Catalogo Articoli (Spogli Riviste)

HELP
ATTENZIONE: attualmente gli articoli Current Contents (fonte ISI) a partire dall'anno 2002 sono consultabili sulla Risorsa On-Line

Le informazioni sugli articoli di fonte ISI sono coperte da copyright

La ricerca find articoli where soggetti phrase all words 'GAMMA-SECRETASE' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 108 riferimenti
Si mostrano 100 riferimenti a partire da 1
Selezionare un intervallo

Per ulteriori informazioni selezionare i riferimenti di interesse.

    1. Golde, TE; Younkin, SG
      Presenilins as therapeutic targets for the treatment of Alzheimer's disease

      TRENDS IN MOLECULAR MEDICINE
    2. Chen, FS; Yu, G; Arawaka, S; Nishimura, M; Kawarai, T; Yu, H; Tandon, A; Supala, A; Song, YQ; Rogaeva, E; Milman, P; Sato, C; Yu, C; Janus, C; Lee, J; Song, LX; Zhang, LL; Fraser, PE; St George-Hyslop, PH
      Nicastrin binds to membrane tethered Notch

      NATURE CELL BIOLOGY
    3. Armogida, M; Petit, A; Vincent, B; Scarzello, S; da Costa, CA; Checler, F
      Endogenous beta-amyloid production in presenilin-deficient embryonic mousefibroblasts

      NATURE CELL BIOLOGY
    4. De Strooper, B; Annaert, W
      Presenilins and the intramembrane proteolysis of proteins: facts and fiction

      NATURE CELL BIOLOGY
    5. Shastry, BS
      Molecular and cell biological aspects of Alzheimer disease

      JOURNAL OF HUMAN GENETICS
    6. Moss, ML; White, JM; Lambert, MH; Andrews, RC
      TACE and other ADAM proteases as targets for drug discovery

      DRUG DISCOVERY TODAY
    7. Jhee, S; Shiovitz, T; Crawford, AW; Cutler, NR
      beta-amyloid therapies in Alzheimer's disease

      EXPERT OPINION ON INVESTIGATIONAL DRUGS

    8. Statine-derived tetrapeptide inhibitors of beta-secretase - Elan Pharm., Inc.: WO0077030

      EXPERT OPINION ON THERAPEUTIC PATENTS
    9. Dominguez, DI; De Strooper, B; Annaert, W
      Secretases as therapeutic targets for the treatment of Alzheimer's disease

      AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS
    10. Clippingdale, AB; Wade, JD; Barrow, CJ
      The amyloid-beta peptide and its role in Alzheimer's disease

      JOURNAL OF PEPTIDE SCIENCE
    11. Hitchcock, AL; Krebber, H; Frietze, S; Lin, A; Latterich, M; Silver, PA
      The conserved Np14 protein complex mediates proteasome-dependent membrane-bound transcription factor activation

      MOLECULAR BIOLOGY OF THE CELL
    12. Bayer, TA; Wirths, O; Majtenyi, K; Hartmann, T; Multhaup, G; Beyreuther, K; Czech, C
      Key factors in Alzheimer's disease: beta-amyloid precursor protein processing, metabolism and intraneuronal transport

      BRAIN PATHOLOGY
    13. Steiner, H; Winkler, E; Shearman, MS; Prywes, R; Haass, C
      Endoproteolysis of the ER stress transducer ATF6 in the presence of functionally inactive presenilins

      NEUROBIOLOGY OF DISEASE
    14. Fortini, ME
      Notch and Presenilin: a proteolytic mechanism emerges

      CURRENT OPINION IN CELL BIOLOGY
    15. Paganelli, AR; Ocana, OH; Prat, MI; Franco, PG; Lopez, SL; Morelli, L; Adamo, AM; Riccomagno, MM; Matsubara, E; Shoji, M; Affranchino, JL; Castano, EM; Carrasco, AE
      The Alzheimer-related gene presenilin-1 facilitates sonic hedgehog expression in Xenopus primary neurogenesis

      MECHANISMS OF DEVELOPMENT
    16. Lewis, PA; Piper, S; Baker, M; Onstead, L; Murphy, MP; Hardy, J; Wang, R; McGowan, E; Golde, TE
      Expression of BRI-amyloid beta peptide fusion proteins: a novel method forspecific high-level expression of amyloid beta peptides

      BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
    17. Annaert, WG; Esselens, C; Baert, V; Boeve, C; Snellings, G; Cupers, P; Craessaerts, K; De Strooper, B
      Interaction with telencephalin and the amyloid precursor protein predicts a ring structure for presenilins

