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    1. Pappa-Louisi, A; Papageorgiou, A; Zitrou, A; Sotiropoulos, S; Georgarakis, E; Zougrou, F
      Study on the electrochemical detection of the macrolide antibiotics clarithromycin and roxithromycin in reversed-phase high-performance liquid chromatography

      JOURNAL OF CHROMATOGRAPHY B
    2. Perez-Casas, C; Herranz, E; Ford, N
      Pricing of drugs and donations: options for sustainable equity pricing

      TROPICAL MEDICINE & INTERNATIONAL HEALTH
    3. Pascual, A; Ballesta, S; Garcia, I; Perea, EJ
      Uptake and intracellular activity of ketolide HMR 3647 in human phagocyticand non-phagocytic cells

      CLINICAL MICROBIOLOGY AND INFECTION
    4. Christenson, JC; Fischer, PR; Hale, DC; Derrick, D
      Pediatric travel consultation in an integrated clinic

      JOURNAL OF TRAVEL MEDICINE
    5. Skerk, V; Schonwald, S; Strapac, Z; Beus, A; Francetic, I; Krhen, I; Lesko, V; Vukovic, J
      Duration of clinical symptoms in female patients with acute urethral syndrome caused by Chlamydia trachomatis treated with azithromycin or doxycycline

      JOURNAL OF CHEMOTHERAPY
    6. Labro, MT; Abdelghaffar, H
      Immunomodulation by macrolide antibiotics

      JOURNAL OF CHEMOTHERAPY
    7. Palavecino, EL
      The crisis of resistant pathogens in respiratory tract infections - Use ofpharmacodynamic principles

      AMERICAN JOURNAL OF MANAGED CARE
    8. Preston, SL; Drusano, GL
      Telithromycin - A once-daily, broad-spectrum ketolide for treatment of various respiratory infections

      FORMULARY
    9. McCarty, JM; Pierce, PF
      Five days of cefprozil versus 10 days of clarithromycin in the treatment of an acute exacerbation of chronic bronchitis

      ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY
    10. Chahine, C; Moukhachen, O; Chedid, M; Araj, GF; Sharara, AI
      Ultrashort regimen of lansoprazole-amoxicillin-azithromycin for eradicating Helicobacter pylori

      AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY
    11. Klugman, KP
      Antibiotic selection of multiply resistant pneumococci

      CLINICAL INFECTIOUS DISEASES
    12. Gimenez-Sanchez, F; Butler, JC; Jernigan, DB; Strausbaugh, LJ; Slemp, CC; Perilla, MJ; Dowell, SF
      Treating cardiovascular disease with antimicrobial agents: A survey of knowledge, attitudes, and practices among physicians in the United States

      CLINICAL INFECTIOUS DISEASES
    13. Simdon, J; Watters, D; Bartlett, S; Connick, E
      Ototoxicity may be associated with protease inhibitor therapy - Reply

      CLINICAL INFECTIOUS DISEASES
    14. Young, LS; Bermudez, LE
      Perspective on animal models: Chronic intracellular infections

      CLINICAL INFECTIOUS DISEASES
    15. Dworkin, MS; Ward, JW; Hanson, DL; Jones, JL; Kaplan, JE
      Pneumococcal disease among human immunodeficiency virus-infected persons: Incidence, risk factors, and impact of vaccination

      CLINICAL INFECTIOUS DISEASES
    16. Tan, JS; File, TM; DiPersio, JR; DiPersio, LP; Hamor, R; Saravolatz, LD; Stout, JE
      Persistently positive culture results in a patient with community-acquiredpneumonia due to Legionella pneumophila

      CLINICAL INFECTIOUS DISEASES
    17. Murphy, EL; Assmann, SF; Collier, AC; Flanigan, TP; Kumar, PN; Wallach, FR; Krubel, S
      Determinants of antimicrobial prophylaxis use and treatment for wasting among patients with advanced human immunodeficiency virus disease in the United States, 1995-1998

      CLINICAL INFECTIOUS DISEASES
    18. Gerber, MA; Tanz, RR
      New approaches to the treatment of group A streptococcal pharyngitis

      CURRENT OPINION IN PEDIATRICS
    19. Conrad, DA
      Treatment of cat-scratch disease

      CURRENT OPINION IN PEDIATRICS
    20. Moriarty, HJ
      Mathematical modelling: what it can offer to sexual health

      VENEREOLOGY-THE INTERDISCIPLINARY INTERNATIONAL JOURNAL OF SEXUAL HEALTH
    21. Mabey, D; Fraser-Hurt, N
      Extracts from "Clinical Evidence" - Trachoma

