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    1. Chidiac, P
      Considerations in the evaluation of inverse agonism and protean agonism atG protein-coupled receptors

      G PROTEIN PATHWAYS, PT A, RECEPTORS
    2. Hruby, VJ; Qiu, W; Okayama, T; Soloshonok, VA
      Design of nonpeptides from peptide ligands for peptide receptors

      G PROTEIN PATHWAYS, PT A, RECEPTORS
    3. Leurs, R; Hoffmann, M; Alewijnse, AE; Smit, MJ; Timmerman, H
      Methods to determine the constitutive activity of histamine H-2 receptors

      G PROTEIN PATHWAYS, PT A, RECEPTORS
    4. Jeffery, P
      Inflammation and remodeling in the adult and child with asthma

      PEDIATRIC PULMONOLOGY
    5. Lemanske, RF
      Origins and treatment of airway inflammation in childhood asthma

      PEDIATRIC PULMONOLOGY
    6. Becker, A
      Controversies and challenges of exercise-induced bronchoconstriction and their implications for children

      PEDIATRIC PULMONOLOGY
    7. Skoner, D
      Montelukast in 2-to 5-year-old children with asthma

      PEDIATRIC PULMONOLOGY
    8. Canning, BJ; Reynolds, SM; Mazzone, SB
      Multiple mechanisms of reflex bronchospasm in guinea pigs

      JOURNAL OF APPLIED PHYSIOLOGY
    9. Fannon, SA; Vidaver, RM; Marts, SA
      Genome and hormones: Gender differences in physiology - Historical perspectives: An abridged history of sex steroid hormone receptor action

      JOURNAL OF APPLIED PHYSIOLOGY
    10. Rubinstein, I; Chandilawa, R; Dagar, S; Hong, D; Gao, XP
      Adenosine A1 receptors mediate plasma exudation from the oral mucosa

      JOURNAL OF APPLIED PHYSIOLOGY
    11. Yaksh, TL; Ozaki, G; McCumber, D; Rathbun, M; Svensson, C; Malkmus, S; Yaksh, MC
      An automated flinch detecting system for use in the formalin nociceptive bioassay

      JOURNAL OF APPLIED PHYSIOLOGY
    12. Hoshikawa, Y; Ono, S; Suzuki, S; Tanita, T; Chida, M; Song, C; Noda, M; Tabata, T; Voelkel, NF; Fujimura, S
      Generation of oxidative stress contributes to the development of pulmonaryhypertension induced by hypoxia

      JOURNAL OF APPLIED PHYSIOLOGY
    13. Calvijo, LC; Carter, MB; Matheson, PJ; Wilson, MA; Wead, WB; Garrison, RN
      PAF increases vascular permeability without increasing pulmonary arterial pressure in the rat

      JOURNAL OF APPLIED PHYSIOLOGY
    14. Doyle, MP; Hu, WH
      A new enantioselective synthesis of milnacipran and an analogue by catalytic asymmetric cyclopropanation

      ADVANCED SYNTHESIS & CATALYSIS
    15. Kitaori, K; Furukawa, Y; Yoshimoto, H; Otera, J
      Integrated chemical process: Convenient synthesis of enantiopure 2-hydroxymethyl-1,4-benzodioxane derivatives under iterative catalysis of CsF

      ADVANCED SYNTHESIS & CATALYSIS
    16. Tu, SJ; Deng, X; Du, M; Fang, YY; Guo, YM; Liu, XH
      9-(4-chlorophenyl)-3,3,6,6-tetramethyl-1,2,3,4,5,6,7,8,9,10-decahydroacridine-1,8-dione

      ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE
    17. Wingertzahn, MA; Ochs, RS
      Changes in ryanodine receptor-mediated calcium release during skeletal muscle differentiation. II. Resolution of a caffeine-ryanodine paradox

      EXPERIMENTAL BIOLOGY AND MEDICINE
    18. Gutmann, JN; Corson, SL
      Female reproductive endocrinology at the turn of the millennium

      INTERNATIONAL JOURNAL OF FERTILITY AND WOMENS MEDICINE
    19. Rhodes, J; Mickleborough, TD; Owiny, J; Tucker, A
      Anesthesia protocol for hyperpnea-induced airway obstruction in the guineapig

