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La ricerca find articoli where soggetti phrase all words 'DEPENDENT EXPRESSION' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 297 riferimenti
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    1. Fussenegger, M
      The impact of mammalian gene regulation concepts on functional genomic research, metabolic engineering, and advanced gene therapies

      BIOTECHNOLOGY PROGRESS
    2. Dugas, TR; Santa Cruz, V; Liu, HL; Kanz, MF
      Evaluation of the gender differences in 4,4 '-methylenedianiline toxicity,distribution, and effects on biliary parameters

      JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A
    3. Parks, LG; Lambright, CS; Orlando, EF; Guillette, LJ; Ankley, GT; Gray, LE
      Masculinization of female mosquitofish in kraft mill effluent-contaminatedFenholloway River water is associated with androgen receptor agonist activity

      TOXICOLOGICAL SCIENCES
    4. Matsuo, N; Shimoda, T; Mitsuta, K; Fukushima, C; Matsuse, H; Obase, Y; Kohno, S
      Tacrolimus inhibits cytokine production and chemical mediator release following antigen stimulation of passively sensitized human lung tissues

      ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY
    5. Savka, MA; Black, RC; Binns, AN
      Tobacco etch virus leader sequence enhances inducible indoleacetic acid-lysine synthetase activity in transgenic plants

      PLANT PHYSIOLOGY AND BIOCHEMISTRY
    6. Glaum, MC; Wang, Y; Raible, DG; Schulman, ES
      Degranulation influences heparin-associated inhibition of RT-PCR in human lung mast cells

      CLINICAL AND EXPERIMENTAL ALLERGY
    7. Benaud, CM; Dickson, RB
      Adhesion-regulated G1 cell cycle arrest in epithelial cells requires the downregulation of c-Myc

      ONCOGENE
    8. Bamba, M; Sugihara, H; Kushima, R; Okada, K; Tsukashita, S; Horinouchi, M; Hattori, T
      Time-dependent expression of intestinal phenotype in signet ring cell carcinomas of the human stomach

      VIRCHOWS ARCHIV-AN INTERNATIONAL JOURNAL OF PATHOLOGY
    9. Morito, K; Hirose, T; Kinjo, J; Hirakawa, T; Okawa, M; Nohara, T; Ogawa, S; Inoue, S; Muramatsu, M; Masamune, Y
      Interaction of phytoestrogens with estrogen receptors alpha and beta

      BIOLOGICAL & PHARMACEUTICAL BULLETIN
    10. Wu, W; Kocarek, TA; Runge-Morris, M
      Sex-dependent regulation by dexamethasone of murine hydroxysteroid sulfotransferase gene expression

      TOXICOLOGY LETTERS
    11. Oshima, T; Pavlick, KP; Laroux, FS; Verma, SK; Jordan, P; Grisham, MB; Williams, L; Alexander, JS
      Regulation and distribution of MAdCAM-1 in endothelial cells in vitro

      AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
    12. Kimura, M; Okano, Y
      Identification and assignment of the human NIMA-related protein kinase 7 gene (NEK7) to human chromosome 1q31.3

      CYTOGENETICS AND CELL GENETICS
    13. Bottazzi, ME; Buzzai, M; Zhu, XY; Desdouets, C; Brechot, C; Assoian, RK
      Distinct effects of mitogens and the actin cytoskeleton on CREB and pocketprotein phosphorylation control the extent and timing of cyclin A promoteractivity

      MOLECULAR AND CELLULAR BIOLOGY
    14. Brosenitsch, TA; Katz, DM
      Physiological patterns of electrical stimulation can induce neuronal gene expression by activating N-type calcium channels

      JOURNAL OF NEUROSCIENCE
    15. Russo, G; Lelli, A; Marcotti, W; Prigioni, I
      Gradients of expression of calcium and potassium currents in frog crista ampullaris

      PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
    16. Jenkins, GI; Long, JC; Wade, HK; Shenton, MR; Bibikova, TN
      UV and blue light signalling: pathways regulating chalcone synthase gene expression in Arabidopsis

