Le informazioni sugli articoli di fonte ISI sono coperte da copyright

Per ulteriori informazioni selezionare i riferimenti di interesse.

1. Javitch, JA; Shi, L; Liapakis, G
   Use of the substituted cysteine accessibility method to study the structure and function of G protein-coupled receptors
   G PROTEIN PATHWAYS, PT A, RECEPTORS
   
   J.A. Javitch et al., "Use of the substituted cysteine accessibility method to study the structure and function of G protein-coupled receptors", METH ENZYM, 343, 2002, pp. 137-156
2. Visiers, I; Ballesteros, JA; Weinstein, H
   Three-dimensional representations of G protein-coupled receptor structuresand mechanisms
   G PROTEIN PATHWAYS, PT A, RECEPTORS
   
   I. Visiers et al., "Three-dimensional representations of G protein-coupled receptor structuresand mechanisms", METH ENZYM, 343, 2002, pp. 329-371
3. Huang, XM; Lawler, CP; Lewis, MM; Nichols, DE; Mailman, RB
   D-1 dopamine receptors
   INTERNATIONAL REVIEW OF NEUROBIOLOGY, VOL 48
   
   X.M. Huang et al., "D-1 dopamine receptors", INT R NEURO, 48, 2001, pp. 65-139
4. Whitehead, RE; Ferrer, JV; Javitch, JA; Justice, JB
   Reaction of oxidized dopamine with endogenous cysteine residues in the human dopamine transporter
   JOURNAL OF NEUROCHEMISTRY
   
   R.E. Whitehead et al., "Reaction of oxidized dopamine with endogenous cysteine residues in the human dopamine transporter", J NEUROCHEM, 76(4), 2001, pp. 1242-1251
5. Da Settimo, F; Primofiore, G; Taliani, S; Marini, AM; La Motta, C; Novellino, E; Greco, G; Lavecchia, A; Trincavelli, L; Martini, C
   3-aryl[1,2,4]triazino[4,3-alpha]benzimidazol-4(10H)-ones: A new class of selective A(1) adenosine receptor antagonists
   JOURNAL OF MEDICINAL CHEMISTRY
   
   F. Da Settimo et al., "3-aryl[1,2,4]triazino[4,3-alpha]benzimidazol-4(10H)-ones: A new class of selective A(1) adenosine receptor antagonists", J MED CHEM, 44(3), 2001, pp. 316-327
6. Blaney, FE; Raveglia, LF; Artico, M; Cavagnera, S; Dartois, C; Farina, C; Grugni, M; Gagliardi, S; Luttmann, MA; Martinelli, M; Nadler, GMMG; Parini, C; Petrillo, P; Sarau, HM; Scheideler, MA; Hay, DWP; Giardina, GAM
   Stepwise modulation of neurokinin-3 and neurokinin-2 receptor affinity andselectivity in quinoline tachykinin receptor antagonists
   JOURNAL OF MEDICINAL CHEMISTRY
   
   F.E. Blaney et al., "Stepwise modulation of neurokinin-3 and neurokinin-2 receptor affinity andselectivity in quinoline tachykinin receptor antagonists", J MED CHEM, 44(11), 2001, pp. 1675-1689
7. Govaerts, C; Blanpain, C; Deupi, X; Ballet, S; Ballesteros, JA; Wodak, SJ; Vassart, G; Pardo, L; Parmentier, M
   The TXP motif in the second transmembrane helix of CCR5 - A structural determinant of chemokine-induced activation
   JOURNAL OF BIOLOGICAL CHEMISTRY
   
   C. Govaerts et al., "The TXP motif in the second transmembrane helix of CCR5 - A structural determinant of chemokine-induced activation", J BIOL CHEM, 276(16), 2001, pp. 13217-13225
8. Sealfon, SC
   Dopamine receptors and locomotor responses: Molecular aspects
   ANNALS OF NEUROLOGY
   
   S.C. Sealfon, "Dopamine receptors and locomotor responses: Molecular aspects", ANN NEUROL, 47(4), 2000, pp. S12-S21
9. Blaker, M; Ren, Y; Seshadri, L; McBride, EW; Beinborn, M; Kopin, AS
   CCK-B/gastrin receptor transmembrane domain mutations selectively alter synthetic agonist efficacy without affecting the activity of endogenous peptides
   MOLECULAR PHARMACOLOGY
   
   M. Blaker et al., "CCK-B/gastrin receptor transmembrane domain mutations selectively alter synthetic agonist efficacy without affecting the activity of endogenous peptides", MOLEC PHARM, 58(2), 2000, pp. 399-406
10. Schetz, JA; Benjamin, PS; Sibley, DR
    Nonconserved residues in the second transmembrane-spanning domain of the D-4 dopamine receptor are molecular determinants of D-4-selective pharmacology
    MOLECULAR PHARMACOLOGY
    
