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    1. Croyle, MA; Cheng, X; Sandhu, A; Wilson, JM
      Development of novel formulations that enhance adenoviral-mediated gene expression in the lung in vitro and in vivo

      MOLECULAR THERAPY
    2. Harvey, BG; Hackett, NR; Ely, S; Crystal, RG
      Host responses and persistence of vector genome following intrabronchial administration of an E1(-)E3(-) adenovirus gene transfer vector to normal individuals

      MOLECULAR THERAPY
    3. Bigger, B; Coutelle, C
      Perspectives on gene therapy for cystic fibrosis airway disease

      BIODRUGS
    4. Chu, Q; St George, JA; Lukason, M; Cheng, SH; Scheule, RK; Eastman, SJ
      EGTA enhancement of adenovirus-mediated gene transfer to mouse tracheal epithelium in vivo

      HUMAN GENE THERAPY
    5. Joseph, PM; O'Sullivan, B; Lapey, A; Dorkin, H; Oren, J; Balfour, R; Perricone, MA; Rosenberg, M; Wadsworth, SC; Smith, AE; St George, JA; Meeker, DP
      Aerosol and lobar administration of a recombinant adenovirus to individuals with cystic fibrosis. I. Methods, safety, and clinical implications

      HUMAN GENE THERAPY
    6. Perricone, MA; Morris, JE; Pavelka, K; Plog, MS; O'Sullivan, BP; Joseph, PM; Dorkin, H; Lapey, A; Balfour, R; Meeker, DP; Smith, AE; Wadsworth, SC; St George, JA
      Aerosol and lobar administration of a recombinant adenovirus to individuals with cystic fibrosis. II. Transfection efficiency in airway epithelium

      HUMAN GENE THERAPY
    7. Lerondel, S; Le Pape, A; Sene, C; Faure, L; Bernard, S; Diot, P; Nicolis, E; Mehtali, M; Lusky, M; Cabrini, G; Pavirani, A
      Radioisotopic imaging allows optimization of adenovirus lung deposition for cystic fibrosis gene therapy

      HUMAN GENE THERAPY
    8. Melotti, P; Nicolis, E; Tamanini, A; Rolfini, R; Pavirani, A; Cabrini, G
      Activation of NF-kappa B mediates ICAM-1 induction in respiratory cells exposed to an adenovirus-derived vector

      GENE THERAPY
    9. Eissa, NT; Erzurum, SC
      Flexible bronchoscopy in molecular biology

      CLINICS IN CHEST MEDICINE
    10. Bastian, A; Schafer, H
      Human alpha-defensin 1 (HNP-1) inhibits adenoviral infection in vitro

      REGULATORY PEPTIDES
    11. Yi, SMP; Lee, JH; Graham, S; Zabner, J; Welsh, MJ
      Adenovirus calcium phosphate coprecipitates enhance squamous cell carcinoma gene transfer

      LARYNGOSCOPE
    12. Benihoud, K; Salone, B; Esselin, S; Opolon, P; Poli, V; Di Giovine, M; Perricaudet, M; Saggio, I
      The role of IL-6 in the inflammatory and humoral response to adenoviral vectors

      JOURNAL OF GENE MEDICINE
    13. Driesse, MJ; Esandi, MC; Kros, JM; Avezaat, CJJ; Vecht, CJ; Zurcher, C; van der Velde, I; Valerio, D; Bout, A; Smitt, PAES
      Intra-CSF administered recombinant adenovirus causes an immune response-mediated toxicity

      GENE THERAPY
    14. Hyde, SC; Southern, KW; Gileadi, U; Fitzjohn, EM; Mofford, KA; Waddell, BE; Gooi, HC; Goddard, CA; Hannavy, K; Smyth, SE; Egan, JJ; Sorgi, FL; Huang, L; Cuthbert, AW; Evans, MJ; Colledge, WH; Higgins, CF; Webb, AK; Gill, DR
      Repeat administration of DNA/liposomes to the nasal epithelium of patientswith cystic fibrosis

      GENE THERAPY
    15. Dummer, R; Bergh, J; Karlsson, Y; Horovitz, JA; Mulder, NH; Huinin, DT; Burg, G; Hofbauer, G; Osanto, S
      Biological activity and safety of adenoviral vector-expressed wild-type p53 after intratumoral injection in melanoma and breast cancer patients with p53-overexpressing tumors

