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Pharmacologic therapy in traumatic brain injury: Update on experimental treatment strategies
CURRENT PHARMACEUTICAL DESIGN
Role of cerebral inflammation after traumatic brain injury: A revisited concept
SHOCK
Methodology of brain perfusion imaging
JOURNAL OF MAGNETIC RESONANCE IMAGING
Antisense knockdown of the glial glutamate transporter GLT-1 exacerbates hippocampal neuronal damage following traumatic injury to rat brain
EUROPEAN JOURNAL OF NEUROSCIENCE
Intraarterial administration of marrow stromal cells in a rat model of traumatic brain injury
JOURNAL OF NEUROTRAUMA
Free radical scavenger posttreatment improves functional and morphologicaloutcome after fluid percussion injury in the rat
JOURNAL OF NEUROTRAUMA
Detection of single- and double-strand DNA breaks after traumatic brain injury in rats: Comparison of in situ labeling techniques using DNA polymerase 1, the Klenow fragment of DNA polymerase 1, and terminal deoxynucleotidyltransferase
JOURNAL OF NEUROTRAUMA
The simple model versus the super model: Translating experimental traumatic brain injury research to the bedside
JOURNAL OF NEUROTRAUMA
Adenovirus-mediated transfer and expression of beta-Gal in injured hippocampus after traumatic brain injury in mice
JOURNAL OF NEUROTRAUMA
Early expression of glutamate transporter proteins in ramified microglia after controlled cortical impact injury in the rat
GLIA
Perfusion imaging using dynamic arterial spin labeling (DASL)
MAGNETIC RESONANCE IN MEDICINE
Assessment of the effect of 2-chloroadenosine in normal rat brain using spin-labeled MRI measurement of perfusion
MAGNETIC RESONANCE IN MEDICINE
TUNEL-positive staining in white and grey matter after fatal head injury in man
CLINICAL NEUROPATHOLOGY
Upregulation of ICAM-1 and MCP-1 but not of MIP-2 and sensorimotor deficitin response to traumatic axonal injury in rats
JOURNAL OF NEUROSCIENCE RESEARCH
The selective 5-HT1a receptor agonist repinotan HCL attenuates histopathology and spatial learning deficits following traumatic brain injury in rats
NEUROSCIENCE
Delayed hemorrhagic hypotension exacerbates the hemodynamic and histopathologic consequences of traumatic brain injury in rats
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
Effects of moderate hypothermia on IL-1 beta-induced leukocyte rolling andadhesion in pial microcirculation of mice and on proinflammatory gene expression in human cerebral endothelial cells
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
Cognitive deficits following blast injury-induced neurotrauma: possible involvement of nitric oxide
BRAIN INJURY
Applications of the Morris water maze in the study of learning and memory
BRAIN RESEARCH REVIEWS
Impaired motor learning and diffuse axonal damage in motor and visual systems of the rat following traumatic brain injury
NEUROLOGICAL RESEARCH
Posttraumatic hypothermia is neuroprotective in a model of traumatic braininjury complicated by a secondary hypoxic insult
CRITICAL CARE MEDICINE
Cerebral resuscitation after traumatic brain injury and cardiopulmonary arrest in infants and children in the new millennium
PEDIATRIC CLINICS OF NORTH AMERICA
Treatment window for hypothermia in brain injury
JOURNAL OF NEUROSURGERY
Mild head injury increasing the brain's vulnerability to a second concussive impact
JOURNAL OF NEUROSURGERY
Protective effects of glial cell line-derived neurotrophic factor on hippocampal neurons after traumatic brain injury in rats
JOURNAL OF NEUROSURGERY
Intracranial bone marrow transplantation after traumatic brain injury improving functional outcome in adult rats
JOURNAL OF NEUROSURGERY
In situ DNA fragmentation occurs in white matter up to 12 months after head injury in man
ACTA NEUROPATHOLOGICA
Cognitive and histopathological outcome after weight-drop brain injury in the rat: influence of systemic administration of monoclonal antibodies to ICAM-1
ACTA NEUROPATHOLOGICA
Secondary hypoxemia exacerbates the reduction of visual discrimination accuracy and neuronal cell density in the dorsal lateral geniculate nucleus resulting from fluid percussion injury
JOURNAL OF NEUROTRAUMA
Long-term dysfunction following diffuse traumatic brain injury in the immature rat
JOURNAL OF NEUROTRAUMA
Cognitive impairment and synaptosomal choline uptake in rats following impact acceleration injury
JOURNAL OF NEUROTRAUMA
Recovery of water maze performance in aged versus young rats after brain injury with the impact acceleration model
JOURNAL OF NEUROTRAUMA
Isoflurane improves long-term neurologic outcome versus fentanyl after traumatic brain injury in rats
JOURNAL OF NEUROTRAUMA
Traumatic brain injury reduces hippocampal alpha 7 nicotinic cholinergic receptor binding
JOURNAL OF NEUROTRAUMA
Regional expression and role of cyclooxygenase-2 following experimental traumatic brain injury
JOURNAL OF NEUROTRAUMA
Application of 2,3,5-triphenyltetrazolium chloride staining to evaluate injury volume after controlled cortical impact brain injury: Role of brain edema in evolution of injury volume
JOURNAL OF NEUROTRAUMA
Reduced brain edema after traumatic brain injury in mice deficient in P-selectin and intercellular adhesion molecule-1
JOURNAL OF LEUKOCYTE BIOLOGY
Presynaptic excitability changes following traumatic brain injury in the rat
JOURNAL OF NEUROSCIENCE RESEARCH
Induced hypothermia in experimental pneumococcal meningitis
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
Importance of posttraumatic hypothermia and hyperthermia on the inflammatory response after fluid percussion brain injury: Biochemical and immunocytochemical studies
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
Effects of matrix metalloproteinase-9 gene knock-out on morphological and motor outcomes after traumatic brain injury
JOURNAL OF NEUROSCIENCE
Local neutrophil influx following lateral fluid-percussion brain injury inrats is associated with accumulation of complement activation fragments ofthe third component (C3) of the complement system
JOURNAL OF NEUROIMMUNOLOGY
No long-term benefit from hypothermia after severe traumatic brain injury with secondary insult in rats
CRITICAL CARE MEDICINE
Effects of dopamine on posttraumatic cerebral blood flow, brain edema, andcerebrospinal fluid glutamate and hypoxanthine concentrations
CRITICAL CARE MEDICINE
Effect of neutropenia and granulocyte colony stimulating factor-induced neutrophilia on blood-brain barrier permeability and brain edema after traumatic brain injury in rats
CRITICAL CARE MEDICINE
Effects of subdural haematoma on sensorimotor functioning and spatial learning in rats
NEUROPHARMACOLOGY
Effect of long-term mild hypothermia therapy in patients with severe traumatic brain injury: 1-year follow-up review of 87 cases
JOURNAL OF NEUROSURGERY
Caspase-3 mediated neuronal death after traumatic brain injury in rats
JOURNAL OF NEUROCHEMISTRY
NPS 1506 attenuates cognitive dysfunction and hippocampal neuron death following brain trauma in the rat
