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An automatic 96-well solid phase extraction and liquid chromatography-tandem mass spectrometry method for the analysis of morphine, morphine-3-glucuronide and morphine-6-glucuronide in human plasma
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
Morphine-6 beta-glucuronide induces potent immunomodulation
INTERNATIONAL IMMUNOPHARMACOLOGY
Ultrasound and endocrine evaluation of the ovarian cycle and early pregnancy in the Sumatran rhinoceros, Dicerorhinus sumatrensis
REPRODUCTION
Identification of morphine and morphine-6-glucuronide in the adrenal medullary chromaffin PC-12 cell line by nano-electrospray ionization double quadrupole orthogonal-acceleration time-of-flight mass spectrometry
EUROPEAN JOURNAL OF MASS SPECTROMETRY
Direct chiral assay of tramadol and detection of the phase II metabolite O-demethyl tramadol glucuronide in human urine using capillary electrophoresis with laser-induced native fluorescence detection
JOURNAL OF CHROMATOGRAPHY B
Determination of mycophenolic acid and its phenol glucuronide metabolite in human plasma and urine by high-performance liquid chromatography
JOURNAL OF CHROMATOGRAPHY B
High-performance liquid chromatographic assay for abacavir and its two major metabolites in human urine and cerebrospinal fluid
JOURNAL OF CHROMATOGRAPHY B
Validated methods for direct determination of hydroquinone glucuronide andsulfate in human urine after oral intake of bearberry leaf extract by capillary zone electrophoresis
JOURNAL OF CHROMATOGRAPHY B
Methodology for the development of a drug library based upon collision-induced fragmentation for the identification of toxicologically relevant drugsin plasma samples
JOURNAL OF CHROMATOGRAPHY B
Quantitation of entacapone glucuronide in rat plasma by on-line coupled restricted access media column and liquid chromatography-tandem mass spectrometry
JOURNAL OF CHROMATOGRAPHY B
Metabolism of bucolome in rats - Stability and biliary excretion of bucolome N-glucuronide
JOURNAL OF CHROMATOGRAPHY B
Improvement of ethyl glucuronide determination in human urine and serum samples by solid-phase extraction
JOURNAL OF CHROMATOGRAPHY B
Synthesis, high-performance liquid chromatography-nuclear magnetic resonance characterization and pharmacokinetics in mice of CD271 glucuronide
JOURNAL OF CHROMATOGRAPHY B
Quantification of mycophenolate mofetil in human skin extracts using high-performance liquid chromatography-electrospray mass spectrometry
JOURNAL OF CHROMATOGRAPHY B
Simultaneous determination of buprenorphine, norbuprenorphine, and buprenorphine-glucuronide in plasma by liquid chromatography-tandem mass spectrometry
JOURNAL OF CHROMATOGRAPHY B
Identification of quercetin glucuronides in human plasma by high-performance liquid chromatography-tandem mass spectrometry
JOURNAL OF CHROMATOGRAPHY B
High-performance liquid chromatographic assay for acetaminophen glucuronide in human liver microsomes
JOURNAL OF CHROMATOGRAPHY B
Rapid and simultaneous determination of mycophenolic acid and its glucuronide conjugate in human plasma by ion-pair reversed-phase high-performance liquid chromatography using isocratic elution
JOURNAL OF CHROMATOGRAPHY B
Quantification of urine 17-ketosteroid sulfates and glucuronides by high-performance liquid chromatography-ion trap mass spectroscopy
JOURNAL OF CHROMATOGRAPHY B
Liquid chromatographic assay for simultaneous determination of abacavir and mycophenolic acid in human plasma using dual spectrophotometric detection
JOURNAL OF CHROMATOGRAPHY B
Biliary excretion of phenolphthalein glucuronide in the rat
HEPATOLOGY RESEARCH
The role of metabolism and toxicokinetics in retinoid teratogenesis
CURRENT PHARMACEUTICAL DESIGN
High urine 1-hydroxypyrene glucuronide concentrations in Linxian, China, an area of high risk for squamous oesophageal cancer
BIOMARKERS
Presence of endogenous morphine and morphine 6 glucuronide in human heart tissue
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
Characterization of rat and human UDP-glucuronosyltransferases responsiblefor the in vitro glucuronidation of diclofenac
TOXICOLOGICAL SCIENCES
Clinical implications of rhinoceros reproductive tract anatomy and histology
JOURNAL OF ZOO AND WILDLIFE MEDICINE
Voltammetry of coumarins
ELECTROANALYSIS
