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1. Iida, A; Sekine, A; Saito, S; Kitamura, Y; Kitamoto, T; Osawa, S; Mishima, C; Nakamura, Y
   Catalog of 320 single nucleotide polymorphisms (SNPs) in 20 quinone oxidoreductase and sulfotransferase genes
   JOURNAL OF HUMAN GENETICS
   
   A. Iida et al., "Catalog of 320 single nucleotide polymorphisms (SNPs) in 20 quinone oxidoreductase and sulfotransferase genes", J HUM GENET, 46(4), 2001, pp. 225-240
2. Kong, ANT; Yu, R; Hebbar, V; Chen, C; Owuor, E; Hu, R; Ee, R; Mandlekar, S
   Signal transduction events elicited by cancer prevention compounds
   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
   
   A.N.T. Kong et al., "Signal transduction events elicited by cancer prevention compounds", MUT RES-F M, 480, 2001, pp. 231-241
3. Thornton, AS; Oda, Y; Stuart, G; Glickman, BW; de Boer, JG
   Mutagenicity of TCDD in big Blue (R) transgenic rats
   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
   
   A.S. Thornton et al., "Mutagenicity of TCDD in big Blue (R) transgenic rats", MUT RES-F M, 478(1-2), 2001, pp. 45-50
4. Mersch-Sundermann, V; Schneider, H; Freywald, C; Jenter, C; Parzefall, W; Knasmuller, S
   Musk ketone enhances benzo(a)pyrene induced mutagenicity in human derived Hep G2 cells
   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
   
   V. Mersch-Sundermann et al., "Musk ketone enhances benzo(a)pyrene induced mutagenicity in human derived Hep G2 cells", MUT RES-GTE, 495(1-2), 2001, pp. 89-96
5. Guyonnet, D; Belloir, C; Suschetet, M; Siess, MH; Le Bon, AM
   Antimutagenic activity of organosulfur compounds from Allium is associatedwith phase II enzyme induction
   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
   
   D. Guyonnet et al., "Antimutagenic activity of organosulfur compounds from Allium is associatedwith phase II enzyme induction", MUT RES-GTE, 495(1-2), 2001, pp. 135-145
6. Bofinger, DP; Feng, L; Chi, LH; Love, J; Stephen, FD; Sutter, TR; Osteen, KG; Costich, TG; Batt, RE; Koury, ST; Olson, JR
   Effect of TCDD exposure on CYP1A1 and CYP1B1 expression in explant cultures of human endometrium
   TOXICOLOGICAL SCIENCES
   
   D.P. Bofinger et al., "Effect of TCDD exposure on CYP1A1 and CYP1B1 expression in explant cultures of human endometrium", TOXICOL SCI, 62(2), 2001, pp. 299-314
7. Nebbia, C
   Biotransformation enzymes as determinants of xenobiotic toxicity in domestic animals
   VETERINARY JOURNAL
   
   C. Nebbia, "Biotransformation enzymes as determinants of xenobiotic toxicity in domestic animals", VET J, 161(3), 2001, pp. 238-252
8. Leblond, F; Guevin, C; Demers, C; Pellerin, I; Gascon-Barre, M; Pichette, V
   Downregulation of hepatic cytochrome P450 in chronic renal failure
   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
   
   F. Leblond et al., "Downregulation of hepatic cytochrome P450 in chronic renal failure", J AM S NEPH, 12(2), 2001, pp. 326-332
9. Okamoto, T; Momose, S; Hino, O
   Suppression of cytochrome P450 1A1 and 4A1 gene expression in renal carcinomas of TSC2 gene mutant (Eker) rats
   INTERNATIONAL JOURNAL OF ONCOLOGY
   
   T. Okamoto et al., "Suppression of cytochrome P450 1A1 and 4A1 gene expression in renal carcinomas of TSC2 gene mutant (Eker) rats", INT J ONCOL, 18(1), 2001, pp. 147-149
10. Loizou, GD; Cocker, J
    The effects of alcohol and diallyl sulphide on CYP2E1 activity in humans: a phenotyping study using chlorzoxazone
    HUMAN & EXPERIMENTAL TOXICOLOGY
    
    G.D. Loizou e J. Cocker, "The effects of alcohol and diallyl sulphide on CYP2E1 activity in humans: a phenotyping study using chlorzoxazone", HUM EXP TOX, 20(7), 2001, pp. 321-327
11. Wan, YJY; Poland, RE; Han, G; Konishi, T; Zheng, YP; Berman, N; Lin, KM
    Analysis of the CYP2D6 gene polymorphism and enzyme activity in African-Americans in Southern California
    PHARMACOGENETICS
    
    Y.J.Y. Wan et al., "Analysis of the CYP2D6 gene polymorphism and enzyme activity in African-Americans in Southern California", PHARMACOGEN, 11(6), 2001, pp. 489-499
12. Griese, EU; Ilett, KF; Kitteringham, NR; Eichelbaum, M; Powell, H; Spargo, RM; LeSouef, PN; Musk, AW; Minchin, RF
    Allele and genotype frequencies of polymorphic cytochromes P4502D6, 2C19 and 2E1 in Aborigines from Western Australia
    PHARMACOGENETICS
    
    E.U. Griese et al., "Allele and genotype frequencies of polymorphic cytochromes P4502D6, 2C19 and 2E1 in Aborigines from Western Australia", PHARMACOGEN, 11(1), 2001, pp. 69-76
13. Saraswathy, SD; Devi, CSS
    Modulating effect of Liv.100, an ayurvedic formulation on antituberculosisdrug-induced alterations in rat liver microsomes
    PHYTOTHERAPY RESEARCH
    
