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La ricerca find articoli where soggetti phrase all words 'DRUG DEVELOPMENT' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 433 riferimenti
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    1. Leonard, KA; Deisseroth, AB; Austin, DJ
      Combinatorial chemistry in cancer drug development

      CANCER JOURNAL
    2. White, R; Rusconi, C; Scardino, E; Wolberg, A; Lawson, J; Hoffman, M; Sullenger, B
      Generation of species cross-reactive aptamers using "toggle" SELEX

      MOLECULAR THERAPY
    3. Sponer, G
      Prolongation of repolarization in pre-clinical investigations and phase I/II clinical trials: what should be done?

      EUROPEAN HEART JOURNAL SUPPLEMENTS
    4. Morganroth, J
      Focus on issues in measuring and interpreting changes in the QTc interval duration

      EUROPEAN HEART JOURNAL SUPPLEMENTS
    5. Bonnekoh, B; Bockelmann, R; Ambach, A; Gollnick, H
      Dithranol and dimethylfumarate suppress the interferon-gamma-induced up-regulation of cytokeratin 17 as a putative psoriasis autoantigen in vitro

      SKIN PHARMACOLOGY AND APPLIED SKIN PHYSIOLOGY
    6. Winstanley, P
      Chlorproguanil-dapsone (LAPDAP) for uncomplicated falciparum malaria

      TROPICAL MEDICINE & INTERNATIONAL HEALTH
    7. Emre, M; Qizilbash, N
      Experimental approaches and drugs in development for the treatment of dementia

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    8. Ahmad, N; Adhami, VM; Afaq, F; Feyes, DK; Mukhtar, H
      Resveratrol causes WAF-l/p21-mediated G(1)-phase arrest of cell cycle and induction of apoptosis in human epidermoid carcinoma A431 cells

      CLINICAL CANCER RESEARCH
    9. Moresco, RM; Messa, C; Lucignani, G; Rizzo, G; Todde, S; Gilardi, MC; Grimaldi, A; Fazio, F
      Pet in psychopharmacology

      PHARMACOLOGICAL RESEARCH
    10. Barrow, JC; Nantermet, PG; Selnick, HG; Glass, KL; Ngo, PL; Young, MB; Pellicore, JM; Breslin, MJ; Hutchinson, JH; Freidinger, RM; Condra, C; Karczewski, J; Bednar, RA; Gaul, SL; Stern, A; Gould, R; Connolly, TM
      Discovery and initial structure-activity relationships of trisubstituted ureas as thrombin receptor (PAR-1) antagonists

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    11. Garner, P; Sherry, B; Moilanen, S; Huang, YM
      In vitro stability of alpha-helical peptide nucleic acids (alpha PNAs)

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    12. Schellens, JHM; Dombernowsky, P; Cassidy, J; Epelbaum, R; Dirix, L; Cox, EH; Wanders, J; Calabresi, F; Paridaens, R; Monfardini, S; Wolff, J; Loos, WJ; Verweij, J; Pavlidis, N; Hanauske, AR
      Population pharmacokinetics and dynamics in phase II studies of the novel bioreductive alkylating cytotoxic indoloquinone EO9

      ANTI-CANCER DRUGS
    13. Witte, MC; Montcouquiol, M; Corwin, JT
      Regeneration in avian hair cell epithelia: identification of intracellularsignals required for S-phase entry

      EUROPEAN JOURNAL OF NEUROSCIENCE
    14. Raza, M; Shaheen, F; Choudhary, M; Suria, A; Atta-ur-Rahman; Sombati, S; DeLorenzo, RJ
      Anticonvulsant activities of the FS-1 subfraction isolated from roots of Delphinium denudatum

      PHYTOTHERAPY RESEARCH
    15. Lehr, CM
      In vitro intestinal and alveolar epithelium cultures in drug research

      ALTEX-ALTERNATIVEN ZU TIEREXPERIMENTEN
    16. Lo, D; Hilbush, B; Sutcliffe, JG
      TOGA analysis of gene expression to accelerate target development

      EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
    17. Gomeni, R; Bani, M; D'Angeli, C; Corsi, M; Bye, A
      Computer-assisted drug development (CADD): an emerging technology for designing first-time-in-man and proof-of-concept studies from preclinical experiments

      EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
    18. Aarons, L; Karlsson, MO; Mentre, F; Rombout, F; Steimer, JL; van Peer, A
      Role of modelling and simulation in Phase I drug development

      EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
    19. Bialer, M; Johannessen, SI; Kupferberg, HJ; Levy, RH; Loiseau, P; Perucca, E
      Progress report on new antiepileptic drugs: a summary of the Fifth Eilat Conference (EILAT V)