      BRITISH MEDICAL JOURNAL
    22. Dale, AWS; Horner, PJ; Forster, GE; Daniels, D; Tomlinson, D; Brook, MG
      Management of Chlamydia trachomatis genital tract infection in Genitourinary Medicine clinics in the United Kingdom's North Thames Region 1999

      INTERNATIONAL JOURNAL OF STD & AIDS
    23. Goh, BT; Vader, PCV
      European guideline for the management of syphilis

      INTERNATIONAL JOURNAL OF STD & AIDS
    24. File, TM
      Community-acquired pneumonia: new guidelines for management

      CURRENT OPINION IN INFECTIOUS DISEASES
    25. Andes, D
      Pharmacokinetic and pharmacodynamic properties of antimicrobials in the therapy of respiratory tract infections

      CURRENT OPINION IN INFECTIOUS DISEASES
    26. Hammerschlag, MR
      Mycoplasma pneumoniae infections

      CURRENT OPINION IN INFECTIOUS DISEASES
    27. Usary, J; Champney, WS
      Erythromycin inhibition of 50S ribosomal subunit formation in Escherichia coli cells

      MOLECULAR MICROBIOLOGY
    28. Maraha, B; den Heijer, M; Wullink, M; van der Zee, A; Bergmans, A; Verbakel, H; Kerver, M; Graafsma, S; Kranendonk, S; Peeters, M
      Detection of Chlamydia pneumoniae DNA in buffy-coat samples of patients with abdominal aortic aneurysm

      EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
    29. Bragina, EY; Gomberg, MA; Dmitriev, GA
      Electron microscopic evidence of persistent chlamydial infection followingtreatment

      JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
    30. Hand, WL; Hand, DL
      Characteristics and mechanisms of azithromycin accumulation and efflux in human polymorphonuclear leukocytes

      INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
    31. Treadway, G; Reisman, A
      Tolerability of 3-day, once-daily azithromycin suspension versus standard treatments for community-acquired paediatric infectious diseases

      INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
    32. Retsema, J; Fu, WC
      Macrolides: structures and microbial targets

      INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
    33. Amsden, GW
      Advanced-generation macrolides: tissue-directed antibiotics

      INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
    34. Van Bambeke, F; Tulkens, PM
      Macrolides: pharmacokinetics and pharmacodynamics

      INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
    35. Perea, E
      Clinical relevance of laboratory susceptibility data

      INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
    36. Dalhoff, K
      Worldwide guidelines for respiratory tract infections: community-acquired pneumonia

      INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
    37. Mulazimoglu, L
      Treatment of community-acquired pneumonia in hospitalised patients

      INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
    38. Rubinstein, E
      Comparative safety of the different macrolides

      INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
    39. Williams, JD
      Evaluation of the safety of macrolides

      INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
    40. Pechere, JC
      New perspectives on macrolide antibiotics

      INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
    41. Fera, MT; Giannone, M; Pallio, S; Tortora, A; Blandino, G; Carbone, M
      Antimicrobial activity and postantibiotic effect of flurithromycin againstHelicobacter pylori strains

      INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
    42. Anand, V; Gupta, S
      Antibiotic therapy in coronary heart disease - Where do we currently stand?

      CARDIOVASCULAR DRUGS AND THERAPY
    43. Gieffers, J; Solbach, W; Maass, M
      In vitro susceptibility and eradication of chlamydia pneumoniae cardiovascular strains from coronary artery endothelium and smooth muscle cells

      CARDIOVASCULAR DRUGS AND THERAPY
    44. Kent, JR; Almond, MK; Dhillon, S
      Azithromycin: An assessment of its pharmacokinetics and therapeutic potential in CAPD

      PERITONEAL DIALYSIS INTERNATIONAL
    45. Dagan, R; Hoberman, A; Johnson, C; Leibovitz, EL; Arguedas, A; Rose, FV; Wynne, BR; Jacobs, MR
      Bacteriologic and clinical efficacy of high dose amoxicillin/clavulanate in children with acute otitis media

      PEDIATRIC INFECTIOUS DISEASE JOURNAL
    46. Ngeh, J; Gupta, S
      Inflammation, infection and antimicrobial therapy in coronary heart disease - where do we currently stand?

      FUNDAMENTAL & CLINICAL PHARMACOLOGY
    47. Isefuku, S; Joyner, CJ; Simpson, AHRW
      Toxic effect of rifampicin on human osteoblast-like cells

      JOURNAL OF ORTHOPAEDIC RESEARCH
    48. Stewart, CE; Coleman, K; Mortensen, J
      Effect of extended pre-incubation with Chlamydia pneumoniae and extended incubation with antimicrobial on the minimum inhibitory concentrations (MICs) of five antimicrobials

      DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
    49. Murris-Espin, M; Mazieres, J; Heurtaux, W; Leophonte, P
      Dealing with acute bronchitis in adults without pre-existing respiratory pathology - the place of short treatment - comparison of costs.