    S.D. Saraswathy e C.S.S. Devi, "Modulating effect of Liv.100, an ayurvedic formulation on antituberculosisdrug-induced alterations in rat liver microsomes", PHYTOTHER R, 15(6), 2001, pp. 501-505
14. Davis, MP; Homsi, J
    The importance of cytochrome P450 monooxygenase CYP2D6 in palliative medicine
    SUPPORTIVE CARE IN CANCER
    
    M.P. Davis e J. Homsi, "The importance of cytochrome P450 monooxygenase CYP2D6 in palliative medicine", SUPP CARE C, 9(6), 2001, pp. 442-451
15. Kuhn, UD; Rost, M; Muller, D
    Para-nitropbenol glucuronidation and sulfation in rat and human liver slices
    EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY
    
    U.D. Kuhn et al., "Para-nitropbenol glucuronidation and sulfation in rat and human liver slices", EXP TOX PAT, 53(1), 2001, pp. 81-87
16. Gelardi, A; Morini, F; Dusatti, F; Penco, S; Ferro, M
    Induction by xenobiotics of phase I and phase II enzyme activities in the human keratinocyte cell line NCTC 2544
    TOXICOLOGY IN VITRO
    
    A. Gelardi et al., "Induction by xenobiotics of phase I and phase II enzyme activities in the human keratinocyte cell line NCTC 2544", TOX VITRO, 15(6), 2001, pp. 701-711
17. Beaune, P
    Diet, genetics and cancer
    GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE
    
    P. Beaune, "Diet, genetics and cancer", GASTRO CL B, 25(4), 2001, pp. B20-B25
18. Lin, JH; Lu, AYH
    Interindividual variability in inhibition and induction of cytochrome P450enzymes
    ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY
    
    J.H. Lin e A.Y.H. Lu, "Interindividual variability in inhibition and induction of cytochrome P450enzymes", ANN R PHARM, 41, 2001, pp. 535-567
19. Xie, HG; Kim, RB; Wood, AJJ; Stein, CM
    Molecular basis of ethnic differences in drug disposition and response
    ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY
    
    H.G. Xie et al., "Molecular basis of ethnic differences in drug disposition and response", ANN R PHARM, 41, 2001, pp. 815-850
20. Bournique, B; Lambert, N; Boukaiba, R; Martinet, M
    In vitro metabolism and drug interaction potential of a new highly potent anti-cytomegalovirus molecule, CMV423 (2-chloro 3-pyridine 3-yl 5,6,7,8-tetrahydroindolizine 1-carboxamide)
    BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    
    B. Bournique et al., "In vitro metabolism and drug interaction potential of a new highly potent anti-cytomegalovirus molecule, CMV423 (2-chloro 3-pyridine 3-yl 5,6,7,8-tetrahydroindolizine 1-carboxamide)", BR J CL PH, 52(1), 2001, pp. 53-63
21. Dasgupta, T; Banerjee, S; Yadav, PK; Rao, AR
    Chemomodulation of carcinogen metabolising enzymes, antioxidant profiles and skin and forestomach papillomagenesis by Spirulina platensis
    MOLECULAR AND CELLULAR BIOCHEMISTRY
    
    T. Dasgupta et al., "Chemomodulation of carcinogen metabolising enzymes, antioxidant profiles and skin and forestomach papillomagenesis by Spirulina platensis", MOL C BIOCH, 226(1-2), 2001, pp. 27-38
22. Sheweita, SA; Abu El-Maati, MR; El-Shahat, FG; Bazeed, MA
    Changes in the expression of cytochrome P450 2E1 and the activity of carcinogen-metabolizing enzymes in Schistosoma haematobium-infected human bladder tissues
    TOXICOLOGY
    
    S.A. Sheweita et al., "Changes in the expression of cytochrome P450 2E1 and the activity of carcinogen-metabolizing enzymes in Schistosoma haematobium-infected human bladder tissues", TOXICOLOGY, 162(1), 2001, pp. 43-52
23. Debersac, P; Heydel, JM; Amiot, MJ; Goudonnet, H; Artur, Y; Suschetet, M; Siess, MH
    Induction of cytochrome P450 and/or detoxication enzymes by various extracts of rosemary: description of specific patterns
    FOOD AND CHEMICAL TOXICOLOGY
    
    P. Debersac et al., "Induction of cytochrome P450 and/or detoxication enzymes by various extracts of rosemary: description of specific patterns", FOOD CHEM T, 39(9), 2001, pp. 907-918
24. Bernardini, S; Hirvonen, A; Jarventaus, H; Norppa, H
    Trans-stilbene oxide-induced sister chromatid exchange in cultured human lymphocytes: influence of GSTM1 and GSTT1 genotypes
    MUTAGENESIS
    
    S. Bernardini et al., "Trans-stilbene oxide-induced sister chromatid exchange in cultured human lymphocytes: influence of GSTM1 and GSTT1 genotypes", MUTAGENESIS, 16(3), 2001, pp. 277-281
25. De Smet, K; Cavin, C; Vercruysse, A; Rogiers, V
    Collagen type I gel cultures of adult rat hepatocytes as a screening induction model for cytochrome P450-dependent enzymes
    ATLA-ALTERNATIVES TO LABORATORY ANIMALS
    
    K. De Smet et al., "Collagen type I gel cultures of adult rat hepatocytes as a screening induction model for cytochrome P450-dependent enzymes", ATLA-ALT L, 29(2), 2001, pp. 179-192
26. Giorgi, M; Salvatori, AP; Soldani, G; Giusiani, M; Longo, V; Gervasi, PG; Mengozzi, G
    Pharmacokinetics and microsomal oxidation of praziquantel and its effects on the P450 system in three-month-old lambs infested by Fasciola hepatica
    JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS
    
