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La ricerca find articoli where soggetti phrase all words 'ERECTILE DYSFUNCTION' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 867 riferimenti
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    1. Keegan, A; Cotter, MA; Cameron, NE
      Corpus cavernosum dysfunction in diabetic rats: effects of combined alpha-lipoic acid and gamma-linolenic acid treatment

      DIABETES-METABOLISM RESEARCH AND REVIEWS
    2. Chancellor, MB; Yoshimura, N; Pruchnic, R; Huard, J
      Gene therapy strategies for urological dysfunction

      TRENDS IN MOLECULAR MEDICINE
    3. Green, JSA; Holden, STR; Ingram, P; Bose, P; St George, DP; Bowsher, WG
      An investigation of erectile dysfunction in Gwent, Wales

      BJU INTERNATIONAL
    4. Seo, KK; Kim, SC; Jun, IO; Oh, MM; Lee, MY
      Synergistic effects of sildenafil on relaxation of rabbit and rat cavernosal smooth muscles when combined with various vasoactive agents

      BJU INTERNATIONAL
    5. Kawanishi, Y; Lee, KS; Kimura, K; Kojima, K; Yamamoto, A; Numata, A
      Feasibility of multi-slice computed tomography in the diagnosis of arteriogenic erectile dysfunction

      BJU INTERNATIONAL
    6. Kawanishi, Y; Lee, KS; Kimura, K; Kojima, K; Yamamoto, A; Numata, A
      Effect of radical retropubic prostatectomy on erectile function, evaluatedbefore and after surgery using colour Doppler ultrasonography and nocturnal penile tumescence monitoring

      BJU INTERNATIONAL
    7. Baniel, J; Israilov, S; Segenreich, E; Livne, PM
      Comparative evaluation of treatments for erectile dysfunction in patients with prostate cancer after radical retropubic prostatectomy

      BJU INTERNATIONAL
    8. Sairam, K; Kulinskaya, E; Boustead, GB; Hanbury, DC; McNicholas, TA
      Prevalence of undiagnosed diabetes mellitus in male erectile dysfunction

      BJU INTERNATIONAL
    9. Osterloh, I; Hargreaves, R
      Editor's comment on: 'Press release: Further research supports Viagra (TM)safety profile'

      BJU INTERNATIONAL
    10. Williams, G
      Editor's comment on: 'Press release: Further research supports Viagra (TM)safety profile' - Reply

      BJU INTERNATIONAL
    11. Souverein, PC; Egberts, ACG; Sturkenboom, MCJM; Meuleman, EJH; Leufkens, HGM; Urquhart, J
      The Dutch cohort of sildenafil users: baseline characteristics

      BJU INTERNATIONAL
    12. Cartledge, JJ; Eardley, I; Morrison, JFB
      Nitric oxide-mediated corpus cavernosal smooth muscle relaxation is impaired in ageing and diabetes

      BJU INTERNATIONAL
    13. Cartledge, JJ; Eardley, I; Morrison, JFB
      Advanced glycation end-products are responsible for the impairment of corpus cavernosal smooth muscle relaxation seen in diabetes

      BJU INTERNATIONAL
    14. Ayan, S; Sarioglu, Y; Yildirim, S; Gokce, G; Bagcivan, I
      Relaxation induced by omeprazole does not change in diabetic rabbit corpuscavernosum

      BJU INTERNATIONAL
    15. Meuleman, E; Cuzin, B; Opsomer, RJ; Hartmann, U; Bailey, MJ; Maytom, MC; Smith, MD; Osterloh, IH
      A dose-escalation study to assess the efficacy and safety of sildenafil citrate in men with erectile dysfunction

      BJU INTERNATIONAL
    16. Khan, MA; Thompson, CS; Jeremy, JY; Mumtaz, FH; Mikhailidis, P; Morgan, RJ
      The effect of superoxide dismutase on nitric oxide-mediated and electricalfield-stimulated diabetic rabbit cavernosal smooth muscle relaxation

      BJU INTERNATIONAL
    17. Kim, DS; Choi, SI; Lee, HS; Park, JK; Yi, HK
      Determination of human angiotensin converting enzyme (ACE) gene polymorphisms in erectile dysfunction: Frequency differences of ACE gene polymorphisms according to the method of analysis

      CLINICAL CHEMISTRY AND LABORATORY MEDICINE
    18. Liaw, J; Chang, TW
      Determination of transdermal sildenafil in nude mouse skin by reversed-phase high-performance liquid chromatography

      JOURNAL OF CHROMATOGRAPHY B
    19. Jeong, CK; Lee, HY; Jang, MS; Kim, WB; Lee, HS
      Narrowbore high-performance liquid chromatography for the simultaneous determination of sildenafil and its metabolite UK-103,320 in human plasma using column switching

