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Direct measurement of pH profiles in immobilized enzyme carriers during kinetically controlled synthesis using CLSM
BIOTECHNOLOGY PROGRESS
Biotransformations catalyzed by multimeric enzymes: Stabilization of tetrameric ampicillin acylase permits the optimization of ampicillin synthesis under dissociation conditions
BIOMACROMOLECULES
Efficiency of cephalosporin complexation with aromatic compounds
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2
Complexants for the clathration mediated synthesis of the antibiotic cephradine
GREEN CHEMISTRY
Theoretical study of amine-assisted aminolysis of penicillins - The kinetic role of the carboxylate group
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Kinetically controlled synthesis of ampicillin with immobilized penicillinacylase in the presence of organic cosolvents
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
Cross-linked aggregates of penicillin acylase: robust catalysts for the synthesis of beta-lactam antibiotics
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
The role of a beta-proton transfer donor in the degradation of benzylpenicillin
JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL
Theoretical study of nitrile hydrolysis reaction on Zn(II) ion exchanged zeolites
JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL
Biochemical characterization of chromosomal cephalosporinases from isolates belonging to the Acinetobacter baumannii complex
CLINICAL MICROBIOLOGY AND INFECTION
Nasopharyngeal carriage of penicillin-resistant, macrolide-resistant and multiply-resistant Streptococcus pneumoniae in day-care centers in Sofia, Bulgaria
CLINICAL MICROBIOLOGY AND INFECTION
Renal transport of antibiotics and nephrotoxicity: a review
JOURNAL OF CHEMOTHERAPY
An observational study on the epidemiology of respiratory tract bacterial pathogens and their susceptibility to four injectable beta-lactam antibiotics: Piperacillin, piperacillin/tazobactam, ceftazidime and ceftriaxone
JOURNAL OF CHEMOTHERAPY
Liquid chromatographic determination/identification of residual penicillinG in food-producing animal tissues
JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES
Delayed hypersensitivity to cefazolin: report on a case involving lymphocyte transformation studies with different cephalosporins
ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY
Ocular pharmacokinetics of cephalosporins using microdialysis
JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS
Emergence of vancomycin-resistant enterococci
EMERGING INFECTIOUS DISEASES
Serum concentrations of cefuroxime after continuous infusion in coronary bypass graft patients
ANNALS OF PHARMACOTHERAPY
Expression of the myc/His-tagged human peptide transporter hPEPT1 in yeastfor protein purification and functional analysis
PROTEIN EXPRESSION AND PURIFICATION
Significance of substrate hydrophobicity for recognition by an oligopeptide transporter (PEPT1)
BIOCONJUGATE CHEMISTRY
Syntheses and hydrolysis of basic and dibasic ampicillin esters tailored for intracellular accumulation
BIOORGANIC & MEDICINAL CHEMISTRY
Identification of residues critical for metallo-beta-lactamase function bycodon randomization and selection
PROTEIN SCIENCE
Highly sensitive enzyme immunoassays for the detection of beta-lactam antibiotics
FOOD AND AGRICULTURAL IMMUNOLOGY
Rapid and sensitive quantitation of antibiotics in fermentations by electrospray mass spectrometry
RAPID COMMUNICATIONS IN MASS SPECTROMETRY
Involvement of N-acetylmuramyl-L-alanine amidases in cell separation and antibiotic-induced autolysis of Escherichia coli
MOLECULAR MICROBIOLOGY
MspA provides the main hydrophilic pathway through the cell wall of Mycobacterium smegmatis
MOLECULAR MICROBIOLOGY
Predicting when precipitation-driven synthesis is feasible: Application tobiocatalysis
CHEMISTRY-A EUROPEAN JOURNAL
Determination of benzylpenicillin, oxacillin, cloxacillin, and dicloxacillin in cows' milk by ion-pair high-performance liquid chromatography after precolumn derivatization
FRESENIUS JOURNAL OF ANALYTICAL CHEMISTRY
Efflux pumps: Their role in antibacterial drug discovery
CURRENT MEDICINAL CHEMISTRY
Mechanisms other than penicillin-binding protein-2 alterations may contribute to moderate penicillin resistance in Neisseria meningitidis
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
Antimicrobial resistance and serotype distribution of Streptococcus pneumoniae isolates from Crete, Greece
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
The in vitro activity of sulbactam combined with third generation cephalosporins against third generation cephalosporin-resistant bacteria
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
Systemic antibiotic agents
DERMATOLOGIC CLINICS
Penetration of cefaclor into the interstitial space fluid of skeletal muscle and lung tissue in rats
PHARMACEUTICAL RESEARCH
Antibiotic administration in Gram-negative bacilli infections.