      MEDECINE ET MALADIES INFECTIEUSES
    50. Cohen, R; Aberrane, S; Ovetchkine, P
      Antibiotics and pertussis.

      MEDECINE ET MALADIES INFECTIEUSES
    51. Heurtin, C; Desbordes, L; Travert, MF; Donnio, PY; Avril, JL
      Comparative bacterlostatic, and bactericidal activities of levofloxacin against clinical Pasteurella isolates

      PATHOLOGIE BIOLOGIE
    52. Rosandic, M
      Antibiotic-resistance patterns of Helicobacter pylori in Croatia: Cohort study

      CROATIAN MEDICAL JOURNAL
    53. Edelstein, PH; Shinzato, T; Edelstein, MAC
      BMS-284756 (T-381 1ME) a new fluoroquinolone: in vitro activity against Legionella, efficacy in a guinea pig model of L-pneumophila pneumonia and pharmacokinetics in guinea pigs

      Journal of antimicrobial chemotherapy
    54. Ulvatne, H; Karoliussen, S; Stiberg, T; Rekdal, O; Svendsen, JS
      Short antibacterial peptides and erythromycin act synergically against Escherichia coli

      Journal of antimicrobial chemotherapy
    55. Honeybourne, D; Banerjee, D; Andrews, J; Wise, R
      Concentrations of gatifloxacin in plasma and pulmonary compartments following a single 400 mg oral dose in patients undergoing fibre-optic bronchoscopy

      Journal of antimicrobial chemotherapy
    56. Martin, SJ; Garvin, GG; McBurney, CR; Sahloff, EG
      The activity of 14-hydroxy clarithromycin, alone and in combination with clarithromycin, against penicillin- and erythromycin-resistant Streptococcuspneumoniae

      Journal of antimicrobial chemotherapy
    57. Graybill, JR; Bocanegra, R
      Treatment alternatives for Mycobacterium kansasii

      Journal of antimicrobial chemotherapy
    58. Gurfinkel, EP
      Infection and atherosclerosis

      REVISTA ESPANOLA DE CARDIOLOGIA
    59. Kastner, U; Guggenbichler, JP
      Influence of macrolide antibiotics on promotion of resistance in the oral flora of children

      INFECTION
    60. Baumann, U; Fischer, JJ; Gudowius, P; Lingner, M; Herrmann, S; Tummler, B; von der Hardt, H
      Buccal adherence of Pseudomonas aeruginosa in patients with cystic fibrosis under long-term therapy with azithromycin

      INFECTION
    61. Jacobson, JM; Hafner, R; Remington, J; Farthing, C; Holden-Wiltse, J; Bosler, EM; Harris, C; Jayaweera, DT; Roque, C; Luft, BJ
      Dose-escalation, phase I/II study of azithromycin and pyrimethamine for the treatment of toxoplasmic encephalitis in AIDS

      AIDS
    62. Laurent, J; Megraud, F; Flejou, JF; Caekaert, A; Barthelemy, P
      A randomized comparison of four omeprazole-based triple therapy regimens for the eradication of Helicobacter pylori in patients with non-ulcer dyspepsia

      ALIMENTARY PHARMACOLOGY & THERAPEUTICS
    63. Abgueguen, P; Chennebault, JM; Achard, J; Cottin, J; Pichard, E
      Cat scratch disease. Clinical study of 26 patients. Place and importance of PCR.

      REVUE DE MEDECINE INTERNE
    64. Sorvillo, F; Beall, G; Turner, PA; Beer, VL; Kovacs, AA; Kerndt, PR
      Incidence and determinants of Pseudomonas aeruginosa infection among persons with HIV: Association with hospital exposure

      AMERICAN JOURNAL OF INFECTION CONTROL
    65. Tyteca, D; Van Der Smissen, P; Van Bambeke, F; Leys, K; Tulkens, PM; Courtoy, PJ; Mingeot-Leclercq, MP
      Azithromycin, a lysosomotropic antibiotic, impairs fluid-phase pinocytosisin cultured fibroblasts

      EUROPEAN JOURNAL OF CELL BIOLOGY
    66. De Diego, JI; Prim, MP; Alfonso, C; Sastre, N; Rabanal, I; Gavilan, J
      Comparison of amoxicillin and azithromycin in the prevention of recurrent acute otitis media

      INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
    67. Conti, CR
      Secondary prevention antibiotic treatment trials

      CLINICAL CARDIOLOGY
    68. Kays, MB; Denys, GA
      In vitro activity and pharmacodynamics of azithromycin and clarithromycin against Streptococcus pneumoniae based on serum and intrapulmonary pharmacokinetics

      CLINICAL THERAPEUTICS
    69. Gupta, S; Banfield, C; Kantesaria, B; Marino, M; Clement, R; Affrime, M; Batra, V
      Pharmacokinetic and safety profile of desloratadine and fexofenadine when coadministered with azithromycin: A randomized, placebo-controlled, parallel-group study

      CLINICAL THERAPEUTICS
    70. Dillon, JAR; Li, H; Sealy, J; Ruben, M; Prabhakar, P
      Antimicrobial susceptibility of Neisseria gonorrhoeae isolates from three Caribbean countries: Trinidad, Guyana, and St. Vincent

      SEXUALLY TRANSMITTED DISEASES
    71. Karrow, NA; McCay, JA; Brown, RD; Musgrove, DL; Germolec, DR; White, KL
      Evaluation of the immunomodulatory effects of the macrolide antibiotic, clarithromycin, in female B6C3F1 mice: A 28-day oral gavage study

      DRUG AND CHEMICAL TOXICOLOGY
    72. Samarendra, P; Kumari, S; Evans, SJ; Sacchi, TJ; Navarro, V
      QT prolongation associated with azithromycin/amiodarone combination

      PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
    73. Najib, NM; Idkaidek, N; Ghanem, IE; Admour, I; Alam, SM; Zaman, Q; Dham, R
      Bioequivalence assessment of Azomycin (R) (Julphar, UEA) as compared with Zithromax (R) (Pfizer, USA) - Two brands of azithromycin - In healthy humanvolunteers

      BIOPHARMACEUTICS & DRUG DISPOSITION
    74. Neumann, FJ; Kastrati, A; Miethke, T; Pogatsa-Murray, G; Mehilli, J; Valina, C; Jogethaei, N; da Costa, CP; Wagner, H; Schomig, A
      Treatment of Chlamydia pneumoniae infection with roxithromycin and effect on neointima proliferation after coronary stent placement (ISAR-3): a randomised, double-blind, placebo-controlled trial

      LANCET
    75. Milkovic-Kraus, S; Kanceljak-Macan, B
      Occupational airborne allergic contact dermatitis from azithromycin

      CONTACT DERMATITIS
    76. Hyde, TB; Gay, K; Stephens, DS; Vugia, DJ; Pass, M; Johnson, S; Barrett, NL; Schaffner, W; Cieslak, PR; Maupin, PS; Zell, ER; Jorgensen, JH; Facklam, RR; Whitney, CG
      Macrolide resistance among invasive Streptococcus pneumoniae isolates

      JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
    77. Waring, AL; Halse, TA; Csiza, CK; Carlyn, CJ; Musser, KA; Limberger, RJ
      Development of a genomics-based PCR assay for detection of Mycoplasma pneumoniae in a large outbreak in New York State

      JOURNAL OF CLINICAL MICROBIOLOGY
    78. Havlir, DV; Torriani, FJ; Schrier, RD; Huang, JY; Lederman, MM; Chervenak, KA; Boom, WH
      Serum interleukin-6 (IL-6), IL-10, tumor necrosis factor (TNF) alpha, soluble type II TNF receptor, and transforming growth factor beta levels in human immunodeficiency virus type 1-infected individuals with Mycobacterium avium complex disease

      JOURNAL OF CLINICAL MICROBIOLOGY
    79. Kenny, GE; Cartwright, FD
      Susceptibilities of Mycoplasma hominis, M-pneumoniae, and Ureaplasma urealyticum to GAR-936, dalfopristin, dirithromycin, evernimicin, gatifloxacin, linezolid, moxifloxacin, quinupristin-dalfopristin, and telithromycin compared to their susceptibilities to reference macrolides, tetracyclines, and quinolones

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    80. Edelstein, PH; Shinzato, T; Doyle, E; Edelstein, MAC
      In vitro activity of gemifloxacin (SB-265805, LB20304a) against Legionellapneumophila and its pharmacokinetics in guinea pigs with L-pneumophila pneumonia

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    81. Bermudez, LE; Inderlied, CB; Kolonoski, P; Wu, M; Aralar, P; Young, LS
      Telithromycin is active against Mycobacterium avium in mice despite lacking significant activity in standard in vitro and macrophage assays and is associated with low frequency of resistance during treatment

