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La ricerca find articoli where soggetti phrase all words 'FETAL FIBROBLASTS' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 106 riferimenti
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    1. McEvoy, TG; Robinson, JJ; Sinclair, KD
      Developmental consequences of embryo and cell manipulation in mice and farm animals

      REPRODUCTION
    2. Denning, C; Burl, S; Ainslie, A; Bracken, J; Dinnyes, A; Fletcher, J; King, T; Ritchie, M; Ritchie, WA; Rollo, M; de Sousa, P; Travers, A; Wilmut, I; Clark, AJ
      Deletion of the alpha(1,3)galactosyl transferase (GGTA1) gene and the prion protein (PrP) gene in sheep

      NATURE BIOTECHNOLOGY
    3. Kang, YK; Koo, DB; Park, JS; Choi, YH; Chung, AS; Lee, KK; Han, YM
      Aberrant methylation of donor genome in cloned bovine embryos

      NATURE GENETICS
    4. Bono, P; Rubin, K; Higgins, JMG; Hynes, RO
      Layilin, a novel integral membrane protein, is a hyaluronan receptor

      MOLECULAR BIOLOGY OF THE CELL
    5. Tian, XC; Kubota, C; Yang, X
      Cloning of aged animals: A medical model for tissue and organ regeneration

      TRENDS IN CARDIOVASCULAR MEDICINE
    6. Daniels, R; Hall, VJ; French, AJ; Korfiatis, NA; Trounson, AO
      Comparison of gene transcription in cloned bovine embryos produced by different nuclear transfer techniques

      MOLECULAR REPRODUCTION AND DEVELOPMENT
    7. Booth, PJ; Holm, P; Vajta, G; Greve, T; Callesen, H
      Effect of two activation treatments and age of blastomere karyoplasts on in vitro development of bovine nuclear transfer embryos

      MOLECULAR REPRODUCTION AND DEVELOPMENT
    8. Bondioli, K; Ramsoondar, J; Williams, B; Costa, C; Fodor, W
      Cloned pigs generated from cultured skin fibroblasts derived from a H-transferase transgenic boar

      MOLECULAR REPRODUCTION AND DEVELOPMENT
    9. Arat, S; Rzucidlo, SJ; Gibbons, J; Miyoshi, K; Stice, SL
      Production of transgenic bovine embryos by transfer of transfected granulosa cells into enucleated oocytes

      MOLECULAR REPRODUCTION AND DEVELOPMENT
    10. Alberio, R; Brero, A; Motlik, J; Cremer, T; Wolf, E; Zakhartchenko, V
      Remodeling of donor nuclei, DNA-synthesis, and ploidy of bovine cumulus cell nuclear transfer embryos: Effect of activation protocol

      MOLECULAR REPRODUCTION AND DEVELOPMENT
    11. An, XR; Gou, KM; Chen, YF
      Production of transgenic blastocyst of sheep by somatic cell cloning

      CHINESE SCIENCE BULLETIN
    12. Ikeda, K; Takahashi, Y
      Effects of maturational age of porcine oocytes on the induction of activation and development in vitro following somatic cell nuclear transfer

      JOURNAL OF VETERINARY MEDICAL SCIENCE
    13. Hill, JR; Winger, QA; Burghardt, RC; Westhusin, ME
      Bovine nuclear transfer embryo development using cells derived from a cloned fetus

      ANIMAL REPRODUCTION SCIENCE
    14. Kuhholzer, B; Prather, RS
      Synchronization of porcine fetal fibroblast cells with topoisomerase-inhibitor hoechst 33342

      ANIMAL REPRODUCTION SCIENCE
    15. Tyteca, D; Van Der Smissen, P; Van Bambeke, F; Leys, K; Tulkens, PM; Courtoy, PJ; Mingeot-Leclercq, MP
      Azithromycin, a lysosomotropic antibiotic, impairs fluid-phase pinocytosisin cultured fibroblasts

      EUROPEAN JOURNAL OF CELL BIOLOGY
    16. Niemann, H; Rath, D
      Progress in reproductive biotechnology in swine