      NEW PHYTOLOGIST
    17. Nehls, U; Bock, A; Ecke, M; Hampp, R
      Differential expression of the hexose-regulated fungal genes AmPAL and AmMst1 within Amanita/Populus ectomycorrhizas

      NEW PHYTOLOGIST
    18. Kawasaki, A; Matsumura, I; Miyagawa, J; Ezoe, S; Tanaka, H; Terada, Y; Tatsuka, M; Machii, T; Miyazaki, H; Furukawa, Y; Kanakura, Y
      Downregulation of an AIM-1 kinase couples with megakaryocytic polyploidization of human hematopoietic cells

      JOURNAL OF CELL BIOLOGY
    19. Yamada, A; Yamada, M; Fujita, Y; Nishigami, T; Nakasho, K; Uematsu, K
      Self-augmentation effect of male-specific products on sexually differentiated progesterone metabolism in adult male rat liver microsomes

      JOURNAL OF BIOLOGICAL CHEMISTRY
    20. Van Huffel, S; Delaei, F; Heyninck, K; De Valck, D; Beyaert, R
      Identification of a novel A20-binding inhibitor of nuclear factor-kappa B activation termed ABIN-2

      JOURNAL OF BIOLOGICAL CHEMISTRY
    21. Tang, CJC; Chuang, CK; Hu, HM; Tang, TK
      The zinc finger domain of Tzfp binds to the tbs motif located at the upstream flanking region of the Aie1 (aurora-C) kinase gene

      JOURNAL OF BIOLOGICAL CHEMISTRY
    22. Cafferata, EGA; Guerrico, AMG; Pivetta, OH; Santa-Coloma, TA
      NF-kappa B activation is involved in regulation of cystic fibrosis transmembrane conductance regulator (CFTR) by interleukin-1 beta

      JOURNAL OF BIOLOGICAL CHEMISTRY
    23. Korner, K; Jerome, V; Schmidt, T; Muller, R
      Cell cycle regulation of the murine cdc25B promoter - Essential role for nuclear factor-Y and a proximal repressor element

      JOURNAL OF BIOLOGICAL CHEMISTRY
    24. Phadtare, S; Inouye, M
      Role of CspC and CspE in regulation of expression of RpoS and UspA, the stress response proteins in Escherichia coli

      JOURNAL OF BACTERIOLOGY
    25. Nally, JE; Timoney, JF; Stevenson, B
      Temperature-regulated protein synthesis by Leptospira interrogans

      INFECTION AND IMMUNITY
    26. Klinkenberg, M; Van Huffel, S; Heyninck, K; Beyaert, R
      Functional redundancy of the zinc fingers of A20 for inhibition of NF-kappa B activation and protein-protein interactions

      FEBS LETTERS
    27. Xu, ZM; Kawai, M; Bandiera, SM; Chang, TKH
      Influence of dietary zinc deficiency during development on hepatic CYP2C11, CYP2C12, CYP3A2, CYP3A9, and CYP3A18 expression in postpubertal male rats

      BIOCHEMICAL PHARMACOLOGY
    28. Granet, C; Boutahar, N; Vico, L; Alexandre, C; Lafage-Proust, MH
      MAPK and SRC-kinases control EGR-1 and NF-kappa B inductions by changes inmechanical environment in osteoblasts

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    29. Iida, R; Yasuda, T; Tsubota, E; Matsuki, T; Kishi, K
      Cloning, mapping, genomic organization, and expression of mouse M-LP, a new member of the peroxisomal membrane protein Mpv17 domain family

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    30. Fidler, IJ
      Angiogenic heterogeneity: Regulation of neoplastic angiogenesis by the organ microenvironment

      JOURNAL OF THE NATIONAL CANCER INSTITUTE
    31. Fidler, IJ; Singh, RK; Yoneda, J; Kumar, R; Xu, L; Dong, ZY; Bielenberg, DR; McCarty, M; Ellis, LM
      Critical determinants of neoplastic angiogenesis

      CANCER JOURNAL
    32. Campbell, S; Larsen, J; Seif, MW; Allen, TD; Knox, F; Jones, CJP; Aplin, JD
      Mosaic characteristics of human endometrial epithelium in vitro: analysis of secretory markers and cell surface ultrastructure

