Catalogo Articoli (Spogli Riviste)

HELP
ATTENZIONE: attualmente gli articoli Current Contents (fonte ISI) a partire dall'anno 2002 sono consultabili sulla Risorsa On-Line

Le informazioni sugli articoli di fonte ISI sono coperte da copyright

La ricerca find articoli where soggetti phrase all words 'CELL-SPECIFIC EXPRESSION' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 308 riferimenti
Si mostrano 100 riferimenti a partire da 1
Selezionare un intervallo

Per ulteriori informazioni selezionare i riferimenti di interesse.

    1. Yang, YS; Yang, MCW; Wang, B; Weissler, JC
      BR22, a novel protein, interacts with thyroid transcription factor-1 and activates the human surfactant protein B promoter

      AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
    2. Hong, ST; Lee, MY; Kim, SR
      Molecular cloning of the anther-preferential nonspecific lipid transfer protein cDNA in hot pepper by mRNA differential display

      MOLECULES AND CELLS
    3. Brink, C; Chowdhury, K; Gruss, P
      Pax4 regulatory elements mediate beta cell specific expression in the pancreas

      MECHANISMS OF DEVELOPMENT
    4. Pincas, H; Amoyel, K; Counis, R; Laverriere, JN
      Proximal cis-acting elements, including steroidogenic factor 1, mediate the efficiency of a distal enhancer in the promoter of the rat gonadotropin-releasing hormone receptor gene

      MOLECULAR ENDOCRINOLOGY
    5. Mezquita, B; Mezquita, J; Durfort, M; Mezquita, C
      Constitutive and heat-shock induced expression of Hsp70 mRNA during chicken testicular development and regression

      JOURNAL OF CELLULAR BIOCHEMISTRY
    6. Scudiero, R; Carginale, V; Capasso, C; Riggio, M; Filosa, S; Parisi, E
      Structural and functional analysis of metal regulatory elements in the promoter region of genes encoding metallothionein isoforms in the Antarctic fish Chionodraco hamatus (icefish)

      GENE
    7. Bommert, P; Werr, W
      Gene expression patterns in the maize caryopsis: clues to decisions in embryo and endosperm development

      GENE
    8. Ding, YM; Sigmund, CD
      Androgen-dependent regulation of human angiotensinogen expression in KAP-hAGT transgenic mice

      AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
    9. Hardy, DO; Niu, EM; Catterall, JF
      Kap promoter analysis in vivo: a regulatory role for a truncated L1 repeat

      MOLECULAR AND CELLULAR ENDOCRINOLOGY
    10. Shneider, BL
      Intestinal bile acid transport: Biology, physiology, and pathophysiology

      JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
    11. Monnet, FP; Dieryck, W; Boutrot, F; Joudrier, P; Gautier, MF
      Purification, characterisation and cDNA cloning of a type 2 (7 kDa) lipid transfer protein from Triticum durum

      PLANT SCIENCE
    12. Andersen, B; Rosenfeld, MG
      POU domain factors in the neuroendocrine system: Lessons from developmental biology provide insights into human disease

      ENDOCRINE REVIEWS
    13. Dasen, JS; Rosenfeld, MG
      Signaling and transcriptional mechanisms in pituitary development

      ANNUAL REVIEW OF NEUROSCIENCE
    14. Ghoshal, K; Jacob, ST
      Regulation of metallothionein gene expression

      PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 66
    15. Dunn, MA; O'Brien, G; Brown, APC; Vural, S; Hughes, MA
      Resistance to abiotic freezing stress in cereals

      ADVANCES IN BOTANICAL RESEARCH INCORPORATING ADVANCES IN PLANT PATHOLOGY, VOL 34
    16. Ortega, JL; Temple, SJ; Sengupta-Gopalan, C
      Constitutive overexpression of cytosolic glutamine synthetase (GS(1)) genein transgenic alfalfa demonstrates that GS(1) may be regulated at the level of RNA stability and protein turnover

