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La ricerca find articoli where soggetti phrase all words 'C-TERMINAL DOMAIN' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 713 riferimenti
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    1. Weinreb, M; Machwate, M; Shir, N; Abramovitz, M; Rodan, GA; Harada, S
      Expression of the prostaglandin E-2 (PGE(2)) receptor subtype EP4 and its regulation by PGE(2) in osteoblastic cell lines and adult rat bone tissue

      BONE
    2. Chang, DY; Gu, Y; Lu, AL
      Fission yeast (Schizosaccharomyces pombe) cells defective in the MutY-homologous glycosylase activity have a mutator phenotype and are sensitive to hydrogen peroxide

      MOLECULAR GENETICS AND GENOMICS
    3. Badi, L; Barberis, A
      Proteins that genetically interact with the Saccharomyces cerevisiae transcription factor Gal11p emphasize its role in the initiation-elongation transition

      MOLECULAR GENETICS AND GENOMICS
    4. Dredge, BK; Polydorides, AD; Darnell, RB
      The splice of life: Alternative splicing and neurological disease

      NATURE REVIEWS NEUROSCIENCE
    5. Cazzulo, JJ; Stoka, V; Turk, V
      The major cysteine proteinase of Trypanosoma cruzi: A valid target for chemotherapy of Chagas disease

      CURRENT PHARMACEUTICAL DESIGN
    6. Vilmos, P; Gaudenz, K; Hegedus, Z; Marsh, JL
      The Twisted gastrulation family of proteins, together with the IGFBP and CCN families, comprise the TIC superfamily of cysteine rich secreted factors

      JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY
    7. Foda, HD; Zucker, S
      Matrix metalloproteinases in cancer invasion, metastasis and angiogenesis

      DRUG DISCOVERY TODAY
    8. Nguyen, M; Arkell, J; Jackson, CJ
      Human endothelial gelatinases and angiogenesis

      INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
    9. Dmitrieva, NI; Michea, LF; Rocha, GM; Burg, MB
      Cell cycle delay and apoptosis in response to osmotic stress

      COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR AND INTEGRATIVE PHYSIOLOGY
    10. Scanu, AM; Nakajima, K; Edelstein, C
      Apolipoprotein(a): Structure and biology

      FRONTIERS IN BIOSCIENCE
    11. Simone, C; Giordano, A
      New insight in Cdk9 function: From Tat to MyoD

      FRONTIERS IN BIOSCIENCE
    12. Segat, D; Paulsson, M; Smyth, N
      Matrilins: structure, expression and function

      OSTEOARTHRITIS AND CARTILAGE
    13. Ma, A; Richardson, A; Schaefer, EM; Parsons, JT
      Serine phosphorylation of focal adhesion kinase in interphase and mitosis:A possible role in modulating binding to p130(Cas)

      MOLECULAR BIOLOGY OF THE CELL
    14. Klezovitch, O; Scanu, AM
      Domains of apolipoprotein E involved in the binding to the protein core ofbiglycan of the vascular extracellular matrix - Potential relationship between retention and anti-atherogenic properties of this apolipoprotein

      TRENDS IN CARDIOVASCULAR MEDICINE
    15. Bakshi, RP; Galande, S; Muniyappa, K
      Functional and regulatory characteristics of eukaryotic type II DNA topoisomerase

      CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
    16. Park, GH; Lee, YT; Bae, YS
      Stimulation of human DNA topoisomerase II activity by its direct association with the beta subunit of protein kinase CKII

      MOLECULES AND CELLS
    17. Muller, SA; Engel, A
      Structure and mass analysis by scanning transmission electron microscopy

      MICRON
    18. Zvara, A; Fajardo, JE; Escalante, M; Cotton, G; Muir, T; Kirsch, KH; Birge, RB
      Activation of the focal adhesion kinase signaling pathway by structural alterations in the carboxyl-terminal region of c-Crk II

      ONCOGENE
    19. Gual, P; Giordano, S; Anguissola, S; Comoglio, PM
      Differential requirement of the last C-terminal tail of Met receptor for cell transformation and invasiveness

      ONCOGENE
    20. Yamane, K; Katayama, E; Tsuruo, T
      p53 contains a DNA break-binding motif similar to the functional part of BRCT-related region of Rb

      ONCOGENE
    21. Bernard, F; Andre, B
      Genetic analysis of the signalling pathway activated by external amino acids in Saccharomyces cerevisiae

      MOLECULAR MICROBIOLOGY
    22. Sandkvist, M
      Biology of type II secretion

      MOLECULAR MICROBIOLOGY
    23. Lloubes, R; Cascales, E; Walburger, A; Bouveret, E; Lazdunski, C; Bernadac, A; Journet, L
      The Tol-Pal proteins of the Escherichia coli cell envelope: an energized system required for outer membrane integrity?

      RESEARCH IN MICROBIOLOGY
    24. Mortier, E; Cornelissen, F; van Hove, C; Dillen, L; Richardson, A
      The focal adhesion targeting sequence is the major inhibitory moiety of Fak-related non-kinase

      CELLULAR SIGNALLING
    25. Herkel, J; Mimran, A; Erez, N; Kam, N; Lohse, AW; Marker-Hermann, E; Rotter, V; Cohen, IR
      Autoimmunity to the p53 protein is a feature of systemic lupus erythematosus (SLE) related to anti-DNA antibodies

      JOURNAL OF AUTOIMMUNITY
    26. Berke, JD; Sgambato, V; Zhu, PP; Lavoie, B; Vincent, M; Krause, M; Hyman, SE
      Dopamine and glutamate induce distinct striatal splice forms of ania-6, anRNA polymerase II-associated cyclin

      NEURON
    27. Stewart, ZA; Pietenpol, JA
      p53 signaling and cell cycle checkpoints

      CHEMICAL RESEARCH IN TOXICOLOGY
    28. Lei, EP; Krebber, H; Silver, PA
      Messenger RNAs are recruited for nuclear export during transcription

      GENES & DEVELOPMENT
    29. Fong, N; Bentley, DL
      Capping, splicing, and 3 ' processing are independently stimulated by RNA polymerase II: different functions for different segments of the CTD

      GENES & DEVELOPMENT
    30. Lins, L; Charloteaux, B; Thomas, A; Brasseur, R
      Computational study of lipid-destabilizing protein fragments: Towards a comprehensive view of tilted peptides

      PROTEINS-STRUCTURE FUNCTION AND GENETICS
    31. Ishida, R; Takashima, R; Koujin, T; Shibata, M; Nozaki, N; Seto, M; Mori, H; Haraguchi, T; Hiraoka, Y
      Mitotic specific phosphorylation of serine-1212 in human DNA topoisomeraseII alpha

      CELL STRUCTURE AND FUNCTION
    32. Cadwell, C; Zambetti, GP
      The effects of wild-type p53 tumor suppressor activity and mutant p53 gain-of-function on cell growth

      GENE
    33. Dmitrieva, N; Michea, L; Burg, M
      p53 Protects renal inner medullary cells from hypertonic stress by restricting DNA replication

      AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
    34. Gilinger, G; Bellofatto, V
      Trypanosome spliced leader RNA genes contain the first identified RNA polymerase II gene promoter in these organisms

      NUCLEIC ACIDS RESEARCH
    35. Licciardo, P; Ruggiero, L; Lania, L; Majello, B
      Transcription activation by targeted recruitment of the RNA polymerase IICTD phosphatase FCP1

      NUCLEIC ACIDS RESEARCH
    36. Van den Steen, PE; Opdenakker, G; Wormald, MR; Dwek, RA; Rudd, PM
      Matrix remodelling enzymes, the protease cascade and glycosylation

      BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
    37. Taylor, JM; Mack, CP; Nolan, K; Regan, CP; Owens, GK; Parsons, JT
      Selective expression of an endogenous inhibitor of FAK regulates proliferation and migration of vascular smooth muscle cells

      MOLECULAR AND CELLULAR BIOLOGY
    38. Goldstrohm, AC; Albrecht, TR; Sune, C; Bedford, MT; Garcia-Blanco, MA
      The transcription elongation factor CA150 interacts with RNA polymerase IIand the pre-mRNA splicing factor SF1

      MOLECULAR AND CELLULAR BIOLOGY
    39. Fan, HY; Merker, RJ; Klein, HL
      High-copy-number expression of Sub2p, a member of the RNA helicase superfamily, suppresses hpr1-mediated genomic instability

      MOLECULAR AND CELLULAR BIOLOGY
    40. Lu, ZM; Jiang, GQ; Blume-Jensen, P; Hunter, T
      Epidermal growth factor-induced tumor cell invasion and metastasis initiated by dephosphorylation and downregulation of focal adhesion kinase

      MOLECULAR AND CELLULAR BIOLOGY
    41. Hay, DC; Kemp, GD; Dargemont, C; Hay, RT
      Interaction between hnRNPA1 and I kappa B alpha is required for maximal activation of NF-kappa B-dependent transcription

      MOLECULAR AND CELLULAR BIOLOGY
    42. Yamamoto, S; Watanabe, Y; van der Spek, PJ; Watanabe, T; Fujimoto, H; Hanaoka, F; Ohkuma, Y
      Studies of nematode TFIIE function reveal a link between Ser-5 phosphorylation of RNA polymerase II and the transition from transcription initiation to elongation

      MOLECULAR AND CELLULAR BIOLOGY
    43. Scott, DB; Blanpied, TA; Swanson, GT; Zhang, C; Ehlers, MD
      An NMDA receptor ER retention signal regulated by phosphorylation and alternative splicing

      JOURNAL OF NEUROSCIENCE
    44. Sweadner, KJ; Donnet, C
      Structural similarities of Na,K-ATPase and SERCA, the Ca2+-ATPase of the sarcoplasmic reticulum

      BIOCHEMICAL JOURNAL
    45. Zhou, JM; Ahn, J; Wilson, SH; Prives, C
      A role for p53 in base excision repair

      EMBO JOURNAL
    46. Shin, M; Kang, S; Hyun, SJ; Fujita, N; Ishihama, A; Valentin-Hansen, P; Choy, HE
      Repression of deoP2 in Escherichia coli by CytR: conversion of a transcription activator into a repressor

      EMBO JOURNAL
    47. Itoh, Y; Takamura, A; Ito, N; Maru, Y; Sato, H; Suenaga, N; Aoki, T; Seiki, M
      Homophilic complex formation of MT1-MMP facilitates proMMP-2 activation onthe cell surface and promotes tumor cell invasion

      EMBO JOURNAL
    48. Rossi, DJ; Londesborough, A; Korsisaari, N; Pihlak, A; Lehtonen, E; Henkemeyer, M; Makela, TP
      Inability to enter S phase and defective RNA polymerase IICTD phosphorylation in mice lacking Mat1

      EMBO JOURNAL
    49. Wetterberg, I; Zhao, J; Masich, S; Wieslander, L; Skoglund, U
      In situ transcription and splicing in the Balbiani ring 3 gene

      EMBO JOURNAL
    50. Waltzer, L; Vandel, L; Bienz, M
      Teashirt is required for transcriptional repression mediated by high Wingless levels

      EMBO JOURNAL
    51. Daniel, EE; Jury, J; Wang, YF
      nNOS in canine lower esophageal sphincter: colocalized with Cav-1 and Ca2+-handling proteins?

      AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
    52. Wetzel, CC; Berberich, SJ
      p53 binds to cisplatin-damaged DNA

      BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION
    53. Mabuchi, A; Haga, N; Ikeda, T; Manabe, N; Ohashi, H; Takatori, Y; Nakamura, K; Ikegawa, S
      Novel mutation in exon 18 of the cartilage oligomeric matrix protein gene causes a severe pseudoachondroplasia

      AMERICAN JOURNAL OF MEDICAL GENETICS
    54. Liu, YG; Kulesz-Martin, M
      p53 protein at the hub of cellular DNA damage response pathways through sequence-specific and non-sequence-specific DNA binding

      CARCINOGENESIS
    55. Wu, ML; Chuang, YC; Chen, JP; Chen, CS; Chang, MC
      Identification and characterization of the three chitin-binding domains within the multidomain chitinase chi92 from Aeromonas hydrophila JP101

      APPLIED AND ENVIRONMENTAL MICROBIOLOGY
    56. House, PG; Volk, DE; Thiviyanathan, V; Manuel, RC; Luxon, BA; Gorenstein, DG; Lloyd, RS
      Potential double-flipping mechanism by E-coli MutY

      PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 68
    57. Roberts, GP; Thorsteinsson, MV; Kerby, RL; Lanzilotta, WN; Poulos, T
      CooA: A heme-containing regulatory protein that serves as a specific sensor of both carbon monoxide and redox state

      PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 67
    58. Paoli, M
      Protein folds propelled by diversity

      PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
    59. Ranganath, RM; Nagashree, NR
      Role of programmed cell death in development

      INTERNATIONAL REVIEW OF CYTOLOGY - A SURVEY OF CELL BIOLOGY, VOL. 202
    60. Caughey, B; Chesebro, B
      Transmissible spongiform encephalopathies and prion protein interconversions

      ADVANCES IN VIRUS RESEARCH, VOL 56
    61. Matsushita, O; Okabe, A
      Clostridial hydrolytic enzymes degrading extracellular components

      TOXICON
    62. Steinmetz, EJ; Conrad, NK; Brow, DA; Corden, JL
      RNA-binding protein Nrd1 directs poly(A)-independent 3 '-end formation of RNA polymerase II transcripts

      NATURE
    63. Welker, E; Wedemeyer, WJ; Scheraga, HA
      A role for intermolecular disulfide bonds in prion diseases?

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    64. Yu, X; Jacobs, SA; West, SC; Ogawa, T; Egelman, EH
      Domain structure and dynamics in the helical filaments formed by RecA and Rad51 on DNA

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    65. Shibata, T; Nishinaka, T; Mikawa, T; Aihara, H; Kurumizaka, H; Yokoyama, S; Ito, Y
      Homologous genetic recombination as an intrinsic dynamic property of a DNAstructure induced by RecA/Rad51-family proteins: A possible advantage of DNA over RNA as genomic material

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    66. Davies, CD; Melder, RJ; Munn, LL; Mouta-Carreira, C; Jain, RK; Boucher, Y
      Decorin inhibits endothelial migration and tube-like structure formation: Role of thrombospondin-1

      MICROVASCULAR RESEARCH
    67. Wang, D; de la Fuente, C; Deng, LW; Wang, L; Zilberman, I; Eadie, C; Healey, M; Stein, D; Denny, T; Harrison, LE; Meijer, L; Kashanchi, F
      Inhibition of human immunodeficiency virus type 1 transcription by chemical cyclin-dependent kinase inhibitors

      JOURNAL OF VIROLOGY
    68. Duschak, VG; Ciaccio, M; Nasser, JR; Basombrio, MA
      Enzymatic activity, protein expression, and gene sequence of cruzipain in virulent and attenuated Trypanosoma cruzi strains

      JOURNAL OF PARASITOLOGY
    69. Husseman, JW; Hallows, JL; Bregman, DB; Leverenz, JB; Nochlin, D; Jin, LW; Vincent, I
      Hyperphosphorylation of RNA polymerase II and reduced neuronal RNA levels precede neurofibrillary tangles in Alzheimer disease

      JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
    70. Al-Hallaq, RA; Yasuda, RP; Wolfe, BB
      Enrichment of N-methyl-D-aspartate NR1 splice variants and synaptic proteins in rat postsynaptic densities

      JOURNAL OF NEUROCHEMISTRY
    71. Stiller, JW; Riley, J; Hall, BD
      Are red algae plants? A critical evaluation of three key molecular data sets

      JOURNAL OF MOLECULAR EVOLUTION
    72. Yang, SX; VanLoock, MS; Yu, X; Egelman, EH
      Comparison of bacteriophage T4 UvsX and human Rad51 filaments suggests that RecA-like polymers may have evolved independently

      JOURNAL OF MOLECULAR BIOLOGY
    73. Lavoie, SB; Albert, AL; Handa, H; Vincent, M; Bensaude, O
      The peptidyl-prolyl isomerase Pin1 interacts with hSpt5 phosphorylated by Cdk9

      JOURNAL OF MOLECULAR BIOLOGY
    74. Keiper, T; Schneider, JG; Dugi, KA
      Novel site in lipoprotein lipase (LPL415-438) essential for substrate interaction and dimer stability

      JOURNAL OF LIPID RESEARCH
    75. Baetu, TM; Kwon, H; Sharma, S; Grandvaux, N; Hiscott, J
      Disruption of NF-kappa B signaling reveals a novel role for NF-kappa B in the regulation of TNF-related apoptosis-inducing ligand expression

      JOURNAL OF IMMUNOLOGY
    76. Chang, KC; Chuang, NN
      GTPase stimulation in shrimp Ras(Q(61)K) with geranylgeranyl pyrophosphatebut not mammalian GAP

      JOURNAL OF EXPERIMENTAL ZOOLOGY
    77. Jacotot, E; Ferri, KF; El Hamel, C; Brenner, C; Druillennec, S; Hoebeke, J; Rustin, P; Metivier, D; Lenoir, C; Geuskens, M; Vieira, HLA; Loeffler, M; Belzacq, AS; Briand, JP; Zamzami, N; Edelman, L; Xie, ZH; Reed, JC; Roques, BP; Kroemer, G
      Control of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein R and Bcl-2

      JOURNAL OF EXPERIMENTAL MEDICINE
    78. Pellizzoni, L; Charroux, B; Rappsilber, J; Mann, M; Dreyfuss, G
      A functional interaction between the survival motor neuron complex and RNApolymerase II

      JOURNAL OF CELL BIOLOGY
    79. Vila, R; Ponte, I; Collado, M; Arrondo, JLR; Jimenez, MA; Rico, M; Suau, P
      DNA-induced alpha-helical structure in the NH2-terminal domain of histone H1

      JOURNAL OF BIOLOGICAL CHEMISTRY
    80. Mendoza-Alvarez, H; Alvarez-Gonzalez, R
      Regulation of p53 sequence-specific DNA-binding by covalent poly(ADP-ribosyl)ation

      JOURNAL OF BIOLOGICAL CHEMISTRY
    81. Kumar, NV; Bernstein, LR
      Ten ERK-related proteins in three distinct classes associate with AP-1 proteins and/or AP-1 DNA

      JOURNAL OF BIOLOGICAL CHEMISTRY
    82. Wiederschain, D; Gu, JJ; Yuan, ZM
      Evidence for a distinct inhibitory factor in the regulation of p53 functional activity

      JOURNAL OF BIOLOGICAL CHEMISTRY
    83. Grigorian, M; Andresen, S; Tulchinsky, E; Kriajevska, M; Carlberg, C; Kruse, C; Cohn, M; Ambartsumian, N; Christensen, A; Selivanova, G; Lukanidin, E
      Tumor suppressor p53 protein is a new target for the metastasis-associatedMts1/S100A4 protein - Functional consequences of their interaction

      JOURNAL OF BIOLOGICAL CHEMISTRY
    84. Kumar, BRP; Swaminathan, V; Banerjee, S; Kundu, TK
      p300-mediated acetylation of human transcriptional coactivator PC4 is inhibited by phosphorylation

      JOURNAL OF BIOLOGICAL CHEMISTRY
    85. Kleifeld, O; Kotra, LP; Gervasi, DC; Brown, S; Bernardo, MM; Fridman, R; Mobashery, S; Sagi, I
      X-ray absorption studies of human matrix metalloproteinase-2 (MMP-2) boundto a highly selective mechanism-based inhibitor - Comparison with the latent and active forms of the enzyme

