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A decade of CDK5
NATURE REVIEWS MOLECULAR CELL BIOLOGY
ERK induces p35, a neuron-specific activator of Cdk5, through induction ofEgr1
NATURE CELL BIOLOGY
The presynaptic cytomatrix of brain synapses
CELLULAR AND MOLECULAR LIFE SCIENCES
Alteration of pRb expression in the development of rat tongue carcinoma induced by 4-nitroquinoline 1-oxide
ORAL ONCOLOGY
Expression of a Y-box protein, YB2/RYB-a, precedes protamine 2 expression during spermatogenesis in rodents
MOLECULAR HUMAN REPRODUCTION
When plant cells decide to divide
TRENDS IN PLANT SCIENCE
Apoptosis and cell growth inhibition as antitumor effector functions of interferons
MEDICAL ONCOLOGY
Cdk5 is involved in neuregulin-induced AChR expression at the neuromuscular junction
NATURE NEUROSCIENCE
Structure and regulation of the CDK5-p25(nck5a) complex
MOLECULAR CELL
A CDK-independent function of mammalian Cks1: Targeting of SCFSkp2 to the CDK inhibitor p27(Kip1)
MOLECULAR CELL
Control of RNA polymerase II activity by dedicated CTD kinases and phosphatases
FRONTIERS IN BIOSCIENCE
Xenopus phospho-CDK7/cyclin H expressed in baculoviral-infected insect cells
PROTEIN EXPRESSION AND PURIFICATION
Immunohistochemical analysis of p27 (Kip1) in human pituitary glands and in various types of pituitary adenomas
ENDOCRINE PATHOLOGY
Sporadic multiple primary melanoma cases: CDKN2A germline mutations with afounder effect
GENES CHROMOSOMES & CANCER
Cdk5 on the brain
CELL GROWTH & DIFFERENTIATION
Absence of mutations in the CDKN2 binding site of CDK4 in childhood acute lymphoblastic leukemia
LEUKEMIA & LYMPHOMA
Mechanisms of action of flavopiridol
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
Dynamic recruitment of Cdc2 to specific microtubule structures during mitosis
PLANT CELL
Regulation of thymidine kinase expression during cellular senescence
JOURNAL OF BIOMEDICAL SCIENCE
IFN alpha 2b induces apoptosis and proteasome-mediated degradation of p27(Kip1) in a human lung cancer cell line
ONCOLOGY REPORTS
Overexpression of SCC antigen and cyclins in an adenoid squamous carcinomacell line derived from the maxillary sinus
INTERNATIONAL JOURNAL OF ONCOLOGY
Isolation of a PSTAIRE CDC2 cDNA from Pinus contorta and its expression during adventitious root development
PLANT PHYSIOLOGY AND BIOCHEMISTRY
Coexpression of human cdk5 and its activator p35 with human protein tau inneurons in brain of triple transgenic mice
NEUROBIOLOGY OF DISEASE
Protein destruction: Adapting roles for Cks proteins
CURRENT BIOLOGY
Compartmentalized tau hyperphosphorylation and increased levels of kinasesin transgenic mice
NEUROREPORT
Region-specific expression of cell cycle inhibitors in the adult brain
NEUROREPORT
Suppression of arthritis by forced expression of cyclin-dependent kinase inhibitor p21(Cip1) gene into the joints
INTERNATIONAL IMMUNOLOGY
p35/cdk5 binds and phosphorylates beta-catenin and regulates beta-catenin/presenilin-1 interaction
EUROPEAN JOURNAL OF NEUROSCIENCE
Control of cell cycle progression in human mesothelioma cells treated withgamma interferon
ONCOGENE
Role of cyclin-dependent kinase inhibitors in the growth arrest at senescence in human prostate epithelial and uroepithelial cells
ONCOGENE
Proton pump inhibitors reduce cell cycle abnormalities in Barrett's esophagus
ONCOGENE
The retinoic acid receptor antagonist, BMS453, inhibits normal breast cellgrowth by inducing active TGF beta and causing cell cycle arrest
ONCOGENE
Common and reversible regulation of wild-type p53 function and of ribosomal biogenesis by protein kinases in human cells
ONCOGENE
Ectopic expression of Cdk6 circumvents transforming growth factor-beta mediated growth inhibition
ONCOGENE
E1A modulates phosphorylation of p130 and p107 by differentially regulating the activity of G1/S cyclin/CDK complexes
ONCOGENE
Anti-mitotic properties of indirubin-3'-monoxime, a CDK/GSK-3 inhibitor: induction of endoreplication following prophase arrest
ONCOGENE
Novel properties of the cyclin encoded by Human Herpesvirus 8 that facilitate exit from quiescence
ONCOGENE
