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La ricerca find articoli where soggetti phrase all words 'COMBINATORIAL LIBRARIES' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 606 riferimenti
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    1. Nicacio, CD; Williamson, RA; Parren, PWHI; Lundkvist, A; Burton, DR; Bjorling, E
      Neutralizing human Fab fragments against measles virus recovered by phage display

      JOURNAL OF VIROLOGY
    2. Xue, L; Godden, JW; Stahura, FL; Bajorath, J
      A dual fingerprint-based metric for the design of focused compound libraries and analogs

      JOURNAL OF MOLECULAR MODELING
    3. Yu, YP; Ostresh, JM; Houghten, RA
      Solid-phase synthesis of 1,7-disubstituted-1,3,5-triazepane-2,4-diones

      ORGANIC LETTERS
    4. Acharya, AN; Nefzi, A; Ostresh, JM; Houghten, RA
      Tethered libraries: Solid-phase synthesis of substituted urea-linked bicyclic guanidines

      JOURNAL OF COMBINATORIAL CHEMISTRY
    5. Organ, MG; Mayhew, D; Cooper, JT; Dixon, CE; Lavorato, DJ; Kaldor, SW; Siegel, MG
      Solution phase synthesis of libraries of variably substituted olefin scaffolds: A library of allylic amines

      JOURNAL OF COMBINATORIAL CHEMISTRY
    6. Nefzi, A; Giulianotti, MA; Houghten, RA
      Solid-phase synthesis of bis-heterocyclic compounds from resin-bound orthogonally protected lysine

      JOURNAL OF COMBINATORIAL CHEMISTRY
    7. Ponsard, I; Galleni, M; Soumillion, P; Fastrez, J
      Selection of metalloenzymes by catalytic activity using phage display and catalytic elution

      CHEMBIOCHEM
    8. Grimstrup, M; Zaragoza, F
      Synthesis of a new class of highly functionalised benzamides by threefold sequential nucleophilic substitution at a resin-bound polyelectrophile

      EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
    9. Kolb, HC; Finn, MG; Sharpless, KB
      Click chemistry: Diverse chemical function from a few good reactions

      ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
    10. Szewczyk, JW; Zuckerman, RL; Bergman, RG; Ellman, JA
      A mass spectrometric labeling strategy for high-throughput reaction evaluation and optimization: Exploring C-H activation

      ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
    11. Wiesmuller, KH; Fleckenstein, B; Jung, G
      Peptide vaccines and peptide libraries

      BIOLOGICAL CHEMISTRY
    12. van 't Hof, W; Veerman, ECI; Helmerhorst, EJ; Amerongen, AVN
      Antimicrobial peptides: Properties and applicability

      BIOLOGICAL CHEMISTRY
    13. Leena, S; Kumar, KS
      Syntheses, characterization and application of crosslinked polystyrene-ethyleneglycol acrylate resin (CLPSER) as a novel polymer support for polypeptide syntheses

      JOURNAL OF PEPTIDE RESEARCH
    14. Henlin, JM; Boutin, JA; Kucharczyk, N; Desmet-Beaufort, C; Loynel, A; Bertrand, M; Genton, A; Tucker, GC; Atassi, G; Fauchere, JL
      From peptide libraries to optimized nonpeptide ligands in the search for S-farnesyltransferase inhibitors

      JOURNAL OF PEPTIDE RESEARCH
    15. Burgess, K; Han, I; Zhang, A; Zheng, WH; Shanmugam, K; Featherstone, MS; Saragovi, HU
      DiSSiMiL: Diverse Small Size Mini-Libraries applied to simple and rapid epitope mapping of a monoclonal antibody

      JOURNAL OF PEPTIDE RESEARCH
    16. Sidhu, SS
      Engineering M13 for phage display

      BIOMOLECULAR ENGINEERING
    17. Newsam, JM; Bein, T; Klein, J; Maier, WF; Stichert, W
      High throughput experimentation for the synthesis of new crystalline microporous solids

      MICROPOROUS AND MESOPOROUS MATERIALS
    18. Hansson, M; Samuelson, P; Gunneriusson, E; Stahl, S
      Surface display on gram positive bacteria

      COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
    19. Mason, JS; Good, AC; Martin, EJ
      3-D Pharmacophores in drug discovery

      CURRENT PHARMACEUTICAL DESIGN
    20. Hayhurst, A; Georgiou, G
      High-throughput antibody isolation

      CURRENT OPINION IN CHEMICAL BIOLOGY
    21. Alaimo, PJ; Shogren-Knaak, MA; Shokat, KM
      Chemical genetic approaches for the elucidation of signaling pathways

      CURRENT OPINION IN CHEMICAL BIOLOGY
    22. Gedeck, P; Willett, P
      Visual and computational analysis of structure-activity relationships in high-throughput screening data

      CURRENT OPINION IN CHEMICAL BIOLOGY
    23. Hughes, I; Hunter, D
      Techniques for analysis and purification in high-throughput chemistry

      CURRENT OPINION IN CHEMICAL BIOLOGY
    24. Affleck, RL
      Solutions for library encoding to create collections of discrete compounds

      CURRENT OPINION IN CHEMICAL BIOLOGY
    25. Ripka, WC; Barker, G; Krakover, J
      High-throughput purification of compound libraries

      DRUG DISCOVERY TODAY
    26. Jenne, A; Hartig, JS; Piganeau, N; Tauer, A; Samarsky, DA; Green, MR; Davies, J; Famulok, M
      Rapid identification and characterization of hammerhead-ribozyme inhibitors using fluorescence-based technology

      NATURE BIOTECHNOLOGY
    27. Jiang, Y; Lee, CS
      On-line coupling of hollow fiber membranes with electrospray ionization mass spectrometry for continuous affinity selection, concentration and identification of small-molecule libraries

      JOURNAL OF MASS SPECTROMETRY
    28. Prokai, L; Zharikova, A; Janaky, T; Li, XX; Braddy, AC; Perjesi, P; Matveeva, L; Powell, DH; Prokai-Tatrai, K
      Integration of mass spectrometry into early-phase discovery and development of central nervous system agents

      JOURNAL OF MASS SPECTROMETRY
    29. Scott, CP; Abel-Santos, E; Jones, AD; Benkovic, SJ
      Structural requirements for the biosynthesis of backbone cyclic peptide libraries

      CHEMISTRY & BIOLOGY
    30. Zhang, ZW; Ly, T; Kodadek, T
      An inhibitor of sequence-specific proteolysis that targets the substrate rather than the enzyme

      CHEMISTRY & BIOLOGY
    31. Kodadek, T
      Protein microarrays: prospects and problems

      CHEMISTRY & BIOLOGY
    32. Lagerkvist, AC; Foldes-Papp, Z; Persson, MAA; Rigler, R
      Fluorescence correlation spectroscopy as a method for assessment of interactions between phage displaying antibodies and soluble antigen

      PROTEIN SCIENCE
    33. Peretz, D; Scott, MR; Groth, D; Williamson, RA; Burton, DR; Cohen, FE; Prusiner, SB
      Strain-specified relative conformational stability of the scrapie prion protein

      PROTEIN SCIENCE
    34. Woolfson, DN
      Core-directed protein design

      CURRENT OPINION IN STRUCTURAL BIOLOGY
    35. Ladner, RC; Ley, AC
      Novel frameworks as a source of high-affinity ligands

      CURRENT OPINION IN BIOTECHNOLOGY
    36. Kyranos, JN; Cai, H; Wei, D; Goetzinger, WK
      High-throughput high-performance liquid chromatography/mass spectrometry for modern drug discovery

      CURRENT OPINION IN BIOTECHNOLOGY
    37. Wang, T; Barber, M; Hardt, I; Kassel, DB
      Mass-directed fractionation and isolation of pharmaceutical compounds by packed-column supercritical fluid chromatography/mass spectrometry

      RAPID COMMUNICATIONS IN MASS SPECTROMETRY
    38. Sandee, AJ; Petra, DGI; Reek, JNH; Kamer, PCJ; van Leeuwen, PWNM
      Solid-phase synthesis of homogeneous ruthenium catalysts on silica for thecontinuous asymmetric transfer hydrogenation reaction

      CHEMISTRY-A EUROPEAN JOURNAL
    39. Wennemers, H; Conza, M; Nold, M; Krattiger, P
      Diketopiperazine receptors: A novel class of highly selective receptors for binding small peptides

      CHEMISTRY-A EUROPEAN JOURNAL
    40. Chataigner, I; Gennari, C; Ongeri, S; Piarulli, U; Ceccarelli, S
      Discovery of a new efficient chiral ligand for copper-catalyzed enantioselective Michael additions by high-throughput screening of a parallel library

      CHEMISTRY-A EUROPEAN JOURNAL
    41. Jacobsen, M; Cepok, S; Oertel, WH; Sommer, N; Hemmer, B
      New approaches to dissect degeneracy and specificity in T cell antigen recognition

      JOURNAL OF MOLECULAR MEDICINE-JMM
    42. Curran, DP
      Fluorous reverse phase silica gel. A new tool for preparative separations in synthetic organic and organofluorine chemistry

      SYNLETT
    43. Shuker, SB; Esterbrook, J; Gonzalez, J
      Solid-phase synthesis of a novel peptide substituted calix[4]arene

      SYNLETT
    44. Crego-Calama, M; Reinhoudt, DN
      New materials for metal ion sensing by self-assembled monolayers on glass

      ADVANCED MATERIALS
    45. Thomson, S; Hoffmann, C; Ruthe, S; Schmidt, HW; Schuth, F
      The development of a high throughput reactor for the catalytic screening of three phase reactions

      APPLIED CATALYSIS A-GENERAL
    46. Rarey, M; Stahl, M
      Similarity searching in large combinatorial chemistry spaces

      JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
    47. Martin, R; Gran, B; Zhao, YD; Markovic-Plese, S; Bielekova, B; Marques, A; Sung, MH; Hemmer, B; Simon, R; McFarland, HF; Pinilla, C
      Molecular mimicry and antigen-specific T cell responses in multiple sclerosis and chronic CNS lyme disease

      JOURNAL OF AUTOIMMUNITY
    48. Syage, JA; Evans, MD
      Photoionization mass spectrometry - A powerful new tool for drug discovery

      SPECTROSCOPY
    49. Andersson, C; Hansson, M; Power, U; Nygren, PA; Stahl, S
      Mammalian cell production of a respiratory syncytial virus (RSV) candidatevaccine recovered using a product-specific affinity column

      BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY
    50. Benhar, I
      Biotechnological applications of phage and cell display

      BIOTECHNOLOGY ADVANCES
    51. Schoonjans, V; Massart, DL
      Combining spectroscopic data (MS, IR): exploratory chemometric analysis for characterising similarity/diversity of chemical structures

      JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
    52. Papac, DI; Shahrokh, Z
      Mass spectrometry innovations in drug discovery and development

      PHARMACEUTICAL RESEARCH
    53. Greig, LM; Philp, D
      Applying biological principles to the assembly and selection of synthetic superstructures

      CHEMICAL SOCIETY REVIEWS
    54. Thennarasu, S; Nagaraj, R
      Effects of salt and denaturant on structure of the amino terminal alpha-helical segment of an antibacterial peptide dermaseptin and its binding to model membranes

      INDIAN JOURNAL OF BIOCHEMISTRY & BIOPHYSICS
    55. Bugli, F; Bastidas, R; Burton, DR; Williamson, RA; Clementi, M; Burioni, R
      Molecular profile of a human monoclonal antibody Fab fragment specific forEpstein-Barr virus gp350/220 antigen

      HUMAN IMMUNOLOGY
    56. Reetz, MT; Hermes, M; Becker, MH
      Infrared-thermographic screening of the activity and enantioselectivity ofenzymes

      APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
    57. Lynen, F; Borremans, F; Sandra, P
      Practical evaluation of the influence of excessive sample concentration onthe estimation of dissociation constants with affinity capillary electrophoresis

      ELECTROPHORESIS
    58. Josic, D; Buchacher, A
      Application of monoliths as supports for affinity chromatography and fast enzymatic conversion

      JOURNAL OF BIOCHEMICAL AND BIOPHYSICAL METHODS
    59. Kjaergaard, K; Schembri, MA; Klemm, P
      Novel Zn2+-chelating peptides selected from a fimbria-displayed random peptide library

      APPLIED AND ENVIRONMENTAL MICROBIOLOGY
    60. Agrafiotis, DK; Rassokhin, DN
      Design and prioritization of plates for high-throughput screening

      JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES
    61. Hann, MM; Leach, AR; Harper, G
      Molecular complexity and its impact on the probability of finding leads for drug discovery

      JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES
    62. Bajorath, J
      Selected concepts and investigations in compound classification, moleculardescriptor analysis, and virtual screening

      JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES
    63. MacCuish, J; Nicolaou, C; MacCuish, NE
      Ties in proximity and clustering compounds

      JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES
    64. Nemeth, GA; Kassel, DB
      Chapter 27. Existing and emerging strategies for the analytical characterization and profiling of compound libraries

      ANNUAL REPORTS IN MEDICINAL CHEMISTRY, VOL 36
    65. Barbas, CF; Rader, C; Segal, DJ; List, B; Turner, JM
      From catalytic asymmetric synthesis to the transcriptional regulation of genes: In vivo and in vitro evolution of proteins

      ADVANCES IN PROTEIN CHEMISTRY, VOL 55
    66. Pluckthun, A; Schaffitzel, C; Hanes, J; Jermutus, L
      In vitro selection and evolution of proteins

      ADVANCES IN PROTEIN CHEMISTRY, VOL 55
    67. Yu, YP; El Abdellaoui, HM; Ostresh, JM; Houghten, RA
      Solid phase synthesis of [3,5,7]-1H-imidazo[1,5-a]imidazol-2(3H)-ones

      TETRAHEDRON LETTERS
    68. Quiroga, J; Cisneros, C; Insuasty, B; Abonia, R; Nogueras, M; Sanchez, A
      A regiospecific three-component one-step cyclocondensation to 6-cyano-5,8-dihydropyrido[2,3-d]pyrimidin-4(3H)-ones using microwaves under solvent-free conditions

      TETRAHEDRON LETTERS
    69. Orain, D; Bradley, M
      Solid phase synthesis of trypanothione reductase inhibitors - towards single bead screening

      TETRAHEDRON LETTERS
    70. Fujii, I; Takaoka, Y; Suzuki, K; Tanaka, T
      A conformationally purified alpha-helical peptide library

      TETRAHEDRON LETTERS
    71. Motherwell, WB; Bingham, MJ; Six, Y
      Recent progress in the design and synthesis of artificial enzymes

      TETRAHEDRON
    72. Tai, KK; Blondelle, SE; Ostresh, JM; Houghten, RA; Montal, M
      An N-methyl-D-aspartate receptor channel blocker with neuroprotective activity

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    73. Williamson, RA; Burgoon, MP; Owens, GP; Ghausi, O; Leclerc, E; Firme, L; Carlson, S; Corboy, J; Parren, PWHI; Sanna, PP; Gilden, DH; Burton, DR
      Anti-DNA antibodies are a major component of the intrathecal B cell response in multiple sclerosis

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    74. Zwick, MB; Labrijn, AF; Wang, M; Spenlehauer, C; Saphire, EO; Binley, JM; Moore, JP; Stiegler, G; Katinger, H; Burton, DR; Parren, PWHI
      Broadly neutralizing antibodies targeted to the membrane-proximal externalregion of human immunodeficiency virus type 1 glycoprotein gp41

      JOURNAL OF VIROLOGY
    75. Zwick, MB; Bonnycastle, LLC; Menendez, A; Irving, MB; Barbas, CF; Parren, PWHI; Burton, DR; Scott, JK
      Identification and characterization of a peptide that specifically binds the human, broadly neutralizing anti-human immunodeficiency virus type 1 antibody b12

      JOURNAL OF VIROLOGY
    76. Star, A; Goldberg, I; Fuchs, B
      Diazadioxadecalin and salen podands and macrocycles within dynamic combinatorial virtual libraries: structure, prototropy, complexation and enantioselective catalysis

      JOURNAL OF ORGANOMETALLIC CHEMISTRY
    77. Ghosh, JK; Hol, WGJ; Fan, EK
      Solid-phase synthesis of N-acyl-N '-alkyl/aryl disubstituted guanidines

      JOURNAL OF ORGANIC CHEMISTRY
    78. Acharya, AN; Ostresh, JM; Houghten, RA
      A novel approach for solid-phase synthesis of substituted imidazolines andbis-imidazolines

      JOURNAL OF ORGANIC CHEMISTRY
    79. Cossy, J; Rasamison, C; Pardo, DG
      Reactivity of alpha-(benzoyloxy)crotylstannane with aldehydes in liquid phase and on solid support. Synthesis of substituted lactones

      JOURNAL OF ORGANIC CHEMISTRY
    80. Linusson, A; Gottfries, J; Olsson, T; Ornskov, E; Folestad, S; Norden, B; Wold, S
      Statistical molecular design, parallel synthesis, and biological evaluation of a library of thrombin inhibitors

      JOURNAL OF MEDICINAL CHEMISTRY
    81. Llorens, O; Perez, JJ; Villar, HO
      Toward the design of chemical libraries for mass screening biased against mutagenic compounds

      JOURNAL OF MEDICINAL CHEMISTRY
    82. Muegge, I; Heald, SL; Brittelli, D
      Simple selection criteria for drug-like chemical matter

      JOURNAL OF MEDICINAL CHEMISTRY
    83. Trollmo, C; Meyer, AL; Steere, AC; Hafler, DA; Huber, BT
      Molecular mimicry in Lyme arthritis demonstrated at the single cell level:LFA-1 alpha(L) is a partial agonist for outer surface protein A-reactive Tcells

      JOURNAL OF IMMUNOLOGY
    84. Geginat, G; Schenk, S; Skoberne, M; Goebel, W; Hof, H
      A novel approach of direct ex vivo epitope mapping identifies dominant andsubdominant CD4 and CD8 T cell epitopes from Listeria monocytogenes

      JOURNAL OF IMMUNOLOGY
    85. Judkowski, V; Pinilla, C; Schroder, K; Tucker, L; Sarvetnick, N; Wilson, DB
      Identification of MHC class II-restricted peptide ligands, including a glutamic acid decarboxylase 65 sequence, that stimulate diabetogenic T cells from transgenic BDC2.5 nonobese diabetic mice

      JOURNAL OF IMMUNOLOGY
    86. Hoffmann, C; Schmidt, HW; Schuth, F
      A multipurpose parallelized 49-channel reactor for the screening of catalysts: Methane oxidation as the example reaction

      JOURNAL OF CATALYSIS
    87. Dreier, B; Beerli, RR; Segal, DJ; Flippin, JD; Barbas, CF
      Development of zinc finger domains for recognition of the 5 '-ANN-3 ' family of DNA sequences and their use in the construction of artificial transcription factors

      JOURNAL OF BIOLOGICAL CHEMISTRY
    88. Audinot, V; Beauverger, P; Lahaye, C; Suply, T; Rodriguez, M; Ouvry, C; Lamamy, V; Imbert, J; Rique, H; Nahon, JL; Galizzi, JP; Canet, E; Levens, N; Fauchere, JL; Boutin, JA
      Structure-activity relationship studies of melanin-concentrating hormone (MCH)-related peptide ligands at SLC-1, the human MCH receptor

      JOURNAL OF BIOLOGICAL CHEMISTRY
    89. Niklas, N; Wolf, S; Liehr, G; Anson, CE; Powell, AK; Alsfasser, R
      Ni(II), Cu(II) and Zn(II) complexes of a bifunctional bis(picolyl)amine (bpa) ligand derived from glycine

      INORGANICA CHIMICA ACTA
    90. Russek, SE; Bailey, WE; Alers, G; Abraham, DL
      Magnetic combinatorial thin-film libraries

      IEEE TRANSACTIONS ON MAGNETICS
    91. Krchnak, V; Smith, J; Vagner, J
      Solid-phase traceless synthesis of selected nitrogen-containing heterocyclic compounds. The Encore technique for directed sorting of modular solid support

      COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS
    92. Hoess, RH
      Protein design and phage display

      CHEMICAL REVIEWS
    93. Gilden, DH; Burgoon, MP; Kleinschmidt-DeMasters, BK; Williamson, RA; Ghausi, O; Burton, DR; Owens, GP
      Molecular immunologic strategies to identify antigens and B-cell responsesunique to multiple sclerosis

      ARCHIVES OF NEUROLOGY
    94. Felten, C; Foret, F; Minarik, M; Goetzinger, W; Karger, BL
      Automated high-throughput infusion ESI-MS with direct coupling to a microtiter plate

      ANALYTICAL CHEMISTRY
    95. Moy, FJ; Haraki, K; Mobilio, D; Walker, G; Powers, R; Tabei, K; Tong, H; Siegel, MM
      MS/NMR: A structure-based approach for discovering protein ligands and fordrug design by coupling size exclusion chromatography, mass spectrometry, and nuclear magnetic resonance spectroscopy

      ANALYTICAL CHEMISTRY
    96. Karlstrom, A; Nygren, PA
      Dual labeling of a binding protein allows for specific fluorescence detection of native protein

      ANALYTICAL BIOCHEMISTRY
    97. Sternson, SM; Louca, JB; Wong, JC; Schreiber, SL
      Split-pool synthesis of 1,3-dioxanes leading to arrayed stock solutions ofsingle compounds sufficient for multiple phenotypic and protein-binding assays

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    98. Copeland, GT; Miller, SJ
      Selection of enantioselective acyl transfer catalysts from a pooled peptide library through a fluorescence-based activity assay: An approach to kinetic resolution of secondary alcohols of broad structural scope

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    99. Shi, XD; Fettinger, JC; Davis, JT
      Homochiral G-quadruplexes with Ba2+ but not with K+: The cation programs enantiomeric self-recognition

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    100. Fazal, MA; Roy, BC; Sun, SG; Mallik, S; Rodgers, KR
      Surface recognition of a protein using designed transition metal complexes

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY


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Documento generato il 29/05/20 alle ore 15:44:30