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Functional effect of adeno-associated virus mediated gene transfer of aromatic L-amino acid decarboxylase into the striatum of 6-OHDA-lesioned rats
MOLECULAR THERAPY
The oxidation of 6-hydroxydopamine in aqueous solution. Part 2. Speciationand product distribution with iron(III) as oxidant
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2
Pathophysiology of levodopa-induced dyskinesia: Potential for new therapies
NATURE REVIEWS NEUROSCIENCE
Identification and characterization of an aromatic amino acid decarboxylase from the filarial nematode, Dirofilaria immitis
BIOLOGICAL CHEMISTRY
Enhanced associated movements in the contralateral limbs elicited by briskvoluntary contraction in choreic disorders
CLINICAL NEUROPHYSIOLOGY
Cysteine and indole derivatives as markers for malignant melanoma
JOURNAL OF CHROMATOGRAPHY B
Salsolinol, a naturally occurring tetrahydroisoquinoline alkaloid, inducesDNA damage and chromosomal aberrations in cultured Chinese hamster lung fibroblast cells
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
Stereoselective and manganese-dependent sulfation and urinary excretion ofD-form and L-form meta-tyrosine O-sulfate by Sprague-Dawley rats
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
Restless legs syndrome
SPINAL CORD
Dopa decarboxylase gene polymorphisms and attention deficit hyperactivity disorder (ADHD): no evidence for association in the Irish population
MOLECULAR PSYCHIATRY
Levodopa prolongs life expectancy and is non-toxic to substantia nigra
PARKINSONISM & RELATED DISORDERS
Motor fluctuations and dyskinesia in Parkinson's disease
PARKINSONISM & RELATED DISORDERS
Dystonia and parkinsonism
PARKINSONISM & RELATED DISORDERS
The long-term response to levodopa in dopa-responsive dystonia
PARKINSONISM & RELATED DISORDERS
Familial occurrence of Parkinson's disease in a community-based case-control study
PARKINSONISM & RELATED DISORDERS
Neonatal iron potentiates adult MPTP-induced neurodegenerative and functional deficits
PARKINSONISM & RELATED DISORDERS
EFNS task force on molecular diagnosis of neurologic disorders - Guidelines for the molecular diagnosis of inherited neurologic diseases - First of two parts
EUROPEAN JOURNAL OF NEUROLOGY
Health-related quality of life and healthcare utilisation in patients withParkinson's disease - Impact of motor fluctuations and dyskinesias
PHARMACOECONOMICS
Determination of the influence of borate ion on the degradation of L-alpha-methyldopa using RP-HPLC with photodiode array detection
JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES
A highly sensitive method for the determination of protein bound 3,4-dihydroxyphenylalanine as a marker for post-translational protein hydroxylation in human tissues ex vivo
FREE RADICAL RESEARCH
Re: Phylogenetic relationships in Sphingidae (Insecta : Lepidoptera): Initial evidence from two nuclear genes
MOLECULAR PHYLOGENETICS AND EVOLUTION
Phylogenetic utility of the major opsin in bees (Hymenoptera : apoidea): Areassessment
MOLECULAR PHYLOGENETICS AND EVOLUTION
Phylogenetic utility of mitochondrial COI and nuclear Gpdh genes in Drosophila
MOLECULAR PHYLOGENETICS AND EVOLUTION
Enhanced or impaired cognitive function in Parkinson's disease as a function of dopaminergic medication and task demands
CEREBRAL CORTEX
Monitoring of L-dopa concentrations in Parkinson's disease
PHARMACOLOGICAL RESEARCH
A new strategy for site-specific protein modification: Analysis of a Tat peptide - TAR RNA interaction
BIOCONJUGATE CHEMISTRY
Application of L-dopa as an electroactive ligand for indirect determination of aluminum in biological samples by differential pulse voltammetry
ELECTROANALYSIS
Skin pigmentation enhancers
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
Contributions of PET and SPECT to the understanding of the pathophysiologyof Parkinson's disease
NEUROPHYSIOLOGIE CLINIQUE-CLINICAL NEUROPHYSIOLOGY
Upregulation of striatal preproenkephalin gene expression occurs before the appearance of parkinsonian signs in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine monkeys
NEUROBIOLOGY OF DISEASE
Kinetics of the metabolism of four PET radioligands in living minipigs
NUCLEAR MEDICINE AND BIOLOGY
Rat marrow stromal cells rapidly transduced with a self-inactivating retrovirus synthesize L-DOPA in vitro
GENE THERAPY
Isolation and developmental expression of two nuclear receptors, MHR4 and beta FTZ-F1, in the tobacco hornworm, Manduca sexta
INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
Aedes aegypti peroxidase gene characterization and developmental expression
INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
Cloning and characterization of a dopachrome conversion enzyme from the yellow fever mosquito, Aedes aegypti
INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
Dopa decarboxylase exhibits low pH half-transaminase and high pH oxidativedeaminase activities toward serotonin (5-hydroxytryptamine)
PROTEIN SCIENCE
Reactivity of peptidyl-tyrosine to hydroxylation and cross-linking
PROTEIN SCIENCE
Fluoxetine reduces L-DOPA-derived extracellular DA in the 6-OHDA-lesioned rat striatum?