    M. Giorgi et al., "Pharmacokinetics and microsomal oxidation of praziquantel and its effects on the P450 system in three-month-old lambs infested by Fasciola hepatica", J VET PHARM, 24(4), 2001, pp. 251-259
27. Myers, MJ; Farrell, DE; Howard, KD; Kawalek, JC
    Identification of multiple constitutive and inducible hepatic cytochrome P450 enzymes in market weight swine
    DRUG METABOLISM AND DISPOSITION
    
    M.J. Myers et al., "Identification of multiple constitutive and inducible hepatic cytochrome P450 enzymes in market weight swine", DRUG META D, 29(6), 2001, pp. 908-915
28. Fraile, LJ; Bregante, MA; Garcia, MA; Solans, C
    Development of diltiazem deacetylase and demethylase activities during ontogeny in rabbit
    XENOBIOTICA
    
    L.J. Fraile et al., "Development of diltiazem deacetylase and demethylase activities during ontogeny in rabbit", XENOBIOTICA, 31(7), 2001, pp. 409-422
29. Dohr, O; Paine, MJI; Friedberg, T; Roberts, GCK; Wolf, CR
    Engineering of a functional human NADH-dependent cytochrome P450 system
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    
    O. Dohr et al., "Engineering of a functional human NADH-dependent cytochrome P450 system", P NAS US, 98(1), 2001, pp. 81-86
30. Vang, O; Mortensen, J; Andersen, O
    Biochemical effects of dietary intake of different broccoli samples. II. Multivariate analysis of contributions of specific glucosinolates in modulating cytochrome P-450 and antioxidant defense enzyme activities
    METABOLISM-CLINICAL AND EXPERIMENTAL
    
    O. Vang et al., "Biochemical effects of dietary intake of different broccoli samples. II. Multivariate analysis of contributions of specific glucosinolates in modulating cytochrome P-450 and antioxidant defense enzyme activities", METABOLISM, 50(10), 2001, pp. 1130-1135
31. Lee, SE; Campbell, BC; Molyneux, RJ; Hasegawa, S; Lee, HS
    Inhibitory effects of naturally occurring compounds on aflatoxin B-1 biotransformation
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
    
    S.E. Lee et al., "Inhibitory effects of naturally occurring compounds on aflatoxin B-1 biotransformation", J AGR FOOD, 49(11), 2001, pp. 5171-5177
32. Sreerama, L; Sladek, NE
    Three different stable human breast adenocarcinoma sublines that overexpress ALDH3A1 and certain other enzymes, apparently as a consequence of constitutively upregulated gene transcription mediated by transactivated EpREs (electrophile responsive elements) present in the 5 '-upstream regions of these genes
    CHEMICO-BIOLOGICAL INTERACTIONS
    
    L. Sreerama e N.E. Sladek, "Three different stable human breast adenocarcinoma sublines that overexpress ALDH3A1 and certain other enzymes, apparently as a consequence of constitutively upregulated gene transcription mediated by transactivated EpREs (electrophile responsive elements) present in the 5 '-upstream regions of these genes", CHEM-BIO IN, 130(1-3), 2001, pp. 247-260
33. Dupuy, J; Larrieu, G; Braun, J; Alvinerie, M; Galtier, P
    Differential effects of phenobarbital on the constitutive and inducible expression of P4502B and 3A subfamilies in sheep tissues
    CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
    
    J. Dupuy et al., "Differential effects of phenobarbital on the constitutive and inducible expression of P4502B and 3A subfamilies in sheep tissues", CAN J PHYSL, 79(10), 2001, pp. 848-853
34. Janmohamed, A; Dolphin, CT; Phillips, IR; Shephard, EA
    Quantification and cellular localization of expression in human skin of genes encoding flavin-containing monooxygenases and cytochromes P450
    BIOCHEMICAL PHARMACOLOGY
    
    A. Janmohamed et al., "Quantification and cellular localization of expression in human skin of genes encoding flavin-containing monooxygenases and cytochromes P450", BIOCH PHARM, 62(6), 2001, pp. 777-786
35. Ezzat, AR; el-Din, SHS; Ebeid, FA
    Effect of praziquantel treatment on the activities of some liver microsomal enzymes in mice infected with Schistosoma mansoni
    ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH
    
    A.R. Ezzat et al., "Effect of praziquantel treatment on the activities of some liver microsomal enzymes in mice infected with Schistosoma mansoni", ARZNEI-FOR, 51(4), 2001, pp. 325-331
36. Jude, AR; Little, JM; Czernik, PJ; Tephly, TR; Grant, DF; Radominska-Pandya, A
    Glucuronidation of linoleic acid diols by human microsomal and recombinantUDP-glucuronosyltransferases: Identification of UGT2B7 as the major isoform involved
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
    
    A.R. Jude et al., "Glucuronidation of linoleic acid diols by human microsomal and recombinantUDP-glucuronosyltransferases: Identification of UGT2B7 as the major isoform involved", ARCH BIOCH, 389(2), 2001, pp. 176-186
37. Geisler, SA; Olshan, AF
    GSTM1, GSTT1, and the risk of squamous cell carcinoma of the head and neck: A Mini-HuGE review
    AMERICAN JOURNAL OF EPIDEMIOLOGY
    
    S.A. Geisler e A.F. Olshan, "GSTM1, GSTT1, and the risk of squamous cell carcinoma of the head and neck: A Mini-HuGE review", AM J EPIDEM, 154(2), 2001, pp. 95-105
38. Sanchez-Campos, S; Gonzalez, P; Ferreras, C; Garcia-Iglesias, MJ; Gonzalez-Gallego, J; Tunon, MJ
    Morphologic and biochemical changes caused by experimentally induced dicroceliosis in hamsters (Mesocricetus auratus)
    COMPARATIVE MEDICINE
    