      PLANT PHYSIOLOGY
    17. Sakurai, N; Katayama, Y; Yamaya, T
      Overlapping expression of cytosolic glutamine synthetase and phenylalanineammonia-lyase in immature leaf blades of rice

      PHYSIOLOGIA PLANTARUM
    18. Kim, HS; Hong, SJ; LeDoux, MS; Kim, KS
      Regulation of the tyrosine hydroxylase and dopamine beta-hydroxylase genesby the transcription factor AP-2

      JOURNAL OF NEUROCHEMISTRY
    19. Tester, M; Leigh, RA
      Partitioning of nutrient transport processes in roots

      JOURNAL OF EXPERIMENTAL BOTANY
    20. Pan, L; Black, TA; Shi, Q; Jones, CA; Petrovic, N; Loudon, J; Kane, C; Sigmund, CD; Gross, KW
      Critical roles of a cyclic AMP responsive element and an E-box in regulation of mouse renin gene expression

      JOURNAL OF BIOLOGICAL CHEMISTRY
    21. Chen, F; Ma, L; Al-Ansari, N; Shneider, B
      The role of AP-1 in the transcriptional regulation of the rat apical sodium-dependent bile acid transporter

      JOURNAL OF BIOLOGICAL CHEMISTRY
    22. Collingwood, TN; Urnov, FD; Chatterjee, VKK; Wolffe, AP
      Chromatin remodeling by the thyroid hormone receptor in regulation of the thyroid-stimulating hormone alpha-subunit promoter

      JOURNAL OF BIOLOGICAL CHEMISTRY
    23. Lovshin, J; Estall, J; Yusta, B; Brown, TJ; Drucker, DJ
      Glucagon-like peptide (GLP)-2 action in the murine central nervous system is enhanced by elimination of GLP-1 receptor signaling

      JOURNAL OF BIOLOGICAL CHEMISTRY
    24. Gainer, H; Fields, RL; House, SB
      Vasopressin gene expression: Experimental models and strategies

      EXPERIMENTAL NEUROLOGY
    25. Udono, T; Takahashi, K; Yasumoto, K; Yoshizawa, M; Takeda, K; Abe, T; Tamai, M; Shibahara, S
      Expression of tyrosinase-related protein 2/DOPAchrome tautomerase in the retinoblastoma

      EXPERIMENTAL EYE RESEARCH
    26. Richards, JS
      Perspective: The ovarian follicle - A perspective in 2001

      ENDOCRINOLOGY
    27. Cheng, KWA; Chow, BKC; Leung, PCK
      Functional mapping of a placenta-specific upstream promoter for human gonadotropin-releasing hormone receptor gene

      ENDOCRINOLOGY
    28. Wolf, HM; Thon, V; Gulle, H; Lechleitner, S; Eibl, MM; Petzelbauer, P
      Residual expression of functional MHC class II molecules in twin brothers with MHC class II deficiency is cell type specific

      BRITISH JOURNAL OF HAEMATOLOGY
    29. Velazhahan, R; Radhajeyalakshmi, R; Thangavelu, R; Muthukrishnan, S
      An antifungal protein purified from pearl millet seeds shows sequence homology to lipid transfer proteins

      BIOLOGIA PLANTARUM
    30. Lam, PYP; Breakefield, XO
      Hybrid vector designs to control the delivery, fate and expression of transgenes

      JOURNAL OF GENE MEDICINE
    31. Winter, H; Huber, SC
      Regulation of sucrose metabolism in higher plants: Localization and regulation of activity of key enzymes

      CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
    32. Margana, R; Berhane, K; Alam, MN; Boggaram, V
      Identification of functional TTF-1 and Sp1/Sp3 sites in the upstream promoter region of rabbit SP-B gene

      AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
    33. Pavlova, ZB; Lutova, LA
      Nodulation as a model for studying differentiation in higher plants

      RUSSIAN JOURNAL OF GENETICS
    34. Sahgal, N; Knipp, GT; Liu, B; Chapman, BM; Dai, G; Soares, MJ
      Identification of two new nonclassical members of the rat prolactin family

