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1. Agrawal, DK
   Pharmacology and clinical efficacy of desloratadine as an anti-allergic and anti-inflammatory drug
   EXPERT OPINION ON INVESTIGATIONAL DRUGS
   
   D.K. Agrawal, "Pharmacology and clinical efficacy of desloratadine as an anti-allergic and anti-inflammatory drug", EXPERT OP I, 10(3), 2001, pp. 547-560
2. Pype, JL; Xu, HY; Schuermans, M; Dupont, LJ; Wuyts, W; Mak, JCW; Barnes, PJ; Demedts, MG; Verleden, GM
   Mechanisms of interleukin 1 beta-induced human airway smooth muscle hyporesponsiveness to histamine - Involvement of p38 MAPK and NF-kappa B
   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
   
   J.L. Pype et al., "Mechanisms of interleukin 1 beta-induced human airway smooth muscle hyporesponsiveness to histamine - Involvement of p38 MAPK and NF-kappa B", AM J R CRIT, 163(4), 2001, pp. 1010-1017
3. Horton, JR; Sawada, K; Nishibori, M; Zhang, X; Cheng, XD
   Two polymorphic forms of human histamine methyltransferase: Structural, thermal and kinetic comparisons
   STRUCTURE
   
   J.R. Horton et al., "Two polymorphic forms of human histamine methyltransferase: Structural, thermal and kinetic comparisons", STRUCTURE, 9(9), 2001, pp. 837-849
4. Schroeder, JT; Schleimer, RP; Lichtenstein, LM; Kreutner, W
   Inhibition of cytokine generation and mediator release by human basophils treated with desloratadine
   CLINICAL AND EXPERIMENTAL ALLERGY
   
   J.T. Schroeder et al., "Inhibition of cytokine generation and mediator release by human basophils treated with desloratadine", CLIN EXP AL, 31(9), 2001, pp. 1369-1377
5. Furue, M; Terao, H; Koga, T
   Effects of cetirizine and epinastine on the skin response to histamine iontophoresis
   JOURNAL OF DERMATOLOGICAL SCIENCE
   
   M. Furue et al., "Effects of cetirizine and epinastine on the skin response to histamine iontophoresis", J DERMA SCI, 25(1), 2001, pp. 59-63
6. Mollet, A; Lutz, TA; Meier, S; Riediger, T; Rushing, PA; Scharrer, E
   Histamine H-1 receptors mediate the anorectic action of the pancreatic hormone amylin
   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
   
   A. Mollet et al., "Histamine H-1 receptors mediate the anorectic action of the pancreatic hormone amylin", AM J P-REG, 281(5), 2001, pp. R1442-R1448
7. Tagawa, M; Kano, M; Okamura, N; Higuchi, M; Matsuda, M; Mizuki, Y; Arai, H; Iwata, R; Fujii, T; Komemushi, S; Ido, T; Itoh, M; Sasaki, H; Watanabe, T; Yanai, K
   Neuroimaging of histamine H-1-receptor occupancy in human brain by positron emission tomography (PET): A comparative study of ebastine, a second-generation antihistamine, and (+)-chlorpheniramine, a classical antihistamine
   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
   
   M. Tagawa et al., "Neuroimaging of histamine H-1-receptor occupancy in human brain by positron emission tomography (PET): A comparative study of ebastine, a second-generation antihistamine, and (+)-chlorpheniramine, a classical antihistamine", BR J CL PH, 52(5), 2001, pp. 501-509
8. Morimoto, T; Yamamoto, Y; Yamatodani, A
   Brain histamine and feeding behavior
   BEHAVIOURAL BRAIN RESEARCH
   
   T. Morimoto et al., "Brain histamine and feeding behavior", BEH BRA RES, 124(2), 2001, pp. 145-150
9. Philippu, A; Prast, H
   Importance of histamine in modulatory processes, locomotion and memory
   BEHAVIOURAL BRAIN RESEARCH
   
   A. Philippu e H. Prast, "Importance of histamine in modulatory processes, locomotion and memory", BEH BRA RES, 124(2), 2001, pp. 151-159
10. Ten Eick, AP; Blumer, JL; Reed, MD
    Safety of antihistamines in children
    DRUG SAFETY
    
