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La ricerca find articoli where soggetti phrase all words 'DNA-DAMAGE RESPONSE' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 115 riferimenti
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    1. Zhu, Y; Xiao, W
      Two alternative cell cycle checkpoint pathways differentially control DNA damage-dependent induction of MAG1 and DDI1 expression in yeast

      MOLECULAR GENETICS AND GENOMICS
    2. McKinnon, PJ
      Ataxia telangiectasia: new neurons and ATM

      TRENDS IN MOLECULAR MEDICINE
    3. Futaki, M; Liu, JM
      Chromosomal breakage syndromes and the BRCA1 genome surveillance complex

      TRENDS IN MOLECULAR MEDICINE
    4. Fry, MJ
      Phosphoinositide 3-kinase signalling in breast cancer: how big a role might it play?

      BREAST CANCER RESEARCH
    5. Deng, CX
      Tumorigenesis as a consequence of genetic instability in Brca1 mutant mice

      MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
    6. Garcia-Higuera, I; Taniguchi, T; Ganesan, S; Meyn, MS; Timmers, C; Hejna, J; Grompe, M; D'Andrea, AD
      Interaction of the fanconi anemia proteins and BRCA1 in a common pathway

      MOLECULAR CELL
    7. Nathanson, KN; Wooster, R; Weber, BL
      Breast cancer genetics: What we know and what we need

      NATURE MEDICINE
    8. Garcia-Perez, MA; Allende, LM; Corell, A; Paz-Artal, E; Varela, P; Lopez-Goyanes, A; Garcia-Martin, F; Vazquez, R; Sotoca, A; Arnaiz-Villena, A
      Role of Nijmegen breakage syndrome protein in specific T-lymphocyte activation pathways

      CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY
    9. Rhodes, N; Gilmer, TM; Lansing, TJ
      Expression and purification of active recombinant ATM protein from transiently transfected mammalian cells

      PROTEIN EXPRESSION AND PURIFICATION
    10. Shin, BA; Ahn, KY; Kook, H; Koh, JT; Kang, IC; Lee, HC; Kim, KK
      Overexpressed human RAD50 exhibits cell death in a p21 (WAF1/CIP1)-dependent manner: Its potential utility in local gene therapy of tumor

      CELL GROWTH & DIFFERENTIATION
    11. Sylvain, V; LaFarge, S; Bignon, YJ
      Molecular pathways involved in response to ionizing radiation of ID-8 mouse ovarian cancer cells expressing exogenous full-length Brca1 or truncated Brca1 mutant

      INTERNATIONAL JOURNAL OF ONCOLOGY
    12. Welcsh, PL; King, MC
      BRCA1 and BRCA2 and the genetics of breast and ovarian cancer

      HUMAN MOLECULAR GENETICS
    13. Kerr, P; Ashworth, A
      New complexities for BRCA1 and BRCA2

      CURRENT BIOLOGY
    14. Ranganathan, V; Heine, WF; Ciccone, DN; Rudolph, KL; Wu, XH; Chang, S; Hai, H; Ahearn, IM; Livingston, DM; Resnick, I; Rosen, F; Seemanova, E; Jarolim, P; DePinho, RA; Weaver, DT
      Rescue of a telomere length defect of Nijmegen breakage syndrome cells requires NBS and telomerase catalytic subunit

      CURRENT BIOLOGY
    15. Brodie, SG; Xu, XL; Qiao, WH; Li, WM; Cao, L; Deng, CX
      Multiple genetic changes are associated with mammary tumorigenesis in Brca1 conditional knockout mice

      ONCOGENE
    16. Lafarge, S; Sylvain, V; Ferrara, M; Bignon, YJ
      Inhibition of BRCA1 leads to increased chemoresistance to microtubule-interfering agents, an effect that involves the JNK pathway

