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La ricerca find articoli where soggetti phrase all words 'CYP2A6' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 51 riferimenti
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    1. Komatsu, T; Yamazaki, H; Shimada, N; Nagayama, S; Kawaguchi, Y; Nakajima, M; Yokoi, T
      Involvement of microsomal cytochrome P450 and cytosolic thymidine phosphorylase in 5-fluorouracil formation from tegafur in human liver

      CLINICAL CANCER RESEARCH
    2. Yang, MH; Kunugita, N; Kitagawa, K; Kang, SH; Coles, B; Kadlubar, FF; Katoh, T; Matsuno, K; Kawamoto, T
      Individual differences in urinary cotinine levels in Japanese smokers: Relation to genetic polymorphism of drug-metabolizing enzymes

      CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
    3. Oscarson, M
      Nicotine metabolism by the polymorphic cytochrome P450 2A6 (CYP2A6) enzyme: Implications for interindividual differences in smoking behaviour target article on nicotine-addiction

      PSYCOLOQUY
    4. Cok, I; Kocabas, NA; Cholerton, S; Karakaya, AE; Sardas, S
      Determination of coumarin metabolism in Turkish population

      HUMAN & EXPERIMENTAL TOXICOLOGY
    5. Loriot, MA; Rebuissou, S; Oscarson, M; Cenee, S; Miyamoto, M; Ariyoshi, N; Kamataki, T; Hemon, D; Beaune, P; Stucker, I
      Genetic polymorphisms of cytochrome P450 2A6 in a case-control study on lung cancer in a French population

      PHARMACOGENETICS
    6. Murayama, N; Sai, K; Nakajima, Y; Kaniwa, N; Ozawa, S; Ohno, Y; Sawada, J
      Expression of CYP2A6 in turner cells augments cellular sensitivity to tegafur

      JAPANESE JOURNAL OF CANCER RESEARCH
    7. Gonzalez, FJ
      The use of gene knockout mice to unravel the mechanisms of toxicity and chemical carcinogenesis

      TOXICOLOGY LETTERS
    8. Raunio, H; Rautio, A; Gullsten, H; Pelkonen, O
      Polymorphisms of CYP2A6 and its practical consequences

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    9. Benowitz, NL; Jacob, P
      Trans-3 '-hydroxycotinine: Disposition kinetics, effects and plasma levelsduring cigarette smoking

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    10. Paschke, T; Riefler, M; Schuler-Metz, A; Wolz, L; Scherer, G; McBride, CM; Bepler, G
      Comparison of cytochrome P450 2A6 polymorphism frequencies in Caucasians and African-Americans using a new one-step PCR-RFLP genotyping method

      TOXICOLOGY
    11. Tyndale, RF; Sellers, EM
      Variable CYP2A6-mediated nicotine metabolism alters smoking behavior and risk

      DRUG METABOLISM AND DISPOSITION
    12. Kitagawa, K; Kunugita, N; Kitagawa, M; Kawamoto, T
      CYP2A6*6, a novel polymorphism in cytochrome P450 2A6, has a single amino acid substitution (R128Q) that inactivates enzymatic activity

      JOURNAL OF BIOLOGICAL CHEMISTRY
    13. Tan, W; Chen, GF; Xing, DY; Song, CY; Kadlubar, FF; Lin, DX
      Frequency of CYP2A6 gene deletion and its relation to risk of lung and esophageal cancer in the Chinese population

      INTERNATIONAL JOURNAL OF CANCER
    14. Rodriguez-Antona, C; Donato, MT; Pareja, E; Gomez-Lechon, MJ; Castell, JV
      Cytochrome P-450 mRNA expression in human liver and its relationship with enzyme activity

      ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
    15. Bendriss, EK; Markoglou, N; Wainer, IW
      Liquid chromatographic method for the simultaneous determination of caffeine and fourteen caffeine metabolites in urine

      JOURNAL OF CHROMATOGRAPHY B
    16. Born, SL; Caudill, D; Smith, BJ; Lehman-McKeeman, LD
      In vitro kinetics of coumarin 3,4-epoxidation: Application to species differences in toxicity and carcinogenicity

      TOXICOLOGICAL SCIENCES
    17. Diaz, GJ; Squires, EJ
      Metabolism of 3-methylindole by porcine liver microsomes: Responsible cytochrome P450 enzymes

      TOXICOLOGICAL SCIENCES
    18. Ikeda, K; Yoshisue, K; Matsushima, E; Nagayama, S; Kobayashi, K; Tyson, CA; Chiba, K; Kawaguchi, Y
      Bioactivation of tegafur to 5-fluorouracil is catalyzed by cytochrome P-450 2A6 in human liver microsomes in vitro

