Catalogo Articoli (Spogli Riviste)

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    1. Braun, B; Rock, PB; Zamudio, S; Wolfel, GE; Mazzeo, RS; Muza, SR; Fulco, CS; Moore, LG; Butterfield, GE
      Women at altitude: short-term exposure to hypoxia and/or alpha(1)-adrenergic blockade reduces insulin sensitivity

      JOURNAL OF APPLIED PHYSIOLOGY
    2. Ryan, AS; Muller, DC; Elahi, D
      Sequential hyperglycemic-euglycemic clamp to assess beta-cell and peripheral tissue: studies in female athletes

      JOURNAL OF APPLIED PHYSIOLOGY
    3. Saengsirisuwan, V; Kinnick, TR; Schmit, MB; Henriksen, EJ
      Interactions of exercise training and lipoic acid on skeletal muscle glucose transport in obese Zucker rats

      JOURNAL OF APPLIED PHYSIOLOGY
    4. Latour, MG; Shinoda, M; Lavoie, JM
      Metabolic effects of physical training in ovariectomized and hyperestrogenic rats

      JOURNAL OF APPLIED PHYSIOLOGY
    5. Rush, D
      Maternal nutrition and perinatal survival

      JOURNAL OF HEALTH POPULATION AND NUTRITION
    6. Abadie, JM; Malcom, GT; Porter, JR; Svec, F
      Dehydroepiandrosterone alters Zucker rat soleus and cardiac muscle lipid profiles

      EXPERIMENTAL BIOLOGY AND MEDICINE
    7. Ho, E; Quan, N; Tsai, YH; Lai, WM; Bray, TM
      Dietary zinc supplementation inhibits NF kappa B activation and protects against chemically induced diabetes in CD1 mice

      EXPERIMENTAL BIOLOGY AND MEDICINE
    8. Simon, SF; Taylor, CG
      Dietary zinc supplementation attenuates hyperglycemia in db/db mice

      EXPERIMENTAL BIOLOGY AND MEDICINE
    9. Johansen, T; Hansen, HS; Richelsen, B; Malmlof, K
      The obese Gottingen minipig as a model of the metabolic syndrome: Dietary effects on obesity, insulin sensitivity, and growth hormone profile

      COMPARATIVE MEDICINE
    10. Carr, CA
      Evidence-based diabetes screening during pregnancy

      JOURNAL OF MIDWIFERY & WOMENS HEALTH
    11. Dube, MP; Edmondson-Melancon, H; Qian, D; Aqeel, R; Johnson, D; Buchanan, TA
      Prospective evaluation of the effect of initiating indinavir-based therapyon insulin sensitivity and B-cell function in HIV-infected patients

      JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
    12. Gloyn, AL; McCarthy, MI
      The genetics of type 2 diabetes

      BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
    13. Shapiro, AMJ; Ryan, EA; Lakey, JRT
      Pancreatic islet transplantation in the treatment of diabetes mellitus

      BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
    14. Flechtner-Mors, M; Jenkinson, CP; Alt, A; Adler, G; Ditschuneit, HH
      Effects of acipimox on the lipolysis rate in subcutaneous adipose tissue of obese subjects

      DIABETES-METABOLISM RESEARCH AND REVIEWS
    15. Hanson, RL; Imperatore, G; Narayan, KMV; Roumain, J; Fagot-Campagna, A; Pettitt, DJ; Bennett, PH; Knowler, WC
      Family and genetic studies of indices of insulin sensitivity and insulin secretion in Pima Indians

      DIABETES-METABOLISM RESEARCH AND REVIEWS
    16. Taylor, WH; Khaleeli, AA
      Coincident diabetes mellitus and primary hyperparathyroidism

      DIABETES-METABOLISM RESEARCH AND REVIEWS
    17. Rosen, P; Nawroth, PP; King, G; Moller, W; Tritschler, HJ; Packer, L
      The role of oxidative stress in the onset and progression of diabetes and its complications: a summary of a Congress Series sponsored by UNESCO-MCBN,the American Diabetes Association and the German Diabetes Society

