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Recent advances in feeding suppressing agents: potential therapeutic strategy for the treatment of obesity
EXPERT OPINION ON THERAPEUTIC PATENTS
Urocortin reduces oxygen consumption in lean and ob/ob mice
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
The role of corticotropin-releasing hormone receptors in placenta and fetal membranes during human pregnancy
MOLECULAR GENETICS AND METABOLISM
Synthesis and characterization of fluorinated and iodinated pyrrolopyrimidines as PET/SPECT ligands for the CRF1 receptor
NUCLEAR MEDICINE AND BIOLOGY
Functional and protein chemical characterization of the N-terminal domain of the rat corticotropin-releasing factor receptor 1
PROTEIN SCIENCE
Corticotrophin releasing hormone: its potential for a role in human myometrium
EXPERIMENTAL PHYSIOLOGY
Expression of corticotropin releasing factor (CRF), urocortin and CRF type1 receptors in hypothalamic-hypophyseal systems under osmotic stimulation
JOURNAL OF NEUROENDOCRINOLOGY
Physiological roles of corticotropin-releasing hormone receptor type 2
ENDOCRINE JOURNAL
Alternative splicing of CRH-R1 receptors in human and mouse skin: identification of new variants and their differential expression
FASEB JOURNAL
An oxidation resistant radioligand for corticotropin-releasing factor receptors
PEPTIDES
Corticotropin-releasing hormone and its receptors: an evaluation at the transcription level in vivo
PEPTIDES
Pharmacological characterization of recombinant rat corticotropin releasing factor binding protein using different sauvagine analogs
PEPTIDES
Chapter 3. New developments in the study of corticotropin releasing factor
ANNUAL REPORTS IN MEDICINAL CHEMISTRY, VOL 36
Pharmacological and chemical properties of astressin, antisauvagine-30 andalpha-helCRF: significance for behavioral experiments
NEUROPHARMACOLOGY
Cloning and functional pharmacology of two corticotropin-releasing factor receptors from a teleost fish
EUROPEAN JOURNAL OF PHARMACOLOGY
Suppression of food intake induced by corticotropin-releasing factor family in neonatal chicks
EUROPEAN JOURNAL OF PHARMACOLOGY
Corticotropin-releasing factor receptor type 1 mediates stress-induced relapse to cocaine-conditioned place preference in rats
EUROPEAN JOURNAL OF PHARMACOLOGY
Hypothalamic paraventricular nucleus injections of urocortin alter food intake and respiratory quotient
BRAIN RESEARCH
Antagonism of CRF2 receptors produces anxiolytic behavior in animal modelsof anxiety
BRAIN RESEARCH
Role of CRF receptor 1 in central CRF-induced stimulation of colonic propulsion in rats
BRAIN RESEARCH
Juxtamembrane region of the amino terminus of the corticotropin releasing factor receptor type 1 is important for ligand interaction
BIOCHEMISTRY
Localization and characterization of a short isoform of the corticotropin-releasing factor receptor type 2 alpha (CRF2 alpha-tr) in the rat brain
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
The discovery of 4-(3-pentylamino)-2,7-dimethyl-8-(2-methyl-4-methoxyphenyl)-pyrazolo-[1,5-alpha]-pyrimidine: A corticotropin-releasing factor (hCRF(1)) antagonist
BIOORGANIC & MEDICINAL CHEMISTRY
Sublethal hypoxia up-regulates corticotropin releasing factor receptor type I in fetal hippocampal neurons
NEUROREPORT
Vasopressin and oxytocin neurones of hypothalamic supraoptic and paraventricular nuclei co-express mRNA for type-1 andType-2 corticotropin-releasing hormone receptors
JOURNAL OF NEUROENDOCRINOLOGY
Differential roles of corticotropin-releasing factor receptor subtypes 1 and 2 in opiate withdrawal and in relapse to opiate dependence
EUROPEAN JOURNAL OF NEUROSCIENCE
Molecular integration of hypothalamo-pituitary-adrenal axis-related neurohormones on the GnRH neuron
BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE
The corticotropin-releasing hormone system in the regulation of energy balance in obesity
INTERNATIONAL JOURNAL OF OBESITY
Peripheral administration of CRF and urocortin: effects on food intake andthe HPA axis in the marsupial Sminthopsis crassicaudata
PEPTIDES
Urocortin and corticotropin-releasing factor receptor expression in the human colonic mucosa
PEPTIDES
The neurobiology of urocortin
REGULATORY PEPTIDES
Effects of prenatal stress on defensive withdrawal behavior and corticotropin releasing factor systems in rat brain