    A.P. Ten Eick et al., "Safety of antihistamines in children", DRUG SAFETY, 24(2), 2001, pp. 119-147
11. Papi, A; Papadopoulos, NG; Stanciu, LA; Degitz, K; Holgate, ST; Johnston, SL
    Effect of desloratadine and loratadine on rhinovirus-induced intercellularadhesion molecule 1 upregulation and promoter activation in respiratory epithelial cells
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
    
    A. Papi et al., "Effect of desloratadine and loratadine on rhinovirus-induced intercellularadhesion molecule 1 upregulation and promoter activation in respiratory epithelial cells", J ALLERG CL, 108(2), 2001, pp. 221-228
12. Estelle, F; Simons, R
    Prevention of acute urticaria in young children with atopic dermatitis
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
    
    F. Estelle e R. Simons, "Prevention of acute urticaria in young children with atopic dermatitis", J ALLERG CL, 107(4), 2001, pp. 703-706
13. Simons, FER; Silver, NA; Gu, XC; Simons, KJ
    Skin concentrations of H-1-receptor antagonists
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
    
    F.E.R. Simons et al., "Skin concentrations of H-1-receptor antagonists", J ALLERG CL, 107(3), 2001, pp. 526-530
14. De Ponti, F; Poluzzi, E; Montanaro, N
    Organising evidence on QT prolongation and occurrence of Torsades de Pointes with non-antiarrhythmic drugs: A call for consensus
    EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
    
    F. De Ponti et al., "Organising evidence on QT prolongation and occurrence of Torsades de Pointes with non-antiarrhythmic drugs: A call for consensus", EUR J CL PH, 57(3), 2001, pp. 185-209
15. Shamsi, Z; Kimber, S; Hindmarch, I
    An investigation into the effects of cetirizine on cognitive function and psychomotor performance in healthy volunteers
    EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
    
    Z. Shamsi et al., "An investigation into the effects of cetirizine on cognitive function and psychomotor performance in healthy volunteers", EUR J CL PH, 56(12), 2001, pp. 865-871
16. Schlicker, E; Kozlowska, H; Kwolek, G; Malinowska, B; Kramer, K; Pertz, HH; Elz, S; Schunack, W
    Novel histaprodifen analogues as potent histamine H-1-receptor agonists inthe pithed and in the anaesthetized rat
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
    
    E. Schlicker et al., "Novel histaprodifen analogues as potent histamine H-1-receptor agonists inthe pithed and in the anaesthetized rat", N-S ARCH PH, 364(1), 2001, pp. 14-20
17. Bakker, RA; Schoonus, SBJ; Smit, MJ; Timmerman, H; Leurs, R
    Histamine H-1-receptor activation of nuclear factor-kappa B: Roles for G beta gamma- and G alpha(q/11)-subunits in constitutive and agonist-mediated signaling
    MOLECULAR PHARMACOLOGY
    
    R.A. Bakker et al., "Histamine H-1-receptor activation of nuclear factor-kappa B: Roles for G beta gamma- and G alpha(q/11)-subunits in constitutive and agonist-mediated signaling", MOLEC PHARM, 60(5), 2001, pp. 1133-1142
18. Attoub, S; Moizo, L; Sobhani, I; Laigneau, JP; Lewin, MJM; Bado, A
    The H-3 receptor is involved in cholecystokinin inhibition of food intake in rats
    LIFE SCIENCES
    
    S. Attoub et al., "The H-3 receptor is involved in cholecystokinin inhibition of food intake in rats", LIFE SCI, 69(4), 2001, pp. 469-478
19. Ruck, LM; Rizzo, CA; Anthes, JC; Eckel, S; Egan, RW; Cuss, FM; Hey, JA
    Synergistic antiallergic activity of combined histamine H-1- and cysteinylleukotriene(1)-receptor blockade in human bronchus
    LIFE SCIENCES
    
