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La ricerca find articoli where soggetti phrase all words 'CHK1' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 59 riferimenti
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    1. Luo, Y; Rockow-Magnone, SK; Kroeger, PE; Frost, L; Chen, ZH; Han, EKH; Ng, SC; Simmer, RL; Giranda, VL
      Blocking CHK1 expression induces apoptosis and abrogates the G2 checkpointmechanism

      NEOPLASIA
    2. Alcasabas, AA; Osborn, AJ; Bachant, J; Hu, FH; Werler, PJH; Bousset, K; Furuya, K; Diffley, JFX; Carr, AM; Elledge, SJ
      Mrc1 transduces signals of DNA replication stress to activate Rad53

      NATURE CELL BIOLOGY
    3. Tanaka, K; Russell, P
      Mrc1 channels the DNA replication arrest signal to checkpoint kinase Cds1

      NATURE CELL BIOLOGY
    4. Khanna, KK; Lavin, MF; Jackson, SP; Mulhern, TD
      ATM, a central controller of cellular responses to DNA damage

      CELL DEATH AND DIFFERENTIATION
    5. Griffiths, DJF; Liu, VF; Nurse, P; Wang, TSF
      Role of fission yeast primase catalytic subunit in the replication checkpoint

      MOLECULAR BIOLOGY OF THE CELL
    6. Canman, CE
      Replication checkpoint: Preventing mitotic catastrophe

      CURRENT BIOLOGY
    7. Lopez-Girona, A; Kanoh, J; Russell, P
      Nuclear exclusion of Cdc25 is not required for the DNA damage checkpoint in fission yeast

      CURRENT BIOLOGY
    8. Gentile, M; Ahnstrom, M; Schon, F; Wingren, S
      Candidate tumour suppressor genes at 11q23-q24 in breast cancer: evidence of alterations in PIG8, a gene involved in p53-induced apoptosis

      ONCOGENE
    9. Koniaras, K; Cuddihy, AR; Christopoulos, H; Hogg, A; O'Connell, MJ
      Inhibition of Chk1-dependent G2 DNA damage checkpoint radiosensitizes p53 mutant human cells

      ONCOGENE
    10. Yin, MB; Hapke, G; Guo, B; Azrak, RG; Frank, C; Rustum, YM
      The Chk1-Cdc25C regulation is involved in sensitizing A253 cells to a novel topoisomerase I inhibitor BNP1350 by bax gene transfer

      ONCOGENE
    11. Wang, H; Liu, D; Wang, YC; Qin, J; Elledge, SJ
      Pds1 phosphorylation in response to DNA damage is essential for its DNA damage checkpoint function

      GENES & DEVELOPMENT
    12. Rhind, N; Russell, P
      Roles of the mitotic inhibitors Wee1 and Mik1 in the G(2) DNA damage and replication checkpoints

      MOLECULAR AND CELLULAR BIOLOGY
    13. Tanaka, K; Boddy, MN; Chen, XB; McGowan, CH; Russell, P
      Threonine-11, phosphorylated by Rad3 and ATM in vitro, is required for activation of fission yeast checkpoint kinase Cds1

      MOLECULAR AND CELLULAR BIOLOGY
    14. Luo, Y; Rockow-Magnone, SK; Joseph, MK; Bradner, J; Butler, CC; Tahir, SK; Han, EKH; Ng, SC; Severin, JM; Gubbins, EJ; Reilly, RM; Rueter, A; Simmer, RL; Holzman, TF; Giranda, VL
      Abrogation of G2 checkpoint specifically sensitize p53 defective cells to cancer chemotherapeutic agents

      ANTICANCER RESEARCH
    15. Wan, S; Walworth, NC
      A novel genetic screen identifies checkpoint-defective alleles of Schizosaccharomyces pombe chk1

      CURRENT GENETICS
    16. Bulavin, DV; Higashimoto, Y; Popoff, IJ; Gaarde, WA; Basrur, V; Potapova, O; Appella, E; Fornace, AJ
      Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase

      NATURE
    17. Falck, J; Mailand, N; Syljuasen, RG; Bartek, J; Lukas, J
      The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

      NATURE
    18. Gotoh, T; Ohsumi, K; Matsui, T; Takisawa, H; Kishimoto, T
      Inactivation of the checkpoint kinase Cds1 is dependent on cyclin B-Cdc2 kinase activation at the meiotic G(2)/M-phase transition in Xenopus oocytes

      JOURNAL OF CELL SCIENCE
    19. van Vugt, MATM; Smits, VAJ; Klompmaker, R; Medema, RH
      Inhibition of polo-like kinase-1 by DNA damage occurs in an ATM- or ATR-dependent fashion

