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    1. Katchamart, S; Williams, DE
      Indole-3-carbinol modulation of hepatic monooxygenases CYP1A1, CYP1A2 and FMO1 in guinea pig, mouse and rabbit

      COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
    2. Evans, WE; Johnson, JA
      Pharmacogenomics: The inherited basis for interindividual differences in drug response

      ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS
    3. Haverkamp, W; Eckardt, L; Monnig, G; Schulze-Bahr, E; Wedekind, H; Kirchhof, P; Haverkamp, F; Breithardt, G
      Clinical aspects of ventricular arrhythmias associated with QT prolongation

      EUROPEAN HEART JOURNAL SUPPLEMENTS
    4. Bauman, JL
      The role of pharmacokinetics, drug interactions and pharmacogenetics in the acquired long QT syndrome

      EUROPEAN HEART JOURNAL SUPPLEMENTS
    5. Tong, V; Abbott, FS; Mbofana, S; Walker, MJA
      In vitro investigation of the hepatic extraction of RSD1070, a novel antiarrhythmic compound

      JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES
    6. Pillans, PI
      Increasing relevance of pharmacogenetics of drug metabolism in clinical practice

      INTERNAL MEDICINE JOURNAL
    7. Anzenbacher, P; Anzenbacherova, E
      Cytochromes P450 and metabolism of xenobiotics

      CELLULAR AND MOLECULAR LIFE SCIENCES
    8. Tarui, N; Ikeura, Y; Natsugari, H; Nakahama, K
      Microbial synthesis of three metabolites of a tachykinin receptor antagonist, TAK-637

      JOURNAL OF BIOSCIENCE AND BIOENGINEERING
    9. Guengerich, FP
      Forging the links between metabolism and carcinogenesis

      MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
    10. Rahden-Staron, I; Czeczot, H; Szumilo, M
      Induction of rat liver cytochrome P450 isoenzymes CYP 1A and CYP2B by different fungicides, nitrofurans, and quercetin

      MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
    11. Liu, XG; Li, RC
      Effects of repeated rifabutin administration on the pharmacokinetics of intravenous and oral ciprofloxacin in mice

      JOURNAL OF CHEMOTHERAPY
    12. Dialyna, IA; Arvanitis, DA; Spandidos, DA
      Genetic polymorphisms and transcriptional pattern analysis of CYP1A1, AhR,GSTM1, GSTP1 and GSTT1 genes in breast cancer

      INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
    13. Gerhold, D; Lu, MQ; Xu, J; Austin, C; Caskey, CT; Rushmore, T
      Monitoring expression of genes involved in drug metabolism and toxicology using DNA microarrays

      PHYSIOLOGICAL GENOMICS
    14. Delaporte, E; Slaughter, DE; Egan, MA; Gatto, GJ; Santos, A; Shelley, J; Price, E; Howells, L; Dean, DC; Rodrigues, AD
      The potential for CYP2D6 inhibition screening using a novel scintillation proximity assay-based approach

      JOURNAL OF BIOMOLECULAR SCREENING
    15. Kariv, I; Fereshteh, MP; Oldenburg, KR
      Development of a miniaturized 384-well high throughput screen for the detection of substrates of cytochrome P-450 2D6 and 3A4 metabolism

      JOURNAL OF BIOMOLECULAR SCREENING
    16. Lhoest, G; Hertsens, R; Verbeeck, RK; Maton, N; Wallemacq, P; Dehoux, JP; Latinne, D
      In vitro immunosuppressive activity of tacrolimus dihydrodiol precursors obtained by chemical oxidation and identification of a new metabolite of SDZ-RAD by electrospray and electrospray-linked scan mass spectrometry

      JOURNAL OF MASS SPECTROMETRY
    17. McFee, RB; Caraccio, TR; Mofenson, HC
      Selected tricyclic antidepressant ingestions involving children 6 years old or less

      ACADEMIC EMERGENCY MEDICINE
    18. Kuehl, P; Zhang, J; Lin, Y; Lamba, J; Assem, M; Schuetz, J; Watkins, PB; Daly, A; Wrighton, SA; Hall, SD; Maurel, P; Relling, M; Brimer, C; Yasuda, K; Venkataramanan, R; Strom, S; Thummel, K; Boguski, MS; Schuetz, E
      Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