PHYSIOLOGY & BEHAVIOR
Evidence for the abundant expression of arginine 185 containing human CRF2alpha receptors and the role of position 185 for receptor-ligand selectivity
NEUROPHARMACOLOGY
Immunocytochemical distribution of corticotropin-releasing hormone receptor type-1 (CRF1)-like immunoreactivity in the mouse brain: Light microscopy analysis using an antibody directed against the C-terminus
JOURNAL OF COMPARATIVE NEUROLOGY
The role of CRF receptor subtypes in stress-induced behavioural responses
EUROPEAN JOURNAL OF PHARMACOLOGY
The role of afferents to the locus coeruleus in the handling stress-induced increase in the release of noradrenaline in the medial prefrontal cortex:a dual-probe microdialysis study in the rat brain
EUROPEAN JOURNAL OF PHARMACOLOGY
Novel high-affinity photoactivatable antagonists of corticotropin-releasing factor (CRF) - Photoaffinity labeling studies on CRF receptor, type 1 (CRFR1)
EUROPEAN JOURNAL OF BIOCHEMISTRY
Urocortin in the ventromedial hypothalamic nucleus acts as an inhibitor offeeding behavior in rats
BRAIN RESEARCH
Corticotropin-releasing factor antagonists, binding-protein and receptors:implications for central nervous system disorders
BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
Isolation and pharmacological characterization of two functional splice variants of corticotropin-releasing factor type 2 receptor from Tupaia belangeri
JOURNAL OF NEUROENDOCRINOLOGY
A novel spliced variant of the type 1 corticotropin-releasing hormone receptor with a deletion in the seventh transmembrane domain present in the human pregnant term myometrium and fetal membranes
MOLECULAR ENDOCRINOLOGY
Gene structural similarity between hCRF-R1 and glucagon receptor family
MOLECULAR MEDICINE: NOVEL FINDINGS OF GENE DIAGNOSIS, REGULATION OF GENE EXPRESSION, AND GENE THERAPY
ACTH-releasing activity and cAMP accumulation of rat urocortin-related peptides in pituitary corticotropic cells
BIOMEDICAL RESEARCH-TOKYO
Chronic treatment with the antidepressant amitriptyline decreases CRF-R1 receptor mRNA levels in the rat amygdala
NEUROSCIENCE LETTERS
A role for the bed nucleus of the stria terminalis, but not the amygdala, in the effects of corticotropin-releasing factor on stress-induced reinstatement of cocaine seeking
JOURNAL OF NEUROSCIENCE
Modulation of learning and anxiety by corticotropin-releasing factor (CRF)and stress: Differential roles of CRF receptors 1 and 2
JOURNAL OF NEUROSCIENCE
High-affinity binding of urocortin and astressin but not CRF to G protein-uncoupled CRFR1
PEPTIDES
Recent progress in corticotropin-releasing factor receptor agents
ANNUAL REPORTS IN MEDICINAL CHEMISTRY, VOL 34
Receptor binding, behavioral, and electrophysiological profiles of nonpeptide corticotropin-releasing factor subtype 1 receptor antagonists CRA1000 and CRA1001
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
Identification of amino acids in the N-terminal domain of corticotropin-releasing factor receptor 1 that are important determinants of high-affinity ligand binding
JOURNAL OF NEUROCHEMISTRY
Constrained corticotropin releasing factor antagonists (astressin analogues) with long duration of action in the rat
JOURNAL OF MEDICINAL CHEMISTRY
Expression and characterisation of human and rat CRF2 alpha receptors
EUROPEAN JOURNAL OF PHARMACOLOGY
Studies of the role of endothelium-dependent nitric oxide release in the sustained vasodilator effects of corticotrophin releasing factor and sauvagine
BRITISH JOURNAL OF PHARMACOLOGY
Reduced anxiety-like and cognitive performance in mice lacking the corticotropin-releasing factor receptor 1
BRAIN RESEARCH
7TM receptors: the splicing on the cake
TRENDS IN PHARMACOLOGICAL SCIENCES
Corticotropin-releasing factor antagonist attenuates the "anxiogenic-like"effect in the defensive burying paradigm but not in the elevated plus-mazefollowing chronic cocaine in rats
PSYCHOPHARMACOLOGY
STRESS-INDUCED CHANGES OF GENE-EXPRESSION IN THE PARAVENTRICULAR NUCLEUS ARE ENHANCED IN SPONTANEOUSLY HYPERTENSIVE RATS
Journal of neuroendocrinology
CORTICOTROPIN-RELEASING FACTOR-RECEPTOR 1-DEFICIENT MICE DISPLAY DECREASED ANXIETY, IMPAIRED STRESS-RESPONSE, AND ABERRANT NEUROENDOCRINE DEVELOPMENT
Neuron (Cambridge, Mass.)
THE GENOMIC ORGANIZATION OF THE HUMAN CORTICOTROPIN-RELEASING FACTOR TYPE-1 RECEPTOR
Gene
PHYSIOLOGICAL AND NEUROCHEMICAL ASPECTS OF CORTICOTROPIN-RELEASING FACTOR ACTIONS IN THE BRAIN - THE ROLE OF THE LOCUS-COERULEUS
Neurochemical research
STRUCTURE AND FUNCTION OF THE OVINE TYPE-1 CORTICOTROPIN-RELEASING FACTOR-RECEPTOR (CRF1) AND A CARBOXYL-TERMINAL VARIANT
Molecular and cellular endocrinology
SOLUBILIZATION AND BIOCHEMICAL-CHARACTERIZATION OF THE HUMAN MYOMETRIAL CORTICOTROPIN-RELEASING HORMONE-RECEPTOR
Molecular and cellular endocrinology
THE CORTICOTROPIN-RELEASING FACTOR-BINDING PROTEIN - AN ACT OF SEVERAL PARTS
Peptides (New York, N.Y. 1980)
EFFECT OF UROCORTIN AND ITS INTERACTION WITH ADRENOCORTICOTROPIN (ACTH) SECRETAGOGUES ON ACTH RELEASE
Peptides
EFFECTS OF LONG-TERM TREATMENT WITH CORTICOTROPIN-RELEASING FACTOR ONCORTICOTROPIC TUMOR-CELLS IN-VITRO
Regulatory peptides
DISTRIBUTION OF UROCORTIN-LIKE IMMUNOREACTIVITY IN THE CENTRAL-NERVOUS-SYSTEM OF THE RAT
Journal of comparative neurology
MUTATION AND EXPRESSION ANALYSIS OF CORTICOTROPIN-RELEASING FACTOR-1 RECEPTOR IN ADRENOCORTICOTROPIN-SECRETING PITUITARY-ADENOMAS
The Journal of clinical endocrinology and metabolism
MODULATION OF ENDOTHELIAL PROSTAGLANDIN SYNTHESIS BY CORTICOTROPIN-RELEASING FACTOR AND ANTAGONISTS
European journal of pharmacology
Corticotropin-releasing factor induces phosphorylation of phospholipase C-gamma at tyrosine residues via its receptor 2 beta in human epidermoid A-431 cells
EUROPEAN JOURNAL OF PHARMACOLOGY
CORTICOTROPIN-RELEASING FACTOR-RECEPTOR TYPE-1 FROM TUPAIA-BELANGERI - CLONING, FUNCTIONAL EXPRESSION AND TISSUE DISTRIBUTION
European journal of biochemistry
EFFECT OF UROCORTIN ON ACTH-SECRETION FROM RAT ANTERIOR-PITUITARY IN-VITRO AND IN-VIVO - COMPARISON WITH CORTICOTROPIN-RELEASING HORMONE
Brain research
CP-154,526, A SELECTIVE, NONPEPTIDE ANTAGONIST OF THE CORTISOTROPIN-RELEASING FACTOR(1) RECEPTOR ATTENUATES STRESS-INDUCED RELAPSE TO DRUG SEEKING IN COCAINE-TRAINED AND HEROIN-TRAINED RATS
Psychopharmacology
RAPID GENERATION OF STABLE CELL-LINES EXPRESSING CORTICOTROPIN-RELEASING HORMONE-RECEPTOR FOR DRUG DISCOVERY
Protein expression and purification
CORTICOTROPIN-RELEASING FACTOR RECEPTORS - AN OVERVIEW
EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
ALCOHOL INCREASES THE EXPRESSION OF TYPE-1, BUT NOT TYPE-2-ALPHA CORTICOTROPIN-RELEASING FACTOR(CRF) RECEPTOR MESSENGER-RIBONUCLEIC-ACID INTHE RAT HYPOTHALAMUS
Molecular brain research
DIFFERENTIAL REGULATION OF TYPE-1 AND TYPE-2-ALPHA CORTICOTROPIN-RELEASING HORMONE-RECEPTOR MESSENGER-RNA IN THE HYPOTHALAMIC PARAVENTRICULAR NUCLEUS OF THE RAT
Molecular brain research
DIFFERENTIAL REGULATION OF HYPOTHALAMIC-PITUITARY CORTICOTROPIN-RELEASING HORMONE RECEPTORS DURING DEVELOPMENT OF ADJUVANT-INDUCED ARTHRITIS IN THE RAT
Journal of Endocrinology
CORTICOTROPIN-RELEASING FACTOR-LIKE PEPTIDES INCREASE CYTOSOLIC [CA2-431 CELLS(] IN HUMAN EPIDERMOID A)
European journal of pharmacology
ENDOTOXIN DECREASES CORTICOTROPIN-RELEASING FACTOR-RECEPTOR-1 MESSENGER-RIBONUCLEIC-ACID LEVELS IN THE RAT PITUITARY
Endocrinology
BRAIN CORTICOTROPIN-RELEASING FACTOR IMMUNOREACTIVITY AND RECEPTORS IN 5 INBRED RAT STRAINS - RELATIONSHIP TO FORCED SWIMMING BEHAVIOR
Brain research
EXTRACELLULAR CYSTEINES OF THE CORTICOTROPIN-RELEASING FACTOR-RECEPTOR ARE CRITICAL FOR LIGAND INTERACTION
Biochemistry
AFFINITY PURIFICATION OF 61 AND 65-KDA RAT-BRAIN CORTICOTROPIN-RELEASING FACTOR RECEPTORS AND RECEPTOR-ASSOCIATED G-PROTEINS
International journal of biochemistry & cell biology
CRH-R1 MESSENGER-RNA EXPRESSION IN 2 STRAINS OF INBRED MICE AND ITS REGULATION AFTER REPEATED RESTRAINT STRESS
Molecular brain research
SYNTHESIS AND CHARACTERIZATION OF A PHOTOACTIVATABLE ANALOG OF CORTICOTROPIN-RELEASING FACTOR FOR SPECIFIC RECEPTOR LABELING
Proceedings of the National Academy of Sciences of the United Statesof America
A SINGLE-POINT SLIGHT ALTERATION SET AS A TOOL FOR STRUCTURE-ACTIVITYRELATIONSHIP STUDIES OF OVINE CORTICOTROPIN-RELEASING FACTOR
Journal of medicinal chemistry
STEADY-STATE METHADONE IN RATS DOES NOT CHANGE MESSENGER-RNA LEVELS OF CORTICOTROPIN-RELEASING FACTOR, ITS PITUITARY RECEPTOR OR PROOPIOMELANOCORTIN
European journal of pharmacology
THE HUMAN NEUROBLASTOMA CELL-LINE, IMR-32, EXPRESSES FUNCTIONAL CORTICOTROPIN-RELEASING FACTOR RECEPTORS
European journal of pharmacology
A NON PEPTIDIC CORTICOTROPIN-RELEASING FACTOR-RECEPTOR ANTAGONIST ATTENUATES FEVER AND EXHIBITS ANXIOLYTIC-LIKE ACTIVITY
European journal of pharmacology
[D-PRO(5)]CORTICOTROPIN-RELEASING FACTOR ANALOGS AS SELECTIVE AGONISTS AT CORTICOTROPIN-RELEASING FACTOR RECEPTORS
European journal of pharmacology
UROCORTIN, A CORTICOTROPIN-RELEASING FACTOR-RELATED MAMMALIAN PEPTIDE, INHIBITS EDEMA DUE TO THERMAL-INJURY IN RATS
European journal of pharmacology
IDENTIFICATION AND CHARACTERIZATION OF A CORTICOTROPIN-RELEASING HORMONE-RECEPTOR IN HUMAN PLACENTA
European journal of endocrinology
INCREASE OF EXTRACELLULAR CORTICOTROPIN-RELEASING FACTOR-LIKE IMMUNOREACTIVITY LEVELS IN THE AMYGDALA OF AWAKE RATS DURING RESTRAINT STRESSAND ETHANOL WITHDRAWAL AS MEASURED BY MICRODIALYSIS
The Journal of neuroscience
THE HUMAN MYOMETRIUM EXPRESSES MULTIPLE ISOFORMS OF THE CORTICOTROPIN-RELEASING HORMONE-RECEPTOR
The Journal of clinical endocrinology and metabolism
STRESS-SPECIFIC REGULATION OF CORTICOTROPIN-RELEASING HORMONE-RECEPTOR EXPRESSION IN THE PARAVENTRICULAR AND SUPRAOPTIC NUCLEI OF THE HYPOTHALAMUS IN THE RAT
Journal of neuroendocrinology
RECIPROCAL MODULATION OF CORTICOTROPIN-RELEASING FACTOR AND INTERLEUKIN-1 RECEPTORS FOLLOWING ETHER-LAPAROTOMY STRESS IN THE MOUSE
Brain research
STRUCTURE-RELATED EFFECTS OF CRF AND CRF-DERIVED PEPTIDES - DISSOCIATION OF BEHAVIORAL, ENDOCRINE AND AUTONOMIC ACTIVITY
Neuroendocrinology