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La ricerca find articoli where soggetti phrase all words 'BIOSYNTHETIC GENE-CLUSTER' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 80 riferimenti
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    1. Holzer, M; Burd, W; Reissig, HU; van Pee, KH
      Substrate specificity and regioselectivity of tryptophan 7-halogenase fromPseudomonas fluorescens BL915

      ADVANCED SYNTHESIS & CATALYSIS
    2. Thorson, JS; Hosted, TJ; Jiang, JQ; Biggins, JB; Ahlert, J
      Nature's carbohydrate chemists: The enzymatic glycosylation of bioactive bacterial metabolites

      CURRENT ORGANIC CHEMISTRY
    3. Walsh, CT; Chen, HW; Keating, TA; Hubbard, BK; Losey, HC; Luo, LS; Marshall, CG; Miller, DA; Patel, HM
      Tailoring enzymes that modify nonribosomal peptides during and after chainelongation on NRPS assembly lines

      CURRENT OPINION IN CHEMICAL BIOLOGY
    4. Ikeda, H; Nonomiya, T; Omura, S
      Organization of biosynthetic gene cluster for avermectin in Streptomyces avermitilis: analysis of enzymatic domains in four polyketide synthases

      JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
    5. Butler, AR; Cundliffe, E
      Influence of dimethylsulfoxide on tylosin production in Streptomyces fradiae

      JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
    6. Florsheimer, A; Altmann, KH
      Epothilones and their analogues - a new class of promising microtubule inhibitors

      EXPERT OPINION ON THERAPEUTIC PATENTS
    7. Rowe, CJ; Bohm, IU; Thomas, IP; Wilkinson, B; Rudd, BAM; Foster, G; Blackaby, AP; Sidebottom, PJ; Roddis, Y; Buss, AD; Staunton, J; Leadlay, PF
      Engineering a polyketide with a longer chain by insertion of an extra module into the erythromycin-producing polyketide synthase

      CHEMISTRY & BIOLOGY
    8. Holzbaur, IE; Ranganathan, A; Thomas, IP; Kearney, DJA; Reather, JA; Rudd, BAM; Staunton, J; Leadlay, PF
      Molecular basis of Celmer's rules: role of the ketosynthase domain in epimerisation and demonstration that ketoreductase domains can have altered product specificity with unnatural substrates

      CHEMISTRY & BIOLOGY
    9. Blanco, G; Patallo, EP; Brana, AF; Trefzer, A; Bechthold, A; Rohr, J; Mendez, C; Salas, JA
      Identification of a sugar flexible glycosyltransferase from Streptomyces olivaceus, the producer of the antitumor polyketide elloramycin

      CHEMISTRY & BIOLOGY
    10. Silakowski, B; Nordsiek, G; Kunze, B; Blocker, H; Muller, R
      Novel features in a combined polyketide synthase/non-ribosomal peptide synthetase: the myxalamid biosynthetic gene cluster of the myxobacterium Stigmatella aurantiaca Sga15

      CHEMISTRY & BIOLOGY
    11. Mendez, C; Salas, JA
      The role of ABC transporters in antibiotic-producing organisms: drug secretion and resistance mechanisms

      RESEARCH IN MICROBIOLOGY
    12. Jiralerspong, S; Rangaswamy, V; Bender, CL; Parry, RJ
      Analysis of the enzymatic domains in the modular portion of the coronafacic acid polyketide synthase

      GENE
    13. Bugg, TDH
      The development of mechanistic enzymology in the 20th century

      NATURAL PRODUCT REPORTS
    14. Mendez, C; Salas, JA
      Altering the glycosylation pattern of bioactive compounds

      TRENDS IN BIOTECHNOLOGY
    15. Hardt, IH; Steinmetz, H; Gerth, K; Sasse, F; Reichenbach, H; Hofle, G
      New natural epothilones from Sorangium cellulosum, strains So ce90/B2 and So ce90/D13: Isolation, structure elucidation, and SAR studies

      JOURNAL OF NATURAL PRODUCTS
    16. Omura, S; Ikeda, H; Ishikawa, J; Hanamoto, A; Takahashi, C; Shinose, M; Takahashi, Y; Horikawa, H; Nakazawa, H; Osonoe, T; Kikuchi, H; Shiba, T; Sakaki, Y; Hattori, M
      Genome sequence of an industrial microorganism Streptomyces avermitilis: Deducing the ability of producing secondary metabolites

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    17. Nivens, DE; Ohman, DE; Williams, J; Franklin, MJ
      Role of alginate and its O acetylation in formation of Pseudomonas aeruginosa microcolonies and biofilms

