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    1. Piganeau, G; Mouchiroud, D; Duret, L; Gautier, C
      Expected relationship between the silent substitution rate and the GC content: Implications for the evolution of isochores

      JOURNAL OF MOLECULAR EVOLUTION
    2. Myers, LP; Krieg, AM; Pruett, SB
      Bacterial DNA does not increase serum corticosterone concentration or prevent increases induced by other stimuli

      INTERNATIONAL IMMUNOPHARMACOLOGY
    3. Azuma, I; Seya, T
      Development of immunoadjuvants for immunotherapy of cancer

      INTERNATIONAL IMMUNOPHARMACOLOGY
    4. Liu, YJ; Kanzler, H; Soumelis, V; Gilliet, M
      Dendritic cell lineage, plasticity and cross-regulation

      NATURE IMMUNOLOGY
    5. Ohgane, J; Wakayama, T; Kogo, Y; Senda, S; Hattori, N; Tanaka, S; Yanagimachi, R; Shiota, K
      DNA methylation variation in cloned mice

      GENESIS
    6. Rudginsky, S; Siders, W; Ingram, L; Marshall, J; Scheule, R; Kaplan, J
      Antitumor activity of cationic lipid complexed with immunostimulatory DNA

      MOLECULAR THERAPY
    7. Uduehi, AN; Stammberger, U; Kubisa, B; Gugger, M; Buehler, TA; Schmid, RA
      Effects of linear polyethylenimine and polyethylenimine/DNA on lung function after airway instillation to rat lungs

      MOLECULAR THERAPY
    8. Tan, YD; Liu, F; Li, ZY; Li, S; Huang, L
      Sequential injection of cationic liposome and plasmid DNA effectively transfects the lung with minimal inflammatory toxicity

      MOLECULAR THERAPY
    9. Weiser, TS; Guo, ZS; Ohnmacht, GA; Parkhurst, ML; Tong-On, P; Marincola, FM; Fischette, MR; Yu, XD; Chen, GA; Hong, JA; Stewart, JH; Nguyen, DM; Rosenberg, SA; Schrump, DS
      Sequential 5-aza-2 '-deoxycytidine-depsipeptide FR901228 treatment inducesapoptosis preferentially in cancer cells and facilitates their recognitionby cytolytic T lymphocytes specific for NY-ESO-1

      JOURNAL OF IMMUNOTHERAPY
    10. Dai, ZY; Lakshmanan, RR; Zhu, WG; Smiraglia, DJ; Rush, LJ; Fruhwald, MC; Brena, RM; Li, B; Wright, FA; Ross, P; Otterson, GA; Plass, C
      Global methylation profiling of lung cancer identifies novel methylated genes

      NEOPLASIA
    11. Pisetsky, DS; Wenk, KS; Reich, CF
      The role of CpG sequences in the induction of anti-DNA antibodies

      CLINICAL IMMUNOLOGY
    12. Kaisho, T; Akira, S
      Dendritic-cell function in Toll-like receptor- and MyD88 knockout mice

      TRENDS IN IMMUNOLOGY
    13. Wohlleben, G; Erb, KJ
      Atopic disorders: a vaccine around the corner?

      TRENDS IN IMMUNOLOGY
    14. Masihi, KN
      Fighting infection using immunomodulatory agents

      EXPERT OPINION ON BIOLOGICAL THERAPY
    15. Eo, SK; Pack, C; Kumaraguru, U; Rouse, BT
      Optimisation of DNA vaccines for the prophylaxis and modulation of herpes simplex virus infections

      EXPERT OPINION ON BIOLOGICAL THERAPY
    16. Chelly, J; Mandel, JL
      Monogenic causes of X-linked mental retardation

      NATURE REVIEWS GENETICS
    17. Pennacchio, LA; Rubin, EM
      Genomic strategies to identify mammalian regulatory sequences

      NATURE REVIEWS GENETICS
    18. Lin, IG; Hsieh, CL
      Chromosomal DNA demethylation specified by protein binding

