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Inhibition of skiA and skiB gene expression ventralizes zebrafish embryos
GENESIS
TGF-beta induces assembly of a Smad2-Smurf2 ubiquitin ligase complex that targets SnoN for degradation
NATURE CELL BIOLOGY
Role of PML and PML-RAR alpha in Mad-mediated transcriptional repression
MOLECULAR CELL
Conserved cardiogenic functions of the multitype zinc-finger proteins: U-shaped and FOG-2
TRENDS IN CARDIOVASCULAR MEDICINE
Structural insights into the mode of action of a pure antiestrogen
STRUCTURE
Molecular cloning and characterization of thyroid hormone receptors in teleost fish
JOURNAL OF MOLECULAR ENDOCRINOLOGY
Increased susceptibility to tumorigenesis of ski-deficient heterozygous mice
ONCOGENE
Retinoid-dependent antagonism of serum response factor transactivation mediated by transcriptional coactivator proteins
ONCOGENE
Sut1p interaction with Cyc8p(Ssn6p) relieves hypoxic genes from Cyc8p-Tup1p repression in Saccharomyces cerevisiae
MOLECULAR MICROBIOLOGY
RcoA has pleiotropic effects on Aspergillus nidulans cellular development
MOLECULAR MICROBIOLOGY
Groucho mediates a Ci-independent mechanism of hedgehog repression in the anterior wing pouch
DEVELOPMENT
Difference in XTcf-3 dependency accounts for change in response to beta-catenin-mediated Wnt signalling in Xenopus blastula
DEVELOPMENT
Groucho augments the repression of multiple Even skipped target genes in establishing parasegment boundaries
DEVELOPMENT
Identification and localization of M-CoREST (1A13), a mouse homologue of the human transcriptional co-repressor CoREST, in the developing mouse CNS
MECHANISMS OF DEVELOPMENT
Sharp, an inducible cofactor that integrates nuclear receptor repression and activation
GENES & DEVELOPMENT
Human immunodeficiency virus type 1 Tat binding protein-1 is a transcriptional coactivator specific for TR
MOLECULAR ENDOCRINOLOGY
Two distinct nuclear receptor-interaction domains and CREB-binding protein-dependent transactivation function of activating signal cointegrator-2
MOLECULAR ENDOCRINOLOGY
5 ' TG3 ' interacting factor interacts with Sin3A and represses AR-mediated transcription
MOLECULAR ENDOCRINOLOGY
Mutations at the boundary of the hinge and ligand binding domain of the androgen receptor confer increased transactivation function
MOLECULAR ENDOCRINOLOGY
Class II histone deacetylases: Structure, function, and regulation
BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE
DNA-binding properties of the ecdysteroid receptor-complex (EcR/USP) of the epithelial cell line from Chironomus tentans
ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY
The role of hinge domain in heterodimerization and specific DNA recognition by nuclear receptors
MOLECULAR AND CELLULAR ENDOCRINOLOGY
Cell type-specific roles of histone deacetylase in TR ligand-independent transcriptional repression
MOLECULAR AND CELLULAR ENDOCRINOLOGY
Determinants of CoRNR-dependent repression complex assembly on nuclear hormone receptors
MOLECULAR AND CELLULAR BIOLOGY
A novel GATA factor transcriptionally represses yolk protein precursor genes in the mosquito Aedes aegypti via interaction with the CtBP corepressor
MOLECULAR AND CELLULAR BIOLOGY
Functional interaction of STAT5 and nuclear receptor co-repressor SMRT: implications in negative regulation of STAT5-dependent transcription
EMBO JOURNAL
NRG1, a repressor of filamentous growth in C.albicans, is down-regulated during filament induction
EMBO JOURNAL
Complexities of androgen action
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
An unliganded thyroid hormone receptor causes severe neurological dysfunction
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Transcriptional regulation of the Saccharomyces cerevisiae amino acid permease gene BAP2
MOLECULAR AND GENERAL GENETICS
Retinoic acid and vitamin D-3 powerfully inhibit in vitro leptin secretionby human adipose tissue
JOURNAL OF ENDOCRINOLOGY
Metabolic and cellular analysis of alopecia in vitamin D receptor knockoutmice
JOURNAL OF CLINICAL INVESTIGATION
Thyroid hormone response element sequence and the recruitment of retinoid X receptors for thyroid hormone responsiveness
JOURNAL OF BIOLOGICAL CHEMISTRY
Coregulator codes of transcriptional regulation by nuclear receptors
JOURNAL OF BIOLOGICAL CHEMISTRY
Human HDAC7 histone deacetylase activity is associated with HDAC3 in vivo
JOURNAL OF BIOLOGICAL CHEMISTRY
The modular nature of histone deacetylase HDAC4 confers phosphorylation-dependent intracellular trafficking
JOURNAL OF BIOLOGICAL CHEMISTRY
The ski protein family is required for MeCP2-mediated transcriptional repression