Accumulation of high levels of the p53 and p130 growth-suppressing proteins in cell lines stably over-expressing cyclin-dependent kinase 6 (cdk6)
ONCOGENE
Cdk6-cyclin D3 complex evades inhibition by inhibitor proteins and uniquely controls cell's proliferation competence
ONCOGENE
Caspase-mediated Cdk2 activation is a critical step to execute transforming growth factor-beta 1-induced apoptosis in human gastric cancer cells
ONCOGENE
The protein kinase Pho85 is required for asymmetric accumulation of the Ash1 protein in Saccharomyces cerevisiae
MOLECULAR MICROBIOLOGY
New B-type cyclin synthesis is required between melosis I and II during Xenopus oocyte maturation
DEVELOPMENT
Dynamic temporal and spatial regulation of the cdk inhibitor p57(kip2) during embryo morphogenesis
MECHANISMS OF DEVELOPMENT
Cyclin-dependent kinase inhibitors, p21(waf1/cip1) and p27(kip1), are expressed site- and hair cycle-dependently in rat hair follicles
JOURNAL OF DERMATOLOGICAL SCIENCE
Identification of cylin-dependent kinase 1 inhibitors of a new chemical type by structure-based design and database searching
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
All-trans retinoic acid inhibits vascular smooth muscle cell proliferationtargeting multiple genes for cyclins and cyclin-dependent kinases.
Hypertension research
Detection of cell cycle-related factors in ameloblastomas
JOURNAL OF ORAL PATHOLOGY & MEDICINE
Inhibitory effect of glycolic acid on ultraviolet-induced skin tumorigenesis in SKH-1 hairless mice and its mechanism of action
MOLECULAR CARCINOGENESIS
Somatic INK4a-ARF locus mutations: A significant mechanism of gene inactivation in squamous cell carcinomas of the head and neck
MOLECULAR CARCINOGENESIS
Deregulation of Cdk5 in a mouse model of ALS: Toxicity alleviated by perikaryal neurofilament inclusions
NEURON
Inhibitory effects of 1 alpha,25-dihydroxyvitamin D-3 on the G(1)-S phase-controlling machinery
MOLECULAR ENDOCRINOLOGY
Comparison of the effects of recombinant adenovirus-mediated expression ofwildtype p53 and p27(Kip1) on cell cycle and apoptosis in SUDHL-1 cells derived from anaplastic large cell lymphoma
LEUKEMIA
Role of D-1 and E cyclins in cell cycle progression of human fibroblasts adhering to cementum attachment protein
JOURNAL OF BONE AND MINERAL RESEARCH
Folate supplementation inhibits intimal hyperplasia induced by a high-homocysteine diet in a rat carotid endarterectomy model
JOURNAL OF VASCULAR SURGERY
Disturbance of neuronal plasticity is a critical pathogenetic event in Alzheimer's disease
INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE
Protein p21(WAF1/CIP1) is phosphorylated by protein kinase CK2 in vitro and interacts with the amino terminal end of the CK2 beta subunit
JOURNAL OF CELLULAR BIOCHEMISTRY
Osteoclast differentiation is associated with transient upregulation of cyclin-dependent kinase inhibitors p21(WAF1/CIP1) and p27(KIP1)
JOURNAL OF CELLULAR BIOCHEMISTRY
The human melanocyte: a model system to study the complexity of cellular aging and transformation in non-fibroblastic cells
EXPERIMENTAL GERONTOLOGY
Transcriptional repression of p21(waf1) promoter by hepatitis B virus X protein via a p53-independent pathway
GENE
Human stem cell model to study signal transduction and molecular regulation mechanisms in CML
CHINESE MEDICAL JOURNAL
Neuronal cdc-2 like kinase in developing kindling rat hippocampus
CHINESE MEDICAL JOURNAL
Cells derived from tuberous sclerosis show a prolonged S phase of the cellcycle and increased apoptosis
ARCHIVES OF DERMATOLOGICAL RESEARCH
Alzheimer's disease as a disorder of mechanisms underlying structural brain self-organization
NEUROSCIENCE
Ethanol induced changes in cyclin-dependent kinase-5 activity and its activators, P35, P67 (Munc-18) in rat brain
NEUROSCIENCE LETTERS
Regulation of cell cycle molecules by the Ras effector system
MOLECULAR AND CELLULAR ENDOCRINOLOGY
Developmental mechanisms in the pathogenesis of neurodegenerative diseases
PROGRESS IN NEUROBIOLOGY
S and G(2) phase roles for Cdk2 revealed by inducible expression of a dominant-negative mutant in human cells