      JOURNAL OF BIOLOGICAL CHEMISTRY
    20. Damia, G; Sanchez, Y; Erba, E; Broggini, M
      DNA damage induces p53-dependent down-regulation of hCHK1

      JOURNAL OF BIOLOGICAL CHEMISTRY
    21. Gustafson, MP; Thomas, CF; Rusnak, F; Limper, AH; Leof, EB
      Differential regulation of growth and checkpoint control mediated by a Cdc25 mitotic phosphatase from Pneumocystis carinii

      JOURNAL OF BIOLOGICAL CHEMISTRY
    22. Yu, Q; La Rose, JH; Zhang, HL; Pommier, Y
      Antisense inhibition of Chk2/hCds1 expression attenuates DNA damage-induced S and G2 checkpoints and enhances apoptotic activity in HEK-293 cells

      FEBS LETTERS
    23. Oe, T; Nakajo, N; Katsuragi, Y; Okazaki, K; Sagata, N
      Cytoplasmic occurrence of the Chk1/Cdc25 pathway and regulation of Chk1 inXenopus oocytes

      DEVELOPMENTAL BIOLOGY
    24. Hirose, Y; Berger, MS; Pieper, RO
      Abrogation of the Chk1-mediated G(2) checkpoint pathway potentiates temozolomide-induced toxicity in a p53-independent manner in human glioblastoma cells

      CANCER RESEARCH
    25. Zhang, Z; Huang, CS; Li, JX; Leonard, SS; Lanciotti, R; Butterworth, L; Shi, XL
      Vanadate-induced cell growth regulation and the role of reactive oxygen species

      ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
    26. Yu, KR; Saint, RB; Sullivan, W
      The Grapes checkpoint coordinates nuclear envelope breakdown and chromosome condensation

      NATURE CELL BIOLOGY
    27. Kappas, NC; Savage, P; Chen, KC; Walls, AT; Sible, JC
      Dissection of the XChk1 signaling pathway in Xenopus laevis embryos

      MOLECULAR BIOLOGY OF THE CELL
    28. Guo, ZJ; Dunphy, WG
      Response of Xenopus Cds1 in cell-free extracts to DNA templates with double-stranded ends

      MOLECULAR BIOLOGY OF THE CELL
    29. Guo, ZJ; Kumagai, A; Wang, SX; Dunphy, WG
      Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts

      GENES & DEVELOPMENT
    30. Takai, H; Tominaga, K; Motoyama, N; Minamishima, YA; Nagahama, H; Tsukiyama, T; Ikeda, K; Nakayama, K; Nakanishi, N; Nakayama, K
      Aberrant cell cycle checkpoint function and early embryonic death in Chk1(-/-) mice

      GENES & DEVELOPMENT
    31. Liu, QH; Guntuku, S; Cui, XS; Matsuoka, S; Cortez, D; Tamai, K; Luo, GB; Carattini-Rivera, S; DeMayo, F; Bradley, A; Donehower, LA; Elledge, SJ
      Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint

      GENES & DEVELOPMENT
    32. Caspari, T; Dahlen, M; Kanter-Smoler, G; Lindsay, HD; Hofmann, K; Papadimitriou, K; Sunnerhagen, P; Carr, AM
      Characterization of Schizosaccharomyces pombe Hus1: a PCNA-related proteinthat associates with Rad1 and Rad9

      MOLECULAR AND CELLULAR BIOLOGY
    33. Boddy, MN; Lopez-Girona, A; Shanahan, P; Interthal, H; Heyer, WD; Russell, P
      Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1

      MOLECULAR AND CELLULAR BIOLOGY
    34. Tan, SY; Wang, TSF
      Analysis of fission yeast primase defines the checkpoint responses to aberrant S phase initiation

      MOLECULAR AND CELLULAR BIOLOGY
    35. Moser, BA; Brondello, JM; Baber-Furnari, B; Russell, P
      Mechanism of caffeine-induced checkpoint override in fission yeast

      MOLECULAR AND CELLULAR BIOLOGY
    36. Christensen, PU; Bentley, NJ; Martinho, RG; Nielsen, O; Carr, AM
      Mik1 levels accumulate in S phase and may mediate an intrinsic link between S phase and mitosis

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    37. Griffiths, D; Uchiyama, M; Nurse, P; Wang, TSF
      A novel mutant allele of the chromatin-bound fission yeast checkpoint protein Rad17 separates the DNA structure checkpoints

      JOURNAL OF CELL SCIENCE
    38. Borgne, A; Nurse, P
      The Spd1p S phase inhibitor can activate the DNA replication checkpoint pathway in fission yeast

      JOURNAL OF CELL SCIENCE
    39. Rhind, N; Russell, P
      Chk1 and Cds1: linchpins of the DNA damage and replication checkpoint pathways

