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La ricerca find articoli where soggetti phrase all words 'DELAYED RECTIFIER K+' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 89 riferimenti
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    1. Yeon, D; Kwon, S; Lee, Y; Leem, J; Nam, T; Ahn, D
      Capsaicin-induced relaxation in rabbit coronary artery

      JOURNAL OF VETERINARY MEDICAL SCIENCE
    2. Yeon, D; Kwon, S; Nam, T; Ahn, D
      Lysophosphatidylcholine decreases delayed rectifier K+ current in rabbit coronary smooth muscle cells

      JOURNAL OF VETERINARY MEDICAL SCIENCE
    3. Van Goor, F; Li, YX; Stojilkovic, SS
      Paradoxical role of large-conductance calcium-activated K+ (BK) channels in controlling action potential-driven Ca2+ entry in anterior pituitary cells

      JOURNAL OF NEUROSCIENCE
    4. Toth, TI; Crunelli, V
      Estimation of the activation and kinetic properties of I-Na and I-K from the time course of the action potential

      JOURNAL OF NEUROSCIENCE METHODS
    5. Ohyama, H; Kajita, H; Omori, K; Takumi, T; Hiramoto, N; Iwasaka, T; Matsuda, H
      Inhibition of cardiac delayed rectifier K+ currents by an antisense oligodeoxynucleotide against IsK (minK) and over-expression of IsK mutant D77N inneonatal mouse hearts

      PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
    6. Wu, SN; Lo, YK; Chen, HY; Li, HF; Chiang, HT
      Rutaecarpine-induced block of delayed rectifier K+ current in NG108-15 neuronal cells

      NEUROPHARMACOLOGY
    7. Perchenet, L; Clement-Chomienne, O
      External nickel blocks human Kv1.5 channels stably expressed in CHO cells

      JOURNAL OF MEMBRANE BIOLOGY
    8. Lu, Y; Zhang, J; Tang, G; Wang, R
      Modulation of voltage-dependent K+ channel current in vascular smooth muscle cells from rat mesenteric arteries

      JOURNAL OF MEMBRANE BIOLOGY
    9. Kocic, I; Hirano, Y; Hiraoka, M
      Ionic basis for membrane potential changes induced by hypoosmotic stress in guinea-pig ventricular myocytes

      CARDIOVASCULAR RESEARCH
    10. Zhang, Y; Paterson, WG
      Diversity of K+ channels in circular smooth muscle of opossum lower esophageal sphincter

      CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
    11. Schaffer, S; Takahashi, K; Azuma, J
      Role of osmoregulation in the actions of taurine

      AMINO ACIDS
    12. Ha, M; Kwon, S; Lee, YH; Yeon, D; Ahn, DS
      Sulfhydryl modification affects coronary artery tension by changing activity of delayed rectifier K+ current

      YONSEI MEDICAL JOURNAL
    13. Schilling, T; Quandt, FN; Cherny, VV; Zhou, W; Heinemann, U; Decoursey, TE; Eder, C
      Upregulation of Kv1.3 K+ channels in microglia deactivated by TGF-beta

      AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
    14. Witchel, HJ; Hancox, JC
      Familial and acquired long QT syndrome and the cardiac rapid delayed rectifier potassium current

      CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
    15. Sato, N; Tanaka, H; Habuchi, Y; Giles, WR
      Electrophysiological effects of ibutilide on the delayed rectifier K+ current in rabbit sinoatrial and atrioventricular node cells

      EUROPEAN JOURNAL OF PHARMACOLOGY
    16. Jones, SE; Missan, S; Zhabyeyev, P; McDonald, TF
      Selective phenylalkylamine block of I-Kr over other K+ currents in guinea-pig ventricular myocytes

      BRITISH JOURNAL OF PHARMACOLOGY
    17. Nakaya, H; Furusawa, Y; Ogura, T; Tamagawa, M; Uemura, H
      Inhibitory effects of JTV-519, a novel cardioprotective drug, on potassiumcurrents and experimental atrial fibrillation in guinea-pig hearts

      BRITISH JOURNAL OF PHARMACOLOGY
    18. Jones, SE; Shuba, LM; Zhabyeyev, P; McCullough, JR; McDonald, TF
      Differences in the effects of urinary incontinence agents S-oxybutynin andterodiline on cardiac K+ currents and action potentials

