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La ricerca find articoli where soggetti phrase all words 'CYCLE CHECKPOINTS' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 194 riferimenti
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    1. Thompson, LH; Schild, D
      Homologous recombinational repair of DNA ensures mammalian chromosome stability

      MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
    2. Khanna, KK; Lavin, MF; Jackson, SP; Mulhern, TD
      ATM, a central controller of cellular responses to DNA damage

      CELL DEATH AND DIFFERENTIATION
    3. Shaw, MK; Roos, DS; Tilney, LG
      DNA replication and daughter cell budding are not tightly linked in the protozoan parasite Toxoplasma gondii

      MICROBES AND INFECTION
    4. Gasch, AP; Huang, MX; Metzner, S; Botstein, D; Elledge, SJ; Brown, PO
      Genomic expression responses to DNA-damaging agents and the regulatory role of the yeast ATR homolog Mec1p

      MOLECULAR BIOLOGY OF THE CELL
    5. Sarkaria, JN; Eshleman, JS
      ATM as a target for novel radiosensitizers

      SEMINARS IN RADIATION ONCOLOGY
    6. Gurley, KE; Kemp, CJ
      Synthetic lethality between mutation in Atm and DNA-PKcs during murine embryogenesis

      CURRENT BIOLOGY
    7. Durocher, D; Jackson, SP
      DNA-PK, ATM and ATR as sensors of DNA damage: variations on a theme?

      CURRENT OPINION IN CELL BIOLOGY
    8. Sablina, AA; Chumakov, PM; Levine, AJ; Kopnin, BP
      p53 activation in response to microtubule disruption is mediated by integrin-Erk signaling

      ONCOGENE
    9. Koniaras, K; Cuddihy, AR; Christopoulos, H; Hogg, A; O'Connell, MJ
      Inhibition of Chk1-dependent G2 DNA damage checkpoint radiosensitizes p53 mutant human cells

      ONCOGENE
    10. Yang, XL; Li, DM; Chen, WL; Xu, T
      Human homologue of Drosophila lats, LATS1, negatively regulate growth by inducing G(2)/M arrest or apoptosis

      ONCOGENE
    11. Bartkova, J; Falck, J; Rajpert-De Meyts, E; Skakkebaek, NE; Lukas, J; Bartek, J
      Chk2 tumour suppressor protein in human spermatogenesis and testicular germ-cell tumours

      ONCOGENE
    12. Falck, J; Lukas, C; Protopopova, M; Lukas, J; Selivanova, G; Bartek, J
      Functional impact of concomitant versus alternative defects in the Chk2-p53 tumour suppressor pathway

      ONCOGENE
    13. Gatei, M; Shkedy, D; Khanna, KK; Uziel, T; Shiloh, Y; Pandita, TK; Lavin, MF; Rotman, G
      Ataxia-telangiectasia: chronic activation of damage-responsive functions is reduced by alpha-lipoic acid

      ONCOGENE
    14. Norbury, CJ; Hickson, ID
      Cellular responses to DNA damage

      ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY
    15. Li, L; Story, M; Legerski, RJ
      Cellular responses to ionizing radiation damage

      INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
    16. Bishop, AJR; Schiestl, RH
      Homologous recombination as a mechanism of carcinogenesis

      BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
    17. Gottifredi, V; Karni-Schmidt, G; Shieh, SY; Prives, C
      p53 down-regulates CHK1 through p21 and the retinoblastoma protein

      MOLECULAR AND CELLULAR BIOLOGY
    18. Daniel, R; Katz, RA; Merkel, G; Hittle, JC; Yen, TJ; Skalka, AM
      Wortmannin potentiates integrase-mediated killing of lymphocytes and reduces the efficiency of stable transduction by retroviruses

      MOLECULAR AND CELLULAR BIOLOGY
    19. Bennett, CB; Snipe, JR; Westmoreland, JW; Resnick, MA
      SIR functions are required for the toleration of an unrepaired double-strand break in a dispensable yeast chromosome