      JOURNAL OF CHROMATOGRAPHY B
    20. Jackson, G
      Phosphodiesterase 5 inhibition: Effects on the coronary vasculature

      INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
    21. Sadovsky, R; Miller, T; Moskowitz, M; Hackett, G
      Three-year update of sildenafil citrate (viagra((R))) efficacy and safety

      INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
    22. Goldmeier, D
      Female low sexual desire and sexually transmitted infections

      SEXUALLY TRANSMITTED INFECTIONS
    23. Biering-Sorensen, F; Sonksen, J
      Sexual function in spinal cord lesioned men

      SPINAL CORD
    24. Ide, M; Fugl-Meyer, AR
      Life satisfaction in persons with spinal cord injury: a comparative investigation between Sweden and Japan

      SPINAL CORD
    25. Ramos, AS; Vidal, J; Jauregui, ML; Barrera, M; Recio, C; Giner, M; Toribio, L; Salvador, S; Sanmartin, A; de la Fuente, M; Santos, JF; de Juan, FJ; Moraleda, S; Mendez, JL; Ramirez, L; Casado, RM
      Efficacy, safety and predictive factors of therapeutic success with sildenafil for erectile dysfunction in patients with different spinal cord injuries

      SPINAL CORD
    26. Fricker, J
      The rise and fall of Viagra

      DRUG DISCOVERY TODAY
    27. Yang, CC; Bowen, JD; Kraft, GH; Uchio, EM; Kromm, BG
      Physiologic studies of male sexual dysfunction in multiple sclerosis

      MULTIPLE SCLEROSIS
    28. Lundberg, PO; Ertekin, C; Ghezzi, A; Swash, M; Vodusek, D; de Keyser, J; Schmidt, G; Stien, R
      Neurosexology - Guidelines for neurologists

      EUROPEAN JOURNAL OF NEUROLOGY
    29. Alexopoulou, O; Jamart, J; Maiter, D; Hermans, MP; De Hertogh, R; De Nayer, P; Buysschaert, M
      Erectile dysfunction and lower androgenicity in type 1 diabetic patients

      DIABETES & METABOLISM
    30. Mitrany, D
      Lifestyle drugs - Determining their value and who should pay

      PHARMACOECONOMICS
    31. Bartlik, B; Goldstein, MZ
      Practical geriatrics - Men's sexual health after midlife

      PSYCHIATRIC SERVICES
    32. Cohen, JS
      Comparison of FDA reports of patient deaths associated with sildenafil andwith injectable alprostadil

      ANNALS OF PHARMACOTHERAPY
    33. Cohen, JS
      Is the sildenafil product information adequate to facilitate informed therapeutic decisions?

      ANNALS OF PHARMACOTHERAPY
    34. Ojha, K; Nargund, V; Nargund, G
      Emergency sperm extraction for transient erectile dysfunction prior to assisted conception

      JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
    35. Beal, K; Mears, JG
      Penile lymphoma following local injections for erectile dysfunction

      LEUKEMIA & LYMPHOMA
    36. Rini, BI; Small, EJ
      An update on prostate cancer

      CURRENT OPINION IN ONCOLOGY
    37. Aversa, A; Fabbri, A
      New oral agents for erectile dysfunction: what is changing in our practice?

      ASIAN JOURNAL OF ANDROLOGY
    38. Xu, ZS; Fu, QG; Zhao, ST; Liu, HN
      Effect of diabetes and insulin treatment on nitric oxide synthase content in rat corpus cavernosum

      ASIAN JOURNAL OF ANDROLOGY
    39. Zhu, GY; Shen, Y
      Sympathetic skin response: a new test to diagnose erectile dysfunction

      ASIAN JOURNAL OF ANDROLOGY
    40. Kim, DK; Ryu, DH; Lee, N; Lee, JY; Kim, JS; Lee, S; Choi, JY; Ryu, JH; Kim, NH; Im, GJ; Choi, WS; Kim, TK
      Synthesis and phosphodiesterase 5 inhibitory activity of new 5-phenyl-1,6-dihydro-7H-pyrazolo[4,3-d] pyrimidin-7-one derivatives containing an N-acylamido group on a phenyl ring

      BIOORGANIC & MEDICINAL CHEMISTRY
    41. Kim, DK; Lee, N; Lee, JY; Ryu, DH; Kim, JS; Lee, SH; Choi, JY; Chang, K; Kim, YT; Im, GJ; Choi, WS; Kim, TK; Ryu, JH; Kim, NH; Lee, K
      Synthesis and phosphodiesterase 5 inhibitory activity of novel phenyl ringmodified sildenafil analogues

      BIOORGANIC & MEDICINAL CHEMISTRY
    42. Kim, DK; Lee, JY; Lee, N; Ryu, DH; Kim, JS; Lee, S; Choi, JY; Ryu, JH; Kim, NH; Im, GJ; Choi, WS; Kim, TK
      Synthesis and phosphodiesterase inhibitory activity of new sildenafil analogues containing a carboxylic acid group in the 5 '-sulfonamide moiety of aphenyl ring

      BIOORGANIC & MEDICINAL CHEMISTRY
    43. Giuliano, F; Pena, BM; Mishra, A; Smith, MD
      Efficacy results and quality-of-life measures in men receiving sildenafil citrate for the treatment of erectile dysfunction

      QUALITY OF LIFE RESEARCH
    44. Bi, YZ; Stoy, P; Adam, L; He, B; Krupinski, J; Normandin, D; Pongrac, R; Seliger, L; Watson, A; Macor, JE
      The discovery of novel, potent and selective PDE5 inhibitors

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    45. Burls, A; Gold, L; Clark, W
      Systematic review of randomised controlled trials of sildenafil (Viagra (R)) in the treatment of male erectile dysfunction

      BRITISH JOURNAL OF GENERAL PRACTICE
    46. Lue, TF
      Neurogenic erectile dysfunction

      CLINICAL AUTONOMIC RESEARCH
    47. Steers, W; Guay, AT; Leriche, A; Gingell, C; Hargreave, TB; Wright, PJ; Price, DE; Feldman, RA
      Assessment of the efficacy and safety of Viagra (R) (sildenafil citrate) in men with erectile dysfunction during long-term treatment

      INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
    48. Sommer, F; Obenaus, K; Engelmann, U
      Creative-dynamic image synthesis: a useful addition to the treatment options for impotence

      INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
    49. Burchardt, M; Burchardt, T; Anastasiadis, AG; Kiss, AJ; Shabsigh, A; de La Taille, A; Pawar, RV; Baer, L; Shabsigh, R
      Erectile dysfunction is a marker for cardiovascular complications and psychological functioning in men with hypertension

      INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
    50. Rhoden, EL; Teloken, C; Ting, HY; Lucas, ML; da Ros, CT; Souto, CAV
      Prevalence of Peyronie's disease in men over 50-y-old from Southern Brazil

      INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
    51. Kawanishi, Y; Kishimoto, T; Kimura, K; Yamaguchi, K; Nakatuji, H; Kojima, K; Yamamoto, A; Numata, A
      Spring balance evaluation of the ischiocavernosus muscle

      INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
    52. Marceau, L; Kleinman, K; Goldstein, I; McKinlay, J
      Does bicycling contribute to the risk of erectile dysfunction? Results from the Massachusetts Male Aging Study (MMAS)

      INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
    53. Hatzichristou, DG; Apostolidis, A; Tzortzis, V; Hatzimouratidis, K; Kouvelas, D
      Effects of oral phentolamine, taken before sleep, on nocturnal erectile activity: a double-blind, placebo-controlled, crossover study

      INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
    54. Speel, TGW; Bleumer, I; Diemont, WL; van der Maas, MC; Wijkstra, H; Meuleman, EJ
      The value of sildenafil as mode of stimulation in pharmaco-penile duplex ultrasonography

      INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
    55. Porst, H; Rosen, R; Padma-Nathan, H; Goldstein, I; Giuliano, F; Ulbrich, E; Bandel, T
      The efficacy and tolerability of vardenafil, a new, oral, selective phosphodiesterase type 5 inhibitor, in patients with erectile dysfunction: the first at-home clinical trial

      INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
    56. Ku, JH; Song, YS; Kim, ME; Lee, NK; Park, YH
      Is there a role of radial rigidity in the evaluation of erectile dysfunction?

      INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
    57. Wingard, CJ; Lewis, R; Mills, TM
      Erection and NO override the vasoconstrictive effect of alpha-adrenergic stimulation in the rat penile vasculature

      INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
    58. Chen, KK; Hsieh, JT; Huang, ST; Jiaan, DBP; Lin, JSN; Wang, CJ
      ASSESS-3*: A randomised, double-blind, flexible-dose clinical trial of theefficacy and safety of oral sildenafil in the treatment of men with erectile dysfunction in Taiwan

      INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
    59. Bischoff, E; Schneider, K
      A conscious-rabbit model to study vardenafil hydrochloride and other agents that influence penile erection

      INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
    60. Hsieh, GC; Kolasa, T; Sullivan, JP; Brioni, JD
      Dual mechanism of action of nicorandil on rabbit corpus cavernosal smooth muscle tone

      INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
    61. Bischoff, E
      Rabbits as models for impotence research

      INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
    62. Choppin, A; Blue, DR; Hegde, SS; Gennevois, D; McKinnon, SA; Mokatrin, A; Bivalacqua, TJ; Hellstrom, WJG
      Evaluation of oral Ro70-0004/003, an alpha(1A)-adrenoceptor antagonist, inthe treatment of male erectile dysfunction

      INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
    63. Richter, S; Vardi, Y; Ringel, A; Shalev, M; Nissenkorn, I
      Intracavernous injections: still the gold standard for treatment of erectile dysfunction in elderly men

      INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
    64. Johri, AM; Heaton, JPW; Morales, A
      Severe erectile dysfunction is a marker for hyperprolactinemia

      INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
    65. Chitaley, K; Webb, RC; Mills, TM
      RhoA/Rho-kinase: a novel player in the regulation of penile erection

      INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
    66. Kaiser, T; Jost, WH; Osterhage, J; Derouet, H; Schimrigk, K
      Penile and perianal pudendal nerve somatosensory evoked potentials in the diagnosis of erectile dysfunction

      INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
    67. Gomaa, A; Eissa, M; El-Gebaley, A
      The effect of topically applied vasoactive agents and testosterone versus testosterone in the treatment of erectile dysfunction in aged men with low sexual interest

      INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
    68. Kawanishi, Y; Lee, KS; Kimura, K; Koizumi, T; Nakatsuji, H; Kojima, K; Yamamoto, A; Numata, A; Sogou, T
      Screening of ischemic heart disease with cavernous artery blood flow in erectile dysfunctional patients

      INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
    69. Merlin, SL; Brock, GB; Begin, LR; Tim, FFTH; Macramalla, AN; Seyam, RM; Shenouda, G; Dion, SB
      New insights into the role of endothelin-1 in radiation-associated impotence

      INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
    70. Terradas, C; Levalle, O; Nagelberg, A; Mormandi, E
      Sildenafil improves nocturnal penile erections in organic impotence

      INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
    71. Padma-Nathan, H; McMurray, JG; Pullman, WE; Whitaker, JS; Saoud, JB; Ferguson, KM; Rosen, RC
      On-demand IC351 (Cialis (TM)) enhances erectile function in patients with erectile dysfunction

      INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
    72. Uebel, RA; Wium, C; Schmidt, A
      Stability evaluation of a prostaglandin E-1 saline solution packed in insulin syringes

      INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
    73. Utkan, T; Yildirim, MK; Yildirim, S; Sarioglu, Y
      Effects of the specific phosphodiesterase inhibitors on alloxan-induced diabetic rabbit cavernous tissue in vitro

      INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
    74. Jonas, U
      The history of erectile dysfunction management

      INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
    75. von Keitz, A
      The management of erectile dysfunction in the community

      INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
    76. Dundar, SO; Dundar, M; Kocak, I; Dayanir, Y; Ozkan, SB
      Effect of sildenafil on ocular haemodynamics

      EYE
    77. Agelink, MW; Schmitz, T; Rembrink, K; Beckerling, D; Muck-Weymann, M; Mercik, D; Brockmeyer, NH
      Cardiovascular effects of sildenafil citrate (Viagra (R)): A naturalistic cross-over study

      EUROPEAN JOURNAL OF MEDICAL RESEARCH
    78. Cornud, F; Amar, E; Hamida, K; Helenon, O; Moreau, JF
      Ultrasound findings in male hypofertility and impotence

      EUROPEAN RADIOLOGY
    79. Weinmann, W; Bohnert, M; Wiedemann, A; Renz, M; Lehmann, N; Pollak, S
      Post-mortem detection and identification of sildenafil (Viagra) and its metabolites by LC/MS and LC/MS/MS

      INTERNATIONAL JOURNAL OF LEGAL MEDICINE
    80. Turk, S; Karalezli, G; Tonbul, HZ; Yildiz, M; Altintepe, L; Yildiz, A; Yeksan, M
      Erectile dysfunction and the effects of sildenafil treatment in patients on haemodialysis and continuous ambulatory peritoneal dialysis

      NEPHROLOGY DIALYSIS TRANSPLANTATION
    81. Marumo, K; Murai, M
      Aging and erectile dysfunction: The role of aging and concomitant chronic illness