NEUROREPORT
6-hydroxydopamine increases hydroxyl free radical production and DNA damage in rat striatum
NEUROREPORT
Damage to nuclear DNA in Lewy body disease
NEUROREPORT
GDNF reverses priming for dyskinesia in MPTP-treated, L-DOPA-primed commonmarmosets
EUROPEAN JOURNAL OF NEUROSCIENCE
Rod photopigment deficits in albinos are specific to mammals and arise during retinal development
VISUAL NEUROSCIENCE
Ocular albinism type 1: More than meets the eye
PIGMENT CELL RESEARCH
Melanosynthesis, differentiation, and apoptosis in Kupffer cells from Ranaesculenta
PIGMENT CELL RESEARCH
Chromium(VI) reduction by catechol(amine)s results in DNA cleavage in vitro: Relevance to chromium genotoxicity
CHEMICAL RESEARCH IN TOXICOLOGY
The hydrogen peroxide/copper ion system, but not other metal-catalyzed oxidation systems, produces protein-bound dityrosine
FREE RADICAL BIOLOGY AND MEDICINE
Oxidative DNA damage and cytotoxicity induced by copper-stimulated redox cycling of salsolinol, a neurotoxic tetrahydroisoquinoline alkaloid
FREE RADICAL BIOLOGY AND MEDICINE
LY293558, an AMPA glutamate receptor antagonist, prevents and reverses levodopa-induced motor alterations in parkinsonian rats
SYNAPSE
Loss of metabolites from monkey striatum during PET with FDOPA
SYNAPSE
Acute neuroleptic stimulates DOPA decarboxylase in porcine brain in vivo
SYNAPSE
Detection of response to COMT inhibition in FDOPA PET in advanced Parkinson's disease requires prolonged imaging
SYNAPSE
Motor stimulant effects of the adenosine A(2A) receptor antagonist SCH 58261 do not develop tolerance after repeated treatments in 6-hydroxydopamine-lesioned rats
SYNAPSE
The influence of three months of methylphenidate treatment on platelet-poor plasma biogenic amine levels in boys with attention deficit hyperactivitydisorder
HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL
Sleep laboratory studies in periodic limb movement disorder (PLMD) patients as compared with normals and acute effects of ropinirole
HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL
Long-term follow-up on restless legs syndrome patients treated with opioids
MOVEMENT DISORDERS
Novel observations with FDOPA-PET imaging after early nigrostriatal damage
MOVEMENT DISORDERS
Rate of progression in Parkinson's disease: A 6-[F-18]fluoro-L-dopa PET study
MOVEMENT DISORDERS
Antiparkinsonian activity and dyskinesia risk of ropinirole and L-DOPA combination therapy in drug naive MPTP-lesioned common marmosets (Callithrix jacchus)
MOVEMENT DISORDERS
Neural mechanisms underlying peak-dose dyskinesia induced by levodopa and apomorphine are distinct: Evidence from the effects of the alpha(2) adrenoceptor antagonist idazoxan
MOVEMENT DISORDERS
Idazoxan, an alpha-2 antagonist, and L-DOPA-induced dyskinesias in patients with Parkinson's disease
MOVEMENT DISORDERS
Chronic L-DOPA administration is not toxic to the remaining dopaminergic nigrostriatal neurons, but instead may promote their functional recovery, inrats with partial 6-OHDA or FeCl3 nigrostriatal lesions
MOVEMENT DISORDERS
Reliability and validity of a new global dyskinesia rating scale in the MPTP-lesioned non-human primate
MOVEMENT DISORDERS
Changes of gastric lipase activity after ethanol and indomethacin administration: Influence of pretreatment with allopurinol, pentoxifylline and L-DOPA
PHYSIOLOGICAL RESEARCH
Increased pineal Fdopa uptake is related to severity of Parkinson's disease - A PET study
JOURNAL OF PINEAL RESEARCH
Dystonia and its disorders
NEUROLOGIC CLINICS
Sleep disorders
NEUROLOGIC CLINICS
Flow Injection Determination of levodopa in tablets using a solid-phase reactor containing lead(IV) dioxide immobilized
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
A pharmacokinetic model to predict the PK interaction of l-dopa and benserazide in rats
PHARMACEUTICAL RESEARCH
Cellular localization of tyrosine decarboxylase expression in transgenic opium poppy and tobacco
PLANT CELL REPORTS
Spin labelled nitrosoureas and triazenes and their non-labelled clinicallyused analogues - a comparative study on their physicochemical properties and antimelanomic effects
INTERNATIONAL JOURNAL OF PHARMACEUTICS