      DIABETES-METABOLISM RESEARCH AND REVIEWS
    18. Mayer-Davis, EJ; Levin, S; Bergman, RN; D'Agostino, RB; Karter, AJ; Saad, MF
      Insulin secretion, obesity, and potential behavioral influences: results from the Insulin Resistance Atherosclerosis Study (IRAS)

      DIABETES-METABOLISM RESEARCH AND REVIEWS
    19. Barbieri, M; Rizzo, MR; Manzella, D; Paolisso, G
      Age-related insulin resistance: is it an obligatory finding? The Lesson from healthy centenarians

      DIABETES-METABOLISM RESEARCH AND REVIEWS
    20. Kousta, E; Lawrence, NJ; Anyaoku, V; Johnston, DG; McCarthy, MI
      Prevalence and features of pancreatic islet cell autoimmunity in women with gestational diabetes from different ethnic groups

      BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY
    21. Wang, J; Cheung, AT; Kolls, JK; Starks, WW; Martinez-Hernandez, A; Dietzen, D; Bryer-Ash, M
      Effects of adenovirus-mediated liver-selective overexpression of protein tyrosine phosphatase-1b on insulin sensitivity in vivo

      DIABETES OBESITY & METABOLISM
    22. van-Dybicz, AMO; Vonkeman, HE; Bon, MAM; van den Bergh, FAJTM; Vermes, I
      beta(3)-Adrenergic receptor gene polymorphism and type 2 diabetes in a Caucasian population

      DIABETES OBESITY & METABOLISM
    23. Finegood, DT; Topp, BG
      beta-cell deterioration - prospects for reversal or prevention

      DIABETES OBESITY & METABOLISM
    24. Drucker, DJ
      Development of glucagon-like peptide-1-based pharmaceuticals as therapeutic agents for the treatment of diabetes

      CURRENT PHARMACEUTICAL DESIGN
    25. Riese, H; Vrijkotte, TGM; Meijer, P; Kluft, C; De Geus, EJC
      Covariance of metabolic and hemostatic risk indicators in men and women

      FIBRINOLYSIS & PROTEOLYSIS
    26. Kahn, SE
      Beta cell failure: causes and consequences

      INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
    27. Laakso, M
      Insulin resistance and its impact on the approach to therapy of Type 2 diabetes

      INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
    28. Shahmanesh, M; Jaleel, H; DeSilva, Y; Ross, JDC; Caslake, M; Cramb, R
      Protease inhibitor related type III hyperlipoproteinaemia is common and not associated with apolipoprotein-E E2/E2 phenotype

      SEXUALLY TRANSMITTED INFECTIONS
    29. Liu, J; Zhang, B; He, X; Zhang, P; Chai, Z
      Selection of a high-biomass, chromium-rich yeast strain and optimization of cultivation conditions

      JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
    30. Gill, GV; Scott, B; Beeching, NJ; Wilkinson, D; Ismail, AA
      Enumeration of non-communicable disease in rural South Africa by electronic data linkage and capture-recapture techniques

      TROPICAL MEDICINE & INTERNATIONAL HEALTH
    31. Lien, TF; Wu, CP; Wang, BJ; Shiao, MS; Shiao, TY; Lin, BH; Lu, JJ; Hu, CY
      Effect of supplemental levels of chromium picolinate on the growth performance, serum traits, carcass characteristics and lipid metabolism of growing-finishing pigs

      ANIMAL SCIENCE
    32. Okosun, IS
      Racial differences in rates of type 2 diabetes in American women: how muchis due to differences in overall adiposity?

