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La ricerca find articoli where soggetti phrase all words 'CAMPTOTHECIN' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 1330 riferimenti
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    1. Bruschi, GCM; de Souza, CC; Fagundes, MRVK; Dani, MAC; Goldman, MHS; Morris, NR; Liu, L; Goldman, GH
      Sensitivity to camptothecin in Aspergillus nidulans identifies a novel gene, scaA(+), related to the cellular DNA damage response

      MOLECULAR GENETICS AND GENOMICS
    2. Streltsov, S; Sukhanova, A; Mikheikin, A; Grokhovsky, S; Zhuze, A; Kudelina, I; Mochalov, K; Oleinikov, V; Jardillier, JC; Nabiev, I
      Structural basis of Topotecan-DNA recognition probed by flow linear dichroism, circular dichroism, and Raman spectroscopy

      JOURNAL OF PHYSICAL CHEMISTRY B
    3. Gunzburg, WH; Salmons, B
      Novel clinical strategies for the treatment of pancreatic carcinoma

      TRENDS IN MOLECULAR MEDICINE
    4. Czuwara-Ladykowska, J; Makiela, B; Smith, EA; Trojanowska, M; Rudnicka, L
      The inhibitory effects of camptothecin, a topoisomerase I inhibitor, on collagen synthesis in fibroblasts from patients with systemic sclerosis

      ARTHRITIS RESEARCH
    5. Tsai, TH
      Analytical approaches for traditional Chinese medicines exhibiting antineoplastic activity

      JOURNAL OF CHROMATOGRAPHY B
    6. Oguma, T
      Antitumor drugs possessing topoisomerase I inhibition: applicable separation methods

      JOURNAL OF CHROMATOGRAPHY B
    7. Palumbo, M; Sissi, C; Gatto, B; Moro, S; Zagotto, G
      Quantitation of camptothecin and related compounds

      JOURNAL OF CHROMATOGRAPHY B
    8. Zufia, L; Aldaz, A; Giraldez, J
      Separation methods for camptothecin and related compounds

      JOURNAL OF CHROMATOGRAPHY B
    9. Schoemaker, NE; Frigerio, E; Fraier, D; Schellens, JHM; Rosing, H; Jansen, S; Beijnen, JH
      High-performance liquid chromatographic analysis for the determination of a novel polymer-bound camptothecin derivative (MAG-camptothecin) and free camptothecin in human plasma

      JOURNAL OF CHROMATOGRAPHY B
    10. Smith, JA; Cortes, J; Newman, RA; Madden, TL
      Development of a simplified, sensitive high-performance liquid chromatographic method using fluorescence detection to determine the concentration of UCN-01 in human plasma

      JOURNAL OF CHROMATOGRAPHY B
    11. Smith, JA; Hausheer, F; Newman, RA; Madden, TL
      Development of a high-performance liquid chromatographic method to determine the concentration of karenitecin, a novel highly lipophilic camptothecinderivative, in human plasma and urine

      JOURNAL OF CHROMATOGRAPHY B
    12. Balestrieri, E; Zanier, R; Degrassi, F
      Molecular characterisation of camptothecin-induced mutations at the hprt locus in Chinese hamster cells

      MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
    13. Olsson, G; Belyaev, IY; Helleday, T; Harms-Ringdahl, M
      ELF magnetic field affects proliferation of SPD8/V79 Chinese hamster cellsbut does not interact with intrachromosomal recombination

      MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
    14. Jung, LL; Zamboni, WC
      Cellular, pharmacokinetic, and pharmacodynamic aspects of response to camptothecins: can we improve it?

