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Development of progressive pulmonary interstitial and intra-alveolar cholesterol granulomas (PICG) associated with therapy-resistant chronic systemicjuvenile arthritis (CJA)
PEDIATRIC PULMONOLOGY
Synthesis of novel potential antitumor agents: 2,6-dimethoxyhydroquinone-3-mercapto-acetyl peptide conjugates
PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY
Bcl-2 antisense oligonucleotides enhance the cytotoxicity of Chlorambucil in B-cell chronic lymphocytic leukaemia cells
LEUKEMIA & LYMPHOMA
Does intensive treatment with high dose chlorambucil and prednisone as first line and cladribine as second line influence the survival of the patients with chronic lymphocytic leukemia?
LEUKEMIA & LYMPHOMA
Severe bone marrow failure associated with the use of alternating steroid with chlorambucil in lupus membranous nephropathy in Chinese
LUPUS
Management of systemic lupus erythematosus (SLE)
CLINICAL AND EXPERIMENTAL ALLERGY
Treatment of membranous nephropathy
NEPHROLOGY DIALYSIS TRANSPLANTATION
A meta-analysis of cytotoxic treatment for frequently relapsing nephrotic syndrome in children
PEDIATRIC NEPHROLOGY
Prediction of subsequent relapse in children with steroid-sensitive nephrotic syndrome
PEDIATRIC NEPHROLOGY
A phase II study of sequential combination chemotherapy with cyclophosphamide, prednisone, and 2-chlorodeoxyadenosine in previously untreated patients with chronic lymphocytic leukemia
LEUKEMIA
Cladribine combined with cyclophosphamide and mitoxantrone as front-line therapy in chronic lymphocytic leukemia
LEUKEMIA
Results of the fludarabine and cyclophosphamide combination regimen in chronic lymphocytic leukemia
JOURNAL OF CLINICAL ONCOLOGY
Differences in the intracellular distribution of acid-sensitive doxorubicin-protein conjugates in comparison to free and liposomal formulated doxorubicin as shown by confocal microscopy
PHARMACEUTICAL RESEARCH
UCN-01 induces cytotoxicity toward human CLL cells through a p53-independent mechanism
EXPERIMENTAL HEMATOLOGY
Short- and long-term efficacy of oral cyclophosphamide and steroids in patients with membranous nephropathy and renal insufficiency
CLINICAL NEPHROLOGY
A systematic overview of chemotherapy effects in B-cell chronic lymphocytic leukaemia
ACTA ONCOLOGICA
Urinary excretion of IgG and alpha(1)-microglobulin predicts clinical course better than extent of proteinuria in membranous nephropathy
AMERICAN JOURNAL OF KIDNEY DISEASES
Esters of chlorambucil with 2-substituted 1,4-dihydroxy-9,10-anthraquinones as multifunctional anticancer agents
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Immunosuppressive agents in childhood nephrotic syndrome: A meta-analysis of randomized controlled trials
KIDNEY INTERNATIONAL
Cyclosporine in patients with steroid-resistant membranous nephropathy: A randomized trial
KIDNEY INTERNATIONAL
Fludarabine for chronic lymphocytic leukemia. Reply
NEW ENGLAND JOURNAL OF MEDICINE
Pneumonias in patients with chronic lymphocytic leukemia. Study of 30 episodes
MEDICINA CLINICA
Toward polymeric anticancer drug cocktails from ring-opening metathesis polymerization
MACROMOLECULES
Novel peptide conjugates for tumor-specific chemotherapy
JOURNAL OF MEDICINAL CHEMISTRY
Ocular concerns in juvenile rheumatoid arthritis
INTERNATIONAL OPHTHALMOLOGY CLINICS
Mononuclear tetraamineplatinum(II) complexes: Synthesis, anticancer activity, DNA binding, and cellular uptake
HELVETICA CHIMICA ACTA
Primary low-grade B cell non-Hodgkin's lymphoma of MALT type simultaneously arising in the colon and in the lung - Report of a case
DISEASES OF THE COLON & RECTUM
The cell transmembrane pH gradient in tumors enhances cytotoxicity of specific weak acid chemotherapeutics
CANCER RESEARCH
Autologous plasma activates Akt/protein kinase B and enhances basal survival and resistance to DNA damage-induced apoptosis in B-chronic lymphocytic leukaemia cells
BRITISH JOURNAL OF HAEMATOLOGY
Induction of apoptosis by the ADEPT agent ZD2767: comparison with the classical nitrogen mustard chlorambucil and a monofunctional ZD2767 analogue
BRITISH JOURNAL OF CANCER
Randomized comparison of fludarabine, CAP, and ChOP in 938 previously untreated stage B and C chronic lymphocytic leukemia patients
BLOOD
Chronic lymphocytic leukemia - Part 2: Treatment
DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT
Potential anticancer drugs, 4 - Glycosyl glycerol derivatives as drug carrier system. Stereoselective synthesis of epoxyalkyl N-acyl-beta-D-glucopyranosides and their reactivity with nucleophiles
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Mutations induced by some DNA minor groove binding alkylators in AS52 Chinese hamster cells
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
