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Chain termination steps in nonribosomal peptide synthetase assembly lines:Directed acyl-S-enzyme breakdown in antibiotic and siderophore biosynthesis
CHEMBIOCHEM
The FIRE3-mediated sterol response of the FAS promoter requires NF-Y/CBF as a coactivator
BIOLOGICAL CHEMISTRY
Regulation of lipid metabolism and gene expression by fenofibrate in hamsters
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
The age-related differences in obese and fatty acid synthase gene expression in white adipose tissue of rat
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
Very-long-chain fatty acid-containing phospholipids accumulate in fatty acid synthase temperature-sensitive mutant strains of the fission yeast Schizosaccharomyces pombe fas2/lsd1
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
Purification and characterization of the fatty acid synthase from Bugula neritina
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
Analysis of the prodiginine biosynthesis gene cluster of Streptomyces coelicolor A3(2): new mechanisms for chain initiation and termination in modular multienzymes
CHEMISTRY & BIOLOGY
Role of type II thioesterases: evidence for removal of short acyl chains produced by aberrant decarboxylation of chain extender units
CHEMISTRY & BIOLOGY
Novel features in a combined polyketide synthase/non-ribosomal peptide synthetase: the myxalamid biosynthetic gene cluster of the myxobacterium Stigmatella aurantiaca Sga15
CHEMISTRY & BIOLOGY
Obesity in mice and men
OBESITY RESEARCH
A trawl through the current nutrition literature
NUTRITION
Intracellular energy signals and dietary calcium: A milky way to the physiologic control of hyperphagia and obesity?
NUTRITION
Androgens stimulate lipogenic gene expression in prostate cancer cells by activation of the sterol regulatory element-binding protein cleavage activating protein/sterol regulatory element binding protein pathway
MOLECULAR ENDOCRINOLOGY
Effects of acetyl-L-carnitine on the formation of patty acid ethyl esters in brain and peripheral organs after short-term ethanol administration in rat
NEUROCHEMICAL RESEARCH
Fatty acid synthase (FAS) expression in human breast cancer cell culture supernatants and in breast cancer patients
CANCER LETTERS
Construction and analysis of mouse strains lacking the ubiquitin ligase UBR1 (E3 alpha) of the N-end rule pathway
MOLECULAR AND CELLULAR BIOLOGY
Candida tropicalis Etr1p and Saccharomyces cerevisiae Ybr026p (Mrf1 ' p), 2-enoyl thioester reductases essential for mitochondrial respiratory competence
MOLECULAR AND CELLULAR BIOLOGY
Increased fatty acid synthase as a therapeutic target in androgen-independent prostate cancer progression
PROSTATE
Polyketide biosynthesis: a millennium review
NATURAL PRODUCT REPORTS
Biochemistry of natural rubber, a vital raw material, emphasizing biosynthetic rate, molecular weight and compartmentalization, in evolutionarily divergent plant species
NATURAL PRODUCT REPORTS
Promoter I of the ovine acetyl-CoA carboxylase-alpha gene: an E-box motif at - 114 in the proximal promoter binds upstream stimulatory factor (USF)-1and USF-2 and acts as an insulin-response sequence in differentiating adipocytes
BIOCHEMICAL JOURNAL
Unfolding and inactivation of fatty acid synthase from chicken liver during urea denaturation
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY
Sterol regulatory element-binding proteins (SREBPs): transcriptional regulators of lipid synthetic genes
PROGRESS IN LIPID RESEARCH
Hepatic de novo lipogenesis after liver transplantation
JOURNAL OF PARENTERAL AND ENTERAL NUTRITION
Increase of lipogenic enzyme mRNA levels in rat white adipose tissue aftermultiple cycles of starvation-refeeding
METABOLISM-CLINICAL AND EXPERIMENTAL
Exercise down-regulates hepatic fatty acid synthase in streptozotocin-treated rats
JOURNAL OF NUTRITION
Regulation of sterol regulatory element-binding proteins by cholesterol flux in CaCo-2 cells
JOURNAL OF LIPID RESEARCH
Insulin deficiency and reduced expression of lipogenic enzymes in cardiomyopathic hamster
JOURNAL OF LIPID RESEARCH
ADD-1/SREBP-1 is a major determinant of tissue differential lipogenic capacity in mammalian and avian species
JOURNAL OF LIPID RESEARCH
Enzymological and radiotracer studies of lipid metabolism in the flight-capable and flightless morphs of the wing-polymorphic cricket, Gryllus firmus
JOURNAL OF INSECT PHYSIOLOGY
Regulation of the glucose-6-phosphatase gene by glucose occurs by transcriptional and post-transcriptional mechanisms - Differential effect of glucose and xylitol
JOURNAL OF BIOLOGICAL CHEMISTRY
Insulin-responsive nuclear proteins facilitate Sp1 interactions with the insulin-like growth factor-I gene
JOURNAL OF BIOLOGICAL CHEMISTRY