      JOURNAL OF BACTERIOLOGY
    18. Pier, GB; Coleman, F; Grout, M; Franklin, M; Ohman, DE
      Role of alginate O acetylation in resistance of mucoid Pseudomonas aeruginosa to opsonic phagocytosis

      INFECTION AND IMMUNITY
    19. Chen, HW; Thomas, MG; O'Connor, SE; Hubbard, BK; Burkart, MD; Walsh, CT
      Aminoacyl-S-enzyme intermediates in beta-hydroxylations and alpha,beta-desaturations of amino acids in peptide antibiotics

      BIOCHEMISTRY
    20. Patel, HM; Walsh, CT
      In vitro reconstitution of the Pseudomonas aeruginosa nonribosomal peptidesynthesis of pyochelin: Characterization of backbone tailoring thiazoline reductase and N-methyltransferase activities

      BIOCHEMISTRY
    21. Admiraal, SJ; Walsh, CT; Khosla, C
      The loading module of rifamycin synthetase is an adenylation-thiolation didomain with substrate tolerance for substituted benzoates

      BIOCHEMISTRY
    22. Miller, DA; Walsh, CT; Luo, LS
      C-methyltransferase and cyclization domain activity at the intraprotein PK/NRP switch point of yersiniabactin synthetase

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    23. Lee, CB; Wu, ZC; Zhang, F; Chappell, MD; Stachel, SJ; Chou, TC; Guan, YB; Danishefsky, SJ
      Insights into long-range structural effects on the stereochemistry of aldol condensations: A practical total synthesis of desoxyepothilone F

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    24. Keller, S; Wage, T; Hohaus, K; Holzer, M; Eichhorn, E; van Pee, KH
      Purification and partial characterization of tryptophan 7-halogenase (PrnA) from Pseudomonas fluorescens

      ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
    25. Thorson, JS; Sievers, EL; Ahlert, J; Shepard, E; Whitwam, RE; Onwueme, KC; Ruppen, M
      Understanding and exploiting nature's chemical arsenal: The past, present and future of calicheamicin research

      CURRENT PHARMACEUTICAL DESIGN
    26. Kaneko, T; McArthur, H; Sutcliffe, J
      Recent developments in the area of macrolide antibiotics

      EXPERT OPINION ON THERAPEUTIC PATENTS
    27. Sosio, M; Giusino, F; Cappellano, C; Bossi, E; Puglia, AM; Donadio, S
      Artificial chromosomes for antibiotic-producing actinomycetes

      NATURE BIOTECHNOLOGY
    28. Wilkinson, B; Foster, G; Rudd, BAM; Taylor, NL; Blackaby, AP; Sidebottom, PJ; Cooper, DJ; Dawson, MJ; Buss, AD; Gaisser, S; Bohm, IU; Rowe, CJ; Cortes, J; Leadlay, PF; Staunton, J
      Novel octaketide macrolides related to 6-deoxyerythronolide B provide evidence for iterative operation of the erythromycin polyketide synthase

      CHEMISTRY & BIOLOGY
    29. Chen, S; Xue, YQ; Sherman, DH; Reynolds, KA
      Mechanisms of molecular recognition in the pikromycin polyketide synthase

      CHEMISTRY & BIOLOGY
    30. Haas, D; Blumer, C; Keel, C
      Biocontrol ability of fluorescent pseudomonads genetically dissected: importance of positive feedback regulation

      CURRENT OPINION IN BIOTECHNOLOGY
    31. Morita, N; Tanaka, M; Okuyama, H
      Biosynthesis of fatty acids in the docosahexaenoic acid-producing bacterium Moritella marina strain MP-I

      BIOCHEMICAL SOCIETY TRANSACTIONS
    32. Patterson, JH; McConville, MJ; Haites, RE; Coppel, RL; Billman-Jacobe, H
      Identification of a methyltransferase from Mycobacterium smegmatis involved in glycopeptidolipid synthesis

      JOURNAL OF BIOLOGICAL CHEMISTRY
    33. Preston, LA; Wong, TY; Bender, CL; Schiller, NL
      Characterization of alginate lyase from Pseudomonas syringae pv. syringae

      JOURNAL OF BACTERIOLOGY
    34. Quiros, LM; Carbajo, RJ; Salas, JA
      Inversion of the anomeric configuration of the transferred sugar during inactivation of the macrolide antibiotic oleandomycin catalyzed by a macrolide glycosyltransferase

