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Mass spectrometric characterization of proteins extracted from Jurkat T cell detergent-resistant membrane domains
PROTEOMICS
17-beta-estradiol alters Jurkat lymphocyte cell cycling and induces apoptosis through suppression of Bcl-2 and cyclin A
INTERNATIONAL IMMUNOPHARMACOLOGY
In vivo modulation of the distribution of thymocyte subsets by female sex steroid hormones
INTERNATIONAL IMMUNOPHARMACOLOGY
Regulation of the helix-loop-helix proteins, E2A and Id3, by the Ras-ERK MAPK cascade
NATURE IMMUNOLOGY
Disruption of T cell signaling networks and development by Grb2 haploid insufficiency
NATURE IMMUNOLOGY
Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not T(H)2 cytokines
NATURE IMMUNOLOGY
Immunologic approaches to the management of pancreatic cancer
CANCER JOURNAL
Decreases in interleukin-4 secretion by invariant CD4(-)CD8(-)V alpha 24J alpha Q T cells in peripheral blood of patients with relapsing-remitting multiple sclerosis
CLINICAL IMMUNOLOGY
Circulating V alpha 24(+) V beta 11(+) NKT cell numbers are decreased in awide variety of diseases that are characterized by autoreactive tissue damage
CLINICAL IMMUNOLOGY
Cbl: Many adaptations to regulate protein tyrosine kinases
NATURE REVIEWS MOLECULAR CELL BIOLOGY
Protein-protein interactions, cytoskeletal regulation and neuronal migration
NATURE REVIEWS NEUROSCIENCE
Mass spectrometric characterization of proteins extracted from Jurkat T cell detergent-resistant membrane domains
EUROPEAN JOURNAL OF MASS SPECTROMETRY
The actin cytoskeleton is required for the trafficking of the B cell antigen receptor to the late endosomes
TRAFFIC
Floating the raft hypothesis for immune receptors: Access to rafts controls receptor signaling and trafficking
TRAFFIC
Inhibitors of p56(lck): assessing their potential as tools for manipulating T-lymphocyte activation
EXPERT OPINION ON THERAPEUTIC PATENTS
Radioimmunotherapy - Potential as a therapeutic strategy in non-Hodgkin's lymphoma
BIODRUGS
HIV nephropathy and the Duffy antigen/receptor for chemokines in African Americans
JOURNAL OF NEPHROLOGY
Defect of lck in a patient with common variable immunodeficiency
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
B-cell kinase Lyn deficiency in patients with systemic lupus erythematosus
JOURNAL OF INVESTIGATIVE MEDICINE
Signal-transduction defects in T cells
CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY
p27Kip1 localizes to detergent-insoluble microdomains within lymphocyte membranes
MOLECULAR MEDICINE
The membrane-microfilament linker ezrin is involved in the formation of the immunological synapse and in T cell activation
IMMUNITY
Distinct patterns of membrane microdomain partitioning in Th1 and Th2 cells
IMMUNITY
Inhibition of beta 2 integrin receptor and Syk kinase signaling in monocytes by the Src family kinase Fgr
IMMUNITY
The Src-like adaptor protein downregulates the T cell receptor on CD4(+)CD8(+) thymocytes and regulates positive selection
IMMUNITY
WASP recruitment to the T cell : APC contact site occurs independently of Cdc42 activation
IMMUNITY
How much TCR does a T cell need?
