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A cascade of complex subtelomeric duplications during the evolution of thehominoid and old world monkey genomes
AMERICAN JOURNAL OF HUMAN GENETICS
Gene therapy of a mouse model of protoporphyria with a self-inactivating erythroid-specific lentiviral vector without preselection
MOLECULAR THERAPY
Adeno-associated virus 2-mediated transduction and erythroid lineage-restricted long-term expression of the human beta-globin gene in hematopoietic cells from homozygous beta-thalassemic mice
MOLECULAR THERAPY
Pharmacologic induction of fetal hemoglobin synthesis: Cellular and molecular mechanisms
PEDIATRIC PATHOLOGY & MOLECULAR MEDICINE
DNA replication origins: from sequence specificity to epigenetics
NATURE REVIEWS GENETICS
Phenotype-genotype relationships in monogenic disease: Lessons from the thalassaemias
NATURE REVIEWS GENETICS
Gene-trap mutagenesis: Past, present and beyond
NATURE REVIEWS GENETICS
The Hemoglobin O mutation in Indonesia: distribution and phenotypic expression
JOURNAL OF HUMAN GENETICS
A globin-coupled oxygen sensor from the facultatively alkaliphilic Bacillus halodurans C-125
EXTREMOPHILES
Enrichment of regulatory signals in conserved non-coding genomic sequence
BIOINFORMATICS
Beyond the locus control region: new light on beta-globin locus regulation
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
Interaction of fission yeast ORC with essential adenine/thymine stretches in replication origins
GENES TO CELLS
Poly(rC) binding proteins mediate poliovirus mRNA stability
RNA-A PUBLICATION OF THE RNA SOCIETY
The requirement for eukaryotic initiation factor 4A (eIF4A) in translationis in direct proportion to the degree of mRNA 5 ' secondary structure
RNA-A PUBLICATION OF THE RNA SOCIETY
Advances in experimental treatment of beta-thalassaemia
EXPERT OPINION ON INVESTIGATIONAL DRUGS
Mouse erythroblast formation is inhibited by anemia-inducing substance from the plasma of a patient with a malignant neoplasm
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
Clinical phenotype of triplicated alpha-globin genes and heterozygosity for beta(0)-thalassemia in Chinese subjects
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
Distinct mechanisms control RNA polymerase II recruitment to a tissue-specific locus control region and a downstream promoter
MOLECULAR CELL
Molecular cloning and sequence analysis of alpha- and beta-globin cDNAs from yellowtail, Seriola quinqueradiata
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
Rapid identification of hemoglobin variants by electrospray ionization mass spectrometry
BLOOD CELLS MOLECULES AND DISEASES
Targeted correction of the point mutations of beta-thalassemia and targeted mutagenesis of the nucleotide associated with HPFH by RNA/DNA oligonucleotides: Potential for beta-thalassemia gene therapy
BLOOD CELLS MOLECULES AND DISEASES
Polymorphisms in the transferrin 5 ' flanking region associated with differences in total iron binding capacity: Possible implications in iron homeostasis
BLOOD CELLS MOLECULES AND DISEASES
Cloning and characterization of a potential transcriptional activator of human gamma-globin genes
BLOOD CELLS MOLECULES AND DISEASES
Gene expression profiling during erythroid differentiation of K562 cells
BLOOD CELLS MOLECULES AND DISEASES
Generating mice with targeted mutations
NATURE MEDICINE
Growth hormone and insulin-like growth factor I axis and growth of children with different sickle cell anemia haplotypes
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
Localization of the 3 ' IgH locus elements that effect long-distance regulation of class switch recombination
IMMUNITY
Growth inhibition and differentiation induction in murine erythroleukemia cells by 4-hydroxynonenal
FREE RADICAL RESEARCH
Molecular and transcriptional regulation of megakaryocyte differentiation
STEM CELLS
Gene transfer into nonhuman primate hematopoietic stem cells: Implicationsfor gene therapy
STEM CELLS
Correction of genetic blood defects by gene transfer
CURRENT OPINION IN HEMATOLOGY
Pharmacologic induction of fetal hemoglobin: raising the therapeutic bar in sickle cell disease
CURRENT OPINION IN HEMATOLOGY
Phylogeny of the genus Chironomus (diptera) inferred from DNA sequences ofmitochondrial cytochrome b and cytochrome oxidase I
MOLECULAR PHYLOGENETICS AND EVOLUTION
Catarrhine phylogeny: Noncoding DNA evidence for a diphyletic origin of the mangabeys and for a human-chimpanzee clade
MOLECULAR PHYLOGENETICS AND EVOLUTION
Comparison of the DNA extraction methods for polymerase chain reaction amplification from formalin-fixed and paraffin-embedded tissues
DIAGNOSTIC MOLECULAR PATHOLOGY
Silencing of gene expression: implications for design of retrovirus vectors
