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Plasticity in skeletal cardiac, and smooth muscle - Invited review: Pathophysiology of cardiac muscle contraction and relaxation as a result of alterations in thin filament regulation
JOURNAL OF APPLIED PHYSIOLOGY
Hypertrophic cardiomyopathy: from molecular and genetic mechanisms to clinical management
EUROPEAN HEART JOURNAL SUPPLEMENTS
A tropomyosin-2 mutation suppresses a troponin I myopathy in Drosophila
MOLECULAR BIOLOGY OF THE CELL
Complete nucleotide sequences of cDNA encoding for tropomyosin isoforms from the catch muscle of scallop Patinopecten yessoensis
FISHERIES SCIENCE
cDNA cloning and deduced amino acid sequence of tropomyosin from fast skeletal muscle of white croaker Pennahia argentata
FISHERIES SCIENCE
Spectrum of clinical phenotypes and gene variants in cardiac myosin-binding protein C mutation carriers with hypertrophic cardiomyopathy
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
On genetic and phenotypic variability of hypertrophic cardiomyopathy: Nature versus nurture
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
Genetically modified animal models in cardiovascular research
REVISTA ESPANOLA DE CARDIOLOGIA
Cardiac troponin T Arg92Trp mutation and progression from hypertrophic to dilated cardiomyopathy
CLINICAL CARDIOLOGY
Cardiomyopathies: from genetics to the prospect of treatment
LANCET
Impact of cardiac transplantation on molecular pathology of ET-1, VEGF-C, and mitochondrial metabolism and morphology in dilated versus ischemic cardiomyopathic patients
TRANSPLANTATION
Structural basis for bending tropomyosin around actin in muscle thin filaments
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Deciphering the design of the tropomyosin molecule
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
The third and fourth tropomyosin isoforms of Caenorhabditis elegans are expressed in the pharynx and intestines and are essential for development andmorphology
JOURNAL OF MOLECULAR BIOLOGY
The molecular genetic basis for hypertrophic cardiomyopathy
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
Manipulating the contractile apparatus: Genetically defined animal models of cardiovascular disease
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
Development and application of linkage analysis in genetic diagnosis of familial hypertrophic cardiomyopathy
JOURNAL OF MEDICAL GENETICS
Abnormal contractile function in transgenic mice expressing a familial hypeptrophic cardiomyopathy-linked troponin T (I79N) mutation
JOURNAL OF BIOLOGICAL CHEMISTRY
Modulation of myosin function by isoform-specific properties of Saccharomyces cerevisiae and muscle tropomyosins
JOURNAL OF BIOLOGICAL CHEMISTRY
Familial hypertrophic cardiomyopathy mutations in the regulatory light chains of myosin affect their structure, Ca2+ binding, and phosphorylation
JOURNAL OF BIOLOGICAL CHEMISTRY
Effects of troponin T mutations in familial hypertrophic cardiomyopathy onregulatory functions of other troponin subunits
JOURNAL OF BIOCHEMISTRY
A malignant phenotype of hypertrophic cardiomyopathy caused by Arg719Gln cardiac beta-myosin heavy-chain mutation in a Chinese family
CLINICA CHIMICA ACTA
Novel cardiac troponin T mutation as a cause of familial dilated cardiomyopathy
CIRCULATION
Hypertrophic cardiomyopathy - Histopathological features of sudden death in cardiac troponin T disease
CIRCULATION
Disease-causing mutations in cardiac troponin T: Identification of a critical tropomyosin-binding region
BIOPHYSICAL JOURNAL
Importance of internal regions and the overall length of tropomyosin for actin binding and regulatory function
BIOCHEMISTRY
Local heterogeneity in the pressure denaturation of the coiled-coil tropomyosin because of subdomain folding units
BIOCHEMISTRY
Regulatory properties of tropomyosin effects of length, isoform, and N-terminal sequence
BIOCHEMISTRY
High-level production of functional muscle alpha-tropomyosin in Pichia pastoris
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Different expressivity of a ventricular essential myosin light chain gene Ala57Gly mutation in familial hypertrophic cardiomyopathy
AMERICAN HEART JOURNAL
The molecular genetics of hypertrophic cardiomyopathy: prognostic implications
EUROPACE
Molecular genetics of cardiomyopathies
JOURNAL OF NUCLEAR CARDIOLOGY
Contractile dysfunction in hypertrophic cardiomyopathy: Elucidating primary defects of mutant contractile proteins by gene transfer
TRENDS IN CARDIOVASCULAR MEDICINE
Physiological consequences of tropomyosin mutations associated with cardiac and skeletal myopathies
JOURNAL OF MOLECULAR MEDICINE-JMM
Crystal structure of tropomyosin at 7 Angstroms resolution
PROTEINS-STRUCTURE FUNCTION AND GENETICS
Myocardial perfusion and sympathetic innervation in patients with hypertrophic cardiomyopathy
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
Unusual association of hypertrophic cardiomyopathy with complete atrioventricular canal defect and Down syndrome
TEXAS HEART INSTITUTE JOURNAL
The human beta-myosin heavy chain gene: Sequence diversity and functional characteristics of the protein
JOURNAL OF CELLULAR BIOCHEMISTRY
Altered hemodynamics in transgenic mice harboring mutant tropomyosin linked to hypertrophic cardiomyopathy
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
Alteration of cardiac myofibrillogenesis by liposome-mediated delivery of exogenous proteins and nucleic acids into whole embryonic hearts
ANATOMY AND EMBRYOLOGY
TGF-beta superfamily members do not promote smooth muscle-specific alternative splicing, a late marker of vascular smooth muscle cell differentiation
DIFFERENTIATION
Identification and treatment of patients with hypertrophhic cardiomyopathyat risk of sudden death
REVISTA ESPANOLA DE CARDIOLOGIA
Genetic aspects of arrhythmias
ZEITSCHRIFT FUR KARDIOLOGIE
Nemaline cardiomyopathy in a young adult: An ultraimmunohistochemical study and review of the literature
ULTRASTRUCTURAL PATHOLOGY
Sudden death in hypertrophic cardiomyopathy.