JOURNAL OF BIOLOGICAL CHEMISTRY
Forkhead homologue in rhabdomyosarcoma functions as a bifunctional nuclearreceptor-interacting protein with both coactivator and corepressor functions
JOURNAL OF BIOLOGICAL CHEMISTRY
Role of retinoid receptor coactivator pockets in cofactor recruitment and transcriptional regulation
JOURNAL OF BIOLOGICAL CHEMISTRY
Ski-interacting protein interacts with Smad proteins to augment transforming growth factor-beta-dependent transcription
JOURNAL OF BIOLOGICAL CHEMISTRY
Silencing mediator for retinoid and thyroid hormone receptors interacts with octamer transcription factor-1 and acts as a transcriptional repressor
JOURNAL OF BIOLOGICAL CHEMISTRY
Functional knockout of the corepressor CtBP by the second exon of adenovirus E1A relieves repression of transcription
EXPERIMENTAL CELL RESEARCH
Identification of an element within the promoter of human selenoprotein P responsive to transforming growth factor-beta
EUROPEAN JOURNAL OF BIOCHEMISTRY
Perspective: Female steroid hormone action
ENDOCRINOLOGY
Cytoplasmic localization of the oncogenic protein ski in human cutaneous melanomas in vivo: Functional implications for transforming growth factor beta signaling
CANCER RESEARCH
Localization of nuclear coactivators p300 and steroid receptor coactivator1 in the rat hippocampus
BRAIN RESEARCH
The corepressor CtBP interacts with Evi-1 to repress transforming growth factor beta signaling
BLOOD
Transcriptional activation of the nuclear receptor corepressor RIP140 by retinoic acid: A potential negative-feedback regulatory mechanism
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Acquisition of oncogenic potential by RAR chimeras in acute promyelocytic leukemia through formation of homodimers
MOLECULAR CELL
Histone acetylation modifiers in the pathogenesis of malignant disease
MOLECULAR MEDICINE
Gene regulation by thyroid hormone
TRENDS IN ENDOCRINOLOGY AND METABOLISM
Development of peptide antagonists that target estrogen receptor-cofactor interactions
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
The RXR ortholog USP suppresses early metamorphic processes in Drosophila in the absence of ecdysteroids
DEVELOPMENT
FOG acts as a repressor of red blood cell development in Xenopus
DEVELOPMENT
VDR-Alien: a novel, DNA-selective vitamin D-3 receptor-corepressor partnership
FASEB JOURNAL
Relief of gene repression by Torso RTK signaling: role of capicua in Drosophila terminal and dorsoventral patterning
GENES & DEVELOPMENT
Structural basis for autorepression of retinoid X receptor by tetramer formation and the AF-2 helix
GENES & DEVELOPMENT
Crucial role of the H11-H12 loop in stabilizing the active conformation ofthe human mineralocorticoid receptor
MOLECULAR ENDOCRINOLOGY
Activating protein-1, nuclear factor-kappa B, and serum response factor asnovel target molecules of the cancer-amplified transcription coactivator ASC-2
MOLECULAR ENDOCRINOLOGY
Structure-function analysis of the Rev-erbA and RVR ligand-binding domainsreveals a large hydrophobic surface that mediates corepressor binding and a ligand cavity occupied by side chains
MOLECULAR ENDOCRINOLOGY
Silencing subdomains of v-ErbA interact cooperatively with corepressors: Involvement of helices 5/6
MOLECULAR ENDOCRINOLOGY
ARIP3 (androgen receptor-interacting protein 3) and other PIAS (protein inhibitor of activated STAT) proteins differ in their ability to modulate steroid receptor-dependent transcriptional activation
MOLECULAR ENDOCRINOLOGY
A synthetic triterpenoid, 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO), is a ligand for the peroxisome proliferator-activated receptor gamma
MOLECULAR ENDOCRINOLOGY
The impact of differential binding of wild-type RAR alpha, PML-, PLZF- andNPM-RAR alpha fusion proteins towards transcriptional co-activator, RIP-140, on retinoic acid responses in acute promyelocytic leukemia
LEUKEMIA
Groucho/TLE family proteins and transcriptional repression
GENE
The SRC family of nuclear receptor coactivators
GENE
Analysis of Groucho-histone interactions suggests mechanistic similaritiesbetween Groucho- and Tup1-mediated repression
NUCLEIC ACIDS RESEARCH
Expression of thyroid hormone receptors is disturbed in human renal clear cell carcinoma
CANCER LETTERS
Alterations in retinoid X receptor-alpha expression contribute to cell-type dependent differences in thyroid hormone regulation of malic enzyme transcription
MOLECULAR AND CELLULAR ENDOCRINOLOGY
Ability of the glucocorticoid modulatory element to modify glucocorticoid receptor transactivation indicates parallel pathways for the expression of glucocorticoid modulatory element and glucocorticoid response element activities