      MOLECULAR HUMAN REPRODUCTION
    33. Wolosin, JM; Xiong, XL; Schutte, M; Stegman, Z; Tieng, A
      Stem cells and differentiation stages in the limbo-corneal epithelium

      PROGRESS IN RETINAL AND EYE RESEARCH
    34. Kelly, RG; Buckingham, ME
      Modular regulation of the MLC1F/3F gene and striated muscle diversity

      MICROSCOPY RESEARCH AND TECHNIQUE
    35. Weis, J; Kaussen, M; Calvo, S; Buonanno, A
      Denervation induces a rapid nuclear accumulation of MRF4 in mature myofibers

      DEVELOPMENTAL DYNAMICS
    36. Hein, DW; Doll, MA; Fretland, AJ; Leff, MA; Webb, SJ; Xiao, GH; Devanoboyina, US; Nangju, NA; Feng, Y
      Molecular genetics and epidemiology of the NAT1 and NAT2 acetylation polymorphisms

      CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
    37. Hu, HM; Chuang, CK; Lee, MJ; Tseng, TC; Tang, TK
      Genomic organization, expression, and chromosome localization of a third aurora-related kinase gene, Aie1

      DNA AND CELL BIOLOGY
    38. Urbanowski, ML; Stauffer, LT; Stauffer, GV
      The gcvB gene encodes a small untranslated RNA involved in expression of the dipeptide and oligopeptide transport systems in Escherichia coli

      MOLECULAR MICROBIOLOGY
    39. Tkatchenko, AV; Le Cam, G; Leger, JJ; Dechesne, CA
      Large-scale analysis of differential gene expression in the hindlimb muscles and diaphragm of mdx mouse

      BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
    40. Bouziane, M; Miao, F; Bates, SE; Somsouk, L; Sang, BC; Denissenko, M; O'Connor, TR
      Promoter structure and cell cycle dependent expression of the human methylpurine-DNA glycosylase gene

      MUTATION RESEARCH-DNA REPAIR
    41. Takahashi, T; Futamura, M; Yoshimi, N; Sano, J; Katada, M; Takagi, Y; Kimura, M; Yoshioka, T; Okano, Y; Saji, S
      Centrosomal kinases, HsAIRK1 and HsAIRK3, are overexpressed in primary colorectal cancers

      JAPANESE JOURNAL OF CANCER RESEARCH
    42. Skaanild, MT; Friis, C
      Expression changes of CYP2A and CYP3A in microsomes from pig liver and cultured hepatocytes

      PHARMACOLOGY & TOXICOLOGY
    43. Politopoulou, G; Seebach, JD; Schmugge, M; Schwarz, HP; Aguzzi, A
      Age-related expression of the cellular prion protein in human peripheral blood leukocytes

      HAEMATOLOGICA
    44. Ohshima, T
      Forensic wound examination

      FORENSIC SCIENCE INTERNATIONAL
    45. Boyle, SP; Craft, JA
      The effect of gender, sexual maturation and xenobiotic treatment on the formation of hydroxymethyl metabolites from 7,12-dimethylbenz[a]anthracene inrat liver microsomes

      TOXICOLOGY LETTERS
    46. Cabrera-Hernandez, A; Setlow, P
      Analysis of the regulation and function of five genes encoding small, acid-soluble spore proteins of Bacillus subtilis

      GENE
    47. Pedersen, LB; Ragkousi, K; Cammett, TJ; Melly, E; Sekowska, A; Schopick, E; Murray, T; Setlow, P
      Characterization of ywhE, which encodes a putative high-molecular-weight class A penicillin-binding protein in Bacillus subtilis

      GENE
    48. Solomon, PS; Shaw, AL; Young, MD; Leimkuhler, S; Hanson, GR; Klipp, W; McEwan, AG
      Molybdate-dependent expression of dimethylsulfoxide reductase in Rhodobacter capsulatus

      FEMS MICROBIOLOGY LETTERS
    49. Hagemeyer, CE; Rosenbrock, H; Singec, I; Knoth, R; Volk, B
      Different testosterone metabolism by immortalized embryonic and postnatal hippocampal neurons from C57BL/6 mice: A crucial role for androstenedione