      THERIOGENOLOGY
    17. Westhusin, ME; Long, CR; Shin, T; Hill, JR; Looney, CR; Pryor, JH; Piedrahita, JA
      Cloning to reproduce desired genotypes

      THERIOGENOLOGY
    18. Rideout, WM; Eggan, K; Jaenisch, R
      Nuclear cloning and epigenetic reprogramming of the genome

      SCIENCE
    19. Wakamatsu, Y; Ju, BS; Pristyaznhyuk, I; Niwa, K; Ladygina, T; Kinoshita, M; Araki, K; Ozato, K
      Fertile and diploid nuclear transplants derived from embryonic cells of a small laboratory fish, medaka (Oryzias latipes)

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    20. Amano, T; Tani, T; Kato, Y; Tsunoda, Y
      Mouse cloned from embryonic stem (ES) cells synchronized in metaphase withnocodazole

      JOURNAL OF EXPERIMENTAL ZOOLOGY
    21. Van Reenen, CG; Meuwissen, THE; Hopster, H; Oldenbroek, K; Kruip, TAM; Blokhuis, HJ
      Transgenesis may affect farm animal welfare: A case for systematic risk assessment

      JOURNAL OF ANIMAL SCIENCE
    22. Kang, YK; Koo, DB; Park, JS; Choi, YH; Lee, KK; Han, YM
      Influence of oocyte nuclei on demethylation of donor genome in cloned bovine embryos

      FEBS LETTERS
    23. Reggio, BC; James, AN; Green, HL; Gavin, WG; Behboodi, E; Echelard, Y; Godke, RA
      Cloned transgenic offspring resulting from somatic cell nuclear transfer in the goat: Oocytes derived from both follicle-stimulating hormone-stimulated and nonstimulated abattoir-derived ovaries

      BIOLOGY OF REPRODUCTION
    24. Kuhholzer, B; Hawley, RJ; Lai, L; Kolber-Simonds, D; Prather, RS
      Clonal lines of transgenic fibroblast cells derived from the same fetus result in different development when used for nuclear transfer in pigs

      BIOLOGY OF REPRODUCTION
    25. Kasinathan, P; Knott, JG; Moreira, PN; Burnside, AS; Jerry, DJ; Robl, JM
      Effect of fibroblast donor cell age and cell cycle on development of bovine nuclear transfer embryos in vitro

      BIOLOGY OF REPRODUCTION
    26. Dinnyes, A; Dal, YP; Barber, M; Liu, L; Xu, J; Zhou, PL; Yang, XZ
      Development of cloned embryos from adult rabbit fibroblasts: Effect of activation treatment and donor cell preparation

      BIOLOGY OF REPRODUCTION
    27. Tani, T; Kato, Y; Tsunoda, Y
      Direct exposure of chromosomes to nonactivated ovum cytoplasm is effectivefor bovine somatic cell nucleus reprogramming

      BIOLOGY OF REPRODUCTION
    28. Onat, D; Stahl, W; Sies, H
      Stimulation of gap junctional intercellular communication by thalidomide and thalidomide analogs in human fetal skin fibroblasts (HFFF2) and in rat liver epithelial cells (WB-F344)

      BIOCHEMICAL PHARMACOLOGY
    29. Kuhholzer, B; Brem, G
      Somatic nuclear transfer in livestock species

      ARCHIV FUR TIERZUCHT-ARCHIVES OF ANIMAL BREEDING
    30. Murakami, M; Boediono, A; Perez, O; Ferguson, E; Denniston, RS; Behboodi, E; Godke, RA
      The use of adult bovine skin fibroblasts cultured at different intervals prior to nuclear transfer

      ARCHIV FUR TIERZUCHT-ARCHIVES OF ANIMAL BREEDING
    31. Wobus, AM; Wolf, E; Beier, HM
      Embryonic stem cells and nuclear transfer strategies - Present state and future prospects

      CELLS TISSUES ORGANS
    32. Kent-First, M; First, N
      Getting genes where we want them

      NATURE BIOTECHNOLOGY
    33. Dobrinski, I; Avarbock, MR; Brinster, RL
      Germ cell transplantation from large domestic animals into mouse testes