      ONCOGENE
    17. Mullan, PB; Quinn, JE; Gilmore, PM; McWilliams, S; Andrews, H; Gervin, C; McCabe, N; McKenna, S; White, P; Song, YH; Maheswaran, S; Liu, E; Haber, DA; Johnston, PG; Harkin, DP
      BRCA1 and GADD45 mediated G2/M cell cycle arrest in response to antimicrotubule agents

      ONCOGENE
    18. Bartkova, J; Falck, J; Rajpert-De Meyts, E; Skakkebaek, NE; Lukas, J; Bartek, J
      Chk2 tumour suppressor protein in human spermatogenesis and testicular germ-cell tumours

      ONCOGENE
    19. Orelli, BJ; Logsdon, JM; Bishop, DK
      Nine novel conserved motifs in BRCA1 identified by the chicken orthologue

      ONCOGENE
    20. Pavelic, K; Gall-Troselj, K
      Recent advances in molecular genetics of breast cancer

      JOURNAL OF MOLECULAR MEDICINE-JMM
    21. Randrianarison, V; Marot, D; Foray, N; Cabannes, J; Meret, V; Connault, E; Vitrat, N; Opolon, P; Perricaudet, M; Feunteun, J
      BRCA1 carries tumor suppressor activity distinct from that of p53 and p21

      CANCER GENE THERAPY
    22. Kraakman-van der Zwet, M; Overkamp, WJI; Jaspers, NGJ; Natarajan, AT; Lohman, PHM; Zdzienicka, MZ
      Complementation of chromosomal aberrations in AT/NBS hybrids: inadequacy of RDS as an endpoint in complementation studies with immortal NBS cells

      MUTATION RESEARCH-DNA REPAIR
    23. Tachibana, A; Tatsumi, K; Furuno-Fukushi, I; Sasaki, MS
      High frequency of deletions at the hypoxanthine-guanine phosphoribosyltransferase locus in an ataxia-telangiectasia lymphoblastoid cell line irradiated with gamma-rays

      JAPANESE JOURNAL OF CANCER RESEARCH
    24. Hu, FH; Alcasabas, AA; Elledge, SJ
      Asf1 links Rad53 to control of chromatin assembly

      GENES & DEVELOPMENT
    25. Abraham, RT
      Cell cycle checkpoint signaling through the ATM and ATR kinases

      GENES & DEVELOPMENT
    26. D'Amours, D; Jackson, SP
      The yeast Xrs2 complex functions in S phase checkpoint regulation

      GENES & DEVELOPMENT
    27. Crompton, NEA; Shi, YQ; Emery, GC; Wisser, L; Blattmann, H; Maier, A; Li, L; Schindler, D; Ozsahin, H; Ozsahin, M
      Sources of variation in patient response to radiation treatment

      INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
    28. Bishop, AJR; Schiestl, RH
      Homologous recombination as a mechanism of carcinogenesis

      BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
    29. Mullan, PB; McWilliams, S; Quinn, J; Andrews, H; Gilmore, P; McCabe, N; McKenna, S; Harkin, DP
      Uncovering BRCA1-regulated signalling pathways by microarray-based expression profiling

      BIOCHEMICAL SOCIETY TRANSACTIONS
    30. Gatti, RA
      The inherited basis of human radiosensitivity

      ACTA ONCOLOGICA
    31. Desai-Mehta, A; Cerosaletti, KM; Concannon, P
      Distinct functional domains of nibrin mediate Mre11 binding, focus formation, and nuclear localization

      MOLECULAR AND CELLULAR BIOLOGY
    32. Xu, B; Kim, ST; Kastan, MB
      Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation

      MOLECULAR AND CELLULAR BIOLOGY
    33. Hartsuiker, E; Vaessen, E; Carr, AM; Kohli, J
      Fission yeast Rad50 stimulates sister chromatid recombination and links cohesion with repair

      EMBO JOURNAL
    34. Myung, KJ; Datta, A; Kolodner, RD
      Suppression of spontaneous chromosomal rearrangements by S phase checkpoint functions in Saccharomyces cerevisiae