Polymyxin permeabilization as a tool to investigate cytotoxicity of therapeutic aromatic alkylators in DNA repair-deficient Escherichia coli strains
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
Management of membranous nephropathy
NEPHROLOGY
Management of chronic lymphocytic leukaemia
DRUGS & AGING
Elementary clinical decision analysis in evidence-based nephrology
JOURNAL OF NEPHROLOGY
The relationship between intracellular and extracellular pH in spontaneouscanine tumors
CLINICAL CANCER RESEARCH
In vitro and in vivo efficacy of acid-sensitive transferrin and albumin doxorubicin conjugates in a human xenograft panel and in the MDA-MB-435 mammacarcinoma model
JOURNAL OF DRUG TARGETING
A morphological study of the effect of chlorambucil during the S and G2 phases of the cell cycle of synchronized HEp-2 cancer cell populations using computerized morphometry
MICRON
Consolidation therapy with high-dose cyclophosphamide improves the qualityof response in patients with chronic lymphocytic leukemia treated with fludarabine as induction therapy
LEUKEMIA
Phase I/II study of 2-chloro-2 '-deoxyadenosine with cyclophosphamide in patients with pretreated B cell chronic lymphocytic leukemia and indolent. non-Hodgkin's lymphoma
LEUKEMIA
Treatment of idiopathic membranous nephropathy (IMN)
RENAL FAILURE
Treatment of idiopathic membranous glomerulonephritis
PRESSE MEDICALE
Long-term follow-up after fludarabine treatment in pretreated patients with chronic lymphocytic leukemia
HAEMATOLOGICA
Tris lipidation: A chemically flexible technology for modifying the delivery of drugs and genes
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
Glutathione-related factors are not correlated with sensitivity of human tumour cells to actinomycin D
CANCER LETTERS
AT(1)-receptor blocker in idopathic chronic membranous glomerulonephritis
NIEREN-UND HOCHDRUCKKRANKHEITEN
Use of mycophenolate mofetil in resistant membranous nephropathy
AMERICAN JOURNAL OF KIDNEY DISEASES
Chlorambucil-induced acute hepatic failure in a patient with membranous nephropathy
AMERICAN JOURNAL OF KIDNEY DISEASES
The treatment of idiopathic membranous nephropathy
SEMINARS IN NEPHROLOGY
Steroid and immunosuppressive treatment in idiopathic membranous glomerulonephritis
NEFROLOGIA
Intracellular sequestration of anti-tumor drugs by metallothionein
CELLULAR AND MOLECULAR BIOLOGY
Bcl-2 and Bax expression and chlorambucil-induced apoptosis in the T-cellsand leukaemic B-cells of untreated B-cell chronic lymphocytic leukaemia patients
LEUKEMIA RESEARCH
A phase I and II study of pentostatin (Nipent) with cyclophosphamide for previously treated patients with chronic lymphocytic leukemia
SEMINARS IN ONCOLOGY
Molecular dynamics simulation of metallothionein-drug complexes
DRUG METABOLISM AND DISPOSITION
A reappraisal of the role of chlorambucil in patients with end stage ovarian cancer who have previously been treated with platinum regimens
SCOTTISH MEDICAL JOURNAL
Dexamethasone does not enhance antileukemic activity of cladribine in micewith leukemias L1210 and P388
NEOPLASMA
Cellular response to a glutathione S-transferase P1-1 activated prodrug
MOLECULAR PHARMACOLOGY
A comparison of typical and atypical forms with an emphasis on time to remission. Case review of 86 patients from 2 institutions
MEDICINE
The influence of coordinate overexpression of glutathione phase II detoxification gene products on drug resistance
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
The effect of polyamine homologation on the transport and cytotoxicity properties of polyamine-(DNA-intercalator) conjugates
JOURNAL OF ORGANIC CHEMISTRY
A novel macromolecular prodrug concept exploiting endogenous serum albuminas a drug carrier for cancer chemotherapy
JOURNAL OF MEDICINAL CHEMISTRY
Prolidase-activated prodrug for cancer chemotherapy - Cytotoxic activity of proline analogue of chlorambucil in breast cancer MCF-7 cells
FARMACO
Transcriptional blockages in a cell-free system by sequence-selective DNA alkylating agents
CHEMICO-BIOLOGICAL INTERACTIONS
Waldenstrom's macroglobulinaemia: a prospective study comparing daily withintermittent oral chlorambucil
BRITISH JOURNAL OF HAEMATOLOGY
Cladribine with or without prednisone in the treatment of previously treated and untreated B-cell chronic lymphocytic leukaemia - updated results of the multicentre study of 378 patients
BRITISH JOURNAL OF HAEMATOLOGY
Fludarabine and cyclophosphamide with filgrastim support in patients with previously untreated indolent lymphoid malignancies
BLOOD
Activity of allelic variants of Pi class human glutathione S-transferase toward chlorambucil
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
A 65-year-old man with chronic back pain and shortness of breath - Renal amyloidosis.
