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Disruption of their palindromic arrangement leads to selective loss of DNAmethylation in inversely repeated gus transgenes in Arabidopsis
MOLECULAR GENETICS AND GENOMICS
DNA methylation inhibits expression and transposition of the Neurospora Tad retrotransposon
MOLECULAR GENETICS AND GENOMICS
Stability and inheritance of methylation states at PstI sites in Pisum
MOLECULAR GENETICS AND GENOMICS
Metal-nucleobase interaction: dibromobis(cytosine)cadmium(II)
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE
Use of artificial neural networks for the evaluation of electrochemical signals of adenine and cytosine in mixtures interfered with hydrogen evolution
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
Clinical applications of a novel sustained-release injectable drug delivery system: DepoFoam (TM) technology
CANCER JOURNAL
Cloning and sequence analysis of a zebrafish cDNA encoding DNA (cytosine-5)-methyltransferase-1
GENESIS
Costs of diagnosis, treatment, and follow up of patients with acute myeloid leukemia in the Netherlands
JOURNAL OF HEMATOTHERAPY & STEM CELL RESEARCH
Inhibition of (cytosine C5)-methyltransferase by oligonucleotides containing flexible (cyclopentane) and conformationally constrained (bicyclo[3.1.0]hexane) abasic sites
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
Unnatural enantiomers of 5-azacytidine analogues: Syntheses and enzymatic properties
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
Intra-arterial delivery of a recombinant adenovirus does not increase genetransfer to tumor cells in a rat model of metastatic colorectal carcinoma
MOLECULAR THERAPY
Combined adenovirus-mediated nitroreductase gene delivery and CB1954 treatment: A well-tolerated therapy for established solid tumors
MOLECULAR THERAPY
Global methylation profiling of lung cancer identifies novel methylated genes
NEOPLASIA
Treatment of acute myeloid leukaemia in younger patients
BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY
How nucleobases rotate when bonded to a metal ion: Detailed view from an ab initio quantum chemical study of a cytosine complex of trans-a(2)Pt(II)
JOURNAL OF PHYSICAL CHEMISTRY B
Interactions of hydrated Mg2+ cation with bases, base pairs, and nucleotides. Electron topology, natural bond orbital, electrostatic, and vibrationalstudy
JOURNAL OF PHYSICAL CHEMISTRY B
A novel theoretical model for molecular recognition of multiple-site interacting systems using density response functions
JOURNAL OF PHYSICAL CHEMISTRY B
Lithium affinity for DNA and RNA nucleobases. The role of theoretical information in the elucidation of the mass spectrometry data
JOURNAL OF PHYSICAL CHEMISTRY B
Efficacy and safety of gemtuzumab ozogamicin in patients with CD33-positive acute myeloid leukaemia in first relapse
EXPERT OPINION ON BIOLOGICAL THERAPY
Gene therapy for high grade gliomas
EXPERT OPINION ON BIOLOGICAL THERAPY
ENDOR study of the chlorinated thiocytosine radical in a crystal matrix
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
The influence of square planar platinum complexes on DNA base pairing. An ab initio DFT study
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
Sigma radicals in gamma-irradiated single crystals of 2-thiothymine
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
Improvement in precision of the liquid chromatographic-electrospray ionization tandem mass spectrometric analysis of 3 '-C-ethynylcytidine in rat plasma
JOURNAL OF CHROMATOGRAPHY B
Micellar electrokinetic capillary chromatography quantification of cytosine arabinoside and its metabolite, uracil arabinoside, in human serum
JOURNAL OF CHROMATOGRAPHY B
Bisulfite-induced cytosine deamination rates in E-coli SSB : DNA complexes
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
Extent of CpG methylation is not proportional to the in vivo spontaneous mutation frequency at transgenic loci in Big Blue (TM) rodents
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
Quantum chemistry predicted correlations between geometric isomerism (conformation) of -OH and =NH substituents and typical group frequencies of nucleic acid bases: cytosine
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
Gene silencing and DNA methylation processes
CURRENT OPINION IN PLANT BIOLOGY
Silencing of transposable elements in plants
TRENDS IN PLANT SCIENCE
Axial guanine binding to a diplatinum(III) core
CHEMICAL COMMUNICATIONS
Extreme (10(9)) acidification of adenine-NH2 in an open platinated nucleobase quartet. A pH switch with potential as a biological acid/base catalyst
CHEMICAL COMMUNICATIONS
Vinblastin-carboplatin for metastatic cutaneous melanoma as first-line chemotherapy and in dacarbazine failures - A single-center study
MEDICAL ONCOLOGY
Does cytosine-thymine-guanine (CTG) expansion size predict cardiac events and electrocardiographic progression in myotonic dystrophy?