      EMBO REPORTS
    19. Liu, ZQ; Deng, GM; Foster, S; Tarkowski, A
      Staphylococcal peptidoglycans induce arthritis

      ARTHRITIS RESEARCH
    20. Deng, GM; Tarkowski, A
      Synovial cytokine mRNA expression during arthritis triggered by CpG motifsof bacterial DNA

      ARTHRITIS RESEARCH
    21. Maekawa, M; Sugano, K; Ushiama, M; Fukayama, N; Nomoto, K; Kashiwabara, H; Fujita, S; Kakizoe, T
      Heterogeneity of DNA methylation status analyzed by bisulfite-PCR-SSCP andcorrelation with clinico-pathological characteristics in colorectal cancer

      CLINICAL CHEMISTRY AND LABORATORY MEDICINE
    22. Inoue, J; Mitsuya, K; Maegawa, S; Kugoh, H; Kadota, M; Okamura, D; Shinohara, T; Nishihara, S; Takehara, S; Yamauchi, K; Schulz, TC; Oshimura, M
      Construction of 700 human/mouse A9 monochromosomal hybrids and analysis ofimprinted genes on human chromosome 6

      JOURNAL OF HUMAN GENETICS
    23. Bennett, CF
      Antisense therapy

      NEW DRUGS FOR ASTHMA, ALLERGY AND COPD
    24. Dobosy, JR; Selker, EU
      Emerging connections between DNA methylation and histone acetylation

      CELLULAR AND MOLECULAR LIFE SCIENCES
    25. Monroe, JJ; Manjanatha, RG; Skopek, TR
      Extent of CpG methylation is not proportional to the in vivo spontaneous mutation frequency at transgenic loci in Big Blue (TM) rodents

      MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
    26. Spack, EG; Sorgi, FL
      Developing non-viral DNA delivery systems for cancer and infectious disease

      DRUG DISCOVERY TODAY
    27. Takeda, K; Akira, S
      Roles of Toll-like receptors in innate immune responses

      GENES TO CELLS
    28. Kino, T; Takeshima, H; Nakao, M; Nishi, T; Yamamoto, K; Kimura, T; Saito, Y; Kochi, M; Kuratsu, J; Saya, H; Ushio, Y
      Identification of the cis-acting region in the NF2 gene promoter as a potential target for mutation and methylation-dependent silencing in schwannoma

      GENES TO CELLS
    29. Yang, X; Yan, L; Davidson, NE
      DNA methylation in breast cancer

      ENDOCRINE-RELATED CANCER
    30. Shahbazian, MD; Zoghbi, HY
      Molecular genetics of Rett syndrome and clinical spectrum of MECP2 mutations

      CURRENT OPINION IN NEUROLOGY
    31. Huehne, K; Rautenstrauss, B
      Transcriptional startpoints and methylation patterns in the PMP22 promoters of peripheral nerve, leukocytes and tumor cell lines

      INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
    32. Carter, AR; Segal, RA
      Rett syndrome model suggests MECP2 gives neurons the quiet they need to think

      NATURE NEUROSCIENCE
    33. Hagerman, RJ; Hagerman, PJ
      Fragile X syndrome: A model of gene-brain-behavior relationships

      MOLECULAR GENETICS AND METABOLISM
    34. Shahedian, B; Shi, YF; Zou, MJ; Farid, NR
      Thyroid carcinoma is characterized by genomic instability: Evidence from p53 mutations

      MOLECULAR GENETICS AND METABOLISM
    35. Szyf, M
      The role of DNA methyltransferase 1 in growth control

      FRONTIERS IN BIOSCIENCE
    36. Suzuki, Y; Tsunoda, T; Sese, J; Taira, H; Mizushima-Sugano, J; Hata, H; Ota, T; Isogai, T; Tanaka, T; Nakamura, Y; Suyama, A; Sakaki, Y; Morishita, S; Okubo, K; Sugano, S
      Identification and characterization of the potential promoter regions of 1031 kinds of human genes