      MOLECULAR AND CELLULAR BIOLOGY
    20. Buscemi, G; Savio, C; Zannini, L; Micciche, F; Masnada, D; Nakanishi, M; Tauchi, H; Komatsu, K; Mizutani, S; Khanna, K; Chen, P; Concannon, P; Chessa, L; Delia, D
      Chk2 activation dependence on Nbs1 after DNA damage

      MOLECULAR AND CELLULAR BIOLOGY
    21. Paciotti, V; Clerici, M; Scotti, M; Lucchini, G; Longhese, MP
      Characterization of mec1 kinase-deficient mutants and of new hypomorphic mec1 alleles impairing subsets of the DNA damage response pathway

      MOLECULAR AND CELLULAR BIOLOGY
    22. Xu, B; Kim, ST; Kastan, MB
      Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation

      MOLECULAR AND CELLULAR BIOLOGY
    23. Lanzi, C; Cassinelli, G; Cuccuru, G; Supino, R; Zuco, V; Ferlini, C; Scambia, G; Zunino, F
      Cell cycle checkpoint efficiency and cellular response to paclitaxel in prostate cancer cells

      PROSTATE
    24. Hofmann, WK; Miller, CW; Tsukasaki, K; Tavor, S; Ikezoe, T; Hoelzer, D; Takeuchi, S; Koeffler, HP
      Mutation analysis of the DNA-damage checkpoint gene CHK2 in myelodysplastic syndromes and acute myeloid leukemias

      LEUKEMIA RESEARCH
    25. Bullock, SK; Kaufmann, WK; Cordeiro-Stone, M
      Enhanced S phase delay and inhibition of replication of an undamaged shuttle vector in UVC-irradiated xeroderma pigmentosum variant

      CARCINOGENESIS
    26. Tarsounas, M; Moens, PB
      Checkpoint and DNA-repair proteins are associated with the cores of mammalian meiotic chromosomes

      CURRENT TOPICS IN DEVELOPMENTAL BIOLOGY, VOL 51
    27. Shiloh, Y; Kastan, MB
      ATM: Genome stability, neuronal development, and cancer cross paths

      ADVANCES IN CANCER RESEARCH, VOL 83
    28. Pelayo, HR; Lastres, P; De la Torre, C
      Replication and G(2) checkpoints: their response to caffeine

      PLANTA
    29. Hentges, KE; Sirry, B; Gingeras, AC; Sarbassov, D; Sonenberg, N; Sabatini, D; Peterson, AS
      FRAP/mTOR is required for proliferation and patterning during embryonic development in the mouse

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    30. Deming, PB; Cistulli, CA; Zhao, H; Graves, PR; Piwnica-Worms, H; Paules, RS; Downes, CS; Kaufmann, WK
      The human decatenation checkpoint

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    31. Lopez-Girona, A; Tanaka, K; Chen, XB; Baber, BA; McGowan, CH; Russell, P
      Serine-345 is required for Rad3-dependent phosphorylation and function of checkpoint kinase Chk1 in fission yeast

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    32. Randle, DH; Zindy, F; Sherr, CJ; Roussel, MF
      Differential effects of p19(Arf) and p16(Ink4a) loss on senescence of murine bone marrow-derived preB cells and macrophages

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    33. Nghiem, P; Park, PK; Kim, YS; Vaziri, C; Schreiber, SL
      ATR inhibition selectively sensitizes G(1) checkpoint-deficient cells to lethal premature chromatin condensation

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    34. Denning, G; Jamieson, L; Maquat, LE; Thompson, EA; Fields, AP
      Cloning of a novel phosphatidylinositol kinase-related kinase - Characterization of the human SMG-1 RNA surveillance protein

