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Use of the substituted cysteine accessibility method to study the structure and function of G protein-coupled receptors
G PROTEIN PATHWAYS, PT A, RECEPTORS
Three-dimensional representations of G protein-coupled receptor structuresand mechanisms
G PROTEIN PATHWAYS, PT A, RECEPTORS
D-1 dopamine receptors
INTERNATIONAL REVIEW OF NEUROBIOLOGY, VOL 48
Reaction of oxidized dopamine with endogenous cysteine residues in the human dopamine transporter
JOURNAL OF NEUROCHEMISTRY
3-aryl[1,2,4]triazino[4,3-alpha]benzimidazol-4(10H)-ones: A new class of selective A(1) adenosine receptor antagonists
JOURNAL OF MEDICINAL CHEMISTRY
Stepwise modulation of neurokinin-3 and neurokinin-2 receptor affinity andselectivity in quinoline tachykinin receptor antagonists
JOURNAL OF MEDICINAL CHEMISTRY
The TXP motif in the second transmembrane helix of CCR5 - A structural determinant of chemokine-induced activation
JOURNAL OF BIOLOGICAL CHEMISTRY
Dopamine receptors and locomotor responses: Molecular aspects
ANNALS OF NEUROLOGY
CCK-B/gastrin receptor transmembrane domain mutations selectively alter synthetic agonist efficacy without affecting the activity of endogenous peptides
MOLECULAR PHARMACOLOGY
Nonconserved residues in the second transmembrane-spanning domain of the D-4 dopamine receptor are molecular determinants of D-4-selective pharmacology
MOLECULAR PHARMACOLOGY
Theoretical study on mutation-induced activation of the luteinizing hormone receptor
JOURNAL OF MOLECULAR BIOLOGY
CoMFA-based prediction of agonist affinities at recombinant wild type versus serine to alanine point mutated D2 dopamine receptors
JOURNAL OF MEDICINAL CHEMISTRY
Architecture of Ca2+ channel pore-lining segments revealed by covalent modification of substituted cysteines
JOURNAL OF BIOLOGICAL CHEMISTRY
Interaction between transmembrane domains five and six of the alpha-factorreceptor
JOURNAL OF BIOLOGICAL CHEMISTRY
The yeast mitochondrial citrate transport protein - Probing the secondary structure of transmembrane domain IV and identification of residues that likely comprise a portion of the citrate translocation pathway
JOURNAL OF BIOLOGICAL CHEMISTRY
Tandem sulfur-containing amino acids are epicritical determinants of dopamine D-2 receptor pharmacology
EUROPEAN JOURNAL OF PHARMACOLOGY
Ligand-ligand and ligand-receptor approaches to modeling the cannabinoid CB1 and CB2 receptors: Achievements and challenges
CURRENT MEDICINAL CHEMISTRY
Dopamine D4/D2 receptor selectivity is determined by a divergent aromatic microdomain contained within the second, third, and seventh membrane-spanning segments
MOLECULAR PHARMACOLOGY
The difference between the CB1 and CB2 cannabinoid receptors at position 5.46 is crucial for the selectivity of WIN55212-2 for CB2
MOLECULAR PHARMACOLOGY
Mutation of a highly conserved aspartic acid in the beta(2) adrenergic receptor: Constitutive activation, structural instability, and conformational rearrangement of transmembrane segment 6
MOLECULAR PHARMACOLOGY
Chloroethylclonidine and 2-aminoethyl methanethiosulfonate recognize two different conformations of the human alpha(2A)-adrenergic receptor
JOURNAL OF BIOLOGICAL CHEMISTRY
Phe(310) in transmembrane VI of the alpha(1B)-adrenergic receptor is a keyswitch residue involved in activation and catecholamine ring aromatic bonding
JOURNAL OF BIOLOGICAL CHEMISTRY
gamma-aminobutyric acid increases the water accessibility of M3 membrane-spanning segment residues in gamma-aminobutyric acid type A receptors
BIOPHYSICAL JOURNAL
FUNCTIONAL-STUDIES OF THE RABBIT INTESTINAL NA+ GLUCOSE CARRIER (SGLT1) EXPRESSED IN COS-7 CELLS - EVALUATION OF THE MUTANT A166C INDICATESTHIS REGION IS IMPORTANT FOR NA+-ACTIVATION OF THE CARRIER/
Biochemical journal
REPLACEMENT OF ALA-166 WITH CYSTEINE IN THE HIGH-AFFINITY RABBIT SODIUM GLUCOSE TRANSPORTER ALTERS TRANSPORT KINETICS AND ALLOWS METHANETHIOSULFONATE ETHYLAMINE TO INHIBIT TRANSPORTER FUNCTION/
The Journal of biological chemistry
A PROPOSED STRUCTURE FOR TRANSMEMBRANE SEGMENT-7 OF G-PROTEIN-COUPLEDRECEPTORS INCORPORATING AN ASN-PRO ASP-PRO MOTIF/
Biophysical journal
THE C9 METHYL-GROUP OF RETINAL INTERACTS WITH GLYCINE-121 IN RHODOPSIN
Proceedings of the National Academy of Sciences of the United Statesof America
AN ALPHA-CARBON TEMPLATE FOR THE TRANSMEMBRANE HELICES IN THE RHODOPSIN FAMILY OF G-PROTEIN-COUPLED RECEPTORS
Journal of Molecular Biology
A NEW APPROACH TO DOCKING IN THE BETA(2)-ADRENERGIC RECEPTOR THAT EXPLOITS THE DOMAIN-STRUCTURE OF G-PROTEIN-COUPLED RECEPTORS
Journal of medicinal chemistry
THE MEMBRANE TOPOLOGY OF GAT-1, A (NA-)-COUPLED GAMMA-AMINOBUTYRIC-ACID TRANSPORTER FROM RAT-BRAIN(+CL)
The Journal of biological chemistry
EXTERNAL CYSTEINE RESIDUES IN THE SEROTONIN TRANSPORTER
Biochemistry
THE EFFECTS OF AMINO-ACID REPLACEMENTS OF GLYCINE-121 ON TRANSMEMBRANE HELIX-3 OF RHODOPSIN
The Journal of biological chemistry
FUNCTIONAL INTERACTION OF TRANSMEMBRANE HELICE-3 AND HELICE-6 IN RHODOPSIN - REPLACEMENT OF PHENYLALANINE-261 BY ALANINE CAUSES REVERSION OF PHENOTYPE OF A GLYCINE-121 REPLACEMENT MUTANT
The Journal of biological chemistry