REVIEWS IN MEDICAL VIROLOGY
A promising genetic approach to the treatment of beta-thalassemia
TRENDS IN CARDIOVASCULAR MEDICINE
Searching for the magic bullet against cancer: The butyrate saga
LEUKEMIA & LYMPHOMA
Sickle cell disease: no longer a single gene disorder
CURRENT OPINION IN PEDIATRICS
Usefulness of double gene construct for rapid identification of transgenicmice exhibiting tissue-specific gene expression
MOLECULAR REPRODUCTION AND DEVELOPMENT
Production of germ-line chimeras in rainbow trout by blastomere transplantation
MOLECULAR REPRODUCTION AND DEVELOPMENT
Monosomy for the most telomeric, gene-rich region of the short arm of human chromosome 16 causes minimal phenotypic effects
EUROPEAN JOURNAL OF HUMAN GENETICS
The endothelin receptor B (EDNRB) promoter displays heterogeneous, site specific methylation patterns in normal and tumor cells
HUMAN MOLECULAR GENETICS
Comparative genome analysis delimits a chromosomal domain and identifies key regulatory elements in the alpha globin cluster
HUMAN MOLECULAR GENETICS
Size matters: Use of YACs, BACs and PACs in transgenic animals
TRANSGENIC RESEARCH
Critical role of biklf in erythroid cell differentiation in zebrafish
CURRENT BIOLOGY
Chromatin remodeling in development and differentiation
CURRENT OPINION IN GENETICS & DEVELOPMENT
Gene therapy for genetic haematological disorders and immunodeficiencies
JOURNAL OF INTERNAL MEDICINE
The v-ErbA oncoprotein quenches the activity of an erythroid-specific enhancer
ONCOGENE
Mcl-1, an early-induction molecule, modulates activin A-induced apoptosis and differentiation of CML cells
ONCOGENE
Chromatin alteration, transcription and replication: What's the opening line to the story?
ONCOGENE
Emerging strategies in microbial haem capture
MOLECULAR MICROBIOLOGY
Genomic context modulates insulator activity through promoter competition
DEVELOPMENT
Characterisation of Wnt gene expression during the differentiation of murine embryonic stem cells in vitro: role of Wnt3 in enhancing haematopoietic differentiation
MECHANISMS OF DEVELOPMENT
Spontaneous germline amplification and translocation of a transgene array
MUTATION RESEARCH-DNA REPAIR
Crystallization and preliminary X-ray analysis of neural haemoglobin from the nemertean worm Cerebratulus lacteus
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
Clinical and hematological features of beta(+)-thalassemia (IVS-1 nt 5, G-C mutation) in Thai patients
EUROPEAN JOURNAL OF HAEMATOLOGY
Loss of critical palindromic transgene promoter sequence in chemically induced Tg.AC mouse skin papillomas expressing transgene-derived mRNA
MOLECULAR CARCINOGENESIS
Loss of palindromic symmetry Tg.AC mice with a nonresponder phenotype
MOLECULAR CARCINOGENESIS
A view through the clouds of imprinting
FASEB JOURNAL
Functionally distinct, sequence-specific replicator and origin elements are required for Drosophila chorion gene amplification
GENES & DEVELOPMENT
Expression and replication timing patterns of wildtype and translocated BCL2 genes
GENOMICS
In vivo DNA-protein interactions at hypersensitive site 3.5 of the human beta-globin locus control region
BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE
Higher-order folding of heterochromatin: Protein bridges span the nucleosome arrays
BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE
Subtelomeric sequence from the right arm of Schizosaccharomyces pombe chromosome I contains seven permease genes
YEAST
Post-transcriptional effects of interleukin-3, interferon-gamma, erythropoietin and butyrate on in vitro hemoglobin chain synthesis in congenital hemolytic anemia
HAEMATOLOGICA
Molecular characterization of thalassemia intermedia with homozygous Hb Malay and Hb Malay/HbE in Thai patients
HAEMATOLOGICA
Diagnosis of concurrent hemoglobin H disease and heterozygous beta-thalassemia
HAEMATOLOGICA
Thalassemia screening based on red cell indices in the Chinese
HAEMATOLOGICA
Origin and spread of HbG-San Jose in Southern Italy
HAEMATOLOGICA
Different geographic origins of Hb constant spring [alpha(2) codon 142 TAA-> CAA]
HAEMATOLOGICA
Two-domain hemoglobin gene of the water flea Moina macrocopa: duplication in the ancestral Cladocera, diversification, and loss of a bridge intron
GENE
Role of the multifunctional CDP/Cut/Cux homeodomain transcription factor in regulating differentiation, cell growth and development
GENE
Leukocyte-specific expression of the pp52 (LSP1) promoter is controlled bythe cis-acting pp52 silencer and anti-silencer elements
GENE
Erythroid carbonic anhydrase and hsp70 expression in chick embryonic development: role of cAMP and hypoxia
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
Could capillary zone electrophoresis of tryptic peptides be used for the characterization of hemoglobin variants?