      CELL
    35. Shiloh, Y; Kastan, MB
      ATM: Genome stability, neuronal development, and cancer cross paths

      ADVANCES IN CANCER RESEARCH, VOL 83
    36. Zhu, WG; Seno, JD; Beck, BD; Dynlacht, JR
      Translocation of MRE11 from the nucleus to the cytoplasm as a mechanism ofradiosensitization by heat

      RADIATION RESEARCH
    37. Ruffner, H; Joazeiro, CAP; Hemmati, D; Hunter, T; Verma, IM
      Cancer-predisposing mutations within the RING domain of BRCA1: Loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    38. Xia, F; Taghian, DG; DeFrank, JS; Zeng, ZC; Willers, H; Iliakis, G; Powell, SN
      Deficiency of human BRCA2 leads to impaired homologous recombination but maintains normal nonhomologous end joining

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    39. Maraschio, P; Danesino, C; Antoccia, A; Ricordy, R; Tanzarella, C; Varon, R; Reis, A; Besana, D; Guala, A; Tiepolo, L
      A novel mutation and novel features in Nijmegen breakage syndrome

      JOURNAL OF MEDICAL GENETICS
    40. Perez-Valles, A; Martorell-Cebollada, M; Nogueira-Vazquez, E; Garcia-Garcia, JA; Fuster-Diana, E
      The usefulness of antibodies to the BRCA1 protein in detecting the mutatedBRCA1 gene. An immunohistochemical study

      JOURNAL OF CLINICAL PATHOLOGY
    41. Xiao, J; Liu, CC; Chen, PL; Lee, WH
      RINT-1, a novel Rad50-interacting protein, participates in radiation-induced G(2)/M checkpoint control

      JOURNAL OF BIOLOGICAL CHEMISTRY
    42. Chiba, N; Parvin, JD
      Redistribution of BRCA1 among four different protein complexes following replication blockage

      JOURNAL OF BIOLOGICAL CHEMISTRY
    43. Stewart, GS; Last, JIK; Stankovic, T; Haites, N; Kidd, AMJ; Byrd, PJ; Taylor, AMR
      Residual ataxia telangiectasia mutated protein function in cells from ataxia telangiectasia patients, with 5762ins137 and 7271T -> G mutations, showing a less severe phenotype

      JOURNAL OF BIOLOGICAL CHEMISTRY
    44. Aprelikova, O; Pace, AJ; Fang, B; Koller, BH; Liu, ET
      BRCA1 is a selective co-activator of 14-3-3 sigma gene transcription in mouse embryonic stem cells

      JOURNAL OF BIOLOGICAL CHEMISTRY
    45. Gatei, M; Zhou, BD; Hobson, K; Scott, S; Young, D; Khanna, KH
      Ataxia telangiectasia mutated (ATM) kinase and ATM and Rad3 related kinasemediate phosphorylation of Brca1 at distinct and overlapping sites - In vivo assessment using phospho-specific antibodies

      JOURNAL OF BIOLOGICAL CHEMISTRY
    46. Dimitrov, SD; Matouskova, E; Forejt, J
      Expression of BRCA1, NBR1 and NBR2 genes in human breast cancer cells

      FOLIA BIOLOGICA
    47. Lee, SB; Kim, SH; Bell, DW; Wahrer, DCR; Schiripo, TA; Jorczak, MM; Sgroi, DC; Garber, JE; Li, FP; Nichols, KE; Varley, JM; Godwin, AK; Shannon, KM; Harlow, E; Haber, DA
      Destabilization of CHK2 by a missense mutation associated with Li-Fraumenisyndrome

      CANCER RESEARCH
    48. Fishel, R
      The selection for mismatch repair defects in hereditary nonpolyposis colorectal cancer: Revising the mutator hypothesis