      GENOME RESEARCH
    37. Charlier, C; Segers, K; Wagenaar, D; Karim, L; Berghams, S; Jaillon, O; Shay, T; Weissenbach, J; Cockett, N; Gyapay, G; Georges, M
      Human-ovine comparative sequencing of a 250-kb imprinted domain encompassing the callipyge (clpg) locus and identification of six imprinted transcripts: DLK1, DAT, GTL2, PEG11, antiPEG11, and MEG8

      GENOME RESEARCH
    38. Wu, Q; Zhang, T; Cheng, JF; Kim, Y; Grimwood, J; Schmutz, J; Dickson, M; Noonan, JP; Zhang, MQ; Myers, RM; Maniatis, T
      Comparative DNA sequence analysis of mouse and human protocadherin gene clusters

      GENOME RESEARCH
    39. Urnov, FD; Wolffe, AP
      Above and within the genome: Epigenetics past and present

      JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA
    40. Yan, L; Yang, XW; Davidson, NE
      Role of DNA methylation and histone acetylation in steroid receptor expression in breast cancer

      JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA
    41. Schlueter, AJ; Krieg, AM; De Vries, P; Li, X
      Type I interferon is the primary regulator of inducible Ly-6C expression on T cells

      JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
    42. Theise, ND; Krause, DS
      Suggestions for a new paradigm of cell differentiative potential

      BLOOD CELLS MOLECULES AND DISEASES
    43. Efferth, T; Futscher, BW; Osieka, R
      5-azacytidine modulates the response of sensitive and multidrug-resistant K562 leukemic cells to cytostatic drugs

      BLOOD CELLS MOLECULES AND DISEASES
    44. Cairns, P; Esteller, M; Herman, JG; Schoenberg, M; Jeronimo, C; Sanchez-Cespedes, M; Chow, NH; Grasso, M; Wu, L; Westra, WB; Sidransky, D
      Molecular detection of prostate cancer in urine by GSTP1 hypermethylation

      CLINICAL CANCER RESEARCH
    45. Dong, SM; Kim, HS; Rha, SH; Sidransky, D
      Promoter hypermethylation of multiple genes in carcinoma of the uterine cervix

      CLINICAL CANCER RESEARCH
    46. Virmani, AK; Muller, C; Rathi, A; Zoechbauer-Mueller, S; Mathis, M; Gazdar, AF
      Aberrant methylation during cervical carcinogenesis

      CLINICAL CANCER RESEARCH
    47. Matsumura, T; Makino, R; Mitamura, K
      Frequent down-regulation of E-cadherin by genetic and epigenetic changes in the malignant progression of hepatocellular carcinomas

      CLINICAL CANCER RESEARCH
    48. Wade, PA; Wolffe, AP
      ReCoGnizing methylated DNA

      NATURE STRUCTURAL BIOLOGY
    49. Kimchi, A
      A cell death-promoting kinase

      NATURE STRUCTURAL BIOLOGY
    50. Davuluri, RV; Grosse, I; Zhang, MQ
      Computational identification of promoters and first exons in the human genome

      NATURE GENETICS
    51. Kabbaj, M; Phillips, NC
      Anticancer activity of mycobacterial DNA: Effect of formulation as chitosan nanoparticles

      JOURNAL OF DRUG TARGETING
    52. Nicolao, P; Carella, M; Giometto, B; Tavolato, B; Cattin, R; Giovannucci-Uzielli, ML; Vacca, M; Della Regione, F; Piva, S; Bortoluzzi, S; Gasparini, P
      DHPLC analysis of the MECP2 gene in Italian Rett patients

      HUMAN MUTATION
    53. Santos, CB; Lima, MAC; Pimentel, MMG
      A new PCR assay useful for screening of FRAXE/FMR2 mental impairment amongmales

      HUMAN MUTATION
    54. Laccone, F; Huppke, P; Hanefeld, F; Meins, M
      Mutation spectrum in patients with Rett syndrome in the German population:Evidence of hot spot regions

      HUMAN MUTATION
    55. Jorgensen, JB; Zou, J; Johansen, A; Secombes, CJ
      Immunostimulatory CpG oligodeoxynucleotides stimulate expression of IL-1 beta and interferon-like cytokines in rainbow trout macrophages via a chloroquine-sensitive mechanism

      FISH & SHELLFISH IMMUNOLOGY
    56. Menigatti, M; Di Gregorio, C; Borghi, F; Sala, E; Scarselli, A; Pedroni, M; Foroni, M; Benatti, P; Roncucci, L; de Leon, MP; Percesepe, A
      Methylation pattern of different regions of the MLH1 promoter and silencing of gene expression in hereditary and sporadic colorectal cancer

      GENES CHROMOSOMES & CANCER
    57. Stetsenko, DA; Gait, MJ
      A convenient solid-phase method for synthesis of 3 '-conjugates of oligonucleotides

      BIOCONJUGATE CHEMISTRY
    58. Loisel, S; Le Gall, C; Doucet, L; Ferec, C; Floch, V
      Contribution of plasmid DNA to hepatotoxicity after systemic administration of lipoplexes

      HUMAN GENE THERAPY
    59. Calarota, SA; Kjerrstrom, A; Islam, KB; Wahren, B
      Gene combination raises broad human immunodeficiency virus-specific cytotoxicity

      HUMAN GENE THERAPY
    60. Decker, T; Peschel, C
      Effect of immunostimulatory CpG-oligonucleotides in chronic lymphocytic leukemia B cells

      LEUKEMIA & LYMPHOMA
    61. Bernauer, S; Wehling, M; Gerdes, D; Falkenstein, E
      The human membrane progesterone receptor gene: Genomic structure and promoter analysis

      DNA SEQUENCE
    62. McCluskie, MJ; Weeratna, RD; Payette, PJ; Davis, HL
      The potential of CpG oligodeoxynucleotides as mucosal adjuvants

      CRITICAL REVIEWS IN IMMUNOLOGY
    63. Wong, IHN
      Methylation profiling of human cancers in blood: Molecular monitoring and prognostication (Review)

      INTERNATIONAL JOURNAL OF ONCOLOGY
    64. Danam, RP; Howell, SR; Remack, JS; Brent, TP
      Heterogeneous methylation of the O-6-methylguanine-DNA methyltransferase promoter in immortalized IMR90 cell lines

      INTERNATIONAL JOURNAL OF ONCOLOGY
    65. Runte, M; Farber, C; Lich, C; Zeschnigk, M; Buchholz, T; Smith, A; Van Maldergem, L; Burger, J; Muscatelli, F; Gillessen-Kaesbach, G; Horsthemke, B; Buiting, K
      Comprehensive methylation analysis in typical and atypical PWS and AS patients with normal biparental chromosomes 15

      EUROPEAN JOURNAL OF HUMAN GENETICS
    66. Rosenberg, C; Wouters, CH; Szuhai, K; Dorland, R; Pearson, P; Poll-The, BT; Colombijn, RM; Bruning, M; Lindhout, D
      A Rett syndrome patient with a ring X chromosome: further evidence for skewing of X inactivation and heterogeneity in the aetiology of the disease

      EUROPEAN JOURNAL OF HUMAN GENETICS
    67. Nielsen, JB; Henriksen, KF; Hansen, C; Silahtaroglu, A; Schwartz, M; Tommerup, N
      MECP2 mutations in Danish patients with Rett syndrome: High frequency of mutations but no consistent correlations with clinical severity or with the X chromosome inactivation pattern

      EUROPEAN JOURNAL OF HUMAN GENETICS
    68. Girard, M; Couvert, P; Carrie, A; Tardieu, M; Chelly, J; Beldjord, C; Bienvenu, T
      Parental origin of de novo MECP2 mutations in Rett syndrome

      EUROPEAN JOURNAL OF HUMAN GENETICS
    69. Adel-Patient, K; Creminon, C; Boquet, D; Wal, JM; Chatel, JM
      Genetic immunisation with bovine beta-lactoglobulin cDNA induces a preventive and persistent inhibition of specific anti-BLG IgE response in mice

      INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
    70. Hochreiter, R; Hartl, A; Freund, J; Valenta, R; Ferreira, F; Thalhamer, J
      The influence of CpG motifs on a protein or DNA-based Th2-type immune response against major pollen allergens Bet v 1a, Phl p 2 and Escherichia coli-derived beta-galactosidase

      INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
    71. Alexander, JM
      Tumor suppressor loss in pituitary tumors

      BRAIN PATHOLOGY
    72. Li, GJ; Li, YJ; Yan, WY; Xu, QX; Wu, YQ; Xie, Y; You, YJ; Zheng, ZX
      CpG DNA enhances the immune responses elicited by the DNA vaccine against foot-and-mouth disease virus in guinea pigs

      CHINESE SCIENCE BULLETIN
    73. Akbarian, S; Chen, RZ; Gribnau, J; Rasmussen, TP; Fong, HF; Jaenisch, R; Jones, EG
      Expression pattern of the Rett syndrome gene MeCP2 in primate prefrontal cortex

      NEUROBIOLOGY OF DISEASE
    74. Colantuoni, C; Jeon, OH; Hyder, K; Chenchik, A; Khimani, AH; Narayanan, V; Hoffman, EP; Kaufmann, WE; Naidu, S; Pevsner, J
      Gene expression profiling in postmortem Rett syndrome brain: Differential gene expression and patient classification

      NEUROBIOLOGY OF DISEASE
    75. Gautam, A; Densmore, CL; Waldrep, JC
      Pulmonary cytokine responses associated with PEI-DNA aerosol gene therapy

      GENE THERAPY
    76. Gill, DR; Smyth, SE; Goddard, CA; Pringle, IA; Higgins, CF; Colledge, WH; Hyde, SC
      Increased persistence of lung gene expression using plasmids containing the ubiquitin C or elongation factor 1 alpha promoter

      GENE THERAPY
    77. McMahon, JM; Signori, E; Wells, KE; Fazio, VM; Wells, DJ
      Optimisation of electrotransfer of plasmid into skeletal muscle by pretreatment with hyaluronidase - increased expression with reduced muscle damage

      GENE THERAPY
    78. Chen, Y; Lenert, P; Weeratna, R; McCluskie, M; Wu, T; Davis, HL; Krieg, AM
      Identification of methylated CpG motifs as inhibitors of the immune stimulatory CpG motifs

      GENE THERAPY
    79. Hofman, CR; Dileo, JP; Li, Z; Li, S; Huang, L
      Efficient in Vivo gene transfer by PCR amplified fragment with reduced inflammatory activity

      GENE THERAPY
    80. Merlin, T; Gumenscheimer, M; Galanos, C; Freudenberg, MA
      TNF-alpha hyper-responses to Gram-negative and Gram-positive bacteria in Propionibacterium acnes primed or Salmonella typhimurium infected mice

      JOURNAL OF ENDOTOXIN RESEARCH
    81. Habermann, FA; Cremer, M; Walter, J; Kreth, G; von Hase, J; Bauer, K; Wienberg, J; Cremer, C; Cremer, T; Solovei, I
      Arrangements of macro- and microchromosomes in chicken cells

      CHROMOSOME RESEARCH
    82. Teranishi, M; Shimada, Y; Hori, T; Nakabayashi, O; Kikuchi, T; Macleod, T; Pym, R; Sheldon, B; Solovei, I; Macgregor, H; Mizuno, S
      Transcripts of the MHM region on the chicken Z chromosome accumulate as non-coding RNA in the nucleus of female cells adjacent to the DMRT1 locus

      CHROMOSOME RESEARCH
    83. Pao, MM; Tsutsumi, M; Liang, G; Uzvolgyi, E; Gonzales, FA; Jones, PA
      The endothelin receptor B (EDNRB) promoter displays heterogeneous, site specific methylation patterns in normal and tumor cells

      HUMAN MOLECULAR GENETICS
    84. Couvert, P; Bienvenu, T; Aquaviva, C; Poirier, K; Moraine, C; Gendrot, C; Verloes, A; Andres, C; Le Fevre, AC; Souville, I; Steffann, J; des Portes, V; Ropers, HH; Yntema, HG; Fryns, JP; Briault, S; Chelly, J; Cherif, B
      MECP2 is highly mutated in X-linked mental retardation

      HUMAN MOLECULAR GENETICS
    85. Baylin, SB; Esteller, M; Rountree, MR; Bachman, KE; Schuebel, K; Herman, JG
      Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer

      HUMAN MOLECULAR GENETICS
    86. Flint, J; Tufarelli, C; Peden, J; Clark, K; Daniels, RJ; Haudison, R; Miller, W; Philipsen, S; Tan-Un, KC; NcMorrow, T; Frampton, J; Alter, BP; Frischauf, AM; Higgs, DR
      Comparative genome analysis delimits a chromosomal domain and identifies key regulatory elements in the alpha globin cluster

      HUMAN MOLECULAR GENETICS
    87. John, RM; Ainscough, JFX; Barton, SC; Surani, MA
      Distant cis-elements regulate imprinted expression of the mouse p57(KiP2) (Cdkn1C) gene: implications for the human disorder, Beckwith-Wiedemann syndrome

      HUMAN MOLECULAR GENETICS
    88. Wan, MM; Zhao, KJ; Lee, SSJ; Francke, U
      MECP2 truncating mutations cause histone H4 hyperacetylation in Rett syndrome

      HUMAN MOLECULAR GENETICS
    89. Ellaway, CJ; Badawi, N; Raffaele, L; Christodoulou, J; Leonard, H
      A case of multiple congenital anomalies in association with Rett syndrome confirmed by MECP2 mutation screening

      CLINICAL DYSMORPHOLOGY
    90. Ashikawa, I
      Gene-associated CpG islands in plants as revealed by analyses of genomic sequences

      PLANT JOURNAL
    91. Takeshita, S; Takeshita, F; Haddad, DE; Janabi, N; Klinman, DM
      Activation of microglia and astrocytes by CpG oligodeoxynucleotides

      NEUROREPORT
    92. Porter, PL
      Molecular markers of tumor initiation and progression

      CURRENT OPINION IN GENETICS & DEVELOPMENT
    93. Smith, HA; Klinman, DM
      The regulation of DNA vaccines

      CURRENT OPINION IN BIOTECHNOLOGY
    94. Fearby, S; Frew, AJ
      Hunting the magic bullet in immunotherapy: new forms of old treatment or something completely different?

      CLINICAL AND EXPERIMENTAL ALLERGY
    95. Chen, YJ; Zhang, J; Moore, SA; Ballas, ZK; Portanova, JP; Krieg, AM; Berg, DJ
      CpG DNA induces cyclooxygenase-2 expression and prostaglandin production

      INTERNATIONAL IMMUNOLOGY
    96. Kerr, AM
      Recent developments in Rett syndrome research

      CURRENT OPINION IN PSYCHIATRY
    97. Labuhn, M; Jones, G; Speel, EJM; Maier, D; Zweifel, C; Gratzl, O; Van Meir, EG; Hegi, ME; Merlo, A
      Quantitative real-time PCR does not show selective targeting of p14(ARF) but concomitant inactivation of both p16(INK4A) and p14(ARF) in 105 human primary gliomas

      ONCOGENE
    98. Zhu, WG; Dai, ZY; Ding, HM; Srinivasan, K; Hall, J; Duan, WR; Villalona-Calero, MA; Plass, C; Otterson, GA
      Increased expression of unmethylated CDKN2D by 5-aza-2 '-deoxycytidine in human lung cancer cells

      ONCOGENE
    99. Takai, D; Yagi, Y; Wakazono, K; Ohishi, N; Morita, Y; Sugimura, T; Ushijima, T
      Silencing of HTR1B and reduced expression of EDN1 in human lung cancers, revealed by methylation-sensitive representational difference analysis

      ONCOGENE
    100. Atlas, E; Stramwasser, M; Mueller, CR
      A CREB site in the BRCA1 proximal promoter acts as a constitutive transcriptional element

      ONCOGENE


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Documento generato il 24/01/21 alle ore 08:13:51