The synthesis of the glucuronide metabolite of UK-157,147 using immobilised uridine 5 '-diphosphoglucuronyl transferase and traditional organic chemistry techniques (imidate method)
BIOCATALYSIS AND BIOTRANSFORMATION
Metabolism and biliary excretion of the novel anticancer agent 10-hydroxycamptothecin in the isolated perfused rat liver
INTERNATIONAL JOURNAL OF ONCOLOGY
Application of photoaffinity labeling with [H-3] all trans- and 9-cis-retinoic acids for characterization of cellular retinoic acid-binding proteins I and II
PROTEIN SCIENCE
An unhydrolyzable analogue of N-(4-hydroxyphenyl)retinamide: Synthesis andpreliminary biological studies
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Hydro phobic forms of morphine 6-glucosides
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Use of on-line hydrogen/deuterium exchange to facilitate metabolite identification
RAPID COMMUNICATIONS IN MASS SPECTROMETRY
Anticancer prodrugs for application in monotherapy: Targeting hypoxia, tumor-associated enzymes, and receptors
CURRENT MEDICINAL CHEMISTRY
Glycosides in medicine: "The role of glycosidic residue in biological activity"
CURRENT MEDICINAL CHEMISTRY
Effect of pH on metabolism of glycyrrhizin, glycyrrhetic acid and glycyrrhetic acid monoglucuronide by collected human intestinal flora
BIOLOGICAL & PHARMACEUTICAL BULLETIN
Simultaneous determination of glycyrrhizin, glycyrrhetic acid and glycyrrhetic acid mono-glucuronide in Shakuyaku-kanzo-to incubated with rat feces by semi-micro high-performance liquid chromatography
BIOLOGICAL & PHARMACEUTICAL BULLETIN
Derivative matrix isopotential synchronous fluorescence spectroscopy for the direct determination of 1-hydroxypyrene as a urinary biomarker of exposure to polycyclic aromatic hydrocarbons
ANALYTICAL SCIENCES
Puberty and prognosis of asthma and bronchial hyper-reactivity
PEDIATRIC ALLERGY AND IMMUNOLOGY
HPLC/H-1 NMR spectroscopic studies of the reactive alpha-1-O-acyl isomer formed during acyl migration of S-naproxen beta-1-O-acyl glucuronide
CHEMICAL RESEARCH IN TOXICOLOGY
Contrasting influences of glucuronidation and O-methylation of epicatechinon hydrogen peroxide-induced cell death in neurons and fibroblasts
FREE RADICAL BIOLOGY AND MEDICINE
Identification of quercetin 3-O-beta-D-glucuronide as an antioxidative metabolite in rat plasma after oral administration of quercetin
FREE RADICAL BIOLOGY AND MEDICINE
Opioid poorly-responsive cancer pain. Part 1: Clinical considerations
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
Contemporary drug therapy in palliative care: New directions
CANCER INVESTIGATION
Switching from morphine to methadone to improve analgesia and tolerabilityin cancer patients: A prospective study
JOURNAL OF CLINICAL ONCOLOGY
LC determination of morphine and morphine glucuronides in human plasma by coulometric and UV detection
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
Determination of UDP-glucuronosyltransferase UGT1A6 activity in human and rat liver microsomes by HPLC with UV detection
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
Rapid and simple determination of mycophenolic acid in human plasma by ion-pair RP-LC with fluorescence detection
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
LC-H-1 NMR used for determination of the elution order of S-naproxen glucuronide isomers in two isocratic reversed-phase LC-systems
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
Colonic drug delivery: Prodrug approach
PHARMACEUTICAL RESEARCH
Functional hyperandrogenism detected by corticotropin and GnRH-analogue stimulation tests in women affected by apparently idiopathic hirsutism
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
Characterisation of glucuronidation and transport in V79 cells co-expressing UGT1A1 and MRP1
TOXICOLOGY LETTERS
Agonists determine the pattern of G-protein activation in mu-opioid receptor-mediated supraspinal analgesia
BRAIN RESEARCH BULLETIN
Morphine-6 beta-glucuronide modulates the expression of inducible nitric oxide synthase
INFLAMMATION
Effects of the serotonin receptor antagonist cyproheptadine on the activity and pharmacokinetics of 5,6-dimethylxanthenone-4-acetic acid (DMXAA)
CANCER CHEMOTHERAPY AND PHARMACOLOGY
Effects of all-trans-retinoic acid and all-trans-retinoyl glucuronide in two in vitro systems of distinct biological complexity
ARCHIVES OF TOXICOLOGY
Morphine-6-glucuronide - An analgesic of the future?