      EPILEPSY RESEARCH
    20. Hergovich, N; Singer, E; Agneter, E; Eichler, HG; Graselli, U; Simhandl, C; Jilma, B
      Comparison of the effects of ketamine and memantine on prolactin and cortisol release in men: A randomized, double-blind, placebo-controlled trial

      NEUROPSYCHOPHARMACOLOGY
    21. Zhou, J; Riley, CM; Schowen, RL
      In vitro metabolism studies of the prodrug, 2 ',3 ',5 '-triacetyl-6-azauridine, utilizing an automated analytical system

      JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
    22. Miller, KJ; Bowsher, RR; Celniker, A; Gibbons, J; Gupta, S; Lee, JW; Swanson, SJ; Smith, WC; Weiner, RS
      Workshop on bioanalytical methods validation for macromolecules: Summary report

      PHARMACEUTICAL RESEARCH
    23. Papac, DI; Shahrokh, Z
      Mass spectrometry innovations in drug discovery and development

      PHARMACEUTICAL RESEARCH
    24. Raza, M; Shaheen, F; Choudhary, MI; Sombati, S; Rafiq, A; Suria, A; Rahman, A; DeLorenzo, RJ
      Anticonvulsant activities of ethanolic extract and aqueous fraction isolated from Delphinium denudatum

      JOURNAL OF ETHNOPHARMACOLOGY
    25. Hartvig, P; Bergstrom, M; Langstrom, B
      Use of positron emission tomography in analysing receptor function in vivo

      TOXICOLOGY LETTERS
    26. Newman, RA; Yang, J; Finlay, MRV; Cabral, F; Vourloumis, D; Stephens, LC; Troncoso, P; Wu, XB; Logothetis, CJ; Nicolaou, KC; Navone, NM
      Antitumor efficacy of 26-fluoroepothilone B against human prostate cancer xenografts

      CANCER CHEMOTHERAPY AND PHARMACOLOGY
    27. Saijo, N; Tamura, T; Yamamoto, N; Nishio, K
      New strategies for cancer therapy in the 21st century

      CANCER CHEMOTHERAPY AND PHARMACOLOGY
    28. Sheth, SB; DiCicco, RA; Hursting, MJ; Montague, T; Jorkasky, DK
      Interpreting the International Normalized Ratio (INR) in individuals receiving argatroban and warfarin

      THROMBOSIS AND HAEMOSTASIS
    29. Hasbargen, U; Reber, D; Versmold, H; Schulze, A
      Growth and development of children to 4 years of age after repeated antenatal steroid administration

      EUROPEAN JOURNAL OF PEDIATRICS
    30. Grahnen, A; Karlsson, MO
      Concentration-controlled or effect-controlled trials - Useful alternativesto conventional dose-controlled trials?

      CLINICAL PHARMACOKINETICS
    31. Bellissant, E; Giudicelli, JF
      Pharmacokinetic-pharmacodynamic model for perindoprilat regional haemodynamic effects in healthy volunteers and in congestive heart failure patients

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    32. Jonsson, E; Friberg, LE; Karlsson, MO; Hassan, SB; Nygren, P; Kristensen, J; Tholander, B; Binderup, L; Larsson, R
      In vivo activity of CHS 828 on hollow-fibre cultures of primary human tumour cells from patients

      CANCER LETTERS
    33. Shapiro, HM
      Multiparameter flow cytometry of bacteria: Implications for diagnostics and therapeutics

      CYTOMETRY
    34. Taylor, JLS; Rabe, T; McGaw, LJ; Jager, AK; van Staden, J
      Towards the scientific validation of traditional medicinal plants

      PLANT GROWTH REGULATION
    35. Agerso, H; Ynddal, L; Sogaard, B; Zdravkovic, M
      Pharmacokinetic and pharmacodynamic modeling of NN703, a growth hormone secretagogue, after a single po dose to human volunteers

      JOURNAL OF CLINICAL PHARMACOLOGY
    36. Burns, HD; Hamill, TG; Eng, WS; Hargreaves, R
      Chapter 26. PET ligands for assessing receptor occupancy in vivo

      ANNUAL REPORTS IN MEDICINAL CHEMISTRY, VOL 36
    37. Scolnick, EM; Slater, EE; Williams, GW
      "Natural history" clinical trials: An enduring contribution to modern medical practice

      ADVANCES IN PROTEIN CHEMISTRY, VOL 56
    38. Sass, HM
      Do we need new clnical ethical models in medical research?

