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La ricerca find articoli where soggetti phrase all words 'COUMARIN 7-HYDROXYLATION' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 53 riferimenti
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    1. Hiratsuka, M; Mizugaki, M
      Genetic polymorphisms in drug-metabolizing enzymes and drug targets

      MOLECULAR GENETICS AND METABOLISM
    2. Oscarson, M
      Nicotine metabolism by the polymorphic cytochrome P450 2A6 (CYP2A6) enzyme: Implications for interindividual differences in smoking behaviour target article on nicotine-addiction

      PSYCOLOQUY
    3. Cok, I; Kocabas, NA; Cholerton, S; Karakaya, AE; Sardas, S
      Determination of coumarin metabolism in Turkish population

      HUMAN & EXPERIMENTAL TOXICOLOGY
    4. Kwon, JT; Nakajima, M; Chai, S; Yom, YK; Kim, HK; Yamazaki, H; Sohn, DR; Yamamoto, T; Kuroiwa, Y; Yokoi, T
      Nicotine metabolism and CYP2A6 allele frequencies in Koreans

      PHARMACOGENETICS
    5. Loriot, MA; Rebuissou, S; Oscarson, M; Cenee, S; Miyamoto, M; Ariyoshi, N; Kamataki, T; Hemon, D; Beaune, P; Stucker, I
      Genetic polymorphisms of cytochrome P450 2A6 in a case-control study on lung cancer in a French population

      PHARMACOGENETICS
    6. Paschke, T; Riefler, M; Schuler-Metz, A; Wolz, L; Scherer, G; McBride, CM; Bepler, G
      Comparison of cytochrome P450 2A6 polymorphism frequencies in Caucasians and African-Americans using a new one-step PCR-RFLP genotyping method

      TOXICOLOGY
    7. Zhang, WJ; Kilicarslan, T; Tyndale, RF; Sellers, EM
      Evaluation of methoxsalen, tranylcypromine, and tryptamine as specific andselective CYP2A6 inhibitors in vitro

      DRUG METABOLISM AND DISPOSITION
    8. Tyndale, RF; Sellers, EM
      Variable CYP2A6-mediated nicotine metabolism alters smoking behavior and risk

      DRUG METABOLISM AND DISPOSITION
    9. Oscarson, M
      Genetic polymorphisms in the cytochrome P450 2A6 (CYP2A6) gene: Implications for interindividual differences in nicotine metabolism

      DRUG METABOLISM AND DISPOSITION
    10. Sheng, JJ; Hua, ZC; Guo, JC; Caggana, M; Ding, XX
      Identification of a new human CYP2A gene fragment with close linkage to CYP2GP1

      DRUG METABOLISM AND DISPOSITION
    11. Kitagawa, K; Kunugita, N; Kitagawa, M; Kawamoto, T
      CYP2A6*6, a novel polymorphism in cytochrome P450 2A6, has a single amino acid substitution (R128Q) that inactivates enzymatic activity

      JOURNAL OF BIOLOGICAL CHEMISTRY
    12. Tan, W; Chen, GF; Xing, DY; Song, CY; Kadlubar, FF; Lin, DX
      Frequency of CYP2A6 gene deletion and its relation to risk of lung and esophageal cancer in the Chinese population

      INTERNATIONAL JOURNAL OF CANCER
    13. Nakajima, M; Kwon, JT; Tanaka, N; Zenta, T; Yamamoto, Y; Yamamoto, H; Yamazaki, H; Yamamoto, T; Kuroiwa, Y; Yokoi, T
      Relationship between interindividual differences in nicotine metabolism and CYP2A6 genetic polymorphism in humans

      CLINICAL PHARMACOLOGY & THERAPEUTICS
    14. Ariyoshi, N; Takahashi, Y; Miyamoto, M; Umetsu, Y; Daigo, S; Tateishi, T; Kobayashi, S; Mizorogi, Y; Loriot, MA; Stucker, I; Beaune, P; Kinoshita, M; Kamataki, T
      Structural characterization of a new variant of the CYP2A6 gene (CYP2A6*1B) apparently diagnosed as heterozygotes of CYP2A6*1A and CYP2A6*4C

      PHARMACOGENETICS
    15. Zabetian, CP; Gelernter, J; Cubells, JF
      Functional variants at CYP2A6: New genotyping methods, population genetics, and relevance to studies of tobacco dependence

      AMERICAN JOURNAL OF MEDICAL GENETICS
    16. Donato, MT; Viitala, P; Rodriguez-Antona, C; Lindfors, A; Castell, JV; Raunio, H; Gomez-Lechon, MJ; Pelkonen, O
      CYP2A5/CYP2A6 expression in mouse and human hepatocytes treated with various in vivo inducers

      DRUG METABOLISM AND DISPOSITION
    17. Rao, YS; Hoffmann, E; Zia, M; Bodin, L; Zeman, M; Sellers, EM; Tyndale, RF
      Duplications and defects in the CYP2A6 gene: Identification, genotyping, and in vivo effects on smoking

      MOLECULAR PHARMACOLOGY
    18. Nakajima, M; Yamagishi, S; Yamamoto, H; Yamamoto, T; Kuroiwa, Y; Yokoi, T
      Deficient cotinine formation from nicotine is attributed to the whole deletion of the CYP2A6 gene in humans

      CLINICAL PHARMACOLOGY & THERAPEUTICS
    19. Su, T; Bao, ZP; Zhang, QY; Smith, TJ; Hong, JY; Ding, XX
      Human cytochrome p450 CYP2A13: Predominant expression in the respiratory tract and its high efficiency metabolic activation of a tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone

      CANCER RESEARCH
    20. Mushiroda, T; Ariyoshi, N; Kimura, K; Takahara, E; Nagata, O; Kato, H; Kamataki, T
      A high-level expression of CYP2A in the lung of the suncus (Suncus murinus) and its role in the activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    21. Gu, DF; Hinks, LJ; Morton, NE; Day, INM
      The use of long PCR to confirm three common alleles at the CYP2A6 locus and the relationship between genotype and smoking habit

      ANNALS OF HUMAN GENETICS
    22. Kamataki, T; Nunoya, K; Sakai, Y; Kushida, H; Fujita, K
      Genetic polymorphism of CYP2A6 in relation to cancer

      MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
    23. Chen, GF; Tang, YM; Green, B; Lin, DX; Guengerich, FP; Daly, AK; Caporaso, NE; Kadlubar, FF
      Low frequency of CYP2A6 gene polymorphism as revealed by a one-step polymerase chain reaction method

      PHARMACOGENETICS
    24. Hong, JY; Wang, YY; Bondoc, FY; Lee, M; Yang, CS; Hu, WY; Pan, JM
      Metabolism of methyl tert-butyl ether and other gasoline ethers by human liver microsomes and heterologously expressed human cytochromes P450: Identification of CYP2A6 as a major catalyst

      TOXICOLOGY AND APPLIED PHARMACOLOGY
    25. Nunoya, K; Yokoi, T; Takahashi, Y; Kimura, K; Kinoshita, M; Kamataki, T
      Homologous unequal cross-over within the human CYP2A gene cluster as a mechanism for the deletion of the entire CYP2A6 gene associated with the poor metabolizer phenotype

      JOURNAL OF BIOCHEMISTRY
    26. Oscarson, M; McLellan, RA; Gullsten, H; Agundez, JAG; Benitez, J; Rautio, A; Raunio, H; Pelkonen, O; Ingelman-Sundberg, M
      Identification and characterisation of novel polymorphisms in the CYP2A locus: implications for nicotine metabolism

      FEBS LETTERS
    27. Oscarson, M; McLellan, RA; Gullsten, H; Yue, QY; Lang, MA; Bernal, ML; Sinues, B; Hirvonen, A; Raunio, H; Pelkonen, O; Ingelman-Sundberg, M
      Characterisation and PCR-based detection of a CYP2A6 gene deletion found at a high frequency in a Chinese population

      FEBS LETTERS
    28. Koskela, S; Hakkola, J; Hukkanen, J; Pelkonen, O; Sorri, M; Saranen, A; Anttila, S; Fernandez-Salguero, P; Gonzalez, F; Raunio, H
      Expression of CYP2A genes in human liver and extrahepatic tissues

      BIOCHEMICAL PHARMACOLOGY
    29. Kitagawa, K; Kunugita, N; Katoh, T; Yang, MH; Kawamoto, T
      The significance of the homozygous CYP2A6 deletion on nicotine metabolism:A new genotyping method of CYP2A6 using a single PCR-RFLP

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    30. Miyamoto, M; Umetsu, Y; Dosaka-Akita, H; Sawamura, Y; Yokota, J; Kunitoh, H; Nemoto, N; Sato, K; Ariyoshi, N; Kamataki, T
      CYP2A6 gene deletion reduces susceptibility to lung cancer

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    31. Soucek, P
      Expression of cytochrome P450 2A6 in Escherichia coli: Purification, spectral and catalytic characterization, and preparation of polyclonal antibodies

      ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
    32. Nelson, DR
      Cytochrome P450 and the individuality of species

      ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
    33. Sabol, SZ; Hamer, DH
      An improved assay shows no association between the CYP2A6 gene and cigarette smoking behavior

      BEHAVIOR GENETICS
    34. Ingelman-Sundberg, M; Oscarson, M; McLellan, RA
      Polymorphic human cytochrome P450 enzymes: an opportunity for individualized drug treatment

      TRENDS IN PHARMACOLOGICAL SCIENCES
    35. ADAMS TB; GREER DB; DOULL J; MUNRO IC; NEWBERNE P; PORTOGHESE PS; SMITH RL; WAGNER BM; WEIL CS; WOODS LA; FORD RA
      THE FEMA GRAS ASSESSMENT OF LACTONES USED AS FLAVOR INGREDIENTS

      Food and chemical toxicology
    36. DONATO MT; CASTELL JV; GOMEZLECHON MJ
      THE COUMARIN 7-HYDROXYLATION MICROASSAY IN LIVING HEPATIC CELLS IN CULTURE

      ATLA. Alternatives to laboratory animals
    37. HELLMOLD H; MAGNUSSON M; PELTOHUIKKO M; RYLANDER T; GUSTAFSSON JA; WARNER M
      IDENTIFICATION OF CYP2A3 AS A MAJOR CYTOCHROME-P450 ENZYME IN THE FEMALE PERIPUBERTAL RAT BREAST

      Molecular pharmacology
    38. OSCARSON M; GULLSTEN H; RAUTIO A; BERNAL ML; SINUES B; DAHL ML; STENGARD JH; PELKONEN O; RAUNIO H; INGELMANSUNDBERG M
      GENOTYPING OF HUMAN CYTOCHROME-P450 2A6 (CYP2A6), A NICOTINE C-OXIDASE

      FEBS letters
    39. GULLSTEN H; AGUNDEZ JAG; BENITEZ J; LAARA E; LADERO JM; DIAZRUBIO M; FERNANDEZSALGUERO P; GONZALEZ F; RAUTIO A; PELKONEN O; RAUNIO H
      CYP2A6 GENE POLYMORPHISM AND RISK OF LIVER-CANCER AND CIRRHOSIS

      Pharmacogenetics
    40. LANG DH; RETTIE AE; BOCKER RH
      IDENTIFICATION OF ENZYMES INVOLVED IN THE METABOLISM OF ATRAZINE, TERBUTHYLAZINE, AMETRYNE, AND TERBUTRYNE IN HUMAN LIVER-MICROSOMES

      Chemical research in toxicology
    41. LI Y; LI NY; SELLERS EM
      COMPARISON OF CYP2A6 CATALYTIC ACTIVITY ON COUMARIN 7-HYDROXYLATION IN HUMAN AND MONKEY LIVER-MICROSOMES

      European journal of drug metabolism and pharmacokinetics
    42. MESSINA ES; TYNDALE RF; SELLERS EM
      A MAJOR ROLE FOR CYP2A6 IN NICOTINE C-OXIDATION BY HUMAN LIVER-MICROSOMES

      The Journal of pharmacology and experimental therapeutics
    43. DRAPER AJ; MADAN A; PARKINSON A
      INHIBITION OF COUMARIN 7-HYDROXYLASE ACTIVITY IN HUMAN LIVER-MICROSOMES

      Archives of biochemistry and biophysics
    44. SATARUG S; LANG MA; YONGVANIT P; SITHITHAWORN P; MAIRIANG E; MAIRIANG P; PELKONEN P; BARTSCH H; HASWELLELKINS MR
      INDUCTION OF CYTOCHROME-P450 2A6 EXPRESSION IN HUMANS BY THE CARCINOGENIC PARASITE INFECTION, OPISTHORCHIASIS-VIVERRINI

      Cancer epidemiology, biomarkers & prevention
    45. KILLARD AJ; OKENNEDY R; BOGAN DP
      ANALYSIS OF THE GLUCURONIDATION OF 7-HYDROXYCOUMARIN BY HPLC

      Journal of pharmaceutical and biomedical analysis
    46. SU T; SHENG JJ; LIPINSKAS TW; DING XX
      EXPRESSION OF CYP2A GENES IN RODENT AND HUMAN NASAL-MUCOSA

      Drug metabolism and disposition
    47. NAKAJIMA M; YAMAMOTO T; NUNOYA K; YOKOI T; NAGASHIMA K; INOUE K; FUNAE Y; SHIMADA N; KAMATAKI T; KUROIWA Y
      ROLE OF HUMAN CYTOCHROME P4502A6 IN C-OXIDATION OF NICOTINE

      Drug metabolism and disposition
    48. RAUMA AL; RAUTIO A; PASANEN M; PELKONEN O; TORRONEN R; MYKKANEN H
      COUMARIN 7-HYDROXYLATION IN LONG-TERM ADHERENTS OF A STRICT UNCOOKED VEGAN DIET

      European Journal of Clinical Pharmacology
    49. LIU C; ZHUO XL; GONZALEZ FJ; DING XX
      BACULOVIRUS-MEDIATED EXPRESSION AND CHARACTERIZATION OF RAT CYP2A3 AND HUMAN CYP2A6 - ROLE IN METABOLIC-ACTIVATION OF NASAL TOXICANTS

      Molecular pharmacology
    50. NUNOYA KI; YOKOI T; KIMURA K; KODAMA T; FUNAYAMA M; INOUE K; NAGASHIMA K; FUNAE Y; SHIMADA N; GREEN C; KAMATAKI T
      (-CIS-3,5-DIMETHYL-2-(3-PYRIDYL) THIAZOLIDIN-4-ONE HYDROCHLORIDE (SM-12502) AS A NOVEL SUBSTRATE FOR CYTOCHROME-P450 2A6 IN HUMAN LIVER-MICROSOMES())

      The Journal of pharmacology and experimental therapeutics
    51. BEREZIAT JC; RAFFALLI F; SCHMEZER P; FREI E; GENESTE O; LANG MA
      CYTOCHROME-P450 2A OF NASAL EPITHELIUM - REGULATION AND ROLE IN CARCINOGEN METABOLISM

      Molecular carcinogenesis
    52. KHARASCH ED; HANKINS DC; THUMMEL KE
      HUMAN KIDNEY METHOXYFLURANE AND SEVOFLURANE METABOLISM - INTRARENAL FLUORIDE PRODUCTION AS A POSSIBLE MECHANISM OF METHOXYFLURANE NEPHROTOXICITY

      Anesthesiology
    53. ISCAN M; ROSTAMI H; ISCAN M; GURAY T; PELKONEN O; RAUTIO A
      INTERINDIVIDUAL VARIABILITY OF COUMARIN 7-HYDROXYLATION IN A TURKISH POPULATION

      European Journal of Clinical Pharmacology


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Documento generato il 03/08/20 alle ore 19:37:21