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DNA methylation variation in cloned mice
GENESIS
Sequential 5-aza-2 '-deoxycytidine-depsipeptide FR901228 treatment inducesapoptosis preferentially in cancer cells and facilitates their recognitionby cytolytic T lymphocytes specific for NY-ESO-1
JOURNAL OF IMMUNOTHERAPY
Global methylation profiling of lung cancer identifies novel methylated genes
NEOPLASIA
Chromosomal DNA demethylation specified by protein binding
EMBO REPORTS
Heterogeneity of DNA methylation status analyzed by bisulfite-PCR-SSCP andcorrelation with clinico-pathological characteristics in colorectal cancer
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
Construction of 700 human/mouse A9 monochromosomal hybrids and analysis ofimprinted genes on human chromosome 6
JOURNAL OF HUMAN GENETICS
DNA methylation in breast cancer
ENDOCRINE-RELATED CANCER
Role of DNA methylation and histone acetylation in steroid receptor expression in breast cancer
JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA
5-azacytidine modulates the response of sensitive and multidrug-resistant K562 leukemic cells to cytostatic drugs
BLOOD CELLS MOLECULES AND DISEASES
Molecular detection of prostate cancer in urine by GSTP1 hypermethylation
CLINICAL CANCER RESEARCH
Promoter hypermethylation of multiple genes in carcinoma of the uterine cervix
CLINICAL CANCER RESEARCH
Aberrant methylation during cervical carcinogenesis
CLINICAL CANCER RESEARCH
A cell death-promoting kinase
NATURE STRUCTURAL BIOLOGY
A new PCR assay useful for screening of FRAXE/FMR2 mental impairment amongmales
HUMAN MUTATION
Methylation profiling of human cancers in blood: Molecular monitoring and prognostication (Review)
INTERNATIONAL JOURNAL OF ONCOLOGY
Heterogeneous methylation of the O-6-methylguanine-DNA methyltransferase promoter in immortalized IMR90 cell lines
INTERNATIONAL JOURNAL OF ONCOLOGY
Comprehensive methylation analysis in typical and atypical PWS and AS patients with normal biparental chromosomes 15
EUROPEAN JOURNAL OF HUMAN GENETICS
Tumor suppressor loss in pituitary tumors
BRAIN PATHOLOGY
The endothelin receptor B (EDNRB) promoter displays heterogeneous, site specific methylation patterns in normal and tumor cells
HUMAN MOLECULAR GENETICS
Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer
HUMAN MOLECULAR GENETICS
Distant cis-elements regulate imprinted expression of the mouse p57(KiP2) (Cdkn1C) gene: implications for the human disorder, Beckwith-Wiedemann syndrome
HUMAN MOLECULAR GENETICS
Molecular markers of tumor initiation and progression
CURRENT OPINION IN GENETICS & DEVELOPMENT
Quantitative real-time PCR does not show selective targeting of p14(ARF) but concomitant inactivation of both p16(INK4A) and p14(ARF) in 105 human primary gliomas
ONCOGENE
Increased expression of unmethylated CDKN2D by 5-aza-2 '-deoxycytidine in human lung cancer cells
ONCOGENE
A CREB site in the BRCA1 proximal promoter acts as a constitutive transcriptional element
ONCOGENE
Expression of p15 and p15.5 products in neuroendocrine lung tumours: relationship with p15(INK4b) methylation status
ONCOGENE
The CpG island of the novel tumor suppressor gene RASSF1A is intensely methylated in primary small cell lung carcinomas
ONCOGENE
DNA methylation, methyltransferases, and cancer
ONCOGENE
Promoter methylation of DAP-kinase: association with advanced stage in non-small cell lung cancer
ONCOGENE
Non-imprinted Igf2r expression decreases growth and rescues the Tme mutation in mice
DEVELOPMENT
Epigenetic silencing of PEG3 gene expression in human glioma cell lines
MOLECULAR CARCINOGENESIS
A view through the clouds of imprinting
FASEB JOURNAL
Lsh, a member of the SNF2 family, is required for genome-wide methylation
GENES & DEVELOPMENT
Bidirectional action of the Igf2r imprint control element on upstream and downstream imprinted genes
GENES & DEVELOPMENT
CpG island of rat sphingosine kinase-1 gene: tissue-dependent DNA methylation status and multiple alternative first exons
