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Experimental culture conditions are critical for ex vivo expansion of hematopoietic cells
JOURNAL OF HEMATOTHERAPY & STEM CELL RESEARCH
Recent developments in the regulation of peripheral blood stem cell mobilization and engraftment by cytokines, chemokines, and adhesion molecules
JOURNAL OF HEMATOTHERAPY & STEM CELL RESEARCH
Mobilization of dendritic cells and NK cells in non-Hodgkin's lymphoma patients mobilized with different growth factors
JOURNAL OF HEMATOTHERAPY & STEM CELL RESEARCH
Influence of medium components on ex vivo megakaryocyte expansion
JOURNAL OF HEMATOTHERAPY & STEM CELL RESEARCH
A capsid-modified adenovirus vector devoid of all viral genes: Assessment of transduction and toxicity in human hematopoietic cells
MOLECULAR THERAPY
Gene transfer into baboon repopulating cells: A comparison of Flt-3 ligandand megakaryocyte growth and development factor versus IL-3 during ex vivotransduction
MOLECULAR THERAPY
Enhanced transgene expression in cord blood CD34(+)-derived hematopoietic cells, including developing T cells and NOD/SCID mouse repopulating cells, following transduction with modified TRIP lentiviral vectors
MOLECULAR THERAPY
Functional correction of Fanconi anemia group C hematopoietic cells by theuse of a novel lentiviral vector
MOLECULAR THERAPY
In vitro generation of Epstein-Barr virus-specific cytotoxic T cells in patients receiving haplo-identical allogeneic stem cell transplantation
JOURNAL OF IMMUNOTHERAPY
Replicative response, immunophenotype, and functional activity of monocyte-derived versus CD34(+)-derived dendritic cells following exposure to various expansion and maturational stimuli
CLINICAL IMMUNOLOGY
The effect of G-CSF on lymphocyte subsets and CD34+cells in allogeneic stem cell transplantation
TRANSFUSION AND APHERESIS SCIENCE
Expansion of megakaryocyte progenitors from cryopreserved leukocyte concentrates of human placental and umbilical cord blood in short-term liquid culture
CYTOTHERAPY
Use of the hematopoietic progenitor cell parameter on the Sysmex SE-9500 (TM) as a screening tool for circulating hematopoietic precursors in pediatrics
INFUSION THERAPY AND TRANSFUSION MEDICINE-INFUSIONSTHERAPIE UND TRANSFUSIONSMEDIZIN
Fibrinogen cooperates with cytokines to induce interleukin-6 receptor mRNAexpression in human hematopoietic CD34(+) progenitors
EUROPEAN CYTOKINE NETWORK
Transduction of CD34+cells with lentiviral vectors enables the production of large quantities of transgene-expressing immature and mature dendritic cells
JOURNAL OF GENE MEDICINE
Gene therapy of severe combined immunodeficiencies
JOURNAL OF GENE MEDICINE
Optimisation of retroviral supernatant production conditions for the genetic modification of human CD34(+) cells
JOURNAL OF GENE MEDICINE
Purified canine CD34(+)Lin(-) marrow cells transduced with retroviral vectors give rise to long-term multi-lineage hematopoiesis
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
A novel protocol that allows short-term stem cell expansion of both committed and pluripotent hematopoietic progenitor cells suitable for clinical use
BLOOD CELLS MOLECULES AND DISEASES
Proliferation of human hematopoietic bone marrow cells in simulated microgravity
IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
Cell cycle activation of peripheral blood stem and progenitor cells expanded ex vivo with SCF, FLT-3 ligand, TPO, and IL-3 results in accelerated granulocyte recovery in a baboon model of autologous transplantation but G(0)/G(1) and S/G(2)/M graft cell content does not correlate with tranplantability
STEM CELLS
The SDF-1-CXCR4 axis stimulates VEGF secretion and activates integrins butdoes not affect proliferation and survival in lymphohematopoietic cells