      WIENER KLINISCHE WOCHENSCHRIFT
    39. Marona, H; Pekala, E; Filipek, B; Maciag, D; Szneler, E
      Pharmacological properties of some aminoalkanolic derivatives of xanthone

      PHARMAZIE
    40. Pandeya, SN; Sriram, D; Yogeeswari, P; Stables, JP
      Anticonvulsant and neurotoxicity evaluation of 5-(un)-substituted isatinimino derivatives

      PHARMAZIE
    41. Kennedy, MA
      What does the human genome project mean for medicine?

      NEW ZEALAND MEDICAL JOURNAL
    42. Fischer, W; Kittner, H; Regenthal, R; Malinowska, B; Schlicker, E
      Anticonvulsant and sodium channel blocking activity of higher doses of clenbuterol

      NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
    43. Kinghorn, AD
      Pharmacognosy in the 21st century

      JOURNAL OF PHARMACY AND PHARMACOLOGY
    44. Srinivas, NR; Barbhaiya, RH; Midha, KK
      Enantiomeric drug development: Issues, considerations, and regulatory requirements

      JOURNAL OF PHARMACEUTICAL SCIENCES
    45. Steegborn, C; Laber, B; Messerschmidt, A; Huber, R; Clausen, T
      Crystal structures of cystathionine gamma-synthase inhibitor complexes rationalize the increased affinity of a novel inhibitor

      JOURNAL OF MOLECULAR BIOLOGY
    46. Versees, W; Decanniere, K; Pelle, R; Depoorter, J; Brosens, E; Parkin, DW; Steyaert, J
      Structure and function of a novel purine specific nucleoside hydrolase from Trypanosoma vivax

      JOURNAL OF MOLECULAR BIOLOGY
    47. Madsen, U; Brauner-Osborne, H; Frydenvang, K; Hvene, L; Johansen, TN; Nielsen, B; Sanchez, C; Stensbol, TB; Bischoff, F; Krogsgaard-Larsen, P
      Synthesis and pharmacology of 3-isoxazolol amino acids as selective antagonists at group I metabotropic glutamic acid receptors

      JOURNAL OF MEDICINAL CHEMISTRY
    48. Swann, E; Barraja, P; Oberlander, AM; Gardipee, WT; Hudnott, AR; Beall, HD; Moody, CJ
      Indolequinone antitumor agents: Correlation between quinone structure and rate of metabolism by recombinant human NAD(P)H : quinone oxidoreductase. Part 2

      JOURNAL OF MEDICINAL CHEMISTRY
    49. Blanchet, JS; Valmori, D; Dufau, I; Ayyoub, M; Nguyen, C; Guillaume, P; Monsarrat, B; Cerottini, JC; Romero, P; Gairin, JE
      A new generation of Melan-A/MART-1 peptides that fulfill both increased immunogenicity and high resistance to biodegradation: Implication for molecular anti-melanoma immunotherapy

      JOURNAL OF IMMUNOLOGY
    50. Vis, P; Della Pasqua, O; Kruk, M; Martin, D; Mocaer, E; Danhof, M; Jochemsen, R
      Population pharmacokinetic-pharmacodynamic modelling of S 15535, a 5-MT1A receptor agonist, using a behavioural model in rats

      EUROPEAN JOURNAL OF PHARMACOLOGY
    51. Stensbol, TB; Jensen, HS; Nielsen, B; Johansen, TN; Egebjerg, J; Frydenvang, K; Krogsgaard-Larsen, P
      Stereochemistry and molecular pharmacology of (S)-thio-ATPA, a new potent and selective GluR5 agonist

      EUROPEAN JOURNAL OF PHARMACOLOGY
    52. Kurup, A; Garg, R; Hansch, C
      Comparative QSAR study of tyrosine kinase inhibitors

      CHEMICAL REVIEWS
    53. Parker, TJ; Della Pasqua, OE; Loizillon, E; Chezaubernard, C; Jochemsen, R; Danhof, M
      Pharmacokinetic-pharmacodynamic modelling in the early development phase of anti-psychotics: A comparison of the effects of clozapine, S 16924 and S 18327 in the EEG model in rats

      BRITISH JOURNAL OF PHARMACOLOGY
    54. Choudry, GA; Stewart, PAH; Double, JA; Krul, MRL; Naylor, B; Flannigan, GM; Shah, TK; Brown, JE; Phillips, RM
      A novel strategy for NQO1 (NAD(P)H : quinone oxidoreductase, EC 1.6.99.2) mediated therapy of bladder cancer based on the pharmacological properties of EO9