      NATURE GENETICS
    19. Oscarson, M
      Nicotine metabolism by the polymorphic cytochrome P450 2A6 (CYP2A6) enzyme: Implications for interindividual differences in smoking behaviour target article on nicotine-addiction

      PSYCOLOQUY
    20. Hocht, C; Opezzo, JAW; Gorzalczany, SB; Priano, RM; Bramuglia, GF; Taira, CA
      Pharmacokinetic and pharmacodynamic alterations of methyldopa in rats withaortic coarctation. A study using microdialysis

      PHARMACOLOGICAL RESEARCH
    21. Opezzo, JAW; Hocht, C; Taira, CA; Bramuglia, GF
      Pharmacokinetic study of methyldopa in aorta-coarctated rats using a microdialysis technique

      PHARMACOLOGICAL RESEARCH
    22. Zanger, UM; Fischer, J; Raimundo, S; Stuven, T; Evert, BO; Schwab, M; Eichelbaum, M
      Comprehensive analysis of the genetic factors determining expression and function of hepatic CYP2D6

      PHARMACOGENETICS
    23. Caraco, Y; Muszkat, M; Wood, AJJ
      Phenytoin metabolic ratio: a putative marker of CYP2C9 activity in vivo

      PHARMACOGENETICS
    24. Ramamoorthy, Y; Tyndale, RF; Sellers, EM
      Cytochrome P450 2D6.1 and cytochrome P450 2D6.10 differ in catalytic activity for multiple substrates

      PHARMACOGENETICS
    25. Eiselt, R; Domanski, TL; Zibat, A; Mueller, R; Presecan-Siedel, E; Hustert, E; Zanger, UM; Brockmoller, J; Klenk, HP; Meyer, UA; Khan, KK; He, YA; Halpert, JR; Wojnowski, L
      Identification and functional characterization of eight CYP3A4 protein variants

      PHARMACOGENETICS
    26. Vallee, M; Albert, C; Beaudry, G; Hum, DW; Belanger, A
      Isolation and characterization of the monkey UDP-glucuronosyltransferase cDNA clone monUGT1A01 active on bilirubin and estrogens

      JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
    27. Dohmer, J
      Modern drug development by molecular and cell biological methods

      ALTEX-ALTERNATIVEN ZU TIEREXPERIMENTEN
    28. Wiela-Hojenska, A; Gorczynska, E; Orzechowska-Juzwenko, K; Golebiowski, W; Hurkacz, M; Boguslawska-Jaworska, J
      Metabolic functions of the liver during chemotherapy in children with acute lymphoblastic leukemia

      INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS
    29. Lelouet, H; Bechtel, YC; Paintaud, G; Brientini, MP; Miguet, JP; Bechtel, PR
      Caffeine metabolism in a group, of 67 patients with primary biliary cirrhosis

      INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS
    30. Davis, MP; Homsi, J
      The importance of cytochrome P450 monooxygenase CYP2D6 in palliative medicine

      SUPPORTIVE CARE IN CANCER
    31. Kuhn, UD; Rost, M; Muller, D
      Para-nitropbenol glucuronidation and sulfation in rat and human liver slices

      EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY
    32. Lemire, J; Capparelli, EV; Benador, N; Grimm, P; Macdonald, D; Reznik, V
      Neoral pharmacokinetics in Latino and Caucasian pediatric renal transplantrecipients

      PEDIATRIC NEPHROLOGY
    33. Katoh, M; Nakajima, M; Yamazaki, H; Yokoi, T
      Inhibitory effects of CYP3A4 substrates and their metabolites on P-glycoprotein-mediated transport

      EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
    34. Kosel, M; Amey, M; Aubert, AC; Baumann, P
      In vitro metabolism of citalopram by monoamine oxidase B in human blood

      EUROPEAN NEUROPSYCHOPHARMACOLOGY
    35. Sekine, I; Saijo, N
      Polymorphisms of metabolizing enzymes and transporter proteins involved inthe clearance of anticancer agents

      ANNALS OF ONCOLOGY
    36. Matsunaga, N; Hattori, K; Iizasa, H; Kizu, J; Takanaka, A; Nakashima, E
      Application of the PKCYP-test in cases of altered CYP1A2 for multiple CYP systems in rat models of disease