HEART
Convection-enhanced intraparenchymal delivery (CEID) of cytosine arabinoside (AraC) for the treatment of HIV-related progressive multifocal leukoencephalopathy (PML)
JOURNAL OF NEUROVIROLOGY
Gene therapy for colorectal cancer - Therapeutic potential
BIODRUGS
The efficacy of 1-beta-D-arabinofuranosylcytosine entrapped in niosomes against leuk ae mia in mice
STP PHARMA SCIENCES
Cloning and expression of uridine/cytidine kinase cDNA from human fibrosarcoma cells
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
The role of DNA methyltransferase 1 in growth control
FRONTIERS IN BIOSCIENCE
Theoretical study of tautomeric forms of uracil. 1. Relative order of stabilities and their relation to proton affinities and deprotonation enthalpies
JOURNAL OF PHYSICAL CHEMISTRY A
Ab initio study of the crystallographic solvation pattern of the cytosine-guanine base pair in DNA
JOURNAL OF PHYSICAL CHEMISTRY A
CASSCF investigation of electronic excited states of 2-aminopurine
JOURNAL OF PHYSICAL CHEMISTRY A
Strategies to accomplish targeted expression of transgenes in ovarian cancer for molecular therapeutic applications
CLINICAL CANCER RESEARCH
Approval summary: Gemtuzumab ozogamicin in relapsed acute myeloid leukemia
CLINICAL CANCER RESEARCH
Relationship of chromosome 21 and acute leukemia in children with Down syndrome
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
PNA synthesis using a novel Boc/acyl protecting group strategy
JOURNAL OF PEPTIDE SCIENCE
A Taq attack displaces bases
NATURE STRUCTURAL BIOLOGY
Structure of the N6-adenine DNA methyltransferase M center dot Taql in complex with DNA and a cofactor analog
NATURE STRUCTURAL BIOLOGY
Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation
NATURE GENETICS
Use of cidofovir in progressive multifocal leukoencephalopathy
ANNALS OF PHARMACOTHERAPY
Prospects for viral-based strategies enhancing the anti-tumor effects of ionizing radiation
SEMINARS IN RADIATION ONCOLOGY
Complete sequencing of mono-deprotonated peptide nucleic acids by sustained off-resonance irradiation collision-induced dissociation
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
Cationic liposome-mediated gene delivery to the liver and to hepatocellular carcinomas in mice
HUMAN GENE THERAPY
Adenovirus gene transfer vectors inhibit growth of lymphatic tumor metastases independent of a therapeutic transgene
HUMAN GENE THERAPY
Interferon-alpha combined with cytarabine in chronic myelogenous leukemia - Clinical benefits
LEUKEMIA & LYMPHOMA
Fludarabine and cytarabine as a sequential infusion regimen for treatment of adults with recurrent, refractory or poor prognosis acute leukemia
LEUKEMIA & LYMPHOMA
High remission rate in acute myeloblastic leukemia with only two days of chemotherapy
LEUKEMIA & LYMPHOMA
Cytarabine added to interferon improves the cost-effectiveness of initial therapy for patients with early chronic phase chronic myelogenous leukemia
LEUKEMIA & LYMPHOMA
Treatment of "poor risk" acute myeloid leukemia with fludarabine, cytarabine and G-CSF (FLAG regimen): A single center study
LEUKEMIA & LYMPHOMA
First line therapy with fludarabine combinations in 42 patients with either post myelodysplastic syndrome or therapy related acute myeloid leukaemia
LEUKEMIA & LYMPHOMA
Leukemia cutis in an elderly patient treated with low dose cytosine arabinoside and etoposide
LEUKEMIA & LYMPHOMA
Acute myeloid leukemia in the elderly: biology and therapeutic strategies
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
Pharmacological aspects of targeting cancer gene therapy to endothelial cells
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
Intrathecal chemotherapy
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
Chromobacterium violaceum: A review of pharmacological and industiral perspectives
CRITICAL REVIEWS IN MICROBIOLOGY
The effect of the gene encoding EcoRII DNA methyltransferase on the phenotype of transgenic tumor cell lines of Nicotiana tabacum and the methylationlevel of CpNpG sequences in their genome
RUSSIAN JOURNAL OF PLANT PHYSIOLOGY
Selective protection of mitogenically stimulated human lymphocytes but notleukemic cells from cytosine arabinoside-induced apoptosis by LY294002, a phosphoinositol-3 kinase inhibitor
INTERNATIONAL JOURNAL OF ONCOLOGY
Amelioration of retrovirus-mediated gene transfer into hepatocellular carcinoma cells