IMMUNITY
Involvement of SHP-1 tyrosine phosphatase in TCR-mediated signaling pathways in lipid rafts
IMMUNITY
Pax5/BSAP maintains the identity of B cells in late B lymphopoiesis
IMMUNITY
Negative selection at the pre-BCR checkpoint elicited by human mu heavy chains with unusual CDR3 regions
IMMUNITY
Strength of signaling by CD4 and CD8 coreceptor tails determines the number but not the lineage direction of positively selected thymocytes
IMMUNITY
A kinetic window constricts the T cell receptor repertoire in the thymus
IMMUNITY
Notch1 regulates maturation of CD4(+) and CD8(+) thymocytes by modulating TCR signal strength
IMMUNITY
NFATc1 and NFATc2 together control both T and B cell activation and differentiation
IMMUNITY
Activation and anergy in bone marrow B cells of a novel immunoglobulin transgenic mouse that is both hapten specific and autoreactive
IMMUNITY
Analysis of C-MYC function in normal cells via conditional gene-targeted mutation
IMMUNITY
CD79: A review
APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY
A novel quality control compartment derived from the endoplasmic reticulum
MOLECULAR BIOLOGY OF THE CELL
Glycosylphosphatidyl inositol-anchored proteins and fyn kinase assemble innoncaveolar plasma membrane microdomains defined by reggie-1 and-2
MOLECULAR BIOLOGY OF THE CELL
The value of clonality in the diagnosis and follow-up of patients with cutaneous T-cell infiltrates
DIAGNOSTIC MOLECULAR PATHOLOGY
Characterization of NKT cells in human peripheral blood and decidual lymphocytes
AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
Extinguishing maternal immune responses during pregnancy: implications forimmunosuppression
SEMINARS IN IMMUNOLOGY
Fc epsilon RI as a paradigm for a lipid raft-dependent receptor in hematopoietic cells
SEMINARS IN IMMUNOLOGY
Co-stimulation and counter-stimulation: lipid raft clustering controls TCRsignaling and functional outcomes
SEMINARS IN IMMUNOLOGY
Changes in the T cell receptor macromolecular signaling complex and membrane microdomains during T cell development and activation
SEMINARS IN IMMUNOLOGY
Genetic ablation of the src kinase p59fynT exacerbates pulmonary inflammation in an allergic mouse model
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
A nondeletional mechanism for central T-cell tolerance
CRITICAL REVIEWS IN IMMUNOLOGY
T-cell receptor-derived peptides in immunoregulation and therapy of retrovirally induced immunosuppression
CRITICAL REVIEWS IN IMMUNOLOGY
Isolation and characterization of sea urchin egg lipid rafts and their possible function during fertilization
MOLECULAR REPRODUCTION AND DEVELOPMENT
Sarcoidosis
INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE
Activation of mouse B lymphocyte by proteins containing hexahistidine
MOLECULES AND CELLS
A phage display selected Fab fragment with MHC class I-restricted specificity for MAGE-A1 allows for retargeting of primary human T lymphocytes
GENE THERAPY
Evolution and the molecular basis of somatic hypermutation of antigen receptor genes
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES
Detection of early gene expression changes during activation of human primary lymphocytes by in vitro synthesis of proteins from polysome-associated mRNAs
PROTEIN SCIENCE
Prolactin receptor signal transduction
LUPUS
Unmodified and phosphorylated prolactin and gamma delta T cell developmentand function
LUPUS
Viruses and apoptosis
INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY
Multiple co-stimulatory signals are required for triggering proliferation of T cells from human secondary lymphoid tissue
INTERNATIONAL IMMUNOLOGY
CD40-mediated signaling in monocytic cells: up-regulation of tumor necrosis factor receptor-associated factor mRNAs and activation of mitogen-activated protein kinase signaling pathways
INTERNATIONAL IMMUNOLOGY
A potential role for protein tyrosine kinase p56(lck) in rheumatoid arthritis synovial fluid T lymphocyte hyporesponsiveness
INTERNATIONAL IMMUNOLOGY
Determination of the tyrosine phosphorylation sites in the T cell transmembrane glycoprotein CD5
INTERNATIONAL IMMUNOLOGY
Conserved transmembrane tyrosine residues of the TCR beta chain are required for TCR expression and function in primary T cells and hybridomas
INTERNATIONAL IMMUNOLOGY
Truncation of the mu heavy chain alters BCR signalling and allows recruitment of CD5(+) B cells
INTERNATIONAL IMMUNOLOGY