      BIOLOGICAL & PHARMACEUTICAL BULLETIN
    37. Matsunaga, N; Nishijima, T; Hattori, K; Iizasa, H; Yamamoto, K; Kizu, J; Takanaka, A; Morikawa, A; Nakashima, E
      Application of the PKCYP-test to predict the amount of in vivo CYP2C11 using tolbutamide as a probe

      BIOLOGICAL & PHARMACEUTICAL BULLETIN
    38. Skalova, L; Szotakova, B; Lamka, J; Kral, R; Vankova, I; Baliharova, V; Wsol, V
      Biotransformation of flobufen enantiomers in ruminant hepatocytes and subcellular fractions

      CHIRALITY
    39. Baker, TK; Carfagna, MA; Gao, H; Dow, ER; Li, QQ; Searfoss, GH; Ryan, TP
      Temporal gene expression analysis of monolayer cultured rat hepatocytes

      CHEMICAL RESEARCH IN TOXICOLOGY
    40. Turesky, RJ; Parisod, V; Huynh-Ba, T; Langouet, S; Guengerich, FP
      Regioselective differences in C-8- and N-oxidation of 2-amino-3,8-dimethylimidazo [4,5-f]quinoxaline by human and rat liver microsomes and cytochromes p450 1A2

      CHEMICAL RESEARCH IN TOXICOLOGY
    41. Xue, LL; Wang, HF; Wang, QM; Szklarz, GD; Domanski, TL; Halpert, JR; Correia, MA
      Influence of P450 3A4 SRS-2 residues on cooperativity and/or regioselectivity of aflatoxin B-1 oxidation

      CHEMICAL RESEARCH IN TOXICOLOGY
    42. Cai, HL; Guengerich, FP
      Reaction of trichloroethylene and trichloroethylene oxide with cytochrome P450 enzymes: Inactivation and sites of modification

      CHEMICAL RESEARCH IN TOXICOLOGY
    43. Coecke, S; Bogni, A; Langezaal, I; Worth, A; Hartung, T; Monshouwer, M
      The use of genetically engineered cells for assessing CYP2D6-related polymorphic effects

      TOXICOLOGY IN VITRO
    44. Yoshitomi, S; Ikemoto, K; Takahashi, J; Miki, H; Namba, M; Asahi, S
      Establishment of the transformants expressing human cytochrome P450 subtypes in HepG2, and their applications on drug metabolism and toxicology

      TOXICOLOGY IN VITRO
    45. Hylek, EM
      Oral anticoagulants - Pharmacologic issues for use in the elderly

      CLINICS IN GERIATRIC MEDICINE
    46. Battle, T; Stacey, G
      Cell culture models for hepatotoxicology

      CELL BIOLOGY AND TOXICOLOGY
    47. Sidelmann, UG; Bjornsdottir, I; Shockcor, JP; Hansen, SH; Lindon, JC; Nicholson, JK
      Directly coupled HPLC-NMR and HPLC-MS approaches for the rapid characterisation of drug metabolites in urine: application to the human metabolism of naproxen

      JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
    48. Dixit, RK; Chawla, AB; Kumar, N; Garg, SK
      Effect of omeprazole on the pharmacokinetics of sustained-release carbamazepine in healthy male volunteers

      METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY
    49. Ubeaud, G; Schiller, CD; Hurbin, F; Jaeck, D; Coassolo, P
      Comparison of the stability of some major cytochrome P450 and conjugation reactions in rat, dog and human hepatocyte monolayers

      EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS
    50. Wasan, KM
      Formulation and physiological and biopharmaceutical issues in the development of oral lipid-based drug delivery systems

      DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
    51. Murray, GI; Melvin, WT; Greenlee, WF; Burke, MD
      Regulation, function, and tissue-specific expression of cytochrome P450CYP1B1

      ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY
    52. Park, BK; Kitteringham, NR; O'Neill, PM
      Metabolism of fluorine-containing drugs

      ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY
    53. Mannering, GJ
      A life in science: Biochemist-nutritionist-forensic toxicologst-pharmacologist

      DRUG METABOLISM REVIEWS
    54. Yule, SM; Price, L; Cole, M; Pearson, ADJ; Boddy, AV
      Cyclophosphamide metabolism in children following a 1-h and a 24-h infusion

      CANCER CHEMOTHERAPY AND PHARMACOLOGY
    55. Sreerama, L; Sladek, NE
      Primary breast tumor levels of suspected molecular determinants of cellular sensitivity to cyclophosphamide, ifosfamide, and certain other anticanceragents as predictors of paired metastatic tumor levels of these determinants - Rational individualization of cancer chemotherapeutic regimens