      MOLECULAR REPRODUCTION AND DEVELOPMENT
    34. Winger, QA; Hill, JR; Shin, TY; Watson, AJ; Kraemer, DC; Westhusin, ME
      Genetic reprogramming of lactate dehydrogenase, citrate synthase, and phosphofructokinase mRNA in bovine nuclear transfer embryos produced using bovine fibroblast cell nuclei

      MOLECULAR REPRODUCTION AND DEVELOPMENT
    35. Kuhholzer, B; Tao, T; Machaty, Z; Hawley, RJ; Greenstein, JL; Day, BN; Prather, RS
      Production of transgenic porcine blastocysts by nuclear transfer

      MOLECULAR REPRODUCTION AND DEVELOPMENT
    36. Cheong, HT; Ikeda, K; Diaz, MAM; Katagiri, S; Takahashi, Y
      Development of reconstituted pig embryos by nuclear transfer of cultured cumulus cells

      REPRODUCTION FERTILITY AND DEVELOPMENT
    37. Wang, YG; Zou, XG; Liu, J; Zhang, JP; Zhang, XC; Lao, WD; Du, MA; Cheng, GX; Cheng, Y; Cheng, JQ; Zhang, SL; Xu, SF
      Cloned goats (Gapra hircus) from foetal fibroblast cell lines

      CHINESE SCIENCE BULLETIN
    38. Nam, YK; Cho, YS; Kim, DS
      Isogenic transgenic homozygous fish induced by artificial parthenogenesis

      TRANSGENIC RESEARCH
    39. Wolf, E; Schernthaner, W; Zakhartchenko, V; Prelle, K; Stojkovic, M; Brem, G
      Transgenic technology in farm animals - progress and perspectives

      EXPERIMENTAL PHYSIOLOGY
    40. Logan, JS
      Prospects for xenotransplantation

      CURRENT OPINION IN IMMUNOLOGY
    41. Lee, CS; Fang, NZ; Koo, DB; Lee, YS; Zheng, GD; Oh, KB; Youn, WS; Han, YM; Kim, SJ; Lim, JH; Shin, ST; Jin, SW; Lee, KS; Ko, JH; Koos, JS; Park, CS; Lee, KS; Yoo, OJ; Lee, KK
      Embryo recovery and transfer for the production of transgenic goats from Korean native strain, Capra hircus aegagrus

      SMALL RUMINANT RESEARCH
    42. Nour, MSM; Takahashi, Y
      In vitro developmental potential of bovine nuclear transfer embryos derived from primary cultured cumulus cells

      JOURNAL OF VETERINARY MEDICAL SCIENCE
    43. Han, YM; Kim, SJ; Park, JS; Park, IY; Kang, YK; Lee, CS; Koo, DB; Lee, TH; Yu, DY; Kim, YH; Lee, KJ; Lee, KK
      Blastocyst viability and generation of transgenic cattle following freezing of in vitro produced, DNA-injected embryos

      ANIMAL REPRODUCTION SCIENCE
    44. Wilmut, I; Young, L; DeSousa, P; King, T
      New opportunities in animal breeding and production - an introductory remark

      ANIMAL REPRODUCTION SCIENCE
    45. Niemann, H; Kues, WA
      Transgenic livestock, premises and promises

      ANIMAL REPRODUCTION SCIENCE
    46. Tsunoda, Y; Kato, Y
      The recent progress on nuclear transfer in mammals

      ZOOLOGICAL SCIENCE
    47. Kishi, M; Itagaki, Y; Takakura, R; Imamura, M; Sudo, T; Yoshinari, M; Tanimoto, M; Yasue, H; Kashima, N
      Nuclear transfer in cattle using colostrum-derived mammary gland epithelial, cells and ear-derived fibroblast cells

      THERIOGENOLOGY
    48. Uhm, SJ; Chung, HM; Kim, C; Shim, H; Kim, NH; Lee, HT; Chung, KS
      In vitro development of porcine enucleated oocytes reconstructed by the transfer of porcine fetal fibroblasts and cumulus cells

      THERIOGENOLOGY
    49. Piedrahita, JA
      Targeted modification of the domestic animal genome

      THERIOGENOLOGY
    50. Polejaeva, IA; Campbell, KHS
      New advances in somatic cell nuclear transfer: Application in transgenesis