      NEURON
    18. Yu, HK; Saura, CA; Choi, SY; Sun, LD; Yang, XD; Handler, M; Kawarabayashi, T; Younkin, L; Fedeles, B; Wilson, MA; Younkin, S; Kandel, ER; Kirkwood, A; Shen, J
      APP processing and synaptic plasticity in presenilin-1 conditional knockout mice

      NEURON
    19. Hartmann, D; Tournoy, J; Saftig, P; Annaert, W; De Strooper, B
      Implication of APP secretases in notch signaling

      JOURNAL OF MOLECULAR NEUROSCIENCE
    20. Thinakaran, G
      Metabolism of presenilins

      JOURNAL OF MOLECULAR NEUROSCIENCE
    21. Steiner, H; Haass, C
      Nuclear signaling - A common function of presenilin substrates?

      JOURNAL OF MOLECULAR NEUROSCIENCE
    22. Schenk, D; Games, D; Seubert, P
      Potential treatment opportunities for Alzheimer's disease through inhibition of secretases and A beta immunization

      JOURNAL OF MOLECULAR NEUROSCIENCE
    23. Pinnix, I; Council, JE; Roseberry, B; Onstead, L; Mallender, W; Sucic, J; Sambamurti, K
      Convertases other than furin cleave beta-secretase to its mature form

      FASEB JOURNAL
    24. Russo, E
      Hot papers - Interpreting the signaling of notch - Comment

      SCIENTIST
    25. Popescu, BO; Cedazo-Minguez, A; Popescu, LM; Winblad, B; Cowburn, RF; Ankarcrona, M
      Caspase cleavage of exon 9 deleted presenilin-1 is an early event in apoptosis induced by calcium ionophore A 23187 in SH-SY5Y neuroblastoma cells

      JOURNAL OF NEUROSCIENCE RESEARCH
    26. Mann, DMA; Takeuchi, A; Sato, S; Cairns, NJ; Lantos, PL; Rossor, MN; Haltia, M; Kalimo, H; Iwatsubo, T
      Cases of Alzheimer's disease due to deletion of exon 9 of the presenilin-1gene show an unusual but characteristic beta-amyloid pathology known as 'cotton wool' plaques

      NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
    27. Yamamoto, A; Behl, C
      Human Nck-associated protein1 and its binding protein affect the metabolism of beta-amyloid precursor protein with Swedish mutation

      NEUROSCIENCE LETTERS
    28. Vandermeeren, M; Geraerts, M; Pype, S; Dillen, L; Van Hove, C; Mercken, M
      The functional gamma-secretase inhibitor prevents production of amyloid beta 1-34 in human and murine cell lines

      NEUROSCIENCE LETTERS
    29. Frisen, J; Lendahl, U
      Oh no, Notch again!

      BIOESSAYS
    30. Jack, C; Berezovska, O; Wolfe, MS; Hyman, BT
      Effect of PS1 deficiency and an APP gamma-secretase inhibitor on Notch1 signaling in primary mammalian neurons

      MOLECULAR BRAIN RESEARCH
    31. Nadin, A; Lopez, JMS; Neduvelil, JG; Thomas, SR
      A stereocontrolled synthesis of 2R-benzyl-5S-tert-butoxycarbonylamino-4R-(tert-butyldimethylsilanyloxy)-6-phenyl-hexanoic acid (Phe-Phe hydroxyethylene dipeptide isostere)

      TETRAHEDRON
    32. Esler, WP; Wolfe, MS
      Biomedicine - A portrait of Alzheimer secretases - New features and familiar faces

      SCIENCE
    33. Selkoe, DJ
      Alzheimer's disease: Genes, proteins, and therapy

      PHYSIOLOGICAL REVIEWS
    34. Kamal, A; Almenar-Queralt, A; LeBlanc, JF; Roberts, EA; Goldstein, LSB
      Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP

      NATURE
    35. Levitan, D; Lee, J; Song, LX; Manning, R; Wong, G; Parker, E; Zhang, LL
      PS1N-and C-terminal fragments form a complex that functions in APP processing and Notch signaling

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    36. Selkoe, DJ
      Presenilin, Notch, and the genesis and treatment of Alzheimer's disease

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    37. Fassbender, K; Simons, M; Bergmann, C; Stroick, M; Lutjohann, D; Keller, P; Runz, H; Kuhl, S; Bertsch, T; von Bergmannn, K; Hennerici, M; Beyreuther, K; Hartmann, T
      Simvastatin strongly reduces levels of Alzheimer's disease beta-amyloid peptides A beta 42 and A beta 40 in vitro and in vivo