      BRITISH JOURNAL OF CANCER
    55. Green, MF; Braff, DL
      Translating the basic and clinical cognitive neuroscience of schizophreniato drug development and clinical trials of antipsychotic medications

      BIOLOGICAL PSYCHIATRY
    56. Clarke, PA; Poele, RT; Wooster, R; Workman, P
      Gene expression microarray analysis in cancer biology, pharmacology, and drug development: progress and potential

      BIOCHEMICAL PHARMACOLOGY
    57. Phillips, RM; Burger, AM; Fiebig, HH; Double, JA
      Genotyping of NAD(P)H : quinone oxidoreductase (NQO1) in a panel of human tumor xenografts: relationship between genotype status, NQO1 activity and the response of xenografts to Mitomycin C chemotherapy in vivo

      BIOCHEMICAL PHARMACOLOGY
    58. Winski, SL; Swann, E; Hargreaves, RHJ; Dehn, DL; Butler, J; Moody, CJ; Ross, D
      Relationship between NAD(P)H : quinone oxidoreductase 1 (NQO1) levels in aseries of stably transfected cell lines and susceptibility to antitumor quinones

      BIOCHEMICAL PHARMACOLOGY
    59. Palom, Y; Belcourt, MF; Tang, LQ; Mehta, SS; Sartorelli, AC; Pritsos, CA; Pritsos, KL; Rockwell, S; Tomasz, M
      Bioreductive metabolism of mitomycin C in EMT6 mouse mammary tumor cells: cytotoxic and non-cytotoxic pathways, leading to different types of DNA adducts. The effect of dicumarol

      BIOCHEMICAL PHARMACOLOGY
    60. Beckmann, N; Mueggler, T; Allegrini, PR; Laurent, D; Rudin, M
      From anatomy to the target: Contributions of magnetic resonance imaging topreclinical pharmaceutical research

      ANATOMICAL RECORD
    61. Bartenschlager, R; Lohmann, V
      Replication of the hepatitis C virus

      BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY
    62. Cummings, J
      The role of reductive enzymes in cancer cell resistance to mitomycin C

      DRUG RESISTANCE UPDATES
    63. Destenaves, B; Thomas, F
      New advances in pharmacogenomics

      CURRENT OPINION IN CHEMICAL BIOLOGY
    64. Jain, KK
      An assessment of rufinamide as an anti-epileptic in comparison with other drugs in clinical development

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    65. Gribaldo, L; Malerba, I; Collotta, A; Casati, S; Pessina, A
      Inhibition of CFU-E/BFU-E by 3 '-azido-3 '-deoxythymidine, chlorpropamide,and protoporphirin IX zinc (II): A comparison between direct exposure of progenitor cells and long-term exposure of bone marrow cultures

      TOXICOLOGICAL SCIENCES
    66. Dean, NM; Cooper, SR; Shanahan, W; Taylor, J; Myers, K
      Pharmacology of antisense oligonucleotides

      JOURNAL OF CLINICAL LIGAND ASSAY
    67. Agarwal, C; Sharma, Y; Zhao, JF; Agarwal, R
      A polyphenolic fraction from grape seeds causes irreversible growth inhibition of breast carcinoma MDA-MB468 cells by inhibiting mitogen-activated protein kinases activation and inducing G(1) arrest and differentiation

      CLINICAL CANCER RESEARCH
    68. Cox, K
      Enhancing cancer clinical trial management: Recommendations from a qualitative study of trial participants' experiences

      PSYCHO-ONCOLOGY
    69. Novack, GD
      Financing new drug development in ophthalmology

      JOURNAL OF GLAUCOMA
    70. Cunningham, MJ
      Genomics and proteomics - The new millennium of drug discovery and development

      JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
    71. Gralinski, MR
      The assessment of potential for QT interval prolongation with new pharmaceuticals Impact on drug development

      JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
    72. Price, P
      Monitoring response to treatment in the development of anticancer drugs using PET

      NUCLEAR MEDICINE AND BIOLOGY
    73. Andree, B; Halldin, C; Thorberg, SO; Sandell, J; Farde, L
      Use of PET and the radioligand [Carbonyl-C-11]WAY-100635 in psychotropic drug development

      NUCLEAR MEDICINE AND BIOLOGY
    74. Estrada, E; Pena, A
      In silico studies for the rational discovery of anticonvulsant compounds

      BIOORGANIC & MEDICINAL CHEMISTRY
    75. Otvos, L; Bokonyi, K; Varga, I; Otvos, BI; Hoffmann, R; Ertl, HCJ; Wade, JD; McManus, AM; Craik, D; Bulet, P
      Insect peptides with improved protease-resistance protect mice against bacterial infection