      DRUG RESISTANCE UPDATES
    15. Pouliot, JJ; Robertson, CA; Nash, HA
      Pathways for repair of topoisomerase I covalent complexes in Saccharomycescerevisiae

      GENES TO CELLS
    16. Bugreev, DV; Vasyutina, EL; Ryabinin, VA; Sinyakov, AN; Buneva, VN; Nevinsky, GA
      Inhibition of human DNA topoisomerase I by new DNA minor groove ligands: Derivatives of oligo-1,3-thiazolecarboxamides

      ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT
    17. Abraham, EH; Shrivastav, B; Salikhova, AY; Sterling, KM; Johnston, N; Guidotti, G; Scala, S; Litman, T; Chan, KC; Arceci, RJ; Steiglitz, K; Herscher, L; Okunieff, P
      Cellular and biophysical evidence for interactions between adenosine triphosphate and P-glycoprotein substrates: functional implications for adenosine triphosphate/drug cotransport in P-glycoprotein overexpressing tumor cells and in P-glycoprotein low-level expressing erythrocytes

      BLOOD CELLS MOLECULES AND DISEASES
    18. Mathijssen, RHJ; van Alphen, RJ; Verweij, J; Loos, WJ; Nooter, K; Stoter, G; Sparreboom, A
      Clinical pharmacokinetics and metabolism of irinotecan (CPT-11)

      CLINICAL CANCER RESEARCH
    19. Rieber, MS; Zangemeister-Wittke, U; Rieber, M
      P53-independent induction of apoptosis in human melanoma cells by a bcl-2/bcl-xL bispecific antisense oligonucleotide

      CLINICAL CANCER RESEARCH
    20. Takimoto, CH
      Why drugs fail: Of mice and men revisited

      CLINICAL CANCER RESEARCH
    21. Blaney, S; Berg, SL; Pratt, C; Weitman, S; Sullivan, J; Luchtman-Jones, L; Bernstein, M
      A phase I study of irinotecan in pediatric patients: A Pediatric Oncology Group Study

      CLINICAL CANCER RESEARCH
    22. Jagasia, MH; Langer, CJ; Johnson, DH; Yunus, F; Rodgers, JS; Schlabach, LL; Cohen, AG; Shyr, Y; Carbone, DP; DeVore, RF
      Weekly irinotecan and cisplatin in advanced non-small cell lung cancer: A multicenter phase II study

      CLINICAL CANCER RESEARCH
    23. Li, ML; Horn, L; Firby, PS; Moore, MJ
      Pharmacological determinants of 9-aminocamptothecin cytotoxicity

      CLINICAL CANCER RESEARCH
    24. Takebayashi, Y; Goldwasser, F; Urasaki, Y; Kohlhagen, G; Pommier, Y
      Ecteinascidin 743 induces protein-linked DNA breaks in human colon carcinoma HCT116 cells and is cytotoxic independently of topoisomerase I expression

      CLINICAL CANCER RESEARCH
    25. Kanzawa, F; Koizumi, F; Koh, Y; Nakamura, T; Tatsumi, Y; Fukumoto, H; Saijo, N; Yoshioka, T; Nishio, K
      In vitro synergistic interactions between the cisplatin analogue nedaplatin and the DNA topoisomerase I inhibitor irinotecan and the mechanism of this interaction

      CLINICAL CANCER RESEARCH
    26. Scaldaferro, S; Tinelli, S; Borgnetto, ME; Azzini, A; Capranico, G
      Directed evolution to increase camptothecin sensitivity of human DNA topoisomerase I

      CHEMISTRY & BIOLOGY
    27. Thengane, SR; Kulkarni, DK; Shrikhande, VA; Krishnamurthy, KV
      Effect of thidiazuron on adventitious shoot regeneration from seedling explants of Nothapodytes foetida

      IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-PLANT
    28. Senter, PD; Beam, KS; Mixan, B; Wahl, AF
      Identification and activities of human carboxylesterases for the activation of CPT-11, a clinically approved anticancer drug

      BIOCONJUGATE CHEMISTRY
    29. Arimondo, PB; Bailly, C; Boutorine, AS; Moreau, P; Prudhomme, M; Sun, JS; Garestier, T; Helene, C
      Triple helix-forming oligonucleotides conjugated to indolocarbazole poisons direct topoisomerase I-mediated DNA cleavage to a specific site