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    38. Struhl, G; Greenwald, I
      Presenilin-mediated transmembrane cleavage is required for Notch signal transduction in Drosophila

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    39. Kametani, F; Tanaka, K; Usami, M; Maruyama, K; Mori, H
      Human wild presenilin-1 mimics the effect of the mutant presenilin-1 on the processing of Alzheimer's amyloid precursor protein in PC12D cells

      JOURNAL OF THE NEUROLOGICAL SCIENCES
    40. Cupers, P; Orlans, I; Craessaerts, K; Annaert, W; De Strooper, B
      The amyloid precursor protein (APP)-cytoplasmic fragment generated by gamma-secretase is rapidly degraded but distributes partially in a nuclear fraction of neurones in culture

      JOURNAL OF NEUROCHEMISTRY
    41. Checler, F
      The multiple paradoxes of presenilins

      JOURNAL OF NEUROCHEMISTRY
    42. Dovey, HF; John, V; Anderson, JP; Chen, LZ; Andrieu, PD; Fang, LY; Freedman, SB; Folmer, B; Goldbach, E; Holsztynska, EJ; Hu, KL; Johnson-Wood, KL; Kennedy, SL; Kholedenko, D; Knops, JE; Latimer, LH; Lee, M; Liao, Z; Lieberburg, IM; Motter, RN; Mutter, LC; Nietz, J; Quinn, KP; Sacchi, KL; Seubert, PA; Shopp, GM; Thorsett, ED; Tung, JS; Wu, J; Yang, S; Yin, CT; Schenk, DB; May, PC; Altstiel, LD; Bender, MH; Boggs, LN; Britton, TC; Clemens, JC; Czilli, DL; Dieckman-McGinty, DK; Droste, JJ; Fuson, KS; Gitter, BD; Hyslop, PA; Johnstone, EM; Li, WY; Little, SP; Mabry, TE; Miller, FD; Ni, B; Nissen, JS; Porter, WJ; Potts, BD; Reel, JK; Stephenson, D; Su, Y; Shipley, LA; Whitesitt, CA; Yin, T; Audia, JE
      Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain

      JOURNAL OF NEUROCHEMISTRY
    43. Lee, CW; Zhuang, ZP; Kung, MP; Plossl, K; Skovronsky, D; Gur, T; Hou, C; Trojanowski, JQ; Lee, WMY; Kung, HF
      Isomerization of (Z,Z) to (E,E) 1-bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene in strong base: Probes for amyloid plaques in the brain

      JOURNAL OF MEDICINAL CHEMISTRY
    44. Wolfe, MS
      Secretase targets for Alzheimer's disease: Identification and therapeutic potential

      JOURNAL OF MEDICINAL CHEMISTRY
    45. Zhuang, ZP; Kung, MP; Hou, C; Skovronsky, DM; Gur, TL; Plossl, K; Trojanowski, JQ; Lee, VMY; Kung, HF
      Radioiodinated styrylbenzenes and thioflavins as probes for amyloid aggregates

      JOURNAL OF MEDICINAL CHEMISTRY
    46. Dingwall, C
      Spotlight on BACE: The secretases as targets for treatment in Alzheimer disease

      JOURNAL OF CLINICAL INVESTIGATION
    47. Cupers, P; Bentahir, M; Craessaerts, K; Orlans, I; Vanderstichele, H; Saftig, P; De Strooper, B; Annaert, W
      The discrepancy between presenilin subcellular localization and gamma-secretase processing of amyloid precursor protein

      JOURNAL OF CELL BIOLOGY
    48. Kim, JW; Chang, TS; Lee, JE; Huh, SH; Yeon, SW; Yang, WS; Joe, CO; Mook-Jung, I; Tanzi, RE; Kim, TW; Choi, EJ
      Negative regulation of the SAPK/JNK signaling pathway by presenilin 1

      JOURNAL OF CELL BIOLOGY
    49. Steinhilb, ML; Turner, RS; Gaut, JR
      The protease inhibitor, MG132, blocks maturation of the amyloid precursor protein Swedish mutant preventing cleavage by beta-secretase

      JOURNAL OF BIOLOGICAL CHEMISTRY
    50. Robert, SJ; Zugaza, JL; Fischmeister, R; Gardier, AM; Lezoualc'h, F
      The human serotonin 5-HT4 receptor regulates secretion of non-amyloidogenic precursor protein

