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La ricerca find articoli where soggetti phrase all words 'CYTOSOLIC FREE CALCIUM' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 916 riferimenti
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    1. Dudek, SM; Garcia, JGN
      Cytoskeletal regulation of pulmonary vascular permeability

      JOURNAL OF APPLIED PHYSIOLOGY
    2. Evans, NH; McAinsh, MR; Hetherington, AM
      Calcium oscillations in higher plants

      CURRENT OPINION IN PLANT BIOLOGY
    3. Murali, B; Goyal, RK
      Improvement in insulin sensitivity by losartan in non-insulin-dependent diabetic (NIDDM) rats

      PHARMACOLOGICAL RESEARCH
    4. Schroeder, JI; Allen, GJ; Hugouvieux, V; Kwak, JM; Waner, D
      Guard cell signal transduction

      ANNUAL REVIEW OF PLANT PHYSIOLOGY AND PLANT MOLECULAR BIOLOGY
    5. Platoshyn, O; Yu, Y; Golovina, VA; McDaniel, SS; Krick, S; Li, L; Wang, JY; Rubin, LJ; Yuan, JXJ
      Chronic hypoxia decreases K-V channel expression and function in pulmonaryartery myocytes

      AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
    6. Rodriguez, MJ; Ursu, G; Bernal, F; Cusi, V; Mahy, N
      Perinatal human hypoxia-ischemia vulnerability correlates with brain calcification

      NEUROBIOLOGY OF DISEASE
    7. Evans, NH; Hetherington, AM
      Plant physiology: The ups and downs of guard cell signalling

      CURRENT BIOLOGY
    8. Webb, AAR; Larman, MG; Montgomery, LT; Taylor, JE; Hetherington, AM
      The role of calcium in ABA-induced gene expression and stomatal movements

      PLANT JOURNAL
    9. den Hartog, M; Musgrave, A; Munnik, T
      Nod factor-induced phosphatidic acid and diacylglycerol pyrophosphate formation: a role for phospholipase C and D in root hair deformation

      PLANT JOURNAL
    10. Karpati, I; Seres, I; Matyus, J; Ben, T; Paragh, G; Varga, Z; Kakuk, G
      Which parameters affect cytosolic free calcium in polymorphonuclear leukocytes of haemodialysis patients?

      NEPHROLOGY DIALYSIS TRANSPLANTATION
    11. Akimoto, T; Kusano, E; Fujita, N; Okada, K; Saito, O; Ono, S; Ando, Y; Homma, S; Saito, T; Asano, Y
      Erythropoietin modulates angiotensin II- or noradrenaline-induced Ca2+ mobilization in cultured rat vascular smooth-muscle cells

      NEPHROLOGY DIALYSIS TRANSPLANTATION
    12. Shilliday, IR; Allison, MEM
      Intraplatelet calcium levels in patients with acute renal failure before and after the administration of loop diuretics

      NEPHROLOGY DIALYSIS TRANSPLANTATION
    13. Lee, WK; Choi, SW; Lee, HR; Lee, EJ; Lee, KH; Kim, HO
      Purinoceptor-mediated calcium mobilization and proliferation in HaCaT keratinocytes

      JOURNAL OF DERMATOLOGICAL SCIENCE
    14. Shi, H; Norman, AW; Okamura, WH; Sen, A; Zemel, MB
      1 alpha,25-dihydroxyvitamin D-3 modulates human adipocyte metabolism via nongenomic action

      FASEB JOURNAL
    15. Berger, CEM; Rathod, H; Gillespie, JI; Horrocks, BR; Datta, HK
      Scanning electrochemical microscopy at the surface of bone-resorbing osteoclasts: Evidence for steady-state disposal and intracellular functional compartmentalization of calcium

      JOURNAL OF BONE AND MINERAL RESEARCH
    16. Dianzani, C; Lombardi, G; Collino, M; Ferrara, C; Cassone, MC; Fantozzi, R
      Priming effects of substance P on calcium changes evoked by interleukin-8 in human neutrophils

