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Hepatic artery thrombosis after orthotopic liver transplantation: A reviewof nonsurgical causes
LIVER TRANSPLANTATION
Porcine factor V: cDNA cloning, gene mapping, three-dimensional protein modeling of membrane binding sites and comparative anatomy of domains
CELLULAR AND MOLECULAR LIFE SCIENCES
Two rare confounding polymorphisms proximal to the factor V Leiden mutation
MOLECULAR DIAGNOSIS
Analysis of the factor V Leiden mutation using the READIT Assay
MOLECULAR DIAGNOSIS
Elevated factor VIII levels and the risk of thrombosis
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
The impact of Factor V mutation on the risk for occlusion in patients undergoing peripheral vascular reconstructions
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
Factor V Leiden, prothrombin gene G20210A variant, and methylenetetrahydrofolate reductase C677T genotype in young adults with ischemic stroke
CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS
Factor V Leiden and prothrombin G20210A in relation to arterial and/or vein rethrombosis: Two cases
CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS
Factor V Leiden mutation: potential thrombogenic role in renal vein, dialysis graft and transplant vascular thrombosis
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION
Coexistence of the methylenetetrahydrofolate reductase single-nucleotide polymorphism (C677T) in patients with the factor V Leiden or prothrombin G20210A polymorphisms
DIAGNOSTIC MOLECULAR PATHOLOGY
Modification of the ProC (R) Global assay using dilution of patient plasmain factor V-depleted plasma as a screening assay for factor V Leiden mutation
BLOOD COAGULATION & FIBRINOLYSIS
The factor V HR2 haplotype: prevalence and association of the A4070G and A6755G polymorphisms
BLOOD COAGULATION & FIBRINOLYSIS
Hemostatic and fibrinolytic parameters in survivors of myocardial infarction: a low plasma level of plasmin-alpha 2-antiplasmin complex is an independent predictor of coronary re-events
BLOOD COAGULATION & FIBRINOLYSIS
Tissue-restricted expression of thrombomodulin in the placenta rescues thrombomodulin-deficient mice from early lethality and reveals a secondary developmental block
DEVELOPMENT
Factor V R506Q mutation-Leiden: An independent risk factor for venous thrombosis but not coronary artery disease
JOURNAL OF THROMBOSIS AND THROMBOLYSIS
Myocardial infarction in patients with normal coronary arteries: Proposed pathogenesis and predisposing risk factors
JOURNAL OF THROMBOSIS AND THROMBOLYSIS
Basilar artery thrombosis in a child heterozygous for factor V Leiden mutation
PEDIATRIC NEUROLOGY
Low prevalence of large intraventricular haemorrhage in very low birthweight infants carrying the factor V Leiden or prothrombin G20210A mutation
ACTA PAEDIATRICA
Survey of factor V Leiden and prothrombin gene mutations in systemic lupuserythematosus
CLINICAL RHEUMATOLOGY
G20210A mutation in the prothrombin gene and the risk of recurrent venous thromboembolism
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
Two common genetic thrombotic risk factors: Factor V Leiden and prothrombin G20210A in adult Turkish patients with thrombosis
AMERICAN JOURNAL OF HEMATOLOGY
Platelet factor V New York: A defect in factor V distinct from that in factor V Quebec resulting in impaired prothrombinase generation
AMERICAN JOURNAL OF HEMATOLOGY
Prevalence and association of the factor V Leiden and prothrombin G20210A in healthy subjects and patients with venous thromboembolism
CROATIAN MEDICAL JOURNAL
Genetic risk factors of venous thrombosis
HUMAN GENETICS
Genetic polymorphisms to evaluate the risk of myocardial infarction: a long way away
THROMBOSIS AND HAEMOSTASIS
Imbalance of plasminogen activator inhibitor-I/tissue plasminogen activator and tissue factor/tissue factor pathway inhibitor in young Japanese men with myocardial infarction
THROMBOSIS AND HAEMOSTASIS
Platelets and phospholipids in tissue factor-initiated thrombin generation
THROMBOSIS AND HAEMOSTASIS
Risk factors in venous thromboembolism
THROMBOSIS AND HAEMOSTASIS
The epidemiology of venous thromboembolism in the community
THROMBOSIS AND HAEMOSTASIS
A cell-based model of hemostasis
THROMBOSIS AND HAEMOSTASIS
Fine mapping of inhibitory anti-factor V antibodies using factor V C2 domain mutants - Identification of two antigenic epitopes involved in phospholipid binding
THROMBOSIS AND HAEMOSTASIS
Conventional fibrinolytic assays for the evaluation of patients with venous thrombosis: Don't bother
THROMBOSIS AND HAEMOSTASIS
The Glasgow outcome, APCR and lipid (GOAL) pregnancy study: Significance of pregnancy associated activated protein C resistance
THROMBOSIS AND HAEMOSTASIS
Functional properties of factor V and factor Va encoded by the R2-gene
THROMBOSIS AND HAEMOSTASIS
Patients with persistent APC-resistance without factor V Leiden mutation
VASA-JOURNAL OF VASCULAR DISEASES
Factor V-LEIDEN and cardiopulmonary bypass: investigation of haemostatic parameters and the effect of aprotinin using an ex vivo model
PERFUSION-UK
Thrombo-embolic disease - Prevalence of factor V Leiden in the Western Cape
SOUTH AFRICAN MEDICAL JOURNAL
Acquired factor V inhibitor: aetiology, bleeding risk and treatment with regard to three cases.
REVUE DE MEDECINE INTERNE
Acute liver failure
JOURNAL OF CLINICAL GASTROENTEROLOGY
A patient defines the interstitial 1q deletion syndrome characterized by antithrombin III deficiency
AMERICAN JOURNAL OF MEDICAL GENETICS
Hormone replacement therapy, prothrombotic mutations, and the risk of incident nonfatal myocardial infarction in postmenopausal women
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
Sensitivity of the ProC((R)) global assay for protein C pathway abnormalities. Clinical experience in 899 unselected patients with venous thromboembolism
THROMBOSIS RESEARCH
Importance of hyperhomocysteinemia as a risk factor for venous thromboembolism in a Taiwanese population. A case-control study
THROMBOSIS RESEARCH
Coexistence of thrombophilic gene polymorphisms among 559 unrelated consecutive patients with a history of thrombosis
THROMBOSIS RESEARCH
Inherited thrombophilia in ischemic stroke and its pathogenic subtypes
STROKE
Hypercoagulability: Clinical assessment and treatment
SOUTHERN MEDICAL JOURNAL
The role of protein C, protein S, and resistance to activated protein C inLegg-Perthes disease
PEDIATRICS
Genetic aspects of the hemostatic system in cerebrovascular disease
NEUROLOGY
Homocysteine inhibits inactivation of Factor Va by activated protein C
JOURNAL OF BIOLOGICAL CHEMISTRY
Mapping of epitopes in discoidin domain receptor 1 critical for collagen binding
JOURNAL OF BIOLOGICAL CHEMISTRY
An extensive interaction interface between thrombin and factor V is required for factor V activation
JOURNAL OF BIOLOGICAL CHEMISTRY
Mechanism of factor Va inactivation by plasmin - Loss of A2 and A3 domainsfrom a Ca2+-dependent complex of fragments bound to phospholipid
JOURNAL OF BIOLOGICAL CHEMISTRY
The role of the membrane in the inactivation of factor Va by plasmin - Amino acid region 307-348 of factor V plays a critical role in factor Va cofactor function
JOURNAL OF BIOLOGICAL CHEMISTRY
Laboratory investigation of thrombophilia
CLINICAL CHEMISTRY
Linked linear amplification: A new method for the amplification of DNA
CLINICAL CHEMISTRY
Investigation and management of heritable thrombophilia
BRITISH JOURNAL OF HAEMATOLOGY
High factor VIII levels contribute to the thrombotic risk in families withfactor V Leiden
BRITISH JOURNAL OF HAEMATOLOGY
Structure of a factor VIIIC2 domain-immunoglobulin G4 kappa Fab complex: identification of an inhibitory antibody epitope on the surface of factor VIII
BLOOD
Discrepancy between phenotype and genotype on screening for factor V Leiden after transplantation
BLOOD
Antigenicity of putative phospholipid membrane-binding residues in factor VIII
BLOOD
Soluble phosphatidylserine binds to a single identified site in the C2 domain of human factor V-a
BIOCHEMISTRY
An update on hypercoagulable disorders
ARCHIVES OF INTERNAL MEDICINE
Immunologic impact and clinical outcomes after surgical exposure to bovinethrombin
ANNALS OF SURGERY
A prospective study of asymptomatic carriers of the factor V Leiden mutation to determine the incidence of venous thromboembolism
ANNALS OF INTERNAL MEDICINE
The thrombophilias: Well-defined risk factors with uncertain therapeutic implications
ANNALS OF INTERNAL MEDICINE
Joint effect of G1691A factor V point mutation and factor VII Arg/Gln(353)gene polymorphism on the risk of premature coronary artery disease
ANNALES DE GENETIQUE
Factor V Leiden: A clinical review
AMERICAN JOURNAL OF THE MEDICAL SCIENCES
Factors v Leiden and II 20210A in patients with symptomatic pulmonary embolism and deep vein thrombosis
AMERICAN JOURNAL OF MEDICINE
Factor V Leiden and its relation to left ventricular thrombus in acute myocardial infarction
ACTA CARDIOLOGICA
Real-time polymerase chain reaction with fluorescent hybridization probes for the detection of prevalent mutations causing common thrombophilic and iron overload phenotypes
AJCP. American journal of clinical pathology
Use and validation of selection criteria for liver transplantation in acute liver failure
LIVER TRANSPLANTATION
Analytical evaluation of primer engineered multiplex polymerase chain reaction-restriction fragment length polymorphism for detection of factor V Leiden and prothrombin G20210A
JOURNAL OF MOLECULAR DIAGNOSTICS
Factor V antigen levels and venous thrombosis - Risk profile, interaction with factor V Leiden, and relation with factor VIII antigen levels
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
Hereditary and acquired thrombophilia
SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE
DNA technology for the detection of common genetic variants that predispose to thrombophilia
BLOOD COAGULATION & FIBRINOLYSIS
Comparison of thrombotic risk between 85 homozygotes and 481 heterozygotescarriers of the factor V Leiden mutation: retrospective analysis from the Procare Study
BLOOD COAGULATION & FIBRINOLYSIS
Method-dependent influence of certain polymorphisms in the factor VB-domain on the response to activated protein C
BLOOD COAGULATION & FIBRINOLYSIS
Screening for abnormalities of the protein C anticoagulant pathway using the ProC Global assay. Results of a European multicenter evaluation
BLOOD COAGULATION & FIBRINOLYSIS
Multiple analysis of three common genetic alterations associated with thrombophilia
BLOOD COAGULATION & FIBRINOLYSIS
Mutations in a potential phospholipid binding loop in the C2 domain of factor V affecting the assembly of the prothrombinase complex
BLOOD COAGULATION & FIBRINOLYSIS
Predictors of left ventricular thrombus formation in patients with anterior myocardial infarction: role of activated protein C resistance
CORONARY ARTERY DISEASE
Evaluation of a highly specific functional test for the detection of factor V Leiden
INTERNATIONAL JOURNAL OF CLINICAL & LABORATORY RESEARCH
Incidence of factor V Leiden in patients with acute myocardial infarction
JOURNAL OF THROMBOSIS AND THROMBOLYSIS
Resistance to activated protein C and FV Leiden mutation in patients with a history of acute myocardial infarction or primary hypertension
AMERICAN JOURNAL OF HYPERTENSION
Transthoracic echocardiographic demonstration of massive pulmonary thrombus caused by protein C deficiency
JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY
Screening for risk factors for thrombosis using a new generation of assaysdeveloped to evaluate the functionality of the protein C anticoagulant pathway
HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA
Severe hemorrhagic complication due to acquired factor V inhibitor after single exposure to bovine thrombin product
JOURNAL OF CARDIAC SURGERY
Prevalence of factor V Leiden and prothrombin variant G20210A in patients age < 50 years with no significant stenoses at angiography three to four weeks after myocardial infarction
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
The prevalence of Factor V Leiden as a risk factor for venous thromboembolism in the population of North-Western Greece
INTERNATIONAL ANGIOLOGY
Arg485Lys polymorphism of factor V increases the risk of coronary artery disease in a Chinese population
CHINESE MEDICAL JOURNAL
Prevalence of the G1691A mutation in the factor V gene (factor V Leiden) and the G20210A prothrombin gene mutation in the Thai population
AMERICAN JOURNAL OF HEMATOLOGY
The prevalence of factor V R506Q mutation-Leiden among apparently healthy Lebanese
AMERICAN JOURNAL OF HEMATOLOGY
An assay to quantify the two plasma isoforms of Factor V
THROMBOSIS AND HAEMOSTASIS
The HR2 haplotype of factor V is not associated with the risk of myocardial infarction
THROMBOSIS AND HAEMOSTASIS
Prothrombin activation is increased among asymptomatic carriers of the prothrombin G20210A and factor V Arg506Gln mutations
THROMBOSIS AND HAEMOSTASIS
Prevalence of factor V Leiden in patients with myocardial infarction and normal coronary angiography
THROMBOSIS AND HAEMOSTASIS
The HR2 haplotype of factor V: Effects on factor V levels, normalized activated protein C sensitivity ratios and the risk of venous thrombosis
THROMBOSIS AND HAEMOSTASIS
Mutations in the R2 FV gene affect the ratio between the two FV isoforms in plasma
THROMBOSIS AND HAEMOSTASIS
Inherited thrombophilia as a risk factor for the development of ischemic stroke in young adults
THROMBOSIS AND HAEMOSTASIS
Factor II G20210A and factor V G1691A gene mutations and peripheral arterial occlusive disease
THROMBOSIS AND HAEMOSTASIS