      JOURNAL OF BIOLOGICAL CHEMISTRY
    51. Wiltfang, J; Esselmann, H; Cupers, P; Neumann, M; Kretzschmar, H; Beyermann, M; Schleuder, D; Jahn, H; Ruther, E; Kornhuber, J; Annaert, W; De Strooper, B; Saftig, P
      Elevation of beta-amyloid peptide 2-42 in sporadic and familial Alzheimer's disease and its generation in PS1 knockout cells

      JOURNAL OF BIOLOGICAL CHEMISTRY
    52. Kim, SH; Leem, JY; Lah, JJ; Slunt, HH; Levey, AI; Thinakaran, G; Sisodia, SS
      Multiple effects of aspartate mutant presenilin 1 on the processing and trafficking of amyloid precursor protein

      JOURNAL OF BIOLOGICAL CHEMISTRY
    53. Saxena, MT; Schroeter, EH; Mumm, JS; Kopan, R
      Murine Notch homologs (N1-4) undergo presenilin-dependent proteolysis

      JOURNAL OF BIOLOGICAL CHEMISTRY
    54. Kimberly, WT; Zheng, JB; Guenette, SY; Selkoe, DJ
      The intracellular domain of the beta-amyloid precursor protein is stabilized by Fe65 and translocates to the nucleus in a Notch-like manner

      JOURNAL OF BIOLOGICAL CHEMISTRY
    55. Iwata, H; Tomita, T; Maruyama, K; Iwatsubo, T
      Subcellular compartment and molecular subdomain of beta-amyloid precursor protein relevant to the A beta 42-promoting effects of Alzheimer mutant presenilin 2

      JOURNAL OF BIOLOGICAL CHEMISTRY
    56. Maltese, WA; Wilson, S; Tan, YZ; Suomensaari, S; Sinha, S; Barbour, R; McConlogue, L
      Retention of the Alzheimer's amyloid precursor fragment C99 in the endoplasmic reticulum prevents formation of amyloid beta-peptide

      JOURNAL OF BIOLOGICAL CHEMISTRY
    57. Steiner, H; Revesz, T; Neumann, M; Romig, H; Grim, MG; Pesold, B; Kretzschmar, HA; Hardy, J; Holton, JL; Baumeister, R; Houlden, H; Haass, C
      A pathogenic presenilin-1 deletion causes abberrant A beta 42 production in the absence of congophilic amyloid plaques

      JOURNAL OF BIOLOGICAL CHEMISTRY
    58. Cervantes, S; Gonzalez-Duarte, R; Marfany, G
      Homodimerization of presenilin N-terminal fragments is affected by mutations linked to Alzheimer's disease

      FEBS LETTERS
    59. Nunan, J; Shearman, MS; Checler, F; Cappai, R; Evin, G; Beyreuther, K; Masters, CL; Small, DH
      The C-terminal fragment of the Alzheimer's disease amyloid protein precursor is degraded by a proteasome-dependent mechanism distinct from gamma-secretase

      EUROPEAN JOURNAL OF BIOCHEMISTRY
    60. Xie, J; Chang, XW; Zhang, XJ; Guo, Q
      Aberrant induction of Par-4 is involved in apoptosis of hippocampal neurons in presenilin-1 M146V mutant knock-in mice

      BRAIN RESEARCH
    61. Heyn, SN; Vulliet, PR
      Presenilin 1 mutations increase amyloid precursor protein production and proteolysis in Xenopus laevis oocytes

      BRAIN RESEARCH
    62. Evin, G; Sharples, RA; Weidemann, A; Reinhard, FBM; Carbone, V; Culvenor, JG; Holsinger, RMD; Sernee, MF; Beyreuther, K; Masters, CL
      Aspartyl protease inhibitor pepstatin binds to the presenilins of Alzheimer's disease

      BIOCHEMISTRY
    63. Park, IH; Jung, MW; Mori, H; Mook-Jung, I
      Zinc enhances synthesis of presenilin 1 in mouse primary cortical culture

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    64. Selkoe, DJ; Xia, W; Kimberly, WT; Vekrellis, K; Walsh, D; Esler, WP; Wolfe, MS
      Mechanisms of A beta production and A beta degradation: Routes to the treatment of Alzheimer's disease

      ALZHEIMER'S DISEASE
    65. Grimm, HS; Lichtenthaler, SF; Beyreuther, K; Hartmann, T
      Intracellular and secreted A beta(42/40) ratios are differently influencedby APP mutations

      ALZHEIMER'S DISEASE
    66. Song, WH; Yankner, BA
      Presenilins and notch signaling pathway

      ALZHEIMER'S DISEASE
    67. Steiner, H; Haass, C
      A novel protease active site motif conserved in presenilins and polytopic bacterial aspartyl proteases?