TCR dynamics on the surface of living T cells
INTERNATIONAL IMMUNOLOGY
Functional differences between influenza A-specific cytotoxic T lymphocyteclones expressing dominant and subdominant TCR
INTERNATIONAL IMMUNOLOGY
The involvement of the proto-oncogene p120 c-Cbl and ZAP-70 in CD2-mediated T cell activation
INTERNATIONAL IMMUNOLOGY
T cells in mice expressing a transgenic human TCR beta chain get positively selected but cannot be activated in the periphery by signaling through TCR
INTERNATIONAL IMMUNOLOGY
New views of BCR structure and organization
CURRENT OPINION IN IMMUNOLOGY
Proximal protein tyrosine kinases it immunoreceptor signaling
CURRENT OPINION IN IMMUNOLOGY
Adapters in lymphocyte signalling
CURRENT OPINION IN IMMUNOLOGY
B1 cells: similarities and differences with other B cell subsets
CURRENT OPINION IN IMMUNOLOGY
BCR signals target p27(Kip1) and cyclin D2 via the PI3-K signalling pathway to mediate cell cycle arrest and apoptosis of WEHI 231 B cells
ONCOGENE
The transmembrane adapter LAT plays a central role in immune receptor signalling
ONCOGENE
The role of Gads in hematopoietic cell signalling
ONCOGENE
Beyond the RING: CBL proteins as multivalent adapters
ONCOGENE
Leukocyte-specific adaptor protein Grap2 interacts with hematopoietic progenitor kinase 1 (HPK1) to activate JNK signaling pathway in T lymphocytes
ONCOGENE
Pathogenesis of Shiga toxin-induced hemolytic uremic syndrome
PEDIATRIC NEPHROLOGY
Antagonists of the Src homology 2 (SH2) domains of Grb2, Src, Lck and ZAP-70
CURRENT MEDICINAL CHEMISTRY
Regulation of Pyk2 expression by p56(Lck) in Jurkat T lymphocytes
CELLULAR SIGNALLING
The mimicry of human glycolipids and glycosphingolipids by the lipooligosaccharides of pathogenic Neisseria and Haemophilus
JOURNAL OF AUTOIMMUNITY
An absolute requirement for Fyn in T cell receptor-induced caspase activation and apoptosis
FASEB JOURNAL
Expression of B cell receptor-associated signaling molecules in human lupus
AUTOIMMUNITY
Detection of minimal residual disease in peripheral blood prior to clinical relapse of childhood acute lymphoblastic leukaemia using PCR
MOLECULAR AND CELLULAR PROBES
Development and application of receptor-modified T lymphocytes for adoptive immunotherapy
TRANSFUSION MEDICINE REVIEWS
Quantification of minimal residual disease in children with oligoclonal B-precursor acute lymphoblastic leukemia indicates that the clones that grow out during relapse already have the slowest rate of reduction during induction therapy
LEUKEMIA
A new method to model membrane protein structure based on silent amino acid substitutions
PROTEINS-STRUCTURE FUNCTION AND GENETICS
Cross-reactivity in T-cell antigen recognition
IMMUNOLOGY AND CELL BIOLOGY
Interplay between telomere length and telomerase in human leukocyte differentiation and aging
JOURNAL OF LEUKOCYTE BIOLOGY
Rafts and synapses in the spatial organization of immune cell signaling receptors
JOURNAL OF LEUKOCYTE BIOLOGY
Role of Src kinases and Syk in Fc gamma receptor-mediated phagocytosis andphagosome-lysosome fusion
JOURNAL OF LEUKOCYTE BIOLOGY
Crystal-induced neutrophil activation. VII. Involvement of Syk in the responses to monosodium urate crystals
JOURNAL OF LEUKOCYTE BIOLOGY
Biliary glycoprotein (BGPa, CD66a, CEACAM1) mediates inhibitory signals
JOURNAL OF LEUKOCYTE BIOLOGY
Signaling networks regulating beta 1 integrin-mediated adhesion of T lymphocytes to extracellular matrix
JOURNAL OF LEUKOCYTE BIOLOGY
Molecular motors involved in T cell receptor clusterings
JOURNAL OF LEUKOCYTE BIOLOGY
Calcium signaling mechanisms in T lymphocytes
ANNUAL REVIEW OF IMMUNOLOGY
High dose of dexamethasone upregulates TCR/CD3-induced calcium response independent of TCR zeta chain expression in human T lymphocytes
JOURNAL OF CELLULAR BIOCHEMISTRY
A role for lipid rafts in immune cell signaling
MICROBIOLOGY AND IMMUNOLOGY
CD5 (OKT1) augments CD3-mediated intracellular signaling events in human Tlymphocytes
INFLAMMATION
Selective reduction and recovery of invariant V alpha 24Ja alpha Q T cell receptor T cells in correlation with disease activity in patients with systemic lupus erythematosus
JOURNAL OF RHEUMATOLOGY
Structural analysis of TCR alpha and beta chains from human T-cell clones specific for small nuclear ribonucleoprotein polypeptides Sm-D, Sm-B and U1-70 kDa: TCR complementarity determining region 3 usage appears highly conserved
SCANDINAVIAN JOURNAL OF IMMUNOLOGY