    S. Sanchez-Campos et al., "Morphologic and biochemical changes caused by experimentally induced dicroceliosis in hamsters (Mesocricetus auratus)", COMPAR MED, 50(2), 2000, pp. 147-152
39. Meisel, C; Roots, I; Cascorbi, I; Brinkmann, U; Brockmoller, J
    How to manage individualized drug therapy: Application of pharmacogenetic knowledge of drug metabolism and transport
    CLINICAL CHEMISTRY AND LABORATORY MEDICINE
    
    C. Meisel et al., "How to manage individualized drug therapy: Application of pharmacogenetic knowledge of drug metabolism and transport", CLIN CH L M, 38(9), 2000, pp. 869-876
40. Guyonnet, D; Belloir, C; Suschetet, M; Siess, MH; Le Bon, AM
    Liver subcellular fractions from rats treated by organosulfur compounds from Allium modulate mutagen activation
    MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
    
    D. Guyonnet et al., "Liver subcellular fractions from rats treated by organosulfur compounds from Allium modulate mutagen activation", MUT RES-GTE, 466(1), 2000, pp. 17-26
41. McWilliams, JE; Evans, AJ; Beer, TM; Andersen, PE; Cohen, JI; Everts, EC; Henner, WD
    Genetic polymorphisms in head and neck cancer risk
    HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
    
    J.E. McWilliams et al., "Genetic polymorphisms in head and neck cancer risk", HEAD NECK, 22(6), 2000, pp. 609-617
42. Fisher, MB; VandenBranden, M; Findlay, K; Burchell, B; Thummel, KE; Hall, SD; Wrighton, SA
    Tissue distribution and interindividual variation in human UDP-glucuronosyltransferase activity: relationship between UGT1A1 promoter genotype and variability in a liver bank
    PHARMACOGENETICS
    
    M.B. Fisher et al., "Tissue distribution and interindividual variation in human UDP-glucuronosyltransferase activity: relationship between UGT1A1 promoter genotype and variability in a liver bank", PHARMACOGEN, 10(8), 2000, pp. 727-739
43. Nebert, DW
    Suggestions for the nomenclature of human alleles: relevance to ecogenetics, pharmacogenetics and molecular epidemiology
    PHARMACOGENETICS
    
    D.W. Nebert, "Suggestions for the nomenclature of human alleles: relevance to ecogenetics, pharmacogenetics and molecular epidemiology", PHARMACOGEN, 10(4), 2000, pp. 279-290
44. Duthie, GG; Duthie, SJ; Kyle, JAM
    Plant polyphenols in cancer and heart disease: implications as nutritionalantioxidants
    NUTRITION RESEARCH REVIEWS
    
    G.G. Duthie et al., "Plant polyphenols in cancer and heart disease: implications as nutritionalantioxidants", NUTR RES R, 13(1), 2000, pp. 79-106
45. Mochizuki, H; Takido, J; Oda, H; Yokogoshi, H
    Amplifing effect of dietary taurine on the induction of cytochrome P-450 and on the urinary excretion of ascorbic acid in rats fed on phenobarbital-containing diets
    BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
    
    H. Mochizuki et al., "Amplifing effect of dietary taurine on the induction of cytochrome P-450 and on the urinary excretion of ascorbic acid in rats fed on phenobarbital-containing diets", BIOS BIOT B, 64(2), 2000, pp. 405-407
46. Riedl, AG; Watts, PM; Douek, DC; Edwards, RJ; Boobis, AR; Rose, S; Jenner, P
    Expression and distribution of CYP2C enzymes in rat basal ganglia
    SYNAPSE
    
    A.G. Riedl et al., "Expression and distribution of CYP2C enzymes in rat basal ganglia", SYNAPSE, 38(4), 2000, pp. 392-402
47. Beaune, PH; Loriot, MA
    Molecular basis of individual susceptibility to xenobiotics
    M S-MEDECINE SCIENCES
    
    P.H. Beaune e M.A. Loriot, "Molecular basis of individual susceptibility to xenobiotics", M S-MED SCI, 16(10), 2000, pp. 1051-1056
48. Galijatovic, A; Walle, UK; Walle, T
    Induction of UDP-glucuronosyl-transferase by the flavonoids chrysin and quercetin in Caco-2 cells
    PHARMACEUTICAL RESEARCH
    
    A. Galijatovic et al., "Induction of UDP-glucuronosyl-transferase by the flavonoids chrysin and quercetin in Caco-2 cells", PHARM RES, 17(1), 2000, pp. 21-26
49. Koleva, M; Dimova, S
    Effects of nifedipine, verapamil, diltiazem and trifluoperazine on the antinociceptive activity of acetaminophen
    METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY
    
    M. Koleva e S. Dimova, "Effects of nifedipine, verapamil, diltiazem and trifluoperazine on the antinociceptive activity of acetaminophen", METH FIND E, 22(10), 2000, pp. 741-745
50. Suter-Eichenberger, R; Boelsterli, UA; Conscience-Egli, M; Lichtensteiger, W; Schlumpf, M
    CYP 450 enzyme induction by chronic oral musk xylene in adult and developing rats (vol 111, pg 117, 1999)
    TOXICOLOGY LETTERS
    
    R. Suter-Eichenberger et al., "CYP 450 enzyme induction by chronic oral musk xylene in adult and developing rats (vol 111, pg 117, 1999)", TOX LETT, 115(1), 2000, pp. 71
51. Guerre, P; Pineau, T; Costet, P; Burgat, V; Galtier, P
    Effects of AFB1 on CYP 1A1, 1A2 and 3A6 mRNA, and P450 expression in primary culture of rabbit hepatocytes
    TOXICOLOGY LETTERS
    