      ALZHEIMER'S DISEASE
    68. Steiner, H; Haass, C
      Intramembrane proteolysis by presenilins

      NATURE REVIEWS MOLECULAR CELL BIOLOGY
    69. Thorsett, ED; Latimer, LH
      Therapeutic approaches to Alzheimer's disease

      CURRENT OPINION IN CHEMICAL BIOLOGY
    70. Struhl, G; Adachi, A
      Requirements for presenilin-dependent cleavage of notch and other transmembrane proteins

      MOLECULAR CELL
    71. Zhang, DM; Levitan, D; Yu, G; Nishimura, M; Chen, FS; Tandon, A; Kawarai, T; Arawaka, S; Supala, A; Song, YQ; Rogaeva, E; Liang, Y; Holmes, E; Milman, P; Sato, C; Zhang, LL; St George-Hyslop, P
      Mutation of the conserved N-terminal cysteine (Cys92) of human presenilin 1 causes increased A beta(42) secretion in mammalian cells but impaired Notch/lin-12 signalling in C. elegans

      NEUROREPORT
    72. Weinmaster, G
      Notch signal transduction: a real Rip and more

      CURRENT OPINION IN GENETICS & DEVELOPMENT
    73. Annaert, W; De Strooper, B
      Neuronal models to study amyloid precursor protein expression and processing in vitro

      BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
    74. Kopan, R; Goate, A
      A common enzyme connects Notch signaling and Alzheimer's disease

      GENES & DEVELOPMENT
    75. Selkoe, DJ
      The genetics and molecular pathology of Alzheimer's disease - Roles of amyloid and the presenilins

      NEUROLOGIC CLINICS
    76. Siman, R; Reaume, AG; Savage, MJ; Trusko, S; Lin, YG; Scott, RW; Flood, DG
      Presenilin-1 P264L knock-in mutation: Differential effects on A beta production, amyloid deposition, and neuronal vulnerability

      JOURNAL OF NEUROSCIENCE
    77. Morihara, T; Katayama, T; Sato, N; Yoneda, T; Manabe, T; Hitomi, J; Abe, H; Imaizumi, K; Tohyama, M
      Absence of endoproteolysis but no effects on amyloid beta production by alternative splicing forms of presenilin-1, which lack exon 8 and replace D257A

      MOLECULAR BRAIN RESEARCH
    78. Yu, CY; Yang, ZY; Blanchong, CA; Miller, W
      The human and mouse MHC class III region: a parade of 21 genes at the centromeric segment

      IMMUNOLOGY TODAY
    79. Olson, RE; Thompson, LA
      Secretase inhibitors as therapeutics for Alzheimer's disease

      ANNUAL REPORTS IN MEDICINAL CHEMISTRY, VOL 35
    80. Yu, G; Nishimura, M; Arawaka, S; Levitan, D; Zhang, LL; Tandon, A; Song, YQ; Rogaeva, E; Chen, FS; Kawaral, T; Supala, A; Levesque, L; Yu, H; Yang, DS; Holmes, E; Millman, P; Liang, Y; Zhang, DM; Xu, DH; Sato, C; Rogaev, E; Smith, M; Janus, C; Zhang, YN; Aebersold, R; Farrer, L; Sorbi, S; Bruni, A; Fraser, P; St George-Hyslop, P
      Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and beta APP processing

      NATURE
    81. Xia, WM; Ray, WJ; Ostaszewski, BL; Rahmati, T; Kimberly, WT; Wolfe, MS; Zhang, JM; Goate, AM; Selkoe, DJ
      Presenilin complexes with the C-terminal fragments of amyloid precursor protein at the sites of amyloid beta-protein generation

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    82. Kulic, L; Walter, J; Multhaup, G; Teplow, DB; Baumeister, R; Romig, H; Capell, A; Steiner, H; Haass, C
      Separation of presenilin function in amyloid beta-peptide generation and endoproteolysis of Notch

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    83. Pastorcic, M; Das, HK
      Regulation of transcription of the human presenilin-1 gene by Ets transcription factors and the p53 protooncogene