STEM CELLS
Hybrid HIV/MSCV LTR enhances transgene expression of lentiviral vectors inhuman CD34(+) hematopoietic cells
STEM CELLS
High levels of transgene expression following transduction of long-term NOD/SCID-repopulating human cells with a modified lentiviral vector
STEM CELLS
Autocrine/paracrine mechanisms in human hematopoiesis
STEM CELLS
Transplantation hematopoiesis
CURRENT OPINION IN HEMATOLOGY
Progress in clinical application of use of progenitor cells expanded with hematopoietic growth factors
CURRENT OPINION IN HEMATOLOGY
Cytokine-augmented culture of haematopoietic progenitor cells in a novel three-dimensional cell growth matrix
CYTOKINE
Approaches to gene therapy for human immunodeficiency virus infection
HUMAN GENE THERAPY
Lack of superinfection interference in retroviral vector producer cells
HUMAN GENE THERAPY
Stable transduction with lentiviral vectors and amplification of immature hematopoietic progenitors from cord blood of preterm human fetuses
HUMAN GENE THERAPY
Highly efficient targeted transduction of undifferentiated human hematopoietic cells by adenoviral vectors displaying fiber knobs of subgroup B
HUMAN GENE THERAPY
Simplified retroviral vector GCsap with murine stem cell virus long terminal repeat allows high and continued expression of enhanced green fluorescent protein by human hematopoietic progenitors engrafted in nonobese diabetic/severe combined immunodeficient mice
HUMAN GENE THERAPY
Ultrastructural features of CD34+ hematopoietic progenitor cells from bonemarrow, peripheral blood and umbilical cord blood
LEUKEMIA & LYMPHOMA
High-efficiency retroviral transduction of fetal liver CD38-CD34++ cells: Implications for in utero and ex utero gene therapy
FETAL DIAGNOSIS AND THERAPY
Expansion of CD34(+) cells from human umbilical cord blood by FL and/or TPO gene transfected human marrow stromal cell lines
SCIENCE IN CHINA SERIES C-LIFE SCIENCES
Genetically modified immunocompetent cells in HIV infection
GENE THERAPY
Efficient infection of primitive hematopoietic stem cells by modified adenovirus
GENE THERAPY
Lentiviral-mediated gene transfer into haematopoietic stem cells
JOURNAL OF INTERNAL MEDICINE
IL-1 beta induces dendritic cells to produce IL-12
INTERNATIONAL IMMUNOLOGY
In vitro expansion of human megakaryocytes as a tool for studying megakaryocytic development and function
PLATELETS
Very late antigen-5 and leukocyte function-associated antigen-1 are critical for early stage hematopoietic progenitor cell homing
ANNALS OF HEMATOLOGY
Establishment of serum-free pre-colony forming unit assays for differentiation of primitive hematopoietic progenitors: serum induces early macrophagedifferentiation and inhibits early erythroid differentiation of CD34(++)CD38(-) cells
ANNALS OF HEMATOLOGY
CD34+stem cell transplantation in malignancies: Report of three cases
JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION
Second transplantation with CD34(+) blood cells from an HLA-mismatched related donor after engraftment failure of transplanted cord blood cells
INTERNATIONAL JOURNAL OF HEMATOLOGY
Hematopoietic capability of CD34(+) cord blood cells: A comparison with CD34(+) adult bone marrow cells
INTERNATIONAL JOURNAL OF HEMATOLOGY
Ex vivo expansion of human hematopoietic stem cells
INTERNATIONAL JOURNAL OF HEMATOLOGY
Clinical paroxysmal nocturnal hemoglobinuria is the result of expansion ofglycosyl-phosphatidyl-inositol-anchored protein-deficient clone in the condition of deficient hematopoiesis
INTERNATIONAL JOURNAL OF HEMATOLOGY
Murine M2-10B4 and SL/SL cell lines differentially affect the balance between CD34(+) cell expansion and maturation