      BIOCONJUGATE CHEMISTRY
    30. Takagi, T; Saotome, T
      Chemotherapy with irinotecan (CPT-11), a topoisomerase-I inhibitor, for refractory and relapsed non-Hodgkin's lymphoma

      LEUKEMIA & LYMPHOMA
    31. Platzer, P; Thalhammer, T; Reznicek, G; Hamilton, G; Zhang, RW; Jager, W
      Metabolism and biliary excretion of the novel anticancer agent 10-hydroxycamptothecin in the isolated perfused rat liver

      INTERNATIONAL JOURNAL OF ONCOLOGY
    32. Okamoto, R; Takano, H; Sekikawa, T; Tanaka, T; Toyada, M; Ukon, K; Tanimoto, K; Kumazaki, T; Nishiyama, M
      Unique action determinants of double acting topoisomerase inhibitor, TAS-103

      INTERNATIONAL JOURNAL OF ONCOLOGY
    33. Cosentini, E; Haberl, I; Pertschy, P; Teleky, B; Mallinger, R; Baumgartner, G; Wenzl, E; Hamilton, G
      The differentiation inducers phenylacetate and phenylbutyrate modulate camptothecin sensitivity in colon carcinoma cells in vitro by intracellular acidification

      INTERNATIONAL JOURNAL OF ONCOLOGY
    34. Smolewski, P; Grabarek, J; Phelps, DJ; Darzynkiewicz, Z
      Stathmo-apoptosis: Arresting apoptosis by fluorochrome-labeled inhibitor of caspases

      INTERNATIONAL JOURNAL OF ONCOLOGY
    35. Redkar, AA; Meadows, GG; Daoud, SS
      UCN-01 dose-dependent inhibition of normal hyperproliferative cells in mice

      INTERNATIONAL JOURNAL OF ONCOLOGY
    36. Zou, YY; Wu, QP; Tansey, W; Chow, D; Hung, MC; Vej, CC; Wallace, S; Li, C
      Effectiveness of water soluble poly(L-glutamic acid)camptothecin conjugateagainst resistant human lung cancer xenografted in nude mice

      INTERNATIONAL JOURNAL OF ONCOLOGY
    37. Lin, CF; Hsieh, PC; Lu, WD; Chiu, HF; Wu, MJ
      A series of enediynes as novel inhibitors of topoisomerase I

      BIOORGANIC & MEDICINAL CHEMISTRY
    38. Aubert, Y; Perrouault, L; Helene, C; Giovannangeli, C; Asseline, U
      Synthesis and properties of triple helix-forming oligodeoxyribonucleotidescontaining 7-chloro-7-deaza-2 '-deoxyguanosine

      BIOORGANIC & MEDICINAL CHEMISTRY
    39. Voldoire, A; Sancelme, M; Prudhomme, M; Colson, P; Houssier, C; Bailly, C; Leonce, S; Lambel, S
      Rebeccamycin analogues from indolo[2,3-c] carbazole

      BIOORGANIC & MEDICINAL CHEMISTRY
    40. Distefano, M; Ferlini, C; De Vincenzo, R; Gaggini, C; Mancuso, S; Scambia, G
      Antagonistic effect of the combination gemcitabine/topotecan in ovarian cancer cells

      ONCOLOGY RESEARCH
    41. Pessina, A; Raimondi, A; Cerri, A; Piccirillo, M; Neri, MG; Croera, C; Foti, P; Berti, E
      High sensitivity of human epidermal keratinocytes (HaCaT) to topoisomeraseinhibitors

      CELL PROLIFERATION
    42. Orlandi, L; Colella, G; Bearzatto, A; Abolafio, G; Manzotti, C; Daidone, MG; Zaffaroni, N
      Effects of a novel trinuclear platinum complex in cisplatin-sensitive and cisplatin-resistant human ovarian cancer cell lines: interference with cellcycle progression and induction of apoptosis