      CANCER GENE THERAPY
    16. Sterman, DH; Molnar-Kimber, K; Iyengar, T; Chang, M; Lanuti, M; Amin, KM; Pierce, BK; Kang, E; Treat, J; Recio, A; Litzky, L; Wilson, JM; Kaiser, LR; Albelda, SM
      A pilot study of systemic corticosteroid administration in conjunction with intrapleural adenoviral vector administration in patients with malignant pleural mesothelioma

      CANCER GENE THERAPY
    17. Ideguchi, M; Kajiwara, K; Yoshikawa, K; Uchida, T; Ito, H
      Local adenovirus-mediated CTLA4-immunoglobulin expression suppresses the immune responses to adenovirus vectors in the brain

      NEUROSCIENCE
    18. Zsengeller, Z; Otake, K; Hossain, SA; Berclaz, PY; Trapnell, BC
      Internalization of adenovirus by alveolar macrophages initiates early proinflammatory signaling during acute respiratory tract infection

      JOURNAL OF VIROLOGY
    19. Kremer, EJ; Boutin, S; Chillon, M; Danos, O
      Canine adenovirus vectors: an alternative for adenovirus mediated gene transfer

      JOURNAL OF VIROLOGY
    20. Guillaume, C; Delepine, P; Mercier, B; Gobin, E; Leroy, JP; Morin, V; Ferec, C
      Phosphonocationic lipids in protein delivery to mice lungs

      JOURNAL OF PHARMACEUTICAL SCIENCES
    21. Verdier, F; Descotes, J
      Preclinical safety evaluation of human gene therapy products

      TOXICOLOGICAL SCIENCES
    22. Thorne, PS; McCray, PB; Howe, TS; O'Neill, MA
      Early-onset inflammatory responses in vivo to adenoviral vectors in the presence or absence of lipopolysaccharide-induced inflammation

      AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
    23. Kaner, RJ; Worgall, S; Leopold, PL; Stolze, E; Milano, E; Hidaka, C; Ramalingam, R; Hackett, NR; Singh, R; Bergelson, J; Finberg, R; Falck-Pedersen, E; Crystal, RG
      Modification of the genetic program of human alveolar macrophages by adenovirus vectors in vitro is feasible but inefficient, limited in part by the low level of expression of the coxsackie/adenovirus receptor

      AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
    24. Lee, JH; Zabner, J; Welsh, MJ
      Delivery of an adenovirus vector in a calcium phosphate coprecipitate enhances the therapeutic index of gene transfer to airway epithelia

      HUMAN GENE THERAPY
    25. Harvey, BG; Worgall, S; Ely, S; Leopold, PL; Crystal, RG
      Cellular immune responses of healthy individuals to intradermal administration of an E1(-)E3(-) adenovirus gene transfer vector

      HUMAN GENE THERAPY
    26. Kitson, C; Angel, B; Judd, D; Rothery, S; Severs, NJ; Dewar, A; Huang, L; Wadsworth, SC; Cheng, SH; Geddes, DM; Alton, EWFW
      The extra- and intracellular barriers to lipid and adenovirus-mediated pulmonary gene transfer in native sheep airway epithelium

      GENE THERAPY
    27. Bastian, A; Bewig, B
      Inhibition of adenovirus-mediated gene transfer by bronchoalveolar lavage fluid

      GENE THERAPY
    28. Pavirani, A; Regulier, E; Bellon, G; Mehtali, M
      Gene therapy for cystic fibrosis: present status and perspectives

      M S-MEDECINE SCIENCES
    29. Papp, Z; Babiuk, LA; Baca-Estrada, ME
      The effect of pre-existing adenovirus-specific immunity on immune responses induced by recombinant adenovirus expressing glycoprotein D of bovine herpesvirus type 1

      VACCINE
    30. Freimuth, P; Springer, K; Berard, C; Hainfeld, N; Bewley, M; Flanagan, J
      Coxsackievirus and adenovirus receptor amino-terminal immunoglobulin V-related domain binds adenovirus type 2 and fiber knob from adenovirus type 12