GENOMICS
The Prader-Willi syndrome imprinting center activates the paternally expressed murine Ube3a antisense transcript but represses paternal Ube3a
GENOMICS
ABL1 methylation in Ph-positive ALL is exclusively associated with the P210 form of BCR-ABL
LEUKEMIA
Expansion mutation frequency and CGG/GCC repeat polymorphism in FMR1 and FMR2 genes in an Indian population
GENETIC EPIDEMIOLOGY
Full-sized RanBPM cDNA encodes a protein possessing a long stretch of proline and glutamine within the N-terminal region, comprising a large protein complex
GENE
Transcriptional regulation of human oxysterol 7 alpha-hydroxylase gene (CYP7B1) by Sp1
GENE
Human-mouse comparative sequence analysis of the NEMO gene reveals an alternative promoter within the neighboring G6PD gene
GENE
Glucose 6-phosphate dehydrogenase expression is less prone to variegation when driven by its own promoter
GENE
The Haspin gene: location in an intron of the Integrin alpha E gene, associated transcription of an Integrin alpha E-derived RNA and expression in diploid as well as haploid cells
GENE
E-cadherin expression is commonly downregulated by CpG island hypermethylation in esophageal carcinoma cells
CANCER LETTERS
Inverse association between cyclooxygenase-2 overexpression and microsatellite instability in gastric cancer
CANCER LETTERS
Mutations, methylation and expression of CDKN2 alpha/p16 gene in colorectal cancer and normal colonic mucosa
CANCER LETTERS
Methylation of the p16(Ink4 alpha) tumor suppressor gene 5 '-CpG island inbreast cancer
CANCER LETTERS
Investigation of elements sufficient to imprint the mouse air promoter
MOLECULAR AND CELLULAR BIOLOGY
Protein binding protects sites on stable episomes and in the chromosome from de novo methylation
MOLECULAR AND CELLULAR BIOLOGY
Hypermethylation of the caveolin-1 gene promoter in prostate cancer
PROSTATE
The marks, mechanisms and memory of epigenetic states in mammals
BIOCHEMICAL JOURNAL
Glucocorticoid-induced DNA demethylation and gene memory during development
EMBO JOURNAL
CDKN2A/p16 in ependymomas
JOURNAL OF NEURO-ONCOLOGY
The INK4A/ARF locus: Role in cell cycle control and apoptosis and implications for glioma growth
JOURNAL OF NEURO-ONCOLOGY
Expression of AP-2 alpha in SV40 immortalized human lung fibroblasts is associated with a distinct pattern of cytosine methylation in the AP-2 alpha promoter
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION
Possible prediction of myeloid and lymphoid crises in chronic myelocytic leukemia at onset by determining the methylation status of the major breakpoint cluster region
CANCER GENETICS AND CYTOGENETICS
DNA methylation contributes to tissue- and allele-specific expression of the T-cell differentiation marker RT6
IMMUNOGENETICS
Regulation of the DNA methylation machinery and its role in cellular transformation
PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 69
DNA methylation analysis in immature testicular sperm cells at different developmental stages
UROLOGIA INTERNATIONALIS
The role of DNA methylation in mammalian epigenetics
SCIENCE
Imprinting and the epigenetic asymmetry between parental genomes
SCIENCE
Epigenetic reprogramming in mammalian development
SCIENCE
Investigating stem cells in human colon by using methylation patterns
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Methylation silencing and mutations of the p14(ARF) and p16(INK4a) genes in colon cancer
LABORATORY INVESTIGATION
Infection of lymphoid cells by integration-defective human immunodeficiency virus type 1 increases de novo methylation
JOURNAL OF VIROLOGY
Methylation of the E-cadherin gene promoter correlates with progression ofprostate cancer
JOURNAL OF UROLOGY
Methylation and colorectal cancer
JOURNAL OF PATHOLOGY
Concurrent hypermethylation of multiple genes is associated with grade of oligodendroglial tumors
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
Oligodendroglial tumors frequently demonstrate hypermethylation of the CDKN2A (MTS1, p16(INK4a)), p14(ARF), and CDKN2B (MTS2, p15(INK4b)) tumor suppressor genes