      CLINICAL CANCER RESEARCH
    19. Chowdhury, P; Rayford, PL
      Smoking and pancreatic disorders

      EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
    20. Inoue, K; Yamazaki, H; Shimada, T
      CYP2A6 genetic polymorphisms and liver microsomal coumarin and nicotine oxidation activities in Japanese and Caucasians

      ARCHIVES OF TOXICOLOGY
    21. Bourian, M; Gullsten, H; Legrum, W
      Genetic polymorphism of CYP2A6 in the German population

      TOXICOLOGY
    22. Pelkonen, O; Rautio, A; Raunio, H; Pasanen, M
      CYP2A6: a human coumarin 7-hydroxylase

      TOXICOLOGY
    23. Rao, YS; Hoffmann, E; Zia, M; Bodin, L; Zeman, M; Sellers, EM; Tyndale, RF
      Duplications and defects in the CYP2A6 gene: Identification, genotyping, and in vivo effects on smoking

      MOLECULAR PHARMACOLOGY
    24. Arinami, T; Ishiguro, H; Onaivi, ES
      Polymorphisms in genes involved in neurotransmission in relation to smoking

      EUROPEAN JOURNAL OF PHARMACOLOGY
    25. Sellers, EM; Kaplan, HL; Tyndale, RF
      Inhibition of cytochrome P450 2A6 increases nicotine's oral bioavailability and decreases smoking

      CLINICAL PHARMACOLOGY & THERAPEUTICS
    26. Benowitz, NL; Jacob, P
      Effects of cigarette smoking and carbon monoxide on nicotine and cotinine metabolism

      CLINICAL PHARMACOLOGY & THERAPEUTICS
    27. Dempsey, D; Jacob, P; Benowitz, NL
      Nicotine metabolism and elimination kinetics in newborns

      CLINICAL PHARMACOLOGY & THERAPEUTICS
    28. Nakajima, M; Yamagishi, S; Yamamoto, H; Yamamoto, T; Kuroiwa, Y; Yokoi, T
      Deficient cotinine formation from nicotine is attributed to the whole deletion of the CYP2A6 gene in humans

      CLINICAL PHARMACOLOGY & THERAPEUTICS
    29. Bohets, H; Lavrijsen, K; Hendrickx, J; van Houdt, J; van Genechten, V; Verboven, P; Meuldermans, W; Heykants, J
      Identification of the cytochrome P450 enzymes involved in the metabolism of cisapride: in vitro studies of potential co-medication interactions

      BRITISH JOURNAL OF PHARMACOLOGY
    30. Gu, DF; Hinks, LJ; Morton, NE; Day, INM
      The use of long PCR to confirm three common alleles at the CYP2A6 locus and the relationship between genotype and smoking habit

      ANNALS OF HUMAN GENETICS
    31. Soucek, P
      Novel sensitive high-performance liquid chromatographic method for assay of coumarin 7-hydroxylation

      JOURNAL OF CHROMATOGRAPHY B
    32. Kamataki, T; Nunoya, K; Sakai, Y; Kushida, H; Fujita, K
      Genetic polymorphism of CYP2A6 in relation to cancer

      MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
    33. Chen, GF; Tang, YM; Green, B; Lin, DX; Guengerich, FP; Daly, AK; Caporaso, NE; Kadlubar, FF
      Low frequency of CYP2A6 gene polymorphism as revealed by a one-step polymerase chain reaction method

      PHARMACOGENETICS
    34. Sai, Y; Yang, TJ; Krausz, KW; Gonzalez, FJ; Gelboin, HV
      An inhibitory monoclonal antibody to human cytochrome P450 2A6 defines itsrole in the metabolism of coumarin, 7-ethoxycoumarin and 4-nitroanisole inhuman liver

      PHARMACOGENETICS
    35. Bourian, M; Runkel, M; Krisp, A; Tegtmeier, M; Freudenstein, J; Legrum, W
      Naringenin and interindividual variability in interaction of coumarin withgrapefruit juice

      EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY
    36. Murphy, SE; Johnson, LM; Pullo, DA
      Characterization of multiple products of cytochrome P450 2A6-catalyzed cotinine metabolism

      CHEMICAL RESEARCH IN TOXICOLOGY
    37. Yamazaki, H; Inoue, K; Hashimoto, M; Shimada, T
      Roles of CYP2A6 and CYP2B6 in nicotine C-oxidation by human liver microsomes