      JOURNAL OF VIROLOGY
    31. Ramalingam, R; Rafii, S; Worgall, S; Hackett, NR; Crystal, RG
      Induction of endogenous genes following infection of human endothelial cells with an E1(-) E4(+) adenovirus gene transfer vector

      JOURNAL OF VIROLOGY
    32. Ramalingam, R; Rafii, S; Worgall, S; Brough, DE; Crystal, RG
      E1(-)E4(+) adenoviral gene transfer vectors function as a "pro-life" signal to promote survival of primary human endothelial cells

      BLOOD
    33. Ennist, DL
      Gene therapy for lung disease

      TRENDS IN PHARMACOLOGICAL SCIENCES
    34. KNOELL DL; YIU IM
      HUMAN GENE-THERAPY FOR HEREDITARY-DISEASES - A REVIEW OF TRIALS

      American journal of health-system pharmacy
    35. KNOELL DL
      CLINICAL ASPECTS OF GENE-THERAPY

      The Annals of pharmacotherapy
    36. STERMAN DH; TREAT J; LITZKY LA; AMIN KM; COONROD L; MOLNARKIMBER K; RECIO A; KNOX L; WILSON JM; ALBELDA SM; KAISER LR
      ADENOVIRUS-MEDIATED HERPES-SIMPLEX VIRUS THYMIDINE KINASE GANCICLOVIRGENE-THERAPY IN PATIENTS WITH LOCALIZED MALIGNANCY - RESULTS OF A PHASE-I CLINICAL-TRIAL IN MALIGNANT MESOTHELIOMA/

      Human gene therapy
    37. OTAKE K; ENNIST DL; HARROD K; TRAPNELL BC
      NONSPECIFIC INFLAMMATION INHIBITS ADENOVIRUS-MEDIATED PULMONARY GENE-TRANSFER AND EXPRESSION INDEPENDENT OF SPECIFIC ACQUIRED IMMUNE-RESPONSES

      Human gene therapy
    38. SCHULER M; ROCHLITZ C; HOROWITZ JA; SCHLEGEL J; PERRUCHOUD AP; KOMMOSS F; BOLLIGER CT; KAUCZOR HU; DALQUEN P; FRITZ MA; SWANSON S; HERRMANN R; HUBER C
      A PHASE-I STUDY OF ADENOVIRUS-MEDIATED WILD-TYPE P53 GENE-TRANSFER INPATIENTS WITH ADVANCED NONSMALL CELL LUNG-CANCER

      Human gene therapy
    39. NICOLIS E; TAMANINI A; MELOTTI P; ROLFINI R; BERTON G; CASSATELLA MA; BOUT A; PAVIRANI A; CABRINI G
      ICAM-1 INDUCTION IN RESPIRATORY CELLS EXPOSED TO A REPLICATION-DEFICIENT RECOMBINANT ADENOVIRUS IN-VITRO AND IN-VIVO

      Gene therapy
    40. Wolff, RK
      Safety of inhaled proteins for therapeutic use

      JOURNAL OF AEROSOL MEDICINE-DEPOSITION CLEARANCE AND EFFECTS IN THE LUNG
    41. MORNEX JF
      WHAT CAN BE EXPECTED FROM GENE-THERAPY IN RESPIRATORY-DISEASE

      La Presse medicale
    42. Graham, SM
      Gene therapy for cystic fibrosis: perspectives for the otolaryngologist

      CLINICAL OTOLARYNGOLOGY
    43. ROBINSON CB
      IS DNA DESTINY - A CURE FOR CYSTIC-FIBROSIS

      Clinics in chest medicine
    44. KRASNYKH V; DMITRIEV I; MIKHEEVA G; MILLER CR; BELOUSOVA N; CURIEL DT
      CHARACTERIZATION OF AN ADENOVIRUS VECTOR CONTAINING HETEROLOGOUS PEPTIDE EPITOPE IN THE HI LOOP OF THE FIBER KNOB

      Journal of virology
    45. FASBENDER A; LEE JH; WALTERS RW; MONINGER TO; ZABNER J; WELSH MJ
      INCORPORATION OF ADENOVIRUS IN CALCIUM-PHOSPHATE PRECIPITATES ENHANCES GENE-TRANSFER TO AIRWAY EPITHELIA IN-VITRO AND IN-VIVO