      JOURNAL OF NEUROSCIENCE RESEARCH
    50. Sindhu, RK; Sakai, H; Kikkawa, Y
      Effect of hyperoxia on rat pulmonary and hepatic cytochrome P450 monooxygenases

      ARCHIVES OF TOXICOLOGY
    51. Wang, HM; Napoli, KL; Strobel, HW
      Cytochrome P450 3A9 catalyzes the metabolism of progesterone and other steroid hormones

      MOLECULAR AND CELLULAR BIOCHEMISTRY
    52. Ren, YS; Behre, E; Ren, ZJ; Zhang, JC; Wang, QB; Fondell, JD
      Specific structural motifs determine TRAP220 interactions with nuclear hormone receptors

      MOLECULAR AND CELLULAR BIOLOGY
    53. Seo, JW; Song, KB; Jang, KH; Kim, CH; Jung, BH; Rhee, SK
      Molecular cloning of a gene encoding the thermoactive levansucrase from Rahnella aquatilis and its growth phase-dependent expression in Escherichia coli

      JOURNAL OF BIOTECHNOLOGY
    54. Jung, YD; Ahmad, SA; Akagi, Y; Takahashi, Y; Liu, W; Reinmuth, N; Shaheen, RM; Fan, F; Ellis, LM
      Role of the tumor microenvironment in mediating response to anti-angiogenic therapy

      CANCER AND METASTASIS REVIEWS
    55. Mackay, S
      Gonadal development in mammals at the cellular and molecular levels

      INTERNATIONAL REVIEW OF CYTOLOGY - A SURVEY OF CELL BIOLOGY, VOL 200
    56. Graf, R; Brusis, N; Daunderer, C; Euteneuer, U; Hestermann, A; Schliwa, M; Ueda, M
      Comparative structural, molecular, and functional aspects of the Dictyostelium discoideum centrosome

      CENTROSOME IN CELL REPLICATION AND EARLY DEVELOPMENT
    57. Fry, AM; Mayor, T; Nigg, EA
      Regulating centrosomes by protein phosphorylation

      CENTROSOME IN CELL REPLICATION AND EARLY DEVELOPMENT
    58. Goepfert, TM; Brinkley, BR
      The centrosome-associated aurora/Ipl-like kinase family

      CENTROSOME IN CELL REPLICATION AND EARLY DEVELOPMENT
    59. Rothwell, WF; Sullivan, W
      The centrosome in early Drosophila embryogenesis

      CENTROSOME IN CELL REPLICATION AND EARLY DEVELOPMENT
    60. Swanson, MS; Hammer, BK
      Legionella pneumophila pathogenesis: A fateful journey from amoebae to macrophages

      ANNUAL REVIEW OF MICROBIOLOGY
    61. Low, D; Brandle, K; Nover, L; Forreiter, C
      Cytosolic heat-stress proteins Hsp17.7 class I and Hsp17.3 class II of tomato act as molecular chaperones in vivo

      PLANTA
    62. Lahiri, SD; Allison, LA
      Complementary expression of two plastid-localized alpha-like factors in maize

      PLANT PHYSIOLOGY
    63. Shoji, T; Yamada, Y; Hashimoto, T
      Jasmonate induction of putrescine N-methyltransferase genes in the root ofNicotiana sylvestris

      PLANT AND CELL PHYSIOLOGY
    64. Heuner, K; Dietrich, C; Steinert, M; Gobel, UB; Hacker, J
      Cloning and characterization of a Legionella pneumophila-specific gene encoding a member of the LysR family of transcriptional regulators

      MOLECULAR AND GENERAL GENETICS
    65. Masetto, S; Perin, P; Malusa, A; Zucca, G; Valli, P
      Membrane properties of chick semicircular canal hair cells in situ during embryonic development

      JOURNAL OF NEUROPHYSIOLOGY
    66. Coecke, S; Vanhaecke, T; Foriers, A; Phillips, IR; Vercruysse, A; Shephard, EA; Rogiers, V
      Hormonal regulation of glutathione S-transferase expression in co-culturedadult rat hepatocytes

