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Late stent thrombosis without antecedent brachytherapy: Confirmation and treatment with rheolytic thrombectomy
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
Prevention of venous graft sclerosis with clopidogrel and aspirin combinedwith a mesh tubing in a dog model of arteriovenous bypass grafting
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
The effect of a novel glycoprotein IIb/IIIa antagonist, SR 121566A, on platelet aggregation and activation in rhesus monkeys
CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS
The inhibition of oxygen radical release from human neutrophil by resting platelets is reversed by administration of acetylsalicylic acid or clopidogrel
FREE RADICAL RESEARCH
Cilostazol for prevention of thrombosis and restenosis after intracoronarystenting
ANNALS OF PHARMACOTHERAPY
Antiplatelet agents for secondary prevention of ischemic stroke
ANNALS OF PHARMACOTHERAPY
Benefit of ADP receptor antagonists in atherothrombotic patients: New evidence
CEREBROVASCULAR DISEASES
Management practices in carotid stenting
CEREBROVASCULAR DISEASES
Future perspectives for optimizing oral antiplatelet therapy
CEREBROVASCULAR DISEASES
Antiplatelet drugs: How to select them and possibilities of combined treatment
CEREBROVASCULAR DISEASES
Novel tricyclic benzothiazolo[2,3-c]thiadiazine antagonists of the platelet ADP receptor (P2Y(12))
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Deaggregation is an integral component of the response of platelets to ADPin vitro: kinetic studies of literature and original data
PLATELETS
The balance of concurrent aggregation and deaggregation processes in platelets is linked to differential occupancy of ADP receptor subtypes
PLATELETS
Activation of G(i)-coupled receptors releases a tonic state of inhibited platelet aggregation
PLATELETS
Bleeding complications in combined treatment with clopidrogel and low-doseheparin in stroke patients
PERFUSION
Ticlopidine-associated thrombotic thrombocytopenic purpura with an IgG-type inhibitor to von Willebrand factor-cleaving protease activity
INTERNATIONAL JOURNAL OF HEMATOLOGY
The use of antiplatelet agents in acute cardiac care
CRITICAL CARE CLINICS
Incidence of thrombotic occlusion and major adverse cardiac events betweentwo and four weeks after coronary stent placement: Analysis of 5,678 patients with a four-week ticlopidine regimen
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
Ticlopidine versus aspirin after myocardial infarction (STAMI) trial
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
The platelet ADP receptors
HAEMATOLOGICA
Radiation-induced glomerular thrombus formation and nephropathy are not prevented by the ADP receptor antagonist clopidogrel
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
Coronary stent thrombosis: Insights from the porcine coronary stent model
THROMBOSIS AND HAEMOSTASIS
Differential involvement of the P2Y(1) and P2Y(T) receptors in the morphological changes of platelet aggregation
THROMBOSIS AND HAEMOSTASIS
Open multicentre study of the P-2T receptor antagonist AR-C69931MX assessing safety, tolerability and activity in patients with acute coronary syndromes
THROMBOSIS AND HAEMOSTASIS
Recovery of platelet function after discontinuation of clopidogrel treatment in healthy volunteers
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
Clopidogrel in acute coronary syndromes with non-ST elevation. Clinical implications of CURE trial
REVISTA ESPANOLA DE CARDIOLOGIA
Current perspectives on British use of adjunctive therapies during coronary interventions
INTERNATIONAL JOURNAL OF CARDIOLOGY
Eptifibatide and abciximab exhibit equivalent antiplatelet efficacy in an experimental model of stenting in both healthy volunteers and patients withcoronary artery disease
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
Methods and systems to detect adverse drug reactions in hospitals
DRUG SAFETY
Identification of the platelet ADP receptor targeted by antithrombotic drugs