MEDECINE ET MALADIES INFECTIEUSES
The structural aspects of carbapenem antibiotics
HETEROCYCLES
Oral absorption of cephalosporins is quantitatively predicted from in vitro uptake into intestinal brush border membrane vesicles
INTERNATIONAL JOURNAL OF PHARMACEUTICS
Electrochemical study of amoxicillin antibiotic across liquid-liquid interface
BOLETIN DE LA SOCIEDAD CHILENA DE QUIMICA
Upregulation of H+-peptide cotransporter PEPT2 in rat remnant kidney
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
Allergy to betalactams in children: diagnosis of non-immediate hypersensitivity by means of skin tests and oral challenge.
REVUE FRANCAISE D ALLERGOLOGIE ET D IMMUNOLOGIE CLINIQUE
4-Oxoazetidine-2-carbaldehydes as useful building blocks in stereocontrolled synthesis
CHEMICAL SOCIETY REVIEWS
The problem with cephalosporins
Journal of antimicrobial chemotherapy
Detection of methicillin/oxacillin resistance in staphylococci
Journal of antimicrobial chemotherapy
In vivo efficacy of continuous infusion versus intermittent dosing of ceftazidime alone or in combination with amikacin relative to human kinetic profiles in a Pseudomonas aeruginosa rabbit endocarditis model
Journal of antimicrobial chemotherapy
Approaching the physiological functions of penicillin-binding proteins in Escherichia coli
BIOCHIMIE
Use of ampicillin/sulbactam and sultamicillin in pediatric infections: a re-evaluation
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
What in vitro models of infection can and cannot do
PHARMACOTHERAPY
What do we really know about antibiotic pharmacodynamics?
PHARMACOTHERAPY
Pharmacodynamics of antiinfective therapy: Taking what we know to the patient's bedside
PHARMACOTHERAPY
Outpatient parenteral antimicrobial therapy (OPAT) for the treatment of osteomyelitis: evaluation of efficacy, tolerance and cost
JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS
Bioequivalence evaluation of two brands of cefaclor 500 mg capsules: quantification of cefaclor using solid phase extraction technique
JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS
Synthesis and in vitro antibacterial activity of cephalosporins with a pyridinium substituent carrying an isoxazole moiety at the C-3 position
ARCHIVES OF PHARMACAL RESEARCH
Intestinal peptide transport: ex vivo uptake studies and localization of peptide carrier PEPT1
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
Epidermal growth factor inhibits glycylsarcosine transport and hPepT1 expression in a human intestinal cell line
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
Intestinal drug efflux: formulation and food effects
ADVANCED DRUG DELIVERY REVIEWS
Semi-empirical quantum chemical study on structure-activity relationship in monocyclic-beta-lactam antibiotics
JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM
Organotypic hippocampal cultures - A model of brain tissue damage in Streptococcus pneumoniae meningitis
JOURNAL OF NEUROIMMUNOLOGY
Bioavailability and disposition of sodium and procaine penicillin G (benzylpenicillin) administered orally with milk to calves
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS
Cholangiopathy after short-term administration of piperacillin and imipenem/cilastatin
LIVER
Cysteinyl-leukotriene release test (CAST) in the diagnosis of immediate drug reactions
ALLERGY
Occupational allergic contact urticaria from amoxicillin
CONTACT DERMATITIS
Is this patient allergic to penicillin? An evidence-based analysis of the likelihood of penicillin allergy
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
Drug metabolism, danger signals, and drug-induced hypersensitivity
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
Mechanism of intestinal absorption and renal reabsorption of an orally active ACE inhibitor: Uptake and transport of fosinopril in cell cultures
DRUG METABOLISM AND DISPOSITION
Characterization of tubular functional capacity in humans using para-aminohippurate and famotidine
KIDNEY INTERNATIONAL
Risk factors for emergence of resistance to broad-spectrum cephalosporins among Enterobacter spp.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Stability and compatibility of ceftazidime administered by continuous infusion to intensive care patients
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Pseudomonas aeruginosa reveals high intrinsic resistance to penem antibiotics: Penem resistance mechanisms and their interplay
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Activity of LY333328 in experimental meningitis caused by a Streptococcus pneumoniae strain susceptible to penicillin
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Pharmacokinetic-pharmacodynamic modeling of the electroencephalogram effect of imipenem in healthy rats