    L.M. Ruck et al., "Synergistic antiallergic activity of combined histamine H-1- and cysteinylleukotriene(1)-receptor blockade in human bronchus", LIFE SCI, 68(25), 2001, pp. 2825-2834
20. Taga, C; Sugimoto, Y; Nishiga, M; Fujii, Y; Kamei, C
    Effects of vasopressin on histamine H-1 receptor antagonist-induced spatial memory deficits in rats
    EUROPEAN JOURNAL OF PHARMACOLOGY
    
    C. Taga et al., "Effects of vasopressin on histamine H-1 receptor antagonist-induced spatial memory deficits in rats", EUR J PHARM, 423(2-3), 2001, pp. 167-170
21. Walsh, GM; Annunziato, L; Frossard, N; Knol, K; Levander, S; Nicolas, JM; Taglialatela, M; Tharp, MD; Tillement, JP; Timmerman, H
    New insights into the second generation antihistamines
    DRUGS
    
    G.M. Walsh et al., "New insights into the second generation antihistamines", DRUGS, 61(2), 2001, pp. 207-236
22. Robinson, AJ; Dickenson, JM
    Activation of the p38 and p42/p44 families by the histamine H-1 receptor mitogen-activated protein kinase in DDT1MF-2 cells
    BRITISH JOURNAL OF PHARMACOLOGY
    
    A.J. Robinson e J.M. Dickenson, "Activation of the p38 and p42/p44 families by the histamine H-1 receptor mitogen-activated protein kinase in DDT1MF-2 cells", BR J PHARM, 133(8), 2001, pp. 1378-1386
23. Endou, M; Yanai, K; Sakurai, E; Fukudo, S; Hongo, M; Watanabe, T
    Food-deprived activity stress decreased the activity of the histaminergic neuron system in rats
    BRAIN RESEARCH
    
    M. Endou et al., "Food-deprived activity stress decreased the activity of the histaminergic neuron system in rats", BRAIN RES, 891(1-2), 2001, pp. 32-41
24. Shishoo, CJ; Shirsath, VS; Rathod, IS; Patil, MJ; Bhargava, SS
    Design, synthesis and antihistaminic (H-1) activity of some condensed 2-(substituted) arylaminoethylpyrimidin-4(3H)-ones
    ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH
    
    C.J. Shishoo et al., "Design, synthesis and antihistaminic (H-1) activity of some condensed 2-(substituted) arylaminoethylpyrimidin-4(3H)-ones", ARZNEI-FOR, 51(3), 2001, pp. 221-231
25. Choi, SO; Lee, SH; Kong, HS; Kim, EJ; Choo, HYP
    Stereoselective determination of cetirizine and studies on pharmacokinetics in rat plasma
    JOURNAL OF CHROMATOGRAPHY B
    
    S.O. Choi et al., "Stereoselective determination of cetirizine and studies on pharmacokinetics in rat plasma", J CHROMAT B, 744(1), 2000, pp. 201-206
26. Philpot, EE
    Safety of second generation antihistamines
    ALLERGY AND ASTHMA PROCEEDINGS
    
    E.E. Philpot, "Safety of second generation antihistamines", ALL ASTH P, 21(1), 2000, pp. 15-20
27. Alper, BS
    Choice of antihistamines for urticaria
    ARCHIVES OF FAMILY MEDICINE
    
    B.S. Alper, "Choice of antihistamines for urticaria", ARCH FAM M, 9(8), 2000, pp. 748-751
28. Lorette, G; Giannetti, A; Pereira, RS; Leynadier, F; Murrieta-Aguttes, M
    One-year treatment of chronic urticaria with mizolastine: efficacy and safety
    JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
    
    G. Lorette et al., "One-year treatment of chronic urticaria with mizolastine: efficacy and safety", J EUR A D V, 14(2), 2000, pp. 83-90
29. Simons, FER; Johnston, L; Simons, KJ
    Clinical pharmacology of the H-1-receptor antagonists cetirizine and loratadine in children
    PEDIATRIC ALLERGY AND IMMUNOLOGY
    
    F.E.R. Simons et al., "Clinical pharmacology of the H-1-receptor antagonists cetirizine and loratadine in children", PEDIAT A IM, 11(2), 2000, pp. 116-119
30. Gentile, DA; Friday, GA; Skoner, DP
    Management of allergic rhinitis - Antihistamines and decongestants
    IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA
    
