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La ricerca find articoli where soggetti phrase all words 'ERYTHROMYCIN BIOSYNTHESIS' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 54 riferimenti
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    1. Mendes, MV; Recio, E; Fouces, R; Luiten, R; Martin, JF; Aparicio, JF
      Engineered biosynthesis of novel polyenes: a pimaricin derivative producedby targeted gene disruption in Streptomyces natalensis

      CHEMISTRY & BIOLOGY
    2. Holzbaur, IE; Ranganathan, A; Thomas, IP; Kearney, DJA; Reather, JA; Rudd, BAM; Staunton, J; Leadlay, PF
      Molecular basis of Celmer's rules: role of the ketosynthase domain in epimerisation and demonstration that ketoreductase domains can have altered product specificity with unnatural substrates

      CHEMISTRY & BIOLOGY
    3. Heathcole, ML; Staunton, J; Leadlay, PF
      Role of type II thioesterases: evidence for removal of short acyl chains produced by aberrant decarboxylation of chain extender units

      CHEMISTRY & BIOLOGY
    4. Cornish, K
      Biochemistry of natural rubber, a vital raw material, emphasizing biosynthetic rate, molecular weight and compartmentalization, in evolutionarily divergent plant species

      NATURAL PRODUCT REPORTS
    5. Zhang, QB; Sherman, DH
      Isolation and structure determination of novamethymycin, a new bioactive metabolite of the methymycin biosynthetic pathway in Streptomyces venezuelae

      JOURNAL OF NATURAL PRODUCTS
    6. Cupp-Vickery, JR; Garcia, C; Hofacre, A; McGee-Estrada, K
      Ketoconazole-induced conformational changes in the active site of cytochrome P450eryF

      JOURNAL OF MOLECULAR BIOLOGY
    7. Haines, DC; Tomchick, DR; Machius, M; Peterson, JA
      Pivotal role of water in the mechanism of P450BM-3

      BIOCHEMISTRY
    8. Wu, N; Tsuji, SY; Cane, DE; Khosla, C
      Assessing the balance between protein-protein interactions and enzyme-substrate interactions in the channeling of intermediates between polyketide synthase modules

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    9. Aparicio, JF; Fouces, R; Mendes, MV; Olivera, N; Martin, JF
      A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricinin Streptomyces natalensis

      CHEMISTRY & BIOLOGY
    10. Gaisser, S; Reather, J; Wirtz, G; Kellenberger, L; Staunton, JU; Leadlay, PF
      A defined system for hybrid macrolide biosynthesis in Saccharopolyspora erythraea

      MOLECULAR MICROBIOLOGY
    11. Lal, R; Kumari, R; Kaur, H; Khanna, R; Dhingra, N; Tuteja, D
      Regulation and manipulation of the gene clusters encoding type-I PKSs

      TRENDS IN BIOTECHNOLOGY
    12. Aguirrezabalaga, I; Olano, C; Allende, N; Rodriguez, L; Brana, AF; Mendez, C; Salas, JA
      Identification and expression of genes involved in biosynthesis of L-oleandrose and its intermediate L-olivose in the oleandomycin producer Streptomyces antibioticus

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    13. Cupp-Vickery, J; Anderson, R; Hatziris, Z
      Crystal structures of ligand complexes of P450eryF exhibiting homotropic cooperativity

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    14. Doumith, M; Weingarten, P; Wehmeier, UF; Salah-Bey, K; Benhamou, B; Capdevila, C; Michel, JM; Piepersberg, W; Raynal, MC
      Analysis of genes involved in 6-deoxyhexose biosynthesis and transfer in Saccharopolyspora erythraea

      MOLECULAR AND GENERAL GENETICS
    15. Xiang, H; Tschirret-Guth, RA; de Montellano, PRO
      An A245T mutation conveys on cytochrome P450(eryF) the ability to oxidize alternative substrates

      JOURNAL OF BIOLOGICAL CHEMISTRY
    16. Shah, S; Xue, Q; Tang, L; Carney, JR; Betlach, M; McDaniel, R
      Cloning, characterization and heterologous expression of a polyketide synthase and P-450 oxidase involved in the biosynthesis of the antibiotic oleandomycin