    J.A. Schetz et al., "Nonconserved residues in the second transmembrane-spanning domain of the D-4 dopamine receptor are molecular determinants of D-4-selective pharmacology", MOLEC PHARM, 57(1), 2000, pp. 144-152
11. Fanelli, F
    Theoretical study on mutation-induced activation of the luteinizing hormone receptor
    JOURNAL OF MOLECULAR BIOLOGY
    
    F. Fanelli, "Theoretical study on mutation-induced activation of the luteinizing hormone receptor", J MOL BIOL, 296(5), 2000, pp. 1333-1351
12. Wilcox, RE; Huang, WH; Brusniak, MYK; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA
    CoMFA-based prediction of agonist affinities at recombinant wild type versus serine to alanine point mutated D2 dopamine receptors
    JOURNAL OF MEDICINAL CHEMISTRY
    
    R.E. Wilcox et al., "CoMFA-based prediction of agonist affinities at recombinant wild type versus serine to alanine point mutated D2 dopamine receptors", J MED CHEM, 43(16), 2000, pp. 3005-3019
13. Koch, SE; Bodi, I; Schwartz, A; Varadi, G
    Architecture of Ca2+ channel pore-lining segments revealed by covalent modification of substituted cysteines
    JOURNAL OF BIOLOGICAL CHEMISTRY
    
    S.E. Koch et al., "Architecture of Ca2+ channel pore-lining segments revealed by covalent modification of substituted cysteines", J BIOL CHEM, 275(44), 2000, pp. 34493-34500
14. Dube, P; DeCostanzo, A; Konopka, JB
    Interaction between transmembrane domains five and six of the alpha-factorreceptor
    JOURNAL OF BIOLOGICAL CHEMISTRY
    
    P. Dube et al., "Interaction between transmembrane domains five and six of the alpha-factorreceptor", J BIOL CHEM, 275(34), 2000, pp. 26492-26499
15. Kaplan, RS; Mayor, JA; Brauer, D; Kotaria, R; Walters, DE; Dean, AM
    The yeast mitochondrial citrate transport protein - Probing the secondary structure of transmembrane domain IV and identification of residues that likely comprise a portion of the citrate translocation pathway
    JOURNAL OF BIOLOGICAL CHEMISTRY
    
    R.S. Kaplan et al., "The yeast mitochondrial citrate transport protein - Probing the secondary structure of transmembrane domain IV and identification of residues that likely comprise a portion of the citrate translocation pathway", J BIOL CHEM, 275(16), 2000, pp. 12009-12016
16. Schetz, JA; Sibley, DR
    Tandem sulfur-containing amino acids are epicritical determinants of dopamine D-2 receptor pharmacology
    EUROPEAN JOURNAL OF PHARMACOLOGY
    
    J.A. Schetz e D.R. Sibley, "Tandem sulfur-containing amino acids are epicritical determinants of dopamine D-2 receptor pharmacology", EUR J PHARM, 388(2), 2000, pp. R5-R7
17. Reggio, PH
    Ligand-ligand and ligand-receptor approaches to modeling the cannabinoid CB1 and CB2 receptors: Achievements and challenges
    CURRENT MEDICINAL CHEMISTRY
    
    P.H. Reggio, "Ligand-ligand and ligand-receptor approaches to modeling the cannabinoid CB1 and CB2 receptors: Achievements and challenges", CURR MED CH, 6(8), 1999, pp. 665-683
18. Simpson, MM; Ballesteros, JA; Chiappa, V; Chen, JY; Suehiro, M; Hartman, DS; Godel, T; Snyder, LA; Sakmar, TP; Javitch, JA
    Dopamine D4/D2 receptor selectivity is determined by a divergent aromatic microdomain contained within the second, third, and seventh membrane-spanning segments
    MOLECULAR PHARMACOLOGY
    
    M.M. Simpson et al., "Dopamine D4/D2 receptor selectivity is determined by a divergent aromatic microdomain contained within the second, third, and seventh membrane-spanning segments", MOLEC PHARM, 56(6), 1999, pp. 1116-1126
19. Song, ZH; Slowey, CA; Hurst, DP; Reggio, PH
    The difference between the CB1 and CB2 cannabinoid receptors at position 5.46 is crucial for the selectivity of WIN55212-2 for CB2
    MOLECULAR PHARMACOLOGY
    