INTERNATIONAL JOURNAL OF HEMATOLOGY
Growth factor receptor profile of CD34(+) cells in AML and B-lineage ALL and in their normal bone marrow counterparts
EUROPEAN JOURNAL OF HAEMATOLOGY
Combination chemotherapy containing mitoguazone, ifosfamide, methotrexate,etoposide (MIME) and G-CSF efficiently mobilize peripheral blood progenitor cells in heavily pre-treated relapsed lymphoma patients
EUROPEAN JOURNAL OF HAEMATOLOGY
Efficient, long-term transgene expression in Xenopus laevis dermal melanophores
PIGMENT CELL RESEARCH
The soluble interleukin 6 receptor: mechanisms of production and implications in disease
FASEB JOURNAL
Stromal support augments extended long-term ex vivo expansion of hemopoietic progenitor cells
LEUKEMIA
TGF beta-induced SMAD2 phosphorylation predicts inhibition of thymidine incorporation in CD34(+) cells from healthy donors, but not from patients with AML after MDS
LEUKEMIA
Differential expression of chemokine receptors in B cell malignancies
LEUKEMIA
Growth advantage of chronic myeloid leukemia CFU-GM in vitro: survival to growth factor deprivation, possibly related to autocrine stimulation, is a more common feature than hypersensitivity to GM-CSF/IL3 and is efficiently counteracted by retinoids +/- alpha-interferon
LEUKEMIA
Homing, cell cycle kinetics and fate of transplanted hematopoietic stem cells
LEUKEMIA
AC133 expression in human stem cells
LEUKEMIA
Proliferating status of peripheral blood progenitor cells from patients with BCR/ABL-positive chronic myelogenous leukemia
LEUKEMIA
Proliferation and differentiation of murine haemopoietic progenitor cells in stroma-free culture in the presence of metabolites of chlorinated pesticides
TOXICOLOGY IN VITRO
Interest of cord blood stem cells
BIOMEDICINE & PHARMACOTHERAPY
CCR1 chemokine receptor expression isolates erythroid from granulocyte-macrophage progenitors
JOURNAL OF LEUKOCYTE BIOLOGY
Quantitative determination of lentiviral vector particle numbers by real-time PCR
BIOTECHNIQUES
Prospective, randomized, sequential, crossover trial of large-volume vs. normal-volume leukapheresis procedures: Effects on subpopulations of CD34(+)cells
JOURNAL OF CLINICAL APHERESIS
CD41+and CD42+hematopoietic progenitor cells may predict platelet engraftment after allogeneic peripheral blood stem cell transplantation
JOURNAL OF CLINICAL APHERESIS
Donor lymphocyte apheresis for adoptive immunotherapy compared with blood stem cell apheresis
JOURNAL OF CLINICAL APHERESIS
Importance of CD34(+) cell subsets in autologous PBSC transplantation: theMulhouse experience using CD34(+)CD38(-) cells as predictive tool for hematopoietic engraftment
JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS
Myelofibrosis with myeloid metaplasia with fatty bone marrow: report of a new case
HAEMATOLOGICA
Cyclophosphamide plus granulocyte colony stimulating factor (G-CSF) is more effective than G-CSF alone in mobilizing hemopoietic progenitor cells in severe, refractory rheumatoid arthritis
HAEMATOLOGICA
Cell cycle status of CD34+cells in human fetal bone marrow
EARLY HUMAN DEVELOPMENT
Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease
PATHOLOGIE BIOLOGIE
Human stem cell model to study signal transduction and molecular regulation mechanisms in CML
CHINESE MEDICAL JOURNAL
Tumor necrosis factor-alpha levels in long-term marrow cultures from patients with aplastic anemia: Modulation by granulocyte-macrophage colony-stimulating factor
AMERICAN JOURNAL OF HEMATOLOGY
Correlation of hematopoietic progenitor cell count determined by the SE-9000 (TM) automated hematology analyzer with CD34(+) cell count by flow cytometry in leukapheresis products
AMERICAN JOURNAL OF HEMATOLOGY