      ETHNICITY & HEALTH
    33. Chaturvedi, N; McKeigue, PM; Marmot, MG; Nihoyannopoulos, P
      A comparison of left ventricular abnormalities associated with glucose intolerance in African Caribbeans and Europeans in the UK

      HEART
    34. Crosignani, PG; Nicolosi, AE
      Polycystic ovarian disease: heritability and heterogeneity

      HUMAN REPRODUCTION UPDATE
    35. Moghetti, P
      Advances in the treatment of polycystic ovary syndrome

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    36. Ducluzeau, PH; Laville, M; Vidal, H; Pugeat, M
      Polycystic ovary syndrome and insulin resistance

      DIABETES & METABOLISM
    37. Vambergue, A
      Managing gestational diabetes in 2001

      DIABETES & METABOLISM
    38. Custro, N; Carroccio, A; Ganci, A; Scafidi, V; Campagna, P; Di Prima, L; Montalto, G
      Glycemic homeostasis in chronic viral hepatitis and liver cirrhosis

      DIABETES & METABOLISM
    39. Chihaoui, M; Kanoun, F; Ben Rehaiem, B; Ben Brahim, S; Ftouhi, B; Mekaouar, A; Fekih, M; Mbazad, A; Zouari, B; Ben Khalifa, F
      Predictive risk factors for deterioration from normoglycemic state to type2 diabetes mellitus or impaired glucose tolerance in a Tunisian urban population

      DIABETES & METABOLISM
    40. Rabasa-Lhoret, R; Laville, M
      How to measure insulin sensitivity in clinical practice?

      DIABETES & METABOLISM
    41. Despres, JP; Lemieux, I; Tchernof, A; Couillard, C; Pascot, A; Lemieux, S
      Fat distribution and metabolism

      DIABETES & METABOLISM
    42. Buysschaert, M; Vandenbroucke, C; Barsoum, S
      A type 2 diabetes screening program by general practioners in a Belgian atrisk population

      DIABETES & METABOLISM
    43. Guerrero-Romero, F; Rodriguez-Moran, M
      Glucose intolerance is predicted by the high fasting insulin-to-glucose ratio

      DIABETES & METABOLISM
    44. Turnin, MC; Bourgeois, O; Cathelineau, G; Leguerrier, AM; Halimi, S; Sandre-Banon, D; Coliche, V; Breux, M; Verlet, E; Labrousse, F; Bensoussan, D; Grenier, JL; Poncet, MF; Tordjmann, F; Brun, JM; Blickle, JF; Mattei, C; Bolzonella, C; Buisson, JC; Fabre, D; Tauber, JP; Hanaire-Broutin, H
      Multicenter randomized evaluation of a nutritional education software in obese patients

      DIABETES & METABOLISM
    45. Krejpcio, Z
      Essentiality of chromium for human nutrition and health

      POLISH JOURNAL OF ENVIRONMENTAL STUDIES
    46. Visseren, FLJ; Bouter, PK; van Loon, BJP; Erkelens, WD
      Treatment of dyslipidaemia with fluvastatin in patients with type 2 diabetes mellitus - Effects on lipids, mental state and fibrinolysis

      CLINICAL DRUG INVESTIGATION
    47. St-Pierre, J; Vohl, MC; Brisson, D; Perron, P; Despres, JP; Hudson, TJ; Gaudet, D
      A sequence variation in the mitochondrial glycerol-3-phosphate dehydrogenase gene is associated with increased plasma glycerol and free fatty acid concentrations among French Canadians

      MOLECULAR GENETICS AND METABOLISM
    48. Duhlmeier, R; Deegen, E; Fuhrmann, H; Widdel, A; Sallmann, HP
      Glucose-dependent insulinotropic polypeptide (GIP) and the enteroinsular axis in equines (Equus caballus)

      COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR AND INTEGRATIVE PHYSIOLOGY
    49. Strutton, DR; Stang, PE; Erbey, JR; Lydick, E
      Estimated coronary heart disease attributable to insulin resistance in populations with and without type 2 diabetes mellitus

