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La ricerca find articoli where soggetti phrase all words 'ENDOPROTEOLYSIS' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 65 riferimenti
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    1. Golde, TE; Younkin, SG
      Presenilins as therapeutic targets for the treatment of Alzheimer's disease

      TRENDS IN MOLECULAR MEDICINE
    2. Sastre, M; Steiner, H; Fuchs, K; Capell, A; Multhaup, G; Condron, MM; Teplow, DB; Haass, C
      Presenilin dependent gamma-secretase processing of beta-amyloid precursor protein at a site corresponding to the S3 cleavage of Notch

      EMBO REPORTS
    3. Chen, FS; Yu, G; Arawaka, S; Nishimura, M; Kawarai, T; Yu, H; Tandon, A; Supala, A; Song, YQ; Rogaeva, E; Milman, P; Sato, C; Yu, C; Janus, C; Lee, J; Song, LX; Zhang, LL; Fraser, PE; St George-Hyslop, PH
      Nicastrin binds to membrane tethered Notch

      NATURE CELL BIOLOGY
    4. Petit, A; Bihel, F; da Costa, CA; Pourquie, O; Checler, F; Kraus, JL
      New protease inhibitors prevent gamma-secretase-mediated production of A beta 40/42 without affecting Notch cleavage

      NATURE CELL BIOLOGY
    5. Armogida, M; Petit, A; Vincent, B; Scarzello, S; da Costa, CA; Checler, F
      Endogenous beta-amyloid production in presenilin-deficient embryonic mousefibroblasts

      NATURE CELL BIOLOGY
    6. Steiner, H; Haass, C
      Nuclear signaling - A common function of presenilin substrates?

      JOURNAL OF MOLECULAR NEUROSCIENCE
    7. Wolfe, MS
      gamma-secretase inhibitors as molecular probes of presenilin function

      JOURNAL OF MOLECULAR NEUROSCIENCE
    8. Mann, DMA; Takeuchi, A; Sato, S; Cairns, NJ; Lantos, PL; Rossor, MN; Haltia, M; Kalimo, H; Iwatsubo, T
      Cases of Alzheimer's disease due to deletion of exon 9 of the presenilin-1gene show an unusual but characteristic beta-amyloid pathology known as 'cotton wool' plaques

      NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
    9. Yamamoto, A; Behl, C
      Human Nck-associated protein1 and its binding protein affect the metabolism of beta-amyloid precursor protein with Swedish mutation

      NEUROSCIENCE LETTERS
    10. Sisodia, SS; Annaert, W; Kim, SH; De Strooper, B
      gamma-secretase: Never more enigmatic

      TRENDS IN NEUROSCIENCES
    11. Baki, L; Marambaud, P; Efthimiopoulos, S; Georgakopoulos, A; Wen, P; Cui, W; Shioi, J; Koo, E; Ozawa, M; Friedrich, VL; Robakis, NK
      Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120association, and regulates stability and function of the cadherin/catenin adhesion complex

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    12. Levitan, D; Lee, J; Song, LX; Manning, R; Wong, G; Parker, E; Zhang, LL
      PS1N-and C-terminal fragments form a complex that functions in APP processing and Notch signaling

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    13. Selkoe, DJ
      Presenilin, Notch, and the genesis and treatment of Alzheimer's disease

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    14. Checler, F
      The multiple paradoxes of presenilins

      JOURNAL OF NEUROCHEMISTRY
    15. Tomita, M; Sugi, K; Ozawa, K; Tsong, TY; Yoshimura, T
      Targeting antigen-specific receptors on B lymphocytes to generate high yields of specific monoclonal antibodies directed against biologically active lower antigenic peptides within presenilin 1

      JOURNAL OF IMMUNOLOGICAL METHODS
    16. Soriano, S; Kang, DE; Fu, MF; Pestell, R; Chevallier, N; Zheng, H; Koo, EH
      Presenilin 1 negatively regulates beta-catenin/T cell factor/lymphoid enhancer factor-1 signaling independently of beta-amyloid precursor protein andNotch processing

      JOURNAL OF CELL BIOLOGY
    17. Yu, CJ; Kim, SH; Ikeuchi, T; Xu, HX; Gasparini, L; Wang, R; Sisodia, SS
      Characterization of a presenilin-mediated amyloid precursor protein carboxyl-terminal fragment gamma - Evidence for distinct mechanisms involved in gamma-secretase processing or the APP and Notch1 transmembrane domains

      JOURNAL OF BIOLOGICAL CHEMISTRY
    18. Tomita, T; Watabiki, T; Takikawa, R; Morohashi, Y; Takasugi, N; Kopan, R; De Strooper, B; Iwatsubo, T
      The first proline of PALP motif at the C terminus of presenilins is obligatory for stabilization, complex formation, and gamma-secretase activities of presenilins