      EUROPEAN JOURNAL OF CANCER
    43. Boucard, M; Pinguet, F; Poujol, S; Romieu, G; Cupissol, D; Astre, C; Culine, S; Bressolle, F
      Salivary and plasma pharmacokinetics of topotecan in patients with metastatic epithelial ovarian cancer

      EUROPEAN JOURNAL OF CANCER
    44. Desjardins, JP; Abbott, EA; Emerson, DL; Tomkinson, BE; Leray, JD; Brown, EN; Hamilton, M; Dihel, L; Ptaszynski, M; Bendele, RA; Richardson, FC
      Biodistribution of NX211, liposomal lurtotecan, in tumor-bearing mice

      ANTI-CANCER DRUGS
    45. Kehrer, DFS; Soepenberg, O; Loos, WJ; Verweij, J; Sparreboom, A
      Modulation of camptothecin analogs in the treatment of cancer: a review

      ANTI-CANCER DRUGS
    46. Demarquay, D; Huchet, M; Coulomb, H; Lesueur-Ginot, L; Lavergne, O; Kasprzyk, PG; Bailly, C; Camara, J; Bigg, DCH
      The homocamptothecin BN 80915 is a highly potent orally active topoisomerase I poison

      ANTI-CANCER DRUGS
    47. Niitsu, N; Iijima, K; Chizuka, A
      Combination therapy with irinotecan (CPT-11), mitoxantrone, and dexamethasone in relapsed or refractory non-Hodgkin's lymphoma: a pilot study

      ANNALS OF HEMATOLOGY
    48. Bowman, WR; Bridge, CF; Cloonan, MO; Leach, DC
      Synthesis of heteroarenes via radical cyclisation onto nitriles

      SYNLETT
    49. Alberts, SR; Erlichman, C; Sloan, J; Okuno, SH; Burch, PA; Rubin, J; Pitot, HC; Goldberg, RM; Adjei, AA; Atherton, PJ; Kaufmann, SH
      Phase I trial of gemcitabine and CPT-11 given weekly for four weeks every six weeks

      ANNALS OF ONCOLOGY
    50. Huisman, C; Postmus, PE; Giaccone, G; Smit, EF
      A phase I study of sequential intravenous topotecan and etoposide in lung cancer patients

      ANNALS OF ONCOLOGY
    51. Rothenberg, ML; Kuhn, JG; Schaaf, LJ; Rodriguez, GI; Eckhardt, SG; Villalona-Calero, MA; Rinaldi, DA; Hammond, LA; Hodges, S; Sharma, A; Elfring, GL; Petit, RG; Locker, PK; Miller, LL; von Hoff, DD
      Phase I dose-finding and pharmacokinetic trial of irinotecan (CPT-11) administered every two weeks

      ANNALS OF ONCOLOGY
    52. Saita, T; Fujito, H; Mori, M
      Determination of topotecan by ELISA

      BIOLOGICAL & PHARMACEUTICAL BULLETIN
    53. Oguma, T; Yamada, M; Konno, T; Inukai, K; Nakaoka, M
      High-performance liquid chromatographic analysis of lactone and hydroxy acid of new antitumor drug, DX-8951 (Exatecan), in mouse plasma

      BIOLOGICAL & PHARMACEUTICAL BULLETIN
    54. Popanda, O; Flohr, C; Dai, JC; Hunzicker, A; Thielmann, HW
      A mutation in subunit B of the DNA polymerase alpha-primase complex from Novikoff hepatoma cells concomitant with a conformational change and abnormal catalytic properties of the DNA polymerase alpha-primase complex

      MOLECULAR CARCINOGENESIS
    55. Rich, TA; Kirichenko, AV
      Camptothecin schedule and timing of administration with irradiation

      ONCOLOGY-NEW YORK
    56. Vanhoefer, U; Harstrick, A; Achterrath, W; Cao, SS; Seeber, S; Rustum, YM
      Irinotecan in the treatment of colorectal cancer: Clinical overview

      JOURNAL OF CLINICAL ONCOLOGY
    57. Fisher, BJ; Scott, C; Macdonald, DR; Coughlin, C; Curran, WJ
      Phase I study of topotecan plus cranial radiation for glioblastoma multiforme: Results of Radiation Therapy Oncology Group Trial 9507