AMERICAN JOURNAL OF THE MEDICAL SCIENCES
Long-term toxicity of immune suppression in juvenile rheumatic diseases
RHEUMATOLOGY
Rapid determination of the anti-cancer drug chlorambucil (Leukeran (TM)) and its phenyl acetic acid mustard metabolite in human serum and plasma by automated solid-phase extraction and liquid chromatography-tandem mass spectrometry
JOURNAL OF CHROMATOGRAPHY B
The place of cyclosporin in the management of primary nephrotic syndrome
BIODRUGS
Primary glomerulonephritides with nephrotic syndrome. Limitations of therapy in adult patients
JOURNAL OF NEPHROLOGY
Probing the mechanism of transport and compartmentalisation of polyamines in mammalian cells
CHEMISTRY & BIOLOGY
Immunosuppressive therapy in primary glomerulonephritis
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION
GSH, GSH-related enzymes and GS-X pump in relation to sensitivity of humantumor cell lines to chlorambucil and adriamycin
INTERNATIONAL JOURNAL OF ONCOLOGY
Acid-sensitive polyethylene glycol conjugates of doxorubicin: Preparation,in vitro efficacy and intracellular distribution
BIOORGANIC & MEDICINAL CHEMISTRY
Chlorambucil-induced inappropriate antidiuresis in a man with chronic lymphocytic leukemia
ANNALS OF HEMATOLOGY
The anticancer drug chlorambucil interacts with the human erythrocyte membrane and model phospholipid bilayers
ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES
Retroperitoneal fibrosis and membranous nephropathy. Improvement of both diseases after treatment with steroids and immunosuppressive agents
NEPHROLOGY DIALYSIS TRANSPLANTATION
Does cyclosporin have a role in the treatment of membranous nephropathy?
NEPHROLOGY DIALYSIS TRANSPLANTATION
Aggressive treatment of severe idiopathic focal segmental glomerulosclerosis
PEDIATRIC NEPHROLOGY
Fludarabine and epirubicin in the treatment of chronic lymphocytic leukaemia: A German multicenter phase II study
ANNALS OF ONCOLOGY
Potentiation of antitumor effects of cyclophosphamide derivatives in B-chronic lymphocytic leukemia cells by 2-chloro-2 '-deoxyadenosine
LEUKEMIA
The effect of chlorambucil upon lysozyme activity
FUNDAMENTAL & CLINICAL PHARMACOLOGY
In vitro drug-induced cytotoxicity predicts clinical response to high-dosechlorambucil in B-cell chronic lymphocytic leukemia
HAEMATOLOGICA
Immunosuppression in uveitis therapy
SPRINGER SEMINARS IN IMMUNOPATHOLOGY
Chlorambucil in severe juvenile chronic arthritis: Longterm followup with special reference to amyloidosis
JOURNAL OF RHEUMATOLOGY
A disease severity scale for systemic sclerosis: Development and testing
JOURNAL OF RHEUMATOLOGY
Generalised granuloma annulare successfully treated with PUVA
CLINICAL AND EXPERIMENTAL DERMATOLOGY
Reactions of 4-bis(2-chloroethyl)aminophenylacetic acid (phenylacetic acidmustard) in physiological solutions
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2
Protecting-group strategies for the synthesis of N-4-substituted and N-1,N-8-disubstituted spermidines, exemplified by hirudonine
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
Phase II study of 2-chlorodeoxyadenosine in combination with chlorambucil in previously untreated B-cell chronic lymphocytic leukemia
AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS
Treatment and long-term follow-up of patients with stage II to III idiopathic membranous nephropathy
AMERICAN JOURNAL OF KIDNEY DISEASES
Does immunosuppression with prednisolone and azathioprine alter the progression of idiopathic membranous nephropathy?
AMERICAN JOURNAL OF KIDNEY DISEASES
Tris and the ready production of drug-fatty acyl conjugates
DRUG DEVELOPMENT RESEARCH
Relapsing membranous nephropathy - Response to therapy of relapses compared to that of the original disease
AMERICAN JOURNAL OF NEPHROLOGY
Low-dose methotrexate in the treatment of severe juvenile rheumatoid arthritis and sarcoid iritis
JOURNAL OF PEDIATRIC OPHTHALMOLOGY & STRABISMUS