      JOURNAL OF BIOLOGICAL CHEMISTRY
    19. Choi, EK; Zaidi, NF; Miller, JS; Crowley, AC; Merriam, DE; Lilliehook, C; Buxbaum, JD; Wasco, W
      Calsenilin is a substrate for caspase-3 that preferentially interacts withthe familial Alzheimer's disease-associated C-terminal fragment of presenilin 2

      JOURNAL OF BIOLOGICAL CHEMISTRY
    20. Kirschenbaum, F; Hsu, SC; Cordell, B; McCarthy, JV
      Substitution of a glycogen synthase kinase-3 beta phosphorylation site in presenilin 1 separates presenilin function from beta-catenin signaling

      JOURNAL OF BIOLOGICAL CHEMISTRY
    21. Evin, G; Sharples, RA; Weidemann, A; Reinhard, FBM; Carbone, V; Culvenor, JG; Holsinger, RMD; Sernee, MF; Beyreuther, K; Masters, CL
      Aspartyl protease inhibitor pepstatin binds to the presenilins of Alzheimer's disease

      BIOCHEMISTRY
    22. Park, IH; Jung, MW; Mori, H; Mook-Jung, I
      Zinc enhances synthesis of presenilin 1 in mouse primary cortical culture

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    23. Georgakopoulos, A; Marambaud, P; Robakis, NK; Baki, L
      Presenilin-1 is a regulatory component of the cadherin cell adhesion complex: Implications for Alzheimer's disease

      ALZHEIMER'S DISEASE
    24. Song, WH; Yankner, BA
      Presenilins and notch signaling pathway

      ALZHEIMER'S DISEASE
    25. Steiner, H; Haass, C
      A novel protease active site motif conserved in presenilins and polytopic bacterial aspartyl proteases?

      ALZHEIMER'S DISEASE
    26. Gardell, SJ; Li, YM; Xu, M; Lai, MT; Huang, Q; Castro, JL; DiMuzio-Mower, J; Harrison, T; Lellis, C; Nadin, A; Neduvelil, JG; Register, RB; Sardana, MK; Shearman, MS; Shi, XP; Smith, AL; Yin, KC; Shafer, JA
      Photoactivated, active-site-directed gamma-secretase inhibitors covalentlylabel presenilin 1

      ALZHEIMER'S DISEASE
    27. Esler, WP; Kimberly, WT; Ostaszewski, BL; Diehl, TS; Moore, CL; Tsai, JY; Rahmati, T; Xia, WM; Selkoe, DJ; Wolfe, MS
      Transition-state analogue inhibitors of gamma-secretase bind directly to presenilin-1

      NATURE CELL BIOLOGY
    28. Steiner, H; Kostka, M; Romig, H; Basset, G; Pesold, B; Hardy, J; Capell, A; Meyn, L; Grim, ML; Baumeister, R; Fechteler, K; Haass, C
      Glycine 384 is required for presenilin-1 function and is conserved in bacterial polytopic aspartyl proteases

      NATURE CELL BIOLOGY
    29. Christie, G; Hussain, I; Smith, L; Mansfield, F; Bresciani, L; Davis, JB; Gray, CW; Markwell, R; Wadsworth, H; King, R; McLaughlin, M; Cooper, DG; Karran, E; Ward, RV
      Peptidyl boronic acids inhibit the degradation of presenilin-l in presenilin-l transfected cells

      ALZHEIMERS REPORTS
    30. Van Gassen, G; De Jonghe, C; Nishimura, M; Yu, G; Kuhn, S; St George-Hyslop, PS; Van Broeckhoven, C
      Evidence that the beta-catenin nuclear translocation assay allows for measuring presenilin 1 dysfunction

      MOLECULAR MEDICINE
    31. Tanahashi, H; Tabira, T
      Alzheimer's disease-associated presenilin 2 interacts with DRAL, an LIM-domain protein

      HUMAN MOLECULAR GENETICS
    32. Xia, W
      Role of presenilin in gamma-secretase cleavage of amyloid precursor protein

      EXPERIMENTAL GERONTOLOGY
    33. Song, SC; Ohba, M; Saito, Y; Honda, T; Takashima, A; Takahashi, H
      Proteolytic processing and degradation of human presenilin-1 expressed in yeast

      NEUROSCIENCE LETTERS
    34. Morihara, T; Katayama, T; Sato, N; Yoneda, T; Manabe, T; Hitomi, J; Abe, H; Imaizumi, K; Tohyama, M
      Absence of endoproteolysis but no effects on amyloid beta production by alternative splicing forms of presenilin-1, which lack exon 8 and replace D257A