      THERIOGENOLOGY
    51. McCreath, KJ; Howcroft, J; Campbell, KHS; Colman, A; Schnieke, AE; King, AJ
      Production of gene-targeted sheep by nuclear transfer from cultured somatic cells (vol 405, pg 1066, 2000)

      NATURE
    52. Suraokar, M; Bradley, A
      Genetics - Targeting sheep

      NATURE
    53. McCreath, KJ; Howcroft, J; Campbell, KHS; Colman, A; Schnieke, AE; Kind, AJ
      Production of gene-targeted sheep by nuclear transfer from cultured somatic cells

      NATURE
    54. Kubota, C; Yamakuchi, H; Todoroki, J; Mizoshita, K; Tabara, N; Barber, M; Yang, XZ
      Six cloned calves produced from adult fibroblast cells after long-term culture

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    55. Tomizuka, K; Shinohara, T; Yoshida, H; Uejima, H; Ohguma, A; Tanaka, S; Sato, K; Oshimura, M; Ishida, I
      Double trans-chromosomic mice: Maintenance of two individual human chromosome fragments containing Ig heavy and kappa loci and expression of fully human antibodies

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    56. Smith, LC; Bordignon, V; Babkine, M; Fecteau, G; Keefer, C
      Benefits and problems with cloning animals

      CANADIAN VETERINARY JOURNAL-REVUE VETERINAIRE CANADIENNE
    57. Hill, JR; Burghardt, RC; Jones, K; Long, CR; Looney, CR; Shin, T; Spencer, TE; Thompson, JA; Winger, QA; Westhusin, ME
      Evidence for placental abnormality as the major cause of mortality in first-trimester somatic cell cloned bovine fetuses

      BIOLOGY OF REPRODUCTION
    58. Daniels, R; Hall, V; Trounson, AO
      Analysis of gene transcription in bovine nuclear transfer embryos reconstructed with granulosa cell nuclei

      BIOLOGY OF REPRODUCTION
    59. Liu, L; Trimarchi, JR; Oldenbourg, R; Keefe, DL
      Increased birefringence in the meiotic spindle provides a new marker for the onset of activation in living oocytes

      BIOLOGY OF REPRODUCTION
    60. Ogura, A; Inoue, K; Ogonuki, N; Noguchi, A; Takano, K; Nagano, R; Suzuki, O; Lee, L; Ishino, F; Matsuda, J
      Production of male cloned mice from fresh, cultured, and cryopreserved immature Sertoli cells

      BIOLOGY OF REPRODUCTION
    61. Miyoshi, K; Taguchi, Y; Sendai, Y; Hoshi, H; Sato, E
      Establishment of a porcine cell line from in vitro-produced blastocysts and transfer of the cells into enucleated oocytes

      BIOLOGY OF REPRODUCTION
    62. Renard, JP
      Nuclear transfer and cellular differentiation: contribution of cloning to the study of stem cells

      BULLETIN DE L ACADEMIE NATIONALE DE MEDECINE
    63. Rojas, E; Herrera, LA; Poirier, LA; Ostrosky-Wegman, P
      Are metals dietary carcinogens?

      MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
    64. Renard, JP; Legouy, E; Chastant, S; Heyman, Y; Vignon, X
      Cloning: present and perspectives

      CONTRACEPTION FERTILITE SEXUALITE
    65. Andreutti, D; Geinoz, A; Gabbiani, G
      Effect of hyaluronic acid on migration, proliferation and alpha-smooth muscle actin expression by cultured rat and human fibroblasts

      JOURNAL OF SUBMICROSCOPIC CYTOLOGY AND PATHOLOGY
    66. Robl, JM
      New life for sperm-mediated transgenesis?