      BRITISH JOURNAL OF PHARMACOLOGY
    19. Van den Bossche, I; Vanheel, B
      Influence of cannabinoids on the delayed rectifier in freshly dissociated smooth muscle cells of the rat aorta

      BRITISH JOURNAL OF PHARMACOLOGY
    20. Jo, SH; Youm, JB; Lee, CO; Earm, YE; Ho, WK
      Blockade of the HERG human cardiac K+ channel by the antidepressant drug amitriptyline

      BRITISH JOURNAL OF PHARMACOLOGY
    21. Ming, OY; Shao, W
      Dexamethasone attenuates the depressor response induced by neuropeptide Y microinjected into the nucleus tractus solitarius in rats

      BRITISH JOURNAL OF PHARMACOLOGY
    22. Fujisawa, S; Ono, K; Iijima, T
      Time-dependent block of the slowly activating delayed rectifier K+ currentby chromanol 293B in guinea-pig ventricular cells

      BRITISH JOURNAL OF PHARMACOLOGY
    23. Pannicke, T; Faude, F; Reichenbach, A; Reichelt, W
      A function of delayed rectifier potassium channels in glial cells: maintenance of an auxiliary membrane potential under pathological conditions

      BRAIN RESEARCH
    24. Carmeliet, E
      Cardiac ionic currents and acute ischemia: From channels to arrhythmias

      PHYSIOLOGICAL REVIEWS
    25. Song, DK; Earm, YE; Ho, WK
      Blockade of the delayed rectifier K+ currents, I-Kr, in rabbit sinoatrial node cells by external divalent cations

      PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
    26. Matsubayashi, T; Matsuura, H; Ehara, T
      On the mechanism of the enhancement of delayed rectifier K+ current by extracellular ATP in guinea-pig ventricular myocytes

      PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
    27. Wang, HZ; Shi, H; Wang, ZG
      Nicotine depresses the functions of multiple cardiac potassium channels

      LIFE SCIENCES
    28. Yu, SP; Yeh, CH; Gottron, F; Wang, X; Grabb, MC; Choi, DW
      Role of the outward delayed rectifier K+ current in ceramide-induced caspase activation and apoptosis in cultured cortical neurons

      JOURNAL OF NEUROCHEMISTRY
    29. Matsumoto, Y; Ogura, T; Uemura, H; Saito, T; Masuda, Y; Nakaya, H
      Histamine H-1-receptor-mediated modulation of the delayed rectifier K+ current in guinea-pig atrial cells: opposite effects on I-Ks and I-Kr

      BRITISH JOURNAL OF PHARMACOLOGY
    30. Dick, GM; Kong, ID; Sanders, KM
      Effects of anion channel antagonists in canine colonic myocytes: comparative pharmacology of Cl-, Ca2+ and K+ currents

      BRITISH JOURNAL OF PHARMACOLOGY
    31. Catacuzzeno, L; Trequattrini, C; Petris, A; Franciolini, F
      Mechanism of verapamil block of a neuronal delayed rectifier K channel: active form of the blocker and location of its binding domain

      BRITISH JOURNAL OF PHARMACOLOGY
    32. Sobey, CG; Faraci, FM
      Inhibitory effect of 4-aminopyridine on responses of the basilar artery tonitric oxide

      BRITISH JOURNAL OF PHARMACOLOGY
    33. Ohmoto-Sekine, Y; Uemura, H; Tamagawa, M; Nakaya, H
      Inhibitory effects of aprindine on the delayed rectifier K+ current and the muscarinic acetylcholine receptor-operated K+ current in guinea-pig atrial cells

      BRITISH JOURNAL OF PHARMACOLOGY
    34. Satoh, H
      Taurine modulates I-Kr but not I-Ks, in guinea-pig ventricular cardiomyocytes

      BRITISH JOURNAL OF PHARMACOLOGY
    35. Yamakage, M; Matsuzaki, T; Tsujiguchi, N; Honma, Y; Namiki, A
      Inhibitory effects of diazepam and midazolam on Ca2+ and K+ channels in canine tracheal smooth muscle cells