      JOURNAL OF ENDOCRINOLOGY
    67. Liu, SH; Spinner, DS; Schmidt, MM; Danielsson, JA; Wang, SW; Schmidt, J
      Interaction of MyoD family proteins with enhancers of acetylcholine receptor subunit genes in vivo

      JOURNAL OF BIOLOGICAL CHEMISTRY
    68. Simpson, KJ; Ranganathan, S; Fisher, JA; Janssens, PA; Shaw, DC; Nicholas, KR
      The gene for a novel member of the whey acidic protein family encodes three four-disulfide core domains and is asynchronously expressed during lactation

      JOURNAL OF BIOLOGICAL CHEMISTRY
    69. West, JT; Estacio, W; Marquez-Magana, L
      Relative roles of the fla/che P-A, PD-3, and P-sigD promoters in regulating motility and sigD expression in Bacillus subtilis

      JOURNAL OF BACTERIOLOGY
    70. Machell, NH; Blaschuk, OW; Farookhi, R
      Developmental expression and distribution of N- and E-cadherin in the rat ovary

      BIOLOGY OF REPRODUCTION
    71. Kawai, M; Bandiera, SM; Chang, TKH; Bellward, GD
      Growth hormone regulation and developmental expression of rat hepatic CYP3A18, CYP3A9, and CYP3A2

      BIOCHEMICAL PHARMACOLOGY
    72. Bowie, A; O'Neill, LAJ
      Oxidative stress and nuclear factor-kappa B activation - A reassessment ofthe evidence in the light of recent discoveries

      BIOCHEMICAL PHARMACOLOGY
    73. Valdez, F; Gonzalez-Ceron, G; Kieser, HM; Servin-Gonzalez, L
      The Streptomyces coelicolor A3(2) lipAR operon encodes an extracellular lipase and a new type of transcriptional regulator

      MICROBIOLOGY-UK
    74. GOPALAN G; CENTANNI J; GILBERT DJ; COPELAND NG; JENKINS NA; DONOVAN PJ
      NOVEL MAMMALIAN KINASE RELATED TO YEAST AND FLY CHROMOSOME SEGREGATION REGULATORS IS EXCLUSIVELY EXPRESSED IN THE GERMLINE

      Molecular reproduction and development
    75. Zhang, Q; Dai, FY; Zhang, M; Hu, PR; Fu, Q; Fan, YX; Yu, L; Zhao, SY
      Molecular cloning and expression analysis of a novel human cDNA fragment encoding a putative Ser Thr protein kinase

      CHINESE SCIENCE BULLETIN
    76. Glatz, A; Vass, I; Los, DA; Vigh, L
      The Synechocystis model of stress: From molecular chaperones to membranes

      PLANT PHYSIOLOGY AND BIOCHEMISTRY
    77. Bischoff, JR; Plowman, GD
      The Aurora/Ipi1p kinase family: regulators of chromosome segregation and cytokinesis

      TRENDS IN CELL BIOLOGY
    78. Stoger, E; Williams, S; Keen, D; Christou, P
      Constitutive versus seed specific expression in transgenic wheat: temporaland spatial control

      TRANSGENIC RESEARCH
    79. Wang, SL; Nakashima, S; Nozawa, Y
      Stress-responsive changes in the mRNA levels of MAPK-related protein kinase (TpMAPK) and NIMA-related protein kinase (TpNrk) in Tetrahymena cells

      EUROPEAN JOURNAL OF PROTISTOLOGY
    80. Woollard, A; Hodgkin, J
      Stu-71air-2 is a C-elegans aurora homologue essential for chromosome segregation during embryonic and post-embryonic development

      MECHANISMS OF DEVELOPMENT
    81. Kelly, PA; Wang, H; Napoli, KL; Kahan, BD; Strobel, HW
      Metabolism of cyclosporine by cytochromes P450 3A9 and 3A4

      EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS
    82. Tani, Y; Yamamoto, H; Kawaji, A; Mizuno, H; Fukushige, J; Hosokawa, T; Doi, K
      Hepatic cytochrome P450 and flavin-containing monooxygenase in male Nts : Mini rat, a transgenic rat carrying antisense RNA transgene for rat growth hormone