      JOURNAL OF BIOLOGICAL CHEMISTRY
    35. Curman, D; Cinel, B; Williams, DE; Rundle, N; Block, WD; Goodarzi, AA; Hutchins, JR; Clarke, PR; Zhou, BB; Lees-Miller, SP; Andersen, RJ; Roberge, M
      Inhibition of the G(2) DNA damage checkpoint and of protein kinases Chk1 and Chk2 by the marine sponge alkaloid debromohymenialdisine

      JOURNAL OF BIOLOGICAL CHEMISTRY
    36. Chen, MJ; Lin, YT; Lieberman, HB; Chen, G; Lee, EYHP
      ATM-dependent phosphorylation of human Rad9 is required for ionizing radiation-induced checkpoint activation

      JOURNAL OF BIOLOGICAL CHEMISTRY
    37. Deplanque, G; Ceraline, J; Mah-Becherel, MCM; Cazenave, JP; Bergerat, JP; Klein-Soyer, C
      Caffeine and the G2/M block override: A concept resulting from a misleading cell kinetic delay, independent of functional p53

      INTERNATIONAL JOURNAL OF CANCER
    38. Garcia-Perez, MA; Allende, LM; Corell, A; Varela, P; Moreno, AA; Sotoca, A; Moreno, A; Paz-Artal, E; Barreiro, E; Arnaiz-Villena, A
      Novel mutations and defective protein kinase C activation of T-lymphocytesin ataxia telangiectasia

      CLINICAL AND EXPERIMENTAL IMMUNOLOGY
    39. Zhao, H; Spitz, MR; Tomlinson, GE; Zhang, HF; Minna, JD; Wu, XF
      gamma-radiation-induced G(2) delay, apoptosis, and p53 response as potential susceptibility markers for lung cancer

      CANCER RESEARCH
    40. Kastan, MB; Lim, DS
      The many substrates and functions of ATM

      NATURE REVIEWS MOLECULAR CELL BIOLOGY
    41. Narayan, A; Tuck-Muller, C; Weissbecker, K; Smeets, D; Ehrlich, M
      Hypersensitivity to radiation-induced non-apoptotic and apoptotic death incell lines from patients with the ICF chromosome instability syndrome

      MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
    42. Borboa, L; De la Torre, C
      Adaptation to Cd(II) and Zn(II), and the caffeine-potentiated override of the G(2) block induced by the checkpoint activated by DNA damage

      PLANT BIOSYSTEMS
    43. Costanzo, V; Robertson, K; Ying, CY; Kim, E; Avvedimento, E; Gottesman, M; Grieco, D; Gautier, J
      Reconstitution of an ATM-dependent checkpoint that inhibits chromosomal DNA replication following DNA damage

      MOLECULAR CELL
    44. Guo, ZJ; Dunphy, WG
      Response of Xenopus Cds1 in cell-free extracts to DNA templates with double-stranded ends

      MOLECULAR BIOLOGY OF THE CELL
    45. Rehak, M; Csuka, I; Szepessy, E; Banfalvi, G
      Subphases of DNA replication in Drosophila cells

      DNA AND CELL BIOLOGY
    46. Chien, M; Rinker-Schaeffer, C; Stadler, WM
      A G2/M growth arrest response to low-dose intermittent H2O2 in normal uroepithelial cells

      INTERNATIONAL JOURNAL OF ONCOLOGY
    47. Jiang, XX; Lim, LY; Daly, JW; Li, AH; Jacobson, KA; Roberge, M
      Structure-activity relationships for G2 checkpoint inhibition by caffeine analogs

      INTERNATIONAL JOURNAL OF ONCOLOGY
    48. Hekmat-Nejad, M; You, ZS; Yee, MC; Newport, JW; Cimprich, KA
      Xenopus ATR is a replication-dependent chromatin-binding protein required for the DMA replication checkpoint