      JOURNAL OF LEUKOCYTE BIOLOGY
    17. Hauser, CJ; Fekete, Z; Adams, JM; Garced, M; Livingston, DH; Deitch, EA
      PAF-mediated Ca2+ influx in human neutrophils occurs via store-operated mechanisms

      JOURNAL OF LEUKOCYTE BIOLOGY
    18. Samnegard, E; Cullen, DM; Akhter, MP; Kimmel, DB
      No effect of verapamil on the local bone response to in vivo mechanical loading

      JOURNAL OF ORTHOPAEDIC RESEARCH
    19. Miura, T; Liu, YG; Goto, M; Tsuchida, A; Miki, T; Nakano, A; Nishino, YH; Ohnuma, Y; Shimamoto, K
      Mitochondrial ATP-sensitive K+ channels play a role in cardioprotection byNa+-H+ exchange inhibition against ischemia/reperfusion injury

      JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
    20. Chien, EJ; Hsieh, DJY; Wang, JEC
      Response of alkalinization or acidification by phytohemagglutinin is dependent on the activity protein kinase C in human peripheral T cells

      JOURNAL OF CELLULAR BIOCHEMISTRY
    21. Raudaskoski, M; Astrom, H; Laitiainen, E
      Pollen tube cytoskeleton: Structure and function

      JOURNAL OF PLANT GROWTH REGULATION
    22. Elzi, DJ; Bjornsen, AJ; MacKenzie, T; Wyman, TH; Silliman, CC
      Ionomycin causes activation of p38 and p42/44 mitogen-activated protein kinases in human neutrophils

      AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
    23. Ramasamy, R; Payne, JA; Whang, J; Bergmann, SR; Schaefer, S
      Protection of ischemic myocardium in diabetics by inhibition of electroneutral Na+-K+-2Cl(-) cotransporter

      AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
    24. Terrand, J; Papageorgiou, I; Rosenblatt-Velin, N; Lerch, R
      Calcium-mediated activation of pyruvate dehydrogenase in severely injured postischemic myocardium

      AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
    25. Xia, ZF; Zhao, PY; Horton, JW
      Changes in cardiac contractile function and myocardial [Ca2+](i) after burn trauma: NMR study

      AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
    26. Schafer, M; Bahde, D; Bosche, B; Ladilov, Y; Schafer, C; Piper, HM; Noll, T
      Modulation of early [Ca2+](i) rise in metabolically inhibited endothelial cells by xestospongin C

      AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
    27. Chen, Y; Rathbone, MP; Hertz, L
      Guanosine-induced increase in free cytosolic calcium concentration in mouse astrocytes in primary cultures: Does it act on an A3 adenosine receptor?

      JOURNAL OF NEUROSCIENCE RESEARCH
    28. Tyerman, SD; Beilby, M; Whittington, J; Juswono, U; Newman, I; Shabala, S
      Oscillations in proton transport revealed from simultaneous measurements of net current and net proton fluxes from isolated root protoplasts: MIFE meets patch-clamp

      AUSTRALIAN JOURNAL OF PLANT PHYSIOLOGY
    29. Oldroyd, GED
      Dissecting symbiosis: Developments in Nod factor signal transduction

      ANNALS OF BOTANY
    30. Xia, ZF; Horton, JW; Tang, HT; Yang, Y
      Metabolic disorder in myocardiac intracellular free calcium after thermal injury

      BURNS
    31. Wang, XY; Bergdahl, K; Heijbel, A; Liljebris, C; Bleasdale, JE
      Analysis of in vitro interactions of protein tyrosine phosphatase 1B with insulin receptors

      MOLECULAR AND CELLULAR ENDOCRINOLOGY
    32. Ramasamy, R; Liu, H; Cherednichenko, G; Schaefer, S
      Fasting limits the increase in intracellular calcium during ischemia in isolated rat hearts