      INTERNATIONAL JOURNAL OF UROLOGY
    82. Kurokawa, K; Suzuki, T; Suzuki, K; Ito, K; Shimizu, N; Fukabori, Y; Yamanaka, H
      A simple and reliable monitoring system to confirm the preservation of thecavernous nerves

      INTERNATIONAL JOURNAL OF UROLOGY
    83. Miyao, N; Adachi, H; Sato, Y; Horita, H; Takahashi, A; Masumori, N; Kitamura, H; Tsukamoto, T
      Recovery of sexual function after nerve-sparing radical prostatectomy or cystectomy

      INTERNATIONAL JOURNAL OF UROLOGY
    84. Marumo, K; Nakashima, J; Murai, M
      Age-related prevalence of erectile dysfunction in Japan: Assessment by theinternational index of erectile function

      INTERNATIONAL JOURNAL OF UROLOGY
    85. Juergensen, PH; Botev, R; Wuerth, D; Finkelstein, SH; Smith, JD; Finkelstein, FO
      Erectile dysfunction in chronic peritoneal dialysis patients: Incidence and treatment with sildenafil

      PERITONEAL DIALYSIS INTERNATIONAL
    86. Kloner, RA; Brown, M; Prisant, LM; Collins, M
      Effect of sildenafil in patients with erectile dysfunction taking antihypertensive therapy

      AMERICAN JOURNAL OF HYPERTENSION
    87. Fishel, B; Chen, J; Alon, M; Zhukovsky, G; Matzkin, H
      Pudendal nerve conduction to evaluate organic erectile dysfunction

      AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION
    88. Bush, HS
      Safe use of sildenafil in patients with coronary artery disease

      CLEVELAND CLINIC JOURNAL OF MEDICINE
    89. Wallner, K
      Improved outcomes with radiation for prostate cancer

      HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA
    90. Bokhour, BG; Clark, JA; Inui, TS; Silliman, RA; Talcott, JA
      Sexuality after treatment for early prostate cancer - Exploring the meanings of "erectile dysfunction"

      JOURNAL OF GENERAL INTERNAL MEDICINE
    91. Vemulapalli, S; Kurowski, S
      Phentolamine mesylate relaxes rabbit corpus cavernosum by a nonadrenergic,noncholinergic mechanism

      FUNDAMENTAL & CLINICAL PHARMACOLOGY
    92. Siu, SC; Lo, SK; Wong, KW; Ip, KM; Wong, YS
      Prevalence of and risk factors for erectile dysfunction in Hong Kong diabetic patients

      DIABETIC MEDICINE
    93. Przyklenk, K; Kloner, RA
      Sildenafil citrate (Viagra) does not exacerbate myocardial ischemia in canine models of coronary artery stenosis

      JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
    94. Becker, AJ; Uckert, S; Stief, CG; Truss, MC; Hartmann, U; Jonas, U
      Systemic and cavernous plasma levels of endothelin (1-21) during differentpenile conditions in healthy males and patients with erectile dysfunction

      WORLD JOURNAL OF UROLOGY
    95. Heaton, JPW
      Key issues from the clinical trials of apomorphine SL

      WORLD JOURNAL OF UROLOGY
    96. Klotz, T; Sachse, R; Heidrich, A; Jockenhovel, F; Rohde, G; Wensing, G; Horstmann, R; Engelmann, R
      Vardenafil increases penile rigidity and tumescence in erectile dysfunction patients: a RigiScan and pharmacokinetic study

      WORLD JOURNAL OF UROLOGY
    97. Nehra, A; Colreavy, F; Khandheria, BK; Chandrasekaran, K
      Sildenafil citrate, a selective phosphodiesterase type 5 inhibitor: urologic and cardiovascular implications

      WORLD JOURNAL OF UROLOGY
    98. Schultheiss, D; Muller, SV; Nager, W; Stief, CG; Schlote, N; Jonas, U; Asvestis, C; Johannes, S; Munte, TF
      Central effects of sildenafil (Viagra) on auditory selective attention andverbal recognition memory in humans: a study with event-related brain potentials

      WORLD JOURNAL OF UROLOGY
    99. Burnett, AL
      Novel pharmacological approaches in the treatment of erectile dysfunction

      WORLD JOURNAL OF UROLOGY
    100. Al-bojuk, NR; El-Abadelah, MM; Sabri, SS; Michel, A; Voelter, W; Mossmer, CM; Al-Abed, Y
      Synthesis and vasorelaxant potency of Monagra. A chiral 5-(2-methyl-2,3-dihydro-7-benzofuryl)pyrazolopyrimidone analog of Viagra((R))

      HETEROCYCLES


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Documento generato il 27/02/20 alle ore 15:39:26