MOLECULAR AND CELLULAR BIOLOGY
Control of DNA rereplication via Cdc2 phosphorylation sites in the origin recognition complex
MOLECULAR AND CELLULAR BIOLOGY
The expression pattern of the cell cycle inhibitor p19(INK4d) by progenitor cells of the rat embryonic telencephalon and neonatal anterior subventricular zone
JOURNAL OF NEUROSCIENCE
Inhibition of cyclin E-cyclin-dependent kinase 2 complex formation and activity is associated with cell cycle arrest and withdrawal in oligodendrocyte progenitor cells
JOURNAL OF NEUROSCIENCE
Abnormal morphological and functional organization of the hippocampus in ap35 mutant model of cortical dysplasia associated with spontaneous seizures
JOURNAL OF NEUROSCIENCE
alpha 2-chimaerin, a Cdc42/Rac1 regulator, is selectively expressed in therat embryonic nervous system and is involved in neuritogenesis in N1E-115 neuroblastoma cells
JOURNAL OF NEUROSCIENCE
Cloning and functional expression of a degradation-resistant novel isoformof p27(Kip1)
BIOCHEMICAL JOURNAL
Wide spectrum of tumors in knock-in mice carrying a Cdk4 protein insensitive to INK4 inhibitors
EMBO JOURNAL
Cyclin A-CDK phosphorylates Sp1 and enhances Sp1-mediated transcription
EMBO JOURNAL
T-loop phosphorylation stabilizes the CDK7-cyclin H-MAT1 complex in vivo and regulates its CTD kinase activity
EMBO JOURNAL
The overexpression of cyclin-dependent kinase (CDK) 2 in laryngeal squamous cell carcinomas
ANTICANCER RESEARCH
Transient vs. prolonged histone hyperacetylation: effects on colon cancer cell growth, differentiation, and apoptosis
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
The molecular bases of Alzheimer's disease and other neurodegenerative disorders
ARCHIVES OF MEDICAL RESEARCH
p53 is dispensable for apoptosis but controls neurogenesis of mouse dentate gyrus cells following gamma-irradiation
MOLECULAR BRAIN RESEARCH
Molecular pathology of pituitary adenomas
JOURNAL OF NEURO-ONCOLOGY
Rb and E2F-1 regulate telomerase activity in human cancer cells
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION
The CRK3 protein kinase is essential for cell cycle progression of Leishmania Mexicana
MOLECULAR AND BIOCHEMICAL PARASITOLOGY
Role of the Reelin signaling pathway in central nervous system development
ANNUAL REVIEW OF NEUROSCIENCE
Neurodegenerative tauopathies
ANNUAL REVIEW OF NEUROSCIENCE
Expression and subcellular localization of the cyclin-dependent kinase inhibitor p27(Kip1) in epithelial ovarian cancer
GYNECOLOGIC ONCOLOGY
The role of p27 in endometrial carcinoma
GYNECOLOGIC ONCOLOGY
Positive effect of the induction of p21(WA1/CIP1) on the course of ischemic acute renal failure
KIDNEY INTERNATIONAL
Podocyte expression of the CDK-inhibitor p57 during development and disease
KIDNEY INTERNATIONAL
Glucocorticoids stimulate p21(CIP1) in mesangial cells and in anti-GBM glomerulonephritis
KIDNEY INTERNATIONAL
N-Ethylmaleimide sensitive factor [NSF] structure and function
INTERNATIONAL REVIEW OF CYTOLOGY - A SURVEY OF CELL BIOLOGY, VOL 207
Age-related accumulation of oxidative DNA damage and alterations in levelsof p16(INK4a/CDKN2a), p21(WAF1/CIP1/SDI1) and p27(KIP1) in human CD4+T cell clones in vitro
MECHANISMS OF AGEING AND DEVELOPMENT
Expression of cyclin E and cyclin-dependent kinase 2 correlates with metastasis and prognosis in colorectal carcinoma
HUMAN PATHOLOGY
p27: A potential main inhibitor of cell proliferation in digestive endocrine tumors but not a marker of benign behavior
HUMAN PATHOLOGY
A kinase to dampen the effects of cocaine?
SCIENCE
Cyclin/Cdk complexes: their involvement in cell cycle progression and mitotic division
PROTOPLASMA
Inclusion body myositis - Expression of extracellular signal-regulated kinase and its substrate
NEUROLOGY
Redundant control of rereplication in fission yeast
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Differential effects of p19(Arf) and p16(Ink4a) loss on senescence of murine bone marrow-derived preB cells and macrophages
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Cycline-dependent kinase inhibitor, p27 (KIP1), is associated with cholesteatoma
LARYNGOSCOPE