      The Journal of clinical investigation
    46. DETTMAN RW; DENETCLAW W; ORDAHL CP; BRISTOW J
      COMMON EPICARDIAL ORIGIN OF CORONARY VASCULAR SMOOTH-MUSCLE, PERIVASCULAR FIBROBLASTS, AND INTERMYOCARDIAL FIBROBLASTS IN THE AVIAN HEART

      Developmental biology
    47. Rosenberg, SA; Zhai, YF; Yang, JC; Schwartzentruber, DJ; Hwu, P; Marincola, F; Topalian, SL; Restifo, NP; Seipp, CA; Einhorn, JH; Roberts, B; White, DE
      Immunizing patients with metastatic melanoma using recombinant adenoviruses encoding MART-1 or gp100 melanoma antigens

      JOURNAL OF THE NATIONAL CANCER INSTITUTE
    48. CANNIZZO SJ; FREY BM; RAFFI S; MOORE MAS; EATON D; SUZUKI M; SINGH R; MACK CA; CRYSTAL RG
      AUGMENTATION OF BLOOD-PLATELET LEVELS BY INTRATRACHEAL ADMINISTRATIONOF AN ADENOVIRUS VECTOR ENCODING HUMAN THROMBOPOIETIN CDNA

      Nature biotechnology
    49. THIBAULT V; TERLAIN B; GRAHAM FL; GAULDIE J
      CONSTRUCTION AND CHARACTERIZATION OF A REPLICATION-DEFICIENT ADENOVIRUS EXPRESSING RAT-SOLUBLE INTERLEUKIN-6 RECEPTOR

      Molecular medicine
    50. CRYSTAL RG; HIRSCHOWITZ E; LIEBERMAN M; DALY J; KAZAM E; HENSCHKE C; YANKELEVITZ D; KEMENY N; SILVERSTEIN R; OHWADA A; RUSSI T; MASTRANGELI A; SANDERS A; COOKE J; HARVEY BG
      PHASE-I STUDY OF DIRECT ADMINISTRATION OF A REPLICATION DEFICIENT ADENOVIRUS VECTOR CONTAINING THE ESCHERICHIA-COLI CYTOSINE DEAMINASE GENETO METASTATIC COLON-CARCINOMA OF THE LIVER IN ASSOCIATION WITH THE ORAL-ADMINISTRATION OF THE PRO-DRUG 5-FLUOROCYTOSINE

      Human gene therapy
    51. RUSSI TJ; HIRSCHOWITZ EA; CRYSTAL RG
      DELAYED-TYPE HYPERSENSITIVITY RESPONSE TO HIGH-DOSES OF ADENOVIRAL VECTORS

      Human gene therapy
    52. WORGALL S; WOLFF G; FALCKPEDERSEN E; CRYSTAL RG
      INNATE IMMUNE-MECHANISMS DOMINATE ELIMINATION OF ADENOVIRAL VECTORS FOLLOWING IN-VIVO ADMINISTRATION

      Human gene therapy
    53. MACK CA; SONG WR; CARPENTER H; WICKHAM TJ; KOVESDI I; HARVEY BG; MAGOVERN CJ; ISOM OW; ROSENGART T; FALCKPEDERSEN E; HACKETT NR; CRYSTAL RG; MASTRANGELI A
      CIRCUMVENTION OF ANTI-ADENOVIRUS NEUTRALIZING IMMUNITY BY ADMINISTRATION OF AN ADENOVIRAL VECTOR OF AN ALTERNATE SEROTYPE

      Human gene therapy
    54. SAGGIO I; CIAPPONI L; SAVINO R; CILIBERTO G; PERRICAUDET M
      ADENOVIRUS-MEDIATED GENE-TRANSFER OF A HUMAN IL-6 ANTAGONIST

      Gene therapy
    55. SCARIA A; STGEORGE JA; GREGORY RJ; NOELLE RJ; WADSWORTH SC; SMITH AE; KAPLAN JM
      ANTIBODY TO CD40 LIGAND INHIBITS BOTH HUMORAL AND CELLULAR IMMUNE-RESPONSES TO ADENOVIRAL VECTORS AND FACILITATES REPEATED ADMINISTRATION TO MOUSE AIRWAY