      CANCER CHEMOTHERAPY AND PHARMACOLOGY
    56. Zuegge, J; Schneider, G; Coassolo, P; Lave, T
      Prediction of hepatic metabolic clearance - Comparison and assessment of prediction models

      CLINICAL PHARMACOKINETICS
    57. Treluyer, JM; Rey, E; Sonnier, M; Pons, G; Cresteil, T
      Evidence of impaired cisapride metabolism in neonates

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    58. Calafatti, SA; Ortiz, RAM; Deguer, M; Martinez, M; Pedrazzoli, J
      Effect of acid secretion blockade by omeprazole on the relative bioavailability of orally administered furazolidone in healthy volunteers

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    59. Shaw, MA
      New insights into drug metabolism and toxicology - Report of a symposium on drug metabolism and toxicity held at the British Pharmacological Society Meeting in Cardiff, UK, in July 2000

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    60. Urban, P; Jobert, AS; Laine, R; Pompon, D
      Cytochrome P450 (CYP) mutants and substrate-specificity alterations: segment-directed mutagenesis applied to human CYP1A1

      BIOCHEMICAL SOCIETY TRANSACTIONS
    61. McGinnity, DF; Riley, RJ
      Predicting drug pharmacokinetics in humans from in vitro metabolism studies

      BIOCHEMICAL SOCIETY TRANSACTIONS
    62. Kirk, CJ; Harris, RM; Wood, DM; Waring, RH; Hughes, PJ
      Do dietary phytoestrogens influence susceptibility to hormone-dependent cancer by disrupting the metabolism of endogenous oestrogens?

      BIOCHEMICAL SOCIETY TRANSACTIONS
    63. Pichler, WJ
      Predictive drug allergy testing: an alternative viewpoint

      TOXICOLOGY
    64. Dorne, JLCM; Walton, K; Renwick, AG
      Uncertainty factors for chemical risk assessment: human variability in thepharmacokinetics of CYP1A2 probe substrates

      FOOD AND CHEMICAL TOXICOLOGY
    65. Gremse, DA; Sindel, LJ; Hoff, CJ; Wells, DJ; Boerth, RC
      Assessment of hepatic function in cystic fibrosis by lidocaine metabolism

      JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
    66. Le Couteur, DG; Cogger, VC; Markus, AMA; Harvey, PJ; Yin, ZL; Ansselin, AD; McLean, AJ
      Pseudocapillarization and associated energy limitation in the aged rat liver

      HEPATOLOGY
    67. Horai, Y; Kimura, M; Furuie, H; Matsuguma, K; Irie, S; Koga, Y; Nagahama, T; Murakami, M; Matsui, T; Yao, T; Urae, A; Ishizaki, T
      Pharmacodynamic effects and kinetic disposition of rabeprazole in relationto CYP2C19 genotypes

      ALIMENTARY PHARMACOLOGY & THERAPEUTICS
    68. Ding, S; Yao, D; Deeni, YY; Burchell, B; Wolf, CR; Friedberg, T
      Human NADPH-P450 oxidoreductase modulates the level of cytochrome P450CYP2D6 holoprotein via haem oxygenase-dependent and -independent pathways

      BIOCHEMICAL JOURNAL
    69. Hayhurst, GP; Harlow, J; Chowdry, J; Gross, E; Hilton, E; Lennard, MS; Tucker, GT; Ellis, SW
      Influence of phenylalanine-481 substitutions on the catalytic activity of cytochrome P450 2D6

      BIOCHEMICAL JOURNAL
    70. Shu, Y; Cheng, ZN; Liu, ZQ; Wang, LS; Zhu, B; Huang, SL; Ou-Yang, DS; Zhou, HH
      Interindividual variations in levels and activities of cytochrome P-450 inliver microsomes of Chinese subjects

      ACTA PHARMACOLOGICA SINICA
    71. Kumar, GN; Surapaneni, S
      Role of drug metabolism in drug discovery and development

      MEDICINAL RESEARCH REVIEWS
    72. Thompson, TN
      Optimization of metabolic stability as a goal of modern drug design