      CANCER RESEARCH
    49. Kim, NG; Choi, YR; Baek, MJ; Kim, YH; Kang, H; Kim, NK; Min, JS; Kim, H
      Frameshift mutations at coding mononucleotide repeats of the hRAD50 gene in gastrointestinal carcinomas with microsatellite instability

      CANCER RESEARCH
    50. Teraoka, SN; Malone, KE; Doody, DR; Suter, NM; Ostrander, EA; Daling, JR; Concannon, P
      Increased frequency of ATM mutations in breast carcinoma patients with early onset disease and positive family history

      CANCER
    51. Angele, S; Taniere, P; Hall, J
      What do we know about ATM protein expression in breast tissue?

      BULLETIN DU CANCER
    52. Slebos, RJC; Taylor, JA
      A novel host cell reactivation assay to assess homologous recombination capacity in human cancer cell lines

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    53. Green, DR; Schuler, M
      T cell development: Some cells get all the breaks

      NATURE IMMUNOLOGY
    54. Mak, TW; Hakem, A; McPherson, JP; Shehabeldin, A; Zablocki, E; Migon, E; Duncan, GS; Bouchard, D; Wakeham, A; Cheung, A; Karaskova, J; Sarosi, I; Squire, J; Marth, J; Hakem, R
      BracI required for T cell linage development but not TCR loci rearrangement

      NATURE IMMUNOLOGY
    55. Jeffy, BD; Chen, EJ; Gudas, JM; Romagnolo, DF
      Disruption of cell cycle kinetics by benzo[a]pyrene: Inverse expression patterns of BRCA-1 and p53 in MCF-7 cells arrested in S and G(2)

      NEOPLASIA
    56. Kastan, MB; Lim, DS
      The many substrates and functions of ATM

      NATURE REVIEWS MOLECULAR CELL BIOLOGY
    57. Scully, R
      Role of BRCA gene dysfunction in breast and ovarian cancer predisposition

      BREAST CANCER RESEARCH
    58. Yu, V
      Caretaker Brca1: keeping the genome in the straight and narrow

      BREAST CANCER RESEARCH
    59. Allio, T; Preston, RJ
      Increased sensitivity to chromatid aberration induction by bleomycin and neocarzinostatin results from alterations in a DNA damage response pathway

      MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
    60. Sung, P; Trujillo, KM; Van Komen, S
      Recombination factors of Saccharomyces cerevisiae

      MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
    61. Zheng, L; Pan, HY; Li, S; Flesken-Nikitin, A; Chen, PL; Boyer, TG; Lee, WH
      Sequence-specific transcriptional corepressor function for BRCA1 through anovel zinc finger protein, ZBRK1

      MOLECULAR CELL
    62. Becker-Catania, SG; Chen, G; Hwang, MJ; Wang, ZJ; Sun, X; Sanal, O; Bernatowska-Matuszkiewicz, E; Chessa, L; Lee, EYHP; Gatti, RA
      Ataxia-telangiectasia: Phenotype/genotype studies of ATM protein expression, mutations, and radiosensitivity

      MOLECULAR GENETICS AND METABOLISM
    63. Gatei, M; Young, D; Cerosaletti, KM; Desai-Mehta, A; Spring, K; Kozlov, S; Lavin, MF; Gatti, RA; Concannon, P; Khanna, K
      ATM-dependent phosphorylation of nibrin in response to radiation exposure

      NATURE GENETICS
    64. Laake, K; Jansen, L; Hahnemann, JM; Brondum-Nielsen, K; Lonnqvist, T; Kaariainen, H; Sankila, R; Lahdesmaki, A; Hammarstrom, L; Yuen, J; Tretli, S; Heiberg, A; Olsen, JH; Tucker, M; Kleinerman, R; Borresen-Dale, AL
      Characterization of ATM mutations in 41 Nordic families with ataxia telangiectasia

      HUMAN MUTATION
    65. Unger, MA; Weber, BL
      Recent advances in breast cancer biology