      NATURE BIOTECHNOLOGY
    67. Baguisi, A; Behboodi, E; Melican, DT; Pollock, JS; Destrempes, MM; Cammuso, C; Williams, JL; Nims, SD; Porter, CA; Midura, P; Palacios, MJ; Ayres, SL; Denniston, RS; Hayes, ML; Ziomek, CA; Meade, HM; Godke, RA; Gavin, WG; Overstrom, EW; Echelard, Y
      Production of goats by somatic cell nuclear transfer

      NATURE BIOTECHNOLOGY
    68. Campbell, KHS
      Nuclear transfer in farm animal species

      SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
    69. Evans, MJ; Gurer, C; Loike, JD; Wilmut, I; Schnieke, AE; Schon, EA
      Mitochondrial DNA genotypes in nuclear transfer-derived cloned sheep

      NATURE GENETICS
    70. Colman, A
      Dolly, Polly and other 'ollys': likely impact of cloning technology on biomedical uses of livestock

      GENETIC ANALYSIS-BIOMOLECULAR ENGINEERING
    71. Zakhartchenko, V; Alberio, R; Stojkovic, M; Prelle, K; Schernthaner, W; Stojkovic, P; Wenigerkind, H; Wanke, R; Duchler, M; Steinborn, R; Mueller, M; Brem, G; Wolf, E
      Adult cloning in cattle: Potential of nuclei from a permanent cell line and from primary cultures

      MOLECULAR REPRODUCTION AND DEVELOPMENT
    72. Ito, K; Hirabayashi, M; Ueda, M; Nagao, Y; Kimura, K; Hanada, A; Hochi, S
      Effects of timing of oocyte cryopreservation on in vitro development of nuclear-transferred bovine zygotes

      MOLECULAR REPRODUCTION AND DEVELOPMENT
    73. Corley-Smith, GE; Brandhorst, BP
      Preservation of endangered species and populations: A role for genome banking, somatic cell cloning, and androgenesis?

      MOLECULAR REPRODUCTION AND DEVELOPMENT
    74. Grupen, CG; Verma, PJ; Du, ZT; McIlfatrick, SM; Ashman, RJ; Nottle, MB
      Activation of in vivo- and in vitro-derived porcine oocytes by using multiple electrical pulses

      REPRODUCTION FERTILITY AND DEVELOPMENT
    75. Pintado, B; Gutierrez-Adan, A
      Transgenesis in large domestic species: future development for milk modification

      REPRODUCTION NUTRITION DEVELOPMENT
    76. Solter, D
      Cloning and embryonic stem cells: a new era in human biology and medicine

      CROATIAN MEDICAL JOURNAL
    77. Smidt, D; Niemann, H
      Biotechnology in genetics and reproduction

      LIVESTOCK PRODUCTION SCIENCE
    78. Houdebine, LM
      Gene transfer in animals

      BIOFUTUR
    79. Sun, YJ; Baumer, A
      Nonrandom X inactivation and selection of fragile X full mutation in fetalfibroblasts

      AMERICAN JOURNAL OF MEDICAL GENETICS
    80. Rexroad, CE; Powell, AM
      The ovine uterus as a host for in vitro-produced bovine embryos

      THERIOGENOLOGY
    81. Hill, JR; Roussel, AJ; Cibelli, JB; Edwards, JF; Hooper, NL; Miller, MW; Thompson, JA; Looney, CR; Westhusin, ME; Robl, JM; Stice, SL
      Clinical and pathologic features of cloned transgenic calves and fetuses (13 case studies)

      THERIOGENOLOGY
    82. Wakayama, T; Rodriguez, I; Perry, ACF; Yanagimachi, R; Mombaerts, P
      Mice cloned from embryonic stem cells

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    83. Eyestone, WH; Campbell, KHS
      Nuclear transfer from somatic cells: applications in farm animal species

      JOURNAL OF REPRODUCTION AND FERTILITY
    84. Niwa, K; Ladygina, T; Kinoshita, M; Ozato, K; Wakamatsu, Y
      Transplantation of blastula nuclei to non-enucleated eggs in the medaka, Oryzias latipes

      DEVELOPMENT GROWTH & DIFFERENTIATION
    85. McKinnell, RG; Di Berardino, MA
      The biology of cloning: History and rationale

      BIOSCIENCE
    86. Dominko, T; Mitalipova, M; Haley, B; Beyhan, Z; Memili, E; McKusick, B; First, NL
      Bovine oocyte cytoplasm supports development of embryos produced by nuclear transfer of somatic cell nuclei from various mammalian species

