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Effect of endotoxin on oleic acid lung injury does not depend on priming
JOURNAL OF APPLIED PHYSIOLOGY
Signal transduction in smooth muscle - Selected contribution: Synergism between TNF-alpha and IL-1 beta in airway smooth muscle cells: implications for beta-adrenergic responsiveness
JOURNAL OF APPLIED PHYSIOLOGY
Pathogenesis of NSAID-induced gastroduodenal mucosal injury
BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY
Nimesulide reduces interleukin-1 beta-induced cyclooxygenase-2 gene expression in human synovial fibroblasts
OSTEOARTHRITIS AND CARTILAGE
Effects of prostaglandin E-2 and cAMP elevating drugs on GM-CSF release bycultured human airway smooth muscle cells - Relevance to asthma therapy
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
Mechanisms of cytokine effects on G protein-coupled receptor-mediated signaling in airway smooth muscle
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
Detection of differentially expressed genes in human colon carcinoma cellstreated with a selective COX-2 inhibitor
ONCOGENE
Role of cyclooxygenase isoforms in gastric mucosal defence
JOURNAL OF PHYSIOLOGY-PARIS
The ever-emerging anti-inflammatories. Have there been any real advances?
JOURNAL OF PHYSIOLOGY-PARIS
Prostaglandin biology in inflammatory bowel disease
GASTROENTEROLOGY CLINICS OF NORTH AMERICA
Evidence for a direct role of cyclo-oxygenase 2 in implant wear debris-induced osteolysis
JOURNAL OF BONE AND MINERAL RESEARCH
Involvement of cyclooxygenase-derived prostaglandin E-2 and nitric oxide in the protection of rat pancreas afforded by low dose of lipopolysaccharide
JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
Measurement of cyclooxygenase isozyme inhibition in humans: exploring the clinical relevance of biochemical selectivity
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Introduction to "Nimesulide: Beyond COX-2"
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Complement C5b-9 induces cyclooxygenase-2 gene transcription in glomerularepithelial cells
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
Cyclo-oxygenase 2 tissue distribution and developmental pattern of expression in the chicken
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
Age-dependent changes in the regulation of cyclooxygenases in the gastrointestinal tract after gram-negative endotoxemia
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
Hyaluronan induced cyclooxygenase-2 expression promotes thromboxane A(2) production by renal cells
KIDNEY INTERNATIONAL
Sublingual meloxicam for renal colic
UROLOGIA INTERNATIONALIS
COX-2 expression in asthmatic airways: the story so far
THORAX
The potential of selective COX-2 inhibitors in inflammatory and other diseases
DRUGS OF TODAY
Role of cyclooxygenase-2 in gastric mucosal defense
LIFE SCIENCES
Sodium salicylate inhibits prostaglandin formation without affecting the induction of cyclooxygenase-2 by bacterial lipopolysaccharide in vivo
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
Expression of cyclo-oxygenase-2 in naturally occurring squamous cell carcinomas in dogs
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
Cyclooxygenase 2 - implications on maintenance of gastric mucosal integrity and ulcer healing: controversial issues and perspectives
GUT
Prostanoid production via COX-2 as a causative mechanism of rodent postoperative ileus
GASTROENTEROLOGY
Celecoxib, a selective cyclo-oxygenase-2 inhibitor reduces the severity ofexperimental colitis induced by dinitrobenzene sulfonic acid in rats