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
Methylation matters
JOURNAL OF MEDICAL GENETICS
A novel chromatin protein, distantly related to histone H2A, is largely excluded from the inactive X chromosome
JOURNAL OF CELL BIOLOGY
A protein kinase associated with apoptosis and tumor suppression - Structure, activity, and discovery of peptide substrates
JOURNAL OF BIOLOGICAL CHEMISTRY
Increased sensitivity of transforming growth factor (TGF) beta 1 null cells to alkylating agents reveals a novel link between TGF beta signaling and O-6-methylguanine methyltransferase promoter hypermethylation
JOURNAL OF BIOLOGICAL CHEMISTRY
A pancreatic beta-cell-specific enhancer in the human PIX-1 gene is regulated by hepatocyte nuclear factor 3 beta (HNF-3 beta), HNF-1 alpha, and SPs transcription factors
JOURNAL OF BIOLOGICAL CHEMISTRY
Sequence-specific DNA binding activity of RNA helicase A to the p16(INK4a)promoter
JOURNAL OF BIOLOGICAL CHEMISTRY
Aberrant expression of human mucin gene MUC5B in gastric carcinoma and cancer cells - Identification and regulation of a distal promoter
JOURNAL OF BIOLOGICAL CHEMISTRY
Hypermethylation of the CpG island of the RASSF1A gene in ovarian and renal cell carcinomas
INTERNATIONAL JOURNAL OF CANCER
Changes in P14(ARF) do not playa primary role in human chondrosarcoma tissues
INTERNATIONAL JOURNAL OF CANCER
Acquired resistance of melanoma cells to the antineoplastic agent fotemustine is caused by reactivation of the DNA repair gene MGMT
INTERNATIONAL JOURNAL OF CANCER
DNA methyltransferase expression and DNA methylation of CPG islands and peri-centromeric satellite regions in human colorectal and stomach cancers
INTERNATIONAL JOURNAL OF CANCER
Hypermethylation of the promoter region of the E-cadherin gene (CDH1) in sporadic and ulcerative colitis associated colorectal cancer
GUT
Imprinted expression of Neuronatin from modified BAC transgenes reveals regulation by distinct and distant enhancers
DEVELOPMENTAL BIOLOGY
In-tube DNA methylation profiling by fluorescence melting curve analysis
CLINICAL CHEMISTRY
A gene hypermethylation profile of human cancer
CANCER RESEARCH
Cytosine-phosphoguanine methylation of estrogen receptors in endometrial cancer
CANCER RESEARCH
Epigenetic patterns in the progression of esophageal adenocarcinoma
CANCER RESEARCH
p14(ARF) silencing by promoter hypermethylation mediates abnormal intracellular localization of MDM2
CANCER RESEARCH
Promoter methylation regulates Helicobacter pylori-stimulated cyclooxygenase-2 expression in gastric epithelial cells
CANCER RESEARCH
Promoter hypermethylation patterns of p16, O-6-methylguanine-DNA-methyltransferase, and death-associated protein kinase in tumors and saliva of head and neck cancer patients
CANCER RESEARCH
p16(INK4a) lesions are common, early abnormalities that undergo clonal expansion in Barrett's metaplastic epithelium
CANCER RESEARCH
Synergistic activation of functional estrogen receptor (ER)-alpha by DNA methyltransferase and histone deacetylase inhibition in human ER-alpha-negative breast cancer cells
CANCER RESEARCH
Frequent alterations of the p14(ARF) and p16(INK4a) genes in primary central nervous system lymphomas
CANCER RESEARCH
Loss of expression and aberrant methylation of the CDH13 (H-cadherin) genein breast and lung carcinomas
CANCER RESEARCH
High rates of loss of heterozygosity on chromosome 19p13 in human breast cancer
BRITISH JOURNAL OF CANCER
Methylation profiling in acute myeloid leukemia
BLOOD
Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia
BLOOD
Novel methylation targets in de novo acute myeloid leukemia with prevalence of chromosome 11 loci
BLOOD
DNA methylation and carcinogenesis
BIOCHEMISTRY-MOSCOW
Regulation of transcription of the glutathione S-transferase P1 gene by methylation of the minimal promoter in human leukemia cells
BIOCHEMICAL PHARMACOLOGY
High-throughput site-directed mutagenesis in ES cells
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS