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La ricerca find articoli where soggetti phrase all words 'BREQUINAR SODIUM' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 52 riferimenti
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    1. Kobayashi, K; Nakashima, A; Nagata, H; Nakajima, H; Yamaguchi, K; Sato, S; Miki, I
      Anti-arthritic effects of KF20444, a new immunosuppressive compound inhibiting dihydroorotate dehydrogenase, on rat collagen-induced arthritis

      INFLAMMATION RESEARCH
    2. Chujo, I; Masuda, Y; Fujino, K; Kato, S; Ogasa, T; Mohri, S; Kasai, M
      Synthetic study on novel immunosuppressant KF20444

      BIOORGANIC & MEDICINAL CHEMISTRY
    3. Seymour, L; Eisenhauer, E
      A review of dose-limiting events in phase I trials: antimetabolites show unpredictable relationships between dose and toxicity

      CANCER CHEMOTHERAPY AND PHARMACOLOGY
    4. Ullrich, A; Knecht, W; Fries, M; Loffler, M
      Recombinant expression of N-terminal truncated mutants of the membrane bound mouse, rat and human flavoenzyme dihydroorotate dehydrogenase - A versatile tool to rate inhibitor effects?

      EUROPEAN JOURNAL OF BIOCHEMISTRY
    5. Luca, ME; Paul, LC; van der Wal, AM; Bruijn, JA; de Heer, E
      Treatment with mycophenolate mofetil attenuates the development of Heymannnephritis

      EXPERIMENTAL NEPHROLOGY
    6. Liu, SP; Neidhardt, EA; Grossman, TH; Ocain, T; Clardy, J
      Structures of human dihydroorotate dehydrogenase in complex with antiproliferative agents

      STRUCTURE WITH FOLDING & DESIGN
    7. Copeland, RA; Marcinkeviciene, J; Haque, TS; Kopcho, LM; Jiang, WJ; Wang, K; Ecret, LD; Sizemore, C; Amsler, KA; Foster, L; Tadesse, S; Combs, AP; Stern, AM; Trainor, GL; Slee, A; Rogers, MJ; Hobbs, F
      Helicobacter pylori-selective antibacterials based on inhibition of pyrimidine biosynthesis

      JOURNAL OF BIOLOGICAL CHEMISTRY
    8. Batt, DG
      Inhibitors of dihydroorotate dehydrogenase

      EXPERT OPINION ON THERAPEUTIC PATENTS
    9. Ito, T; Okawa, A; Sawai, T; Yumiba, T; Maeda, A; Tori, M; Nakata, S; Nakajima, H; Sato, S; Matsuda, H
      Potent immunosuppressive effects by a newly synthesized compound KF20444

      TRANSPLANTATION PROCEEDINGS
    10. Nomura, M; Yamashita, K; Takehara, M; Omura, T; Nakajima, H; Kishida, A; Furukawa, H; Todo, S
      Effect of a new immunosuppressive agent, KF20444, in rat cardiac transplantation

      TRANSPLANTATION PROCEEDINGS
    11. BADER B; KNECHT W; FRIES M; LOFFLER M
      EXPRESSION, PURIFICATION, AND CHARACTERIZATION OF HISTIDINE-TAGGED RAT AND HUMAN FLAVOENZYME DIHYDROOROTATE DEHYDROGENASE

      Protein expression and purification (Print)
    12. WANG AX; XIE QH; LANE B; MOLLISON KW; HSIEH GC; MARSH K; SHEETS MP; LULY JR; COGHLAN MJ
      SYNTHESIS AND IMMUNOSUPPRESSANT ACTIVITY OF PYRAZOLE CARBOXAMIDES

      Bioorganic & medicinal chemistry letters
    13. Lambrigts, D; Van Calster, P; Xu, Y; Awwad, M; Neethling, FA; Kozlowski, T; Foley, A; Watts, A; Chae, SJ; Fishman, J; Thall, AD; White-Scharf, ME; Sachs, DH; Cooper, DKC
      Pharmacologic immunosuppressive therapy and extracorporeal immunoadsorption in the suppression of anti-alpha Gal antibody in the baboon

      XENOTRANSPLANTATION
    14. REN SJ; WU SK; LIEN EJ
      DIHYDROOROTATE DEHYDROGENASE INHIBITORS - QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP ANALYSIS

      Pharmaceutical research
    15. Kraft, J; Bauer, S; Keilhoff, G; Miersch, J; Wend, D; Riemann, D; Hirschelmann, R; Holzhausen, HJ; Langner, J
      Biological effects of the dihydroorotate dehydrogenase inhibitor polyporicadd, a toxic constituent of the mushroom Hapalopilus rutilans, in rats andhumans

      ARCHIVES OF TOXICOLOGY
    16. Bruneau, JM; Yea, CM; Spinella-Jaegle, S; Fudali, C; Woodward, K; Robson, PA; Sautes, C; Westwood, R; Kuo, EA; Williamson, RA; Ruuth, E
      Purification of human dihydro-orotate dehydrogenase and its inhibition by A77 1726, the active metabolite of leflunomide

      BIOCHEMICAL JOURNAL
    17. BROUARD S; BLANCHO G; MOREAU A; HESLAN JM; CUTURI MC; SOULILLOU JP
      LONG-TERM SURVIVAL OF HAMSTER-TO-RAT CARDIAC XENOGRAFTS IN THE ABSENCE OF A TH2 SHIFT

      Transplantation
    18. RUCKEMANN K; FAIRBANKS LD; CARREY EA; HAWRYLOWICZ CM; RICHARDS DF; KIRSCHBAUM B; SIMMONDS HA
      LEFLUNOMIDE INHIBITS PYRIMIDINE DE-NOVO SYNTHESIS IN MITOGEN-STIMULATED T-LYMPHOCYTES FROM HEALTHY HUMANS

      The Journal of biological chemistry
    19. JOCKEL J; WENDT B; LOFFLER M
      STRUCTURAL AND FUNCTIONAL COMPARISON OF AGENTS INTERFERING WITH DIHYDROOROTATE, SUCCINATE AND NADH OXIDATION OF RAT-LIVER MITOCHONDRIA

      Biochemical pharmacology
    20. YASUTOMI M; HAYASHI S; ITO M; OHTSUKA S; NAMII Y; UCHIDA K; YOKOYAMA I; TAKAGI H
      EVALUATION OF TETRAHYDROPYRANYLADRIAMYCIN AS AN IMMUNOSUPPRESSANT IN CONCORDANT XENOTRANSPLANTATION

      The Journal of heart and lung transplantation
    21. GOURLAY WA; MAKI T; MONACO AP
      REJECTION OF HAMSTER SKIN XENOGRAFTS BY RATS IN THE ABSENCE OF ANTI-HAMSTER ANTIBODY-FORMATION

      Xenotransplantation
    22. FIRST MR
      AN UPDATE ON NEW IMMUNOSUPPRESSIVE DRUGS UNDERGOING PRECLINICAL AND CLINICAL-TRIALS - POTENTIAL APPLICATIONS IN ORGAN-TRANSPLANTATION

      American journal of kidney diseases
    23. GORAL S; HELDERMAN JH
      EVOLUTION AND FUTURE OF IMMUNOSUPPRESSION IN RENAL-TRANSPLANTATION

      Seminars in nephrology
    24. PAPAGEORGIOU C; ZURINI M; WEBER HP; BORER X
      LEFLUNOMIDES BIOACTIVE METABOLITE HAS THE MINIMAL STRUCTURAL REQUIREMENTS FOR THE EFFICIENT INHIBITION OF HUMAN DIHYDROOROTATE DEHYDROGENASE

      Bioorganic chemistry
    25. MOR E; YUSSIM A; CHODOFF L; SCHWARTZ ME
      NEW IMMUNOSUPPRESSIVE AGENTS FOR MAINTENANCE THERAPY IN ORGAN-TRANSPLANTATION - FOCUS ON ADVERSE-EFFECTS

      Biodrugs
    26. INDUDHARA R; KHAULI RB
      KIDNEY-TRANSPLANTATION IN HIGHLY SENSITIZED PATIENTS - REAPPRAISAL OFETIOLOGY, EVALUATION, AND MANAGEMENT PROTOCOLS

      World journal of urology
    27. VANLAAR JAM; RUSTUM YM; VANDERWILT C; SMID K; KUIPER CM; PINEDO HM; PETERS GJ
      TUMOR SIZE AND ORIGIN DETERMINE THE ANTITUMOR-ACTIVITY OF CISPLATIN OR 5-FLUOROURACIL AND ITS MODULATION BY LEUCOVORIN IN MURINE COLON CARCINOMAS

      Cancer chemotherapy and pharmacology
    28. MORRIS RE
      MECHANISMS OF ACTION OF NEW IMMUNOSUPPRESSIVE DRUGS

      Kidney international
    29. SOLLINGER HW
      UPDATE ON PRECLINICAL AND CLINICAL-EXPERIENCE WITH MYCOPHENOLATE MOFETIL

      Transplantation proceedings
    30. SILVA HT; CAO W; SHORTHOUSE R; MORRIS RE
      MECHANISM OF ACTION OF LEFLUNOMIDE - IN-VIVO URIDINE ADMINISTRATION REVERSES ITS INHIBITION OF LYMPHOCYTE-PROLIFERATION

      Transplantation proceedings
    31. KNECHT W; BERGJOHANN U; GONSKI S; KIRSCHBAUM B; LOFFLER M
      FUNCTIONAL EXPRESSION OF A FRAGMENT OF HUMAN DIHYDROOROTATE DEHYDROGENASE BY MEANS OF THE BACULOVIRUS EXPRESSION VECTOR SYSTEM, AND KINETICINVESTIGATION OF THE PURIFIED RECOMBINANT ENZYME

      European journal of biochemistry
    32. DAVIS JP; CAIN GA; PITTS WJ; MAGOLDA RL; COPELAND RA
      THE IMMUNOSUPPRESSIVE METABOLITE OF LEFLUNOMIDE IS A POTENT INHIBITOROF HUMAN DIHYDROOROTATE DEHYDROGENASE

      Biochemistry
    33. XU XL; WILIAMS JW; GONG HH; FINNEGAN A; CHONG ASF
      2 ACTIVITIES OF THE IMMUNOSUPPRESSIVE METABOLITE OF LEFLUNOMIDE, A77-1726 - INHIBITION OF PYRIMIDINE NUCLEOTIDE SYNTHESIS AND PROTEIN-TYROSINE PHOSPHORYLATION

      Biochemical pharmacology
    34. CAO WW; KAO PN; CHAO AC; GARDNER P; NG J; MORRIS RE
      MECHANISM OF THE ANTIPROLIFERATIVE ACTION OF LEFLUNOMIDE - A77-1726, THE ACTIVE METABOLITE OF LEFLUNOMIDE, DOES NOT BLOCK T-CELL RECEPTOR-MEDIATED SIGNAL-TRANSDUCTION BUT ITS ANTIPROLIFERATIVE EFFECTS ARE ANTAGONIZED BY PYRIMIDINE NUCLEOSIDES

      The Journal of heart and lung transplantation
    35. CRAMER DV
      BREQUINAR SODIUM

      Pediatric nephrology
    36. GARDNER CR
      THE PHARMACOLOGY OF IMMUNOSUPPRESSANT DRUGS IN SKIN TRANSPLANT REJECTION IN MICE AND OTHER RODENTS

      General pharmacology
    37. BORIE DC; CRAMER DV; SHIRWAN H; WU GD; RODRIGUEZ O; CHAPMAN FA; MAKOWKA L
      GENETIC-CONTROL OF THE HUMORAL IMMUNE-RESPONSE TO XENOGRAFTS .2. MONOCLONAL-ANTIBODIES THAT CAUSE REJECTION OF HEART XENOGRAFTS ARE ENCODEDBY GERMLINE IMMUNOGLOBULIN GENES

      Transplantation
    38. CHERWINSKI HM; COHN RG; CHEUNG P; WEBSTER DJ; XU YZ; CAULFIELD JP; YOUNG JM; NAKANO G; RANSOM JT
      THE IMMUNOSUPPRESSANT LEFLUNOMIDE INHIBITS LYMPHOCYTE-PROLIFERATION BY INHIBITING PYRIMIDINE BIOSYNTHESIS