      AMERICAN JOURNAL OF MANAGED CARE
    50. Kareinen, A; Viitanen, L; Halonen, P; Lehto, S; Laakso, M
      Cardiovascular risk factors associated with insulin resistance cluster in families with early-onset coronary heart disease

      ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
    51. Purnell, JQ; Kahn, SE; Schwartz, RS; Brunzell, JD
      Relationship of insulin sensitivity and ApoB levels to intra-abdominal fatin subjects with familial combined hyperlipidemia

      ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
    52. Korosi, J; McIntosh, CHS; Pederson, RA; Demuth, HU; Habener, JF; Gingerich, R; Egan, JM; Elahi, D; Meneilly, GS
      Effect of aging and diabetes on the enteroinsular axis

      JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
    53. Arias, EB; Gosselin, LE; Cartee, GD
      Exercise training eliminates age-related differences in skeletal muscle insulin receptor and IRS-1 abundance in rats

      JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
    54. Meneilly, GS; Tessier, D
      Diabetes in elderly adults

      JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
    55. Resnick, HE; Vinik, AI; Heimovitz, HK; Brancati, FL; Guralnik, JM
      Age 85+years accelerates large-fiber peripheral nerve dysfunction and diabetes contributes even in the oldest-old: The Women's Health and Aging Study

      JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
    56. Zanobetti, A; Schwartz, J
      Are diabetics more susceptible to the health effects of airborne particles?

      AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    57. Teixeira, PJ; Sardinha, LB; Going, SB; Lohman, TG
      Total and regional fat and serum cardiovascular disease risk factors in lean and obese children and adolescents

      OBESITY RESEARCH
    58. Berthier, MT; Couillard, C; Prud'homme, D; Nadeau, A; Bergeron, J; Tremblay, A; Despres, JP; Vohl, MC
      Effects of the FABP2 A54T mutation on triglyceride metabolism of viscerally obese men

      OBESITY RESEARCH
    59. Iwao, S; Iwao, N; Muller, DC; Elahi, D; Shimokata, H; Andres, R
      Does waist circumference add to the predictive power of the body mass index for coronary risk?

      OBESITY RESEARCH
    60. Rubies-Prat, J; Ordonez-Llanos, J; Martin, S; Blanco-Vaca, F; Molina, L; Goday, A; Pedro-Botet, J
      Low-density lipoprotein particle size, triglyceride-rich lipoproteins, andglucose tolerance in non-diabetic men with essential hypertension

      CLINICAL AND EXPERIMENTAL HYPERTENSION
    61. Owada, A; Suda, S; Hata, T; Miyake, S
      The effects of bisoprolol, a selective beta(1)-blocker, on glucose metabolism by long-term administration in essential hypertension

      CLINICAL AND EXPERIMENTAL HYPERTENSION
    62. Culleton, BF
      Uric acid and cardiovascular disease: a renal-cardiac relationship?

      CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION
    63. Hughes, CA; Taylor, GD
      Metformin in an HIV-infected patient with protease inhibitor-induced diabetic ketoacidosis

      ANNALS OF PHARMACOTHERAPY
    64. Avram, AM; Patel, V; Taylor, HC; Kirwan, JP; Kalhan, S
      Euglycemic clamp study in clozapine-induced diabetic ketoacidosis

      ANNALS OF PHARMACOTHERAPY
    65. Hadigan, C; Jeste, S; Anderson, EJ; Tsay, R; Cyr, H; Grinspoon, S
      Modifiable dietary habits and their relation to metabolic abnormalities inmen and women with human immunodeficiency virus infection and fat redistribution

      CLINICAL INFECTIOUS DISEASES
    66. Hadigan, C; Meigs, JB; Corcoran, C; Rietschel, P; Piecuch, S; Basgoz, N; Davis, B; Sax, P; Stanley, T; Wilson, PWF; D'Agostino, RB; Grinspoon, S
      Metabolic abnormalities and cardiovascular disease risk factors in adults with human immunodeficiency virus infection and lipodystrophy