      BASIC RESEARCH IN CARDIOLOGY
    33. Seki, S; Horikoshi, K; Takeda, H; Izumi, T; Nagata, A; Okumura, H; Taniguchi, M; Mochizuki, S
      Effects of sustained low-flow ischemia and reperfusion on Ca2+ transients and contractility in perfused rat hearts

      MOLECULAR AND CELLULAR BIOCHEMISTRY
    34. LaPointe, MS; Batlle, D
      Cultured skin fibroblasts as an in vitro model to assess phenotypic features in subjects with diabetic nephropathy

      AMERICAN JOURNAL OF KIDNEY DISEASES
    35. Grimaldi, M; Atzori, M; Ray, P; Alkon, DL
      Mobilization of calcium from intracellular stores, potentiation of neurotransmitter-induced calcium transients, and capacitative calcium entry by 4-aminopyridine

      JOURNAL OF NEUROSCIENCE
    36. Akimoto, T; Kusano, E; Ito, C; Yanagiba, S; Inoue, M; Amemiya, M; Ando, Y; Asano, Y
      Involvement of erythropoietin-induced cytosolic free calcium mobilization in activation of mitogen-activated protein kinase and DNA synthesis in vascular smooth muscle cells

      JOURNAL OF HYPERTENSION
    37. Grundler, W; Dirscherl, P; Beisker, W; Marx, K; Stampfl, A; Maier, K; Zimmermann, I; Nusse, M
      Early functional apoptotic responses of thymocytes induced by Tri-n-butyltin

      CYTOMETRY
    38. Tarnok, A; Ulrich, H
      Characterization of pressure-induced calcium response in neuronal cell lines

      CYTOMETRY
    39. Bouillier, H; Samain, E; Rucker-Martin, C; Renaud, JF; Safar, M; Dagher, G
      Effect of extracellular matrix elements on angiotensin II-induced calcium release in vascular smooth muscle cells from normotensive and hypertensive rats

      HYPERTENSION
    40. Barbagallo, M; Dominguez, LJ; Licata, G; Shan, J; Bing, L; Karpinski, E; Pang, PKT; Resnick, LM
      Vascular effects of progesterone - Role of cellular calcium regulation

      HYPERTENSION
    41. Reddy, ASN
      Calcium: silver bullet in signaling

      PLANT SCIENCE
    42. Zucchi, R; Ronca, F; Ronca-Testoni, S
      Modulation of sarcoplasmic reticulum function: a new strategy in cardioprotection?

      PHARMACOLOGY & THERAPEUTICS
    43. Sugiya, H; Mitsui, Y; Michikawa, H; Fujita-Yoshigaki, J; Hara-Yokoyama, M; Hashimoto, S; Furuyama, S
      Ca2+-regulated nitric oxide generation in rabbit parotid acinar cells

      CELL CALCIUM
    44. Chen, J; Liu, XL; Mandel, LJ; Schnellmann, RG
      Progressive disruption of the plasma membrane during renal proximal tubulecellular injury

      TOXICOLOGY AND APPLIED PHARMACOLOGY
    45. Horn, J; de Haan, RJ; Vermeulen, M; Luiten, PGM; Limburg, M
      Nimodipine in animal model experiments of focal cerebral ischemia - A systematic review

      STROKE
    46. Plieth, C
      Plant calcium signaling and monitoring: pros and cons and recent experimental approaches

      PROTOPLASMA
    47. Lionel, D; De Silva, R; Mansfield, TA; McAinsh, MR
      Changes in stomatal behaviour in the calcicole Leontodon hispidus due to the disruption by ozone of the regulation of apoplastic Ca2+ by trichomes

      PLANTA
    48. Johannes, E; Collings, DA; Rink, JC; Allen, NS
      Cytoplasmic pH dynamics in maize pulvinal cells induced induced by gravityvector changes

      PLANT PHYSIOLOGY
    49. Zhang, X; Zhang, L; Dong, FC; Gao, JF; Galbraith, DW; Song, CP
      Hydrogen peroxide is involved in abscisic acid-induced stomatal closure inVicia faba