      FEBS LETTERS
    35. Bycroft, M; Weissman, KJ; Staunton, J; Leadlay, PF
      Efficient purification and kinetic characterization of a bimodular derivative of the erythromycin polyketide synthase

      EUROPEAN JOURNAL OF BIOCHEMISTRY
    36. He, XM; Agnihotri, G; Liu, HW
      Novel enzymatic mechanisms in carbohydrate metabolism

      CHEMICAL REVIEWS
    37. Guder, A; Wiedemann, I; Sahl, HG
      Posttranslationally modified bacteriocins - The lantibiotics

      BIOPOLYMERS
    38. Arndt, C; Cruz, MC; Cardenas, ME; Heitman, J
      Secretion of FK506/FK520 and rapamycin by Streptomyces inhibits the growthof competing Saccharomyces cerevisiae and Cryptococcus neoformans

      MICROBIOLOGY-UK
    39. Olano, C; Lomovskaya, N; Fonstein, L; Roll, JT; Hutchinson, CR
      A two-plasmid system for the glycosylation of polyketide antibiotics: bioconversion of epsilon-rhodomycinone to rhodomycin D

      CHEMISTRY & BIOLOGY
    40. Ranganathan, A; Timoney, M; Bycroft, M; Cortes, J; Thomas, IP; Wilkinson, B; Kellenberger, L; Hanefeld, U; Galloway, IS; Staunton, J; Leadlay, PF
      Knowledge-based design of bimodular and trimodular polyketide synthases based on domain and module swaps: a route to simple statin analogues

      CHEMISTRY & BIOLOGY
    41. Weissman, KJ; Kearney, GC; Leadlay, PF; Staunton, J
      Structural elucidation studies of polyketide tetrasubstituted delta-lactones by gas chromatography/tandem mass spectrometry and electrospray mass spectrometry

      RAPID COMMUNICATIONS IN MASS SPECTROMETRY
    42. Yu, J; Penaloza-Vazquez, A; Chakrabarty, AM; Bender, CL
      Involvement of the exopolysaccharide alginate in the virulence and epiphytic fitness of Pseudomonas syringae pv. syringae

      MOLECULAR MICROBIOLOGY
    43. Westrich, L; Domann, S; Faust, B; Bedford, D; Hopwood, DA; Bechthold, A
      Cloning and characterization of a gene cluster from Streptomyces cyanogenus S136 probably involved in landomycin biosynthesis

      FEMS MICROBIOLOGY LETTERS
    44. Khosla, C; Gokhale, RS; Jacobsen, JR; Cane, DE
      Tolerance and specificity of polyketide synthases

      ANNUAL REVIEW OF BIOCHEMISTRY
    45. Xue, Q; Ashley, G; Hutchinson, CR; Santi, DV
      A multiplasmid approach to preparing large libraries of polyketides

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    46. Gao, GH; Nara, T; Nakajima-Shimada, J; Aoki, T
      Novel organization and sequences of five genes encoding all six enzymes for de novo pyrimidine biosynthesis in Trypanosoma cruzi

      JOURNAL OF MOLECULAR BIOLOGY
    47. Keith, LMW; Bender, CL
      A1gT (sigma(22)) controls alginate production and tolerance to environmental stress in Pseudomonas syringae

      JOURNAL OF BACTERIOLOGY
    48. Witkowski, A; Joshi, AK; Lindqvist, Y; Smith, S
      Conversion of a beta-ketoacyl synthase to a malonyl decarboxylase by replacement of the active-site cysteine with glutamine

      BIOCHEMISTRY
    49. Hallis, TM; Liu, HW
      Learning nature's strategies for making deoxy sugars: Pathways, mechanisms, and combinatorial applications

      ACCOUNTS OF CHEMICAL RESEARCH
    50. English, RS; Lampel, JS; Vanden Boom, TJ
      Transformation of Saccharopolyspora erythraea by electroporation of germinating spores: construction of propionyl Co-A carboxylase mutants

      JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
    51. BOHM I; HOLZBAUR IE; HANEFELD U; CORTES J; STAUNTON J; LEADLAY PF
      ENGINEERING OF A MINIMAL MODULAR POLYKETIDE SYNTHASE, AND TARGETED ALTERATION OF THE STEREOSPECIFICITY OF POLYKETIDE CHAIN EXTENSION

      Chemistry & biology
    52. XUE YQ; WILSON D; ZHAO LS; LIU HW; SHERMAN DH
      HYDROXYLATION OF MACROLACTONES YC-17 AND NARBOMYCIN IS MEDIATED BY THE PIKC-ENCODED CYTOCHROME-P450 IN STREPTOMYCES-VENEZUELAE