Effects of gas composition on the cell growth and L- DOPA production in the suspension culture of Stizolobium hassjoo
JOURNAL OF THE CHINESE INSTITUTE OF CHEMICAL ENGINEERS
Parkinson's diseasetherapy: treatment of early and late disease
CHINESE MEDICAL JOURNAL
Levodopa induces dyskinesias in normal squirrel monkeys
ANNALS OF NEUROLOGY
Subclinical dopaminergic dysfunction in asymptomatic Parkinson's disease patients' relatives with a decreased sense of smell
ANNALS OF NEUROLOGY
Positron emission tomographic analysis of the nigrostriatal dopaminergic system in familial parkinsonism associated with mutations in the parkin gene
ANNALS OF NEUROLOGY
L-DOPA decarboxylase association with membranes in mouse brain
NEUROCHEMICAL RESEARCH
Dyskinesia: L-dopa-induced and tardive dyskinesia
CLINICAL NEUROPHARMACOLOGY
Methylphenidate increases the motor effects of L-dopa in Parkinson's disease: A pilot study
CLINICAL NEUROPHARMACOLOGY
The effects of different repeated doses of entacapone on the pharmacokinetics of L-Dopa and on the clinical response to L-Dopa in Parkinson's disease
CLINICAL NEUROPHARMACOLOGY
Levodopa-induced drowsiness in healthy volunteers: Results of a choice reaction time test combined with a subjective evaluation of sedation
CLINICAL NEUROPHARMACOLOGY
The pharmacokinetic profile of the "first ever" oral dose of levodopa in de novo patients with Parkinson's disease
CLINICAL NEUROPHARMACOLOGY
Catechol-O-methyltransferase decreases levodopa toxicity in vitro
CLINICAL NEUROPHARMACOLOGY
Synthesis of carbon-14 labeled [1-C-14]-, and [2-C-14]-L-tyrosine
JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS
Drug treatment effects on disease progression
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY
F-18-DOPA positron emission tomography for tumour detection in patients with medullary thyroid carcinoma and elevated calcitonin levels
EUROPEAN JOURNAL OF NUCLEAR MEDICINE
Molecular analysis and long-term follow-up of patients with different forms of 6-pyruvoyl-tetrahydropterin synthase deficiency
EUROPEAN JOURNAL OF PEDIATRICS
New therapies for Parkinson's disease
JOURNAL OF NEUROLOGY
Chronic bilateral pallidal stimulation and levodopa do not improve gait inthe same way in Parkinson's disease: a study using video motion analysis system
JOURNAL OF NEUROLOGY
Synthesis, spectroscopic and voltammetric studies of mixed-ligand copper(II) complexes of amino acids
TRANSITION METAL CHEMISTRY
Rapid reversed-phase high performance liquid chromatographic method for the quantification of L-Dopa (L-3,4-dihydroxyphenylalanine), non-methylated and methylated tetrahydroisoquinoline compounds from Mucuna beans
FOOD CHEMISTRY
Autoradiographic studies using L-[C-14]DOPA and L-[H-3]DOPA reveal regional NA(+)-dependent uptake of the neurotransmitter candidate L-DOPA in the CNS
NEUROSCIENCE
Mechanisms of the effects of exogenous levodopa on the dopamine-denervatedstriatum
NEUROSCIENCE
Strand scission in DNA induced by 5-hydroxytryptamine (Serotonin) in the presence of copper ions
NEUROSCIENCE LETTERS
Decrease of methionine and S-adenosylmethionine and increase of homocysteine in treated patients with Parkinson's disease
NEUROSCIENCE LETTERS
Establishment of L-3,4-dihydroxyphenilalaninde-induced pharmacological dementia model mouse
NEUROSCIENCE LETTERS
The imidazoline receptor ligand 2-(2-benzofuranyl)-2-imidazoline is a dopamine-releasing agent in the rat striatum in vivo
NEUROSCIENCE LETTERS
DOPA cyclohexyl ester, a competitive DOPA antagonist, protects glutamate release and resultant delayed neuron death by transient ischemia in hippocampus CA1 of conscious rats
NEUROSCIENCE LETTERS
Changes in vesicular monoamine transporter (VMAT2) and synaptophysin in rat substantia nigra and prefrontal cortex induced by psychotropic drugs
NEUROPSYCHOBIOLOGY
Chronic high dose L-dopa treatment does not alter the levels of dopamine D-1, D-2 or D-3 receptor in the striatum of normal monkeys: an autoradiographic study
JOURNAL OF NEURAL TRANSMISSION
[I-123]FP-CIT SPECT is a useful method to monitor the rate of dopaminergicdegeneration in early-stage Parkinson's disease
JOURNAL OF NEURAL TRANSMISSION