      PLANT PHYSIOLOGY
    50. DeWald, DB; Torabinejad, J; Jones, CA; Shope, JC; Cangelosi, AR; Thompson, JE; Prestwich, GD; Hama, H
      Rapid accumulation of phosphatidylinositol 4,5-bisphosphate and inositol 1,4,5-trisphosphate correlates with calcium mobilization in salt-stressed Arabidopsis

      PLANT PHYSIOLOGY
    51. Minorsky, PV
      The hot and the classic

      PLANT PHYSIOLOGY
    52. Rudd, JJ; Franklin-Tong, VE
      Unravelling response-specificity in Ca2+ signalling pathways in plant cells

      NEW PHYTOLOGIST
    53. Ng, CKY; Mcainsh, MR; Gray, JE; Hunt, L; Leckie, CP; Mills, L; Hetherington, AM
      Calcium-based signalling systems in guard cells

      NEW PHYTOLOGIST
    54. Petrucci, C; Resta, V; Fieni, F; Bigiani, A; Bagnoli, P
      Modulation of potassium current and calcium influx by somatostatin in rod bipolar cells isolated from the rabbit retina via sst(2) receptors

      NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
    55. Allen, GJ; Chu, SP; Harrington, CL; Schumacher, K; Hoffman, T; Tang, YY; Grill, E; Schroeder, JL
      A defined range of guard cell calcium oscillation parameters encodes stomatal movements

      NATURE
    56. Ng, CKY; Carr, K; McAinsh, MR; Powell, B; Hetherington, AM
      Drought-induced guard cell signal transduction involves sphingosine-1-phosphate

      NATURE
    57. Moutinho, A; Hussey, PJ; Trewavas, AJ; Malho, R
      cAMP acts as a second messenger in pollen tube growth and reorientation

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    58. Fukuda, H; Luo, CS; Gu, X; Guo, LL; Digerness, SB; Li, JX; Pike, MM
      The effect of K-ATP channel activation on myocardial cationic and energetic status during ischemia and reperfusion: Role in cardioprotection

      JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
    59. Whitehead, JP; Molero, JC; Clark, S; Martin, S; Meneilly, G; James, DE
      The role of Ca2+ in insulin-stimulated glucose transport in 3T3-L1 cells

      JOURNAL OF BIOLOGICAL CHEMISTRY
    60. Satoh, E; Ishii, T; Nishimura, M
      The mechanism of maitotoxin-induced elevation of the cytosolic free calcium level in rat cerebrocortical synaptosomes

      JAPANESE JOURNAL OF PHARMACOLOGY
    61. Hamilton, DWA; Hills, A; Blatt, MR
      Extracellular Ba2+ and voltage interact to gate Ca2+ channels at the plasma membrane of stomatal guard cells

      FEBS LETTERS
    62. Bosco, D; Gonelle-Gispert, C; Wollheim, CB; Halban, PA; Rouiller, DG
      Increased intracellular calcium is required for spreading of rat islet beta-cells on extracellular matrix

      DIABETES
    63. Sandmann, S; Yu, MH; Unger, T
      Transcriptional and translational regulation of calpain in the rat heart after myocardial infarction - effects of AT(1) and AT(2) receptor antagonists and ACE inhibitor

      BRITISH JOURNAL OF PHARMACOLOGY
    64. Kim, DK; Oh, EK; Summers, BA; Prabhakar, NR; Kumar, GK
      Release of substance P by low oxygen in the rabbit carotid body: evidence for the involvement of calcium channels

      BRAIN RESEARCH
    65. Dong, Z; Venkatachalam, MA; Weinberg, JM; Saikumar, P; Patel, Y
      Protection of ATP-depleted cells by impermeant strychnine derivatives - Implications for glycine cytoprotection

      AMERICAN JOURNAL OF PATHOLOGY
    66. Bierne, H; Dramsi, S; Gratacap, MP; Randriamampita, C; Carpenter, G; Payrastre, B; Cossart, P
      The invasion protein InIB from Listeria monocytogenes activates PLC-gamma 1 downstream from PI 3-kinase