    Z.H. Song et al., "The difference between the CB1 and CB2 cannabinoid receptors at position 5.46 is crucial for the selectivity of WIN55212-2 for CB2", MOLEC PHARM, 56(4), 1999, pp. 834-840
20. Rasmussen, SGF; Jensen, AD; Liapakis, G; Ghanouni, P; Javitch, JA; Gether, U
    Mutation of a highly conserved aspartic acid in the beta(2) adrenergic receptor: Constitutive activation, structural instability, and conformational rearrangement of transmembrane segment 6
    MOLECULAR PHARMACOLOGY
    
    S.G.F. Rasmussen et al., "Mutation of a highly conserved aspartic acid in the beta(2) adrenergic receptor: Constitutive activation, structural instability, and conformational rearrangement of transmembrane segment 6", MOLEC PHARM, 56(1), 1999, pp. 175-184
21. Marjamaki, A; Frang, H; Pihlavisto, M; Hoffren, AM; Salminen, T; Johnson, MS; Kallio, J; Javitch, JA; Scheinin, M
    Chloroethylclonidine and 2-aminoethyl methanethiosulfonate recognize two different conformations of the human alpha(2A)-adrenergic receptor
    JOURNAL OF BIOLOGICAL CHEMISTRY
    
    A. Marjamaki et al., "Chloroethylclonidine and 2-aminoethyl methanethiosulfonate recognize two different conformations of the human alpha(2A)-adrenergic receptor", J BIOL CHEM, 274(31), 1999, pp. 21867-21872
22. Chen, SH; Xu, M; Lin, F; Lee, D; Riek, P; Graham, RM
    Phe(310) in transmembrane VI of the alpha(1B)-adrenergic receptor is a keyswitch residue involved in activation and catecholamine ring aromatic bonding
    JOURNAL OF BIOLOGICAL CHEMISTRY
    
    S.H. Chen et al., "Phe(310) in transmembrane VI of the alpha(1B)-adrenergic receptor is a keyswitch residue involved in activation and catecholamine ring aromatic bonding", J BIOL CHEM, 274(23), 1999, pp. 16320-16330
23. Williams, DB; Akabas, MH
    gamma-aminobutyric acid increases the water accessibility of M3 membrane-spanning segment residues in gamma-aminobutyric acid type A receptors
    BIOPHYSICAL JOURNAL
    
    D.B. Williams e M.H. Akabas, "gamma-aminobutyric acid increases the water accessibility of M3 membrane-spanning segment residues in gamma-aminobutyric acid type A receptors", BIOPHYS J, 77(5), 1999, pp. 2563-2574
24. VAYRO S; LO B; SILVERMAN M
    FUNCTIONAL-STUDIES OF THE RABBIT INTESTINAL NA+ GLUCOSE CARRIER (SGLT1) EXPRESSED IN COS-7 CELLS - EVALUATION OF THE MUTANT A166C INDICATESTHIS REGION IS IMPORTANT FOR NA+-ACTIVATION OF THE CARRIER/
    Biochemical journal
    
    S. Vayro et al., "FUNCTIONAL-STUDIES OF THE RABBIT INTESTINAL NA+ GLUCOSE CARRIER (SGLT1) EXPRESSED IN COS-7 CELLS - EVALUATION OF THE MUTANT A166C INDICATESTHIS REGION IS IMPORTANT FOR NA+-ACTIVATION OF THE CARRIER/", Biochemical journal, 332, 1998, pp. 119-125
25. LO B; SILVERMAN M
    REPLACEMENT OF ALA-166 WITH CYSTEINE IN THE HIGH-AFFINITY RABBIT SODIUM GLUCOSE TRANSPORTER ALTERS TRANSPORT KINETICS AND ALLOWS METHANETHIOSULFONATE ETHYLAMINE TO INHIBIT TRANSPORTER FUNCTION/
    The Journal of biological chemistry
    
    B. Lo e M. Silverman, "REPLACEMENT OF ALA-166 WITH CYSTEINE IN THE HIGH-AFFINITY RABBIT SODIUM GLUCOSE TRANSPORTER ALTERS TRANSPORT KINETICS AND ALLOWS METHANETHIOSULFONATE ETHYLAMINE TO INHIBIT TRANSPORTER FUNCTION/", The Journal of biological chemistry, 273(2), 1998, pp. 903-909
26. KONVICKA K; GUARNIERI F; BALLESTEROS JA; WEINSTEIN H
    A PROPOSED STRUCTURE FOR TRANSMEMBRANE SEGMENT-7 OF G-PROTEIN-COUPLEDRECEPTORS INCORPORATING AN ASN-PRO ASP-PRO MOTIF/
    Biophysical journal
    