Transcriptional regulation of the murine acetyl-CoA synthetase 1 gene through multiple clustered binding sites for sterol regulatory element-binding proteins and a single neighboring site for Sp1
JOURNAL OF BIOLOGICAL CHEMISTRY
Glucose and insulin function through two distinct transcription factors tostimulate expression of lipogenic enzyme genes in liver
JOURNAL OF BIOLOGICAL CHEMISTRY
TNF-alpha inhibits UCP-1 expression in brown adipocytes via ERKs - Opposite effect of p38MAPK
FEBS LETTERS
Fatty acid synthesis in developing leaves of Brassica napus in relation toleaf growth and changes is activity of 3-oxoacyl-ACP reductase
FEBS LETTERS
Cross-talk between the signals hypoxia and glucose at the glucose responseelement of the L-type pyruvate kinase gene
ENDOCRINOLOGY
Sterol regulatory element binding protein-1a regulation of the steroidogenic acute regulatory protein gene
ENDOCRINOLOGY
Two-site ELISA for the quantitative determination of fatty acid synthase
CLINICA CHIMICA ACTA
Intermodular communication in polyketide syntheses: Comparing the role of protein-protein interactions to those in other multidomain proteins
BIOCHEMISTRY
Malonyl-CoA : ACP transacylase from Streptomyces coelicolor has two alternative catalytically active nucleophiles
BIOCHEMISTRY
beta-Ketoacyl-[acyl carrier protein] synthase I of Escherichia coli: Aspects of the condensation mechanism revealed by analyses of mutations in the active site pocket
BIOCHEMISTRY
Effect of atorvastatin, simvastatin, and lovastatin on the metabolism of cholesterol and triacylglycerides in HepG2 cells
BIOCHEMICAL PHARMACOLOGY
Decreased resistin expression in mice with different sensitivities to a high-fat diet
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Green tea epigallocatechin gallate: A natural inhibitor of fatty-acid synthase
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Fatty acid synthase inhibition in human breast cancer cells leads to malonyl-CoA-induced inhibition of fatty acid oxidation and cytotoxicity
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Transcriptional regulation of insulin receptor gene promoter in rat hepatocytes
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Chromosomal localization, expression pattern, and promoter analysis of themouse gene encoding adipocyte-specific secretory protein Acrp30
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Role of Sp1 and Sp3 in the transcriptional regulation of the rat fatty acid synthase gene
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
Immunohistochemical expression of human erythrocyte glucose transporter and fatty acid synthase in infiltrating breast carcinomas and adjacent typical/atypical hyperplastic or normal breast tissue
AJCP. American journal of clinical pathology
Regulation of gene expression by SREBP and SCAP
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
Effect of beta-adrenergic agonist L-644,969 on the impact of the thermal environment on in vitro fatty acid synthesis and lipogenic enzymes in sheep
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY
A novel multidrug efflux transporter gene of the major facilitator superfamily from Candida albicans (FLU1) conferring resistance to fluconazole
MICROBIOLOGY-UK
Lipogenic enzymes fatty acid synthase and acetyl-coenzyme A carboxylase are coexpressed with sterol regulatory element binding protein and Ki-67 in fetal tissues
PEDIATRIC AND DEVELOPMENTAL PATHOLOGY
Immunohistochemical study of fatty acid synthase in ovarian neoplasms
ONCOLOGY REPORTS
Knockout of the regulatory site of 3-ketoacyl-ACP synthase III enhances short- and medium-chain acyl-ACP synthesis
PLANT JOURNAL
In-vivo and in-vitro nutrient-gene interactions
CURRENT OPINION IN LIPIDOLOGY
Nutritional deprivation reduces the transcripts for transcription factors and adipocyte-characteristic proteins in porcine adipocytes
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
The activity of fatty acid synthase of epidermal keratinocytes is regulated in the lower stratum spinousum and the stratum basale by local inflammation rather than by circulating hormones
JOURNAL OF DERMATOLOGICAL SCIENCE
Dependence of rat spot14 promoter activity on NF-Y binding to the invertedCCAAT-element at-100
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
Fatty-acid synthase and human cancer: New perspectives on its role in tumor biology
NUTRITION
Diazoxide down-regulates leptin and lipid metabolizing enzymes in adipose tissue of Zucker rats
FASEB JOURNAL
Expression of porcine adipocyte transcripts during differentiation in vitro and in vivo
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
Are Kupffer cells involved in the metabolic adaptation of the liver to dietary carbohydrates given after fasting?