      CELLULAR MICROBIOLOGY
    67. Blatt, MR
      Ca2+ signalling and control of guard-cell volume in stomatal movements

      CURRENT OPINION IN PLANT BIOLOGY
    68. Shi, H; Halvorsen, YD; Ellis, PN; Wilkison, WO; Zemel, MB
      Role of intracellular calcium in human adipocyte differentiation

      PHYSIOLOGICAL GENOMICS
    69. Blatt, MR
      Cellular signaling and volume control in stomatal movements in plants

      ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY
    70. Chang, DC; Lu, P
      Multiple types of calcium signals are associated with cell division in zebrafish embryo

      MICROSCOPY RESEARCH AND TECHNIQUE
    71. Anversa, P; Leri, A; Li, B; Liu, Y; Di Somma, S; Kajstura, J
      Ischemic cardiomyopathy and the cellular renin-angiotensin system

      JOURNAL OF HEART AND LUNG TRANSPLANTATION
    72. Geitmann, A; Snowman, BN; Emons, AMC; Franklin-Tong, VE
      Alterations in the actin cytoskeleton of pollen tubes are induced by the self-incompatibility reaction in Papaver rhoeas

      PLANT CELL
    73. Fogelholm, R; Erila, T; Palomaki, H; Murros, K; Kaste, M
      Effect of nimodipine on final infarct volume after acute ischemic stroke

      CEREBROVASCULAR DISEASES
    74. Morello, L; Frattini, M; Giani, S; Christou, P; Breviario, D
      Overexpression of the calcium-dependent protein kinase OsCDPK2 in transgenic rice is repressed by light in leaves and disrupts seed development

      TRANSGENIC RESEARCH
    75. Felle, HH; Hanstein, S; Steinmeyer, R; Hedrich, R
      Dynamics of ionic activities in the apoplast of the sub-stomatal cavity ofintact Vicia faba leaves during stomatal closure evoked by ABA and darkness

      PLANT JOURNAL
    76. Wood, NT; Allan, AC; Haley, A; Viry-Moussaid, M; Trewavas, AJ
      The characterization of differential calcium signalling in tobacco guard cells

      PLANT JOURNAL
    77. Jordan, ND; Franklin, FCH; Franklin-Tong, VE
      Evidence for DNA fragmentation triggered in the self-incompatibility response in pollen of Papaver rhoeas

      PLANT JOURNAL
    78. Kiegle, E; Moore, CA; Haseloff, J; Tester, MA; Knight, MR
      Cell-type-specific calcium responses to drought, salt and cold in the Arabidopsis root

      PLANT JOURNAL
    79. Williams, H; Kerr, PM; Suleiman, MS; Griffiths, EJ
      Differences in the calcium-handling response of isolated rat and guinea-pig cardiomyocytes to metabolic inhibition: implications for cell damage

      EXPERIMENTAL PHYSIOLOGY
    80. Oshiro, T; Kakuta, Y; Shimura, S; Nara, M; Shirato, K
      Characterization of platelet-activating factor-induced cytosolic calcium mobilization in human eosinophils

      CLINICAL AND EXPERIMENTAL ALLERGY
    81. Isozaki, H; Fujii, K; Nomura, E; Hara, H
      Calcium concentration in hepatocytes during liver ischaemia-reperfusion injury and the effects of diltiazem and citrate on perfused rat liver

      EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
    82. Tian, HQ; Zhu, H; Russell, SD
      Calcium changes in ovules and embryo sacs of Plumbago zeylanica L.

      SEXUAL PLANT REPRODUCTION
    83. Edelstein, CL
      Calcium-mediated proximal tubular injury - what is the role of cysteine proteases?