      COMPARATIVE MEDICINE
    20. Kamimura, E; Ueno, Y; Tanaka, S; Sawa, H; Yoshioka, M; Ueno, K; Inoue, T; Li, XB; Koyama, T; Ishikawa, R; Nagashima, K
      New rat model for attention deficit hyperactive disorder (ADHD)

      COMPARATIVE MEDICINE
    21. Kizawa, Y; Ohuchi, N; Saito, K; Kusama, T; Murakami, H
      Effects of endothelin-1 and nitric oxide on proliferation of cultured guinea pig bronchial smooth muscle cells

      COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
    22. Diedrich, K; Ludwig, M; Felberbaum, RE
      The role of gonadotropin-releasing hormone antagonists in in vitro fertilization

      SEMINARS IN REPRODUCTIVE MEDICINE
    23. Ozoe, Y; Akamatsu, M
      Non-competitive GABA antagonists: probing the mechanisms of their selectivity for insect versus mammalian receptors

      PEST MANAGEMENT SCIENCE
    24. Jacobson, KA; Ravi, RG; Nandanan, E; Kim, HS; Moro, S; Kim, YC; Lee, K; Barak, D; Marquez, VE; Ji, XD
      Ribose modified nucleosides and nucleotides as ligands for purine receptors

      NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
    25. Sun, XW; Janvier, P; Zhao, G; Bienayme, H; Zhu, JP
      A novel multicomponent synthesis of polysubstituted 5-aminooxazole and itsnew scaffold-generating reaction to pyrrolo[3,4-b]pyridine

      ORGANIC LETTERS
    26. Greig, IR; Tozer, MJ; Wright, PT
      Synthesis of cyclic sulfonamides through intramolecular Diels-Alder reactions

      ORGANIC LETTERS
    27. Houghton, TJ; Choi, S; Rawal, VH
      Efficient assembly of the phomactin core via two different macrocyclization protocols

      ORGANIC LETTERS
    28. Chemler, SR; Iserloh, U; Danishefsky, SJ
      Enantioselective synthesis of the oxadecalin core of phomactin A via a highly stereoselective Diels-Alder reaction

      ORGANIC LETTERS
    29. Gomez-Vidal, JA; Silverman, RB
      Short, highly efficient syntheses of protected 3-azido- and 4-azidoprolineand their precursors

      ORGANIC LETTERS
    30. Mi, BY; Maleczka, RE
      A Nozaki-Hiyama-Kishi Ni(II)/Cr(II) coupling approach to the phomactins

      ORGANIC LETTERS
    31. McCollam, PL; Lage, MJ; Bala, M
      A comparison of total hospital costs for percutaneous coronary intervention patients receiving abciximab versus tirofiban

      CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
    32. Paradiso-Hardy, FL; Madan, M; Radhakrishnan, S; Hurden, S; Cohen, EA
      Severe thrombocytopenia possibly related to readministration of eptifibatide

      CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
    33. Huang, JQ; Hunt, RH
      Pharmacological and pharmacodynamic essentials of H-2-receptor antagonistsand proton pump inhibitors for the practising physician

      BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY
    34. Bytzer, P; Talley, NJ
      Current indications for acid suppressants in dyspepsia

      BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY
    35. Howden, CW; Leontiadis, GI
      Current indications for acid suppressants in Helicobacter pylori-negative ulcer disease

      BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY
    36. Chan, FKL; Sung, JJY
      Role of acid suppressants in prophylaxis of NSAID damage

      BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY
    37. Hanrahan, JR; Mewett, KN; Chebib, M; Burden, PM; Johnston, GAR
      An improved, versatile synthesis of the GABA(C) antagonists (1,2,5,6-tetrahydropyridin-4-yl)methylphosphinic acid (TPMPA) and (piperidin-4-yl)methylphosphinic acid (P4MPA)

      JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
    38. Reichert, A; Frohlich, R; Ferguson, R; Kraft, A
      Binding interactions between 3-aryl-1,2,4-oxadiazol-5-ones and a trisimidazoline base

      JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
    39. Frackenpohl, J; Braje, WM; Hoffmann, HMR
      Cross-coupling reactions in Cinchona alkaloid chemistry: aryl-substituted and dimeric quinine, quinidine, as well as quincorine and quincoridine derivatives

      JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
    40. Falus, A; Hegyesi, H; Lazar-Molnar, E; Pos, Z; Laszlo, V; Darvas, Z
      Paracrine and autocrine interactions in melanoma: histamine is a relevant player in local regulation