      JOURNAL OF BIOLOGICAL CHEMISTRY
    84. Capell, A; Steiner, H; Willem, M; Kaiser, H; Meyer, C; Walter, J; Lammich, S; Multhaup, G; Haass, C
      Maturation and pro-peptide cleavage of beta-secretase

      JOURNAL OF BIOLOGICAL CHEMISTRY
    85. Verdile, G; Martins, RN; Duthie, M; Holmes, E; St George-Hyslop, PH; Fraser, PE
      Inhibiting amyloid precursor protein C-terminal cleavage promotes an interaction with presenilin 1

      JOURNAL OF BIOLOGICAL CHEMISTRY
    86. Sudoh, S; Hua, G; Kawamura, Y; Maruyama, K; Komano, H; Yanagisawa, K
      Intracellular site of gamma-secretase cleavage for A beta 42 generation inNeuro 2a cells harbouring a presenilin 1 mutation

      EUROPEAN JOURNAL OF BIOCHEMISTRY
    87. Mumm, JS; Kopan, R
      Notch signaling: From the outside in

      DEVELOPMENTAL BIOLOGY
    88. Lewis, PA; Perez-Tur, J; Golde, TE; Hardy, J
      The presenilin 1 C92S mutation increases A beta 42 production

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    89. Yu, G; Chen, F; Nishimura, M; Steiner, H; Tandon, A; Kawarai, T; Arawaka, S; Supar, A; Song, YQ; Rogaeva, E; Holmes, E; Zhang, M; Milman, P; Fraser, P; Haass, C; St George-Hyslop, P
      Mutation of conserved aspartates affect maturation of presenilin 1 and presenilin 2 complexes

      ACTA NEUROLOGICA SCANDINAVICA
    90. Harman, D
      Alzheimer's disease: A hypothesis on pathogenesis

      JOURNAL OF THE AMERICAN AGING ASSOCIATION
    91. Scheper, W; Annaert, W; Cupers, P; Saftig, P; De Strooper, B
      Function and dysfunction of the presenilins

      ALZHEIMERS REPORTS
    92. Steiner, H; Capell, A; Leimer, U; Haass, C
      Genes and mechanisms involved in beta-amyloid generation and Alzheimer's disease

      EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
    93. Saftig, P; Hartmann, D; De Strooper, P
      The function of presenilin-1 in amyloid beta-peptide generation and brain development

      EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
    94. Johnston, JA; Jensen, M; Lannfelt, L; Walker, B; Williams, CH
      Inhibition of prolylendopeptidase does not affect gamma-secretase processing of amyloid precursor protein in a human neuroblastoma cell line

      NEUROSCIENCE LETTERS
    95. Martoglio, B
      Transmembrane segment proteases

      PROTOPLASMA
    96. Petanceska, SS; Gandy, S
      The phosphatidylinositol 3-kinase inhibitor wortmannin alters the metabolism of the Alzheimer's amyloid precursor protein

      JOURNAL OF NEUROCHEMISTRY
    97. Christie, G; Markwell, RE; Gray, CW; Smith, L; Godfrey, F; Mansfield, F; Wadsworth, H; King, R; McLaughlin, M; Cooper, DG; Ward, RV; Howlett, DR; Hartmann, T; Lichtenthaler, SF; Beyreuther, K; Underwood, J; Gribble, SK; Cappai, R; Masters, CL; Tamaoka, A; Gardner, RL; Rivett, AJ; Karran, EH; Allsop, D
      Alzheimer's disease: Correlation of the suppression of beta-amyloid peptide secretion from cultured cells with inhibition of the chymotrypsin-like activity of the proteasome

      JOURNAL OF NEUROCHEMISTRY
    98. Figueiredo-Pereira, ME; Efthimiopoulos, S; Tezapsidis, N; Buku, A; Ghiso, J; Mehta, P; Robakis, NK
      Distinct secretases, a cysteine protease and a serine protease, generate the C termini of amyloid beta-proteins A beta(1-40) and A beta(1-42), respectively

      JOURNAL OF NEUROCHEMISTRY
    99. Annaert, WG; Levesque, L; Craessaerts, K; Dierinck, I; Snellings, G; Westaway, D; George-Hyslop, PS; Cordell, B; Fraser, P; De Strooper, B
      Presenilin 1 controls gamma-secretase processing of amyloid precursor protein in pre-Golgi compartments of hippocampal neurons

      JOURNAL OF CELL BIOLOGY
    100. Steiner, H; Pesold, B; Haass, C
      An in vivo assay for the identification of target proteases which cleave membrane-associated substrates

      FEBS LETTERS


ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/02/20 alle ore 19:25:26