NEW ENGLAND JOURNAL OF MEDICINE
Tropomyosin and actin isoforms modulate the localization of tropomyosin strands on actin filaments
JOURNAL OF MOLECULAR BIOLOGY
Expression of HCM causing mutations: lessons learnt from genotype-phenotype studies of the South African founder MYH7 A797T mutation
JOURNAL OF MEDICAL GENETICS
Hypertrophic cardiomyopathy: from man to mouse
JOURNAL OF CLINICAL INVESTIGATION
Tropomyosin-dependent filament formation by a polymerization-defective mutant yeast actin (V266G,L267G)
JOURNAL OF BIOLOGICAL CHEMISTRY
Mapping the domain of troponin T responsible for the activation of actomyosin ATPase activity - Identification of residues involved in binding to actin
JOURNAL OF BIOLOGICAL CHEMISTRY
Cooperative interaction between developmentally regulated troponin T and tropomyosin isoforms in the absence of F-actin
JOURNAL OF BIOLOGICAL CHEMISTRY
Altered regulation of cardiac muscle contraction by troponin T mutations that cause familial hypertrophic cardiomyopathy
JOURNAL OF BIOLOGICAL CHEMISTRY
Effect of Arg145Gly mutation in human cardiac troponin I on the ATPase activity of cardiac myofibrils
JOURNAL OF BIOCHEMISTRY
Functional consequences of the deletion mutation Delta Glu160 in human cardiac troponin T
JOURNAL OF BIOCHEMISTRY
Suppressors of mdm20 in yeast identify new alleles of ACT1 and TPM1 predicted to enhance actin-tropomyosin interactions
GENETICS
Mitogen-induced up-regulation of non-smooth muscle isoform of alpha-tropomyosin in rat aortic smooth muscle cells
EUROPEAN JOURNAL OF PHARMACOLOGY
Complexes of smooth muscle tropomyosin with F-actin studied by differential scanning calorimetry
EUROPEAN JOURNAL OF BIOCHEMISTRY
Amino-acid replacements in an internal region of tropomyosin alter the properties of the entire molecule
EUROPEAN JOURNAL OF BIOCHEMISTRY
Investigation of a truncated cardiac troponin T that causes familial hypertrophic cardiomyopathy - Ca2+ regulatory properties of reconstituted thin filaments depend on the ratio of mutant to wild-type protein
CIRCULATION RESEARCH
Clinical features of hypertrophic cardiomyopathy caused by a Lys183 deletion mutation in the cardiac troponin I gene
CIRCULATION
Homozygous mutation in cardiac troponin T - Implications for hypertrophic cardiomyopathy
CIRCULATION
A newly created splice donor site in exon 25 of the MyBP-C gene is responsible for inherited hypertrophic cardiomyopathy with incomplete disease penetrance
CIRCULATION
Temporal repolarization lability in hypertrophic cardiomyopathy caused by beta-myosin heavy-chain gene mutations
CIRCULATION
Transgenic rat hearts expressing a human cardiac troponin T deletion reveal diastolic dysfunction and ventricular arrhythmias
CARDIOVASCULAR RESEARCH
Phenotypic variation of familial hypertrophic: cardiomyopathy caused by the Phe110 -> IIe mutation in cardiac troponin T
CARDIOLOGY
Alteration of tropomyosin function and folding by a nemaline myopathy-causing mutation
BIOPHYSICAL JOURNAL
Three-dimensional reconstruction of thin filaments containing mutant tropomyosin
BIOPHYSICAL JOURNAL
Actomyosin regulatory properties of yeast tropomyosin are dependent upon N-terminal modification
BIOCHEMISTRY
Tropomyosin 3 increases striated muscle isoform diversity
BIOCHEMISTRY
Independent functions for the N- and C-termini in the overlap region of tropomyosin
BIOCHEMISTRY
Inherited disorders of sarcomeric proteins
CURRENT OPINION IN NEUROLOGY
In vivo short-term expression of a hypertrophic cardiomyopathy mutation inadult rabbit myocardium: Myofibrillar incorporation without early disarray
PROCEEDINGS OF THE ASSOCIATION OF AMERICAN PHYSICIANS
Morbidity outcome in patients with hypertrophic obstructive cardiomyopathyundergoing cardiac septal myectomy: Early-extubation anesthesia versus high-dose opioid anesthesia technique
JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA
Immunochemical identification and immunofluorescent localization of tropomyosin in germinated pollen of Lilium davidii
PROGRESS IN NATURAL SCIENCE
Cis and trans effects of the myotonic dystrophy (DM) mutation in a cell culture model
HUMAN MOLECULAR GENETICS
Homozygosity for a nonsense mutation in the alpha-tropomyosin slow gene TPM3 in a patient with severe infantile nemaline myopathy
NEUROMUSCULAR DISORDERS
Two skeletal alpha-tropomyosin transcripts with distinct 3 ' UTR have different temporal and spatial patterns of expression in the striated muscle lineages of Xenopus laevis
MECHANISMS OF DEVELOPMENT
Cloning and sequencing of cDNA for akazara scallop tropomyosin
FISHERIES SCIENCE
TGF-beta 1-dependent differential expression of a rat homolog for latent TGF-beta binding protein in astrocytes and C6 glioma cells
GLIA
Close physical linkage of human troponin genes: Organization, sequence, and expression of the locus encoding cardiac troponin I acid slow skeletal troponin T
GENOMICS
Fine-structure mapping of the hereditary inclusion body myopathy locus
GENOMICS
Survival after cardiac arrest or sustained ventricular tachycardia in patients with hypertrophic cardiomyopathy
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
Functional changes in troponin T by a splice donor site mutation that causes hypertrophic cardiomyopathy
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
Genetic basis of cardiomyopathy
CURRENT OPINION IN CARDIOLOGY
Characterisation of troponin-T from salmonid fish
JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY
Fluorescence properties of recombinant tropomyosin containing tryptophan, 5-hydroxytryptophan and 7-azatryptophan
PHOTOCHEMISTRY AND PHOTOBIOLOGY
P57(Kip2) expression is enhanced during mid-cardiac murine development andis restricted to trabecular myocardium
PEDIATRIC RESEARCH
Fast skeletal muscle troponin T increases the cooperativity of transgenic mouse cardiac muscle contraction
JOURNAL OF PHYSIOLOGY-LONDON
The cardiac troponin I gene is not associated with hypertrophic cardiomyopathy in patients from eastern Finland
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
Gene duplication and recruitment of a specific tropomyosin into striated muscle cells in the jellyfish Podocoryne carnea
JOURNAL OF EXPERIMENTAL ZOOLOGY
Cardiac troponin T mutations result in allele-specific phenotypes in a mouse model for hypertrophic cardiomyopathy
JOURNAL OF CLINICAL INVESTIGATION
Identification of a contractile deficit in adult cardiac myocytes expressing hypertrophic cardiomyopathy-associated mutant troponin T proteins
JOURNAL OF CLINICAL INVESTIGATION
Nonmuscle tropomyosin-4 requires coexpression with other low molecular weight isoforms for binding to thin filaments in cardiomyocytes
JOURNAL OF CELL SCIENCE
Vertebrate isoforms of actin capping protein beta have distinct functions in vivo
JOURNAL OF CELL BIOLOGY
Effects of tropomyosin internal deletions on thin filament function
JOURNAL OF BIOLOGICAL CHEMISTRY
Functional consequences of troponin T mutations found in hypertrophic cardiomyopathy
JOURNAL OF BIOLOGICAL CHEMISTRY
Identification of a novel tropomodulin isoform, skeletal tropomodulin, that caps actin filament pointed ends in fast skeletal muscle
JOURNAL OF BIOLOGICAL CHEMISTRY
A post-transcriptional compensatory pathway in heterozygous ventricular myosin light chain 2-deficient mice results in lack of gene dosage effect during normal cardiac growth or hypertrophy
JOURNAL OF BIOLOGICAL CHEMISTRY
Ca2+ sensitization and potentiation of the maximum level of myofibrillar ATPase activity caused by mutations of troponin T found in familial hypertrophic cardiomyopathy
JOURNAL OF BIOLOGICAL CHEMISTRY
Roles for the troponin tail domain in thin filament assembly and regulation - A deletional study of cardiac troponin T
JOURNAL OF BIOLOGICAL CHEMISTRY