      CURRENT BIOLOGY
    49. Ohnishi, T; Komatsu, K; Tauchi, H; Wang, X; Takahashi, A; Ohnishi, K; Shiba, A; Matsumoto, H
      Brief Communication: Heat-induced accumulation of p53 and hsp72 is suppressed in lung fibroblasts from the SCID mouse

      INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
    50. Ababou, M; Dutertre, S; Lecluse, Y; Onclercq, R; Chatton, B; Amor-Gueret, M
      ATM-dependent phosphorylation and accumulation of endogenous BLM protein in response to ionizing radiation

      ONCOGENE
    51. Parker, GA; Touitou, R; Allday, MJ
      Epstein-Barr virus EBNA3C can disrupt multiple cell cycle checkpoints and induce nuclear division divorced from cytokinesis

      ONCOGENE
    52. Komatsu, K; Wharton, W; Hang, HY; Wu, C; Singh, S; Lieberman, HB; Pledger, WJ; Wang, HG
      PCNA interacts with hHus1/hRad9 in response to DNA damage and replication inhibition

      ONCOGENE
    53. Huyton, T; Bates, PA; Zhang, XD; Sternberg, MJE; Freemont, PS
      The BRCA1 C-terminal domain: structure and function

      MUTATION RESEARCH-DNA REPAIR
    54. Brown, EJ; Baltimore, D
      ATR disruption leads to chromosomal fragmentation and early embryonic lethality

      GENES & DEVELOPMENT
    55. Weiss, RS; Enoch, T; Leder, P
      Inactivation of mouse Hus1 results in genomic instability and impaired responses to genotoxic stress

      GENES & DEVELOPMENT
    56. Chan, TA; Hwang, PM; Hermeking, H; Kinzler, KW; Vogelstein, B
      Cooperative effects of genes controlling the G(2)/M checkpoint

      GENES & DEVELOPMENT
    57. Liu, QH; Guntuku, S; Cui, XS; Matsuoka, S; Cortez, D; Tamai, K; Luo, GB; Carattini-Rivera, S; DeMayo, F; Bradley, A; Donehower, LA; Elledge, SJ
      Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint

      GENES & DEVELOPMENT
    58. Garcia, V; Salanoubat, M; Choisne, N; Tissier, A
      An ATM homologue from Arabidopsis thaliana: complete genomic organisation and expression analysis

      NUCLEIC ACIDS RESEARCH
    59. Moser, BA; Brondello, JM; Baber-Furnari, B; Russell, P
      Mechanism of caffeine-induced checkpoint override in fission yeast

      MOLECULAR AND CELLULAR BIOLOGY
    60. Michelson, RJ; Weinert, T
      Closing the gaps among a web of DNA repair disorders

      BIOESSAYS
    61. Morrison, C; Sonoda, E; Takao, N; Shinohara, A; Yamamoto, K; Takeda, S
      The controlling role of ATM in homologous recombinational repair of DNA damage

      EMBO JOURNAL
    62. Tsuchiya, H; Mori, Y; Ueda, Y; Okada, G; Tomita, K
      Sensitization and caffeine potentiation of cisplatin cytotoxicity resulting from introduction of wild-type p53 gene in human osteosarcoma

      ANTICANCER RESEARCH
    63. Ollmann, M; Young, LM; Di Como, CJ; Karim, F; Belvin, M; Robertson, S; Whittaker, K; Demsky, M; Fisher, WW; Buchman, A; Duyk, G; Friedman, L; Prives, C; Kopczynski, C
      Drosophila p53 is a structural and functional homolog of the tumor suppressor p53

      CELL
    64. Weiss, RS; Leder, P; Enoch, T
      A conserved role for the Hus1 checkpoint protein in eukaryotic genome maintenance

      COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY
    65. Wu, X; Rathbun, G; Lane, WS; Weaver, DT; Livingston, DM
      Interactions of the Nijmegen breakage syndrome protein with ATM and BRCA1

      COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY
    66. Balczon, R
      Centrosome replication in somatic cells: The significance of G(1) phase

      CENTROSOME IN CELL REPLICATION AND EARLY DEVELOPMENT
    67. Zhou, BBS; Elledge, SJ
      The DNA damage response: putting checkpoints in perspective

      NATURE
    68. Matsuoka, S; Rotman, G; Ogawa, A; Shiloh, Y; Tamai, K; Elledge, SJ
      Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    69. Piers, E; Britton, R; Andersen, RJ
      Improved synthesis of isogranulatimide, a G2 checkpoint inhibitor. Syntheses of didemnimide C, isodidemnimide A, neodidemnimide A, 17-methylgranulatimide, and isogranulatimides A-C

      JOURNAL OF ORGANIC CHEMISTRY
    70. Yang, Q; Manicone, A; Coursen, JD; Linke, SP; Nagashima, M; Forgues, M; Wang, XW
      Identification of a functional domain in a GADD45-mediated G(2)/M checkpoint

      JOURNAL OF BIOLOGICAL CHEMISTRY
    71. Zhou, BBS; Chaturvedi, P; Spring, K; Scott, SP; Johanson, RA; Mishra, R; Mattern, MR; Winkler, JD; Khanna, KK
      Caffeine abolishes the mammalian G(2)/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity

      JOURNAL OF BIOLOGICAL CHEMISTRY
    72. Marsolier, MC; Roussel, P; Leroy, C; Mann, C
      Involvement of the PP2C-like phosphatase Ptc2p in the DNA checkpoint pathways of Saccharomyces cerevisiae

      GENETICS
    73. Gimenez-Abian, JF; Clarke, DJ; Devlin, J; Gimenez-Abian, MI; De la Torre, C; Johnson, RT; Mullinger, AM; Downes, CS
      Premitotic chromosome individualization in mammalian cells depends on topoisomerase II activity

      CHROMOSOMA
    74. Busby, EC; Leistritz, DF; Abraham, RT; Karnitz, LM; Sarkaria, JN
      The radiosensitizing agent 7-hydroxystaurosporine (UCN-01) inhibits the DNA damage checkpoint kinase hChk1

      CANCER RESEARCH
    75. Deplanque, G; Vincent, F; Mah-Becherel, MCM; Cazenave, JP; Bergerat, JP; Klein-Soyer, C
      Caffeine does not cause override of the G2/M block induced by UVc or gammaradiation in normal human skin fibroblasts

      BRITISH JOURNAL OF CANCER
    76. Josefsberg, LBY; Galiani, D; Dantes, A; Amsterdam, A; Dekel, N
      The proteasome is involved in the first metaphase-to-anaphase transition of meiosis in rat oocytes

      BIOLOGY OF REPRODUCTION
    77. Huang, SC; Huang, CYF; Lee, TC
      Induction of mitosis-mediated apoptosis by sodium arsenite in HeLaS3 cells

      BIOCHEMICAL PHARMACOLOGY
    78. Kitagawa, R; Rose, AM
      Components of the spindle-assembly checkpoint are essential in Caenorhabditis elegans

      NATURE CELL BIOLOGY
    79. Edwards, RJ; Bentley, NJ; Carr, AM
      A Rad3-Rad26 complex responds to DNA damage independently of other checkpoint proteins

      NATURE CELL BIOLOGY
    80. Takemura, T; Shinomiya, N; Rokutanda, M
      Role of G1 phase in the UV-induced apoptosis of EL-4 mouse lymphoma cells

      APOPTOSIS
    81. Raught, B; Gingras, AC
      eIF4E activity is regulated at multiple levels

      INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
    82. Uhrhammer, N; Fritz, E; Boyden, L; Meyn, MS
      Human fibroblasts transfected with an ATM antisense vector respond abnormally to ionizing radiation

      INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
    83. Kuruvilla, FG; Schreiber, SL
      The PIK-related kinases intercept conventional signaling pathways