    D.A. Gentile et al., "Management of allergic rhinitis - Antihistamines and decongestants", IMMUNOL ALL, 20(2), 2000, pp. 355
31. Shamsi, Z; Hindmarch, I
    Sedation and antihistamines: A review of inter-drug differences using proportional impairment ratios
    HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL
    
    Z. Shamsi e I. Hindmarch, "Sedation and antihistamines: A review of inter-drug differences using proportional impairment ratios", HUM PSYCHOP, 15, 2000, pp. S3-S30
32. Simons, FER
    Prospective, long-term safety evaluation of the H-1-receptor antagonist cetirizine in very young children with atopic dermatitis
    ALLERGOLOGIE
    
    F.E.R. Simons, "Prospective, long-term safety evaluation of the H-1-receptor antagonist cetirizine in very young children with atopic dermatitis", ALLERGOLOGI, 23(5), 2000, pp. 244-255
33. Pradalier, A; Campinos, C; Barzegar, C; Vincent, D
    Cardiovascular side-effects of antihistamines
    REVUE FRANCAISE D ALLERGOLOGIE ET D IMMUNOLOGIE CLINIQUE
    
    A. Pradalier et al., "Cardiovascular side-effects of antihistamines", REV FR ALLE, 40(3), 2000, pp. 349-354
34. Bindslev-Jensen, C
    Do sedating H-1-antihistamines still have a role to play in the managementof chronic idiopathic urticaria?
    REVUE FRANCAISE D ALLERGOLOGIE ET D IMMUNOLOGIE CLINIQUE
    
    C. Bindslev-Jensen, "Do sedating H-1-antihistamines still have a role to play in the managementof chronic idiopathic urticaria?", REV FR ALLE, 40(1), 2000, pp. 78-81
35. Bousquet, J
    What are the perspectives in the future for H-1-antihistamines?
    REVUE FRANCAISE D ALLERGOLOGIE ET D IMMUNOLOGIE CLINIQUE
    
    J. Bousquet, "What are the perspectives in the future for H-1-antihistamines?", REV FR ALLE, 40(1), 2000, pp. 82-85
36. Kurita, M; Mashiko, H; Ogata, M; Kumasaka, T; Niwa, S; Nakahata, N; Takano, S; Nakanishi, H
    Discrimination of histamine H-1 and muscarinic receptor-mediated signalling pathways by phorbol ester in human astrocytoma cells
    CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
    
    M. Kurita et al., "Discrimination of histamine H-1 and muscarinic receptor-mediated signalling pathways by phorbol ester in human astrocytoma cells", CLIN EXP PH, 27(3), 2000, pp. 208-211
37. Giede, C; Metzenauer, P; Petzold, U; Ellers-Lenz, B
    Comparison of azelastine eye drops with levocabastine eye drops in the treatment of seasonal allergic conjunctivitis
    CURRENT MEDICAL RESEARCH AND OPINION
    
    C. Giede et al., "Comparison of azelastine eye drops with levocabastine eye drops in the treatment of seasonal allergic conjunctivitis", CURR MED R, 16(3), 2000, pp. 153-163
38. Shishoo, CJ; Shirsath, VS; Rathod, IS; Yande, VD
    Design, synthesis and antihistaminic (H-1) activity of some condensed 3-aminopyrimidin-4(3H)-ones
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
    
    C.J. Shishoo et al., "Design, synthesis and antihistaminic (H-1) activity of some condensed 3-aminopyrimidin-4(3H)-ones", EUR J MED C, 35(3), 2000, pp. 351-358
39. Elz, S; Kramer, K; Leschke, C; Schunack, W
    Ring-substituted histaprodifen analogues as partial agonists for histamineH-1 receptors: synthesis and structure-activity relationships
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
    
    S. Elz et al., "Ring-substituted histaprodifen analogues as partial agonists for histamineH-1 receptors: synthesis and structure-activity relationships", EUR J MED C, 35(1), 2000, pp. 41-52
40. Kjaer, A; Knigge, U; Jorgensen, H; Warberg, J
    Dehydration-induced vasopressin secretion in humans: involvement of the histaminergic system
    AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
    