    P. Guerre et al., "Effects of AFB1 on CYP 1A1, 1A2 and 3A6 mRNA, and P450 expression in primary culture of rabbit hepatocytes", TOX LETT, 111(3), 2000, pp. 243-251
52. Bart, J; Groen, HJM; Hendrikse, NH; van der Graaf, WTA; Vaalburg, W; de Vries, EGE
    The blood-brain barrier and oncology: new insights into function and modulation
    CANCER TREATMENT REVIEWS
    
    J. Bart et al., "The blood-brain barrier and oncology: new insights into function and modulation", CANC TR REV, 26(6), 2000, pp. 449-462
53. Rieder, CRM; Parsons, RB; Fitch, NJS; Williams, AC; Ramsden, DB
    Human brain cytochrome P4501B1: immunohistochemical localization in human temporal lobe and induction by dimethylbenz(a)anthracene in astrocytoma cell line (MOG-G-CCM)
    NEUROSCIENCE LETTERS
    
    C.R.M. Rieder et al., "Human brain cytochrome P4501B1: immunohistochemical localization in human temporal lobe and induction by dimethylbenz(a)anthracene in astrocytoma cell line (MOG-G-CCM)", NEUROSCI L, 278(3), 2000, pp. 177-180
54. Sarkar, A; Saha, BK; Basak, R; Mukhopadhyay, I; Karmakar, R; Chatterjee, M
    Anticlastogenic potential of 1 alpha,25-dihydroxyvitamin D-3 in murine lymphoma
    CANCER LETTERS
    
    A. Sarkar et al., "Anticlastogenic potential of 1 alpha,25-dihydroxyvitamin D-3 in murine lymphoma", CANCER LETT, 150(1), 2000, pp. 1-13
55. Singh, RP; Padmavathi, B; Rao, AR
    Modulatory influence of Adhatoda vesica (Justicia adhatoda) leaf extract on the enzymes of xenobiotic metabolism, antioxidant status and lipid peroxidation in mice
    MOLECULAR AND CELLULAR BIOCHEMISTRY
    
    R.P. Singh et al., "Modulatory influence of Adhatoda vesica (Justicia adhatoda) leaf extract on the enzymes of xenobiotic metabolism, antioxidant status and lipid peroxidation in mice", MOL C BIOCH, 213(1-2), 2000, pp. 99-109
56. Hashemi, E; Till, C; Ioannides, C
    Stability of cytochrome P450 proteins in cultured precision-cut rat liver slices
    TOXICOLOGY
    
    E. Hashemi et al., "Stability of cytochrome P450 proteins in cultured precision-cut rat liver slices", TOXICOLOGY, 149(2-3), 2000, pp. 51-61
57. Singh, A; Singh, SP; Bamezai, R
    Direct and translactational effect of arecoline alkaloid on the clocimum oil-modulated hepatic drug metabolizing enzymes in mice
    FOOD AND CHEMICAL TOXICOLOGY
    
    A. Singh et al., "Direct and translactational effect of arecoline alkaloid on the clocimum oil-modulated hepatic drug metabolizing enzymes in mice", FOOD CHEM T, 38(7), 2000, pp. 627-635
58. Groten, JP; Butler, W; Feron, VJ; Kozianowski, G; Renwick, AC; Walker, R
    An analysis of the possibility for health implications of joint actions and interactions between food additives
    REGULATORY TOXICOLOGY AND PHARMACOLOGY
    
    J.P. Groten et al., "An analysis of the possibility for health implications of joint actions and interactions between food additives", REGUL TOX P, 31(1), 2000, pp. 77-91
59. Guengerich, FP
    Pharmacogenomics of cytochrome P450 and other enzymes involved in biotransformation of xenobiotics
    DRUG DEVELOPMENT RESEARCH
    
    F.P. Guengerich, "Pharmacogenomics of cytochrome P450 and other enzymes involved in biotransformation of xenobiotics", DRUG DEV R, 49(1), 2000, pp. 4-16
60. Mukhopadhyay, S; Singh, M; Chatterjee, M
    Vitamin D-3 as a modulator of cellular antioxidant defence in murine lymphoma
    NUTRITION RESEARCH
    
    S. Mukhopadhyay et al., "Vitamin D-3 as a modulator of cellular antioxidant defence in murine lymphoma", NUTR RES, 20(1), 2000, pp. 91-102
61. Kong, ANT; Yu, R; Chen, C; Mandlekar, S; Primiano, T
    Signal transduction events elicited by natural products: Role of MAPK and caspase pathways in homeostatic response and induction of apoptosis
    ARCHIVES OF PHARMACAL RESEARCH
    
    A.N.T. Kong et al., "Signal transduction events elicited by natural products: Role of MAPK and caspase pathways in homeostatic response and induction of apoptosis", ARCH PH RES, 23(1), 2000, pp. 1-16
62. Mankowski, DC; Lawton, MP; Ekins, S
    Characterization of transgenic mouse strains using six human hepatic cytochrome P450 probe substrates
    XENOBIOTICA
    
    D.C. Mankowski et al., "Characterization of transgenic mouse strains using six human hepatic cytochrome P450 probe substrates", XENOBIOTICA, 30(8), 2000, pp. 745-754
63. Ledirac, N; Delescluse, C; Lesca, P; Piechocki, MP; Hines, RN; de Sousa, G; Pralavorio, M; Rahmani, R
    Diflubenzuron, a benzoyl-urea insecticide, is a potent inhibitor of TCDD-induced CYP1A1 expression in HepG2 cells
    TOXICOLOGY AND APPLIED PHARMACOLOGY
    
    N. Ledirac et al., "Diflubenzuron, a benzoyl-urea insecticide, is a potent inhibitor of TCDD-induced CYP1A1 expression in HepG2 cells", TOX APPL PH, 164(3), 2000, pp. 273-279
64. Nebert, DW; Dieter, MZ
    The evolution of drug metabolism
    PHARMACOLOGY
    