EUROPEAN JOURNAL OF PHARMACOLOGY
Cyclooxygenase selectivity of non-steroid anti-inflammatory drugs in humans: ex vivo evaluation
EUROPEAN JOURNAL OF PHARMACOLOGY
Dysidotronic acid, a new sesquiterpenoid, inhibits cytokine production andthe expression of nitric oxide synthase
EUROPEAN JOURNAL OF PHARMACOLOGY
Meloxicam inhibits rabbit ovulation
CONTRACEPTION
The human pharmacology of monocyte cyclooxygenase 2 inhibition by cortisoland synthetic glucocorticoids
CLINICAL PHARMACOLOGY & THERAPEUTICS
Effects of selective cyclooxygenase-2 inhibition on vascular responses andthrombosis in canine coronary arteries
CIRCULATION
Nitric oxide (NO) modulation of PAF-induced cardiopulmonary action: interaction between NO synthase and cyclo-oxygenase-2 pathways
BRITISH JOURNAL OF PHARMACOLOGY
Effects of S-2474, a novel nonsteroidal anti-inflammatory drug, on amyloidbeta protein-induced neuronal cell death
BRITISH JOURNAL OF PHARMACOLOGY
Modulation of haem oxygenase-1 expression by nitric oxide and leukotrienesin zymosan-activated macrophages
BRITISH JOURNAL OF PHARMACOLOGY
Ergolide, sesquiterpene lactone from Inula britannica, inhibits inducible nitric oxide synthase and cyclo-oxygenase-2 expression in RAW 264.7 macrophages through the inactivation of NF-kappa B
BRITISH JOURNAL OF PHARMACOLOGY
Effects of specific inhibition of cyclo-oxygenase-1 and cyclo-oxygenase-2 in the rat stomach with normal mucosa and after acid challenge
BRITISH JOURNAL OF PHARMACOLOGY
Disturbance of peristalsis in the guinea-pig isolated small intestine by indomethacin, but not cyclo-oxygenase isoform-selective inhibitors
BRITISH JOURNAL OF PHARMACOLOGY
Association between cyclo-oxygenase-2 overexpression and missense p53 mutations in gastric cancer
BRITISH JOURNAL OF CANCER
A histopathological study of the role of periodontal ligament tissue in root resorption in the rat
ARCHIVES OF ORAL BIOLOGY
TGF-beta 1 stimulates IL-8 release, COX-2 expression, and PGE(2) release in human airway smooth muscle cells
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
Regulation of cyclooxygenase-1 and-2 expression in human nasal mucosa. Effects of cytokines and dexamethasone
CLINICAL AND EXPERIMENTAL ALLERGY
Specific inhibitors of type 2 cyclooxygenase less renal effects than classical non steroidal anti-inflammatory agents?
NEPHROLOGIE
Effect of nabumetone treatment on vascular responses of the thoracic aortain rat experimental arthritis
PHARMACOLOGY
Co-regulation between cyclo-oxygenase-2 and inducible nitric oxide synthase expression in the time-course of murine inflammation
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
Induction of cyclooxygenase-2 by overexpression of the human catalase genein cerebral microvascular endothelial cells
JOURNAL OF NEUROCHEMISTRY
NSAID-induced gastric damage in rats: Requirement for inhibition of both cyclooxygenase 1 and 2
GASTROENTEROLOGY
Coordinate up- and down-regulation of glutathione-dependent prostaglandin E synthase and cyclooxygenase-2 in A549 cells - Inhibition by NS-398 and leukotriene C-4
EUROPEAN JOURNAL OF BIOCHEMISTRY
Effects of diclofenac, aceclofenac and meloxicam on the metabolism of proteoglycans and hyaluronan in osteoarthritic human cartilage
BRITISH JOURNAL OF PHARMACOLOGY
Vascular bed heterogeneity in age-related endothelial dysfunction with respect to NO and eicosanoids
BRITISH JOURNAL OF PHARMACOLOGY
Induction of COX-2 and PGE(2) biosynthesis by LL-1 beta is mediated by PKCand mitogen-activated protein kinases in murine astrocytes
BRITISH JOURNAL OF PHARMACOLOGY