      Chemistry & biology
    53. Kamath, S; Kapatral, V; Chakrabarty, AM
      Cellular function of elastase in Pseudomonas aeruginosa: role in the cleavage of nucleoside diphosphate kinase and in alginate synthesis

      MOLECULAR MICROBIOLOGY
    54. ROWE CJ; CORTES J; GAISSER S; STAUNTON J; LEADLEY PF
      CONSTRUCTION OF NEW VECTORS FOR HIGH-LEVEL EXPRESSION IN ACTINOMYCETES

      Gene
    55. MARSDEN AFA; WILKINSON B; CORTES J; DUNSTER NJ; STAUNTON J; LEADLAY PF
      ENGINEERING BROADER SPECIFICITY INTO AN ANTIBIOTIC-PRODUCING POLYKETIDE SYNTHASE

      Science
    56. JAIN S; OHMAN DE
      DELETION OF ALGK IN MUCOID PSEUDOMONAS-AERUGINOSA BLOCKS ALGINATE POLYMER FORMATION AND RESULTS IN URONIC-ACID SECRETION

      Journal of bacteriology
    57. KIMURA M; MATSUMOTO G; SHINGU Y; YONEYAMA K; YAMAGUCHI I
      THE MYSTERY OF THE TRICHOTHECENE 3-O-ACETYLTRANSFERASE GENE - ANALYSIS OF THE REGION AROUND TRI101 AND CHARACTERIZATION OF ITS HOMOLOG FROMFUSARIUM-SPOROTRICHIOIDES

      FEBS letters
    58. TERCERO JA; ESPINOSA JC; JIMENEZ A
      EXPRESSION OF THE STREPTOMYCES-ALBONIGER PUR CLUSTER IN STREPTOMYCES-LIVIDANS IS DEPENDENT ON THE BLDA-ENCODED TRNA(LEU)

      FEBS letters
    59. WATANABE CMH; TOWNSEND CA
      THE IN-VITRO CONVERSION OF NORSOLORINIC ACID TO AFLATOXIN B-1 - AN IMPROVED METHOD OF CELL-FREE ENZYME PREPARATION AND STABILIZATION

      Journal of the American Chemical Society
    60. KAO CM; MCPHERSON M; MCDANIEL RN; FU H; CANE DE; KHOSLA C
      ALCOHOL STEREOCHEMISTRY IN POLYKETIDE BACKBONES IS CONTROLLED BY THE BETA-KETOREDUCTASE DOMAINS OF MODULAR POLYKETIDE SYNTHASES

      Journal of the American Chemical Society
    61. KOJIMA I; DEMAIN AL
      PREFERENTIAL PRODUCTION OF RAPAMYCIN VS PROLYLRAPAMYCIN BY STREPTOMYCES-HYGROSCOPICUS

      Journal of industrial microbiology & biotechnology
    62. BYSTRYKH LV; HERREMA JK; KRUIZINGA W; KELLOGG RM
      5-HYDROXYALOESAPONARIN-II, A MINOR BLUE PIGMENT IN AN ACTINORHODIN-NEGATIVE MUTANT OF STREPTOMYCES-COELICOLOR A3(2)

      Biotechnology and applied biochemistry
    63. FLOSS HG
      NATURAL-PRODUCTS DERIVED FROM UNUSUAL VARIANTS OF THE SHIKIMATE PATHWAY

      Natural product reports
    64. RUAN X; PEREDA A; STASSI DL; ZEIDNER D; SUMMERS RG; JACKSON M; SHIVAKUMAR A; KAKAVAS S; STAVER MJ; DONADIO S; KATZ L
      ACYLTRANSFERASE DOMAIN SUBSTITUTIONS IN ERYTHROMYCIN POLYKETIDE SYNTHASE YIELD NOVEL ERYTHROMYCIN DERIVATIVES

      Journal of bacteriology
    65. MATHEE K; MCPHERSON CJ; OHMAN DE
      POSTTRANSLATIONAL CONTROL OF THE ALGT (ALGU)-ENCODED SIGMA(22) FOR EXPRESSION OF THE ALGINATE REGULON IN PSEUDOMONAS-AERUGINOSA AND LOCALIZATION OF ITS ANTAGONIST PROTEINS MUCA AND MUCB (ALGN)

      Journal of bacteriology
    66. JANECEK J; TICHY P; SPIZEK J; VANEK Z
      CONSTITUTION OF THE METABOLIC TYPE OF STREPTOMYCETES DURING THE FIRSTHOURS OF CULTIVATION