    D.W. Nebert e M.Z. Dieter, "The evolution of drug metabolism", PHARMACOL, 61(3), 2000, pp. 124-135
65. Ouzzine, M; Antonio, L; Burchell, B; Netter, P; Fournel-Gigleux, S; Magdalou, J
    Importance of histidine residues for the function of the human liver UDP-glucuronosyltransferase UGT1A6: Evidence for the catalytic role of histidine370
    MOLECULAR PHARMACOLOGY
    
    M. Ouzzine et al., "Importance of histidine residues for the function of the human liver UDP-glucuronosyltransferase UGT1A6: Evidence for the catalytic role of histidine370", MOLEC PHARM, 58(6), 2000, pp. 1609-1615
66. Slattery, ML; Kampman, E; Samowitz, W; Caan, BJ; Potter, JD
    Interplay between dietary inducers of GST and the GSTM-1 genotype in coloncancer
    INTERNATIONAL JOURNAL OF CANCER
    
    M.L. Slattery et al., "Interplay between dietary inducers of GST and the GSTM-1 genotype in coloncancer", INT J CANC, 87(5), 2000, pp. 728-733
67. Nebert, DW
    Extreme discordant phenotype methodology: an intuitive approach to clinical pharmacogenetics
    EUROPEAN JOURNAL OF PHARMACOLOGY
    
    D.W. Nebert, "Extreme discordant phenotype methodology: an intuitive approach to clinical pharmacogenetics", EUR J PHARM, 410(2-3), 2000, pp. 107-120
68. Delker, DA; Papanikolaou, A; Suhr, YJ; Rosenberg, DW
    Diallyl sulfide enhances azoxymethane-induced preneoplasia in Fischer 344 rat colon
    CHEMICO-BIOLOGICAL INTERACTIONS
    
    D.A. Delker et al., "Diallyl sulfide enhances azoxymethane-induced preneoplasia in Fischer 344 rat colon", CHEM-BIO IN, 124(3), 2000, pp. 149-160
69. Hodges, VM; Molloy, GY; Wickramasinghe, SN
    Demonstration of mRNA for five species of cytochrome P450 in human bone marrow, bone marrow-derived macrophages and human haemopoietic cell lines
    BRITISH JOURNAL OF HAEMATOLOGY
    
    V.M. Hodges et al., "Demonstration of mRNA for five species of cytochrome P450 in human bone marrow, bone marrow-derived macrophages and human haemopoietic cell lines", BR J HAEM, 108(1), 2000, pp. 151-156
70. Solans, C; Bregante, MA; Aramayona, JJ; Fraile, LJ; Garcia, MA
    Pharmacokinetics of verapamil in New Zealand white rabbits during ontogeny
    BIOLOGY OF THE NEONATE
    
    C. Solans et al., "Pharmacokinetics of verapamil in New Zealand white rabbits during ontogeny", BIOL NEONAT, 78(4), 2000, pp. 321-326
71. Iba, MM; Fung, J; Cooper, KR; Thomas, PE; Wagner, G; Park, Y
    Effect of gestational and lactational 2,3,7,8 tetrachlorodibenzo-p-dioxin exposure on the level and catalytic activities of hepatic microsomal CYP1A in prepubertal and adult rats
    BIOCHEMICAL PHARMACOLOGY
    
    M.M. Iba et al., "Effect of gestational and lactational 2,3,7,8 tetrachlorodibenzo-p-dioxin exposure on the level and catalytic activities of hepatic microsomal CYP1A in prepubertal and adult rats", BIOCH PHARM, 59(9), 2000, pp. 1147-1154
72. Sinclair, JF; Szakacs, JG; Wood, SG; Kostrubsky, VE; Jeffery, EH; Wrighton, SA; Bement, WJ; Wright, D; Sinclair, PR
    Acetaminophen hepatotoxicity precipitated by short-term treatment of rats with ethanol and isopentanol - Protection by triacetyloleandomycin
    BIOCHEMICAL PHARMACOLOGY
    
    J.F. Sinclair et al., "Acetaminophen hepatotoxicity precipitated by short-term treatment of rats with ethanol and isopentanol - Protection by triacetyloleandomycin", BIOCH PHARM, 59(4), 2000, pp. 445-454
73. Nebert, DW; Roe, AL; Dieter, MZ; Solis, WA; Yang, Y; Dalton, TP
    Role of the aromatic hydrocarbon receptor and [Ah] gene battery in the oxidative stress response, cell cycle control, and apoptosis
    BIOCHEMICAL PHARMACOLOGY
    
    D.W. Nebert et al., "Role of the aromatic hydrocarbon receptor and [Ah] gene battery in the oxidative stress response, cell cycle control, and apoptosis", BIOCH PHARM, 59(1), 2000, pp. 65-85
74. Ebeid, FA; el-Din, SHS; Ezzat, AR
    Effect of Schistosoma mansoni infection and treatment on drug metabolizingenzymes
    ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH
    
    F.A. Ebeid et al., "Effect of Schistosoma mansoni infection and treatment on drug metabolizingenzymes", ARZNEI-FOR, 50(9), 2000, pp. 867-874
75. Jude, AR; Little, JM; Freeman, JP; Evans, JE; Radominska-Pandya, A; Grant, DF
    Linoleic acid diols are novel substrates for human UDP-glucuronosyltransferases
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
    
    A.R. Jude et al., "Linoleic acid diols are novel substrates for human UDP-glucuronosyltransferases", ARCH BIOCH, 380(2), 2000, pp. 294-302
76. Lakritz, J; Winder, BS; Noorouz-Zadeh, J; Huang, TL; Buckpitt, AR; Hammock, BD; Plopper, CG
    Hepatic and pulmonary enzyme activities in horses
    AMERICAN JOURNAL OF VETERINARY RESEARCH
    