MOLECULAR AND CELLULAR ENDOCRINOLOGY
Effect of cyclic adenosine 3 ',5 '-monophosphate and protein kinase A on ligand-dependent transactivation via the vitamin D receptor
MOLECULAR AND CELLULAR ENDOCRINOLOGY
Resistance to thyroid hormone (RTH) syndrome reveals novel determinants regulating interaction of T3 receptor with corepressor
MOLECULAR AND CELLULAR ENDOCRINOLOGY
Transcriptional repression by nuclear receptors: mechanisms and role in disease
BIOCHEMICAL SOCIETY TRANSACTIONS
p300 requires its histone acetyltransferase activity and SRC-1 interactiondomain to facilitate thyroid hormone receptor activation in chromatin
MOLECULAR AND CELLULAR BIOLOGY
BRG-1 is recruited to estrogen-responsive promoters and cooperates with factors involved in histone acetylation
MOLECULAR AND CELLULAR BIOLOGY
dCtBP-dependent and -independent repression activities of the Drosophila knirps protein
MOLECULAR AND CELLULAR BIOLOGY
The SMRT corepressor is regulated by a MEK-1 kinase pathway: Inhibition ofcorepressor function is associated with SMRT phosphorylation and nuclear export
MOLECULAR AND CELLULAR BIOLOGY
The sno gene, which encodes a component of the histone deacetylase complex, acts as a tumor suppressor in mice
EMBO JOURNAL
Nuclear receptor binding factor-2 (NRBF-2), a possible gene activator protein interacting with nuclear hormone receptors
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION
Allosteric effects of Pit-1 DNA sites on long-term repression in cell typespecification
SCIENCE
Differential ligand-dependent protein-protein interactions between nuclearreceptors and a neuronal-specific cofactor
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Very strong correlation between dominant negative activities of mutant thyroid hormone receptors and their binding avidity for corepressor SMRT
JOURNAL OF ENDOCRINOLOGY
Differences between the silencing-related properties of the extreme carboxyl-terminal regions of thyroid hormone receptors alpha 1 and beta 1
JOURNAL OF ENDOCRINOLOGY
Tissue-specific regulation of thyroid hormone receptor mRNA isoforms and target gene proteins in domestic ducks
JOURNAL OF ENDOCRINOLOGY
A dominant-negative peroxisome proliferator-activated receptor gamma (PPARgamma) mutant is a constitutive repressor and inhibits PPAR gamma-mediatedadipogenesis
JOURNAL OF BIOLOGICAL CHEMISTRY
Differential mechanisms of nuclear receptor regulation by receptor-associated coactivator 3
JOURNAL OF BIOLOGICAL CHEMISTRY
Analysis of estrogen receptor interaction with a repressor of estrogen receptor activity (REA) and the regulation of estrogen receptor transcriptional activity by REA
JOURNAL OF BIOLOGICAL CHEMISTRY
Characterization of the repressor function of the nuclear orphan receptor retinoid receptor-related testis-associated receptor/germ cell nuclear factor
JOURNAL OF BIOLOGICAL CHEMISTRY
Mutations in retinoid X receptor that impair heterodimerization with specific nuclear hormone receptor
JOURNAL OF BIOLOGICAL CHEMISTRY
Thyroid hormone-independent interaction between the thyroid hormone receptor beta 2 amino terminus and coactivators
JOURNAL OF BIOLOGICAL CHEMISTRY
A functionally conserved N-terminal domain of the friend of GATA-2 (FOG-2)protein represses GATA4-dependent transcription
JOURNAL OF BIOLOGICAL CHEMISTRY
Ikaros interactions with CtBP reveal a repression mechanism that is independent of histone deacetylase activity
JOURNAL OF BIOLOGICAL CHEMISTRY
Isolation and characterization of peroxisome proliferator-activated receptor (PPAR) interacting protein (PRIP) as a coactivator for PPAR
JOURNAL OF BIOLOGICAL CHEMISTRY
The human transcription factor IID subunit human TATA-binding protein-associated factor 28 interacts in a ligand-reversible manner with the vitamin D-3 and thyroid hormone receptors
JOURNAL OF BIOLOGICAL CHEMISTRY
Characterization of the N-terminal domain of the yeast transcriptional repressor Tup1 - Proposal for an association model of the repressor complex Tup1 center dot Ssn6
JOURNAL OF BIOLOGICAL CHEMISTRY
Interaction of the corepressor Alien with DAX-1 is abrogated by mutations of DAX-1 involved in adrenal hypoplasia congenita
JOURNAL OF BIOLOGICAL CHEMISTRY
Retinoic acid stimulation of the human surfactant protein B promoter is thyroid transcription factor 1 site-dependent
JOURNAL OF BIOLOGICAL CHEMISTRY
Identification of residues in the TPR domain of Ssn6 responsible for interaction with the Tup1 protein
FEBS LETTERS
Kheper, a novel ZFH/delta EF1 family member, regulates the development of the neuroectoderm of zebrafish (Danio rerio)
DEVELOPMENTAL BIOLOGY
Estrogen receptors in human myeloma cells
CANCER RESEARCH