      NEPHROLOGY DIALYSIS TRANSPLANTATION
    84. Hemmingsen, C
      Regulation of renal Calbindin-D28k

      PHARMACOLOGY & TOXICOLOGY
    85. Kalliovalkama, J; Kahonen, M; Tolvanen, JP; Wu, XM; Voipio, J; Pekki, A; Doris, PA; Ylitalo, P; Porsti, I
      Arterial responses in vitro and plasma digoxin immunoreactivity after losartan and enalapril treatments in experimental hypertension

      PHARMACOLOGY & TOXICOLOGY
    86. Zemel, MB; Shi, H; Greer, B; Dirienzo, D; Zemel, PC
      Regulation of adiposity by dietary calcium

      FASEB JOURNAL
    87. Jian, LC; Li, JH; Li, PH
      Seasonal alteration in amount of Ca2+ in apical bud cells of mulberry (Morus bombciz Koidz): an electron microscopy-cytochemical study

      TREE PHYSIOLOGY
    88. Kupriyanov, VV; Xiang, B; Sun, J; Jilkina, O; Dai, G; Deslauriers, R
      Effects of ischemia on intracellular rubidium in pig and rat hearts: Rb-87NMR imaging and spectroscopic study

      MAGNETIC RESONANCE IN MEDICINE
    89. Pandey, S; Tiwari, SB; Upadhyaya, KC; Sopory, SK
      Calcium signaling: Linking environmental signals to cellular functions

      CRITICAL REVIEWS IN PLANT SCIENCES
    90. Lin, YC; Lyle, RM; McCabe, LD; McCabe, GP; Weaver, CM; Teegarden, D
      Dairy calcium is related to changes in body composition during a two-year exercise intervention in young women

      JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION
    91. Kuo, JS; Cheng, FC; Shen, CC; Ou, HC; Wu, TF; Huang, HM
      Differential alteration of catecholamine release during chemical hypoxia is correlated with cell toxicity and is blocked by protein kinase C inhibitors in PC12 cells

      JOURNAL OF CELLULAR BIOCHEMISTRY
    92. Chen, LY; Chiang, AS; Hung, JJ; Hung, HI; Lai, YK
      Thapsigargin-induced Grp78 expression is mediated by the increase of cytosolic free calcium in 9L rat brain tumor cells

      JOURNAL OF CELLULAR BIOCHEMISTRY
    93. Kato, E; Taguchi, A; Sakashita, S; Akiyoshi, K; Sunamoto, J
      Synthesis and function of sialic acid-conjugated cholesterols as ganglioside analogs: their reconstitution to liposomes and interaction with rat lymphocytes

      PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES
    94. Huang, HM; Ou, HC; Hsieh, SJ
      Amyloid beta peptide impaired carbachol but not glutamate-mediated phosphoinositide pathways in cultured rat cortical neurons

      NEUROCHEMICAL RESEARCH
    95. Griffin, JL; White, LT; Lewandowski, ED
      Substrate-dependent proton load and recovery of stunned hearts during pyruvate dehydrogenase stimulation

      AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
    96. Huang, MS; Adebanjo, OA; Awumey, E; Biswas, G; Koval, A; Sodam, BR; Sun, L; Moonga, BS; Epstein, J; Goldstein, S; Lai, FA; Lipschitz, D; Zaidi, M
      IP3, IP3 receptor, and cellular senescence

      AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
    97. Lieberthal, W; Nigam, SK; Molitoris, BA; Weinberg, JM; Venkatachalam, MA; Zager, RA; Nath, KA; Goligorsky, MS
      Acute renal failure. II. Experimental models of acute renal failure: imperfect but indispensable

      AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
    98. Snowman, BN; Geitmann, A; Clarke, SR; Staiger, CJ; Franklin, FCH; Emons, AMC; Franklin-Tong, VE
      Signalling and the cytoskeleton of pollen tubes of Papaver rhoeas

      ANNALS OF BOTANY
    99. Malho, R; Camacho, L; Moutinho, A
      Signalling pathways in pollen tube growth and reorientation

      ANNALS OF BOTANY
    100. Sherer, TB; Clemow, DB; Tuttle, JB
      Calcium homeostasis and nerve growth factor secretion from vascular and bladder smooth muscle cells

      CELL AND TISSUE RESEARCH


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Documento generato il 24/01/21 alle ore 05:14:22