model of allergic rhinitis in rats by topical sensitization and evaluation of H-1-receptor antagonists

      IMMUNOPHARMACOLOGY
    45. Salmun, LM; Gates, D; Scharf, M; Greiding, L; Ramon, F; Heithoff, K
      Loratadine versus cetirizine: Assessment of somnolence and motivation during the workday

      CLINICAL THERAPEUTICS
    46. Abdelaziz, MM; Khair, OA; Devalia, JL
      The potential of active metabolites of antihistamines in the management ofallergic disease

      ALLERGY
    47. Baroody, FM; Naclerio, RM
      Antiallergic effects of H-1-receptor antagonists

      ALLERGY
    48. Timmerman, H
      Factors involved in the absence of sedative effects by the second-generation antihistamines

      ALLERGY
    49. Meltzer, EO; Malmstrom, K; Lu, S; Prenner, BM; Wei, LX; Weinstein, SF; Wolfe, JD; Reiss, TF
      Concomitant montelukast and loratadine as treatment for seasonal allergic rhinitis: A randomized, placebo-controlled clinical trial

      JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
    50. Hughes, SACF; Gibson, WJ; Young, JM
      The interaction of U-73122 with the histamine H-1 receptor: implications for the use of U-73122 in defining H-1 receptor-coupled signalling pathways

      NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
    51. Franken, C; Trankle, C; Mohr, K
      Testing the specificity of allosteric modulations of muscarinic: receptorsin phylogenetically closely related histamine H-1-receptors

      NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
    52. Richelson, E; Souder, T
      Binding of antipsychotic drugs to human brain receptors - Focus on newer generation compounds

      LIFE SCIENCES
    53. Singh, N; Puri, SK
      Modulation of halofantrine resistance after coadministration of halofantrine with diverse pharmacological agents in a rodent malaria model

      LIFE SCIENCES
    54. Nakazato, E; Yamamoto, T; Ohno, M; Watanabe, S
      Cholinergic and glutamatergic activation reverses working memory failure by hippocampal histamine H-1 receptor blockade in rats

      LIFE SCIENCES
    55. Hishinuma, S; Ogura, K
      Ca2+/calmodulin-mediated regulation of the desensitizing process in G(q) protein-coupled histamine H-1 receptor-mediated Ca2+ responses in human U373MG astrocytoma cells

      JOURNAL OF NEUROCHEMISTRY
    56. Elz, S; Kramer, K; Pertz, HH; Detert, H; ter Laak, AM; Kuhne, R; Schunack, W
      Histaprodifens: Synthesis, pharmacological in vitro evaluation, and molecular modeling of a new class of highly active and selective histamine H-1-receptor agonists

      JOURNAL OF MEDICINAL CHEMISTRY
    57. Crivori, P; Cruciani, G; Carrupt, PA; Testa, B
      Predicting blood-brain barrier permeation from three-dimensional molecularstructure

      JOURNAL OF MEDICINAL CHEMISTRY
    58. Walczynski, K; Guryn, R; Zuiderveld, OP; Zhang, MQ; Timmerman, H
      Histamine H-1 receptor ligands Part II. Synthesis and in vitro pharmacology of 2-[2-(phenylamino)thiazol-4-yl]ethanamine and 2-(2-benzhydrylthiazol-4-yl)ethanamine derivatives

      FARMACO
    59. Inagaki, N; Nagao, M; Nakamura, N; Kawasaki, H; Igeta, K; Musoh, K; Nagai, H
      Evaluation of anti-scratch properties of oxatomide and epinastine in mice

      EUROPEAN JOURNAL OF PHARMACOLOGY
    60. Mobarakeh, JI; Sakurada, S; Katsuyama, S; Kutsuwa, M; Kuramasu, A; Lin, ZY; Watanabe, T; Hashimoto, Y; Watanabe, T; Yanai, K
      Of histamine H-1 receptor in pain perception: a study of the receptor geneknockout mice

      EUROPEAN JOURNAL OF PHARMACOLOGY
    61. Bakker, RA; Wieland, K; Timmerman, H; Leurs, R
      Constitutive activity of the histamine H-1 receptor reveals inverse agonism of histamine H-1 receptor antagonists

      EUROPEAN JOURNAL OF PHARMACOLOGY
    62. Hurst, M; Spencer, CM
      Ebastine - An update of its use in allergic disorders

      DRUGS
    63. Hamelin, BA; Bouayad, A; Methot, J; Jobin, J; Desgagnes, P; Poirier, P; Allaire, J; Dumesnil, J; Turgeon, J
      Significant interaction between the nonprescription antihistamine diphenhydramine and the CYP2D6 substrate metoprolol in healthy men with high or lowCYP2D6 activity

      CLINICAL PHARMACOLOGY & THERAPEUTICS
    64. Gilbert, JD; Cahill, SA; McCartney, DG; Lukas, A; Gross, GJ
      Predictors of Torsades de Pointes in rabbit ventricles perfused with sedating and nonsedating histamine H-1-receptor antagonists

      CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
    65. Taglialatela, M; Pannaccione, A; Castaldo, P; Giorgio, G; Annunziato, L
      Inhibition of HERG1 K+ channels by the novel second-generation antihistamine mizolastine

      BRITISH JOURNAL OF PHARMACOLOGY
    66. Chambers, RJ; Marfat, A
      Leukotriene antagonists: patent highlights 1996-1998

      EXPERT OPINION ON THERAPEUTIC PATENTS
    67. Meltzer, EO; Grant, JA
      Impact of cetirizine on the burden of allergic rhinitis

      ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY
    68. Zuberbier, T; Henz, BM
      Use of cetirizine in dermatologic disorders

      ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY
    69. Meltzer, EO; Casale, TB; Nathan, RA; Thompson, AK
      Once-daily fexofenadine HCl improves quality of life and reduces work and activity impairment in patients with seasonal allergic rhinitis

      ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY
    70. Privou, C; Li, JS; Hasenohrl, RU; Huston, JP
      Enhanced learning by posttrial injection of H-1- but not H-2-histaminergicantagonists into the nucleus basalis magnocellularis region

      NEUROBIOLOGY OF LEARNING AND MEMORY
    71. Schaefer, U; Schmitz, V; Schneider, A; Neugebauer, E
      Histamine induced homologous and heterologous regulation of histamine receptor subtype mRNA expression in cultured endothelial cells

      SHOCK
    72. Zhou, ZF; Vorperian, VR; Gong, QM; Zhang, ST; January, CT
      Block of HERG potassium channels by the antihistamine astemizole and its metabolites desmethylastemizole and norastemizole

      JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
    73. Kimura, K; Adachi, M; Kubo, K
      H-1- and H-2-receptor antagonists prevent histamine release in allergic patients after the administration of midazolam-ketamine. A randomized controlled study

      INFLAMMATION RESEARCH
    74. Stone, BM; Turner, C; Mills, SL; Nicholson, AN
      Studies into the possible central effects of the H-1 receptor antagonist, fexofenadine

      INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
    75. Kaminski, JJ; Carruthers, NI; Wong, SC; Chan, TM; Billah, MM; Tozzi, S; McPhail, AT
      Conformational considerations in the design of dual antagonists of platelet-activating factor (PAF) and histamine

      BIOORGANIC & MEDICINAL CHEMISTRY
    76. Hayashi, S; Hashimoto, S
      Anti-inflammatory actions of new antihistamines

      CLINICAL AND EXPERIMENTAL ALLERGY
    77. Timmerman, H
      Why are non-sedating antihistamines non-sedating?

      CLINICAL AND EXPERIMENTAL ALLERGY
    78. Smit, MJ; Hoffmann, M; Timmerman, H; Leurs, R
      Molecular properties and signalling pathways of the histamine H-1 receptor

      CLINICAL AND EXPERIMENTAL ALLERGY
    79. Cuss, FM
      Beyond the histamine receptor: effect of antihistamines on mast cells

      CLINICAL AND EXPERIMENTAL ALLERGY
    80. Howarth, PH
      Assessment of antihistamine efficacy and potency

      CLINICAL AND EXPERIMENTAL ALLERGY
    81. Hindmarch, I; Shamsi, Z
      Antihistamines: models to assess sedative properties, assessment of sedation, safety and other side-effects

      CLINICAL AND EXPERIMENTAL ALLERGY
    82. Kim, SE; Szabo, Z; Seki, C; Ravert, HT; Scheffel, U; Dannals, RF; Wagner, HN
      Effect of tracer metabolism on PET measurement of [C-11]pyrilamine bindingto histamine H-1 receptors

      ANNALS OF NUCLEAR MEDICINE
    83. Blazso, G; Razga, Z; Gabor, M
      Effects of cinnarizine on different experimentally induced oedemas

      FUNDAMENTAL & CLINICAL PHARMACOLOGY
    84. Furukawa, M; Suzuki, H; Ikeda, K; Oshima, T; Yamaya, M; Sasaki, H; Takasaka, T
      Kinin and histamine stimulate Cl- secretion in gerbil middle ear epithelium: connection to otitis media

      HEARING RESEARCH
    85. Simons, FER
      Clinical pharmacology of new H-1-receptor antagonists, and why it matters

      REVUE FRANCAISE D ALLERGOLOGIE ET D IMMUNOLOGIE CLINIQUE
    86. Bayramgurler, D; Bilen, N; Apaydyn, R; Altintas, L; Sal, G; Dokmeci, S; Utkan, T
      Effects of acrivastine, loratadine and cetirizine on histamine-induced wheal and flare responses

      CLINICAL AND EXPERIMENTAL DERMATOLOGY
    87. Hindmarch, I; Shamsi, Z; Stanley, N; Fairweather, DB
      A double-blind, placebo-controlled investigation of the effects of fexofenadine, loratadine and promethazine on cognitive and psychomotor function

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    88. Chaufour, S; Caplain, H; Lilienthal, N; L'Heritier, C; Deschamps, C; Dubruc, C; Rosenzweig, P
      Study of cardiac repolarization in healthy volunteers performed with mizolastine, a new H-1-receptor antagonist

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    89. Kubota, Y; Ito, C; Kuramasu, A; Sato, M; Watanabe, T
      Transient increases of histamine H-1 and H-2 receptor mRNA levels in the rat striatum after the chronic administration of methamphetamine

      NEUROSCIENCE LETTERS
    90. Dendorfer, A; Fitschen, M; Raasch, W; Tempel, K; Dominiak, P
      Mechanisms of bradykinin-induced catecholamine release in pithed spontaneously hypertensive rats

      IMMUNOPHARMACOLOGY
    91. DuBuske, LM
      Second-generation antihistamines: The risk of ventricular arrhythmias

      CLINICAL THERAPEUTICS
    92. Arai, M; Chiba, S
      Endothelium-dependent vasodilatation mechanisms by histamine in simian butnot in canine femoral arterial branches

      JOURNAL OF AUTONOMIC PHARMACOLOGY
    93. Segarra, V; Lopez, M; Ryder, H; Palacios, JM; Roberts, DJ
      Computer-assisted comparison of the structural and electronic dispositionsof ebastine and terfenadine

      DRUG SAFETY
    94. Horak, F; Stubner, UP
      Comparative tolerability of second generation antihistamines

      DRUG SAFETY
    95. Simons, FER
      Prospective, long-term safety evaluation of the H-1-receptor antagonist cetirizine in very young children with atopic dermatitis

      JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
    96. Sussman, GL; Mason, J; Compton, D; Stewart, J; Ricard, N
      The efficacy and safety of fexofenadine HCl and pseudoephedrine, alone andin combination, in seasonal allergic rhinitis

      JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
    97. Corren, J; Rachelefsky, G; Spector, S; Schanker, H; Siegel, S; Holton, D; Karcher, K; Travers, S
      Onset and duration of action of levocabastine nasal spray in atopic patients under nasal challenge conditions

      JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
    98. Simons, FER; Roberts, JR; Gu, XC; Kapur, S; Simons, KJ
      The clinical pharmacology of brompheniramine in children

      JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
    99. Rossi, R; Del Prete, E; Scharrer, E
      Effect of the H-1-histamine receptor agonist betahistine on drinking and eating behavior in pygmy goats

      PHYSIOLOGY & BEHAVIOR
    100. Malinowska, B; Piszcz, J; Schlicker, E; Kramer, K; Elz, S; Schunack, W
      Histaprodifen, methylhistaprodifen, and dimethylhistaprodifen are potent H-1-receptor agonists in the pithed and in the anaesthetized rat

      NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY


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Documento generato il 23/01/21 alle ore 12:24:32