      PROTEIN SCIENCE
    76. Jonsson, E; Dhar, S; Jonsson, B; Nygren, P; Graf, W; Larsson, R
      Differential activity of topotecan, irinotecan and SN-38 in fresh human tumour cells but not in cell lines

      EUROPEAN JOURNAL OF CANCER
    77. Pryor, JL; Redmon, B
      New therapies and delivery mechanisms for treatment of erectile dysfunction

      INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
    78. Heinrich, M
      Ethnobotany and its role in drug development

      PHYTOTHERAPY RESEARCH
    79. Al-Obeidi, FA; Lam, KS
      Development of inhibitors for protein tyrosine kinases

      ONCOGENE
    80. Balant, LP; Balant-Gorgia, EA
      Cultural differences: implications on drug therapy and global drug development

      INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS
    81. Nagata, R; Fukase, H; Rafizadeh-Kabe, JD
      East-West development: understanding the usability and acceptance of foreign data in Japan

      INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS
    82. Argenti, D; Vaccaro, SK; Shah, B; Gillen, MS; Rohatagi, S; Jensen, BK
      Effect of food and gender on the pharmacokinetics of RP 73401, a phosphodiesterase IV inhibitor

      INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS
    83. Smith, DA
      Induction and drug development

      EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
    84. Whitehouse, PJ
      Harmonization of dementia drug guidelines (United States and Europe): A report of the International Working Group for the Harmonization for Dementia Drug Guidelines

      ALZHEIMER DISEASE & ASSOCIATED DISORDERS
    85. Janero, DR; Ewing, JF
      Nitric oxide and postangioplasty restenosis: pathological correlates and therapeutic potential

      FREE RADICAL BIOLOGY AND MEDICINE
    86. Janero, DR
      Nitric oxide (NO)-related pharmaceuticals: Contemporary approaches to therapeutic NO modulation

      FREE RADICAL BIOLOGY AND MEDICINE
    87. Findlay, JWA; Smith, WC; Lee, JW; Nordblom, GD; Das, I; DeSilva, BS; Khan, MN; Bowsher, RR
      Validation of immunoassays for bioanalysis: a pharmaceutical industry perspective

      JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
    88. Brenner, DE
      Multiagent chemopreventive agent combinations

      JOURNAL OF CELLULAR BIOCHEMISTRY
    89. Weihrauch, TR
      Career opportunities for physicians in the pharmaceutical industry

      MEDIZINISCHE KLINIK
    90. Kuhlmann, J
      Tasks of clinical pharmacology in the early phase of drug development

      MEDIZINISCHE KLINIK
    91. Gieschke, R; Steimer, JL
      Pharmacometrics: modelling and simulation tools to improve decision makingin clinical drug development

      EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS
    92. Panchagnula, R; Thomas, NS
      Biopharmaceutics and pharmacokinetics in drug research

      INTERNATIONAL JOURNAL OF PHARMACEUTICS
    93. Holford, NHG; Kimko, HC; Monteleone, JPR; Peck, CC
      Simulation of clinical trials

      ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY
    94. Arledge, T; Freeman, A; Arbuckle, J; Mosteller, M; Manasco, P
      Applications of pharmacogenetics to drug development: The Glaxo Wellcome experience

      DRUG METABOLISM REVIEWS
    95. Adams, DJ; Dewhirst, MW; Flowers, JL; Gamcsik, MP; Colvin, OM; Manikumar, G; Wani, MC; Wall, ME
      Camptothecin analogues with enhanced antitumor activity at acidic pH

      CANCER CHEMOTHERAPY AND PHARMACOLOGY
    96. Fuhrman, S; Cunningham, MJ; Wen, XL; Zweiger, G; Seilhamer, JJ; Somogyi, R
      The application of Shannon entropy in the identification of putative drug targets

      BIOSYSTEMS
    97. Zisapel, N
      Development of a melatonin-based formulation for the treatment of insomniain the elderly

      DRUG DEVELOPMENT RESEARCH
    98. Fry, DW
      Site-directed irreversible inhibitors of the erbB family of receptor tyrosine kinases as novel chemotherapeutic agents for cancer

      ANTI-CANCER DRUG DESIGN
    99. Pandeya, SN; Yogeeswari, P; Stables, JP
      Synthesis and anticonvulsant activity of 4-bromophenyl substituted aryl semicarbazones

      EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
    100. Sanger-van de Griend, CE
      Enantiomeric separation of alanyl and leucyl dipeptides by capillary electrophoresis with cyclodextrins as chiral selectors

      ELECTROPHORESIS


ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/10/20 alle ore 18:58:42