      TOXICOLOGY LETTERS
    83. Chen, A; Yanai, A; Arama, E; Kilfin, G; Motro, B
      NIMA-related kinases: isolation and characterization of murine nek3 and nek4 cDNAs, and chromosomal localization of nek1, nek2 and nek3

      GENE
    84. Cabrera-Hernandez, A; Sanchez-Salas, JL; Paidhungat, M; Setlow, P
      Regulation of four genes encoding small, acid-soluble spore proteins in Bacillus subtilis

      GENE
    85. Fidler, IJ
      Critical determinants of cancer metastasis: rationale for therapy

      CANCER CHEMOTHERAPY AND PHARMACOLOGY
    86. Villarroya, F; Giralt, M; Iglesias, R
      Retinoids and adipose tissues: metabolism, cell differentiation and gene expression

      INTERNATIONAL JOURNAL OF OBESITY
    87. Verhoeven, G; Swinnen, JV
      Indirect mechanisms and cascades of androgen action

      MOLECULAR AND CELLULAR ENDOCRINOLOGY
    88. Zhang, LW; Pagano, JS
      Interferon regulatory factor 2 represses the Epstein-Barr virus BamHI Q latency promoter in type III latency

      MOLECULAR AND CELLULAR BIOLOGY
    89. Aplin, JD
      MUC-1 glycosylation in endometrium: possible roles of the apical glycocalyx at implantation

      HUMAN REPRODUCTION
    90. Diogon, T; Capelli, N; Greppin, H; Simon, P
      Isolation and characterization of a cDNA encoding a small subunit precursor of Rubisco in Spinacia oleracea

      ARCHIVES DES SCIENCES
    91. Peissner, W; Kocher, M; Treuer, H; Gillardon, F
      Ionizing radiation-induced apoptosis of proliferating stem cells in the dentate gyrus of the adult rat hippocampus

      MOLECULAR BRAIN RESEARCH
    92. Rey, D; Cuany, A; Pautou, MP; Meyran, JC
      Differential sensitivity of mosquito taxa to vegetable tannins

      JOURNAL OF CHEMICAL ECOLOGY
    93. Chow, T; Imaoka, S; Hiroi, T; Funae, Y
      Developmental changes in the catalytic activity and expression of CYP2D isoforms in the rat liver

      DRUG METABOLISM AND DISPOSITION
    94. Takahashi, J; Furuhata, Y; Ikeda, A; Takahashi, M; Iwata, H; Kazusaka, A; Fujita, S
      Characterization of hepatic cytochrome P450 isozyme composition in the transgenic rat expressing low level human growth hormone

      XENOBIOTICA
    95. Keppler, OT; Hinderlich, S; Langner, J; Schwartz-Albiez, R; Reutter, W; Pawlita, M
      UDP-GlcNAc 2-epimerase: A regulator of cell surface sialylation

      SCIENCE
    96. Short, TW
      Overexpression of Arabidopsis phytochrome B inhibits phytochrome A function in the presence of sucrose

      PLANT PHYSIOLOGY
    97. Fiebich, BL; Hofer, TJ; Lieb, K; Huell, M; Butcher, RD; Schumann, G; Schulze-Osthoff, K; Bauer, J
      The non-steroidal anti-inflammatory drug tepoxalin inhibits interleukin-6 and alpha(1)-anti-chymotrypsin synthesis in astrocytes by preventing degradation of I kappa B-alpha

      NEUROPHARMACOLOGY
    98. Sueyoshi, T; Yokomori, N; Korach, KS; Negishi, M
      Developmental action of estrogen receptor-alpha feminizes the growth hormone-Stat5b pathway and expression of Cyp2a4 and Cyp2d9 genes in mouse liver

      MOLECULAR PHARMACOLOGY
    99. Shieh, PB; Ghosh, A
      Molecular mechanisms underlying activity-dependent regulation of BDNF expression

      JOURNAL OF NEUROBIOLOGY
    100. Schenk, S; Decker, K
      Horizontal gene transfer involved in the convergent evolution of the plasmid-encoded enantioselective 6-hydroxynicotine oxidases

      JOURNAL OF MOLECULAR EVOLUTION


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Documento generato il 28/10/20 alle ore 22:23:29