      ARCHIVES OF TOXICOLOGY
    38. Lewis, DFV; Dickens, M; Lake, BG; Eddershaw, PJ; Tarbit, MH; Goldfarb, PS
      Molecular modelling of the human cytochrome P450 isoform CYP2A6 and investigations of CYP2A substrate selectivity

      TOXICOLOGY
    39. Oscarson, M; McLellan, RA; Gullsten, H; Agundez, JAG; Benitez, J; Rautio, A; Raunio, H; Pelkonen, O; Ingelman-Sundberg, M
      Identification and characterisation of novel polymorphisms in the CYP2A locus: implications for nicotine metabolism

      FEBS LETTERS
    40. Oscarson, M; McLellan, RA; Gullsten, H; Yue, QY; Lang, MA; Bernal, ML; Sinues, B; Hirvonen, A; Raunio, H; Pelkonen, O; Ingelman-Sundberg, M
      Characterisation and PCR-based detection of a CYP2A6 gene deletion found at a high frequency in a Chinese population

      FEBS LETTERS
    41. Chen, SC; Wang, XJ; Xu, GP; Zhou, L; Vennerstrom, JL; Gonzalez, F; Gelboin, HV; Mirvish, SS
      Depentylation of [H-3-pentyl]methyl-n-amylnitrosamine by rat esophageal and liver microsomes and by rat and human cytochrome p450 isoforms

      CANCER RESEARCH
    42. Kitagawa, K; Kunugita, N; Katoh, T; Yang, MH; Kawamoto, T
      The significance of the homozygous CYP2A6 deletion on nicotine metabolism:A new genotyping method of CYP2A6 using a single PCR-RFLP

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    43. Miyamoto, M; Umetsu, Y; Dosaka-Akita, H; Sawamura, Y; Yokota, J; Kunitoh, H; Nemoto, N; Sato, K; Ariyoshi, N; Kamataki, T
      CYP2A6 gene deletion reduces susceptibility to lung cancer

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    44. Soucek, P
      Expression of cytochrome P450 2A6 in Escherichia coli: Purification, spectral and catalytic characterization, and preparation of polyclonal antibodies

      ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
    45. Sabol, SZ; Hamer, DH
      An improved assay shows no association between the CYP2A6 gene and cigarette smoking behavior

      BEHAVIOR GENETICS
    46. GULLSTEN H; AGUNDEZ JAG; BENITEZ J; LAARA E; LADERO JM; DIAZRUBIO M; FERNANDEZSALGUERO P; GONZALEZ F; RAUTIO A; PELKONEN O; RAUNIO H
      CYP2A6 GENE POLYMORPHISM AND RISK OF LIVER-CANCER AND CIRRHOSIS

      Pharmacogenetics
    47. LI Y; LI NY; SELLERS EM
      COMPARISON OF CYP2A6 CATALYTIC ACTIVITY ON COUMARIN 7-HYDROXYLATION IN HUMAN AND MONKEY LIVER-MICROSOMES

      European journal of drug metabolism and pharmacokinetics
    48. DRAPER AJ; MADAN A; PARKINSON A
      INHIBITION OF COUMARIN 7-HYDROXYLASE ACTIVITY IN HUMAN LIVER-MICROSOMES

      Archives of biochemistry and biophysics
    49. WORMHOUDT LW; PLOEMEN JHTM; DEWAZIERS I; COMMANDEUR JNM; BEAUNE PH; VANBLADEREN PJ; VERMEULEN NPE
      INTERINDIVIDUAL VARIABILITY IN THE OXIDATION OF 1,2-DIBROMOETHANE - USE OF HETEROLOGOUSLY EXPRESSED HUMAN CYTOCHROME-P450 AND HUMAN LIVER-MICROSOMES

      Chemico-biological interactions
    50. NESNOW S; BECK S; ROSENBLUM S; LASLEY J; TIANO HF; HOSOKAWA M; CRESPI CL; LANGENBACH R
      N-NITROSODIETHYLAMINE AND 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE INDUCED MORPHOLOGICAL TRANSFORMATION OF C3H 10T1/2CL8 CELLS EXPRESSING HUMAN CYTOCHROME-P450 2A6/

      MUTATION RESEARCH
    51. SALONPAA P; HAKKOLA J; PASANEN M; PELKONEN O; VAHAKANGAS K; BATTULA N; NOUSO K; RAUNIO H
      RETROVIRUS-MEDIATED STABLE EXPRESSION OF HUMAN CYP2A6 IN MAMMALIAN-CELLS

      European journal of pharmacology. Environmental toxicology and pharmacology section


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Documento generato il 06/06/20 alle ore 07:58:04