      JOURNAL OF MOLECULAR ENDOCRINOLOGY
    35. Bouvard, V; Zaitchouk, T; Vacher, M; Duthu, A; Canivet, M; Choisy-Rossi, C; Nieruchalski, M; May, E
      Tissue and cell-specific expression of the p53-target genes: bax, fas, mdm2 and waf1/p21, before and following ionising irradiation in mice

      ONCOGENE
    36. Bilbao, R; Gerolami, R; Bralet, MP; Qian, C; Tran, PL; Tennant, B; Prieto, J; Brechot, C
      Transduction efficacy, antitumoral effect, and toxicity of adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir therapy of hepatocellular carcinoma: The woodchuck animal model

      CANCER GENE THERAPY
    37. Kavroulakis, N; Flemetakis, E; Aivalakis, G; Katinakis, P
      Carbon metabolism in developing soybean root nodules: The role of carbonicanhydrase

      MOLECULAR PLANT-MICROBE INTERACTIONS
    38. Jimenez-Zurdo, JI; Frugier, F; Crespi, MD; Kondorosi, A
      Expression profiles of 22 novel molecular markers for organogenetic pathways acting in alfalfa nodule development

      MOLECULAR PLANT-MICROBE INTERACTIONS
    39. Takeuchi, S; Takeuchi, T; Yamamoto, H
      A possible mechanism for feedback regulation of the mouse tyrosinase gene by its 3 ' non-coding RNA fragments

      PIGMENT CELL RESEARCH
    40. Goding, CR
      Mitf from neural crest to melanoma: signal transduction and transcription in the melanocyte lineage

      GENES & DEVELOPMENT
    41. Crosby, JA; Konopka, JB; Fields, S
      Constitutive activation of the Saccharomyces cerevisiae transcriptional regulator Ste12p by mutations at the amino-terminus

      YEAST
    42. Anwer, K; Bailey, A; Sullivan, SM
      Targeted gene delivery: A two-pronged approach

      CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS
    43. Winter, H; Huber, SC
      Regulation of sucrose metabolism in higher plants: Localization and regulation of activity of key enzymes

      CRITICAL REVIEWS IN PLANT SCIENCES
    44. Douliez, JP; Michon, T; Elmorjani, K; Marion, D
      Structure, biological and technological functions of lipid transfer proteins and indolines, the major lipid binding proteins from cereal kernels

      JOURNAL OF CEREAL SCIENCE
    45. Cioci, LK; Qiu, L; Freedman, JH
      Transgenic strains of the nematode Caenorhabditis elegans as biomonitors of metal contamination

      ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
    46. Stoddart, JH; Ladd, D; Bronson, RT; Harmon, M; Jaworski, J; Pritzker, C; Lausen, N; Smith, BD
      Transgenic mice with a mutated collagen promoter display normal response during bleomycin-induced fibrosis and possess neurological abnormalities

      JOURNAL OF CELLULAR BIOCHEMISTRY
    47. Gronostajski, RM
      Roles of the NFI/CTF gene family in transcription and development

      GENE
    48. Rollini, P; Fournier, REK
      Differential regulation of gene activity and chromatin structure within the human serpin gene cluster at 14q32.1 in macrophage microcell hybrids

      NUCLEIC ACIDS RESEARCH
    49. Harrington, KJ; Linardakis, E; Vile, RG
      Transcriptional control: An essential component of cancer gene therapy strategies?