      CHEMISTRY & BIOLOGY
    84. Chapman, CR; Evans, ST; Carr, AM; Enoch, T
      Requirement of sequences outside the conserved kinase domain of fission yeast Rad3p for checkpoint control

      MOLECULAR BIOLOGY OF THE CELL
    85. Fang, GW; Yu, HT; Kirschner, MW
      Control of mitotic transitions by the anaphase-promoting complex

      PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES
    86. Sibon, OCM; Laurencon, A; Hawley, RS; Theurkauf, WE
      The Drosophila ATM homologue Mei-41 has an essential checkpoint function at the midblastula transition

      CURRENT BIOLOGY
    87. Lavin, LF; Khanna, KK
      Review: ATM: the protein encoded by the gene mutated in the radiosensitivesyndrome ataxia-telangiectasia

      INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
    88. Carney, JP
      Chromosomal breakage syndromes

      CURRENT OPINION IN IMMUNOLOGY
    89. Takao, N; Kato, H; Mori, R; Morrison, C; Sonada, E; Sun, XG; Shimizu, H; Yoshioka, K; Takeda, S; Yamamoto, K
      Disruption of ATM in p53-null cells causes multiple functional abnormalities in cellular response to ionizing radiation

      ONCOGENE
    90. Hall-Jackson, CA; Cross, DAE; Morrice, N; Smythe, C
      ATR is a caffeine-sensitive, DNA-activated protein kinase with a substratespecificity distinct from DNA-PK

      ONCOGENE
    91. Rotman, G; Shiloh, Y
      ATM: A mediator of multiple responses to genotoxic stress

      ONCOGENE
    92. Lakin, ND; Hann, BC; Jackson, SP
      The ataxia-telangiectasia related protein ATR mediates DNA-dependent phosphorylation of p53

      ONCOGENE
    93. Zhan, QM; Antinore, MJ; Wang, XW; Carrier, F; Smith, ML; Harris, CC; Forance, AJ
      Association with Cdc2 and inhibition of Cdc2/cyclin B1 kinase activity by the p53-regulated protein Gadd45

      ONCOGENE
    94. Tibbetts, RS; Brumbaugh, KM; Williams, JM; Sarkaria, JN; Cliby, WA; Shieh, SY; Taya, Y; Prives, C; Abraham, RT
      A role for ATR in the DNA damage-induced phosphorylation of p53

      GENES & DEVELOPMENT
    95. Liao, MJ; Van Dyke, T
      Critical role for Atm in suppressing V(D)J recombination-driven thymic lymphoma

      GENES & DEVELOPMENT
    96. Rakovitch, E; Mellado, W; Hall, EJ; Pandita, TK; Sawant, S; Geard, CR
      Paclitaxel sensitivity correlates with p53 status and DNA fragmentation, but not G2/M accumulation

      INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
    97. von Deimling, F; Scharf, JM; Liehr, T; Rothe, M; Kelter, AR; Albers, P; Dietrich, WF; Kunkel, LOM; Wernert, N; Wirth, B
      Human and mouse RAD17 genes: identification, localization, genomic structure and histological expression pattern in normal testis and seminoma

      HUMAN GENETICS
    98. Passalaris, TM; Benanti, JA; Gewin, L; Kiyono, T; Galloway, DA
      The G(2) checkpoint is maintained by redundant pathways

      MOLECULAR AND CELLULAR BIOLOGY
    99. Pandita, TK; Westphal, CH; Anger, M; Sawant, SG; Geard, CR; Pandita, RK; Scherthan, H
      Atm inactivation results in aberrant telomere clustering during meiotic prophase

      MOLECULAR AND CELLULAR BIOLOGY
    100. Salisbury, JL; Whitehead, CM; Lingle, WL; Barrett, SL
      Centrosomes and cancer

      BIOLOGY OF THE CELL


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Documento generato il 22/10/20 alle ore 03:53:50