      TRENDS IN IMMUNOLOGY
    41. Hasan, J; Jayson, GC
      VEGF antagonists

      EXPERT OPINION ON BIOLOGICAL THERAPY
    42. Craig, AG; DeBoard, R; Kirby, D; Jiang, GC; Koerber, SC; Rivier, JE
      Characterization of betidamino acid-containing somatostatin and gonadotropin-releasing hormone analogs with electrospray mass spectrometry and tandemmass spectrometry

      EUROPEAN JOURNAL OF MASS SPECTROMETRY
    43. Schwinn, DA
      The role of alpha(1)-adrenergic receptor subtypes in lower urinary tract symptoms

      BJU INTERNATIONAL
    44. Testa, R; Guarneri, L; Angelico, P; Velasco, C; Poggesi, E; Cilia, A; Leonardi, A
      Effect of different 5-hydroxytryptamine receptor subtype antagonists on the micturition reflex in rats

      BJU INTERNATIONAL
    45. Felmeden, DC; Lip, GYH; Beevers, G
      Calcium antagonists in diabetic hypertension

      DIABETES OBESITY & METABOLISM
    46. Castelot-Deliencourt, G; Roger, E; Pannecoucke, X; Quirion, JC
      Diastereoselective synthesis of chiral amidophosphonates by 1,5-asymmetricinduction

      EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
    47. Thoma, G; Magnani, JL; Patton, JT; Ernst, B; Jahnke, W
      Preorganization of the bioactive conformation of sialyl Lewis(X) analoguescorrelates with their affinity to E-selectin

      ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
    48. Regoli, D; Rizzi, A; Perron, SI; Gobeil, F
      Classification of kinin receptors

      BIOLOGICAL CHEMISTRY
    49. Stewart, JM; Gera, L; York, EJ; Chan, DC; Whalley, EJ; Bunn, PA; Vavrek, RJ
      Metabolism-resistant bradykinin antagonists: Development and applications

      BIOLOGICAL CHEMISTRY
    50. Hess, JF; Hey, PJ; Chen, TB; O'Brien, J; Omalley, SS; Pettibone, DJ; Chang, RSL
      Molecular cloning and pharmacological characterization of the canine B1 and B2 bradykinin receptors

      BIOLOGICAL CHEMISTRY
    51. De Vos, C; Rihoux, JP
      H-1-antihistamines

      NEW DRUGS FOR ASTHMA, ALLERGY AND COPD
    52. Rogers, DF
      Mucus regulation

      NEW DRUGS FOR ASTHMA, ALLERGY AND COPD
    53. Sabroe, I; Williams, TJ
      Chemokines: An overview

      NEW DRUGS FOR ASTHMA, ALLERGY AND COPD
    54. Garber, SL; Mirochnik, Y; Arruda, JAL; Dunea, G; Slobodskoy, L
      Differential effects of enalapril and irbesartan in experimental papillarynecrosis

      KIDNEY & BLOOD PRESSURE RESEARCH
    55. Tepel, M; van der Giet, M; Zidek, W
      Efficacy and tolerability of angiotensin II type 1 receptor antagonists indialysis patients using AN69 dialysis membranes

      KIDNEY & BLOOD PRESSURE RESEARCH
    56. Schimanski, S; Scofield, MA; Wangemann, P
      Functional beta(2)-adrenergic receptors are present in nonstrial tissues of the lateral wall in the gerbil cochlea

      AUDIOLOGY AND NEURO-OTOLOGY
    57. Zeltser, I; Ben-Aziz, O; Schefler, I; Bhargava, K; Altstein, M; Gilon, C
      Insect neuropeptide antagonist. Part II. Synthesis and biological activityof backbone cyclic and precyclic PBAN antagonists

      JOURNAL OF PEPTIDE RESEARCH
    58. Ahmed, SI; Wibowo, F; Gembitsky, DS; Bozso, Z; Murphy, RF; Lovas, S
      Importance of the C-terminal phenylalanine of gastrin for binding to the human CCK2 receptor

      JOURNAL OF PEPTIDE RESEARCH
    59. Ahn, JM; Medeiros, M; Trivedi, D; Hruby, VJ
      Development of potent glucagon antagonists: structure-activity relationship study of glycine at position 4

      JOURNAL OF PEPTIDE RESEARCH
    60. Fridkin, G; Gilon, T; Loyter, A; Gilon, C
      Systematic solid-phase synthesis of linear pseudooligolysines containing multiple adjacent CH2NH amide bond surrogates: potential agents for gene delivery

      JOURNAL OF PEPTIDE RESEARCH
    61. Henlin, JM; Boutin, JA; Duchene-Roger, F; Nicolas, JP; Desmet-Beaufort, C; Levens, N; Fauchere, JL
      Parallel synthesis and pharmacological screening oi nonpeptide ligands of the neuropeptide Y receptor subtype Y-5

      JOURNAL OF PEPTIDE RESEARCH
    62. Liao, S; Shenderovich, M; Kover, KE; Zhang, Z; Hosohata, K; Davis, P; Porreca, F; Yamamura, HI; Hruby, VJ
      Synthesis, biology, NMR and conformation studies of the topographically constrained delta-opioid selective peptide analogs of [beta-iPrPhe(3)]deltorphin I

      JOURNAL OF PEPTIDE RESEARCH
    63. Guerrini, R; Calo', G; Bigoni, R; Rizzi, D; Regoli, D; Salvadori, S
      Structure-activity relationship of [Nphe(1)]-NC-(1-13)-NH2, a pure and selective nociceptin/orphanin FQ receptor antagonist

      JOURNAL OF PEPTIDE RESEARCH
    64. Lempicka, E; Derdowska, I; Jastrzebska, B; Kuncarova, P; Slaninova, J; Lammek, B
      Analogs of oxytocin conformationally restricted in the N-terminal part of the molecule

      JOURNAL OF PEPTIDE RESEARCH
    65. Derdowska, I; Prahl, A; Neubert, K; Hartrodt, B; Kania, A; Dobrowolski, D; Melhem, S; Trzeciak, HI; Wierzba, T; Lammek, B
      New analogues of bradykinin containing a conformationally restricted dipeptide fragment in their molecules

      JOURNAL OF PEPTIDE RESEARCH
    66. Ma, Y; Lang, LX; Kiesewetter, DO; Jagoda, E; Sassaman, MB; Der, M; Eckelman, WC
      Liquid chromatography-tandem mass spectrometry identification of metabolites of two 5-HT1A antagonists, N-{2-[4-(2-methoxylphenyl)piperazino]ethyl}-N-(2-pyridyl) trans- and cis-4-fluorocyclohexanecarboxamide, produced by human and rat hepatocytes

      JOURNAL OF CHROMATOGRAPHY B
    67. Tois, J; Franzen, R; Aitio, O; Laakso, I; Huuskonen, J; Taskinen, J
      Solid-phase bromination and Suzuki coupling of 2-carboxyindoles

      COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
    68. Mason, JS; Good, AC; Martin, EJ
      3-D Pharmacophores in drug discovery

      CURRENT PHARMACEUTICAL DESIGN
    69. McCormack, JG; Westergaard, N; Kristiansen, M; Brand, CL; Lau, J
      Pharmacological approaches to inhibit endogenous glucose production as a means of anti-diabetic therapy

      CURRENT PHARMACEUTICAL DESIGN
    70. Jungmann, EM; Mercey, D; DeRuiter, A; Edwards, S; Donoghue, S; Booth, T; Mohan, D; Lyall, H; Taylor, GP
      Is first trimester exposure to the combination of antiretroviral therapy and folate antagonists a risk factor for congenital abnormalities?

      SEXUALLY TRANSMITTED INFECTIONS
    71. Eri, LM; Tveter, KJ
      Effects of bicalutamide and leuprolide on prostate-specific antigen (PSA),acid phosphatase (ACP) and prostatic acid phosphatase (PAP) in men with benign prostatic hyperplasia (BPH)

      PROSTATE CANCER AND PROSTATIC DISEASES
    72. Vallancien, G; Pariente, P
      Treatment of lower urinary tract symptoms suggestive of benign prostatic obstruction in real life practice in France

      PROSTATE CANCER AND PROSTATIC DISEASES
    73. Lepre, CA
      Library design for NMR-based screening

      DRUG DISCOVERY TODAY
    74. Burns, DJ; Kofron, JL; Warrior, U; Beutel, BA
      Well-less, gel-permeation formats for ultra-HTS

      DRUG DISCOVERY TODAY
    75. White, WB
      Cardiovascular risk and therapeutic intervention for the early morning surge in blood pressure and heart rate