      MOLECULAR BRAIN RESEARCH
    35. Honda, T; Nihonmatsu, N; Yasutake, K; Ohtake, A; Sato, K; Tanaka, S; Murayama, O; Murayama, M; Takashima, A
      Familial Alzheimer's disease-associated mutations block translocation of full-length presenilin 1 to the nuclear envelope

      NEUROSCIENCE RESEARCH
    36. De Strooper, B
      Alzheimer's disease - Closing in on gamma-secretase

      NATURE
    37. Li, YM; Xu, M; Lai, MT; Huang, Q; Castro, JL; DiMuzio-Mower, J; Harrison, T; Lellis, C; Nadin, JL; Neduvelil, JG; Register, RB; Sardana, MK; Shearman, MS; Smith, AL; Shi, XP; Yin, KC; Shafer, JA; Gardell, SJ
      Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1

      NATURE
    38. Lin, XL; Koelsch, C; Wu, SL; Downs, D; Dashti, A; Tang, J
      Human aspartic protease memapsin 2 cleaves the beta-secretase site of beta-amyloid precursor protein

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    39. Xia, WM; Ray, WJ; Ostaszewski, BL; Rahmati, T; Kimberly, WT; Wolfe, MS; Zhang, JM; Goate, AM; Selkoe, DJ
      Presenilin complexes with the C-terminal fragments of amyloid precursor protein at the sites of amyloid beta-protein generation

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    40. Li, YM; Lai, MT; Xu, M; Huang, Q; DiMuzio-Mower, J; Sardana, MK; Shi, XP; Yin, KC; Shafer, JA; Gardell, SJ
      Presenilin 1 is linked with gamma-secretase activity in the detergent solubilized state

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    41. Guo, YQ; Zhang, SX; Sokol, N; Cooley, L; Boulianne, GL
      Physical and genetic interaction of filamin with presenilin in Drosophila

      JOURNAL OF CELL SCIENCE
    42. Kimberly, WT; Xia, WM; Rahmati, T; Wolfe, MS; Selkoe, DJ
      The transmembrane aspartates in presenilin 1 and 2 are obligatory for gamma-secretase activity and amyloid beta-protein generation

      JOURNAL OF BIOLOGICAL CHEMISTRY
    43. Bennett, BD; Denis, P; Haniu, M; Teplow, DB; Kahn, S; Louis, JC; Citron, M; Vassar, R
      A furin-like convertase mediates propeptide cleavage of BACE, the Alzheimer's beta-secretase

      JOURNAL OF BIOLOGICAL CHEMISTRY
    44. Ermolieff, J; Loy, JA; Koelsch, G; Tang, J
      Proteolytic activation of recombinant pro-memapsin 2 (pro-beta-secretase) studied with new fluorogenic substrates

      BIOCHEMISTRY
    45. Lewis, PA; Perez-Tur, J; Golde, TE; Hardy, J
      The presenilin 1 C92S mutation increases A beta 42 production

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    46. Verdile, G; Fraser, PE; Hyslop, PS; Kwok, JBJ; Schofield, PR; Fisher, C; Helmerhorst, E; Martins, RN
      Decreased secretion of amyloid precursor protein in Chinese hamster ovary cells overexpressing presenilin 1

      ALZHEIMERS REPORTS
    47. Prihar, G; de Chavez, FG; Baker, M; Crook, R; McGowan, E; Grover, A; Hardy, J; Hutton, M
      A novel candidate presenilin-1 interacting protein containing tetratricopeptide repeats

      NEUROREPORT
    48. Tanahashi, H; Tabira, T
      Isolation of human delta-catenin and its binding specificity with presenilin 1

      NEUROREPORT
    49. Shirotani, K; Takahashi, K; Tabira, T
      Effects of presenilin N-terminal fragments on production of amyloid beta peptide and accumulation of endogenous presenilins

      NEUROSCIENCE LETTERS
    50. Takahashi, H; Mercken, M; Honda, T; Saito, Y; Murayama, M; Song, SC; Takashima, A
      Impaired proteolytic processing of Presenilin-1 in chromosome 14-linked familial Alzheimer's disease patient lymphocytes

      NEUROSCIENCE LETTERS
    51. Murayama, O; Murayama, M; Honda, T; Sun, XY; Nihonmatsu, N; Takashima, A
      Twenty-nine missense mutations linked with familial Alzheimer's disease alter the processing of presenilin 1

      PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
    52. Tomita, T; Takikawa, R; Koyama, A; Morohashi, Y; Takasugi, N; Saido, TC; Maruyama, K; Iwatsubo, T
      C terminus of presenilin is required for overproduction of amyloidogenic Abeta 42 through stabilization and endoproteolysis of presenilin