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    82. Pradines, B; Rogier, C; Fusai, T; Mosnier, J; Daries, W; Barret, E; Parzy, D
      In vitro activities of antibiotics against Plasmodium falciparum are inhibited by iron

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    83. Piccolomini, R; Di Bonaventura, G; Picciani, C; Laterza, F; Vecchiet, J; Neri, M
      In vitro activity of clarithromycin against intracellular Helicobacter pylori

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    84. Dreses-Werringloer, U; Padubrin, I; Zeidler, H; Kohler, L
      Effects of azithromycin and rifampin on Chlamydia trachomatis infection invitro

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    85. Muller-Serieys, C; Soler, P; Cantalloube, C; Lemaitre, F; Gia, HP; Brunner, F; Andremont, A
      Bronchopulmonary disposition of the ketolide telithromycin (HMR 3647)

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    86. Bentoucha, A; Robert, J; Dega, H; Lounis, N; Jarlier, V; Grosset, J
      Activities of new macrolides and fluoroquinolones against Mycobacterium ulcerans infection in mice

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    87. Edelstein, PH; Higa, F; Edelstein, MAC
      In vitro activity of ABT-773 against Legionella pneumophila, its pharmacokinetics in guinea pigs, and its use to treat guinea pigs with L. pneumophila pneumonia

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    88. Abdelghaffar, H; Vazifeh, D; Labro, MT
      Cellular uptake of two fluoroketolides, HMR 3562 and HMR 3787, by human polymorphonuclear neutrophils in vitro

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    89. Conte, JE; Golden, JA; Kipps, J; Lin, ET; Zurlinden, E
      Effects of AIDS and gender on steady-state plasma and intrapulmonary ethambutol concentrations

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    90. Credito, KL; Lin, GR; Pankuch, GA; Bajaksouzian, S; Jacobs, MR; Appelbaum, PC
      Susceptibilities of Haemophilus influenzae and Moraxella catarrhalis to ABT-773 compared to their susceptibilities to 11 other agents

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    91. Gomi, H; Jiang, ZD; Adachi, JA; Ashley, D; Lowe, B; Verenkar, MP; Steffen, R; Dupont, HL
      In vitro antimicrobial susceptibility testing of bacterial enteropathogenscausing traveler's diarrhea in four geographic regions

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    92. Syrogiannopoulos, GA; Grivea, IN; Tait-Kamradt, A; Katopodis, GD; Beratis, NG; Sutcliffe, J; Appelbaum, PC; Davies, TA
      Identification of an erm(A) erythromycin resistance methylase gene in Streptococcus pneumoniae isolated in Greece

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    93. Gustafsson, I; Engstrand, L; Cars, O
      In vitro pharmacodynamic studies of activities of ketolides HMR 3647 (Telithromycin) and HMR 3004 against extracellular or intracellular Helicobacterpylori

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    94. Becker, AE; de Boer, OJ; van der Wal, AC
      The role of inflammation and infection in coronary artery disease

      ANNUAL REVIEW OF MEDICINE
    95. Stanek, G
      Chlamydia pneumoniae - aetiologic agent of what?

      WIENER KLINISCHE WOCHENSCHRIFT
    96. Fraser-Hurt, N; Bailey, RL; Cousens, S; Mabey, D; Faal, H; Mabey, DCW
      Efficacy of oral azithromycin versus topical tetracycline in mass treatment of endemic trachoma

      BULLETIN OF THE WORLD HEALTH ORGANIZATION
    97. Holm, SO; Jha, HC; Bhatta, RC; Chaudhary, JSP; Thapa, BB; Davis, D; Pokhrel, RP; Miao, YH; Zegans, M; Schachter, J; Frick, KD; Tapert, L; Lietman, TM
      Comparison of two azithromycin distribution strategies for controlling trachoma in Nepal

      BULLETIN OF THE WORLD HEALTH ORGANIZATION
    98. Frick, KD; Lietman, TM; Holm, SO; Jha, HC; Chaudhary, JSP; Bhatta, RC
      Cost-effectiveness of trachoma control measures: comparing targeted household treatment and mass treatment of children

      BULLETIN OF THE WORLD HEALTH ORGANIZATION
    99. Whitcher, JP; Srinivasan, M; Upadhyay, MP
      Corneal blindness: a global perspective

      BULLETIN OF THE WORLD HEALTH ORGANIZATION
    100. Bailey, R; Lietman, T
      The SAFE strategy for the elimination of trachoma by 2020: will it work?

      BULLETIN OF THE WORLD HEALTH ORGANIZATION


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Documento generato il 26/10/20 alle ore 05:32:42