      The Journal of pharmacology and experimental therapeutics
    39. GREENE S; WATANABE K; BRAATZTRULSON J; LOU L
      INHIBITION OF DIHYDROOROTATE DEHYDROGENASE BY THE IMMUNOSUPPRESSIVE AGENT LEFLUNOMIDE

      Biochemical pharmacology
    40. CLEAVELAND ES; MONKS A; VAIGROWOLFF A; ZAHAREVITZ DW; PAULL K; ARDALAN K; COONEY DA; FORD H
      SITE OF ACTION OF 2 NOVEL PYRIMIDINE BIOSYNTHESIS INHIBITORS ACCURATELY PREDICTED BY THE COMPARE PROGRAM

      Biochemical pharmacology
    41. COPELAND RA; DAVIS JP; DOWLING RL; LOMBARDO D; MURPHY KB; PATTERSON TA
      RECOMBINANT HUMAN DIHYDROOROTATE DEHYDROGENASE - EXPRESSION, PURIFICATION, AND CHARACTERIZATION OF A CATALYTICALLY FUNCTIONAL TRUNCATED ENZYME

      Archives of biochemistry and biophysics
    42. KUUSREICHEL K; GRAUER LS; KARAVODIN LM; KNOTT C; KRUSEMEIER M; KAY NE
      WILL IMMUNOGENICITY LIMIT THE USE, EFFICACY, AND FUTURE-DEVELOPMENT OF THERAPEUTIC MONOCLONAL-ANTIBODIES

      Clinical and diagnostic laboratory immunology
    43. HAYDON GH; HAYES PC
      NEW IMMUNOSUPPRESSIVE TREATMENT IN TRANSPLANTATION MEDICINE

      Bailliere's clinical gastroenterology
    44. ALEXANDER JW; MASROOR S; LEVY A; GALLA K
      A NEW STRATEGY FOR PROLONGING XENOGRAFT SURVIVAL

      Transplantation
    45. KNIGHT RJ; KURRLE R; STEPKOWSKI S; SERINO F; CHOU TC; KAHAN BD
      SYNERGISTIC IMMUNOSUPPRESSIVE ACTIONS OF CYCLOSPORINE WITH A MOUSE ANTI-RAT ALPHA BETA-T-CELL RECEPTOR MONOCLONAL-ANTIBODY/

      Transplantation
    46. KNOOP M; PRATT JR; HUTCHINSON IV
      EVIDENCE OF ALLOREACTIVE T-SUPPRESSOR CELLS IN THE MAINTENANCE PHASE OF SPONTANEOUS TOLERANCE AFTER ORTHOTOPIC LIVER-TRANSPLANTATION IN THERAT

      Transplantation
    47. KAHAN BD; GHOBRIAL R
      IMMUNOSUPPRESSIVE AGENTS

      The Surgical clinics of North America
    48. HIRST M; HALIDAY E; NAKAMURA J; LOU L
      HUMAN GMP SYNTHETASE - PROTEIN-PURIFICATION, CLONING, AND FUNCTIONAL EXPRESSION OF CDNA

      The Journal of biological chemistry
    49. YATSCOFF RW
      LABORATORY SUPPORT FOR TRANSPLANTATION

      Clinical chemistry
    50. COSTANZONORDIN MR; COOPER DKC; JESSUP M; RENLUND DG; ROBINSON JA; ROSE EA
      TASK FORCE-6 - FUTURE-DEVELOPMENTS

      Journal of the American College of Cardiology
    51. CODY R; STEWART D; DEFORNI M; MOORE M; DALLAIRE B; AZARNIA N; GYVES J
      MULTICENTER PHASE-II STUDY OF BREQUINAR SODIUM IN PATIENTS WITH ADVANCED BREAST-CANCER

      American journal of clinical oncology
    52. MOORE M; MAROUN J; ROBERT F; NATALE R; NEIDHART J; DALLAIRE B; SISK R; GYVES J
      MULTICENTER PHASE-II STUDY OF BREQUINAR SODIUM IN PATIENTS WITH ADVANCED GASTROINTESTINAL CANCER

      Investigational new drugs


ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/21 alle ore 02:25:57