      Gene therapy
    56. ISLAM KB; BLOMBERG P; WIKSTROM K; SMITH CIE
      AN ACADEMIC CENTER FOR GENE-THERAPY RESEARCH WITH CLINICAL GRADE MANUFACTURING CAPABILITY

      Annals of medicine
    57. LASHFORD LS
      POSSIBILITIES OF GENE THERAPIES FOR CANCER

      Annals of medicine
    58. ROCHAT T
      CYSTIC-FIBROSIS GENE-THERAPY WITH RECOMBI NANT ADENOVIRUS - A LONG WAY TO GO

      Schweizerische medizinische Wochenschrift
    59. DAVIS PB; BYARD PJ; KONSTAN MW
      IDENTIFYING TREATMENTS THAT HALT PROGRESSION OF PULMONARY-DISEASE IN CYSTIC-FIBROSIS

      Pediatric research
    60. SYLVESTER KG; YANG EY; CASS DL; CROMBLEHOLME TM; ADZICK NS
      FETOSCOPIC GENE-THERAPY FOR CONGENITAL LUNG-DISEASE

      Journal of pediatric surgery
    61. BENNETT MJ; ABERLE AM; BALASUBRAMANIAM RP; MALONE JG; MALONE RW; NANTZ MH
      CATIONIC LIPID-MEDIATED GENE DELIVERY TO MURINE LUNG - CORRELATION OFLIPID HYDRATION WITH IN-VIVO TRANSFECTION ACTIVITY

      Journal of medicinal chemistry
    62. ZABNER J; CHENG SH; MEEKER D; LAUNSPACH J; BALFOUR R; PERRICONE MA; MORRIS JE; MARSHALL J; FASBENDER A; SMITH AE; WELSH MJ
      COMPARISON OF DNA-LIPID COMPLEXES AND DNA ALONE FOR GENE-TRANSFER TO CYSTIC-FIBROSIS AIRWAY EPITHELIA IN-VIVO

      The Journal of clinical investigation
    63. ZABNER J; FREIMUTH P; PUGA A; FABREGA A; WELSH MJ
      LACK OF HIGH-AFFINITY FIBER RECEPTOR ACTIVITY EXPLAINS THE RESISTANCEOF CILIATED AIRWAY EPITHELIA TO ADENOVIRUS INFECTION

      The Journal of clinical investigation
    64. TSUKUI T; KANEGAE Y; SAITO I; TOYODA Y
      TRANSGENESIS BY ADENOVIRUS-MEDIATED GENE-TRANSFER INTO MOUSE ZONA-FREE EGGS

      Nature biotechnology
    65. KAGAMI H; OCONNELL BC; BAUM BJ
      EVIDENCE FOR THE SYSTEMIC DELIVERY OF A TRANSGENE PRODUCT FROM SALIVARY-GLANDS

      Human gene therapy
    66. GOLDMAN M; SU Q; WILSON JM
      GRADIENT OF RGD-DEPENDENT ENTRY OF ADENOVIRAL VECTOR IN NASAL AND INTRAPULMONARY EPITHELIA - IMPLICATIONS FOR GENE-THERAPY OF CYSTIC-FIBROSIS

      Gene therapy
    67. COUTELLE C
      GENE-THERAPY RESEARCH FOR CYSTIC-FIBROSIS

      Journal of clinical biochemistry and nutrition
    68. MITTEREDER N; MARCH KL; TRAPNELL BC
      EVALUATION OF THE CONCENTRATION AND BIOACTIVITY OF ADENOVIRUS VECTORSFOR GENE-THERAPY

      Journal of virology
    69. ZABNER J; ZEIHER BG; FRIEDMAN E; WELSH MJ
      ADENOVIRUS-MEDIATED GENE-TRANSFER TO CILIATED AIRWAY EPITHELIA REQUIRES PROLONGED INCUBATION-TIME

      Journal of virology
    70. RANGARAJAN PN; PADMANABAN G
      GENE-THERAPY - PRINCIPLES, PRACTICE, PROBLEMS AND PROSPECTS

      Current Science


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Documento generato il 10/08/20 alle ore 13:55:36