      MEDICINAL RESEARCH REVIEWS
    73. Lam, LCW; Garcia-Barcelo, MM; Ungvari, GS; Tang, WK; Lam, VKL; Kwong, SL; Lau, BST; Kwong, PPK; Waye, MMY; Chiu, HFK
      Cytochrome P450 2D6 genotyping and association with tardive dyskinesia in Chinese schizophrenic patients

      PHARMACOPSYCHIATRY
    74. Ponsoda, X; Pareja, E; Gomez-Lechon, MJ; Fabra, R; Carrasco, E; Trullenque, R; Castell, JV
      Drug biotransformation by human hepatocytes. In vitro/in vivo metabolism by cells from the same donor

      JOURNAL OF HEPATOLOGY
    75. Ozdemir, V; Basile, VS; Masellis, M; Kennedy, JL
      Pharmacogenetic assessment of antipsychotic-induced movement disorders: contribution of the dopamine D3 receptor and cytochrome P450 1A2 genes

      JOURNAL OF BIOCHEMICAL AND BIOPHYSICAL METHODS
    76. Jorquera, F; Almar, M; Linares, A; Olcoz, JL; Rodrigo, L; Gonzalez-Gallego, J
      Antipyrine clearance and metabolite formation in primary biliary cirrhosis

      DIGESTIVE DISEASES AND SCIENCES
    77. Schulze, TG; Schumacher, J; Muller, DJ; Krauss, H; Alfter, D; Maroldt, A; Ahle, G; Maroldt, AO; Fernandez, ANY; Weber, T; Held, T; Propping, P; Maier, W; Nothen, MM; Rietschel, M
      Lack of association between a functional polymorphism of the cytochrome P450 1A2 (CYP1A2) gene and Tardive dyskinesia in schizophrenia

      AMERICAN JOURNAL OF MEDICAL GENETICS
    78. Mifsud, J; Millership, JS; Collier, PS; Morrow, R; Hamilton, JTG; McRoberts, WC
      Quantification of urinary excretion of ethosuximide enantiomers and their major metabolites in the rat

      BIOPHARMACEUTICS & DRUG DISPOSITION
    79. Khalil, WF; Saitoh, T; Shimoda, M; Kokue, E
      In vitro cytochrome P450-mediated hepatic activities for five substrates in specific pathogen free chickens

      JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS
    80. Dupuy, J; Larrieu, G; Sutra, JF; Eeckhoutte, C; Alvinerie, M
      Influence of verapamil on the efflux and metabolism of C-14 moxidectin in cultured rat hepatocytes

      JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS
    81. Gruchalla, RS
      Drug metabolism, danger signals, and drug-induced hypersensitivity

      JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
    82. Ariano, RE; Duke, PC; Sitar, DS
      Population pharmacokinetics of fentanyl in healthy volunteers

      JOURNAL OF CLINICAL PHARMACOLOGY
    83. Yates, CR; Vysokanov, A; Mukherjee, A; Ludden, TM; Tolley, E; Meduri, GU; Dalton, JT
      Time-variant increase in methylprednisolone clearance in patients with acute respiratory distress syndrome: A population pharmacokinetic study

      JOURNAL OF CLINICAL PHARMACOLOGY
    84. Venkatakrishnan, K; Schmider, J; Harmatz, JS; Ehrenberg, BL; von Moltke, LL; Graf, JA; Mertzanis, P; Corbett, KE; Rodriguez, MC; Shader, RI; Greenblatt, DJ
      Relative contribution of CYP3A to amitriptyline clearance in humans: In vitro and in vivo studies

      JOURNAL OF CLINICAL PHARMACOLOGY
    85. Allen, SW; Mueller, L; Williams, SN; Quattrochi, LC; Raucy, J
      The use of a high-volume screening procedure to assess the effects of dietary flavonoids on human CYP1A1 expression

      DRUG METABOLISM AND DISPOSITION
    86. Ekins, S; De Groot, MJ; Jones, JP
      Pharmacophore and three-dimensional quantitative structure activity relationship methods for modeling cytochrome P450 active sites

      DRUG METABOLISM AND DISPOSITION
    87. Hewitt, NJ; Buhring, KU; Dasenbrock, J; Haunschild, J; Ladstetter, B; Utesch, D
      Studies comparing in vivo : in vitro metabolism of three pharmaceutical compounds in rat, dog, monkey, and human using cryopreserved hepatocytes, microsomes, and collagen gel immobilized hepatocyte cultures