INTERNATIONAL JOURNAL OF ONCOLOGY
Bystander effect in uracil phosphoribosyltransferase 5-fluorouracil-mediated suicide gene therapy is correlated with the level of intercellular communication
INTERNATIONAL JOURNAL OF ONCOLOGY
Design and synthesis of novel peptide nucleic acid monomers
CHINESE JOURNAL OF CHEMISTRY
Suicide gene therapy for premalignant disease: a new strategy for the treatment of intraepithelial neoplasia
GENE THERAPY
Enhanced suicide gene effect by adenoviral transduction of a VP22-cytosinedeaminase (CD) fusion gene
GENE THERAPY
Hepatic intra-arterial delivery of a retroviral vector expressing the cytosine deaminase gene, controlled by the CEA promoter and intraperitoneal treatment with 5-fluorocytosine suppresses growth of colorectal liver metastases
GENE THERAPY
Gene delivery from the E3 region of replicating human adenovirus: evaluation of the 6.7 K/gp19 K region
GENE THERAPY
Cell surface display of a lysosomal enzyme for extracellular gene-directedenzyme prodrug therapy
GENE THERAPY
Functional production of mammalian concentrative nucleoside transporters in Saccharomyces cerevisiae
MOLECULAR MEMBRANE BIOLOGY
Construction of peptide conjugates with peptide nucleic acids containing an anthracene probe and their interactions with DNA
BIOORGANIC & MEDICINAL CHEMISTRY
Synthesis and cytotoxicity of 4 '-C- and 5 '-C-substituted toyocamycins
BIOORGANIC & MEDICINAL CHEMISTRY
Transcriptional activity of an inversion split NOR in barley (Hordeum vulgare L.)
CHROMOSOME RESEARCH
Comparative karyology, DNA methylation and restriction pattern analysis ofmale and female plants of the dioecious alga Chara tomentosa (Charophyceae)
EUROPEAN JOURNAL OF PHYCOLOGY
RNA-directed transcriptional gene silencing in plants can be inherited independently of the RNA trigger and requires Met1 for maintenance
CURRENT BIOLOGY
Gene-associated CpG islands in plants as revealed by analyses of genomic sequences
PLANT JOURNAL
Gene therapy for hepatocellular carcinoma based on tumour-selective suicide gene expression using the alpha-fetoprotein (AFP) enhancer and a housekeeping gene promoter
EUROPEAN JOURNAL OF CANCER
Increased sensitivity to cytosine arabinoside in human leukemia by c-raf-1antisense oligonucleotides
ANTI-CANCER DRUGS
Epigenetic developmental mechanisms in plants: molecules and targets of plant epigenetic regulation
CURRENT OPINION IN GENETICS & DEVELOPMENT
Suicide gene therapy: possible applications in haematopoietic disorders
JOURNAL OF INTERNAL MEDICINE
DNA methylation, methyltransferases, and cancer
ONCOGENE
Escherichia coli DNA glycosylase Mug: a growth-regulated enzyme required for mutation avoidance in stationary-phase cells
MOLECULAR MICROBIOLOGY
Metal-modified nucleobase sextet: Joining four linear metal fragments (trans-a(2)Pt(II)) and six model nucleobases to an exceedingly stable entity
CHEMISTRY-A EUROPEAN JOURNAL
Suicide gene therapy for pediatric tumors
JOURNAL OF MOLECULAR MEDICINE-JMM
Single-agent therapy with oral mercaptopurine for nonlymphoid blast crisisof chronic myeloid leukemia
ANNALS OF HEMATOLOGY
Efficacy of fludarabine, intermittent sequential high-dose cytosine arabinoside, and mitoxantrone [FIS-HAM] salvage therapy in highly resistant acuteleukemias
ANNALS OF HEMATOLOGY
Selection of drug-resistant transduced cells with cytosine nucleoside analogs using the human cytidine deaminase gene
CANCER GENE THERAPY
Specific targeting of cytosine deaminase to solid tumors by engineered Clostridium acetobutylicum
CANCER GENE THERAPY
Evaluation of a new dual-specificity promoter for selective induction of apoptosis in breast cancer cells
CANCER GENE THERAPY
Herpes simplex virus thymidine kinase/ganciclovir-induced cell death is enhanced by co-expression of caspase-3 in ovarian carcinoma cells
CANCER GENE THERAPY
Effect of granulocyte colony-stimulating factor on chemotherapeutic activity of cytosine arabinoside in acute leukemic cell lines
INTERNATIONAL JOURNAL OF HEMATOLOGY
Enhanced loop DNA folding induced by thymine-CH3 group contact and perpendicular guanine-thymine interaction
JOURNAL OF BIOMOLECULAR NMR
Characterization of functional interactions among the Escherichia coli mismatch repair proteins using a bacterial two-hybrid assay
MUTATION RESEARCH-DNA REPAIR
Suicide gene therapy on LNCaP human prostate cancer cells
INTERNATIONAL JOURNAL OF UROLOGY