      JOURNAL OF CELL SCIENCE
    40. Raleigh, JM; O'Connell, MJ
      The G(2) DNA damage checkpoint targets both Wee1 and Cdc25

      JOURNAL OF CELL SCIENCE
    41. Hutchins, JRA; Hughes, M; Clarke, PR
      Substrate specificity determinants of the checkpoint protein kinase Chk1

      FEBS LETTERS
    42. Jayasree, PR; Kumar, PRM; Nair, RV
      The plasmodia of Physarum polycephalum, an elegant system to demonstrate the importance of genome integrity in traversing the G2/M checkpoint of the cell cycle

      CURRENT SCIENCE
    43. Yamane, K; Tsuruo, T
      Conserved BRCT regions of TopBP1 and of the tumor suppressor BRCA1 bind strand breaks and termini of DNA

      ONCOGENE
    44. Kaneko, Y; Watanabe, N; Morisaki, H; Akita, H; Fujimoto, A; Tominaga, K; Terasawa, M; Tachibana, A; Ikeda, K; Nakanishi, M
      Cell cycle-dependent and ATM-independent expression of human Chk1 kinase

      ONCOGENE
    45. Robertson, GP; Goldberg, EK; Lugo, TG; Fountain, JW
      Functional localization of a melanoma tumor suppressor gene to a small (<=2 Mb) region on 11q23

      ONCOGENE
    46. Chen, P; Gatei, M; O'Connell, MJ; Khanna, KK; Bugg, SJ; Hogg, A; Scott, SP; Hobson, K; Lavin, MF
      Chk1 complements the G2/M checkpoint defect and radiosensitivity of ataxia-telangiectasia cells

      ONCOGENE
    47. Kumagai, A; Dunphy, WG
      Binding of 14-3-3 proteins and nuclear export control the intracellular localization of the mitotic inducer Cdc25

      GENES & DEVELOPMENT
    48. Murakami, H; Nurse, P
      Meiotic DNA replication checkpoint control in fission yeast

      GENES & DEVELOPMENT
    49. Wan, SH; Capasso, H; Walworth, NC
      The topoisomerase I poison camptothecin generates a Chk1-dependent DNA damage checkpoint signal in fission yeast

      YEAST
    50. Zeng, Y; Piwnica-Worms, H
      DNA damage and replication checkpoints in fission yeast require nuclear exclusion of the Cdc25 phosphatase via 14-3-3 binding

      MOLECULAR AND CELLULAR BIOLOGY
    51. Aguda, BD
      A quantitative analysis of the kinetics of the G(2) DNA damage checkpoint system

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    52. Nakajo, N; Oe, T; Uto, K; Sagata, N
      Involvement of Chk1 kinase in prophase I arrest of Xenopus oocytes

      DEVELOPMENTAL BIOLOGY
    53. Suganuma, M; Kawabe, T; Hori, H; Funabiki, T; Okamoto, T
      Sensitization of cancer cells to DNA damage-induced cell death by specificcell cycle G(2) checkpoint abrogation

      CANCER RESEARCH
    54. Lee, SI; Brown, MK; Eastman, A
      Comparison of the efficacy of 7-hydroxystaurosporine (UCN-01) and other staurosporine analogs to abrogate cisplatin-induced cell cycle arrest in human breast cancer cell lines

      BIOCHEMICAL PHARMACOLOGY
    55. RUSSELL P
      CHECKPOINTS ON THE ROAD TO MITOSIS

      Trends in biochemical sciences
    56. Martinho, RG; Lindsay, HD; Flaggs, G; DeMaggio, AJ; Hoekstra, MF; Carr, AM; Bentley, NJ
      Analysis of Rad3 and Chk1 protein kinases defines different checkpoint responses

      EMBO JOURNAL
    57. KUMAGAI A; GUO ZJ; EMAMI KH; WANG SX; DUNPHY WG
      THE XENOPUS CHK1 PROTEIN-KINASE MEDIATES A CAFFEINE-SENSITIVE PATHWAYOF CHECKPOINT CONTROL IN CELL-FREE-EXTRACTS

      The Journal of cell biology
    58. FRANCESCONI S; GRENON M; BOUVIER D; BALDACCI G
      P56(CHK1) PROTEIN-KINASE IS REQUIRED FOR THE DNA-REPLICATION CHECKPOINT AT 37-DEGREES-C IN FISSION YEAST

      EMBO journal
    59. OCONNELL MJ; RALEIGH JM; VERKADE HM; NURSE P
      CHK1 IS A WEE1 KINASE IN THE G(2) DNA-DAMAGE CHECKPOINT INHIBITING CDC2 BY Y15 PHOSPHORYLATION

      EMBO journal


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Documento generato il 29/10/20 alle ore 13:14:17