    J. Lakritz et al., "Hepatic and pulmonary enzyme activities in horses", AM J VET RE, 61(2), 2000, pp. 152-157
77. Brockton, N; Little, J; Sharp, L; Cotton, SC
    N-Acetyltransferase polymorphisms and colorectal cancer: A HuGE review
    AMERICAN JOURNAL OF EPIDEMIOLOGY
    
    N. Brockton et al., "N-Acetyltransferase polymorphisms and colorectal cancer: A HuGE review", AM J EPIDEM, 151(9), 2000, pp. 846-861
78. Nebbia, C; Ceppa, L; Dacasto, M; Carletti, M
    Triphenyltin acetate-mediated in vitro inactivation of rat liver cytochrome P-450
    JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A
    
    C. Nebbia et al., "Triphenyltin acetate-mediated in vitro inactivation of rat liver cytochrome P-450", J TOX E H A, 56(6), 1999, pp. 433-447
79. Sladek, NE
    Aldehyde dehydrogenase-mediated cellular relative insensitivity to the oxazaphosphorines
    CURRENT PHARMACEUTICAL DESIGN
    
    N.E. Sladek, "Aldehyde dehydrogenase-mediated cellular relative insensitivity to the oxazaphosphorines", CUR PHARM D, 5(8), 1999, pp. 607-625
80. Baranova, H; Canis, M; Ivaschenko, T; Albuisson, E; Bothorishvilli, R; Baranov, V; Malet, P; Bruhat, MA
    Possible involvement of arylamine N-acetyltransferase 2, glutathione S-transferases M1 and T1 genes in the development of endometriosis
    MOLECULAR HUMAN REPRODUCTION
    
    H. Baranova et al., "Possible involvement of arylamine N-acetyltransferase 2, glutathione S-transferases M1 and T1 genes in the development of endometriosis", MOL HUM REP, 5(7), 1999, pp. 636-641
81. Baranov, VS; Ivashchenko, TE; Shved, NY; Yarmolinskaya, MI; Sel'kov, SA; Gorbushin, SM; Savitskii, GA; Malet, P; Kanis, M; Bruhat, M; Baranova, E
    Genetic factors determining predisposition to endometriosis and response to its treatment
    RUSSIAN JOURNAL OF GENETICS
    
    V.S. Baranov et al., "Genetic factors determining predisposition to endometriosis and response to its treatment", RUSS J GEN, 35(2), 1999, pp. 189-193
82. Bishayee, A; Roy, S; Chatterjee, M
    Characterization of selective induction and alteration of xenobiotic biotransforming enzymes by vanadium during diethylnitrosamine-induced chemical rat liver carcinogenesis
    ONCOLOGY RESEARCH
    
    A. Bishayee et al., "Characterization of selective induction and alteration of xenobiotic biotransforming enzymes by vanadium during diethylnitrosamine-induced chemical rat liver carcinogenesis", ONCOL RES, 11(1), 1999, pp. 41-53
83. Rocha, L; Garcia, C; de Mendonca, A; Gil, JP; Bishop, DT; Lechner, MC
    N-acetyltransferase (NAT2) genotype and susceptibility to sporadic Alzheimer's disease
    PHARMACOGENETICS
    
    L. Rocha et al., "N-acetyltransferase (NAT2) genotype and susceptibility to sporadic Alzheimer's disease", PHARMACOGEN, 9(1), 1999, pp. 9-15
84. Reen, RK; Melo, GEBA; Moraes-Santos, T
    Malnutrition sequela on the drug metabolizing enzymes in male Holtzman rats
    JOURNAL OF NUTRITIONAL BIOCHEMISTRY
    
    R.K. Reen et al., "Malnutrition sequela on the drug metabolizing enzymes in male Holtzman rats", J NUTR BIOC, 10(10), 1999, pp. 615-618
85. Sanchez-Campos, S; Tunon, MJ; Gonzalez, P; Gonzalez-Gallego, J
    Oxidative stress and changes in liver antioxidant enzymes induced by experimental dicroceliosis in hamsters
    PARASITOLOGY RESEARCH
    
    S. Sanchez-Campos et al., "Oxidative stress and changes in liver antioxidant enzymes induced by experimental dicroceliosis in hamsters", PARASIT RES, 85(6), 1999, pp. 468-474
86. King, LC; Adams, L; Allison, J; Kohan, MJ; Nelson, G; Desai, D; Amin, S; Ross, JA
    A quantitative comparison of dibenzo[a,I]pyrene-DNA adduct formation by recombinant human cytochrome P450 microsomes
    MOLECULAR CARCINOGENESIS
    
    L.C. King et al., "A quantitative comparison of dibenzo[a,I]pyrene-DNA adduct formation by recombinant human cytochrome P450 microsomes", MOL CARCINO, 26(2), 1999, pp. 74-82
87. Le Couteur, DG; McLean, AJ; Taylor, MC; Woodham, BL; Board, PG
    Pesticides and Parkinson's disease
    BIOMEDICINE & PHARMACOTHERAPY
    
    D.G. Le Couteur et al., "Pesticides and Parkinson's disease", BIOMED PHAR, 53(3), 1999, pp. 122-130
88. Kong, ANT; Mandlekar, S; Yu, R; Lei, W; Fasanmande, A
    Pharmacodynamics and toxicodynamics of drug action: Signaling in cell survival and cell death
    PHARMACEUTICAL RESEARCH
    
    A.N.T. Kong et al., "Pharmacodynamics and toxicodynamics of drug action: Signaling in cell survival and cell death", PHARM RES, 16(6), 1999, pp. 790-798
89. Suter-Eichenberger, R; Boelsterli, UA; Conscience-Egli, M; Lichtensteiger, W; Schlumpf, M
    CYP 450 enzyme induction by chronic oral musk xylene in adult and developing rats
    TOXICOLOGY LETTERS
    