    A. Kjaer et al., "Dehydration-induced vasopressin secretion in humans: involvement of the histaminergic system", AM J P-ENDO, 279(6), 2000, pp. E1305-E1310
41. Mizumura, K; Koda, H; Kumazawa, T
    Possible contribution of protein kinase C in the effects of histamine on the visceral nociceptor activities in vitro
    NEUROSCIENCE RESEARCH
    
    K. Mizumura et al., "Possible contribution of protein kinase C in the effects of histamine on the visceral nociceptor activities in vitro", NEUROSCI RE, 37(3), 2000, pp. 183-190
42. Goren, N; Sterin-Borda, L; Bartrons, R; Gomez, R; Borda, E
    Detection of mRNA encoding H-1 receptor and iNOS by RT-PCR in autoimmune myocarditis with special reference to changes in heart contractility
    INTERNATIONAL JOURNAL OF CARDIOLOGY
    
    N. Goren et al., "Detection of mRNA encoding H-1 receptor and iNOS by RT-PCR in autoimmune myocarditis with special reference to changes in heart contractility", INT J CARD, 76(2-3), 2000, pp. 165-172
43. Yoshida, T; Iwakiri, R; Noda, T; Okamoto, K; Kojima, M; Fukuyama, K; Fujimoto, K
    Histaminergic effect on apoptosis of rat small intestinal mucosa after ischemia-reperfusion
    DIGESTIVE DISEASES AND SCIENCES
    
    T. Yoshida et al., "Histaminergic effect on apoptosis of rat small intestinal mucosa after ischemia-reperfusion", DIG DIS SCI, 45(6), 2000, pp. 1138-1144
44. Sugimoto, Y; Kawamoto, E; Chen, Z; Kamei, C
    A new model of allergic rhinitis in rats by topical sensitization and evaluation of H-1-receptor antagonists
    IMMUNOPHARMACOLOGY
    
    Y. Sugimoto et al., "A new model of allergic rhinitis in rats by topical sensitization and evaluation of H-1-receptor antagonists", IMMUNOPHARM, 48(1), 2000, pp. 1-7
45. Salmun, LM; Gates, D; Scharf, M; Greiding, L; Ramon, F; Heithoff, K
    Loratadine versus cetirizine: Assessment of somnolence and motivation during the workday
    CLINICAL THERAPEUTICS
    
    L.M. Salmun et al., "Loratadine versus cetirizine: Assessment of somnolence and motivation during the workday", CLIN THER, 22(5), 2000, pp. 573-582
46. Abdelaziz, MM; Khair, OA; Devalia, JL
    The potential of active metabolites of antihistamines in the management ofallergic disease
    ALLERGY
    
    M.M. Abdelaziz et al., "The potential of active metabolites of antihistamines in the management ofallergic disease", ALLERGY, 55(5), 2000, pp. 425-434
47. Baroody, FM; Naclerio, RM
    Antiallergic effects of H-1-receptor antagonists
    ALLERGY
    
    F.M. Baroody e R.M. Naclerio, "Antiallergic effects of H-1-receptor antagonists", ALLERGY, 55, 2000, pp. 17-27
48. Timmerman, H
    Factors involved in the absence of sedative effects by the second-generation antihistamines
    ALLERGY
    
    H. Timmerman, "Factors involved in the absence of sedative effects by the second-generation antihistamines", ALLERGY, 55, 2000, pp. 5-10
49. Meltzer, EO; Malmstrom, K; Lu, S; Prenner, BM; Wei, LX; Weinstein, SF; Wolfe, JD; Reiss, TF
    Concomitant montelukast and loratadine as treatment for seasonal allergic rhinitis: A randomized, placebo-controlled clinical trial
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
    
    E.O. Meltzer et al., "Concomitant montelukast and loratadine as treatment for seasonal allergic rhinitis: A randomized, placebo-controlled clinical trial", J ALLERG CL, 105(5), 2000, pp. 917-922
50. Hughes, SACF; Gibson, WJ; Young, JM
    The interaction of U-73122 with the histamine H-1 receptor: implications for the use of U-73122 in defining H-1 receptor-coupled signalling pathways
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
    