NATURE
Molecular identification and characterization of the platelet ADP receptortargeted by thienopyridine antithrombotic drugs
JOURNAL OF CLINICAL INVESTIGATION
Inhibition of platelet function by administration of MRS2179, a P2Y(1) receptor antagonist
EUROPEAN JOURNAL OF PHARMACOLOGY
Key role of the P2Y(1) receptor in tissue factor-Induced thrombin-dependent acute thromboembolism - Studies in P2Y(1)-knockout mice and mice treated with a P2Y(1) antagonist
CIRCULATION
Ticlopidine pretreatment before coronary stenting is associated with sustained decrease in adverse cardiac events - Data from the Evaluation of Platelet IIb/IIIa Inhibitor for Stenting (EPISTENT) trial
CIRCULATION
Clopidogrel and side effects
CARDIOLOGY
Effects of combining three different antiplatelet agents on platelets and leukocytes in whole blood in vitro
BRITISH JOURNAL OF PHARMACOLOGY
Antiplatelet action of R-99224, an active metabolite of a novel thienopyridine-type G(i)-linked P2T antagonist, CS-747
BRITISH JOURNAL OF PHARMACOLOGY
P2Y(12), a new platelet ADP receptor, target of clopidogrel
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
New antiplatelet drugs
ANAESTHESIST
Does ticlopidine reduce reocclusion and other adverse events after successful balloon angioplasty of occluded coronary arteries? Results from the Total Occlusion Study of Canada (TOSCA)
AMERICAN HEART JOURNAL
Incidence of thrombocytopenia following coronary stent placement using abciximab plus clopidogrel or ticlopidine
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
Combination therapy with clopidogrel and aspirin after coronary stenting
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
Adenosine diphosphate receptor antagonists: from pharmacology to clinical practice
EUROPEAN HEART JOURNAL SUPPLEMENTS
Rationale, design and organization of the Second Chinese Cardiac Study (CCS-2): a randomized trial of clopidogrel plus aspirin, and of metoprolol, among patients with suspected acute myocardial infarction
JOURNAL OF CARDIOVASCULAR RISK
Cyanothioacetamide in heterocyclic chemistry: Synthesis of thiopyran, pyridinethione, thienopyridine, pyridothienotriazine and pyridothienopyrimidinederivatives
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
Update on clinical trials of antiplatelet therapy for cerebrovascular diseases
CEREBROVASCULAR DISEASES
Antiplatelet agents in stroke prevention - Combination therapy: Present and future
CEREBROVASCULAR DISEASES
Antiplatelet agents for stroke prevention
CEREBROVASCULAR DISEASES
Clopidogrel and coronary stenting: What is the next question?
JOURNAL OF THROMBOSIS AND THROMBOLYSIS
A pharmacodynamic study of clopidogrel in chronic hemodialysis patients
JOURNAL OF THROMBOSIS AND THROMBOLYSIS
Platelet surface physiology and its importance in pharmacotherapy design and development: The adenosine diphosphate receptor antagonists
JOURNAL OF THROMBOSIS AND THROMBOLYSIS
Thrombolysis by thienopyridines and their congeners
JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
ortho-metalation/chlorination of benzoic acid derivatives: Preparation of [benzene-U-C-13]-rac-Clopidogrel ([benzene-U-C-13]-rac-SR25990C).
JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS
Identification and biological activity of the active metabolite of clopidogrel
THROMBOSIS AND HAEMOSTASIS
Desensitization of the platelet aggregation response to ADP: Differential down-regulation of the P2Y(1) and P2cyc receptors
THROMBOSIS AND HAEMOSTASIS
Pharmacokinetics and pharmacodynamics of sibrafiban alone or in combination with ticlopidine and aspirin
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
Impediment of the cellular immune response under treatment with ticlopidine in aortic valve endocarditis caused by Staphylococcus aureus
ZEITSCHRIFT FUR KARDIOLOGIE
Characteristics of rat platelets and relative contributions of platelets and blood coagulation to haemostasis
FOOD AND CHEMICAL TOXICOLOGY
Coronary stent implantation: a panacea for the interventional cardiologist?