      ANESTHESIOLOGY
    36. CHUNG S; LEE MY; SOH H; JUNG W; JOE E
      MODULATION OF MEMBRANE-POTENTIAL BY EXTRACELLULAR PH IN ACTIVATED MICROGLIA IN RATS

      Neuroscience letters
    37. CHUNG S; JOE E; SOH H; LEE MY; BANG HW
      DELAYED RECTIFIER POTASSIUM CURRENTS INDUCED IN ACTIVATED RAT MICROGLIA SET THE RESTING MEMBRANE-POTENTIAL

      Neuroscience letters
    38. ZHU MY; GELBAND CH; MOORE JM; POSNER P; SUMNERS C
      ANGIOTENSIN-II TYPE-2 RECEPTOR STIMULATION OF NEURONAL DELAYED-RECTIFIER POTASSIUM CURRENT INVOLVES PHOSPHOLIPASE A(2) AND ARACHIDONIC-ACID

      The Journal of neuroscience
    39. LIU YM; YU H; LI CZ; COHEN IS; VASSALLE M
      CESIUM EFFECTS ON I(F) AND I(K) IN RABBIT SINOATRIAL NODE MYOCYTES - IMPLICATIONS FOR SA NODE AUTOMATICITY

      Journal of cardiovascular pharmacology
    40. TOHSE N; HOUZEN H; KANNO M
      INHIBITION OF THE DELAYED RECTIFIER K CURRENT IN GUINEA-PIG CARDIOMYOCYTES BY THIAMINE TETRAHYDROFURFURYL DISULFIDE

      Naunyn-Schmiedeberg's archives of pharmacology
    41. Washizuka, T; Horie, M; Obayashi, K; Sasayama, S
      Genistein inhibits slow component delayed-rectifier K currents via a tyrosine kinase-independent pathway

      JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
    42. HOOL LC; MIDDLETON LM; HARVEY RD
      GENISTEIN INCREASES THE SENSITIVITY OF CARDIAC ION CHANNELS TO BETA-ADRENERGIC-RECEPTOR STIMULATION

      Circulation research
    43. ETO K; HASHIMOTO K; NAKAYA H
      PREFERENTIAL INHIBITION OF I-KR BY MCI-154, A PUTATIVE CARDIOTONIC CA2-PIG ATRIAL CELLS( SENSITIZER, IN GUINEA)

      Cardiovascular Research
    44. OSIPENKO ON; ALEXANDER D; MACLEAN MR; GURNEY AM
      INFLUENCE OF CHRONIC HYPOXIA ON THE CONTRIBUTIONS OF NONINACTIVATING AND DELAYED RECTIFIER-K CURRENTS TO THE RESTING POTENTIAL AND TONE OF RAT PULMONARY-ARTERY SMOOTH-MUSCLE

      British Journal of Pharmacology
    45. SMIRNOV SV; KNOCK GA; AARONSON PI
      EFFECTS OF THE 5-LIPOXYGENASE ACTIVATING PROTEIN INHIBITOR MK886 ON VOLTAGE-GATED AND CA2-ACTIVATED K+ CURRENTS IN RAT ARTERIAL MYOCYTES()

      British Journal of Pharmacology
    46. CHARPENTIER F; MEROT J; RIOCHET D; LEMAREC H; ESCANDE D
      ADULT KCNE1-KNOCKOUT MICE EXHIBIT A MILD CARDIAC CELLULAR PHENOTYPE

      Biochemical and biophysical research communications (Print)
    47. SATOH H
      EFFECTS OF NICOTINE ON SPONTANEOUS ACTIVITY AND UNDERLYING IONIC CURRENTS IN RABBIT SINOATRIAL NODAL CELLS

      General pharmacology
    48. WEYERBROCK S; SCHREIECK J; KARCH M; OVERBECK M; MEISNER H; KEMKES B; SCHOMIG A; SCHMITT C
      RATE-INDEPENDENT EFFECTS OF THE NEW CLASS-III ANTIARRHYTHMIC AGENT AMBASILIDE ON TRANSMEMBRANE ACTION-POTENTIALS IN HUMAN VENTRICULAR ENDOMYOCARDIUM