HEMOGLOBIN
The thalassemia syndromes: Molecular characterization in the spanish population
HEMOGLOBIN
A novel splice acceptor site mutation of the alpha 2-globin gene causing alpha-thalassemia
HEMOGLOBIN
Forty-four years (1955-1999) devoted to hemoglobin research: Titus H. J. Huisman (1923-1999) - In memoriam
HEMOGLOBIN
Abnormal hemoglobins: Laboratory methods
HEMOGLOBIN
Modulation of fetal hemoglobin in sickle cell anemia
HEMOGLOBIN
beta-Thalassemia in Turkey: A review of the clinical, epidemiological, molecular, and evolutionary aspects
HEMOGLOBIN
Molecular spectrum of beta-thalassemia in the Iranian province of hormozgan
HEMOGLOBIN
A Korean family with a dominantly inherited beta-thalassemia due to Hb Durham-NC/Brescia [beta 114(G16)Leu -> Pro]
HEMOGLOBIN
Molecular pathogenesis and clinical variability of beta-thalassemia syndromes among Indians
AMERICAN JOURNAL OF HEMATOLOGY
Hemoglobin H (Hb H) disease in Canada: Molecular diagnosis and review of 116 cases
AMERICAN JOURNAL OF HEMATOLOGY
Spectrum of beta-thalassemia in Jordan: Identification of two novel mutations
AMERICAN JOURNAL OF HEMATOLOGY
Non-anemic homozygous beta degrees thalassemia in an african-american family: Association of high fetal hemoglobin levels with beta thalassemia alleles
AMERICAN JOURNAL OF HEMATOLOGY
Molecular characteristics of pediatric patients with sickle cell anemia and stroke
AMERICAN JOURNAL OF HEMATOLOGY
Molecular characterization of hemoglobin C in Thailand
AMERICAN JOURNAL OF HEMATOLOGY
Frequency of the 677 C -> T mutation of the methylenetetrahydrofolate reductase gene among Kuwaiti sickle cell disease patients
AMERICAN JOURNAL OF HEMATOLOGY
A gamma-haplotypes: A new group of genetic markers for thalassemic mutations inside the 5 ' regulatory region of the human A gamma-globin gene
AMERICAN JOURNAL OF HEMATOLOGY
Insulator: from chromatin domain boundary to gene regulation
HUMAN GENETICS
SMN gene duplication and the emergence of the SMN2 gene occurred in distinct hominids: SMN2 is unique to Homo sapiens
HUMAN GENETICS
Identification of factors mediating the developmental regulation of the early acting-3.9 kb chicken lysozyme enhancer element
NUCLEIC ACIDS RESEARCH
The human growth hormone locus control region mediates long-distance transcriptional activation independent of nuclear matrix attachment regions
NUCLEIC ACIDS RESEARCH
Enhancer activity of HS2 of the human P-LCR is modulated by distance from the key nucleosome
NUCLEIC ACIDS RESEARCH
Induction of embryonic hematopoietic and endothelial stem/progenitor cellsby hedgehog-mediated signals
DIFFERENTIATION
Primary structure of alpha-globin chains from river buffalo (Bubalus bubalis L.) hemoglobins
JOURNAL OF PROTEIN CHEMISTRY
Unanticipated repression function linked to erythroid Kruppel-like factor
MOLECULAR AND CELLULAR BIOLOGY