      JOURNAL OF CLINICAL ONCOLOGY
    58. Falcone, A; Di Paolo, A; Masi, G; Allegrini, G; Danesi, R; Lencioni, M; Pfanner, E; Comis, S; Del Tacca, M; Conte, P
      Sequence effect of irinotecan and fluorouracil treatment on pharmacokinetics and toxicity in chemotherapy-naive metastatic colorectal cancer patients

      JOURNAL OF CLINICAL ONCOLOGY
    59. Arimori, K; Kuroki, N; Kumamoto, A; Tanoue, N; Nakano, M; Kumazawa, E; Tohgo, A; Kikuchi, M
      Excretion into gastrointestinal tract of irinotecan lactone and carboxylate forms and their pharmacodynamics in rodents

      PHARMACEUTICAL RESEARCH
    60. Saito, K; Sudo, H; Yamazaki, M; Koseki-Nakamura, M; Kitajima, M; Takayama, H; Aimi, N
      Feasible production of camptothecin by hairy root culture of Ophiorrhiza pumila

      PLANT CELL REPORTS
    61. Nakazawa, N; Tagami, K; Iimori, H; Sano, L; Ishikawa, T; Nagao, Y
      Copper(I) iodide-promoted hydroxylation onto the lithium or potassium enolate of lactones and lactams

      HETEROCYCLES
    62. Biswas, A; Dey, J
      Ground and excited-state ionization behavior of 9-aminocamptothecin: An absorption and fluorescence spectral study

      INDIAN JOURNAL OF CHEMISTRY SECTION A-INORGANIC BIO-INORGANIC PHYSICAL THEORETICAL & ANALYTICAL CHEMISTRY
    63. Shigeoka, Y; Itoh, K; Igarashi, T; Ishizawa, K; Saeki, T; Fujii, H; Minami, H; Imoto, S; Sasaki, Y
      Clinical effect of irinotecan in advanced and metastatic breast cancer patients previously treated with doxorubicin- and docetaxel-containing regimens

      JAPANESE JOURNAL OF CLINICAL ONCOLOGY
    64. Li, TK; Liu, LF
      Tumor cell death induced by topoisomerase-targeting drugs

      ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY
    65. Canalle, R; Burim, RV; Lopes, JLC; Takahashi, CS
      Assessment of the cytotoxic and clastogenic activities of the sesquiterpene lactone lychnopholide in mammalian cells in vitro and in vivo

      CANCER DETECTION AND PREVENTION
    66. Chastagner, P; Kozin, SV; Taghian, A
      Topotecan selectively enhances the radioresponse of human small-cell lung carcinoma and glioblastoma multiforme xenografts in nude mice

      INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
    67. Bahadori, HR; Green, MR; Catapano, CV
      Synergistic interaction between topotecan and microtubule-interfering agents

      CANCER CHEMOTHERAPY AND PHARMACOLOGY
    68. Thomas, RR; Dahut, W; Harold, N; Grem, JL; Monahan, BP; Liang, M; Band, RA; Cottrell, J; Llorens, V; Smith, JA; Corse, W; Arbuck, SG; Wright, J; Chen, AP; Hamilton, JM; Allegra, CJ; Takimoto, CH
      A phase I and pharmacologic study of 9-aminocamptothecin administered as a120-h infusion weekly to adult cancer patients

      CANCER CHEMOTHERAPY AND PHARMACOLOGY
    69. Sloan, JA; Atherton, P; Reid, J; Pilot, HC; Erlichman, C; Schaaf, L
      Limited sampling models for CPT-11, SN-38, and SN-38 glucuronide

      CANCER CHEMOTHERAPY AND PHARMACOLOGY
    70. Takeda, K; Negoro, S; Takifuji, N; Nitta, T; Yoshimura, N; Terakawa, K; Fukuoka, M
      Dose escalation study of irinotecan combined with carboplatin for advancednon-small-cell lung cancer