EUROPEAN HEART JOURNAL
Primary stenting for high-grade basilar artery stenosis
AMERICAN JOURNAL OF NEURORADIOLOGY
Abciximab rescue in acute carotid stent thrombosis
AMERICAN JOURNAL OF NEURORADIOLOGY
Optimizing antiplatelet therapy in coronary interventions
CLINICAL CARDIOLOGY
Value of antiplatelet therapy in preventing thrombotic events in generalized vascular disease
CLINICAL CARDIOLOGY
The future of antiplatelet therapy: Optimizing management in patients withacute coronary syndrome
CLINICAL CARDIOLOGY
Prevention and treatment of thromboembolic and ischemic complications associated with endovascular procedures: Part I - Pathophysiological and pharmacological features
NEUROSURGERY
Increased expression of P-selectin in patients with chronic atrial fibrillation
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
Very slow chiral inversion of clopidogrel in rats: A pharmacokinetic and mechanistic investigation
DRUG METABOLISM AND DISPOSITION
Antithrombotic properties of RWJ-50353, a potent and novel thrombin inhibitor
THROMBOSIS RESEARCH
Gastroduodenal tolerance of 75 mg clopidogrel versus 325 mg aspirin in healthy volunteers - A gastroscopic study
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
Carotid endarteriectomy and carotic stenting. Pilot study of a prospective, randomized and controlled comparison
RADIOLOGE
Advances in interventional cardiology - Beyond the balloon
NURSING CLINICS OF NORTH AMERICA
Unstable angina. Short term treatment with clopidogrel with the use of a loading dose: Effect on ADP-induced platelet aggregation
KARDIOLOGIYA
Changes in local cerebral blood flow in photochemically induced thromboticocclusion model in rats
EUROPEAN JOURNAL OF PHARMACOLOGY
Clopidogrel - A review of its use in the prevention of atherothrombosis
DRUGS
A randomized comparison of clopidogrel and aspirin versus ticlopidine and aspirin after the placement of coronary-artery stents
CIRCULATION
The in vivo pharmacological profile of CS-747, a novel antiplatelet agent with platelet ADP receptor antagonist properties
BRITISH JOURNAL OF PHARMACOLOGY
ADP can induce aggregation of human platelets via both P2Y(1) and P-2T receptors
BRITISH JOURNAL OF PHARMACOLOGY
Antiplatelet agents in cardiology: The choice of therapy
ANNALS OF THORACIC SURGERY
Antiplatelet agents in spinal anesthesia
ANAESTHESIST
Interventions in cardiology: What does and does not work
AMERICAN JOURNAL OF CARDIOLOGY
Unifying concept of arterial vascular disease
EUROPEAN HEART JOURNAL SUPPLEMENTS
Biochemical and pharmacological properties of clopidogrel: a new ADP receptor antagonist
EUROPEAN HEART JOURNAL SUPPLEMENTS
ADP receptors and clinical bleeding disorders
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
Successful use of clopidogrel for cerebrovascular accident in a patient with suspected ticlopidine-induced hepatotoxicity
ANNALS OF PHARMACOTHERAPY
Clopidogrel: The future choice for preventing platelet activation during coronary stenting?
PHARMACOLOGICAL RESEARCH
Inhalation of nitric oxide inhibits ADP-induced platelet aggregation and alpha-granule release
PLATELETS
Thienopyridines: Effects on cultured endothelial cells
JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
Antiplatelet activity of clopidogrel in coronary artery bypass graft surgery patients
THROMBOSIS AND HAEMOSTASIS
The P2Y(1) receptor is normal in a patient presenting a severe deficiency of ADP-induced platelet aggregation - Further evidence for a distinct P2 receptor responsible for adenylyl cyclase inhibition
THROMBOSIS AND HAEMOSTASIS
Effects of clopidogrel on platelet activation and coagulation of non-anticoagulated rat blood under high shear stress
HAEMOSTASIS
Unifying concept of arterial vascular disease
EUROPEAN HEART JOURNAL
Biochemical and pharmacological properties of clopidogrel: a new ADP receptor antagonist
EUROPEAN HEART JOURNAL
Platelet-endothelial interactions in atherothrombotic disease: Therapeuticimplications
CLINICAL CARDIOLOGY
Interspecies comparison of the antiplatelet, antithrombotic, and hemorrhagic effects of SR 121566A, a novel nonpeptide GP IIb IIIa antagonist
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
Clopidogrel loading dose regimens: Kinetic profile of pharmacodynamic response in healthy subjects
SEMINARS IN THROMBOSIS AND HEMOSTASIS
Long-term activity of clopidogrel: A three-month appraisal in healthy volunteers
SEMINARS IN THROMBOSIS AND HEMOSTASIS
Pharmacokinetics of clopidogrel
SEMINARS IN THROMBOSIS AND HEMOSTASIS
Pharmacokinetic profile of C-14-labeled clopidogrel
SEMINARS IN THROMBOSIS AND HEMOSTASIS
Clopidogrel and drug metabolism: Absence of effect on hepatic enzymes in healthy volunteers
SEMINARS IN THROMBOSIS AND HEMOSTASIS
Clopidogrel bioavailability: Absence of influence of food or antacids
SEMINARS IN THROMBOSIS AND HEMOSTASIS