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
Overexpression of fatty acid synthase in SKBR3 breast cancer cell line is mediated via a transcriptional mechanism
CANCER LETTERS
Molecular aspects of beta-ketoacyl synthase (KAS) catalysis
BIOCHEMICAL SOCIETY TRANSACTIONS
Acyl carrier protein (ACP) inhibition and other differences between beta-ketoacyl synthase (KAS) I and II
BIOCHEMICAL SOCIETY TRANSACTIONS
Biochemical characterization of 3-ketoacyl-acyl carrier protein synthase II from leek epidermis
BIOCHEMICAL SOCIETY TRANSACTIONS
Vanadate restores glucose 6-phosphate in diabetic rats: a mechanism to enhance glucose metabolism
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
Role of reducing co-factors in catalytic reactions of 6-hydroxymellein synthase, a multifunctional polyketide biosynthetic enzyme in carrot cells
PLANT SCIENCE
Unusual arrangement of catalytic domains in head-to-tail associated homodimer of 6-hydroxymellein synthase, a multifunctional polyketide biosyntheticenzyme
PLANT SCIENCE
Identification of a novel FAS/ER-alpha fusion transcript expressed in human cancer cells
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION
Molecular analysis of a Type I fatty acid synthase in Cryptosporidium parvum
MOLECULAR AND BIOCHEMICAL PARASITOLOGY
Synthesis, structure and properties of polyhydroxyalkanoates: biological polyesters
PROGRESS IN POLYMER SCIENCE
Swinging arms and swinging domains in multifunctional enzymes: Catalytic machines for multistep reactions
ANNUAL REVIEW OF BIOCHEMISTRY
The expression of fatty acid synthase (FASE) is an early event in the development and progression of squamous cell carcinoma of the lung
HUMAN PATHOLOGY
Activation of promoters for cellular lipogenic genes by hepatitis B virus large surface protein
VIROLOGY
Acyl-CoA hydrolysis by the high molecular weight protein 1 subunit of yersiniabactin synthetase: Mutational evidence for a cascade of four acyl-enzyme intermediates during hydrolytic editing
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Chinese green tea lowers cholesterol level through an increase in fecal lipid excretion
LIFE SCIENCES
Regulation of hepatic Delta-6 desaturase expression and its role in the polyunsaturated fatty acid inhibition of fatty acid synthase gene expression in mice
JOURNAL OF NUTRITION
Regulation of the fatty acid synthase promoter by insulin
JOURNAL OF NUTRITION
Copper deficiency induces hepatic fatty acid synthase gene transcription in rats by increasing the nuclear content of mature sterol regulatory element binding protein 1
JOURNAL OF NUTRITION
Relationship between human adipose tissue agouti and fatty acid synthase (FAS)
JOURNAL OF NUTRITION
Mammary lipogenic enzyme activity, trans fatty acids and conjugated linoleic acids are altered in lactating dairy cows fed a milk fat-depressing diet
JOURNAL OF NUTRITION
Thioesterase domain of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase: Alteration of stereospecificity by site-directed mutagenesis
JOURNAL OF MOLECULAR BIOLOGY
Fatty acid synthase is expressed mainly in adult hormone-sensitive cells or cells with high lipid metabolism and in proliferating fetal cells
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
Radicicol binds and inhibits mammalian ATP citrate lyase
JOURNAL OF BIOLOGICAL CHEMISTRY
Glucose regulation of gene transcription
JOURNAL OF BIOLOGICAL CHEMISTRY
Acetyl-CoA carboxylase and fatty acid synthase activity and immunodetectable protein in adipose tissues of ruminants: Effect of temperature and feeding level
JOURNAL OF ANIMAL SCIENCE
Expression of porcine transcription factors and genes related to fatty acid metabolism in different tissues and genetic populations
JOURNAL OF ANIMAL SCIENCE
Effect of feed restriction on adipose tissue transcript concentrations in genetically lean and obese pigs
JOURNAL OF ANIMAL SCIENCE
Sterol regulatory element-binding protein-1 participates in the regulationof fatty acid synthase expression in colorectal neoplasia
EXPERIMENTAL CELL RESEARCH
A novel function of yeast fatty acid synthase - Subunit alpha is capable of self-pantetheinylation
EUROPEAN JOURNAL OF BIOCHEMISTRY
A novel NADPH : diamide oxidoreductase activity in Arabidopsis thaliana P1zeta-crystallin
EUROPEAN JOURNAL OF BIOCHEMISTRY
Lipases provide a new mechanistic model for polyhydroxybutyrate (PHB) synthases: Characterization of the functional residues in Chromatium vinosum PHB synthase
BIOCHEMISTRY
Mutation of the nucleophilic elbow of the Lux-specific thioesterase from Vibrio harveyi
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Progestins and androgens increase expression of Spot 14 in T47-D breast tumor cells
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
New placental factors in early pregnancy
FETUS AS A PATIENT
Fatty acid synthase expression in Japanese breast carcinoma patients
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
Seasonal and diel transitions in physiology and behavior in the migratory dark-eyed junco
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR AND INTEGRATIVE PHYSIOLOGY