Impact of aging on immune modulation by tumor
CANCER IMMUNOLOGY IMMUNOTHERAPY
Stem cell factor protects c-kit(+) human primary erythroid cells from apoptosis
EXPERIMENTAL HEMATOLOGY
Lifelong hematopoiesis in both reconstituted and sublethally irradiated mice is provided by multiple sequentially recruited stem cells
EXPERIMENTAL HEMATOLOGY
Cell cycle activation of hematopoietic progenitor cells increases very late antigen-5-mediated adhesion to fibronectin
EXPERIMENTAL HEMATOLOGY
Differences in cell cycle kinetics of candidate engrafting cells in human bone marrow and mobilized peripheral blood
EXPERIMENTAL HEMATOLOGY
Chemokine stromal cell-derived factor-1 alpha modulates VLA-4 integrin-dependent adhesion to fibronectin and VCAM-1 on bone marrow hematopoietic progenitor cells
EXPERIMENTAL HEMATOLOGY
Combining G-CSF with a blockade of adhesion strongly improves the reconstitutive capacity of mobilized hematopoietic progenitor cells
EXPERIMENTAL HEMATOLOGY
Bone marrow stem cell protection from chemotherapy by low-molecular-weightcompounds
EXPERIMENTAL HEMATOLOGY
Mesenchymal stem cells are capable of homing to the bone marrow of non-human primates following systemic infusion
EXPERIMENTAL HEMATOLOGY
The molecular basis for the cytokine-induced defect in homing and engraftment of hematopoietic stem cells
EXPERIMENTAL HEMATOLOGY
Ex vivo expansion of hematopoietic progenitor cells and mature cells
EXPERIMENTAL HEMATOLOGY
Stem cell factor prevents Fas-mediated apoptosis of human erythroid precursor cells with Src-family kinase dependency
EXPERIMENTAL HEMATOLOGY
Murine prolactin-like protein E synergizes with human thrombopoietin to stimulate expansion of human megakaryocytes and their precursors
EXPERIMENTAL HEMATOLOGY
Ifosfamide, epirubicin and granulocyte colony-stimulating factor: A regimen for successful mobilization of peripheral blood progenitor cells in patients with multiple myeloma
HEMATOLOGICAL ONCOLOGY
Excessive T cell depletion of peripheral blood stem cells has an adverse effect upon outcome following allogeneic stem cell transplantation
BONE MARROW TRANSPLANTATION
Trafficking of CD34(+) cells into the peripheral circulation during collection of peripheral blood stem cells by apheresis
BONE MARROW TRANSPLANTATION
CD34(+) cell collection efficiency does not correlate with the pre-leukapheresis hematocrit
BONE MARROW TRANSPLANTATION
Immune reconstitution and production of intracellular cytokines in T lymphocyte populations following autologous peripheral blood stem cell transplantation
BONE MARROW TRANSPLANTATION
Glycosylated vs non-glycosylated granulocyte colony-stimulating factor (G-CSF) - results of a prospective randomised monocentre study
BONE MARROW TRANSPLANTATION
Dexamethasone, paclitaxel, etoposide, cyclophosphamide (d-TEC) and G-CSF for stem cell mobilisation in multiple myeloma
BONE MARROW TRANSPLANTATION
Storage of unprocessed G-CSF-mobilized whole blood in a modified Leibovitz's L15 medium preserves clonogenic capacity for at least 7 days
BONE MARROW TRANSPLANTATION
Similar myeloid recovery despite superior overall engraftment in NOD/SCID mice after transplantation of human CD34(+) cells from umbilical cord bloodas compared to adult sources
BONE MARROW TRANSPLANTATION
Mobilizing potential of ifosfamide/vinorelbine-based chemotherapy in pretreated malignant lymphoma
BONE MARROW TRANSPLANTATION
Kinetics of standardized large volume leukapheresis (LVL) in patients do not show a recruitment phenomenon of peripheral blood progenitor cells (PBPC)
BONE MARROW TRANSPLANTATION
Combined positive and negative cell selection from allogeneic peripheral blood progenitor cells (PBPC) by use of immunomagnetic methods
BONE MARROW TRANSPLANTATION