      CANCER CHEMOTHERAPY AND PHARMACOLOGY
    71. Keir, ST; Hausheer, F; Lawless, AA; Bigner, DD; Friedman, HS
      Therapeutic activity of 7-[(2-trimethylsilyl)ethyl)]-20 (S)-camptothecin against central nervous system tumor-derived xenografts in athymic mice

      CANCER CHEMOTHERAPY AND PHARMACOLOGY
    72. Ling, YH; Donato, NJ; Perez-Soler, R
      Sensitivity to topoisomerase I inhibitors and cisplatin is associated withepidermal growth factor receptor expression in human cervical squamous carcinoma ME180 sublines

      CANCER CHEMOTHERAPY AND PHARMACOLOGY
    73. Koshkina, NV; Knight, V; Gilbert, BE; Golunski, E; Roberts, L; Waldrep, JC
      Improved respiratory delivery of the anticancer drugs, camptothecin and paclitaxel, with 5% CO2-enriched air: pharmacokinetic studies

      CANCER CHEMOTHERAPY AND PHARMACOLOGY
    74. Cholody, WM; Kosakowska-Cholody, T; Michejda, CJ
      Bisimidazoacridones induce a potent cytostatic effect in colon tumor cellsthat sensitizes them to killing by UCN-01

      CANCER CHEMOTHERAPY AND PHARMACOLOGY
    75. Soe, K; Dianov, G; Nasheuer, HP; Bohr, VA; Grosse, F; Stevnsner, T
      A human topoisomerase I cleavage complex is recognized by an additional human topisomerase I molecule in vitro

      NUCLEIC ACIDS RESEARCH
    76. Kobayashi, K; Ceryak, S; Matsuzaki, Y; Kudoh, S; Bouscarel, B
      Effect of bile acids on the uptake of irinotecan and its active metabolite, SN-38, by intestinal cells

      BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
    77. Mitani, N; Murakami, K; Yamaura, T; Ikeda, T; Saiki, I
      Inhibitory effect of berberine on the mediastinal lymph node metastasis produced by orthotopic implantation of Lewis lung carcinoma

      CANCER LETTERS
    78. Gil-Delgado, MA; Guinet, F; Castaing, D; Adam, R; Coeffic, D; Durrani, AKS; Bismuth, H; Khayat, D
      Prospective phase II trial of irinotecan, 5-fluorouracil, and leucovorin in combination as salvage therapy for advanced colorectal cancer

      AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS
    79. Burim, RV; Canalle, R; Lopes, JLC; Vichnewski, W; Takahashi, CS
      Genotoxic action of the sesquiterpene lactone centratherin on mammalian cells in vitro and in vivo

      TERATOGENESIS CARCINOGENESIS AND MUTAGENESIS
    80. Topcu, Z
      DNA topoisomerases as targets for anticancer drugs

      JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS
    81. Hanioka, N; Jinno, H; Nishimura, T; Ando, M; Ozawa, S; Sawada, J
      High-performance liquid chromatographic assay for glucuronidation activityof 7-ethyl-10-hydroxycamptothecin (SN-38), the active metabolite of irinotecan (CPT-11), in human liver microsomes

      BIOMEDICAL CHROMATOGRAPHY
    82. Oguma, T; Konno, T; Inaba, A; Nakaoka, M
      Validation study of assay method for DX-8951 and its metabolite in human plasma and urine by high-performance liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometry

      BIOMEDICAL CHROMATOGRAPHY
    83. Zhou, JJ; Liu, J; Xu, B
      Relationship between lactone ring forms of HCPT and their antitumor activities

      ACTA PHARMACOLOGICA SINICA
    84. Han, ZY; Wyche, JH; Sands, H; Pantazis, P
      9-nitrocamptothecin is an effective drug for the treatment of human lung tumors: Comparison of in vitro and in vivo studies