Pharmacological evaluation of the role of cyclooxygenase isoenzymes on themicturition reflex following experimental cystitis in rats
BRITISH JOURNAL OF PHARMACOLOGY
Enhanced expression of haem oxygenase-1 by nitric oxide and antiinflammatory drugs in NIH 3T3 fibroblasts
BRITISH JOURNAL OF PHARMACOLOGY
Selective cyclo-oxygenase-2 inhibition with celecoxib elevates blood pressure and promotes leukocyte adherence
BRITISH JOURNAL OF PHARMACOLOGY
Release of GM-CSF and G-CSF by human arterial and venous smooth muscle cells: differential regulation by COX-2
BRITISH JOURNAL OF PHARMACOLOGY
Cyclooxygenase-2 expression in lipopolysaccharide-stimulated human monocytes is modulated by cyclic AMP, prostaglandin E-2, and nonsteroidal anti-inflammatory drugs
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Pathogenesis of non-steroidal anti-inflammatory drug gastropathy
ITALIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
Cyclo-oxygenase-2 in vascular smooth muscle (Review)
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
Cyclooxygenases in reproductive medicine and biology
JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION
Glucocorticoids ablate IL-1 beta-induced beta-adrenergic hyporesponsiveness in human airway smooth muscle cells
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
Eicosapentaenoic acid inhibits prostaglandin D-2 generation by inhibiting cyclo-oxygenase-2 in cultured human mast cells
CLINICAL AND EXPERIMENTAL ALLERGY
Inhibition of cyclo-oxygenase 2 expression in colon cells by the chemopreventive agent curcumin involves inhibition of NF-kappa B activation via the NIK/IKK signalling complex
ONCOGENE
Expression and localization of COX-2 in human airways and cultured airway epithelial cells
EUROPEAN RESPIRATORY JOURNAL
Constitutive expressions of type INOS in human airway smooth muscle cells:evidence for an antiproliferative role
FASEB JOURNAL
The epidemiology of nonsteroidal anti-inflammatory drugs
CANADIAN JOURNAL OF GASTROENTEROLOGY
A selective cyclo-oxygenase-2 inhibitor, NS-398, may improve portal hypertension without inducing gastric mucosal injury
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
Clinical use of etodolac for the treatment of lumbar disc herniation
CURRENT MEDICAL RESEARCH AND OPINION
Upregulation of vascular endothelial growth factor by cobalt chloride-simulated hypoxia is mediated by persistent induction of cyclooxygenase-2 in a metastatic human prostate cancer cell line
CLINICAL & EXPERIMENTAL METASTASIS
Interleukin-1 beta-induced hyperresponsiveness to [Sar(9),Met(O-2)(11)]substance P in isolated human bronchi
EUROPEAN JOURNAL OF PHARMACOLOGY
Selective cyclo-oxygenase-2 inhibitors aggravate ischaemia-reperfusion injury in the rat stomach
BRITISH JOURNAL OF PHARMACOLOGY
Cyclo-oxygenase-2: pharmacology, physiology, biochemistry and relevance toNSAID therapy
BRITISH JOURNAL OF PHARMACOLOGY
Ex vivo assay to determine the cyclooxygenase selectivity of non-steroidalanti-inflammatory drugs
BRITISH JOURNAL OF PHARMACOLOGY
Cyclo-oxygenase-2 mediates P2Y receptor-induced reactive astrogliosis
BRITISH JOURNAL OF PHARMACOLOGY
Involvement of tyrosine kinases on cyclooxygenase expression and prostaglandin E-2 production in human gingival fibroblasts stimulated with interleukin-1 beta and epidermal growth factor
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Glucocorticoid-mediated suppression of the promoter activity of the cyclooxygenase-2 gene is modulated by expression of its receptor in vascular endothelial cells