      JOURNAL OF ANTIBIOTICS
    17. Bentley, R; Bennett, JW
      Constructing polyketides: From collie to combinatorial biosynthesis

      ANNUAL REVIEW OF MICROBIOLOGY
    18. Khosla, C; Gokhale, RS; Jacobsen, JR; Cane, DE
      Tolerance and specificity of polyketide synthases

      ANNUAL REVIEW OF BIOCHEMISTRY
    19. de Groot, MJ; Ackland, MJ; Horne, VA; Alex, AA; Jones, BC
      Novel approach to predicting P450-mediated drug metabolism: Development ofa combined protein and pharmacophore model for CYP2D6

      JOURNAL OF MEDICINAL CHEMISTRY
    20. Lomovskaya, N; Otten, SL; Doi-Katayama, Y; Fonstein, L; Liu, XC; Takatsu, T; Inventi-Solari, A; Filippini, S; Torti, F; Colombo, AL; Hutchinson, CR
      Doxorubicin overproduction in Streptomyces peucetius: Cloning and characterization of the dnrU ketoreductase and dnrV genes and the doxA cytochrome P-450 hydroxylase gene

      JOURNAL OF BACTERIOLOGY
    21. English, RS; Lampel, JS; Vanden Boom, TJ
      Transformation of Saccharopolyspora erythraea by electroporation of germinating spores: construction of propionyl Co-A carboxylase mutants

      JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
    22. XUE YQ; WILSON D; ZHAO LS; LIU HW; SHERMAN DH
      HYDROXYLATION OF MACROLACTONES YC-17 AND NARBOMYCIN IS MEDIATED BY THE PIKC-ENCODED CYTOCHROME-P450 IN STREPTOMYCES-VENEZUELAE

      Chemistry & biology
    23. Weissman, KJ; Bycroft, M; Cutter, AL; Hanefeld, U; Frost, EJ; Timoney, MC; Harris, R; Handa, S; Roddis, M; Staunton, J; Leadlay, PF
      Evaluating precursor-directed biosynthesis towards novel erythromycins through in vitrostudies on a bimodular polyketide synthase

      CHEMISTRY & BIOLOGY
    24. QUIROS LM; AGUIRREZABALAGA I; OLANO C; MENDEZ C; SALAS JA
      2 GLYCOSYLTRANSFERASES AND A GLYCOSIDASE ARE INVOLVED IN OLEANDOMYCINMODIFICATION DURING ITS BIOSYNTHESIS BY STREPTOMYCES-ANTIBIOTICUS

      Molecular microbiology
    25. STASSI D; POST D; SATTER M; JACKSON M; MAINE G
      A GENETICALLY-ENGINEERED STRAIN OF SACCHAROPOLYSPORA-ERYTHRAEA THAT PRODUCES 6,12-DIDEOXYERYTHROMYCIN A AS THE MAJOR FERMENTATION PRODUCT

      Applied microbiology and biotechnology
    26. XUE YQ; ZHAO LS; LIU HW; SHERMAN DH
      A GENE-CLUSTER FOR MACROLIDE ANTIBIOTIC BIOSYNTHESIS IN STREPTOMYCES-VENEZUELAE - ARCHITECTURE OF METABOLIC DIVERSITY

      Proceedings of the National Academy of Sciences of the United Statesof America
    27. OLANO C; RODRIGUEZ AM; MICHEL JM; MENDEZ C; RAYNAL MC; SALAS JA
      ANALYSIS OF A STREPTOMYCES-ANTIBIOTICUS CHROMOSOMAL REGION INVOLVED IN OLEANDOMYCIN BIOSYNTHESIS, WHICH ENCODES 2 GLYCOSYLTRANSFERASES RESPONSIBLE FOR GLYCOSYLATION OF THE MACROLACTONE RING

      MGG. Molecular & general genetics
    28. FERNANDEZ E; WEISSBACH U; REILLO CS; BRANA AF; MENDEZ C; ROHR J; SALAS JA
      IDENTIFICATION OF 2 GENES FROM STREPTOMYCES-ARGILLACEUS ENCODING GLYCOSYLTRANSFERASES INVOLVED IN TRANSFER OF A DISACCHARIDE DURING BIOSYNTHESIS OF THE ANTITUMOR DRUG MITHRAMYCIN