      DRUG METABOLISM AND DISPOSITION
    88. Yasar, U; Tybring, G; Hidestrand, M; Oscarson, M; Ingelman-Sundberg, M; Dahl, ML; Eliasson, E
      Role of CYP2C9 polymorphism in losartan oxidation

      DRUG METABOLISM AND DISPOSITION
    89. Akira, K; Negishi, E; Imachi, M; Hashimoto, T
      Direct nuclear magnetic resonance spectroscopic analysis of C-13-labeled antipyrine metabolites in human urine

      DRUG METABOLISM AND DISPOSITION
    90. Andersson, TB; Sjoberg, H; Hoffmann, KJ; Boobis, AR; Watts, P; Edwards, RJ; Lake, BG; Price, RJ; Renwick, AB; Gomez-Lechon, MJ; Castell, JV; Ingelman-Sundberg, M; Hidestrand, M; Goldfarb, PS; Lewis, DFV; Corcos, L; Guillouzo, A; Taavitsainen, P; Pelkonen, O
      An assessment of human liver-derived in vitro systems to predict the in vivo metabolism and clearance of almokalant

      DRUG METABOLISM AND DISPOSITION
    91. Nomeir, AA; Ruegg, C; Shoemaker, M; Favreau, LV; Palamanda, JR; Silber, P; Lin, CC
      Inhibition of CYP3A4 in a rapid microtiter plate assay using recombinant enzyme and in human liver microsomes using conventional substrates

      DRUG METABOLISM AND DISPOSITION
    92. Lin, Y; Lu, P; Tang, C; Mei, Q; Sandig, G; Rodrigues, AD; Rushmore, TH; Shou, M
      Substrate inhibition kinetics for cytochrome P450-catalyzed reactions

      DRUG METABOLISM AND DISPOSITION
    93. Chun, YJ; Ryu, SY; Jeong, TC; Kim, MY
      Mechanism-based inhibition of human cytochrome p450 1A1 by rhapontigenin

      DRUG METABOLISM AND DISPOSITION
    94. Yamazaki, H; Komatsu, T; Takemoto, K; Saeki, M; Minami, Y; Kawaguchi, Y; Shimada, N; Nakajima, M; Yokoi, T
      Decreases in phenytoin hydroxylation activities catalyzed by liver microsomal cytochrome P450 enzymes in phenytoin-treated rats

      DRUG METABOLISM AND DISPOSITION
    95. Morgan, ET
      Regulation of cytochrome P450 by inflammatory mediators: Why and how?

      DRUG METABOLISM AND DISPOSITION
    96. Li, C; Chauret, N; Trimble, LA; Nicoll-Griffith, DA; Silva, JM; Macdonald, D; Perrier, H; Yergey, JA; Parton, T; Alexander, RP; Warrellow, GJ
      Investigation of the in vitro metabolism profile of a phosphodiesterase-IVinhibitor, CDP-840: Leading to structural optimization

      DRUG METABOLISM AND DISPOSITION
    97. Gerbal-Chaloin, S; Pascussi, JM; Pichard-Garcia, L; Daujat, M; Waechter, F; Fabre, JM; Carrere, N; Maurel, P
      Induction of CYP2C genes in human hepatocytes in primary culture

      DRUG METABOLISM AND DISPOSITION
    98. Kuperman, AV; Kalgutkar, AS; Marfat, A; Chambers, RJ; Liston, TE
      Pharmacokinetics and metabolism of a cysteinyl leukotriene-1 receptor antagonist from the heterocyclic chromanol series in rats: In vitro-in vivo correlation, gender-related differences, isoform identification, and comparison with metabolism in human hepatic tissue

      DRUG METABOLISM AND DISPOSITION
    99. Naritomi, Y; Terashita, S; Kimura, S; Suzuki, A; Kagayama, A; Sugiyama, Y
      Prediction of human hepatic clearance from in vivo animal experiments and in vitro metabolic studies with liver microsomes from animals and humans

      DRUG METABOLISM AND DISPOSITION
    100. Kalvass, JC; Tess, DA; Giragossian, C; Linhares, MC; Maurer, TS
      Influence of microsomal concentration on apparent intrinsic clearance: Implications for scaling in vitro data

      DRUG METABOLISM AND DISPOSITION


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Documento generato il 18/02/20 alle ore 11:42:48