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DIFFERENTIAL INDUCTION OF CYCLOOXYGENASE-2 IN HUMAN ARTERIAL AND VENOUS SMOOTH-MUSCLE - ROLE OF ENDOGENOUS PROSTANOIDS
Arteriosclerosis, thrombosis, and vascular biology
CYCLOOXYGENASE-2 AS A THERAPEUTIC TARGET
Inflammation research
POSTTRANSLATIONAL REGULATION OF CYCLOOXYGENASE BY TYROSINE PHOSPHORYLATION IN CEREBRAL ENDOTHELIAL-CELLS
American journal of physiology. Cell physiology
ROLES FOR INTERLEUKIN-1-BETA, PHORBOL ESTER AND A POSTTRANSCRIPTIONALREGULATOR IN THE CONTROL OF BRADYKININ B1 RECEPTOR GENE-EXPRESSION
Biochemical journal
EXPRESSION AND VASCULAR EFFECTS OF CYCLOOXYGENASE-2 IN BRAIN
Stroke
DEXAMETHASONE PREVENTS THE INDUCTION OF COX-2 MESSENGER-RNA AND PROSTAGLANDINS IN THE LUMBAR SPINAL-CORD FOLLOWING INTRAPLANTAR FCA IN PARALLEL WITH INHIBITION OF EDEMA
Neuropharmacology
INDUCTION OF CYCLOOXYGENASE-2 AND ACTIVATION OF NUCLEAR FACTOR-KAPPA-B IN MYOCARDIUM OF PATIENTS WITH CONGESTIVE-HEART-FAILURE
Circulation
EFFECTS OF INHIBITION OF PROSTAGLANDIN ENDOPEROXIDE SYNTHASE-2 IN CHRONIC GASTROINTESTINAL ULCER MODELS IN RATS
British Journal of Pharmacology
SELECTIVE CYCLO-OXYGENASE-2 INHIBITORS AND THEIR INFLUENCE ON THE PROTECTIVE EFFECT OF A MILD IRRITANT IN THE RAT STOMACH
British Journal of Pharmacology
TRANSCRIPTIONAL ROLE OF THE NUCLEAR FACTOR KAPPA-B SITE IN THE INDUCTION BY LIPOPOLYSACCHARIDE AND SUPPRESSION BY DEXAMETHASONE OF CYCLOOXYGENASE-2 IN U937 CELLS
Biochemical and biophysical research communications
CARRAGEENAN-INDUCED HYPERALGESIA IS ASSOCIATED WITH INCREASED CYCLO-OXYGENASE-2 EXPRESSION IN SPINAL-CORD
NeuroReport
PROSTAGLANDIN-H SYNTHASE - PROTEIN SYNTHESIS-INDEPENDENT REGULATION IN BOVINE AORTIC ENDOTHELIAL-CELLS
American journal of physiology. Cell physiology
TUMOR-NECROSIS-FACTOR ENHANCES THE CAPSAICIN SENSITIVITY OF RAT SENSORY NEURONS
The Journal of neuroscience
DIFFERENTIAL REGULATION OF CYCLO-OXYGENASE-2 AND 5-LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) EXPRESSION BY GLUCOCORTICOIDS IN MONOCYTIC CELLS
British Journal of Pharmacology
EFFECT OF CALPAIN INHIBITOR-I, AN INHIBITOR OF THE PROTEOLYSIS OF I-KAPPA-B, ON THE CIRCULATORY FAILURE AND MULTIPLE ORGAN DYSFUNCTION CAUSED BY ENDOTOXIN IN THE RAT
British Journal of Pharmacology
NITRIC-OXIDE SYNTHASE AND CYCLOOXYGENASE PATHWAYS IN THE INFLAMMATORYRESPONSE INDUCED BY ZYMOSAN IN THE RAT AIR POUCH
British Journal of Pharmacology
INDUCTION OF CYCLO-OXYGENASE-2 BY CYTOKINES IN HUMAN CULTURED AIRWAY SMOOTH-MUSCLE CELLS - NOVEL INFLAMMATORY ROLE OF THIS CELL-TYPE
British Journal of Pharmacology
INDUCTION OF CYCLO-OXYGENASE-2 MESSENGER-RNA BY PROSTAGLANDIN E-2 IN HUMAN PROSTATIC-CARCINOMA CELLS
British Journal of Cancer
CYTOTOXICITY TO MACROPHAGES OF TETRANDRINE, AN ANTISILICOSIS ALKALOID, ACCOMPANIED BY AN OVERPRODUCTION OF PROSTAGLANDINS
Biochemical pharmacology
EVIDENCE FOR INVOLVEMENT OF NF-KAPPA-B IN THE TRANSCRIPTIONAL CONTROLOF COX-2 GENE-EXPRESSION BY IL-1-BETA
Biochemical and biophysical research communications
ALTERNATE COX-2 TRANSCRIPTS ARE DIFFERENTIALLY REGULATED - IMPLICATIONS FOR POSTTRANSCRIPTIONAL CONTROL
Biochemical and biophysical research communications
BUTYRATE, ASPIRIN AND COLORECTAL-CANCER
European journal of cancer prevention
NSAID GASTROPATHY - STATE-OF-THE-ART
The Italian Journal of Gastroenterology
CYTOKINE INDUCTION OF CYTOSOLIC PHOSPHOLIPASE A(2) AND CYCLOOXYGENASE-2 MESSENGER-RNA IS SUPPRESSED BY GLUCOCORTICOIDS IN HUMAN EPITHELIAL-CELLS
Life sciences
EXPRESSION OF CYCLOOXYGENASE-2 IN RAT-BRAIN FOLLOWING KAINATE TREATMENT
NeuroReport