    K. Konvicka et al., "A PROPOSED STRUCTURE FOR TRANSMEMBRANE SEGMENT-7 OF G-PROTEIN-COUPLEDRECEPTORS INCORPORATING AN ASN-PRO ASP-PRO MOTIF/", Biophysical journal, 75(2), 1998, pp. 601-611
27. HAN M; GROESBEEK M; SAKMAR TP; SMITH SO
    THE C9 METHYL-GROUP OF RETINAL INTERACTS WITH GLYCINE-121 IN RHODOPSIN
    Proceedings of the National Academy of Sciences of the United Statesof America
    
    M. Han et al., "THE C9 METHYL-GROUP OF RETINAL INTERACTS WITH GLYCINE-121 IN RHODOPSIN", Proceedings of the National Academy of Sciences of the United Statesof America, 94(25), 1997, pp. 13442-13447
28. BALDWIN JM; SCHERTLER GFX; UNGER VM
    AN ALPHA-CARBON TEMPLATE FOR THE TRANSMEMBRANE HELICES IN THE RHODOPSIN FAMILY OF G-PROTEIN-COUPLED RECEPTORS
    Journal of Molecular Biology
    
    J.M. Baldwin et al., "AN ALPHA-CARBON TEMPLATE FOR THE TRANSMEMBRANE HELICES IN THE RHODOPSIN FAMILY OF G-PROTEIN-COUPLED RECEPTORS", Journal of Molecular Biology, 272(1), 1997, pp. 144-164
29. GOULDSON PR; SNELL CR; REYNOLDS CA
    A NEW APPROACH TO DOCKING IN THE BETA(2)-ADRENERGIC RECEPTOR THAT EXPLOITS THE DOMAIN-STRUCTURE OF G-PROTEIN-COUPLED RECEPTORS
    Journal of medicinal chemistry
    
    P.R. Gouldson et al., "A NEW APPROACH TO DOCKING IN THE BETA(2)-ADRENERGIC RECEPTOR THAT EXPLOITS THE DOMAIN-STRUCTURE OF G-PROTEIN-COUPLED RECEPTORS", Journal of medicinal chemistry, 40(24), 1997, pp. 3871-3886
30. BENNETT ER; KANNER BI
    THE MEMBRANE TOPOLOGY OF GAT-1, A (NA-)-COUPLED GAMMA-AMINOBUTYRIC-ACID TRANSPORTER FROM RAT-BRAIN(+CL)
    The Journal of biological chemistry
    
    E.R. Bennett e B.I. Kanner, "THE MEMBRANE TOPOLOGY OF GAT-1, A (NA-)-COUPLED GAMMA-AMINOBUTYRIC-ACID TRANSPORTER FROM RAT-BRAIN(+CL)", The Journal of biological chemistry, 272(2), 1997, pp. 1203-1210
31. CHEN JG; LIUCHEN S; RUDNICK G
    EXTERNAL CYSTEINE RESIDUES IN THE SEROTONIN TRANSPORTER
    Biochemistry
    
    J.G. Chen et al., "EXTERNAL CYSTEINE RESIDUES IN THE SEROTONIN TRANSPORTER", Biochemistry, 36(6), 1997, pp. 1479-1486
32. HAN M; LIN SW; SMITH SO; SAKMAR TP
    THE EFFECTS OF AMINO-ACID REPLACEMENTS OF GLYCINE-121 ON TRANSMEMBRANE HELIX-3 OF RHODOPSIN
    The Journal of biological chemistry
    
    M. Han et al., "THE EFFECTS OF AMINO-ACID REPLACEMENTS OF GLYCINE-121 ON TRANSMEMBRANE HELIX-3 OF RHODOPSIN", The Journal of biological chemistry, 271(50), 1996, pp. 32330-32336
33. HAN M; LIN SW; MINKOVA M; SMITH SO; SAKMAR TP
    FUNCTIONAL INTERACTION OF TRANSMEMBRANE HELICE-3 AND HELICE-6 IN RHODOPSIN - REPLACEMENT OF PHENYLALANINE-261 BY ALANINE CAUSES REVERSION OF PHENOTYPE OF A GLYCINE-121 REPLACEMENT MUTANT
    The Journal of biological chemistry
    
    M. Han et al., "FUNCTIONAL INTERACTION OF TRANSMEMBRANE HELICE-3 AND HELICE-6 IN RHODOPSIN - REPLACEMENT OF PHENYLALANINE-261 BY ALANINE CAUSES REVERSION OF PHENOTYPE OF A GLYCINE-121 REPLACEMENT MUTANT", The Journal of biological chemistry, 271(50), 1996, pp. 32337-32342