    S.A.C.F. Hughes et al., "The interaction of U-73122 with the histamine H-1 receptor: implications for the use of U-73122 in defining H-1 receptor-coupled signalling pathways", N-S ARCH PH, 362(6), 2000, pp. 555-558
51. Franken, C; Trankle, C; Mohr, K
    Testing the specificity of allosteric modulations of muscarinic: receptorsin phylogenetically closely related histamine H-1-receptors
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
    
    C. Franken et al., "Testing the specificity of allosteric modulations of muscarinic: receptorsin phylogenetically closely related histamine H-1-receptors", N-S ARCH PH, 361(2), 2000, pp. 107-112
52. Richelson, E; Souder, T
    Binding of antipsychotic drugs to human brain receptors - Focus on newer generation compounds
    LIFE SCIENCES
    
    E. Richelson e T. Souder, "Binding of antipsychotic drugs to human brain receptors - Focus on newer generation compounds", LIFE SCI, 68(1), 2000, pp. 29-39
53. Singh, N; Puri, SK
    Modulation of halofantrine resistance after coadministration of halofantrine with diverse pharmacological agents in a rodent malaria model
    LIFE SCIENCES
    
    N. Singh e S.K. Puri, "Modulation of halofantrine resistance after coadministration of halofantrine with diverse pharmacological agents in a rodent malaria model", LIFE SCI, 67(11), 2000, pp. 1345-1354
54. Nakazato, E; Yamamoto, T; Ohno, M; Watanabe, S
    Cholinergic and glutamatergic activation reverses working memory failure by hippocampal histamine H-1 receptor blockade in rats
    LIFE SCIENCES
    
    E. Nakazato et al., "Cholinergic and glutamatergic activation reverses working memory failure by hippocampal histamine H-1 receptor blockade in rats", LIFE SCI, 67(10), 2000, pp. 1139-1147
55. Hishinuma, S; Ogura, K
    Ca2+/calmodulin-mediated regulation of the desensitizing process in G(q) protein-coupled histamine H-1 receptor-mediated Ca2+ responses in human U373MG astrocytoma cells
    JOURNAL OF NEUROCHEMISTRY
    
    S. Hishinuma e K. Ogura, "Ca2+/calmodulin-mediated regulation of the desensitizing process in G(q) protein-coupled histamine H-1 receptor-mediated Ca2+ responses in human U373MG astrocytoma cells", J NEUROCHEM, 75(2), 2000, pp. 772-781
56. Elz, S; Kramer, K; Pertz, HH; Detert, H; ter Laak, AM; Kuhne, R; Schunack, W
    Histaprodifens: Synthesis, pharmacological in vitro evaluation, and molecular modeling of a new class of highly active and selective histamine H-1-receptor agonists
    JOURNAL OF MEDICINAL CHEMISTRY
    
    S. Elz et al., "Histaprodifens: Synthesis, pharmacological in vitro evaluation, and molecular modeling of a new class of highly active and selective histamine H-1-receptor agonists", J MED CHEM, 43(6), 2000, pp. 1071-1084
57. Crivori, P; Cruciani, G; Carrupt, PA; Testa, B
    Predicting blood-brain barrier permeation from three-dimensional molecularstructure
    JOURNAL OF MEDICINAL CHEMISTRY
    
    P. Crivori et al., "Predicting blood-brain barrier permeation from three-dimensional molecularstructure", J MED CHEM, 43(11), 2000, pp. 2204-2216
58. Walczynski, K; Guryn, R; Zuiderveld, OP; Zhang, MQ; Timmerman, H
    Histamine H-1 receptor ligands Part II. Synthesis and in vitro pharmacology of 2-[2-(phenylamino)thiazol-4-yl]ethanamine and 2-(2-benzhydrylthiazol-4-yl)ethanamine derivatives
    FARMACO
    