      ADVANCED DRUG DELIVERY REVIEWS
    50. Nettelbeck, DM; Jerome, V; Muller, R
      Gene therapy - designer promoters for tumour targeting

      TRENDS IN GENETICS
    51. Carvalho, H; Lima, L; Lescure, N; Camut, S; Salema, R; Cullimore, J
      Differential expression of the two cytosolic glutamine synthetase genes invarious organs of Medicago truncatula

      PLANT SCIENCE
    52. Arondel, V; Vergnolle, C; Cantrel, C; Kader, JC
      Lipid transfer proteins are encoded by a small multigene family in Arabidopsis thaliana

      PLANT SCIENCE
    53. Qian, C; Drozdzik, M; Caselmann, WH; Prieto, J
      The potential of gene therapy in the treatment of hepatocellular carcinoma

      JOURNAL OF HEPATOLOGY
    54. Amae, S; Yasumoto, K; Takeda, K; Udono, T; Takahashi, K; Shibahara, S
      Identification of a composite enhancer of the human tyrosinase-related protein 2/DOPAchrome tautomerase gene

      BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION
    55. Udono, T; Yasumoto, K; Takeda, K; Amae, S; Watanabe, K; Saito, H; Fuse, N; Tachibana, M; Takahashi, K; Tamai, M; Shibahara, S
      Structural organization of the human microphthalmia-associated transcription factor gene containing four alternative promoters

      BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION
    56. Gualtieri, G; Bisseling, T
      The evolution of nodulation

      PLANT MOLECULAR BIOLOGY
    57. Sinn, PL; Sigmund, CD
      Transgenic models as tools for studying the regulation of human renin expression

      REGULATORY PEPTIDES
    58. Gannon, M; Gilday, D; Rifkind, AB
      TCDD induces CYP1A4 and CYP1A5 in chick liver and kidney and only CYP1A4, an enzyme lacking arachidonic acid epoxygenase activity, in myocardium and vascular endothelium

      TOXICOLOGY AND APPLIED PHARMACOLOGY
    59. Okubara, PA; Fujishige, NA; Hirsch, AM; Berry, AM
      Dg93, a nodule-abundant mRNA of Datisca glomerata with homology to a soybean early nodulin gene

      PLANT PHYSIOLOGY
    60. Toyofuku, K; Kasahara, M; Yamaguchi, J
      Characterization and expression of monosaccharide transporters (OsMSTs) inrice

      PLANT AND CELL PHYSIOLOGY
    61. Regente, MC; de la Canal, L
      Purification, characterization and antifungal properties of a lipid-transfer protein from sunflower (Helianthus annuus) seeds

      PHYSIOLOGIA PLANTARUM
    62. Van de Weerdt, C; Peers, B; Belayew, A; Martial, JA; Muller, M
      Far upstream sequences regulate the human prolactin promoter transcription

      NEUROENDOCRINOLOGY
    63. Ivanov, IP; Rohrwasser, A; Terreros, DA; Gesteland, RF; Atkins, JF
      Discovery of a spermatogenesis stage-specific ornithine decarboxylase antizyme: Antizyme 3

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    64. McLean, PJ; Shpektor, D; Bandyopadhyay, S; Russek, SJ; Farb, DH
      A minimal promoter for the GABA(A) receptor alpha 6-subunit gene controls tissue specificity

      JOURNAL OF NEUROCHEMISTRY
    65. Golob, M; Buettner, R; Bosserhoff, AK
      Characterization of a transcription factor binding site, specifically activating MIA transcription in melanoma

      JOURNAL OF INVESTIGATIVE DERMATOLOGY
    66. Hedley, PE; Maddison, AL; Davidson, D; Machray, GC
      Differential expression of invertase genes in internal and external phloemtissues of potato (Solanum tuberosum L.)

      JOURNAL OF EXPERIMENTAL BOTANY
    67. Strayer, DS; Korutla, L
      Activation of surfactant protein-B transcription: Signaling through the SP-A receptor utilizing the PI3 kinase pathway

      JOURNAL OF CELLULAR PHYSIOLOGY
    68. Ritz-Laser, B; Estreicher, A; Gauthier, B; Philippe, J
      The paired homeodomain transcription factor Pax-2 is expressed in the endocrine pancreas and transactivates the glucagon gene promoter

      JOURNAL OF BIOLOGICAL CHEMISTRY
    69. He, YC; Crouch, EC; Rust, K; Spaite, E; Brody, SL
      Proximal promoter of the surfactant protein D gene - Regulatory roles of AP-1, forkhead box, and GT box binding proteins