    R. Suter-Eichenberger et al., "CYP 450 enzyme induction by chronic oral musk xylene in adult and developing rats", TOX LETT, 111(1-2), 1999, pp. 117-132
90. Guerre, P; Larrieu, G; Burgat, V; Galtier, P
    Cytochrome P450 decreases are correlated to increased microsomal oxidativedamage in rabbit liver and primary cultures of rabbit hepatocytes exposed to AFB1
    TOXICOLOGY LETTERS
    
    P. Guerre et al., "Cytochrome P450 decreases are correlated to increased microsomal oxidativedamage in rabbit liver and primary cultures of rabbit hepatocytes exposed to AFB1", TOX LETT, 104(1-2), 1999, pp. 117-125
91. Gradinaru, D; Suleman, FG; Leclerc, S; Heydel, JM; Grillasca, JP; Magdalou, J; Minn, A
    UDP-glucuronosyltransferase in the rat olfactory bulb: Identification of the UGT1A6 isoform and age-related changes in 1-naphthol glucuronidation
    NEUROCHEMICAL RESEARCH
    
    D. Gradinaru et al., "UDP-glucuronosyltransferase in the rat olfactory bulb: Identification of the UGT1A6 isoform and age-related changes in 1-naphthol glucuronidation", NEUROCHEM R, 24(8), 1999, pp. 995-1000
92. Radominska-Pandya, A; Czernik, PJ; Little, JM; Battaglia, E; Mackenzie, PI
    Structural and functional studies of UDP-glucuronosyltransferases
    DRUG METABOLISM REVIEWS
    
    A. Radominska-Pandya et al., "Structural and functional studies of UDP-glucuronosyltransferases", DRUG METAB, 31(4), 1999, pp. 817-899
93. Bock, KW; Gschaidmeier, H; Heel, H; Lehmkoster, T; Munzel, PA; Bock-Hennig, BS
    Functions and transcriptional regulation of PAH-inducible human UDP-glucuronosyltransferases
    DRUG METABOLISM REVIEWS
    
    K.W. Bock et al., "Functions and transcriptional regulation of PAH-inducible human UDP-glucuronosyltransferases", DRUG METAB, 31(2), 1999, pp. 411-422
94. Manson, MM; Benford, DJ
    Factors influencing the carcinogenicity of food chemicals
    TOXICOLOGY
    
    M.M. Manson e D.J. Benford, "Factors influencing the carcinogenicity of food chemicals", TOXICOLOGY, 134(2-3), 1999, pp. 93-108
95. Newberne, P; Smith, RL; Doull, J; Goodman, JI; Munro, IC; Portoghese, PS; Wagner, BM; Weil, CS; Woods, LA; Adams, TB; Lucas, CD; Ford, RA
    The FEMA GRAS assessment of trans-anethole used as a flavouring substance
    FOOD AND CHEMICAL TOXICOLOGY
    
    P. Newberne et al., "The FEMA GRAS assessment of trans-anethole used as a flavouring substance", FOOD CHEM T, 37(7), 1999, pp. 789-811
96. Singh, A; Singh, SP; Bamezai, R
    Modulatory potential of clocimum oil mouse skin papillomagenesis and the xenobiotic detoxication system
    FOOD AND CHEMICAL TOXICOLOGY
    
    A. Singh et al., "Modulatory potential of clocimum oil mouse skin papillomagenesis and the xenobiotic detoxication system", FOOD CHEM T, 37(6), 1999, pp. 663-670
97. Jinno, H; Hatakeyama, N; Hanioka, N; Yoda, R; Nishimura, T; Ando, M
    Cytotoxic and porphyrinogenic effects of diphenyl ethers in cultured rat hepatocytes: Chlornitrofen (CNP), CNP-amino, chlomethoxyfen and bifenox
    FOOD AND CHEMICAL TOXICOLOGY
    
    H. Jinno et al., "Cytotoxic and porphyrinogenic effects of diphenyl ethers in cultured rat hepatocytes: Chlornitrofen (CNP), CNP-amino, chlomethoxyfen and bifenox", FOOD CHEM T, 37(1), 1999, pp. 69-74
98. Patterson, LH; McKeown, SR; Robson, T; Gallagher, R; Raleigh, SM; Orr, S
    Antitumour prodrug development using cytochrome P450 (CYP) mediated activation
    ANTI-CANCER DRUG DESIGN
    
    L.H. Patterson et al., "Antitumour prodrug development using cytochrome P450 (CYP) mediated activation", ANTI-CAN DR, 14(6), 1999, pp. 473-486
99. Kaledin, VI; Gulyaeva, LF; Vavilin, VA; Makarova, SI; Moroskova, TS; Richter, VA
    Activity of drug-metabolyzing enzymes in the liver of SWR and C3HA mice sensitive to hepatocarcinogenic action of ortho-aminoazotoluene versus resistant AKR and CC57BR strains
    EXPERIMENTAL ONCOLOGY
    
    V.I. Kaledin et al., "Activity of drug-metabolyzing enzymes in the liver of SWR and C3HA mice sensitive to hepatocarcinogenic action of ortho-aminoazotoluene versus resistant AKR and CC57BR strains", EXP ONCOL, 21(1), 1999, pp. 18-23
100. Munday, R; Munday, CM
     Low doses of diallyl disulfide, a compound derived from garlic, increase tissue activities of quinone reductase and glutathione transferase in the gastrointestinal tract of the rat
     NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
     
     R. Munday e C.M. Munday, "Low doses of diallyl disulfide, a compound derived from garlic, increase tissue activities of quinone reductase and glutathione transferase in the gastrointestinal tract of the rat", NUTR CANCER, 34(1), 1999, pp. 42-48