    K. Walczynski et al., "Histamine H-1 receptor ligands Part II. Synthesis and in vitro pharmacology of 2-[2-(phenylamino)thiazol-4-yl]ethanamine and 2-(2-benzhydrylthiazol-4-yl)ethanamine derivatives", FARMACO, 55(9-10), 2000, pp. 569-574
59. Inagaki, N; Nagao, M; Nakamura, N; Kawasaki, H; Igeta, K; Musoh, K; Nagai, H
    Evaluation of anti-scratch properties of oxatomide and epinastine in mice
    EUROPEAN JOURNAL OF PHARMACOLOGY
    
    N. Inagaki et al., "Evaluation of anti-scratch properties of oxatomide and epinastine in mice", EUR J PHARM, 400(1), 2000, pp. 73-79
60. Mobarakeh, JI; Sakurada, S; Katsuyama, S; Kutsuwa, M; Kuramasu, A; Lin, ZY; Watanabe, T; Hashimoto, Y; Watanabe, T; Yanai, K
    Of histamine H-1 receptor in pain perception: a study of the receptor geneknockout mice
    EUROPEAN JOURNAL OF PHARMACOLOGY
    
    J.I. Mobarakeh et al., "Of histamine H-1 receptor in pain perception: a study of the receptor geneknockout mice", EUR J PHARM, 391(1-2), 2000, pp. 81-89
61. Bakker, RA; Wieland, K; Timmerman, H; Leurs, R
    Constitutive activity of the histamine H-1 receptor reveals inverse agonism of histamine H-1 receptor antagonists
    EUROPEAN JOURNAL OF PHARMACOLOGY
    
    R.A. Bakker et al., "Constitutive activity of the histamine H-1 receptor reveals inverse agonism of histamine H-1 receptor antagonists", EUR J PHARM, 387(1), 2000, pp. R5-R7
62. Hurst, M; Spencer, CM
    Ebastine - An update of its use in allergic disorders
    DRUGS
    
    M. Hurst e C.M. Spencer, "Ebastine - An update of its use in allergic disorders", DRUGS, 59(4), 2000, pp. 981-1006
63. Hamelin, BA; Bouayad, A; Methot, J; Jobin, J; Desgagnes, P; Poirier, P; Allaire, J; Dumesnil, J; Turgeon, J
    Significant interaction between the nonprescription antihistamine diphenhydramine and the CYP2D6 substrate metoprolol in healthy men with high or lowCYP2D6 activity
    CLINICAL PHARMACOLOGY & THERAPEUTICS
    
    B.A. Hamelin et al., "Significant interaction between the nonprescription antihistamine diphenhydramine and the CYP2D6 substrate metoprolol in healthy men with high or lowCYP2D6 activity", CLIN PHARM, 67(5), 2000, pp. 466-477
64. Gilbert, JD; Cahill, SA; McCartney, DG; Lukas, A; Gross, GJ
    Predictors of Torsades de Pointes in rabbit ventricles perfused with sedating and nonsedating histamine H-1-receptor antagonists
    CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
    
    J.D. Gilbert et al., "Predictors of Torsades de Pointes in rabbit ventricles perfused with sedating and nonsedating histamine H-1-receptor antagonists", CAN J PHYSL, 78(5), 2000, pp. 407-414
65. Taglialatela, M; Pannaccione, A; Castaldo, P; Giorgio, G; Annunziato, L
    Inhibition of HERG1 K+ channels by the novel second-generation antihistamine mizolastine
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66. Chambers, RJ; Marfat, A
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81. Hindmarch, I; Shamsi, Z
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89. Kubota, Y; Ito, C; Kuramasu, A; Sato, M; Watanabe, T
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93. Segarra, V; Lopez, M; Ryder, H; Palacios, JM; Roberts, DJ
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95. Simons, FER
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96. Sussman, GL; Mason, J; Compton, D; Stewart, J; Ricard, N
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97. Corren, J; Rachelefsky, G; Spector, S; Schanker, H; Siegel, S; Holton, D; Karcher, K; Travers, S
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98. Simons, FER; Roberts, JR; Gu, XC; Kapur, S; Simons, KJ
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99. Rossi, R; Del Prete, E; Scharrer, E
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100. Malinowska, B; Piszcz, J; Schlicker, E; Kramer, K; Elz, S; Schunack, W
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