      JOURNAL OF BIOLOGICAL CHEMISTRY
    70. Grzeskowiak, R; Amin, J; Oetjen, E; Knepel, W
      Insulin responsiveness of the glucagon gene conferred by interactions between proximal promoter and more distal enhancer-like elements involving the paired-domain transcription factor Pax6

      JOURNAL OF BIOLOGICAL CHEMISTRY
    71. Laumen, H; Nielsen, PJ; Wirth, T
      The BOB.1/OBF.1 co-activator is essential for octamer-dependent transcription in B cells

      EUROPEAN JOURNAL OF IMMUNOLOGY
    72. Duval, DL; Farris, AR; Quirk, CC; Nett, TM; Hamernik, DL; Clay, CM
      Responsiveness of the ovine gonadotropin-releasing hormone receptor gene to estradiol and gonadotropin-releasing hormone is not detectable in vitro but is revealed in transgenic mice

      ENDOCRINOLOGY
    73. Ruiz, J; Qian, C; Drozdzik, M; Prieto, J
      Gene therapy of viral hepatitis and hepatocellular carcinoma

      JOURNAL OF VIRAL HEPATITIS
    74. Maxwell, IH; Cripe, TP
      Transcriptional targeting

      TUMOR TARGETING
    75. Shibahara, S; Yasumoto, K; Amae, S; Fuse, N; Udono, T; Takahashi, K
      Implications of isoform multiplicity of microphthalmia-associated transcription factor in the pathogenesis of auditory-pigmentary syndromes

      JOURNAL OF INVESTIGATIVE DERMATOLOGY SYMPOSIUM PROCEEDINGS
    76. Norwitz, ER; Jeong, KH; Chin, WW
      Molecular mechanisms of gonadotropin-releasing hormone receptor gene regulation

      JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION
    77. Charon, C; Sousa, C; Crespi, M; Kondorosi, A
      Alteration of enod40 expression modifies Medicago truncatula root nodule development induced by Sinorhizobium meliloti

      PLANT CELL
    78. Alcorn, JL; Hammer, RE; Graves, KR; Smith, ME; Maika, SD; Michael, LF; Gao, EW; Wang, Y; Mendelson, CR
      Analysis of genomic regions involved in regulation of the rabbit surfactant protein A gene in transgenic mice

      AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
    79. Lee, CK; Kang, HS; Lee, BJ; Kang, HM; Choi, WS; Kang, SG
      Effects of dopamine and melatonin on the regulation of the PIT-1 isotype, placental growth hormone and lactogen gene expressions in the rat placenta

      MOLECULES AND CELLS
    80. Dasen, JS; Rosenfeld, MG
      Combinatorial codes in signaling and synergy: lessons from pituitary development

      CURRENT OPINION IN GENETICS & DEVELOPMENT
    81. Young, WS; Iacangelo, A; Luo, XZJ; King, C; Duncan, K; Ginns, EI
      Transgenic expression of green fluorescent protein in mouse oxytocin neurones

      JOURNAL OF NEUROENDOCRINOLOGY
    82. Pieri, I; Klein, M; Bayertz, C; Gerspach, J; van der Ploeg, A; Pfizenmaier, K; Eisel, U
      Regulation of the murine NMDA-receptor-subunit NR2C promoter by Sp1 and fushi tarazu factor1 (FTZ-F1) homologues

      EUROPEAN JOURNAL OF NEUROSCIENCE
    83. Moto, K; Salam, SEA; Sakurai, S; Iwami, M
      Gene transfer into insect brain and cell-specific expression of bombyxin gene

      DEVELOPMENT GENES AND EVOLUTION
    84. Jakobsson, S; Borg, B; Haux, C; Hyllner, SJ
      An 11-ketotestosterone induced kidney-secreted protein: the nest building glue from male three-spined stickleback, Gasterosteus aculeatus

      FISH PHYSIOLOGY AND BIOCHEMISTRY
    85. Hill, ME; Asa, SL; Drucker, DJ
      Essential requirement for Pax6 in control of enteroendocrine proglucagon gene transcription