      ANTICANCER RESEARCH
    85. Coleman, LW; Bronstein, IB; Holden, JA
      Immunohistochemical staining for DNA topoisomerase I, DNA topoisomerase II-alpha and p53 in gastric carcinomas

      ANTICANCER RESEARCH
    86. Smolewski, P; Bedner, E; Du, LT; Hsieh, TC; Wu, JM; Phelps, DJ; Darzynkiewicz, Z
      Detection of caspases activation by fluorochrome-labeled inhibitors: Multiparameter analysis by laser scanning cytometry

      CYTOMETRY
    87. Sakuma, S; Lu, ZR; Kopeckova, P; Kopecek, J
      Biorecognizable HPMA copolymer-drug conjugates for colon-specific deliveryof 9-aminocamptothecin

      JOURNAL OF CONTROLLED RELEASE
    88. Duncan, R; Gac-Breton, S; Keane, R; Musila, R; Sat, YN; Satchi, R; Searle, F
      Polymer-drug conjugates, PDEPT and PELT: basic principles for design and transfer from the laboratory to clinic

      JOURNAL OF CONTROLLED RELEASE
    89. Greenwald, RB
      PEG drugs: an overview

      JOURNAL OF CONTROLLED RELEASE
    90. Bom, D; Curran, DP; Zhang, J; Zimmer, SG; Bevins, R; Kruszewski, S; Howe, JN; Bingcang, A; Latus, LJ; Burke, TG
      The highly lipophilic DNA topoisomerase I inhibitor DB-67 displays elevated lactone levels in human blood and potent anticancer activity

      JOURNAL OF CONTROLLED RELEASE
    91. Harada, M; Murata, J; Sakamura, Y; Sakakibara, H; Okuno, S; Suzuki, T
      Carrier and dose effects on the pharmacokinetics of T-0128, a camtothecin analogue-carboxymethyl dextran conjugate, in non-tumor- and tumor-bearing rats

      JOURNAL OF CONTROLLED RELEASE
    92. Vokes, EE; Gordon, GS; Rudin, CM; Mauer, AM; Watson, S; Krauss, S; Arrieta, R; Golomb, HM; Hoffman, PC
      A phase II trial of 9-aminocaptothecin (9-AC) as a 120-h infusion in patients with non-small cell lung cancer

      INVESTIGATIONAL NEW DRUGS
    93. Turker, L
      A theoretical study on camptothecin-AM1 treatment

      JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM
    94. Lu, CB; Fu, WM; Mattson, MP
      Telomerase protects developing neurons against DNA damage-induced cell death

      DEVELOPMENTAL BRAIN RESEARCH
    95. Hung, CL; Doniger, J; Palini, A; Snyder, SW; Radonovich, MF; Brady, JN; Pantazis, P; Sadaie, MR
      9-Nitrocamptothecin inhibits HIV-1 replication in human peripheral blood lymphocytes: A potential alternative for HIV-Infection/AIDS therapy

      JOURNAL OF MEDICAL VIROLOGY
    96. Sai, K; Kaniwa, N; Ozawa, S; Sawada, JI
      A new metabolite of irinotecan in which formation is mediated by human hepatic cytochrome P-450 3A4

      DRUG METABOLISM AND DISPOSITION
    97. Bailly, C
      DNA relaxation and cleavage assays to study topoisomerase I inhibitors

      DRUG-NUCLEIC ACID INTERACTIONS
    98. Dumas, C; Royer, J; Husson, HP
      Partial synthesis of camptothecin analogs. Part 3: Easy approach to a quinoline-lactone system

      TETRAHEDRON LETTERS
    99. Ishibashi, H; Kato, I; Takeda, Y; Tamura, O
      Synthesis of a model compound of mappicine ketone based on sulfur-directed5-exo selective aryl radical cyclization onto enamides

      TETRAHEDRON LETTERS
    100. Fulzele, DP; Satdive, RK; Pol, BB
      Growth and production of camptothecin by cell suspension cultures of Nothapodytes foetida

      PLANTA MEDICA


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Documento generato il 20/01/21 alle ore 11:56:08