      Folia microbiologica
    67. KATZ L
      MANIPULATION OF MODULAR POLYKETIDE SYNTHESES

      Chemical reviews
    68. MARAHIEL MA; STACHELHAUS T; MOOTZ HD
      MODULAR PEPTIDE SYNTHETASES INVOLVED IN NONRIBOSOMAL PEPTIDE-SYNTHESIS

      Chemical reviews
    69. WEISSMAN KJ; TIMONEY M; BYCROFT M; GRICE P; HANEFELD U; STAUNTON J; LEADLAY PF
      THE MOLECULAR-BASIS OF CELMERS RULES - THE STEREOCHEMISTRY OF THE CONDENSATION STEP IN CHAIN EXTENSION ON THE ERYTHROMYCIN POLYKETIDE SYNTHASE

      Biochemistry
    70. LAL R; KHANNA R; KAUR H; KHANNA M; DHINGRA N; LAL S; GARTEMANN KH; EICHENLAUB R; GHOSH PK
      ENGINEERING ANTIBIOTIC PRODUCERS TO OVERCOME THE LIMITATIONS OF CLASSICAL STRAIN IMPROVEMENT PROGRAMS

      Critical reviews in microbiology
    71. GOVAN JRW; DERETIC V
      MICROBIAL PATHOGENESIS IN CYSTIC-FIBROSIS - MUCOID PSEUDOMONAS-AERUGINOSA AND BURKHOLDERIA-CEPACIA

      Microbiological reviews
    72. SHEN B; HUTCHINSON CR
      DECIPHERING THE MECHANISM FOR THE ASSEMBLY OF AROMATIC POLYKETIDES BYA BACTERIAL POLYKETIDE SYNTHASE

      Proceedings of the National Academy of Sciences of the United Statesof America
    73. MONDAY SR; SCHILLER NL
      ALGINATE SYNTHESIS IN PSEUDOMONAS-AERUGINOSA - THE ROLE OF ALGL (ALGINATE LYASE) AND ALGX

      Journal of bacteriology
    74. BOYD A; CHAKRABARTY AM
      PSEUDOMONAS-AERUGINOSA BIOFILMS - ROLE OF THE ALGINATE EXOPOLYSACCHARIDE

      Journal of industrial microbiology
    75. SUTHERLAND IW
      POLYSACCHARIDE LYASES

      FEMS microbiology reviews
    76. MEURER G; HUTCHINSON CR
      FUNCTIONAL-ANALYSIS OF PUTATIVE BETA-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE AND ACYLTRANSFERASE ACTIVE-SITE MOTIFS IN A TYPE-II POLYKETIDE SYNTHASE OF STREPTOMYCES-GLAUCESCENS

      Journal of bacteriology
    77. MEYER C; BIERBAUM G; HEIDRICH C; REIS M; SULING J; IGLESIASWIND MI; KEMPTER C; MOLITOR E; SAHL HG
      NUCLEOTIDE-SEQUENCE OF THE LANTIBIOTIC PEP5 BIOSYNTHETIC GENE-CLUSTERAND FUNCTIONAL-ANALYSIS OF PEPP AND PEPC - EVIDENCE FOR A ROLE OF PEPC IN THIOETHER FORMATION

      European journal of biochemistry
    78. MEURER G; HUTCHINSON CR
      DAUNORUBICIN TYPE-II POLYKETIDE SYNTHASE ENZYMES DPSA AND DPSB DETERMINE NEITHER THE CHOICE OF STARTER UNIT NOR THE CYCLIZATION PATTERN OF AROMATIC POLYKETIDES

      Journal of the American Chemical Society
    79. DEVRIES CA; OHMAN DE
      MUCOID-TO-NONMUCOID CONVERSION IN ALGINATE-PRODUCING PSEUDOMONAS-AERUGINOSA OFTEN RESULTS FROM SPONTANEOUS MUTATIONS IN ALGT, ENCODING A PUTATIVE ALTERNATE SIGMA-FACTOR, AND SHOWS EVIDENCE FOR AUTOREGULATION

      Journal of bacteriology
    80. DEVRIES CA; OHMAN DE
      MUCOID-TO-NONMUCOID CONVERSION IN ALGINATE-PRODUCING PSEUDOMONAS-AERUGINOSA OFTEN RESULTS FROM SPONTANEOUS MUTATIONS IN ALGT, ENCODING A PUTATIVE ALTERNATE SIGMA-FACTOR, AND SHOWS EVIDENCE FOR AUTOREGULATION

      Journal of bacteriology


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Documento generato il 19/01/21 alle ore 19:58:04