      Journal of bacteriology
    29. BRUNTNER C; BORMANN C
      THE STREPTOMYCES-TENDAE TU901 L-LYSINE 2-AMINOTRANSFERASE CATALYZES THE INITIAL REACTION IN NIKKOMYCIN-D BIOSYNTHESIS

      European journal of biochemistry
    30. BETLACH MC; KEALEY JT; BETLACH MC; ASHLEY GW; MCDANIEL R
      CHARACTERIZATION OF THE MACROLIDE P-450 HYDROXYLASE FROM STREPTOMYCES-VENEZUELAE WHICH CONVERTS NARBOMYCIN TO PICROMYCIN

      Biochemistry (Easton)
    31. CANE DE; GRAZIANI EI
      METHAMYCIN BIOSYNTHESIS - ISOLATION OF P450 MONOOXYGENASE ACTIVITY INA CELL-FREE SYSTEM FROM STREPTOMYCES-VENEZUELAE

      Journal of the American Chemical Society
    32. CHUCK JA; MCPHERSON M; HUANG H; JACOBSEN JR; KHOSLA C; CANE DE
      MOLECULAR RECOGNITION OF DIKETIDE SUBSTRATES BY A BETA-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE DOMAIN WITHIN A BIMODULAR POLYKETIDE SYNTHASE

      Chemistry & biology
    33. CUPPVICKERY JR; POULOS TL
      STRUCTURE OF CYTOCHROME P450ERYF - SUBSTRATE, INHIBITORS, AND MODEL COMPOUNDS BOUND IN THE ACTIVE-SITE

      Steroids
    34. KATZ L
      MANIPULATION OF MODULAR POLYKETIDE SYNTHESES

      Chemical reviews
    35. KHOSLA C
      HARNESSING THE BIOSYNTHETIC POTENTIAL OF MODULAR POLYKETIDE SYNTHASES

      Chemical reviews
    36. YANG KQ; HAN L; AYER SW; VINING LC
      ACCUMULATION OF THE ANGUCYCLINE ANTIBIOTIC RABELOMYCIN AFTER DISRUPTION OF AN OXYGENASE GENE IN THE JADOMYCIN-B BIOSYNTHETIC GENE-CLUSTER OF STREPTOMYCES-VENEZUELAE

      Microbiology
    37. BEDFORD D; JACOBSEN JR; LUO GL; CANE DE; KHOSLA C
      A FUNCTIONAL CHIMERIC MODULAR POLYKETIDE SYNTHASE GENERATED VIA DOMAIN REPLACEMENT

      Chemistry & biology
    38. DEGROOT MJ; VERMEULEN NPE; KRAMER JD; VANACKER FAA; DENKELDER GMDO
      A 3-DIMENSIONAL PROTEIN MODEL FOR HUMAN CYTOCHROME-P450 2D6 BASED ON THE CRYSTAL-STRUCTURES OF P450-101, P450-102, AND P450-108

      Chemical research in toxicology
    39. MOLNAR I; APARICIO JF; HAYDOCK SF; KHAW LE; SCHWECKE T; KONIG A; STAUNTON J; LEADLAY PF
      ORGANIZATION OF THE BIOSYNTHETIC GENE-CLUSTER FOR RAPAMYCIN IN STREPTOMYCES-HYGROSCOPICUS - ANALYSIS OF GENES FLANKING THE POLYKETIDE SYNTHASE

      Gene
    40. BOWER S; PERKINS JB; YOCUM RR; HOWITT CL; RAHAIM P; PERO J
      CLONING, SEQUENCING, AND CHARACTERIZATION OF THE BACILLUS-SUBTILIS BIOTIN BIOSYNTHETIC OPERON

      Journal of bacteriology
    41. TSUKAMOTO N; CHUCK JA; LUO GL; KAO CM; KHOSLA C; CANE DE
      6-DEOXYERYTHRONOLIDE-B SYNTHASE 1 IS SPECIFICALLY ACYLATED BY A DIKETIDE INTERMEDIATE AT THE BETA-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE DOMAIN OF MODULE-2