      JOURNAL OF NEUROSCIENCE
    53. Ray, WJ; Yao, M; Nowotny, P; Mumm, J; Zhang, WJ; Wu, JY; Kopan, R; Goate, AM
      Evidence for a physical interaction between presenilin and Notch

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    54. Thinakaran, G
      The role of presenilins in Alzheimer's disease

      JOURNAL OF CLINICAL INVESTIGATION
    55. Steiner, H; Romig, H; Grim, MG; Philipp, U; Pesold, B; Citron, M; Baumeister, R; Haass, C
      The biological and pathological function of the presenilin-1 Delta exon 9 mutation is independent of its defect to undergo proteolytic processing

      JOURNAL OF BIOLOGICAL CHEMISTRY
    56. Tomidokoro, Y; Ishiguro, K; Igeta, Y; Matsubara, E; Kanai, M; Shizuka, M; Kawarabayashi, T; Harigaya, Y; Kawakatsu, S; Ii, K; Ikeda, M; George-Hyslop, PHS; Hirai, S; Okamoto, K; Shoji, M
      Carboxyl-terminal fragments of presenilin-1 are closely related to cytoskeletal abnormalities in Alzheimer's brains

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    57. Miake, H; Tsuchiya, K; Nakamura, A; Ikeda, K; Levesque, L; Fraser, PE; St-George Hyslop, PH; Mizusawa, H; Uchihara, T
      Glial expression of presenilin epitopes in human brain with cerebral infarction and in astrocytoma

      ACTA NEUROPATHOLOGICA
    58. Rohrig, S; Brockhaus, M; Steiner, H; Capell, A; Grunberg, J; Walter, J; Leimer, U; Loetscher, H; Wittenburg, N; Jacobsen, H; Baumeister, R; Haass, C
      Role of presenilin processing and caspases for amyloid beta-peptide generation and NOTCH signaling

      ALZHEIMER'S DISEASE AND RELATED DISORDERS
    59. CITRON M; ECKMAN CB; DIEHL TS; CORCORAN C; OSTASZEWSKI BL; XIA WM; LEVESQUE G; HYSLOP PS; YOUNKIN SG; SELKOE DJ
      ADDITIVE EFFECTS OF PS1 AND APP MUTATIONS ON SECRETION OF THE 42-RESIDUE AMYLOID BETA-PROTEIN

      Neurobiology of disease
    60. PERONE MJ; MURRAY CA; BROWN OA; GIBSON S; WHITE A; LINTON EA; PERKINS AV; LOWENSTEIN PR; CASTRO MG
      PROCORTICOTROPHIN-RELEASING HORMONE - ENDOPROTEOLYTIC PROCESSING AND DIFFERENTIAL RELEASE OF ITS DERIVED PEPTIDES WITHIN ATT20 CELLS

      Molecular and cellular endocrinology
    61. Tesco, G; Kim, TW; Diehlmann, A; Beyreuther, K; Tanzi, RE
      Abrogation of the presenilin 1 beta-catenin interaction and preservation of the heterodimeric presenilin 1 complex following caspase activation

      JOURNAL OF BIOLOGICAL CHEMISTRY
    62. REHFELD JF; HANSEN CP; JOHNSEN AH
      POST-POLY(GLU) CLEAVAGE AND DEGRADATION MODIFIED BY O-SULFATED TYROSINE - A NOVEL POSTTRANSLATIONAL PROCESSING MECHANISM

      EMBO journal
    63. HUPESODMANN K; MCGREGOR GP; BRIDENBAUGH R; RUDIGER G; BURKHARD G; THOLE H; ZIMMERMANN B; VOIGT K
      CHARACTERIZATION OF THE PROCESSING BY HUMAN NEUTRAL ENDOPEPTIDASE-24.11 OF GLP-1(7-36) AMIDE AND COMPARISON OF THE SUBSTRATE-SPECIFICITY OFTHE ENZYME FOR OTHER GLUCAGON-LIKE PEPTIDES

      Regulatory peptides
    64. BLANKE SE; JOHNSEN AH; REHFELD JF
      N-TERMINAL FRAGMENTS OF INTESTINAL CHOLECYSTOKININ - EVIDENCE FOR RELEASE OF CCK-8 BY CLEAVAGE ON THE CARBOXYL SIDE OF ARG(74) OF PROCCK

      Regulatory peptides
    65. MA YT; RANDO RR
      ENDOPROTEOLYSIS OF NON-CAAX-CONTAINING ISOPRENYLATED PEPTIDES

      FEBS letters


ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/02/20 alle ore 11:45:06