      BIOLOGY OF REPRODUCTION
    87. LIU J; FITZLI D; LIU MY; TSEU I; CANIGGIA I; ROTIN D; POST M
      PDGF-INDUCED GLYCOSAMINOGLYCAN SYNTHESIS IS MEDIATED VIA PHOSPHATIDYLINOSITOL 3-KINASE

      American journal of physiology. Lung cellular and molecular physiology
    88. Zinovieva, N; Lassnig, C; Schams, D; Besenfelder, U; Wolf, E; Muller, S; Frenyo, L; Seregi, J; Muller, M; Brem, O
      Stable production of human insulin-like growth factor 1 (IGF-1) in the milk of hemi- and homozygous transgenic rabbits over several generations

      TRANSGENIC RESEARCH
    89. VEITHEN A; AMYERE M; VANDERSMISSEN P; CUPERS P; COURTOY PJ
      REGULATION OF MACROPINOCYTOSIS IN V-SRC-TRANSFORMED FIBROBLASTS - CYCLIC-AMP SELECTIVELY PROMOTES REGURGITATION OF MACROPINOSOMES

      Journal of Cell Science
    90. CHAN PC; HUFF J
      ARSENIC CARCINOGENESIS IN ANIMALS AND IN HUMANS - MECHANISTIC, EXPERIMENTAL, AND EPIDEMIOLOGIC EVIDENCE

      Environmental carcinogenesis & ecotoxicology reviews
    91. LYNN S; LAI HT; GURR JR; JAN KY
      ARSENITE RETARDS DNA BREAK REJOINING BY INHIBITING DNA LIGATION

      Mutagenesis
    92. AVILACHAVEZ E; TORRESYTORRES N; TOVARPALACIO A
      ZWITTERIONIC AMINO-ACID-TRANSPORT IN MAMMALIAN-CELLS

      Revista de Investigacion Clinica
    93. FREEMARK M; DRISCOLL P; MAASKANT R; PETRYK A; KELLY PA
      ONTOGENY OF PROLACTIN RECEPTORS IN THE HUMAN FETUS IN EARLY GESTATION- IMPLICATIONS FOR TISSUE DIFFERENTIATION AND DEVELOPMENT

      The Journal of clinical investigation
    94. RIPLEY CR; BIENKOWSKI RS
      LOCALIZATION OF PROCOLLAGEN-I IN THE LYSOSOME ENDOSOME SYSTEM OF HUMAN FIBROBLASTS/

      Experimental cell research
    95. BOYCE DE; THOMAS A; HART J; MOORE K; HARDING K
      HYALURONIC-ACID INDUCES TUMOR-NECROSIS-FACTOR-ALPHA PRODUCTION BY HUMAN MACROPHAGES IN-VITRO

      British Journal of Plastic Surgery
    96. YAGER JW; WIENCKE JK
      INHIBITION OF POLY(ADP-RIBOSE) POLYMERASE BY ARSENITE

      Mutation research-reviews in mutation research
    97. HOPKINSON D; SCHEINER P; BARILE FA
      IN-VITRO CYTOTOXICITY TESTING OF POTENTIALLY ACTIVE ANTI-HIV DRUGS WITH CULTURED-CELLS

      ATLA. Alternatives to laboratory animals
    98. MANUSKIATTI W; MAIBACH HI
      HYALURONIC-ACID AND SKIN - WOUND-HEALING AND AGING

      International journal of dermatology
    99. PRICE WA; MOATSSTAATS BM; STILES AD
      INSULIN-LIKE GROWTH-FACTOR-I (IGF-I) REGULATES IGFBP-3 AND IGFBP-4 BYMULTIPLE MECHANISMS IN A549 HUMAN ADENOCARCINOMA CELLS

      American journal of respiratory cell and molecular biology
    100. RUSSELL SB; TRUPIN JS; KENNEDY RZ; RUSSELL JD; DAVIDSON JM
      GLUCOCORTICOID REGULATION OF ELASTIN SYNTHESIS IN HUMAN FIBROBLASTS -DOWN-REGULATION IN FIBROBLASTS FROM NORMAL DERMIS BUT NOT FROM KELOIDS

      Journal of investigative dermatology


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Documento generato il 21/10/20 alle ore 01:38:42