      JOURNAL OF BIOLOGICAL CHEMISTRY
    86. Klatt, AR; Nitsche, DP; Kobbe, B; Macht, M; Paulsson, M; Wagener, R
      Molecular structure, processing, and tissue distribution of matrilin-4

      JOURNAL OF BIOLOGICAL CHEMISTRY
    87. Brandstetter, H; Grams, F; Glitz, D; Lang, A; Huber, R; Bode, W; Krell, HW; Engh, RA
      The 1.8-angstrom crystal structure of a matrix metallaproteinase 8-barbiturate inhibitor complex reveals a previously unobserved mechanism for collagenase substrate recognition

      JOURNAL OF BIOLOGICAL CHEMISTRY
    88. Slack, DN; Seternes, OM; Gabrielsen, M; Keyse, SM
      Distinct binding determinants for ERK2/p38 alpha and JNK MAP kinases mediate catalytic activation and substrate selectivity of MAP kinase phosphatase-1

      JOURNAL OF BIOLOGICAL CHEMISTRY
    89. Woodard, RL; Lee, KJ; Huang, J; Dynan, WS
      Distinct roles for Ku protein in transcriptional reinitiation and DNA repair

      JOURNAL OF BIOLOGICAL CHEMISTRY
    90. Montesano-Roditis, L; Glitz, DG; Traut, RR; Stewart, PL
      Cryo-electron microscopic localization of protein L7/L12 within the Escherichia coli 70 S ribosome by difference mapping and Nanogold labeling

      JOURNAL OF BIOLOGICAL CHEMISTRY
    91. Degtyareva, N; Subramanian, D; Griffith, JD
      Analysis of the binding of p53 to DNAs containing mismatched and bulged bases

      JOURNAL OF BIOLOGICAL CHEMISTRY
    92. Zeng, XY; Lee, HJ; Zhang, QH; Lui, H
      p300 does not require its acetylase activity to stimulate p73 function

      JOURNAL OF BIOLOGICAL CHEMISTRY
    93. Yamaguchi, Y; Narita, T; Inukai, N; Wada, T; Handa, H
      SPT genes: Key players in the regulation of transcription, chromatin structure and other cellular processes

      JOURNAL OF BIOCHEMISTRY
    94. Li, XH; Lu, AL
      Molecular cloning and functional analysis of the MutY homolog of Deinococcus radiodurans

      JOURNAL OF BACTERIOLOGY
    95. Lohrke, SM; Yang, HJ; Jin, SG
      Reconstitution of acetosyringone-mediated Agrobacterium tumefaciens virulence gene expression in the heterologous host Escherichia coli

      JOURNAL OF BACTERIOLOGY
    96. Hefty, PS; Jolliff, SE; Caimano, MJ; Wikel, SK; Radolf, JD; Akins, DR
      Regulation of OspE-related, OspF-related, and Elp lipoproteins of Borreliaburgdorferi strain 297 by mammalian host-specific signals

      INFECTION AND IMMUNITY
    97. Betina, S; Goffrini, P; Ferrero, I; Wesolowski-Louvel, M
      RAG4 gene encodes a glucose sensor in Kluyveromyces lactis

      GENETICS
    98. Patterson, ML; Atkinson, SJ; Knauper, V; Murphy, G
      Specific collagenolysis by gelatinase A, MMP-2, is determined by the hemopexin domain and not the fibronectin-like domain

      FEBS LETTERS
    99. Cramer, P; Srebrow, A; Kadener, S; Werbajh, S; de la Mata, M; Melen, G; Nogues, G; Kornblihtt, AR
      Coordination between transcription and pre-mRNA processing

      FEBS LETTERS
    100. Ruiz, R; Ramos, JL; Egan, SM
      Interactions of the XylS regulators with the C-terminal domain of the RNA polymerase alpha subunit influence the expression level from the cognate Pmpromoter

      FEBS LETTERS


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Documento generato il 08/08/20 alle ore 23:40:07