      MOLECULAR ENDOCRINOLOGY
    86. White, BR; Duval, DL; Mulvaney, JM; Roberson, MS; Clay, CM
      Homologous regulation of the gonadotropin-releasing hormone receptor gene is partially mediated by protein kinase C activation of an activator protein-1 element

      MOLECULAR ENDOCRINOLOGY
    87. Tanaka, K; Fisher, SE; Craig, IW
      Characterization of novel promoter and enhancer elements of the mouse homologue of the Dent disease gene, Clcn5, implicated in X-linked hereditary nephrolithiasis

      GENOMICS
    88. D'Aoust, MA; Nguyen-Quoc, B; Le, VQ; Yelle, S
      Upstream regulatory regions from the maize Sh1 promoter confer tissue specific expression of the beta-glucuronidase gene in tomato

      PLANT CELL REPORTS
    89. Igarashi, P; Shashikant, CS; Thomson, RB; Whyte, DA; Liu-Chen, SX; Ruddle, FH; Aronson, PS
      Ksp-cadherin gene promoter. II. Kidney-specific activity in transgenic mice

      AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
    90. Ishii, T; Ohsugi, K; Nakamura, S; Sato, K; Hashimoto, M; Mikoshiba, K; Sakuragawa, N
      Gene expression of oligodendrocyte markers in human amniotic epithelial cells using neural cell-type-specific expression system

      NEUROSCIENCE LETTERS
    91. Christoffels, VM; Sassi, H; Ruijter, JM; Moorman, AFM; Grange, T; Lamers, WH
      A mechanistic model for the development and maintenance of portocentral gradients in gene expression in the liver

      HEPATOLOGY
    92. Bratke, J; Kietzmann, T; Jungermann, K
      Identification of an oxygen-responsive element in the 5 '-flanking sequence of the rat cytosolic phosphoenolpyruvate carboxykinase-1 gene, modulatingits glucagon-dependent activation

      BIOCHEMICAL JOURNAL
    93. Wang, QJ; Raghow, R
      Molecular mechanisms of regulation of type I collagen biosynthesis

      PROCEEDINGS OF THE INDIAN ACADEMY OF SCIENCES-CHEMICAL SCIENCES
    94. Choi, YA; Kim, SG; Kwon, YM
      The plastidic glutamine synthetase activity is directly modulated by meansof redox change at two unique cysteine residues

      PLANT SCIENCE
    95. Palu, G; Bonaguro, R; Marcello, A
      In pursuit of new developments for gene therapy of human diseases

      JOURNAL OF BIOTECHNOLOGY
    96. Tan, J; Patel, MS
      Cloning and characterization of a 5.9 kb promoter region of the human pyruvate dehydrogenase alpha subunit gene

      BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY
    97. Sohal, AK; Pallas, JA; Jenkins, GI
      The promoter of a Brassica napus lipid transfer protein gene is active in a range of tissues and stimulated by light and viral infection in transgenic Arabidopsis

      PLANT MOLECULAR BIOLOGY
    98. Canton, FR; Suarez, MF; Jose-Estanyol, M; Canovas, FM
      Expression analysis of a cytosolic glutamine synthetase gene in cotyledonsof Scots pine seedlings: developmental, light regulation and spatial distribution of specific transcripts

      PLANT MOLECULAR BIOLOGY
    99. Vauterin, M; Frankard, V; Jacobs, M
      The Arabidopsis thaliana dhdps gene encoding dihydrodipicolinate synthase,key enzyme of lysine biosynthesis, is expressed in a cell-specific manner

      PLANT MOLECULAR BIOLOGY
    100. Kleines, M; Elster, RC; Rodrigo, MJ; Blervacq, AS; Salamini, F; Bartels, D
      Isolation and expression analysis of two stress-responsive sucrose-synthase genes from the resurrection plant Craterostigma plantagineum (Hochst.)

      PLANTA


ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/01/21 alle ore 00:34:34