EXPERIMENTAL NEUROLOGY
Brain trauma in aged transgenic mice induces regression of established A beta deposits
EXPERIMENTAL NEUROLOGY
Evaluation of combined fibroblast growth factor-2 and moderate hypothermiatherapy in traumatically brain injured rats
BRAIN RESEARCH
Increased cerebrospinal fluid glutamate and taurine concentrations are associated with traumatic brain edema formation in rats
BRAIN RESEARCH
Experimental models of brain trauma
CURRENT OPINION IN NEUROLOGY
The consequences of traumatic brain injury on cerebral blood flow and autoregulation: A review
CLINICAL AND EXPERIMENTAL HYPERTENSION
Differential effects of traumatic brain injury on vesicular acetylcholine transporter and M-2 muscarinic receptor mRNA and protein in rat
JOURNAL OF NEUROTRAUMA
Lubeluzole following traumatic brain injury in the rat
JOURNAL OF NEUROTRAUMA
Behavioral responses of C57BL/6, FVB/N, and 129/SvEMS mouse strains to traumatic brain injury: Implications for gene targeting approaches to neurotrauma
JOURNAL OF NEUROTRAUMA
Effect of traumatic brain injury in mice deficient in intercellular adhesion molecule-1: Assessment of histopathologic and functional outcome
JOURNAL OF NEUROTRAUMA
Effects of six weeks of chronic ethanol administration on the behavioral outcome of rats after lateral fluid percussion brain injury
JOURNAL OF NEUROTRAUMA
Time course for recovery of water maze performance and central cholinergicinnervation after fluid percussion injury
JOURNAL OF NEUROTRAUMA
Prolonged activation of NF-kappa B following traumatic brain injury in rats
JOURNAL OF NEUROTRAUMA
Secondary hypoxia following moderate fluid percussion brain injury in ratsexacerbates sensorimotor and cognitive deficits
JOURNAL OF NEUROTRAUMA
Validation of a controlled cortical impact model of head injury in mice
JOURNAL OF NEUROTRAUMA
P-selectin blockade following fluid-percussion injury: Behavioral and immunochemical sequelae
JOURNAL OF NEUROTRAUMA
Reduction of cognitive and motor deficits after traumatic brain injury in mice deficient in poly(ADP-ribose) polymerase
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
The impact-acceleration model of head injury: Injury severity predicts motor and cognitive performance after trauma
NEUROLOGICAL RESEARCH
Simple and reproducible model of rat spinal cord injury induced by a controlled cortical impact device
NEUROLOGICAL RESEARCH
Differential acute and chronic responses of tumor necrosis factor-deficient mice to experimental brain injury
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Effect of cerebral perfusion pressure on contusion volume following impactinjury
JOURNAL OF NEUROSURGERY
Overexpression of Bcl-2 is neuroprotective after experimental brain injuryin transgenic mice
JOURNAL OF COMPARATIVE NEUROLOGY
Inducible nitric oxide synthase is an endogenous neuroprotectant after traumatic brain injury in rats and mice
JOURNAL OF CLINICAL INVESTIGATION
Genetic approaches to neurotrauma research: Opportunities and potential pitfalls of murine models
EXPERIMENTAL NEUROLOGY
HYPERGLYCEMIA INCREASES NEUROLOGICAL DAMAGE AND BEHAVIORAL DEFICITS FROM POSTTRAUMATIC SECONDARY ISCHEMIC INSULTS
Journal of neurotrauma
ADAPTATION OF THE FLUID PERCUSSION INJURY MODEL TO THE MOUSE
Journal of neurotrauma
NOVEL PHARMACOLOGICAL STRATEGIES IN THE TREATMENT OF EXPERIMENTAL TRAUMATIC BRAIN INJURY - 1998
Journal of neurotrauma
Effect of traumatic brain injury on mouse spatial and nonspatial learning in the Barnes circular maze
JOURNAL OF NEUROTRAUMA
IMMUNOBLOT ANALYSES OF THE RELATIVE CONTRIBUTIONS OF CYSTEINE AND ASPARTIC PROTEASES TO NEUROFILAMENT BREAKDOWN PRODUCTS FOLLOWING EXPERIMENTAL BRAIN INJURY IN RATS
Neurochemical research
POSTTRAUMATIC HYPOTHERMIA IN THE TREATMENT OF AXONAL DAMAGE IN AN ANIMAL-MODEL OF TRAUMATIC AXONAL INJURY
Journal of neurosurgery
TWOFOLD OVEREXPRESSION OF HUMAN BETA-AMYLOID PRECURSOR PROTEINS IN TRANSGENIC MICE DOES NOT AFFECT THE NEUROMOTOR, COGNITIVE, OR NEURODEGENERATIVE SEQUELAE FOLLOWING EXPERIMENTAL BRAIN INJURY
Journal of comparative neurology
CHRONIC EFFECTS OF TRAUMATIC BRAIN INJURY ON HIPPOCAMPAL VESICULAR ACETYLCHOLINE TRANSPORTER AND M-2 MUSCARINIC RECEPTOR PROTEIN IN RATS
Experimental neurology
EFFECT OF HYPOTHERMIA, DICHLOROACETATE, AND DEFEROXAMINE IN THE TREATMENT FOR CORTICAL EDEMA AND FUNCTIONAL RECOVERY AFTER EXPERIMENTAL CORTICAL IMPACT IN THE RAT
Academic emergency medicine
THE EFFECT OF BRAIN TEMPERATURE ON ACUTE-INFLAMMATION AFTER TRAUMATICBRAIN INJURY IN RATS
Journal of neurotrauma
EARLY NEUROPATHOLOGIC EFFECTS OF MILD OR MODERATE HYPOXEMIA AFTER CONTROLLED CORTICAL IMPACT INJURY IN RATS
Journal of neurotrauma
EFFECTS OF THE NOVEL NMDA ANTAGONISTS CP-98,113, CP-101,581 AND CP-101,606 ON COGNITIVE FUNCTION AND REGIONAL CEREBRAL EDEMA FOLLOWING EXPERIMENTAL BRAIN INJURY IN THE RAT
Journal of neurotrauma
MOTOR AND COGNITIVE FUNCTIONAL DEFICITS FOLLOWING DIFFUSE TRAUMATIC BRAIN INJURY IN THE IMMATURE RAT
Journal of neurotrauma
A CONCUSSIVE-LIKE BRAIN INJURY MODEL IN MICE .1. IMPAIRMENT IN LEARNING AND MEMORY
Journal of neurotrauma
IS HIGH EXTRACELLULAR GLUTAMATE THE KEY TO EXCITOTOXICITY IN TRAUMATIC BRAIN INJURY
Journal of neurotrauma
MITOCHONDRIAL DYSFUNCTION AND CALCIUM PERTURBATION INDUCED BY TRAUMATIC BRAIN INJURY
Journal of neurotrauma
MOTOR AND COGNITIVE DEFICITS IN APOLIPOPROTEIN E-DEFICIENT MICE AFTERCLOSED-HEAD INJURY
Neuroscience
THE BIPHASIC OPENING OF THE BLOOD-BRAIN-BARRIER IN THE CORTEX AND HIPPOCAMPUS AFTER TRAUMATIC BRAIN INJURY IN RATS
Neuroscience letters
ASSESSMENT OF CEREBRAL BLOOD-FLOW AND CO2 REACTIVITY AFTER CONTROLLEDCORTICAL IMPACT BY PERFUSION MAGNETIC-RESONANCE-IMAGING USING ARTERIAL SPIN-LABELING IN RATS
Journal of cerebral blood flow and metabolism
NERVE GROWTH-FACTOR ATTENUATES CHOLINERGIC DEFICITS FOLLOWING TRAUMATIC BRAIN INJURY IN RATS
Experimental neurology
HISTOLOGICAL MARKERS OF NEURONAL, AXONAL AND ASTROCYTIC CHANGES AFTERLATERAL RIGID IMPACT TRAUMATIC BRAIN INJURY
Brain research
EVALUATION OF LEARNING AND MEMORY DYSFUNCTION AND HISTOLOGICAL-FINDINGS IN RATS WITH CHRONIC STAGE CONTUSION AND DIFFUSE AXONAL INJURY
Brain research
REDUCED EVOKED RELEASE OF ACETYLCHOLINE IN THE RODENT NEOCORTEX FOLLOWING TRAUMATIC BRAIN INJURY
Brain research
MILD HYPOTHERMIA AND OUTCOME AFTER CPR
Acta anaesthesiologica Scandinavica
EFFECT OF DIFLUOROMETHYLORNITHINE TREATMENT ON REGIONAL ORNITHINE DECARBOXYLASE ACTIVITY AND EDEMA FORMATION AFTER EXPERIMENTAL BRAIN INJURY
Journal of neurotrauma
RILUZOLE, A NOVEL NEUROPROTECTIVE AGENT, ATTENUATES BOTH NEUROLOGIC MOTOR AND COGNITIVE DYSFUNCTION FOLLOWING EXPERIMENTAL BRAIN INJURY IN THE RAT
Journal of neurotrauma
AN EXPERIMENTAL-MODEL OF CLOSED-HEAD INJURY IN MICE - PATHOPHYSIOLOGY, HISTOPATHOLOGY, AND COGNITIVE DEFICITS
Journal of neurotrauma
MILD POSTTRAUMATIC HYPOTHERMIA REDUCES MORTALITY AFTER SEVERE CONTROLLED CORTICAL IMPACT IN RATS
Journal of cerebral blood flow and metabolism