      Journal of cardiovascular pharmacology
    49. HAYASHI S; NATSUKAWA T; SUMA C; UKAI Y; YOSHIKUNI Y; KIMURA K
      CARDIAC ELECTROPHYSIOLOGICAL ACTIONS OF NS-21 AND ITS ACTIVE METABOLITE, RCC-36, COMPARED WITH TERODILINE

      Naunyn-Schmiedeberg's archives of pharmacology
    50. BHATTACHARYYA ML; SARKER S; MULL KP; DEBNAM Q
      CLOFILIUM-INDUCED BLOCK OF DELAYED RECTIFIER TYPE K-CELLS (AT-1 CELLS)( CURRENT IN ATRIAL TUMOR)

      Journal of Molecular and Cellular Cardiology
    51. CLEMO HF; BAUMGARTEN CM
      SWELLING-ACTIVATED GD3-SENSITIVE CATION CURRENT AND CELL-VOLUME REGULATION IN RABBIT VENTRICULAR MYOCYTES()

      The Journal of general physiology
    52. LONDON B; TRUDEAU MC; NEWTON KP; BEYER AK; COPELAND NG; GILBERT DJ; JENKINS NA; SATLER CA; ROBERTSON GA
      2 ISOFORMS OF THE MOUSE ETHER-A-GO-GO-RELATED GENE COASSEMBLE TO FORMCHANNELS WITH PROPERTIES SIMILAR TO THE RAPIDLY ACTIVATING COMPONENT OF THE CARDIAC DELAYED RECTIFIER K+ CURRENT

      Circulation research
    53. WASHIZUKA T; HORIE M; WATANUKI M; SASAYAMA S
      ENDOTHELIN-1 INHIBITS THE SLOW COMPONENT OF CARDIAC DELAYED RECTIFIERK-TOXIN-SENSITIVE MECHANISM( CURRENTS VIA A PERTUSSIS)

      Circulation research
    54. WYMORE RS; GINTANT GA; WYMORE RT; DIXON JE; MCKINNON D; COHEN IS
      TISSUE AND SPECIES DISTRIBUTION OF MESSENGER-RNA FOR THE I-KR-LIKE K+CHANNEL, ERG

      Circulation research
    55. RAVENS U; HIMMEL HM; FLUSS M; DAVIA K; HARDING SE
      PHOSPHODIESTERASE INHIBITION AND CA2+ SENSITIZATION

      Molecular and cellular biochemistry
    56. GALLO V; ZHOU JM; MCBAIN CJ; WRIGHT P; KNUTSON PL; ARMSTRONG RC
      OLIGODENDROCYTE PROGENITOR-CELL PROLIFERATION AND LINEAGE PROGRESSIONARE REGULATED BY GLUTAMATE RECEPTOR-MEDIATED K+ CHANNEL BLOCK

      The Journal of neuroscience
    57. IMAMURA H; FURUKAWA Y; YAMAZAKI K; NAKANO H; KASAMA M; HOYANO Y; CHIBA S
      ATRIOVENTRICULAR JUNCTIONAL RHYTHM INDUCED BY SYMPATHETIC-STIMULATIONIN E-4031-TREATED DOG HEARTS

      Journal of cardiovascular pharmacology
    58. KOH SD; SANDERS KM; CARL A
      REGULATION OF SMOOTH-MUSCLE DELAYED RECTIFIER K-KINASE-A( CHANNELS BYPROTEIN)

      Pflugers Archiv
    59. HOWARTH FC; LEVI AJ; HANCOX JC
      CHARACTERISTICS OF THE DELAYED RECTIFIER K CURRENT COMPARED IN MYOCYTES ISOLATED FROM THE ATRIOVENTRICULAR NODE AND VENTRICLE OF THE RABBITHEART

      Pflugers Archiv
    60. WANG DW; KIYOSUE T; SATO T; ARITA M
      COMPARISON OF THE EFFECTS OF CLASS-I ANTIARRHYTHMIC DRUGS, CIBENZOLINE, MEXILETINE AND FLECAINIDE, ON THE DELAYED RECTIFIER K-PIG VENTRICULAR MYOCYTES( CURRENT OF GUINEA)

      Journal of Molecular and Cellular Cardiology
    61. ISHII Y; MURAKI K; KURIHARA A; IMAIZUMI Y; WATANABE M
      EFFECTS OF SEMATILIDE, A NOVEL CLASS-III ANTIARRHYTHMIC AGENT, ON DELAYED RECTIFIER K-PIG ATRIAL MYOCYTES( CURRENT IN GUINEA)

      Japanese Journal of Pharmacology
    62. NOMA A
      IONIC MECHANISMS OF THE CARDIAC-PACEMAKER POTENTIAL

      Japanese Heart Journal
    63. YAMAZAKI K; FURUKAWA Y; KASAMA M; IMAMURA H; CHIBA S
      NEGATIVE CHRONOTROPIC AND DROMOTROPIC EFFECTS OF E-4031, AN I-KR BLOCKER, ON THE ATRIOVENTRICULAR NODE IN ANESTHETIZED DOG HEARTS

      European journal of pharmacology
    64. VANDIER C; BONNET P
      SYNERGISTIC ACTION OF NS-004 AND INTERNAL CA2-ARTERY K+ CHANNELS( CONCENTRATION IN MODULATING PULMONARY)

      European journal of pharmacology
    65. WANG ZR; MITSUIYE T; NOMA A
      CELL DISTENSION-INDUCED INCREASE OF THE DELAYED RECTIFIER K-PIG VENTRICULAR MYOCYTES( CURRENT IN GUINEA)

      Circulation research
    66. GINTANT GA
      2 COMPONENTS OF DELAYED RECTIFIER CURRENT IN CANINE ATRIUM AND VENTRICLE - DOES I-KS PLAY A ROLE IN THE REVERSE RATE DEPENDENCE OF CLASS-III AGENTS

      Circulation research
    67. BOYETT MR; HARRISON SM; JANVIER NC; MCMORN SO; OWEN JM; SHUI Z
      A LIST OF VERTEBRATE CARDIAC IONIC CURRENTS - NOMENCLATURE, PROPERTIES, FUNCTION AND CLONED EQUIVALENTS

      Cardiovascular Research
    68. VANDENBERG JI; REES SA; WRIGHT AR; POWELL T
      CELL SWELLING AND ION-TRANSPORT PATHWAYS IN CARDIAC MYOCYTES

      Cardiovascular Research
    69. HOLLAND M; LANGTON PD; STANDEN NB; BOYLE JP
      EFFECTS OF THE BKCA CHANNEL ACTIVATOR, NS1619, ON RAT CEREBRAL-ARTERYSMOOTH-MUSCLE

      British Journal of Pharmacology
    70. SATOH H
      A DUAL-ACTION OF TAURINE ON THE DELAYED RECTIFIER K+ CURRENT IN EMBRYONIC CHICK CARDIOMYOCYTES

      Amino acids
    71. IIJIMA T; ABE T; FUJISAWA S
      VASOPRESSIN-1 RECEPTOR-MEDIATED INCREASE IN DELAYED RECTIFIER POTASSIUM CURRENT IN VENTRICULAR CELLS OF GUINEA-PIG HEARTS

      Heart and vessels
    72. KIYOSUE T; ARITA M
      RECONSTRUCTION OF ACTION-POTENTIALS IN DIALYZED GUINEA-PIG VENTRICULAR MYOCYTES

      Heart and vessels
    73. ONO K; ITO H
      THE ROLE OF THE DELAYED RECTIFIER K+ CURRENT IN THE PACEMAKER ACTIVITY IN RABBIT SINOATRIAL NODE CELLS

      Heart and vessels
    74. MING Z; NORDIN C
      TERFENADINE BLOCKS TIME-DEPENDENT CA2-PIG VENTRICULAR MYOCYTES(, NA+,AND K+ CHANNELS IN GUINEA)

      Journal of cardiovascular pharmacology
    75. VANLUNTEREN E; VAFAIE H; MOYER M
      CHANGES IN PHARYNGEAL RESPIRATORY MUSCLE FORCE PRODUCED BY K+ CHANNELBLOCKADE

      Respiration physiology
    76. TOHSE N; KANNO M
      EFFECTS OF DOFETILIDE ON MEMBRANE CURRENTS IN SINOATRIAL NODE CELLS OF RABBIT