      Biochemistry
    42. FILIPPINI S; SOLINAS MM; BREME U; SCHLUTER MB; GABELLINI D; BIAMONTI G; COLOMBO AL; GAROFANO L
      STREPTOMYCES PEUCETIUS DAUNORUBICIN BIOSYNTHESIS GENE, DNRF - SEQUENCE AND HETEROLOGOUS EXPRESSION

      Microbiology
    43. MOHRLE V; ROOS U; BORMANN C
      IDENTIFICATION OF CELLULAR PROTEINS INVOLVED IN NIKKOMYCIN PRODUCTIONIN STREPTOMYCES-TENDAE TU901

      Molecular microbiology
    44. ARISAWA A; TSUNEKAWA H; OKAMURA K; OKAMOTO R
      NUCLEOTIDE-SEQUENCE ANALYSIS OF THE CARBOMYCIN BIOSYNTHETIC GENES INCLUDING THE 3-O-ACYLTRANSFERASE GENE FROM STREPTOMYCES THERMOTOLERANS

      Bioscience, biotechnology, and biochemistry
    45. ROHR J
      COMBINATORIAL BIOSYNTHESIS - AN APPROACH IN THE NEAR FUTURE

      Angewandte Chemie, International Edition in English
    46. BIBB MJ; WHITE J; WARD JM; JANSSEN GR
      THE MESSENGER-RNA FOR THE 23S RIBOSOMAL-RNA METHYLASE ENCODED BY THE ERME GENE OF SACCHAROPOLYSPORA-ERYTHRAEA IS TRANSLATED IN THE ABSENCE OF A CONVENTIONAL RIBOSOME-BINDING SITE

      Molecular microbiology
    47. MERSONDAVIES LA; CUNDLIFFE E
      ANALYSIS OF 5 TYLOSIN BIOSYNTHETIC GENES FROM THE TYIIBA REGION OF THE STREPTOMYCES-FRADIAE GENOME

      Molecular microbiology
    48. INOUYE M; SUZUKI H; TAKADA Y; MUTO N; HORINOUCHI S; BEPPU T
      A GENE ENCODING MYCINAMICIN-III O-METHYLTRANSFERASE FROM MICROMONOSPORA-GRISEORUBIDA

      Gene
    49. LIU HW; THORSON JS
      PATHWAYS AND MECHANISMS IN THE BIOGENESIS OF NOVEL DEOXYSUGARS BY BACTERIA

      Annual review of microbiology
    50. INOUYE M; TAKADA Y; MUTO N; BEPPU T; HORINOUCHI S
      CHARACTERIZATION AND EXPRESSION OF A P-450-LIKE MYCINAMICIN BIOSYNTHESIS GENE USING A NOVEL MICROMONOSPORA ESCHERICHIA-COLI SHUTTLE COSMID VECTOR

      MGG. Molecular & general genetics
    51. KATZ L; DONADIO S
      POLYKETIDE SYNTHESIS - PROSPECTS FOR HYBRID ANTIBIOTICS

      Annual review of microbiology
    52. DECKER H; MOTAMEDI H; HUTCHINSON CR
      NUCLEOTIDE-SEQUENCES AND HETEROLOGOUS EXPRESSION OF TCMG AND TCMP, BIOSYNTHETIC GENES FOR TETRACENOMYCIN-C IN STREPTOMYCES-GLAUCESCENS

      Journal of bacteriology
    53. MADDURI K; TORTI F; COLOMBO AL; HUTCHINSON CR
      CLONING AND SEQUENCING OF A GENE ENCODING CARMINOMYCIN 4-O-METHYLTRANSFERASE FROM STREPTOMYCES-PEUCETIUS AND ITS EXPRESSION IN ESCHERICHIA-COLI

      Journal of bacteriology
    54. THORSON JS; LO SF; LIU HW; HUTCHINSON CR
      BIOSYNTHESIS OF 3,6-DIDEOXYHEXOSES - NEW MECHANISTIC REFLECTIONS UPON2,6-DIDEOXY, 4,6-DIDEOXY, AND AMINO SUGAR CONSTRUCTION

      Journal of the American Chemical Society


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Documento generato il 26/01/21 alle ore 00:57:22