CLINICAL PHARMACOKINETICS
Lack of effect of ondansetron on the pharmacokinetics and analgesic effects of morphine and metabolites after single-dose morphine administration in healthy volunteers
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
Potential fertility - Defining the window of opportunity
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
Home monitoring with the ClearPlan Easy (TM) fertility monitor for fertility awareness
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
Changes of urinary steroid conjugates and gonadotropin excretion in the menstrual cycle and pregnancy in the Yunnan snub-nosed monkey (Rhinopithecus bieti)
AMERICAN JOURNAL OF PRIMATOLOGY
Retrospective study of the use of hydromorphone in palliative care patients with normal and abnormal urea and creatinine
PALLIATIVE MEDICINE
Efficacy of the combination ethinyl oestradiol and cyproterone acetate on endocrine, clinical and ultrasonographic profile in polycystic ovarian syndrome
HUMAN REPRODUCTION
Palliative pain therapy at the end of life and forensic medicine issues
AMERICAN JOURNAL OF FORENSIC MEDICINE AND PATHOLOGY
An integrated H-2 and C-13 NMR study of gluconeogenesis and TCA cycle fluxin humans
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
Presence of morphine and morphine-6-glucuronide in the marine mollusk Mytilus edulis ganglia determined by GC/MS and Q-TOF-MS - Starvation increases opiate alkaloid levels
MOLECULAR BRAIN RESEARCH
Detection of hormone mimics in water using a miniturised SPR sensor
ENVIRONMENTAL MONITORING AND ASSESSMENT
Uptake, metabolism and excretion of bisphenol A in the rainbow trout (Oncorhynchus mykiss)
AQUATIC TOXICOLOGY
Diabetic macular edema: Passive and active transport of fluorescein through the blood-retina barrier
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
Strong opioids for cancer pain
JOURNAL OF THE ROYAL SOCIETY OF MEDICINE
In vitro enzymic synthesis of mammalian liver xenobiotic metabolites catalysed by ovine liver microsomal cytochrome P-450
ENZYME AND MICROBIAL TECHNOLOGY
Identification and cloning of gusA, encoding a new beta-glucuronidase fromLactobacillus gasseri ADH
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
Pharmacokinetics of tilidine in terminal renal failure
JOURNAL OF CLINICAL PHARMACOLOGY
Mechanism-based inactivation of CYP2C11 by diclofenac
DRUG METABOLISM AND DISPOSITION
Isolation and identification of clozapine metabolites in patient urine
DRUG METABOLISM AND DISPOSITION
S-naproxen-ss-1-O-acyl glucuronide degradation kinetic studies by stopped-flow high-performance liquid chromatography-H-1 NMR and high-performance liquid chromatography-UV
DRUG METABOLISM AND DISPOSITION
In vivo perturbation of rat hepatocyte canalicular membrane function by diclofenac
DRUG METABOLISM AND DISPOSITION
Monitoring of mycophenolic acid in pediatric renal transplant recipients
TRANSPLANTATION PROCEEDINGS
Selective synthesis of both isomers of morphine 6-beta-D-glucuronide and their analogs
TETRAHEDRON
First finding of Daidzein 7-O-phosphate and Genistein 7-O-phosphate that are hydrolyzed by sulfatase
TETRAHEDRON
Biliary excretion of tauroursodeoxycholate-3-sulfate in the rat
STEROIDS
Glycosides and xanthine oxidase inhibitors from Conyza bonariensis
PHYTOCHEMISTRY
The ABC-like vacuolar transporter for rye mesophyll flavone glucuronides is not species-specific
PHYTOCHEMISTRY
Bioactive oleanolic acid saponins and other constituents from the roots ofViguiera decurrens
PHYTOCHEMISTRY
Wheel running attenuates the antinociceptive properties of morphine and its metabolite, morphine-6-glucuronide, in rats
PHYSIOLOGY & BEHAVIOR
Pharmacokinetics of morphine 3-esters after oral administration in rabbits
PHARMAZIE
Chemistry of uncondensed 1,2,4-triazines, part IV - Synthesis and chemistry of bioactive 3-amino-1,2,4-triazines and related compounds - an overview
PHARMAZIE
Rearrangement of diflunisal acyl glucuronide into its beta-glucuronidase-resistant isomers facilitates transport through the small intestine to the colon of the rat
LIFE SCIENCES
Hydromorphone-3-glucuronide - A more potent neuro-excitant than its structural analogue, morphine-3-glucuronide
LIFE SCIENCES
Dipeptidyl peptidase IV is a target for covalent adduct formation with theacyl glucuronide metabolite of the anti-inflammatory drug zomepirac
LIFE SCIENCES
Insights into mu opioid pharmacology - The role of mu opioid receptor subtypes
LIFE SCIENCES
Discriminative stimulus effects of intravenous heroin and its metabolites in rhesus monkeys: Opioid and dopaminergic mechanisms
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
Probenecid-associated alterations in valproate glucuronide hepatobiliary disposition: Mechanistic assessment using mathematical modeling
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
Sex-related differences in antinociception and tolerance development following chronic intravenous infusion of morphine in the rat: Modulatory role of testosterone via morphine clearance
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
Pharmacokinetic and pharmacodynamic evaluations of a potent analgesic, dihydroetorphine, in hairless rat
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
Limited phase I study of morphine-3-glucuronide
JOURNAL OF PHARMACEUTICAL SCIENCES
Postmortem blood free and total morphine concentrations in medical examiner cases
JOURNAL OF FORENSIC SCIENCES
Comparison of the rates of hydrolysis of lorazepam-glucuronide, oxazepam-glucuronide and temazepam-glucuronide catalyzed by E-coli, beta-D-glucuronidase using the on-line benzodiazepine screening immunoassay on the Roche/Hitachi 917 analyzer
JOURNAL OF FORENSIC SCIENCES
Rapid and specific detection of hydroxyl radical using an ultraweak chemiluminescence analyzer and a low-level chemiluminescence emitter: Applicationto hydroxyl radical-scavenging ability of aqueous extracts of food constituents
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Inhibitory effect of a quercetin metabolite, quercetin 3-O-beta-D-glucuronide, on lipid peroxidation in liposomal membranes
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY