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Fibrosis of the lung and other tissues: New concepts in pathogenesis and treatment
CLINICAL IMMUNOLOGY
Vascular inflammation and activation: new targets for lipid lowering
EUROPEAN HEART JOURNAL SUPPLEMENTS
Chondrocyte phenotype and cell survival are regulated by culture conditions and by specific cytokines through the expression of Sox-9 transcription factor
RHEUMATOLOGY
Impaired intramembranous bone formation during bone repair in the absence of tumor necrosis factor-alpha signaling
CELLS TISSUES ORGANS
Role of cytokines and cytokine therapy in wound healing and fibrotic diseases
CURRENT PHARMACEUTICAL DESIGN
Characterization of immortalized human chondrocytes originated from osteoarthritis cartilage
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
Directed evolution of proteins by exon shuffling
NATURE BIOTECHNOLOGY
High-efficiency non-viral transfection of primary chondrocytes and perichondrial cells for ex-vivo gene therapy to repair articular cartilage defects
OSTEOARTHRITIS AND CARTILAGE
L-Sox5, Sox6 and Sox9 control essential steps of the chondrocyte differentiation pathway
OSTEOARTHRITIS AND CARTILAGE
Role of cartilage-derived anti-angiogenic factor, chondromodulin-I, duringendochondral bone formation
OSTEOARTHRITIS AND CARTILAGE
Impact of mutations of cartilage matrix genes on matrix structure, gene activity and chondrogenesis
OSTEOARTHRITIS AND CARTILAGE
Msx2 is a repressor of chondrogenic differentiation in migratory cranial neural crest cells
DEVELOPMENTAL DYNAMICS
Type IIA procollagen: Expression in developing chicken limb cartilage and human osteoarthritic articular cartilage
DEVELOPMENTAL DYNAMICS
Type IIA procollagen in development of the human intervertebral disc: Regulated expression of the NH2-propeptide by enzymic processing reveals a unique developmental pathway
DEVELOPMENTAL DYNAMICS
Effects of thyroid hormones on cardiac structure: A tissue characterization study in patients with thyroid disorders before and after treatment
THYROID
Bone morphogenetic protein-2 (BMP-2) signaling to the Col2 alpha 1 gene inchondroblasts requires the homeobox gene Dlx-2
DNA AND CELL BIOLOGY
Genetic epidemiology of primary osteoarthritis
CURRENT OPINION IN RHEUMATOLOGY
Gene therapy for inherited skin diseases
CURRENT PROBLEMS IN DERMATOLOGY-US
Regulatory mechanisms in the pathways of cartilage and bone formation
CURRENT OPINION IN CELL BIOLOGY
Smad3/AP-1 interactions control transcriptional responses to TGF-beta in apromoter-specific manner
ONCOGENE
Structural and functional analysis of a chimeric protein COL1A1-PDGFB generated by the translocation t(17;22)(q22;q13.1) in Dermatofibrosarcoma Protuberans (DP)
ONCOGENE
Induction of periosteal callus formation by bone morphogenetic protein-2 employing adenovirus-mediated gene delivery
MATRIX BIOLOGY
Stage-and tissue-specific expression of a Col2a1-Cre fusion gene in transgenic mice
MATRIX BIOLOGY
Analysis of the promoter region of human cartilage oligomeric matrix protein (COMP)
MATRIX BIOLOGY
Two novel alternatively spliced 9-bp exons in the COL4A5 gene
PEDIATRIC NEPHROLOGY
Mechanisms of transcriptional activation of the col6al gene during Schwanncell differentiation
MECHANISMS OF DEVELOPMENT
CHF-1024, a DA(2)/alpha(2) agonist, blunts norepinephrine excretion and cardiac fibrosis in pressure overload
CARDIOVASCULAR DRUGS AND THERAPY
Changes in xylosyltransferase activity and in proteoglycan deposition in bleomycin-induced lung injury in rat
EUROPEAN RESPIRATORY JOURNAL
Both retinoic acid and 1,25(OH)(2) vitamin D-3 inhibit thyroid hormone-induced terminal differentiaton of growth plate chondrocytes
JOURNAL OF ORTHOPAEDIC RESEARCH
Establishment and characterization of chondrocyte cell lines from the costal cartilage of SV40 large T antigen transgenic mice
JOURNAL OF CELLULAR BIOCHEMISTRY
Oxidative stress effect on the activation of hepatic stellate cells
YONSEI MEDICAL JOURNAL
A histomorphometric and molecular study on stress adaptability of freeze-dried bone allograft
CHINESE MEDICAL JOURNAL
Osteogenesis imperfecta at the beginning of bone and joint decade
CROATIAN MEDICAL JOURNAL
Increased frequency of interleukin 4 producing CD4+and CD8+cells in peripheral blood from patients with systemic sclerosis
JOURNAL OF RHEUMATOLOGY
Characterization of mutations leading to recessive dystrophic epidermolysis bullosa and Marfan syndrome in a single patient
CLINICAL AND EXPERIMENTAL DERMATOLOGY
Dominant dystrophic epidermolysis bullosa presenting as familial nail dystrophy
CLINICAL AND EXPERIMENTAL DERMATOLOGY
Three cases of de novo dominant dystrophic epidermolysis bullosa associated with the mutation G2043R in COL7A1
CLINICAL AND EXPERIMENTAL DERMATOLOGY
Familial hematuric syndromes - Alport syndrome, thin glomerular basement membrane disease and Fechtner/Epstein syndromes
RARE KIDNEY DISEASES
Effects of crocidolite asbestos on human bronchoepithelial-dependent fibroblast stimulation in coculture: the role of IL-6 and GM-CSF
TOXICOLOGY
Transcriptional regulation in hepatic stellate cells
SEMINARS IN LIVER DISEASE
Cytokine receptors and signaling in hepatic stellate cells
SEMINARS IN LIVER DISEASE
The role of Smad3 in mediating mouse hepatic stellate cell activation
HEPATOLOGY
Idiopathic weight reduction in mice deficient in the high-mobility-group transcription factor Sox8
MOLECULAR AND CELLULAR BIOLOGY
Heart, aging, and hypertension
CURRENT OPINION IN CARDIOLOGY
Regression of renal vascular fibrosis by endothelin receptor antagonism
HYPERTENSION
Effects of fibrogenic mediators on the development of pancreatic fibrosis in a TGF-beta 1 transgenic mouse model
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
Alport disease: A review of the diagnostic difficulties
ULTRASTRUCTURAL PATHOLOGY
Wnts differentially regulate colony growth and differentiation of chondrogenic rat calvaria cells
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
Separation of amniotic membranes after amniocentesis in an individual withthe classic form of EDS and haploinsufficiency for COL5A1 expression
AMERICAN JOURNAL OF MEDICAL GENETICS
A novel model to study renal myofibroblast formation in vitro
KIDNEY INTERNATIONAL
Glycated albumin stimulates TGF-beta 1 production and protein kinase C activity in glomerular endothelial cells
KIDNEY INTERNATIONAL
Hydrogen peroxide increases extracellular matrix mRNA through TGF-beta in human mesangial cells
KIDNEY INTERNATIONAL
Cytokines, growth factors, and plastic surgery
PLASTIC AND RECONSTRUCTIVE SURGERY
Abnormal balance between proliferation and apoptotic cell death in fibroblasts derived from keloid lesions
PLASTIC AND RECONSTRUCTIVE SURGERY
UVA-340 as energy source, mimicking natural sunlight, activates the transcription factor AP-1 in cultured fibroblasts: Evidence for involvement of protein Kinase-C
PHOTOCHEMISTRY AND PHOTOBIOLOGY
Nuclear hormone receptor CHR3 is a critical regulator of all four larval molts of the nematode Caenorhabditis elegans
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Haploinsufficiency of Sox9 results in defective cartilage primordia and premature skeletal mineralization
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
The chondrogenic transcription factor Sox9 is a target of signaling by theparathyroid hormone-related peptide in the growth plate of endochondral bones
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Keratinocyte-derived growth factors play a role in the formation of hypertrophic scars
JOURNAL OF PATHOLOGY
Localisation of a gene for an autosomal recessive syndrome of macrocephaly, multiple epiphyseal dysplasia, and distinctive facies to chromosome 15q26
JOURNAL OF MEDICAL GENETICS
Homozygosity for a splice site mutation of the COL1A2 gene yields a non-functional pro alpha 2(I) chain and an EDS/OI clinical phenotype
JOURNAL OF MEDICAL GENETICS
Blocking Sp1 transcription factor broadly inhibits extracellular matrix gene expression in vitro and in vivo: Implications for the treatment of tissue fibrosis
JOURNAL OF INVESTIGATIVE DERMATOLOGY
Epidermolysis bullosa carrier frequencies in the US population
JOURNAL OF INVESTIGATIVE DERMATOLOGY
Lack of skin fibrosis in tight skin (TSK) mice with targeted mutation in the interleukin-4R alpha and transforming growth factor-beta genes
JOURNAL OF INVESTIGATIVE DERMATOLOGY
Regulation of male sexual development by Sry and Sox9
JOURNAL OF EXPERIMENTAL ZOOLOGY
BMP-2 and BMP-9 promote chondrogenic differentiation of human multipotential mesenchymal cells and overcome the inhibitory effect of IL-1
JOURNAL OF CELLULAR PHYSIOLOGY
Role of phosphoinositide 3OH-kinase in autocrine transformation by PDGF-BB
JOURNAL OF CELLULAR PHYSIOLOGY
Regulation of heparan sulfate proteoglycan nuclear localization by fibronectin
JOURNAL OF CELL SCIENCE
The transcription factor SOX9 regulates cell cycle and differentiation genes in chondrocytic CFK2 cells.
JOURNAL OF BIOLOGICAL CHEMISTRY
YY1 is a positive regulator of transcription of the Col1a1 gene
JOURNAL OF BIOLOGICAL CHEMISTRY
SP3 represses the SP1-mediated transactivation of the human COL2A1 gene inprimary and de-differentiated chondrocytes
JOURNAL OF BIOLOGICAL CHEMISTRY
Identification of an internal gene to the human galectin-3 gene with two different overlapping reading frames that do not encode galectin-3
JOURNAL OF BIOLOGICAL CHEMISTRY
Alterations in the sensing and transport of phosphate and calcium by differentiating chondrocytes
JOURNAL OF BIOLOGICAL CHEMISTRY
Compound effects of point mutations causing campomelic dysplasia/autosomalsex reversal upon SOX9 structure, nuclear transport, DNA binding, and transcriptional activation
JOURNAL OF BIOLOGICAL CHEMISTRY
Identification of novel TGF-beta/Smad gene targets in dermal fibroblasts using a combined cDNA microarray/promoter transactivation approach
JOURNAL OF BIOLOGICAL CHEMISTRY
COL5A1 exon 14 splice acceptor mutation causes a functional null allele, haploinsufficiency of alpha 1(V) and abnormal heterotypic interstitial fibrils in Ehlers-Danlos syndrome II
JOURNAL OF BIOLOGICAL CHEMISTRY
Phosphate stimulates differentiation and mineralization of the chondroprogenitor clone ATDC5
JAPANESE JOURNAL OF PHARMACOLOGY
Growth-inhibitory effect of STI571 on cells transformed by the COL1A1/PDGFB rearrangement
INTERNATIONAL JOURNAL OF CANCER
Apigenin decreases expression of the myofibroblast phenotype
FEBS LETTERS
Identification of an interaction between SOX9 and HSP70
FEBS LETTERS
Age-dependent changes in the expression of matrix components in the mouse eye
EXPERIMENTAL EYE RESEARCH
Direct inhibition of Indian hedgehog expression by parathyroid hormone (PTH)/PTH-related peptide and up-regulation by retinoic acid in growth plate chondrocyte cultures
EXPERIMENTAL CELL RESEARCH
Testing life-history pleiotropy in Caenorhabditis elegans
EVOLUTION
Structure and promoter analysis of the mouse membrane-bound transferrin-like protein (MTf) gene
EUROPEAN JOURNAL OF BIOCHEMISTRY
Cloning and characterization of the proximal murine Phex promoter
ENDOCRINOLOGY
Signal-selectivity of parathyroid hormone (PTH)/PTH-related peptide receptor-mediated regulation of differentiation in conditionally immortalized growth-plate chondrocytes
ENDOCRINOLOGY
Two sox9 genes on duplicated zebrafish chromosomes: Expression of similar transcription activators in distinct sites
DEVELOPMENTAL BIOLOGY
Preclinical cartilage repair - Current status and future perspectives
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH
Myocardial fibrosis in DOCA-salt hypertensive rats - Effect of endothelin ETA receptor antagonism
CIRCULATION
Growth inhibition of dermatofibrosarcoma protuberans tumors by the platelet-derived growth factor receptor antagonist STI571 through induction of apoptosis
CANCER RESEARCH
Generalized dystrophic epidermolysis bullosa: identification of a novel, homozygous glycine substitution, G2031S, in exon 73 of COL7A1 in monozygous triplets
BRITISH JOURNAL OF DERMATOLOGY
Localisation of the SRY-related HMG box protein, SOX9, in rodent brain
BRAIN RESEARCH
A 30-base-pair element in them first intron of SOX9 acts as an enhancer inATDC5
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
ERK mediates effects of glycated albumin in mesangial cells
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Overexpression of connective tissue growth factor hypertrophic chondrocyte-specific gene product 24 decreases bone density in adult mice and induces dwarfism
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Mutation analysis of the entire PKD1 gene: Genetic and diagnostic implications
AMERICAN JOURNAL OF HUMAN GENETICS
Co/2a1-directed expression of Cre recombinase in differentiating chondrocytes in transgenic mice
GENESIS
New strategies for the control of plant-parasitic nematodes
PEST MANAGEMENT SCIENCE
Linkage analysis of candidate genes as susceptibility loci for osteoarthritis - suggestive linkage of COL9A1 to female hip osteoarthritis
RHEUMATOLOGY
A novel type X collagen gene mutation (G595R) associated with Schmid-type metaphyseal chondrodysplasia
JOURNAL OF HUMAN GENETICS