      Japanese Journal of Pharmacology
    77. YANG T; KUPERSHMIDT S; RODEN DM
      ANTI-MINK ANTISENSE DECREASES THE AMPLITUDE OF THE RAPIDLY ACTIVATINGCARDIAC DELAYED RECTIFIER K+ CURRENT

      Circulation research
    78. DUFF HJ; FENG ZP; SHELDON RS
      HIGH- AND LOW-AFFINITY SITES FOR [H-3] DOFETILIDE BINDING TO GUINEA-PIG MYOCYTES

      Circulation research
    79. LIU DW; ANTZELEVITCH C
      CHARACTERISTICS OF THE DELAYED RECTIFIER CURRENT (I-KR AND I-KS) IN CANINE VENTRICULAR EPICARDIAL, MIDMYOCARDIAL, AND ENDOCARDIAL MYOCYTES - A WEAKER I-KS CONTRIBUTES TO THE LONGER ACTION-POTENTIAL OF THE M-CELL

      Circulation research
    80. CARRIER GO
      WHOLE-CELL AND PERFORATED-PATCH RECORDINGS OF 4 DISTINCT K-SUPERIOR MESENTERIC GANGLIA NEURONS OF ADULT-RATS( CURRENTS IN ACUTELY DISPERSEDCELIAC)

      Brain research
    81. CRUZ JD; MATSUDA H
      DEPRESSIVE EFFECTS OF ARENOBUFAGIN ON THE DELAYED RECTIFIER K-PIG CARDIAC MYOCYTES( CURRENT OF GUINEA)

      European journal of pharmacology. Molecular pharmacology section
    82. KOUMI S; SATO R; HAYAKAWA H
      MODULATION OF THE DELAYED RECTIFIER K-PIG HEART( CURRENT BY APAMIN INGUINEA)

      European journal of pharmacology
    83. SASAKI N; MITSUIYE T; WANG ZR; NOMA A
      INCREASE OF THE DELAYED RECTIFIER K-K+ PUMP CURRENTS BY HYPOTONIC SOLUTIONS IN GUINEA-PIG CARDIAC MYOCYTES( AND NA+)

      Circulation research
    84. NITTA J; FURUKAWA T; MARUMO F; SAWANOBORI T; HIRAOKA M
      SUBCELLULAR MECHANISM FOR CA2-DEPENDENT ENHANCEMENT OF DELAYED RECTIFIER K+ CURRENT IN ISOLATED MEMBRANE PATCHES OF GUINEA-PIG VENTRICULAR MYOCYTES()

      Circulation research
    85. ALBRECHT B; LORRA C; STOCKER M; PONGS O
      CLONING AND CHARACTERIZATION OF A HUMAN DELAYED RECTIFIER POTASSIUM CHANNEL GENE

      Receptors & channels
    86. FREEMAN LC; KASS RS
      DELAYED RECTIFIER POTASSIUM CHANNELS IN VENTRICLE AND SINOATRIAL NODEOF THE GUINEA-PIG - MOLECULAR AND REGULATORY PROPERTIES

      Cardiovascular drugs and therapy
    87. GELBAND CH; ISHIKAWA T; POST JM; KEEF KD; HUME JR
      INTRACELLULAR DIVALENT-CATIONS BLOCK SMOOTH-MUSCLE K+ CHANNELS

      Circulation research
    88. EDWARDS G; IBBOTSON T; WESTON AH
      LEVCROMAKALIM MAY INDUCE A VOLTAGE-INDEPENDENT K-CURRENT IN RAT PORTAL VEINS BY MODIFYING THE GATING PROPERTIES OF THE DELAYED RECTIFIER

      British Journal of Pharmacology
    89. NAKAYA H; TOHSE N; TAKEDA Y; KANNO M
      EFFECTS OF MS-551, A NEW CLASS-III ANTIARRHYTHMIC DRUG, ON ACTION-POTENTIAL AND MEMBRANE CURRENTS IN RABBIT VENTRICULAR MYOCYTES

      British Journal of Pharmacology


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Documento generato il 26/10/20 alle ore 03:35:37