      CURRENT OPINION IN ONCOLOGY
    66. Chien, M; Rinker-Schaeffer, C; Stadler, WM
      A G2/M growth arrest response to low-dose intermittent H2O2 in normal uroepithelial cells

      INTERNATIONAL JOURNAL OF ONCOLOGY
    67. Wilda, M; Demuth, I; Concannon, P; Sperling, K; Hameister, H
      Expression pattern of the Nijmegen breakage syndrome gene, Nbs1, during murine development

      HUMAN MOLECULAR GENETICS
    68. Haber, JE
      Recombination: a frank view of exchanges and vice versa

      CURRENT OPINION IN CELL BIOLOGY
    69. Petrini, JHJ
      The Mre11 complex and ATM: collaborating to navigate S phase

      CURRENT OPINION IN CELL BIOLOGY
    70. Wang, Q; Zhang, HT; Fishel, R; Greene, MI
      BRCA1 and cell signaling

      ONCOGENE
    71. Zheng, L; Li, S; Boyer, TG; Lee, WH
      Lessons learned from BRCA1 and BRCA2

      ONCOGENE
    72. Ababou, M; Dutertre, S; Lecluse, Y; Onclercq, R; Chatton, B; Amor-Gueret, M
      ATM-dependent phosphorylation and accumulation of endogenous BLM protein in response to ionizing radiation

      ONCOGENE
    73. Liu, JS; Prolla, G; Rostagno, A; Chiarle, R; Feiner, H; Inghirami, G
      Initiation of translation from a downstream in-frame AUG codon on BRCA1 can generate the novel isoform protein Delta BRCA1(17aa)

      ONCOGENE
    74. Shall, S; de Murcia, G
      Poly(ADP-ribose) polymerase-1: what have we learned from the deficient mouse model?

      MUTATION RESEARCH-DNA REPAIR
    75. Bennett, LM; McAllister, KA; Blackshear, PE; Malphurs, J; Goulding, G; Collins, NK; Ward, T; Bunch, DO; Eddy, EM; Davis, BJ; Wiseman, RW
      Brca2-null embryonic survival is prolonged on the BALB/c genetic background

      MOLECULAR CARCINOGENESIS
    76. Tibbetts, RS; Cortez, D; Brumbaugh, KM; Scully, R; Livingston, D; Elledge, SJ; Abraham, RT
      Functional interactions between BRCA1 and the checkpoint kinase ATR duringgenotoxic stress

      GENES & DEVELOPMENT
    77. Roti, JLR; Gius, D; VanderWaal, RP; Xu, M
      Changes in sub-nuclear structures and functional perturbations: Implications for radiotherapy

      JOURNAL OF CELLULAR BIOCHEMISTRY
    78. Tauchi, H
      Positional cloning and functional analysis of the gene responsible for nijmegen breakage syndrome, NBS1

      JOURNAL OF RADIATION RESEARCH
    79. Piette, J; Munoz, P
      Implication of the G(2) checkpoint in the maintenance of genome integrity

      PATHOLOGIE BIOLOGIE
    80. Lanson, NA; Egeland, DB; Royals, BA; Claycomb, WC
      The MRE11-NBS1-RAD50 pathway is perturbed in SV40 large T antigen-immortalized AT-1, AT-2 and HL-1 cardiomyocytes

      NUCLEIC ACIDS RESEARCH
    81. Arizti, P; Fang, L; Park, I; Yin, YX; Solomon, E; Ouchi, T; Aaronson, SA; Lee, SW
      Tumor suppressor p53 is required to modulate BRCA1 expression

      MOLECULAR AND CELLULAR BIOLOGY
    82. Deng, CX; Brodie, SG
      Roles of BRCA1 and its interacting proteins