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Penicillin-binding protein 5 and expression of ampicillin resistance in Enterococcus faecium
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Guest commentary - Autolysis control hypotheses for tolerance to wall antibiotics
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Correlation between in vitro and in vivo activities of GM 237354, a new sordarin derivative, against Candida albicans in an in vitro pharmacokinetic-pharmacodynamic model and influence of protein binding
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Identification and characterization of inhibitors of multidrug resistance efflux pumps in Pseudomonas aeruginosa: Novel agents for combination therapy
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
In vitro activity of trovafloxacin against Bacteroides fragilis in mixed culture with either Escherichia coli or a vancomycin-resistant strain of Enterococcus faecium determined by an anaerobic time-kill technique
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
New orally active penem antibiotic: Farom
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN
High rates of multiple antibiotic resistance in Streptococcus pneumoniae from healthy children living in isolated rural communities: Association withcephalosporin use and intrafamilial transmission
PEDIATRICS
Developmental expression of PEPT1 and PEPT2 in rat small intestine, colon,and kidney
PEDIATRIC RESEARCH
Cephalosporin allergy
NEW ENGLAND JOURNAL OF MEDICINE
Molecular and physiological evidence for multifunctionality of carnitine/organic cation transporter OCTN2
MOLECULAR PHARMACOLOGY
The effects of subminimal inhibitory concentrations of beta-lactam antibiotics against Clostridium perfringens
MICROBIOS
Selection of antibiotic-resistant bacteria: microbiological and pharmacological factors
MEDICINA CLINICA
Current in vitro sensitivity of the most frequent bacterial respiratory pathogens: clinical implications
MEDICINA CLINICA
Antimicrobial selection in the penicillin-allergic patient
DRUGS OF TODAY
Bidirectional electrogenic transport of peptides by the proton-coupled carrier PEPT1 in Xenopus laevis oocytes: its asymmetry and symmetry
JOURNAL OF PHYSIOLOGY-LONDON
Evaluation of a single-pass intestinal-perfusion method in rat for the prediction of absorption in man
JOURNAL OF PHARMACY AND PHARMACOLOGY
Correlation between epithelial cell permeability of cephalexin and expression of intestinal oligopeptide transporter
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
Flavonoids with epidermal growth factor-receptor tyrosine kinase inhibitory activity stimulate PEPT1-mediated cefixime uptake into human intestinal epithelial cells
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
Recognition and transport characteristics of nonpeptidic compounds by basolateral peptide transporter in Caco-2 cells
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
Transporters involved in the elimination of drugs in the kidney: Organic anion transporters and organic cation transporters
JOURNAL OF PHARMACEUTICAL SCIENCES
Expression of a cloned ovine gastrointestinal peptide transporter (oPepT1)in Xenopus oocytes induces uptake of oligopeptides in vitro
JOURNAL OF NUTRITION
Crystal structure and site-directed mutagenesis studies of N-carbamoyl-D-amino-acid amidohydrolase from Agrobacterium radiobacter reveals a homotetramer and insight into a catalytic cleft
JOURNAL OF MOLECULAR BIOLOGY
Alterations to penicillin-binding proteins 1A, 2B and 2X amongst penicillin-resistant clinical isolates of Streptococcus pneumoniae serotype 23F fromthe nasopharyngeal flora of children
JOURNAL OF MEDICAL MICROBIOLOGY
PepT1-mediated epithelial transport of dipeptides and cephalexin is enhanced by luminal leptin in the small intestine
JOURNAL OF CLINICAL INVESTIGATION
Crystal structure of PBP2x from a highly penicillin-resistant Streptococcus pneumoniae clinical isolate - A mosaic framework containing 83 mutations
JOURNAL OF BIOLOGICAL CHEMISTRY
Contributions of PBP 5 and DD-carboxypeptidase penicillin binding proteinsto maintenance of cell shape in Escherichia coli
JOURNAL OF BACTERIOLOGY
Differential responses of Escherichia coli cells expressing cytoplasmic domain mutants of penicillin-binding protein 1b after impairment of penicillin-binding proteins 1a and 3
JOURNAL OF BACTERIOLOGY
Generation of class-selective monoclonal antibodies against the penicillingroup
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Solid-phase extraction followed by liquid chromatography-mass spectrometryfor trace determination of beta-lactam antibiotics in bovine milk
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Modulation by cyclic AMP and phorbol myristate acetate of cephaloridine-induced injury in rat renal cortical slices
JAPANESE JOURNAL OF PHARMACOLOGY