      CLINICAL INFECTIOUS DISEASES
    67. Abate, N; Chandalia, M
      Ethnicity and type 2 diabetes - Focus on Asian Indians

      JOURNAL OF DIABETES AND ITS COMPLICATIONS
    68. Papadakis, JA; Milionis, HJ; Press, M; Mikhailidis, DP
      Treating dyslipidaemia in non-insulin-dependent diabetes mellitus - a special reference to statins

      JOURNAL OF DIABETES AND ITS COMPLICATIONS
    69. Guerrero-Romero, F; Rodriguez-Moran, M
      Impaired glucose tolerance is a more advanced stage of alteration in the glucose metabolism than impaired fasting glucose

      JOURNAL OF DIABETES AND ITS COMPLICATIONS
    70. Nieuwenhuis, MG; Kirkels, JH
      Predictability and other aspects of post-transplant diabetes mellitus in heart transplant recipients

      JOURNAL OF HEART AND LUNG TRANSPLANTATION
    71. Fulton-Kehoe, B; Hamman, RF; Baxter, J; Marshall, J
      A case-control study of physical activity and non-insulin dependent diabetes mellitus (NIDDM): The San Luis Valley Diabetes Study

      ANNALS OF EPIDEMIOLOGY
    72. Rotimi, CN; Dunston, GM; Berg, K; Akinsete, O; Amoah, A; Owusu, S; Acheampong, J; Boateng, K; Oli, J; Okafor, G; Onyenekwe, B; Osotimehin, B; Abbiyesuku, F; Johnson, T; Fasanmade, O; Furbert-Harris, P; Kittles, R; Vekich, M; Adegoke, O; Bonney, G; Collins, F
      In search of susceptibility genes for type 2 diabetes in West Africa: The design and results of the first phase of the AADM study

      ANNALS OF EPIDEMIOLOGY
    73. Kirpichnikov, D; Sowers, JR
      Diabetes mellitus and diabetes-associated vascular disease

      TRENDS IN ENDOCRINOLOGY AND METABOLISM
    74. Gartaganis, SP; Psyrojannis, AJ; Koliopoulos, JX; Mela, EK
      Contrast sensitivity function in patients with impaired oral glucose tolerance

      OPTOMETRY AND VISION SCIENCE
    75. Wahlqvist, ML
      Nutrition and diabetes in the Asia-Pacific region with reference to cardiovascular disease

      ASIA PACIFIC JOURNAL OF CLINICAL NUTRITION
    76. Kondo, K; Lukito, W; Savige, GS
      Lifecycle nutrition and cardiovascular health: the aged

      ASIA PACIFIC JOURNAL OF CLINICAL NUTRITION
    77. Dixon, JB; Dixon, ME; O'Brien, PE
      Pre-operative predictors of weight loss at 1-year after Lap-Band (R) surgery

      OBESITY SURGERY
    78. Khaw, KT; Wareham, N; Luben, R; Bingham, S; Oakes, S; Welch, A; Day, N
      Glycated haemoglobin, diabetes, and mortality in men in Norfolk cohort of European Prospective Investigation of Cancer and Nutrition (EPIC-Norfolk)

      BRITISH MEDICAL JOURNAL
    79. Despres, JP; Lemieux, I; Prud'homme, D
      Treatment of obesity: need to focus on high risk abdominally obese patients

      BRITISH MEDICAL JOURNAL
    80. Yngen, M; Ostenson, CG; Li, N; Hjemdahl, P; Wallen, NH
      Acute hyperglycemia increases soluble P-selectin in male patients with mild diabetes mellitus

      BLOOD COAGULATION & FIBRINOLYSIS
    81. Sougleri, M; Labropoulou-Karatza, C; Paraskevopoulou, P; Fragopanagou, H; Alexandrides, T
      Chronic hepatitis C virus infection without cirrhosis induces insulin resistance in patients with beta-thalassaemia major

      EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
    82. Berne, C
      Diabetes mellitus - a more solid ground for treatment

      JOURNAL OF INTERNAL MEDICINE
    83. Rolandsson, O; Hagg, E; Nilsson, M; Hallmans, G; Mincheva-Nilsson, L; Lernmark, A
      Prediction of diabetes with body mass index, oral glucose tolerance test and islet cell autoantibodies in a regional population

      JOURNAL OF INTERNAL MEDICINE
    84. Zimmet, P
      Globalization, coca-colonization and the chronic disease epidemic: can theDoomsday scenario be averted? (Reprinted from Journal of Internal Medicine, vol 247, pg 301-310, 2000)

      JOURNAL OF INTERNAL MEDICINE
    85. Gulliford, MC; Ukoumunne, OC
      Determinants of glycated haemoglobin in the general population: associations with diet, alcohol and cigarette smoking

      EUROPEAN JOURNAL OF CLINICAL NUTRITION
    86. Malalavidhane, S; Wickramasinghe, SMDN; Jansz, ER
      An aqueous extract of the green leafy vegetable Ipomoea aquatica is as effective as the oral hypoglycaemic drug tolbutamide in reducing the blood sugar levels of Wistar rats

      PHYTOTHERAPY RESEARCH
    87. Pietrobelli, DJ; Akopian, M; Olivieri, AO; Renauld, A; Garrido, D; Artese, R; Feldstein, CA
      Altered circadian blood pressure profile in patients with active acromegaly. Relationship with left ventricular mass and hormonal values

      JOURNAL OF HUMAN HYPERTENSION
    88. Lebovitz, HE
      Insulin resistance: definition and consequences

      EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
    89. Dostou, J; Gerich, J
      Pathogenesis of type 2 diabetes mellitus

      EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
    90. Pfohl, M; Schatz, H
      Strategies for the prevention of type 2 diabetes

      EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
    91. Creutzfeldt, W
      The entero-insular axis in type 2 diabetes - incretins as therapeutic agents

      EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
    92. Tamas, G; Kerenyi, Z
      Gestational diabetes: current aspects on pathogenesis and treatment

      EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
    93. Klevay, LM
      Iron overload can induce mild copper deficiency

      JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
    94. Ling, Z; Wu, D; Zambre, Y; Flamez, D; Drucker, DJ; Pipeleers, DG; Schuit, FC
      Glucagon-like peptide 1 receptor signaling influences topography of islet cells in mice

      VIRCHOWS ARCHIV-AN INTERNATIONAL JOURNAL OF PATHOLOGY
    95. Ponte, E; Tabaj, D; Maglione, M; Melato, M
      Diabetes mellitus and oral disease

      ACTA DIABETOLOGICA
    96. Busetto, L
      Visceral obesity and the metabolic syndrome: Effects of weight loss

      NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
    97. Fajas, L; Debril, MB; Auwerx, J
      PPAR gamma: An essential role in metabolic control

      NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
    98. Konrad, T; Markus, B; Allers, C; Vicini, P; Toffolo, G; Lakos, C; Viehmann, K; Hanisch, E; Encke, A; Cobelli, C; Usadel, KH
      Impact of cyclosporine and low-dose steroid therapy on insulin sensitivityand beta-cell function in patients with longterm liver grafts

      TRANSPLANT INTERNATIONAL
    99. Hjelmesaeth, J; Hartmann, A; Midtvedt, K; Aakhus, S; Stenstrom, J; Morkrid, L; Egeland, T; Tordarson, H; Fauchald, P
      Metabolic cardiovascular syndrome after renal transplantation

      NEPHROLOGY DIALYSIS TRANSPLANTATION
    100. Liebzeit, KA; Markowitz, JS; Caley, CF
      New onset diabetes and atypical antipsychotics

      EUROPEAN NEUROPSYCHOPHARMACOLOGY


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Documento generato il 07/06/20 alle ore 05:45:14