      BLOOD PRESSURE MONITORING
    76. Littlejohn, TW
      Clinical considerations in hypertensive black patients: the role of angiotensin II receptor blockers in combination with a diuretic

      BLOOD PRESSURE MONITORING
    77. Nair, RR; Nair, P
      Age-dependent variation in contractility of adult cardiac myocytes

      INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
    78. Santini, D; Vincenzi, B; Fossati, C; D'Angelillo, RM; Patti, G; Bianco, V; Avvisati, G; Tonini, G
      Prevention of delayed emesis induced by moderately emetogenic chemotherapyin patients with acute emesis - A pilot study with ACTH-Depot plus tropisetron

      MEDICAL ONCOLOGY
    79. Bearn, J; Bennett, J; Martin, T; Gossop, M; Strang, J
      The impact of naloxone/lofexidine combination treatment on the opiate withdrawal syndrome

      ADDICTION BIOLOGY
    80. Wu, CF; Liu, J; Liu, W; Consolo, S
      Failure of 5-HT3 receptors in regulation of ethanol-induced ascorbic acid release in rat striatum

      ADDICTION BIOLOGY
    81. Brown, MJ
      Hypertension - Matching the right drug to the right patient in essential hypertension

      HEART
    82. Del Compare, JA; Aguirre, JA; Ibarra, FR; Barontini, M; Armando, I
      Effects of thyroid hormone on the renal dopaminergic system

      ENDOCRINE
    83. Wang, L; Xie, LP; Zhang, RQ
      Gene expression of gonadotropin-releasing hormone and its receptor in rat pancreatic cancer cell lines

      ENDOCRINE
    84. Bujdoso, E; Jaszberenyi, M; Tomboly, C; Toth, G; Telegdy, G
      Effects of endomorphin-1 on open-field behavior and on the hypothalamic-pituitary-adrenal system

      ENDOCRINE
    85. Tilton, RG; Brock, TA; Dixon, RAF
      Therapeutic potential of endothelin receptor antagonists and nitric oxide donors in pulmonary hypertension

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    86. Fernandez-Botran, R
      A small-molecule antagonist of human and murine CCR1 receptors

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    87. Mizejewski, GJ
      Peptides as receptor ligand drugs and their relationship to G-coupled signal transduction

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    88. Nicholson, CD; Lensing, AWA
      Old antithrombotics: ready to retire?

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    89. Rosenzweig, EB; Barst, RJ
      Novel therapeutics for the treatment of paediatric pulmonary arterial hypertension

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    90. Paranjape, SB; Thibonnier, M
      Development and therapeutic indications of orally-active non-peptide vasopressin receptor antagonists

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    91. Limonta, P; Marelli, MM; Moretti, RM
      LHRH analogues as anticancer agents: pituitary and extrapituitary sites ofaction

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    92. Dao, HH; Moreau, P
      An update on the status of endothelin receptor antagonists for hypertension

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    93. Burnier, M
      Novel angiotensin II inhibitors in cardiovascular medicine

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    94. Wein, AJ
      Pharmacological agents for the treatment of urinary incontinence due to overactive bladder

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    95. Connell, RD; Beebe, JS
      Patent focus on cancer chemotherapeutics. III Angiogenesis agents: October2000-March 2001

      EXPERT OPINION ON THERAPEUTIC PATENTS
    96. Smith, HJ; Nicholls, PJ; Simons, C; Le Lain, R
      Inhibitors of steroidogenesis as agents for the treatment of hormone-dependent cancers

      EXPERT OPINION ON THERAPEUTIC PATENTS
    97. Slassi, A; Isaac, M; Arora, J
      Novel serotonergic and non-serotonergic migraine headache therapies

      EXPERT OPINION ON THERAPEUTIC PATENTS
    98. Norman, P
      Therapeutic approaches to respiratory diseases excluding asthma: Trends from the patent literature 1997-2000

      EXPERT OPINION ON THERAPEUTIC PATENTS
    99. Dogne, JM; de Leval, X; Delarge, J; Masereel, B
      Recent developments of thromboxane modulators

      EXPERT OPINION ON THERAPEUTIC PATENTS
    100. Chaki, S; Nakazato, A
      Recent advances in feeding suppressing agents: potential therapeutic strategy for the treatment of obesity

      EXPERT OPINION ON THERAPEUTIC PATENTS


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Documento generato il 19/02/20 alle ore 17:54:11