      BIOESSAYS
    83. Hama, S; Matsuura, S; Tauchi, H; Sawada, J; Kato, C; Yamasaki, F; Yoshioka, H; Sugiyama, K; Arita, K; Kurisu, K; Kamada, N; Heike, Y; Komatsu, K
      Absence of mutations in the NBS1 gene in B-cell malignant lymphoma patients

      ANTICANCER RESEARCH
    84. Hofmann, W; Schlag, PM
      BRCA1 and BRCA2 - breast cancer susceptibility genes

      JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
    85. Yeo, TC; Xia, D; Hassouneh, S; Yang, XO; Sabath, DE; Sperling, K; Gatti, RA; Concannon, P; Willerford, DM
      V(D)J rearrangement in Nijmegen breakage syndrome

      MOLECULAR IMMUNOLOGY
    86. De Lange, T; Petrini, JHJ
      A new connection at human telomeres: Association of the Mrell complex withTRF2

      COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY
    87. West, SC; Chapell, C; Hanakahi, LA; Masson, JY; McIlwraith, MJ; Van Dyck, E
      Double-strand break repair in human cells

      COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY
    88. Petrini, JHJ
      S-phase functions of the Mre11 complex

      COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY
    89. Kastan, MB; Lim, DS; Kim, ST; Xu, B; Canman, C
      Multiple signaling pathways involving ATM

      COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY
    90. Shiloh, Y
      ATM: Sounding the double-strand break alarm

      COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY
    91. Wu, X; Rathbun, G; Lane, WS; Weaver, DT; Livingston, DM
      Interactions of the Nijmegen breakage syndrome protein with ATM and BRCA1

      COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY
    92. Leadon, SA
      Transcription-coupled repair: A multifunctional signaling pathway

      COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY
    93. Venkitaraman, AR
      Chromosomal instability and cancer predisposition: Insights from studies on the breast cancer susceptibility gene, BRCA2

      COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY
    94. Zhao, S; Weng, YC; Yuan, SSF; Lin, YT; Hsu, HC; Lin, SCJ; Gerbino, E; Song, MH; Zdzienicka, MZ; Gatti, RA; Shay, JW; Ziv, Y; Shiloh, Y; Lee, EYHP
      Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products

      NATURE
    95. Limoli, CL; Giedzinski, E; Morgan, WF; Cleaver, JE
      Polymerase eta deficiency in the xeroderma pigmentosum variant uncovers anoverlap between the S phase checkpoint and double-strand break repair

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    96. McIlwraith, MJ; Van Dyck, E; Masson, JY; Stasiak, AZ; Stasiak, A; West, SC
      Reconstitution of the strand invasion step of double-strand break repair using human Rad51 Rad52 and RPA proteins

      JOURNAL OF MOLECULAR BIOLOGY
    97. Houvras, Y; Benezra, M; Zhang, HB; Manfredi, JJ; Weber, BL; Licht, JD
      BRCA1 physically and functionally interacts with ATF1

      JOURNAL OF BIOLOGICAL CHEMISTRY
    98. MacLachlan, TK; Dash, BC; Dicker, DT; El Deiry, WS
      Repression of BRCA1 through a feedback loop involving p53

      JOURNAL OF BIOLOGICAL CHEMISTRY
    99. Wu, GK; Lee, WH; Chen, PL
      NBS1 and TRF1 colocalize at promyelocytic leukemia bodies during late S/G(2) phases in immortalized telomerase-negative cells - Implication of NBS1 in alternative lengthening of telomeres

      JOURNAL OF BIOLOGICAL CHEMISTRY
    100. Girard, PM; Foray, N; Stumm, M; Waugh, A; Riballo, E; Maser, RS; Phillips, WP; Petrini, J; Arlett, CF; Jeggo, PA
      Radiosensitivity in Nijmegen Breakage syndrome cells is attributable to a repair defect and not cell cycle checkpoint defects

      CANCER RESEARCH


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Documento generato il 05/06/20 alle ore 12:37:51